The present application claims the benefit of the filing date of China patent application no. CN 202010979058.0, filed on Sep. 17, 2020, the contents of which are incorporated herein by reference in their entirety.
The disclosure relates to the field of magnetic resonance imaging (MRI) and, in particular, to techniques related to saturation band MRI scanning.
With MRI, a radio frequency (RF) pulse at a specific frequency is applied to a human body in a static magnetic field, so that hydrogen protons in the human body are excited to generate magnetic resonance (MR). After the pulse is stopped, an MR signal is generated during relaxation of the protons, and an MR image is produced through the processes of MR signal reception, spatial encoding, image reconstruction, etc.
During the imaging process, after the RF excitation the slice is first selected through the Z-direction gradient, i.e., a slice to be imaged is selected; then the magnetic field in the Y direction is turned on, so that the magnetic moment will precess at different speeds at different Y positions; the Y gradient is then turned off, so that the magnetic moment will precess at the same speed again at all the positions, but the different precession speeds cause different phase deviations at different Y positions; the process is called phase encoding. Next, the gradient in the X direction is turned on, and the magnetic moment will precess at different speeds at different X positions; the process is called frequency encoding. At this point, through phase encoding and frequency encoding, each position of a 2D image can be determined. The signal collected by the receiving coil is a k-space signal, and an image can be obtained through Fourier transform. Then, another round of slice selection can be completed through the Z-direction gradient, and a 3D MRI image can be obtained by repeating the above process.
Because the hydrogen protons in adipose tissue and other tissues in the human body are in different molecular environments, their resonance frequencies are different; when the hydrogen protons in fat and other tissues are simultaneously excited by radio frequency pulses, they will have different relaxation times. When signals at different echo times are collected, fat tissue and non-fat tissue show different signal intensities. Taking advantage of the above characteristics of different tissues in the human body, a variety of pulse sequences have been developed to suppress fat signals.
Fat saturation (FATSAT) is a radio frequency selective fat suppression method. The basic principle is to use the small difference in the resonance frequency between fat and water, and selectively place fat into saturation by adjusting the frequency and bandwidth of the excitation pulse so that fat protons will not generate a signal, and an imaging containing only the water proton signal is obtained. When a FATSAT sequence begins, the selected slice is excited by a 90° RF pulse at the same resonance frequency as that of fat (saturation pulse), to flip the macroscopic magnetization vector of fat to the transverse (X-Y) plane; after the excitation pulse, a spoiling (phase destroying) gradient pulse is immediately applied, to destroy the consistency of fat signal phase. The imaging pulse is applied immediately afterwards. Since the time between echo signal acquisition and the saturation pulse is very short (<100 ms), fat protons do not have enough time to recover the longitudinal magnetization vector, and no signal is generated, thus achieving the purpose of fat suppression.
In MRI, chemical shift is a very important phenomenon, as when the static magnetic field is not uniform in intensity, the precession frequencies of fat and water will be affected by local magnetic fields and deviations will occur. Non-uniformity of the magnetic field may occur in regions with significant changes in anatomical structure morphology.
The chemical shift is more significant in high-field systems (for example, a 3 T system). In order to prevent negative impacts of a regional saturation band and the possibility of exciting the region of interest by mistake, the current solution for 3 T systems is to use a hard-coding method to implicitly reduce the width of saturation bands. Specifically, the width of a saturation band is implicitly reduced to 85% of that actually required by the user. With this method, it is assumed that within the 15% reduced area, where the worst-case chemical shift occurs, the saturation pulse will not affect the region of interest.
With the method of implicitly reducing the width of the saturation band, wrong excitation of the region of interest can be prevented, but the reduction of the saturation band will reduce the saturation region, resulting in the suppressed region being narrower than required and a suppression effect being not as expected.
In view of this, the embodiments of the present disclosure provide a method, device, and an MRI system for saturation band MRI scanning, which prevent the wrong excitation of the region of interest by the saturation pulse without changing the width of the saturation band.
The technical solution of the embodiments of the present disclosure may be implemented in the following manner:
A method for saturation band MRI scanning, comprising:
Obtaining the position of a saturation band of the saturation band MRI;
Obtaining the position of a saturation band of the saturation band MRI comprises: determining the central point of the saturation band of the saturation band MRI;
At the same time as the slice selection gradient is applied on the saturation band in the direction of the slice selection gradient, the method further comprises:
A device for saturation band MRI scanning, comprising:
Obtaining, by the direction determining module or circuitry, the position of a saturation band of the saturation band MRI comprises: determining the central point of the saturation band of the saturation band MRI;
The device further comprises: an RF control module or circuitry (e.g. processing circuitry that may include hardware such as one or more processors, software such as executable instructions, or combinations thereof) for controlling the application of radio frequency saturation pulses, used to apply a radio frequency saturation pulse on the slice selected by the slice selection gradient.
A device for saturation band MRI scanning, comprising: a memory and a processor that can access the memory, wherein the memory stores an instruction, which, when executed by the processor, causes the processor to execute the steps of the method described in any of the above paragraphs.
An MRI system, comprising the devices for saturation band MRI scanning described in any of the above paragraphs.
In the embodiments of the present disclosure, when the slice selection gradient is in the same direction as that from the saturation band to the region of interest, the sign of the applied slice selection gradient is positive and the intensity of the corresponding magnetic field gradually increases; otherwise, the sign of the applied slice selection gradient is negative and the intensity of the corresponding magnetic field gradually decreases, so that the chemical shift caused by the slice selection gradient in the saturation band is always away from the region of interest, and wrong excitation of the region of interest by the saturation pulse can be prevented without changing the width of the saturation band.
As further discussed herein, the disclosure relates to techniques for saturation band MRI scanning. The techniques include obtaining the position of a saturation band of the saturation band MRI; obtaining the position of the region of interest to be imaged; taking the direction from the saturation band to the region of interest as a first direction; determining the direction of the slice selection gradient; starting saturation band MRI scanning. The slice selection gradient is applied on the saturation band in the direction of the slice selection gradient and, when the direction of the slice selection gradient is the same as the first direction, the gradient sign of the applied slice selection gradient is positive and the intensity of the corresponding magnetic field gradually increases. When the direction of the slice selection gradient is opposite to the first direction, the gradient sign of the applied slice selection gradient is negative and the intensity of the corresponding magnetic field gradually decreases. The chemical shift caused by the slice selection gradient in the saturation band is away from the region of interest so that wrong excitation of the region of interest by the saturation pulse can be prevented without changing the width of the saturation band.
The preferred embodiments of the present disclosure will be described in detail below with reference to the drawings, so that those skilled in the art will better understand the above and other features and advantages of the present disclosure. In the drawings:
In the drawings, the following reference numerals are used:
The following example embodiments will further illustrate the present disclosure in detail in order to clarify its purpose, technical solution and advantages.
Step 301: obtaining the position of a saturation band of the saturation band MRI, obtaining the position of the region of interest to be imaged, and taking the direction from the saturation band to the region of interest as a first direction.
Step 302: determining a direction of the slice selection gradient.
The saturation band is perpendicular to the region of interest, and the slice selection gradient is perpendicular to the saturation band. Then, there are two directions for the slice selection gradient: one is the same as the direction from the saturation band to the region of interest, and the other is opposite to the direction from the saturation band to the region of interest.
Step 303: start saturation band MRI scanning, wherein the slice selection gradient is applied on the saturation band in the direction of the slice selection gradient and, when the direction of the slice selection gradient is the same as the first direction, the gradient sign of the applied slice selection gradient is positive and the intensity of the corresponding magnetic field gradually increases and, when the direction of the slice selection gradient is opposite to the first direction, the gradient sign of the applied slice selection gradient is negative and the intensity of the corresponding magnetic field gradually decreases.
At the same time as the slice to be excited is selected by the slice selection gradient, a radio frequency saturation pulse is applied on the slice selected.
In the above embodiment, when the slice selection gradient is in the same direction as that from the saturation band to the region of interest, the sign of the applied slice selection gradient is positive and the intensity of the corresponding magnetic field gradually increases; otherwise, the sign of the applied slice selection gradient is negative and the intensity of the corresponding magnetic field gradually decreases, so that the chemical shift caused by the slice selection gradient in the saturation band is always away from the region of interest, and wrong excitation of the region of interest by the saturation pulse can be prevented without changing the width of the saturation band.
In an alternative embodiment, in step 301 obtaining the position of a saturation band of the saturation band MRI comprises: determining the central point of the saturation band of the saturation band MRI;
Obtaining the position of the region of interest to be imaged comprises: determining the central point of the field of view (FOV) of imaging;
Taking the direction from the saturation band to the region of interest as a first direction comprises: taking the direction from the central point of the saturation band to the central point of the FOV as a first direction.
Through the above embodiment, it is ensured that the chemical shift caused by the slice selection gradient in the saturation band is always away from the region of interest.
It can be seen from
Therefore, to keep the chemical shift of the saturation band away from the region of interest, a relationship shown in Table 1 can be obtained:
In
In
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In
Verification of the present disclosure by simulated experiments is described below.
The top and at the bottom grids associated with
The two grids associated with
The two grids associated with
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It can be seen that, when there are saturation bands on both sides of the FOV, when the conventional hard-coding method is used, the chemical shifts of the saturation bands on both sides are in the same direction; while with the present disclosure, slice selection gradients of different signs and the intensities of the magnetic fields can be applied on the saturation bands on the two sides, so that chemical shifts of the two saturation bands are in the different directions, making it possible to completely prevent wrong excitation of the region of interest by the saturation pulse.
It should be noted that there are small white characters in some areas of
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It should be noted that there are small white characters in some areas of
A direction determining module or circuitry (e.g. processing circuitry that may include hardware such as one or more processors, software such as executable instructions, or combinations thereof) 91, used to obtain the position of a saturation band of the saturation band MRI, obtain the position of the region of interest to be imaged, take the direction from the saturation band to the region of interest as a first direction; and determine the direction of the slice selection gradient;
A slice selection gradient control module or circuitry (e.g. processing circuitry that may include hardware such as one or more processors, software such as executable instructions, or combinations thereof) 92 for controlling the application of the slice selection gradient, used to, when the saturation band MRI scanning starts, apply the slice selection gradient on the saturation band in the direction of the slice selection gradient, wherein, when the direction of the slice selection gradient is the same as the first direction, the gradient sign of the applied slice selection gradient is positive and the intensity of the corresponding magnetic field gradually increases, and when the direction of the slice selection gradient is opposite to the first direction, the gradient sign of the applied slice selection gradient is negative and the intensity of the corresponding magnetic field gradually decreases.
In an alternative embodiment, obtaining, by the direction determining module 91, the position of a saturation band of the saturation band MRI comprises: determining the central point of the saturation band of the saturation band MRI;
Determining, by the direction determining module 91, the position of the region of interest to be imaged comprises: determining the central point of the field of view (FOV) of imaging;
Taking, by the direction determining module 91, the direction from the saturation band to the region of interest as a first direction comprises: taking the direction from the central point of the saturation band to the central point of the FOV as a first direction.
In an alternative embodiment, the device further comprises: an RF control module or circuitry (e.g. processing circuitry that may include hardware such as one or more processors, software such as executable instructions, or combinations thereof) for controlling the application of radio frequency saturation pulses, used to apply a radio frequency saturation pulse on the slice selected by the slice selection gradient.
The embodiments of the present disclosure also provide an MRI system, comprising the devices for saturation band MRI scanning described in any of the above paragraphs.
It should be noted that, since the present disclosure determines the sign of the slice selection gradient and the magnetic field intensity by comparing the direction of the slice selection gradient with the direction from the saturation band to the region of interest, the present disclosure does not need to consider whether the saturation band is symmetrical or not, i.e., the present disclosure is not only suitable for symmetrical saturation bands, but also for asymmetrical saturation bands.
The above are only the preferred embodiments of the present disclosure, and are not intended to limit the present disclosure. Any modification, equivalent replacement and improvement made without departing from the motivation and principle of the present disclosure shall be included in its scope
Number | Date | Country | Kind |
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202010979058.0 | Sep 2020 | CN | national |
Number | Name | Date | Kind |
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5510713 | Bernstein | Apr 1996 | A |
20120226141 | Shinoda | Sep 2012 | A1 |
Number | Date | Country | |
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20220082645 A1 | Mar 2022 | US |