The present invention relates generally to radiographic indexing of a radiation therapy treatment table, and more particularly to a system and method for calibrating and positioning a radiation therapy treatment table with a high degree of precision and accuracy through the use of radiographic indexing markers embedded in the treatment table.
Radiation therapy treatment tables are conventionally and typically used to hold the patient in a substantially rigid position, while the patient is being exposed to a radiation source. Typically, the radiation source is mounted above the treatment table and movable around the table so that the patient can be exposed to radiation from all possible angles, and allowing for purposefully directed radiation at the precise tumor site needed to destroy the tumor and minimize the exposure to healthy tissue.
In radiation therapy treatment of patients, it is imperative that the patient be held in a correct position relative to the radiotherapy machine in order to attain the expected treatment result without damaging healthy tissue outside of the treatment area. A need exists for a patient positioning system that is used to accurately and reproducibly position a patient on a table for radiation therapy, diagnostic imaging, surgery, and other medical procedures.
The present invention provides a system and method for calibrating and positioning a radiation therapy treatment table with a high degree of precision and accuracy. The present invention provides for embedding or inlaying material for radiographic referencing into the patient treatment table of a radiation therapy system. The material is preferably a radiological marker or indexing material that has a density different from density of the table material, or a radio-frequency or magnetic contrasting matter, something that the imaging system and detector of the radiation therapy system can detect, so that when scanned, with or without a patient or phantom on the table, the precise location of the patient treatment table in the x, y and z planes is known. The material may also have the ability to be visually seen by the technician, doctor, physicist or other health care provider conducting the procedure. This is important so that the table may be reconstructed, alone or with a phantom on it, by the radiation therapy system software, providing a very good indication of where the table top is prior to treatment.
The present invention provides for calibrating the location and position of the treatment table, and also for accurately positioning a patient on the treatment table. For example, the present invention is capable of providing methods for aligning the table with the bore, detecting the scan plane, determining the slice-sensitivity profile for computed tomography (CT) and other modality images, and aligning lasers with the virtual scan plane.
The present invention also provides methods to verify quality assurance (QA) and patient procedures. For example, the present invention is capable of providing methods for verifying the table speed and/or position and table-bore collision avoidance.
In addition to the calibration and QA uses described above, the present invention may also be used for: (a) improving or simplifying the setup of the patient on the table; (b) improving or simplifying the placement of patient fixation devices on the table; and (c) identifying coordinate transformations between patient space and fixation-device space. For example, the radiation therapy system could convert a set of patient adjustments detected in a CT image to proper translations or rotations on a given fixation device.
As mentioned above, the present invention comprises a patient treatment table having a radiological marker or indexing matrix embedded or inlaid into the patient treatment table of a radiation therapy system. The inlaid radiological marker or indexing matrix may be placed and spaced in any configuration in the table. The markers can be permanent or replaceable. The radiological markers or indexing matrix may be actual material or voids that provide contrasting densities in the treatment table that are detectable. The present invention includes various styles and forms of radiological markers and in various configurations.
The marker or indexing matrix is comprised of contrasting high or low density material in the form of solids (e.g. wire, pellets, balls, paste, etc.), liquids (e.g. column of water, bubble-level, etc.), disjoint solids (e.g. strings of marker beads, etc.) that are inlaid into or fixed onto the sides, top or bottom of the patient treatment table. These density markers can either be actual objects or the absence or objects (e.g. voids).
In one embodiment, the markers are protrusions from the table, allowing for patient fixation devices to be connected to the protrusions. In another embodiment, the markers are flush with the sides or surfaces of the table. In yet another embodiment, the markers are indentations or grooves in the table. In still another embodiment, the markers are embedded at a depth into the table.
The markers may be individual markers or may be arranged in sets of two or three, or more, and potentially utilize the sides and/or surfaces of the treatment table. The markers may also be permanently fixed or removable from the treatment table, to minimize interference with dose delivery. The markers may also be interchangeable with different sets or subsets utilized for different objectives.
In another embodiment, the markers are magnetic, or include magnets or sensors that are used for positioning patients and/or fixation devices on the treatment table.
In another embodiment, the markers emit radio frequency (RF) signals which are detected using RF sensitive detection devices. The markers of the present invention may also be RF detectors for detecting RF signals.
In yet another embodiment, the markers include lasers that can be used for any of the above purposes, including the positioning of patients and/or fixation devices on the table, avoidance of table collisions, system setup and calibration, etc. The markers, including lasers, may send and/or receive signals with other fixtures in the room to detect changes in table height or deformations in the table, such as sagging. This information can be used to automatically, semi-automatically, or manually adjust the table position before or during treatment procedures.
The markers may also be used for calibration and verification of table speed, table position and of the virtual isocenter. Treatment accuracy is maintained by aligning the linear accelerator's isocenter to a precise point within the patient. The isocenter is a single reference point in the x, y and z planes of the Cartesian coordinate system which serves to orient the radiation beams to the proper coordinates of the slices of the tumor in the patient.
In further embodiments, the present invention comprises radiographic plugs, contrast inserts or resolution inserts that are inserted into openings in the patient treatment table. In an alternative embodiment, the contrast inserts or resolution inserts could also be embedded or molded into the table. The plugs or inserts are preferably used for calibrating the imaging system or dose delivery, and positioning the patient on the table.
Various other features, objects, and advantages of the invention will be made apparent to those skilled in the art from the accompanying drawings and detailed description thereof.
Referring now to the drawings,
A rotating gantry 24, coaxial with the bore 18 and positioned within the housing 20, supports an x-ray source 26 and a high energy radiation source 28 on its inner surface. The x-ray source 26 and the radiation source 28 rotate with the gantry 24 about a center of rotation near the top of the patient table 12 when the table top 14 is positioned within the bore 18.
The x-ray source 26 is collimated to produce a fan beam 30 lying generally within the x-y plane and crossing the bore 18 and thus the table top 14 when the table top is positioned within the bore 18. The fan beam 30 diverges about a central axis whose angle is controlled by the position of the gantry 24. After exiting the table top 14, the fan beam 30 is received by a linear array detector 32 positioned diametrically across from the x-ray source 26. Thus, the rotating gantry 24 permits fan beam radiographic projections of a patient on the table top 14 to be acquired at a variety of angles about the patient during the treatment process.
The radiation source 28 is mounted so as to project a fan beam of high energy radiation 34, similar to the fan beam 30, but crossing fan beam 30 at right angles so as to be received on the other side of the gantry 24 by a radiation detector and stop 36. Therefore, the x-ray can be taken of a region prior to application of radiation. The radiation source 28 has a collimator 38 mounted in front of it to divide the fan beam of high energy radiation 34 into multiple adjacent rays whose intensity may be individually controlled to adjust the fluence of radiation. The location of the radiation source 28 and x-ray source 26 are precisely characterized so that images obtained from the x-ray source 26 may be used to aim the radiation source 28.
The radiation therapy machine 10 further includes a computer 40 having a display screen 42 and user entry input devices 44, well known in the art, that is connected to the radiation therapy machine 10 to control motion of the table 12 and to coordinate operation of the gantry 24 together with the radiation source 28 and x-ray source 26 and to collect data from the linear array detector 32 during a scan of a patient according to methods well known in the art.
The present invention provides radiographic indexing marker embedded or inlaid in the patient treatment table. The radiographic indexing markers are preferably used for positional calibration of the patient treatment table. The present invention comprises a patient treatment table having at least one radiological marker or indexing matrix embedded or inlaid into the patient treatment table of a radiation therapy system. The radiological marker or indexing matrix may be placed and spaced in any configuration in the table. The inlaid radiological marker or indexing matrix may be actual material or voids that provide contrasting densities in the treatment table that are detectable. The marker or indexing matrix is comprised of contrasting high or low density material in the form of solids (e.g. wire, pellets, balls, paste, etc.), liquids (e.g. column of water, bubble-level, etc.), disjoint-solids (e.g. strings of marker beads, etc.) that are inlaid into or fixed onto the sides, top or bottom of the patient treatment table. These density markers can either be actual objects or the absence or objects (e.g. voids). The present invention includes various styles and forms of radiological markers and in various configurations.
In another embodiment, the markers are protrusions from the table, allowing for patient fixation devices to be connected to the protrusions. In another embodiment, the markers are flush with the sides or surfaces of the table. In yet another embodiment, the markers are indentations or grooves in the table. In still another embodiment, the markers are embedded at a depth into the table. The markers may be individual markers or may be arranged in sets of two or three, or more, and potentially utilize the sides and/or surfaces of the treatment table. The markers may also be permanently fixed or removable from the treatment table, to minimize interference with dose delivery. The markers may also be interchangeable with different sets or subsets utilized for different objectives.
In another embodiment, the markers are magnetic, or include magnets or sensors that are used for positioning patients and/or fixation devices on the treatment table. In still another embodiment, the markers emit radio frequency (RF) signals which are detected using RF sensitive detection devices. The markers of the present invention may also be RF detectors for detecting RF signals.
In yet another embodiment, the markers include lasers that can be used for any of the above purposes, including the positioning of patients and/or fixation devices on the table, avoidance of table collisions, system setup and calibration, etc. The markers, including lasers, may send and/or receive signals with other fixtures in the room to detect changes in table height or deformations in the table, such as sagging. This information can be used to automatically, semi-automatically, or manually adjust the table position before or during treatment procedures.
The markers can also include TLDs, MOSFETs, diodes, or other dosimetric devices used to measure dose during the treatment or scan procedures. Use of these devices can be integrated into QA, dose reconstruction, treatment planning, or other related applications.
The markers may also be used for calibration and verification of table speed, table position and of the virtual isocenter. Treatment accuracy is maintained by aligning the linear accelerator's isocenter to a precise point within the patient. The isocenter is a single reference point in the x-y-z planes which serves to orient the radiation beams to the proper coordinates of the slices of the tumor in the patient.
In addition to the embodiments shown, the present invention comprises radiographic plugs that are inserted into the table that are used for calibrating the imaging system. The plugs would preferably have a density different than bone, tissue or water. The radiographic plugs would preferably be inserted into a row of cylindrical holes at the ends of the table.
The plugs would generally be used to calibrate the imaging system. You would take an image of the table and make sure that you see the plugs where you expect to see them. The plugs are preferably used for density or imaging calibration. The plugs may be the same or a different density from the table material. The plugs are generally available from such manufacturers as Standard Imaging or Gammex.
In another embodiment, either contrast inserts or resolution inserts would be inserted into the openings described above. In an alternative embodiment, the contrast inserts or resolution inserts could also be embedded or molded into the table. The resolution inserts would preferably be a set of wires or openings based on some even or uneven spacing. These inserts would be used for calibrating the imaging system, and possibly positioning of the patient on the table.
In another embodiment, the present invention comprises a substantially flat member that includes radiographic indexing markers and is placed on and/or attaches to the patient treatment table for positional calibration of the treatment table.
The markers of the present invention may interact with markers in or on the patient, or characteristics of the patient, to determine the patient position relative to the couch. This includes, but is not limited to, magnetic, RF, laser, and/or light signals.
While the invention has been described with reference to preferred embodiments, those skilled in the art will appreciate that certain substitutions, alterations and omissions may be made to the embodiments without departing from the spirit of the invention. Accordingly, the foregoing description is meant to be exemplary only, and should not limit the scope of the invention as set forth in the following claims.
This application is a continuation of and claims priority to U.S. patent application Ser. No. 12/651,680, filed on Jan. 4, 2010, which is a continuation of U.S. patent application Ser. No. 10/577,567, filed on Mar. 23, 2007, which is a national stage filing under 35 U.S.C. §371 of International Application No. PCT/US04/36416, filed on Oct. 29, 2004, and claims priority to U.S. Provisional Patent Application No. 60/515,481, filed on Oct. 29, 2003. The entire contents of each of these applications are incorporated herein by reference.
Number | Date | Country | |
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60515481 | Oct 2003 | US |
Number | Date | Country | |
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Parent | 12651680 | Jan 2010 | US |
Child | 13545545 | US | |
Parent | 10577567 | Mar 2007 | US |
Child | 12651680 | US |