SUSTAINED RELEASE NALTREXONE AS TRTMT FOR ALCM - SBIR I

Information

• Research Project
• 6325674

• ApplicationId

  6325674

• Core Project Number

  N43AA001002

• Full Project Number

  N43AA001002-000

• Serial Number

  1002

• FOA Number

• Sub Project Id

• Project Start Date

  6/30/2000 - 24 years ago

• Project End Date

  -

• Program Officer Name

• Budget Start Date

  6/30/2000 - 24 years ago

• Budget End Date

  9/30/2000 - 24 years ago

• Fiscal Year

  2000

• Support Year

• Suffix

• Award Notice Date

  -

Organizations

• ALKERMES, INC

This proposal will develop a sustained release formulation of naltrexone to be given subcutaneously. The formulation will deliver therapeutic concentrations of naltrexone for 30 days. Pharmacokinetic testing will be conducted in rats and later in primates while local irritability testing will be carried out in rabbits. Subsequently, the investigators plan to proceed rapidly into clinical trials to demonstrate safety and efficacy of the formulation with the goal of achieving regulatory approval to market the new product for the treatment of alcoholic patients.

IC Name

• Activity

  N43

• Administering IC

  AA

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

  99193

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  273

• Ed Inst. Type

• Funding ICs

  NIAAA:99193\

• Funding Mechanism

• Study Section

• Study Section Name

• Organization Name

  ALKERMES, INC.

• Organization Department

• Organization DUNS

  185481132

• Organization City

  WALTHAM

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  024511420

• Organization District

  UNITED STATES