Field of the Invention
The present invention relates generally to the field of surgery, and more specifically to managing pressure within the eye by controlling the inflow of fluid using a specialized cassette during ophthalmic procedures such as the removal of a cataract.
Description of the Related Art
Phacoemulsification surgery has been successfully employed in the treatment of certain ocular problems, such as cataract surgery, including removal of a cataract-damaged lens and implanting an artificial intraocular lens. Phacoemulsification surgery typically involves removal of the cataract-damaged lens and may utilize a small incision at the edge of the cornea. Through the small incision, the surgeon then creates an opening in the capsule, i.e. membrane that encapsulates the lens.
Next, the surgeon may insert an ultrasonic probe, incorporated within the phacoemulsification handpiece, through the opening in the cornea and capsule accessing the damaged lens. The handpiece's ultrasonic actuated tip emulsifies the damaged lens sufficient to be evacuated by the handpiece. After the damaged natural lens is completely removed, the handpiece tip is withdrawn from the eye. The surgeon may now implant an intraocular lens into the space made available in the capsule.
While performing phacoemulsification surgical techniques, such as lens removal, it is necessary for the surgeon to be able to stop the flow of fluid into the phaco handpiece tip and into the ocular cavity. Stopping the flow generally entails reversing the flow of fluid, such as by reversing pump operation. One example of a need to stop flow is encountering an occlusion during emulsification of the damaged lens, wherein the tip of the phaco handpiece may become partially blocked or occluded. As the tip becomes further blocked or completely occluded, the vacuum in the aspiration line of the phaco handpiece builds proportionally. When the tip becomes unoccluded, due to removal or movement of the occlusion, the handpiece begins aspirating fluid to equalize the resulting pressure differential between the eye and the aspiration line. In order to stop the flow, the aspiration line can be vented to ambient pressure, the pump can be stopped, a pressure source can be reversed, such as a reversible peristaltic pump or an irrigation bottle or via an other mechanism known in the art. Flow may be stopped by the concept of reflux. Reflux occurs when pump pressure is reversed, thereby building pressure, and a positive pressure regulator is employed such that fluid flows backward once pressure is released.
When aspirating, venting, and/or refluxing, the present design typically employs two or more pumps. Any pump known in the art may be used with the present invention, including, but not limited to, peristaltic, venturi (wherein fluid flowing through a narrowing pipe produces vacuum as a result of the “Venturi effect”), and/or other flow or vacuum based pumps. In general, designs that operate efficiently in this dual-pump environment, wherein aspiration, venting, reflux, and/or irrigation may be initiated and terminated intermittently, can provide significant benefits in an operating room environment.
Many existing cassettes operate together with a single vacuum source, such as a single type of pump. When the phacoemulsification device has dual pump capability, it typically employs a specific replaceable cassette that enables dual pump operation and can be changed after a surgical procedure. A dual pump cassette exhibiting an efficient venting mechanism that can aspirate or irrigate fluid is highly beneficial.
Providing vacuum from different types of pumps or different types of devices enabling precision aspiration and irrigation can be desirable in an operating room situation. While certain multiple pump type cassettes have previously been offered, reliability in venting, aspirating and operating these cassettes can at times be imperfect, particularly in precise operating environments. Further, certain existing designs simply transfer all fluids into a reservoir, thereby rapidly filling up the reservoir, which is undesirable. If the reservoir is filled too rapidly or too frequently during a procedure, valuable time can be lost while the reservoir is drained. Additionally, previous designs have offered arrangements wherein both venting and aspiration are performed in a single line, such as a line connected to the reservoir. Separation of venting and aspiration functions can be advantageous and can provide improved performance over a single line used to perform both functions.
Also, certain previous designs include vent valves or other mechanisms which are sometimes undesirable. It would be beneficial to offer a dual pump cassette that employs minimal components or components that efficiently perform the aspiration and irrigation tasks required in the ocular surgical environment.
According to one aspect of the present design, there is provided a surgical cassette arrangement comprising a flow selector valve configured to operate with a handpiece to selectively irrigate and aspirate fluid with respect to an ocular region. The flow selector valve includes at least three ports, with one port fluidly connectable to the handpiece. The arrangement further includes a reservoir fluidly connected to a second port of the flow selector valve via a first flow segment and configured to receive fluid from the flow selector valve, and a collector fluidly connected to a third port of the flow selector valve via a second flow segment and configured to receive fluid from the flow selector valve and from the reservoir. The flow selector valve selectively controls aspiration and reflux/venting flow to the handpiece and ocular region.
According to another aspect of the present design, there is provided a method for selectively venting and aspirating fluid to and from a handpiece employed in an ocular surgical procedure. The method includes providing a first pumping operation and a second pumping operation and selecting operation between the first pumping operation and the second pumping operation using a flow selector valve. The first pumping operation controls fluid flow to and from an eye using a first pump fluidly connecting the flow selector valve to a first fluid pathway via a first port in the selector valve. The second pumping operation controls fluid flow to and from the eye by varying pressure inside a reservoir fluidly connected to the flow selector valve via a second fluid pathway connected to a second port in the flow selector valve.
These and other advantages of the present invention will become apparent to those skilled in the art from the following detailed description of the invention and the accompanying drawings.
The present invention is illustrated by way of example, and not by way of limitation, in the figures of the accompanying drawings in which:
The following description and the drawings illustrate specific embodiments sufficient to enable those skilled in the art to practice the system and method described. Other embodiments may incorporate structural, logical, process and other changes. Examples merely typify possible variations. Individual components and functions are generally optional unless explicitly required, and the sequence of operations may vary. Portions and features of some embodiments may be included in or substituted for those of others.
The present design is directed to controlling pressure within an eye during an ocular procedure that involves either aspiration or irrigation of the eye via a handpiece connected to a phacoemulsification system. The present arrangement may include a pump component configured to provide either aspiration or venting for purposes of pressure control when connected to the phacoemulsification system. For example, the phacoemulsification system may provide for peristaltic aspiration, where a surgeon performing an ocular surgery may balance or equalize a pressure differential between the eye and the aspiration line by venting in the situation where the handpiece tip becomes occluded. During peristaltic aspiration with no occlusion, the system moves fluid from the eye to a collector, where the collector may include a device such as a collection bag. In order to vent or reflux fluid into the eye, the present design reverses the pumping direction or vents to atmospheric pressure, and reversing pumping direction typically occurs at a very rapid rate.
The system may include a vacuum pump arrangement configured to provide either aspiration or venting for purposes of accurate pressure control within the eye. For example, the system can provide vacuum regulated venting, where a surgeon performing an ocular surgical procedure may need to balance or equalize a pressure differential due to an occlusion. During vacuum regulator venting, the system moves fluid from the holding tank or reservoir to the eye by increasing the pressure within or associated with the reservoir. In order to aspirate the eye, the vacuum regulator reverses the fluid flow, removing fluid from the eye by reducing the pressure within the reservoir.
The present design includes a surgical cassette arrangement configured for use with a medical instrument system, such as a phacoemulsification system, wherein the system is configured with two or more pumps to control the flow of fluid into the phaco handpiece tip and ocular region, where the cassette arrangement supports both reflux, venting and aspiration functionality. The present design provides a flow selector valve configured to provide multiple pathways for aspiration, venting, and/or reflux. The result is a design that operates better in certain common circumstances than designs previously available.
The present design is intended to provide a reliable, noninvasive, and efficient cassette venting apparatus and method for use in a medical instrument system for use in efficiently controlling the flow of fluids into and out of an eye during an ocular procedure.
Note that as used herein, the phrase “fluidly connected” or “fluidly connectable” is intended to be employed as broadly as possible, including but not limited to meaning, when used in connection with two components, that fluid may pass between the two components even if they are remotely located and/or connected via intermediate components or connectors, either operational or non-operational. Thus as used herein, “fluidly connected” or “fluidly connectable” indicates fluid can flow or is capable of flowing between components, even if pumping components or other intermediate components facilitating fluid flow are not operating or are restricting flow.
System Example
While the present design may be used in various environments and applications, it will be discussed herein with a particular emphasis on an environment where a surgeon or health care practitioner performs. For example, one embodiment of the present design is in or with an ocular surgical system that comprises an independent graphical user interface (GUI) host module, an instrument host module, a GUI device, and a controller module, such as a foot switch, to control the surgical system.
A switch module associated with foot pedal 104 may transmit control signals relating internal physical and virtual switch position information as input to the instrument host 102 over serial communications cable 105 (although footpedal 104 may be connected wirelessly). Instrument host 102 may provide a database file system for storing configuration parameter values, programs, and other data saved in a storage device (not shown). In addition, the database file system may be realized on the GUI host 101 or any other subsystem (not shown) that could accommodate such a file system.
The phacoemulsification/vitrectomy system 100 has a handpiece 110 that includes a needle and electrical means, typically a piezoelectric crystal, for ultrasonically vibrating the needle. The instrument host 102 supplies power on line 111 to a phacoemulsification/vitrectomy handpiece 110. An irrigation fluid source 112 can be fluidly coupled to handpiece 110 through line 113. The irrigation fluid and ultrasonic power are applied by handpiece 110 to an eye, or affected area or region, indicated diagrammatically by block 114. Alternatively, the irrigation source may be routed to eye 114 through a separate pathway independent of the handpiece. Aspiration is provided to eye 114 by one or more pumps (not shown), such as a peristaltic pump, via the instrument host 102, through lines 115 and 116. A surgeon/operator may select an amplitude of electrical pulses either using the footpedal, via the instrument host, GUI host, and/or by voice command.
In combination with phacoemulsification system 100, the present system enables aspiration, venting, or reflux functionality in or with the phacoemulsification system and may comprise components including, but not limited to, a flow selector valve, two or more pumps, a reservoir, and a collector, such as a collection bag or a device having similar functionality. The collector in the present design collects aspirant from the ocular surgical procedure.
The present design effectively splits the aspiration line from handpiece 110 into at least two separate fluid pathways where one is connected to collector 206 and the other to the air/fluid reservoir 204, which is also connected to collector 206. Splitting the fluid pathways in this way allows one line designated for vacuum regulated aspiration, venting, and/or reflux and the other line designated for peristaltic aspiration, venting, and/or reflux. The vacuum regulated aspiration line connects to reservoir 204, wherein fluid may be aspirated, vented, and/or refluxed to or from reservoir 204 through the line. The peristaltic line connects directly to the collector and aspirates, vents, and/or refluxes through the aspiration line without requiring a connection to reservoir 204.
Surgical cassette venting system 200 may include a fluid vacuum sensor 201, flow selector valve 202, reservoir 204, collector 206, and fluid pathways, such as interconnecting surgical tubing, as shown in
Cassette arrangement 250 is illustrated in
Referring to
The flow selector valve 202 illustrated in
It is also envisioned that flow selector valve 202 may be or comprise one or more pinch valves. The one or more pinch valves may be located along fluid pathway 221 and/or 223, or any other fluid pathway as discussed herein. Further, there may be one or more fluid pathways coupled with handpiece 110 and extending to various components of cassette arrangement 250, including a first fluid pathway from fluid vacuum sensor 201 to collector 206 via pump 203 and/or a second fluid pathway to reservoir 204. In another embodiment, fluid pathway 220 is a single fluid pathway that couples with fluid vacuum sensor 201. From fluid vacuum sensor 201, the single fluid pathway 220 may divide into two fluid pathways, one to collector 206 via pump 203 and one to reservoir 204. Further, one or more pinch valves and/or flow selector valve 202 may be located along the fluid pathway between fluid vacuum sensor 201 and collector 206 and/or between fluid vacuum sensor 201 and reservoir 204.
Thus while a single flow selector valve 202 is illustrated in
The present design's fluid vacuum sensor 201, for example a strain gauge or other suitable component, may communicate or signal information to instrument host 102 to provide the amount of vacuum sensed in the handpiece fluid pathway 220. Instrument host 102 may determine the actual amount of vacuum present based on the communicated information.
Fluid vacuum sensor 201 monitors flow into and out of the line, and can be used to determine when flow should be reversed, such as encountering a certain pressure level (e.g. in the presence of an occlusion), and based on values obtained from the fluid vacuum sensor 201, the system may control selector valve 202 and the pumps illustrated. It is to be understood that while components presented in
With respect to fluid vacuum sensor 201, emergency conditions such as a dramatic drop or rise in pressure may result in a type of fail-safe operation. The present design employs fluid vacuum sensor 201 to monitor the flow conditions and provide signals representing flow conditions to the system such as via instrument host 102 for the purpose of controlling components shown including but not limited to flow selector valve 202 and the pumps shown.
Multiple aspiration and ventilation options are available in the design of
In the arrangement where the cassette system flow selector valve 202 connects handpiece 110 with reservoir 204, the present design allows for aspiration from eye 114 directly to reservoir 204 as indicated by directional flow arrow ‘X’ 238, and arrow C 240 in
Although venting is shown from BSS bottle 112, venting and/or irrigation is not represented in
Reservoir 204 may contain air in section 211 and fluid in section 212. Surgical cassette system 200 may connect reservoir 204 with collector 206 using fluid pathways, such as surgical tubing or similar items. In this arrangement, pump 205 may operate in a clockwise direction in the direction of arrow 228 to remove fluid from the reservoir 204 through fluid pathway 227 and deliver the fluid to collector 206 using fluid pathway 229. The present design illustrates a peristaltic pump as pump 205, a component within instrument host 102, but other types of pumps may be employed. This configuration may enable the surgical cassette 200 to remove unwanted fluid and/or material from reservoir 204.
The fluid pathways or flow segments of surgical cassette system 200 may include the fluid connections, for example flexible tubing, between each component represented with solid lines in
Vacuum pump arrangement 207 is typically connected with instrument host 102, and may be connected with reservoir 204 via fluid pathway or flow segment 230. In the configuration shown, vacuum pump arrangement 207 includes a pump 208, such as a venturi pump and an optional pressure regulator 209 (and valve (not shown)), but other configurations are possible. In this arrangement, vacuum pump arrangement 207 may operate to remove air from the top of reservoir 204 and deliver the air to atmosphere (not shown). Removal of air from reservoir 204 in this manner may reduce the pressure within the reservoir, which reduces the pressure in the attached fluid pathway 226, to a level less than the pressure within eye 114. A lower reservoir pressure connected through flow selector valve 202 may cause fluid to move from the eye, thereby providing aspiration. The vacuum pump arrangement 207 and reservoir 204 can be used to control fluid flow into and out of reservoir 204.
The optional pressure regulator 209 may operate to add air to the top of reservoir 204 which in turn increases pressure and may force the air-fluid boundary 213 to move downward. Adding air into reservoir 204 in this manner may increase the air pressure within the reservoir, which increases the pressure in the attached fluid aspiration line 226 to a level greater than the pressure within eye 114. A higher reservoir pressure connected through flow selector valve 203 may cause fluid to move toward eye 114, thereby providing venting or reflux.
An alternate method of creating positive pressure in reservoir 204 is running pump 205 in a counter-clockwise direction. Running pump 205 in a counter-clockwise direction will increase the amount of air in section 211 in reservoir 204.
It is to be noted that higher pressure in reservoir 204 causes more fluid flow and potentially more reflux from reservoir 204 to handpiece 110. If the lines from the reservoir 204 are plugged or otherwise occluded, providing pressure to reservoir 204 can result in venting and/or reflux. Venting in this context results in the release of pressure. Reflux occurs when a pump is reversed sending fluid in the opposite direction of normal flow (e.g. toward the eye). In a reflux condition, the surgeon can control the amount of fluid flowing back through the fluid pathways and components.
The present design may involve peristaltic operation, aspirating fluid from eye 114 to collector 206 illustrated in
In the arrangement where the flow selector valve 202 connects handpiece 110 with BSS bottle 112, the present design may allow for venting of fluid to eye 114 directly from BSS bottle 112 and/or the line between flow selector valve 202 and BSS bottle 112, where fluid from BSS bottle 112 and/or the line flows toward and through flow selector valve 202. The fluid flow continues to flow toward and through flow selector valve 202 in the direction indicated by arrow 321. In order to vent from BSS bottle 112, instrument host 102 may signal flow selector valve 202 to connect port ‘0’ to port ‘1’. When the flow selector valve 202 switches to position ‘1,’ fluid may flow from BSS bottle 112 and/or the line between BSS bottle 112 and flow selector valve 202 to handpiece 110 as indicated by directional arrows 322 and 321 as shown in
In the configuration of
The present design may alternately employ vacuum pump arrangement 207 to aspirate fluid from eye 114 to reservoir 204 as illustrated in
In sum, the present design surgical cassette system provides for aspiration, venting, and/or reflux using pumping operations. A plurality of pumps are typically employed, including a first pump and a second pump, where a first pump may be pump 203, shown as a peristaltic pump in
The instrument host 102 may provide a signal to position or switch flow selector valve 202 for desired peristaltic or vacuum regulated operation. Aspiration, venting, and/or reflux may be controlled in various ways, including but not limited to switching offered to the surgeon on the instrument host 102, switching via a switch such as one provided on handpiece 110 or via a footswitch, or via automatic or semi-automatic operation, wherein pressure is sensed at some point, such as coming from the handpiece to the instrument host at sensor 201 or separately sensed by a sensor placed in the ocular region with pressure signals being provided to the instrument host 102. In general, automatic or semi-automatic operation entails sensing a drop or rise in pressure and either aspirating fluid to or venting fluid from the ocular region or eye 114. In any circumstance, the surgeon or other personnel are provided with the ability to run the pumps in any available direction, such as for cleaning purposes.
Other pumping states may be provided as discussed herein and based on the desires of personnel performing the surgical procedure. For example, in the case of the surgeon desiring aspiration operation as shown in
Certain additional functionality or components may be provided in the current design. For example, a valve (not shown) may be located between pump 203 and flow selector valve 202 or between pump 203 and handpiece 110 in the design, such as in the design of
The design presented herein and the specific aspects illustrated are meant not to be limiting, but may include alternate components while still incorporating the teachings and benefits of the invention. While the invention has thus been described in connection with specific embodiments thereof, it will be understood that the invention is capable of further modifications. This application is intended to cover any variations, uses or adaptations of the invention following, in general, the principles of the invention, and including such departures from the present disclosure as come within known and customary practice within the art to which the invention pertains.
The foregoing description of specific embodiments reveals the general nature of the disclosure sufficiently that others can, by applying current knowledge, readily modify and/or adapt the system and method for various applications without departing from the general concept. Therefore, such adaptations and modifications are within the meaning and range of equivalents of the disclosed embodiments. The phraseology or terminology employed herein is for the purpose of description and not of limitation.
This application is a divisional application and claims priority to U.S. patent application Ser. No. 12/613,582, which was filed on Nov. 6, 2009 and issued as U.S. Pat. No. 9,005,157 on Apr. 14, 2015, which claims priority to U.S. Provisional Application No. 61/112,651, which was filed on Nov. 7, 2008, the entire contents of which are hereby incorporated by reference in their entirety for all purposes as if fully set forth herein.
Number | Name | Date | Kind |
---|---|---|---|
1848024 | Owen | Mar 1932 | A |
2123781 | Huber | Jul 1938 | A |
2990616 | Balamuth et al. | Jul 1961 | A |
3076904 | Claus et al. | Feb 1963 | A |
3116697 | Theodore | Jan 1964 | A |
3439680 | Thomas, Jr. | Apr 1969 | A |
3526219 | Lewis | Sep 1970 | A |
3781142 | Zweig | Dec 1973 | A |
3857387 | Shock | Dec 1974 | A |
4017828 | Watanabe et al. | Apr 1977 | A |
4037491 | Newbold | Jul 1977 | A |
4189286 | Murry et al. | Feb 1980 | A |
4193004 | Lobdell et al. | Mar 1980 | A |
4247784 | Henry | Jan 1981 | A |
4276023 | Phillips et al. | Jun 1981 | A |
4286464 | Tauber et al. | Sep 1981 | A |
4537561 | Xanthopoulos | Aug 1985 | A |
4564342 | Weber et al. | Jan 1986 | A |
4590934 | Malis et al. | May 1986 | A |
4662829 | Nehring | May 1987 | A |
4665621 | Ackerman et al. | May 1987 | A |
4706687 | Rogers et al. | Nov 1987 | A |
4713051 | Steppe et al. | Dec 1987 | A |
4757814 | Wang et al. | Jul 1988 | A |
4758220 | Sundblom et al. | Jul 1988 | A |
4758238 | Sundblom et al. | Jul 1988 | A |
4772263 | Dorman et al. | Sep 1988 | A |
4773897 | Scheller et al. | Sep 1988 | A |
4818186 | Pastrone et al. | Apr 1989 | A |
4819317 | Bauer et al. | Apr 1989 | A |
4837857 | Scheller et al. | Jun 1989 | A |
4920336 | Meijer | Apr 1990 | A |
4921477 | Davis | May 1990 | A |
4925444 | Orkin et al. | May 1990 | A |
4933843 | Scheller et al. | Jun 1990 | A |
4941518 | Williams et al. | Jul 1990 | A |
4954960 | Lo et al. | Sep 1990 | A |
4961424 | Kubota et al. | Oct 1990 | A |
4965417 | Massie | Oct 1990 | A |
4983901 | Lehmer | Jan 1991 | A |
4998972 | Chin et al. | Mar 1991 | A |
5006110 | Garrison et al. | Apr 1991 | A |
5020535 | Parker et al. | Jun 1991 | A |
5026387 | Thomas | Jun 1991 | A |
5032939 | Mihara et al. | Jul 1991 | A |
5039973 | Carballo | Aug 1991 | A |
5091656 | Gahn | Feb 1992 | A |
5108367 | Epstein et al. | Apr 1992 | A |
5110270 | Morrick | May 1992 | A |
5125891 | Hossain et al. | Jun 1992 | A |
5160317 | Costin | Nov 1992 | A |
5195960 | Hossain et al. | Mar 1993 | A |
5195961 | Takahashi et al. | Mar 1993 | A |
5195971 | Sirhan | Mar 1993 | A |
5230614 | Zanger et al. | Jul 1993 | A |
5242404 | Conley et al. | Sep 1993 | A |
5249121 | Baum et al. | Sep 1993 | A |
5267956 | Beuchat | Dec 1993 | A |
5268624 | Zanger | Dec 1993 | A |
5271379 | Phan et al. | Dec 1993 | A |
5282787 | Wortrich | Feb 1994 | A |
5323543 | Steen et al. | Jun 1994 | A |
5342293 | Zanger | Aug 1994 | A |
5350357 | Kamen et al. | Sep 1994 | A |
5351676 | Putman | Oct 1994 | A |
5354268 | Peterson et al. | Oct 1994 | A |
5378126 | Abrahamson et al. | Jan 1995 | A |
5388569 | Kepley | Feb 1995 | A |
5429601 | Conley et al. | Jul 1995 | A |
5454783 | Grieshaber et al. | Oct 1995 | A |
5464391 | Devale | Nov 1995 | A |
5470211 | Knott et al. | Nov 1995 | A |
5470312 | Zanger et al. | Nov 1995 | A |
5499969 | Beuchat et al. | Mar 1996 | A |
5520652 | Peterson | May 1996 | A |
5533976 | Zaleski et al. | Jul 1996 | A |
5549461 | Newland | Aug 1996 | A |
5554894 | Sepielli | Sep 1996 | A |
5561575 | Eways | Oct 1996 | A |
5569188 | MacKool | Oct 1996 | A |
5580347 | Reimels | Dec 1996 | A |
5591127 | Barwick et al. | Jan 1997 | A |
5653887 | Wahl et al. | Aug 1997 | A |
5657000 | Ellingboe | Aug 1997 | A |
5676530 | Nazarifar | Oct 1997 | A |
5676649 | Boukhny et al. | Oct 1997 | A |
5676650 | Grieshaber et al. | Oct 1997 | A |
5693020 | Rauh | Dec 1997 | A |
5697898 | Devine | Dec 1997 | A |
5697910 | Cole et al. | Dec 1997 | A |
5700240 | Barwick et al. | Dec 1997 | A |
5724264 | Rosenberg et al. | Mar 1998 | A |
5728130 | Ishikawa et al. | Mar 1998 | A |
5733256 | Costin | Mar 1998 | A |
5733263 | Wheatman | Mar 1998 | A |
5745647 | Krause | Apr 1998 | A |
5746713 | Hood et al. | May 1998 | A |
5747824 | Jung et al. | May 1998 | A |
5777602 | Schaller et al. | Jul 1998 | A |
5805998 | Kodama | Sep 1998 | A |
5807075 | Jacobsen et al. | Sep 1998 | A |
5810765 | Oda | Sep 1998 | A |
5810766 | Barnitz et al. | Sep 1998 | A |
5830176 | MacKool | Nov 1998 | A |
5843109 | Mehta et al. | Dec 1998 | A |
5859642 | Jones | Jan 1999 | A |
5871492 | Sorensen | Feb 1999 | A |
5879298 | Drobnitzky et al. | Mar 1999 | A |
5883615 | Fago et al. | Mar 1999 | A |
5899674 | Jung et al. | May 1999 | A |
5928257 | Kablik et al. | Jul 1999 | A |
5938655 | Bisch et al. | Aug 1999 | A |
5983749 | Holtorf | Nov 1999 | A |
6002484 | Rozema et al. | Dec 1999 | A |
6024428 | Uchikata | Feb 2000 | A |
6028387 | Boukhny | Feb 2000 | A |
6062829 | Ognier | May 2000 | A |
6077285 | Boukhny | Jun 2000 | A |
6086598 | Appelbaum et al. | Jul 2000 | A |
6109895 | Ray et al. | Aug 2000 | A |
6117126 | Appelbaum et al. | Sep 2000 | A |
6139320 | Hahn | Oct 2000 | A |
6150623 | Chen | Nov 2000 | A |
6159175 | Strukel et al. | Dec 2000 | A |
6179829 | Bisch et al. | Jan 2001 | B1 |
6200287 | Keller et al. | Mar 2001 | B1 |
6219032 | Rosenberg et al. | Apr 2001 | B1 |
6251113 | Appelbaum et al. | Jun 2001 | B1 |
6258111 | Ross et al. | Jul 2001 | B1 |
6260434 | Holtorf | Jul 2001 | B1 |
6360630 | Holtorf | Mar 2002 | B2 |
6368269 | Lane | Apr 2002 | B1 |
6411062 | Baranowski et al. | Jun 2002 | B1 |
6424124 | Ichihara et al. | Jul 2002 | B2 |
6436072 | Kullas et al. | Aug 2002 | B1 |
6452120 | Chen | Sep 2002 | B1 |
6452123 | Chen | Sep 2002 | B1 |
6491661 | Boukhny et al. | Dec 2002 | B1 |
6511454 | Nakao et al. | Jan 2003 | B1 |
6537445 | Muller | Mar 2003 | B2 |
6561999 | Nazarifar et al. | May 2003 | B1 |
6595948 | Suzuki et al. | Jul 2003 | B2 |
6632214 | Morgan et al. | Oct 2003 | B2 |
6674030 | Chen et al. | Jan 2004 | B2 |
6780166 | Kanda et al. | Aug 2004 | B2 |
6830555 | Rockley et al. | Dec 2004 | B2 |
6852092 | Kadziauskas et al. | Feb 2005 | B2 |
6862951 | Peterson et al. | Mar 2005 | B2 |
6908451 | Brody et al. | Jun 2005 | B2 |
6962488 | Davis et al. | Nov 2005 | B2 |
6962581 | Thoe | Nov 2005 | B2 |
6986753 | Bui | Jan 2006 | B2 |
7011761 | Muller | Mar 2006 | B2 |
7012203 | Hanson et al. | Mar 2006 | B2 |
7070578 | Leukanech et al. | Jul 2006 | B2 |
7073083 | Litwin, Jr. et al. | Jul 2006 | B2 |
7087049 | Nowlin et al. | Aug 2006 | B2 |
7103344 | Menard | Sep 2006 | B2 |
7167723 | Zhang | Jan 2007 | B2 |
7168930 | Cull et al. | Jan 2007 | B2 |
7169123 | Kadziauskas et al. | Jan 2007 | B2 |
7236766 | Freeburg | Jun 2007 | B2 |
7236809 | Fischedick et al. | Jun 2007 | B2 |
7242765 | Hairston | Jul 2007 | B2 |
7244240 | Nazarifar et al. | Jul 2007 | B2 |
7289825 | Fors et al. | Oct 2007 | B2 |
7300264 | Souza | Nov 2007 | B2 |
7316664 | Kadziauskas et al. | Jan 2008 | B2 |
7336976 | Ito | Feb 2008 | B2 |
7381917 | Dacquay et al. | Jun 2008 | B2 |
7439463 | Brenner et al. | Oct 2008 | B2 |
7465285 | Hutchinson et al. | Dec 2008 | B2 |
7470277 | Finlay et al. | Dec 2008 | B2 |
7526038 | McNamara | Apr 2009 | B2 |
7591639 | Kent | Sep 2009 | B2 |
7731484 | Yamamoto et al. | Jun 2010 | B2 |
7776006 | Childers et al. | Aug 2010 | B2 |
7785316 | Claus et al. | Aug 2010 | B2 |
7811255 | Boukhny et al. | Oct 2010 | B2 |
7883521 | Rockley et al. | Feb 2011 | B2 |
7921017 | Claus et al. | Apr 2011 | B2 |
7967777 | Edwards et al. | Jun 2011 | B2 |
8070712 | Muri et al. | Dec 2011 | B2 |
8075468 | Min et al. | Dec 2011 | B2 |
8157792 | Dolliver et al. | Apr 2012 | B2 |
9033940 | Muri et al. | May 2015 | B2 |
9658468 | Dai | May 2017 | B2 |
20010023331 | Kanda et al. | Sep 2001 | A1 |
20010047166 | Wuchinich | Nov 2001 | A1 |
20010051788 | Paukovits et al. | Dec 2001 | A1 |
20020004657 | Morgan et al. | Jan 2002 | A1 |
20020007671 | Lavi et al. | Jan 2002 | A1 |
20020019215 | Romans | Feb 2002 | A1 |
20020019607 | Bui | Feb 2002 | A1 |
20020045887 | DeHoogh et al. | Apr 2002 | A1 |
20020070840 | Fischer et al. | Jun 2002 | A1 |
20020098859 | Murata | Jul 2002 | A1 |
20020137007 | Beerstecher | Sep 2002 | A1 |
20020179462 | Silvers | Dec 2002 | A1 |
20020183693 | Peterson et al. | Dec 2002 | A1 |
20030028091 | Simon et al. | Feb 2003 | A1 |
20030050619 | Mooijman et al. | Mar 2003 | A1 |
20030083016 | Evans et al. | May 2003 | A1 |
20030108429 | Angelini et al. | Jun 2003 | A1 |
20030125717 | Whitman | Jul 2003 | A1 |
20030224729 | Arnold | Dec 2003 | A1 |
20030226091 | Platenberg et al. | Dec 2003 | A1 |
20040019313 | Childers et al. | Jan 2004 | A1 |
20040037724 | Haser et al. | Feb 2004 | A1 |
20040097868 | Kadziauskas et al. | May 2004 | A1 |
20040127840 | Gara et al. | Jul 2004 | A1 |
20040193182 | Yaguchi et al. | Sep 2004 | A1 |
20040212344 | Tamura et al. | Oct 2004 | A1 |
20040215127 | Kadziauskas et al. | Oct 2004 | A1 |
20040224641 | Sinn | Nov 2004 | A1 |
20040253129 | Sorensen et al. | Dec 2004 | A1 |
20040267136 | Yaguchi et al. | Dec 2004 | A1 |
20050039567 | Peterson et al. | Feb 2005 | A1 |
20050054971 | Steen et al. | Mar 2005 | A1 |
20050069419 | Cull et al. | Mar 2005 | A1 |
20050070859 | Cull et al. | Mar 2005 | A1 |
20050070871 | Lawton et al. | Mar 2005 | A1 |
20050095153 | Demers et al. | May 2005 | A1 |
20050103607 | Mezhinsky | May 2005 | A1 |
20050109595 | Mezhinsky et al. | May 2005 | A1 |
20050118048 | Traxinger | Jun 2005 | A1 |
20050119679 | Rabiner et al. | Jun 2005 | A1 |
20050130098 | Warner | Jun 2005 | A1 |
20050187513 | Rabiner et al. | Aug 2005 | A1 |
20050197131 | Ikegami | Sep 2005 | A1 |
20050209552 | Beck et al. | Sep 2005 | A1 |
20050228266 | McCombs | Oct 2005 | A1 |
20050236936 | Shiv et al. | Oct 2005 | A1 |
20050245888 | Cull | Nov 2005 | A1 |
20050261628 | Boukhny et al. | Nov 2005 | A1 |
20050267504 | Boukhny et al. | Dec 2005 | A1 |
20060035585 | Washiro | Feb 2006 | A1 |
20060036180 | Boukhny et al. | Feb 2006 | A1 |
20060041220 | Boukhny et al. | Feb 2006 | A1 |
20060046659 | Haartsen et al. | Mar 2006 | A1 |
20060074405 | Malackowski et al. | Apr 2006 | A1 |
20060078448 | Holden | Apr 2006 | A1 |
20060114175 | Boukhny | Jun 2006 | A1 |
20060145540 | Mezhinsky | Jul 2006 | A1 |
20060219049 | Horvath et al. | Oct 2006 | A1 |
20060219962 | Dancs et al. | Oct 2006 | A1 |
20060224107 | Claus et al. | Oct 2006 | A1 |
20060236242 | Boukhny et al. | Oct 2006 | A1 |
20070016174 | Millman et al. | Jan 2007 | A1 |
20070049898 | Hopkins et al. | Mar 2007 | A1 |
20070060926 | Escaf | Mar 2007 | A1 |
20070073214 | Dacquay et al. | Mar 2007 | A1 |
20070073309 | Kadziauskas et al. | Mar 2007 | A1 |
20070078379 | Boukhny et al. | Apr 2007 | A1 |
20070085611 | Gerry et al. | Apr 2007 | A1 |
20070107490 | Artsyukhovich et al. | May 2007 | A1 |
20070231205 | Williams et al. | Oct 2007 | A1 |
20070249942 | Salehi et al. | Oct 2007 | A1 |
20070287959 | Walter et al. | Dec 2007 | A1 |
20080033342 | Staggs | Feb 2008 | A1 |
20080066542 | Gao | Mar 2008 | A1 |
20080082040 | Kubler et al. | Apr 2008 | A1 |
20080112828 | Muri et al. | May 2008 | A1 |
20080114290 | King et al. | May 2008 | A1 |
20080114291 | Muri et al. | May 2008 | A1 |
20080114300 | Muri et al. | May 2008 | A1 |
20080114311 | Muri et al. | May 2008 | A1 |
20080114312 | Muri et al. | May 2008 | A1 |
20080114387 | Hertweck et al. | May 2008 | A1 |
20080125695 | Hopkins et al. | May 2008 | A1 |
20080125697 | Gao | May 2008 | A1 |
20080125698 | Gerg et al. | May 2008 | A1 |
20080129695 | Li | Jun 2008 | A1 |
20080146989 | Zacharias | Jun 2008 | A1 |
20080200878 | Davis et al. | Aug 2008 | A1 |
20080243105 | Horvath | Oct 2008 | A1 |
20080262476 | Krause et al. | Oct 2008 | A1 |
20080281253 | Injev et al. | Nov 2008 | A1 |
20080294087 | Steen et al. | Nov 2008 | A1 |
20080312594 | Urich et al. | Dec 2008 | A1 |
20090005712 | Raney | Jan 2009 | A1 |
20090005789 | Charles | Jan 2009 | A1 |
20090048607 | Rockley | Feb 2009 | A1 |
20090087327 | Voltenburg, Jr. et al. | Apr 2009 | A1 |
20090124974 | Crank et al. | May 2009 | A1 |
20090163853 | Cull et al. | Jun 2009 | A1 |
20100036256 | Boukhny et al. | Feb 2010 | A1 |
20100057016 | Dale et al. | Mar 2010 | A1 |
20100069825 | Raney | Mar 2010 | A1 |
20100069828 | Steen et al. | Mar 2010 | A1 |
20100140149 | Fulkerson | Jun 2010 | A1 |
20100152685 | Goh | Jun 2010 | A1 |
20100185150 | Zacharias | Jul 2010 | A1 |
20100249693 | Links | Sep 2010 | A1 |
20100280435 | Raney et al. | Nov 2010 | A1 |
20110092887 | Wong et al. | Apr 2011 | A1 |
20110092924 | Wong et al. | Apr 2011 | A1 |
20110092962 | Ma et al. | Apr 2011 | A1 |
20110098721 | Tran et al. | Apr 2011 | A1 |
20110160646 | Kadziauskas et al. | Jun 2011 | A1 |
20110208047 | Fago | Aug 2011 | A1 |
20110251569 | Turner et al. | Oct 2011 | A1 |
20120065580 | Gerg et al. | Mar 2012 | A1 |
20120078181 | Smith et al. | Mar 2012 | A1 |
20120083735 | Pfouts | Apr 2012 | A1 |
20120083736 | Pfouts et al. | Apr 2012 | A1 |
20120083800 | Andersohn | Apr 2012 | A1 |
20130072853 | Wong et al. | Mar 2013 | A1 |
20130169412 | Roth | Jul 2013 | A1 |
20130184676 | Kamen et al. | Jul 2013 | A1 |
20130245543 | Gerg et al. | Sep 2013 | A1 |
20130267892 | Woolford et al. | Oct 2013 | A1 |
20130289475 | Muri et al. | Oct 2013 | A1 |
20130303978 | Ross | Nov 2013 | A1 |
20130336814 | Kamen et al. | Dec 2013 | A1 |
20140178215 | Baxter et al. | Jun 2014 | A1 |
20140188076 | Kamen et al. | Jul 2014 | A1 |
20140276424 | Davis et al. | Sep 2014 | A1 |
20160151564 | Magers et al. | Jun 2016 | A1 |
Number | Date | Country |
---|---|---|
2006235983 | May 2007 | AU |
2662797A | Mar 2008 | CA |
3826414 | Feb 1989 | DE |
56019 | Jul 1982 | EP |
424687 | May 1991 | EP |
619993 | Oct 1994 | EP |
1010437 | Jun 2000 | EP |
1072265 | Jan 2001 | EP |
1113562 | Jul 2001 | EP |
1310267 | May 2003 | EP |
1464310 | Oct 2004 | EP |
1469440 | Oct 2004 | EP |
1550406 | Jul 2005 | EP |
1704839 | Sep 2006 | EP |
1779879 | May 2007 | EP |
1787606 | May 2007 | EP |
1849443 | Oct 2007 | EP |
1849444 | Oct 2007 | EP |
1857128 | Nov 2007 | EP |
1867349 | Dec 2007 | EP |
1310267 | Jan 2008 | EP |
1873501 | Jan 2008 | EP |
1900347 | Mar 2008 | EP |
1925274 | May 2008 | EP |
1867349 | Nov 2008 | EP |
2264369 | Dec 2006 | ES |
2230301 | Oct 1990 | GB |
2352887 | Feb 2001 | GB |
2438679 | Dec 2007 | GB |
S5724482 | Feb 1982 | JP |
S58167333 | Oct 1983 | JP |
S62204463 | Sep 1987 | JP |
2005195653 | Jul 2005 | JP |
2008188110 | Aug 2008 | JP |
9220310 | Nov 1992 | WO |
9315777 | Aug 1993 | WO |
9317729 | Sep 1993 | WO |
9324082 | Dec 1993 | WO |
9405340 | Mar 1994 | WO |
9632144 | Oct 1996 | WO |
9737700 | Oct 1997 | WO |
9818507 | May 1998 | WO |
9917818 | Apr 1999 | WO |
0000096 | Jan 2000 | WO |
0070225 | Nov 2000 | WO |
0122696 | Mar 2001 | WO |
0226286 | Apr 2002 | WO |
0228449 | Apr 2002 | WO |
0234314 | May 2002 | WO |
03102878 | Dec 2003 | WO |
04096360 | Nov 2004 | WO |
2004114180 | Dec 2004 | WO |
05084728 | Sep 2005 | WO |
05092023 | Oct 2005 | WO |
05092047 | Oct 2005 | WO |
06101908 | Sep 2006 | WO |
06125280 | Nov 2006 | WO |
2007121144 | Oct 2007 | WO |
2007143677 | Dec 2007 | WO |
2007143797 | Dec 2007 | WO |
2007149637 | Dec 2007 | WO |
2008030872 | Mar 2008 | WO |
2008060859 | May 2008 | WO |
2008060902 | May 2008 | WO |
2008060995 | May 2008 | WO |
2009123547 | Oct 2009 | WO |
2010054146 | May 2010 | WO |
2010054225 | May 2010 | WO |
2010151704 | Dec 2010 | WO |
2012151062 | Nov 2012 | WO |
2013142009 | Sep 2013 | WO |
2015009945 | Jan 2015 | WO |
Entry |
---|
Boyd, “Preparing for the Transition” in: The Art and the Science of Cataract Surgery, Chapter 7, 2001, pp. 93-133. |
Merritt R., et al., Wireless Nets Starling to link Medical Gear [online] 2004 [retrieved on Feb. 12, 2007]. Retrieved from the Internet:. |
Phacoemulsification, [online] [retrieved on Jul. 1, 2009]. Retrieved from the Internet: , 2 pages. |
European Search Report for Application No. EP10164058, dated Jun. 25, 2010, 2 pages. |
European Search Report for Application No. EP13184138.9, dated Oct. 24, 2013, 7 pages. |
Examination Report dated Mar. 28, 2012 for European Application No. EP09791072 filed Jul. 31, 2009, 3 pages. |
International Search Report and Written Opinion for Application No. PCT/US2016/049970, dated Dec. 5, 2016, 12 pages. |
Definition of “Parameter”, Retrieved from the Internet:, Retrieved on Aug. 9, 2016. |
International Search Report and Written Opinion for Application No. PCT/US2015/066036, dated Jul. 4, 2016, 20 pages. |
International Search Report and Written Opinion for Application No. PCT/US2016/061648, dated Feb. 7, 2017, 12 pages. |
English Human Translation of JP57024482 from Feb. 9, 1982. |
Number | Date | Country | |
---|---|---|---|
20150209490 A1 | Jul 2015 | US |
Number | Date | Country | |
---|---|---|---|
61112651 | Nov 2008 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 12613582 | Nov 2009 | US |
Child | 14679679 | US |