Claims
- 1. A syringe mixing and delivery system comprising:
- a first barrel having an open end and an opposite delivery end defining a delivery passage;
- a reciprocable stopper sealingly disposed in said first barrel to define a first chamber between said delivery passage and said reciprocable stopper for containing a first constituent in said first chamber;
- a second barrel that is sized to be disposed in said first barrel and that has an open end and an opposite discharge end defining a discharge passage;
- a slidable plunger sealingly disposed within said second barrel to define a second chamber between said discharge passage and said slidable plunger for containing a liquid second constituent in said second chamber; and
- fluid transfer connector means for operatively connecting said second barrel with said reciprocable stopper to permit flow of said liquid second constituent through said stopper from said second chamber to said first chamber to mix with said first constituent when said second barrel discharge end and plunger are moved closer together whereby subsequent movement of said second barrel and reciprocable stopper together toward said delivery passage of said first barrel expresses the mixed constituents out of said first chamber through said delivery passage.
- 2. The system in accordance with claim 1 wherein said fluid transfer connector means includes:
- (1) a hollow piercing needle carried by said second barrel in communication with said discharge passage; and
- (2) a portion of said reciprocable stopper being fully penetratable by said piercing needle.
- 3. The system in accordance with claim 1 wherein said fluid transfer connector means includes:
- (1) a conduit extending through said reciprocable stopper and having an inlet end and an outlet end;
- (2) a flapper valve member in said reciprocable stopper adjacent said conduit outlet end and biased to a normally closed position occluding said conduit to said conduit outlet end;
- (3) a flange on said conduit inlet end; and
- (4) a thread form on said second barrel for being threadingly engaged by said flange whereby fluid communication is established between said discharge passage and said conduit.
- 4. The system in accordance with claim 1 wherein said fluid transfer connector means includes:
- (1) a resilient portion defined in said reciprocable stopper and which has at least one longitudinal slit therethrough defining resilient lips which are biased to a normally closed position and which can open toward said delivery passage into said first chamber;
- (2) an enlarged receiving cavity in said reciprocable stopper resilient portion adjacent said resilient lips and a smaller entrance passage in said reciprocable stopper opening into said enlarged cavity whereby a retention shoulder is defined at one end of said enlarged cavity around said smaller entrance passage; and
- (3) an enlarged head at said discharge passage of said second barrel for being received in said enlarged receiving cavity of said reciprocable stopper and a smaller neck at said discharge passage of said second barrel for being received in said entrance passage of said reciprocable stopper whereby said discharge passage of said second barrel is normally occluded by said biased closed resilient lips of said reciprocable stopper.
- 5. The system in accordance with claim 1 wherein said fluid transfer connector means includes (a) connecting means for connecting said second barrel with said reciprocable stopper, and (b) fluid communicating means permitting flow of said liquid second constituent through said stopper from said second chamber to said first chamber, said fluid communicating means comprising:
- a first fluid connector associated with said reciprocable stopper in said first barrel;
- a cooperating second fluid connector associated with said discharge passage of said second barrel; and
- a fluid passageway from said first fluid connector to said first chamber including a normally closed one way flow valve.
- 6. The system in accordance with claim 5 wherein
- said fluid passageway is defined at least in part through said reciprocable stopper; and
- said one way flow valve is integral with said reciprocal stopper.
- 7. The system in accordance with claim 6 wherein
- said first fluid connector includes a luer socket mounted in said reciprocable stopper in fluid communication with said one way flow valve;
- said second flow connector includes a luer nozzle at said discharge passage of said second barrel; and
- said connecting means comprises a thread form on said second barrel proximate said luer nozzle and a radial flange on said luer socket, said radial flange being threadably engageable with said second barrel thread form for connecting said luer nozzle to said luer socket.
- 8. The system in accordance with claim 5 in which
- said first fluid connector is a support member having a luer socket that is in fluid communication with said fluid passageway;
- said cooperating second fluid connector is a luer nozzle at said discharge end of said second barrel for being placed in fluid communication with said support member luer socket; and
- said connecting means comprises a friction fit of said second barrel luer nozzle in said support member luer socket.
- 9. The system in accordance with claim 8 in which said connecting means further comprises a thread form defined in said support member proximate said luer socket and a radial flange on said second barrel for threadingly engaging said support member thread form.
- 10. The system in accordance with claim 1 wherein
- said plunger includes a slidable piston and a shank mounted to said slidable piston; and
- said system further includes
- a first removable closure occluding said first barrel delivery passage; and
- a second removable closure occluding said second barrel discharge passage.
- 11. A prefilled syringe system for separately storing a first constituent and a liquid second constituent and for subsequently mixing and dispensing a mixture of said constituents, said system comprising:
- a first barrel having an open end and an opposite delivery end defining a delivery passage;
- a first removable closure sealingly occluding said delivery passage;
- a reciprocable stopper sealingly disposed in said first barrel to define a first chamber between said delivery passage and said reciprocable stopper for containing a first constituent in said first chamber;
- a second barrel that is sized to be disposed in said first barrel and that has an open end and a discharge end defining a discharge passage;
- a second removable closure occluding said discharge passage;
- a slidable plunger sealingly disposed within said second barrel to define a second chamber between said discharge passage and said slidable plunger for containing a liquid second constituent in said second chamber; and
- coupling means for operatively coupling said second barrel to said reciprocable stopper in said first barrel when said second barrel is telescopically positioned in said open end of said first barrel so that said liquid second constituent can be caused to flow through said stopper from said second chamber to said first chamber to mix with said first constituent by movement of said second barrel discharge end and plunger closer together whereby subsequent movement of said second barrel and reciprocable stopper together toward said delivery passage of said first barrel expresses the mixed constituents out of said first chamber through said delivery passage.
- 12. The prefilled syringe system in accordance with claim 11 in which said coupling means includes:
- (1) a hollow piercing needle carried by said second barrel at said discharge passage and in fluid communication with said second chamber, and
- (2) a portion of said reciprocable stopper being fully penetratable by, and couplingly engageable by, said piercing needle upon removal of said second removable closure from said discharge passage of said second barrel.
- 13. The prefilled syringe system in accordance with claim 11 wherein said coupling means comprises
- (1) fluid communicating means for communicating fluid from said second chamber to said first chamber, and
- (2) connecting means for connecting said second barrel with said reciprocable stopper.
- 14. The prefilled syringe system in accordance with claim 13 in which said fluid communicating means includes
- (1) a conduit through said reciprocable stopper and having an inlet end and an outlet end;
- (2) a valve member in said reciprocable stopper adjacent said conduit outlet end and biased to a normally closed position occluding said conduit outlet end;
- (3) a first fluid connector on said conduit inlet end; and
- (4) a cooperating second fluid connector at said discharge passage of said second barrel for engaging said first fluid connector on said conduit inlet end upon removal of said second removable closure whereby fluid communication is established between said discharge passage and said conduit.
- 15. The prefilled syringe system in accordance with claim 14 wherein said connecting means includes a threadable flange on said first fluid connector at said conduit inlet end and a thread form on said second barrel on said cooperating second fluid connector at said discharge passage of said second barrel for being threadingly engaged by said threadable flange.
- 16. The prefilled syringe in accordance with claim 13 wherein
- said fluid communicating means includes a resilient portion defined in said reciprocable stopper which has at least one longitudinal slit therethrough defining resilient lips which are biased to a normally closed position and which can open toward said delivery passage into said first chamber; and
- said connecting means includes:
- (1) an enlarged receiving cavity in said reciprocable stopper resilient portion adjacent said resilient lips and a smaller entrance passage in said reciprocable stopper opening into said enlarged cavity whereby a retention shoulder is defined at one end of said enlarged cavity around said entrance passage; and
- (2) an enlarged head at said discharge passage of said second barrel received in said enlarged receiving cavity of said reciprocable stopper upon removal of said second removable closure and a smaller neck at said discharge passage of said second barrel for being received in said entrance passage of said reciprocable stopper whereby said discharge passage of said second barrel is normally occluded by said resilient lips of said reciprocable stopper in the biased closed position.
- 17. The prefilled syringe system in accordance with claim 11 wherein said coupling means includes
- (a) a connecting means for connecting said second barrel with said reciprocable stopper, and
- (b) a fluid communicating means for accommodating transfer of fluid from said second chamber to said first chamber, said fluid communicating means comprising:
- a first fluid connector associated with said reciprocable stopper;
- a cooperating second fluid connector associated with said discharge passage of said second barrel; and
- an openable and closeable fluid passageway from said first fluid connector in said reciprocable stopper to said first chamber of said first barrel.
- 18. The prefilled syringe system in accordance with claim 17 wherein
- said first fluid connector includes a stopper support member having a luer socket that is in fluid communication with said fluid passageway; and
- said cooperating second fluid connector includes a luer nozzle at said discharge passage of said second barrel for being placed in fluid communication with said support member.
- 19. The prefilled system in accordance with claim 18 wherein said fluid communicating means further comprises a resilient central portion defined in said reciprocable stopper which has at least one longitudinal slit therethrough defining resilient lips which are biased to a normally closed position and which can open toward said delivery passage into said first chamber to define at least a portion of said fluid passageway.
- 20. The prefilled syringe system in accordance with claim 19 wherein said connecting means includes
- an enlarged receiving cavity in said reciprocable stopper central portion adjacent said resilient lips and a smaller entrance passage in said reciprocable stopper opening into said enlarged cavity whereby a retention shoulder is defined at one end of said enlarged cavity around said smaller entrance passage;
- an enlarged head that is defined by said support member and that is received in said enlarged receiving cavity of said reciprocable stopper; and
- a smaller neck that is defined by said support member and that is received in said entrance passage of said reciprocable stopper wherein said fluid passageway extends through said enlarged head and smaller neck from said luer socket through said longitudinal slit whereby said discharge passage of said second barrel is normally occluded by said biased closed resilient lips of said reciprocable stopper.
Parent Case Info
This application is a continuation of Ser. No. 08/722,603, filed Sep. 27, 1996 now abandoned which is a Continuation In Part of Ser. No. 08/408,463, filed Mar. 22, 1995.
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Continuations (1)
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Number |
Date |
Country |
Parent |
722603 |
Sep 1996 |
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Continuation in Parts (1)
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Number |
Date |
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Parent |
408463 |
Mar 1995 |
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