Claims
- 1. A synthetic peptide having the following amino acid sequence: asn-a-thr-leu-b-gln-ile-c-d-lys-leu-arg-glu-gln-phe-gly-asn-asn-lys; where a is asn or ala; b is lys or glu; c is asp, val or ala; and d is ser or lys.
- 2. A synthetic peptide having the following amino acid sequence: thr-arg-pro-asn-asn-asn-thr-arg-lys-ser-ile-e-ile-f-f-gly-pro-gly; where e is arg or tyr; and f is either gln, arg, or omitted.
- 3. A synthetic peptide having the following amino acid sequence: lys-arg-arg-val-val-gln-arg-glu-lys-arg-ala-val-gly-g-ile-gly-ala-h-phe; where g is val or omitted; and h is leu or met.
- 4. A synthetic peptide having the following amino acid sequence: x-asp-arg-pro-i-gly-ile-glu-glu-glu-j-gly-glu-arg-asp-arg-asp-arg-ser; where x is leu-pro-ile-pro-arg-gly-pro or omitted; i is glu or asp; and j is gly or asp.
- 5. A synthetic peptide having the following amino acid sequence: ala-ile-k-his-ile-l-arg-arg-ile-arg-gln-gly-leu-glu-arg; where k is arg or leu; and l is pro or his.
- 6. An immunogenic composition comprising a carrier conjugated to a synthetic peptide selected from the group consisting of the following amino acid sequences:
- asp-arg-pro-glu-gly-ile-glu-glu-glu-gly-gly-glu-arg-asp-arg-asp-arg-ser;
- asp-arg-pro-glu-gly-ile-glu-glu-glu-asp-gly-glu-arg-asp-arg-asp-arg-ser; and
- asp-arg-pro-asp-gly-ile-glu-glu-glu-gly-gly-glu-arg-asp-arg-asp-arg-ser.
- 7. An antibody raised against a synthetic peptide as claimed in any one of claims 1-5.
- 8. A method for the detection of antibodies against the viral causative agents of AIDS comprising contacting a synthetic peptide as claimed in any one of claims 1-5 with a sample suspected of containing said antibodies and using the binding affinity of the synthetic peptide to detect said antibodies.
Parent Case Info
This application is a continuation of co-pending application Ser. No. 06/790,830, filed on Oct. 24, 1985.
STATEMENT OF GOVERNMENT INTEREST
The invention herein was made with Government support and the Government has certain rights in the invention.
US Referenced Citations (7)
Non-Patent Literature Citations (5)
Entry |
Ratner et al., Nature, 312 (1/24/85) 277-83. |
Crowl et al., Cell, 41 (7/1985) 979-86. |
Allan et al., Science, 288 (5/31/85) 1091-4. |
Schupbach et al., New. Eng. J. Med, 312 (1/31/85) 265-70. |
Montagnier et al, Virology, 144 (1985) 283-9. |
Continuations (2)
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Number |
Date |
Country |
Parent |
203609 |
Jun 1988 |
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Parent |
790830 |
Oct 1985 |
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