System for syringe engagement to an injector

Information

  • Patent Grant
  • 10806852
  • Patent Number
    10,806,852
  • Date Filed
    Wednesday, March 18, 2015
    9 years ago
  • Date Issued
    Tuesday, October 20, 2020
    3 years ago
Abstract
An injector system for injecting fluid includes a syringe and an injector. The syringe includes a body and a plunger movably disposed within the body. The plunger has at least one flexible leg extending toward the rearward end of the body. The injector has a housing with a front plate, a drive member at least partially disposed within the housing and operable to engage the plunger, and a syringe release assembly operable to release the syringe. The syringe assembly includes a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing and a plunger release tube surrounding at least a portion of the drive member. The plunger release tube has a first end rotationally engaged with the syringe release gear. Rotation of the syringe release assembly releases the at least one flexible leg from the drive member.
Description
BACKGROUND

Field


This application relates to medical injectors and syringes, syringe interfaces, and syringe plungers for use therewith. More particularly, the present application relates to front-loading medical injectors and syringes, syringe interfaces, and syringe plungers for use with new or existing medical injectors such that the syringe is mountable upon and removable from the injectors by a syringe latch.


Description of Related Art


Medical injectors and syringes for injecting contrast media into a patient for imaging biological structures are known in the art. For example, with reference to FIG. 1, a conventional injector apparatus 10 for injecting a liquid contrast media into a vascular system of an animal is disclosed in U.S. Pat. No. 5,383,858, which is incorporated herein by reference. This injector apparatus 10 has a front-loading construction. The apparatus of FIG. 1 utilizes a syringe 12 capable of being front-loaded into a mounting assembly 14 associated with a front wall 16 of a housing 18 of an injector 20 by a first releasable mechanism 22. The syringe 12 is capable of functioning in an injection operation without the use of a pressure jacket (although the syringe may be used in an injector with a pressure jacket).


With continued reference to FIG. 1, the mounting assembly 14 is provided with an essentially cylindrical interface 26 for receiving a rearward end of the syringe 12. The interface 26 includes an annular surface 28, which may be cylindrical or conically tapered. The annular surface 28 includes a distal ledge, which is engaged by tabs 30 on the rearward end of the syringe 12. The syringe 12 is inserted into the cylindrical interface 26 until the tabs 30 engage the distal ledge to secure the syringe 12 to the injector 20.


The syringe 12 comprises an elongated main tubular body or barrel 32 and a coaxial discharge injection section 34, interconnected by an intermediate conical portion 36. A plunger 38 is slidably positioned within the tubular body 32 and is connectable to a second releasable mechanism 40 on a piston 42 in the injector housing 18. The second releasable mechanism 40 is formed in part by the plunger 38 and in part by the piston 42.


The piston 42 and plunger 38 cooperate to eject fluid contained within the syringe 12 in a desired quantity and at a desired rate. The second releasable mechanism 40 is designed to facilitate axial movement of the plunger 38 in either direction when actuated. The second releasable mechanism 40 is also designed to engage or disengage the plunger 38 from the piston 42 no matter where the plunger 38 sits in tubular body 32.


In operation, the syringe 12 is mounted by inserting the syringe 12 into the interface 26 in the mounting assembly 14. The tabs 30 initially move past the annular surface 28 where they engage the distal ledge to securely hold the syringe 12 to the mounting assembly 14. The mounting assembly 14 further includes a forwardly projecting annular ring or collar 44, which functions to assure perpendicular engagement between the plunger 38 and piston 42. As explained above, the forwardly projecting annular ring or collar 44 also functions as a seal between a resilient annular sealing flange 46 on the syringe 12 and the mounting assembly 14.


The resilient annular sealing flange 46 surrounds the tubular body 32 of the syringe 12 and is disposed forward of the tabs 30 a preselected distance essentially equal to a width of the annular surface 28. Thus, when the syringe 12 is inserted into the interface 26 in the mounting assembly 14 until the sealing flange 46 engages the annular ring 44, the annular ring 44 and flange 46 create a seal between the syringe 12 and the mounting assembly 14.


With further reference to FIG. 1, the apparatus also includes a system for transmitting syringe information from the syringe 12 to an injector controller 51. The syringe 12 is provided with an encoding device 48 forward of the tabs 30 but rearward of the flange 46. When attaching the syringe 12 to the mounting assembly 14, if the syringe 12 is rotated after the tabs 30 engage the distal ledge, a sensor 50 is provided in the annular surface 28 to read the encoding device 48. The sensor 50 then forwards the associated signals to the injector controller 51, which interprets the signals and modifies the function of the injector 20 accordingly. Examples of the information which could be encoded on the encoding device 48 include dimensions of the syringe 12, volume of the syringe 12, content of the syringe 12 (in the case of a pre-filled syringe), manufacturing information such as lot numbers, dates and tool cavity number, recommended contrast media flow rates and pressures, and loading/injection sequences.


As an alternative to the encoding device 48 being a bar code, the encoding device 48 also could include machine-readable raised or recessed surfaces. In addition, the tubular body 32 of the syringe 12 also may be provided with an indicating mechanism 52 for readily detecting the presence or absence of a liquid contrast media in the syringe 12. In this instance, the indicating mechanism 52 includes a plurality of integrally molded, textured dots on the syringe 12, which provide a visual indication of whether the syringe 12 contains liquid or air.


Accordingly, while the above injector and syringe apparatus have proven effective, the engagement reliability of the mounting assembly 14 discussed hereinabove was found to be insufficient. Accordingly, a need has arisen for a more reliable syringe/injector engagement interface.


SUMMARY

According to one aspect of the device of the present disclosure, provided is an injector system for injecting fluid that includes a syringe and an injector. The syringe includes: a body comprising a rearward end and a forward end; a plunger movably disposed within the body; at least one syringe drive paw positioned toward the rearward end of the body; and a syringe engagement flange positioned toward the rearward end of the body and extending around a circumference of the body. The injector includes: a housing having a front plate defining a syringe-receiving opening therein and a drive member at least partially disposed within the housing and operable to engage the plunger disposed within the syringe. The syringe latch has a plurality of latch members extending toward a center of the syringe-receiving opening and configured to move from a closed position to an open position when a force is applied thereto and from the open position to the closed position when the force is removed therefrom. The syringe engagement flange pushes against the plurality of latch members of the syringe latch to open the syringe latch as axial rearward motion is applied to the syringe relative to the syringe latch and the plurality of latch members return to the closed position to retain the syringe within the opening of the housing when the syringe is fully seated within the housing.


The injector may further include a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing. The syringe release gear may be mounted to a rear side of the front plate by at least one syringe release cam pin. The syringe release gear may also include an opening formed therein that is aligned with the syringe-receiving opening of the front plate. The opening in the syringe release gear may include a plurality of teeth formed around a circumference thereof. In addition, the syringe drive paw may be configured to engage the plurality of teeth of the opening of the syringe release gear.


The syringe may be disengaged from the injector after completion of an injection procedure by rotating the syringe. This causes rotation of the syringe release gear via the engagement between the syringe drive paw and the plurality of teeth of the syringe release gear. The plurality of latch members of the syringe latch are thereby forced into the open position which allows a user to remove the syringe from the housing of the injector. The syringe desirably includes two syringe drive paws that are positioned toward the rearward end of the body located 180° degrees apart


The syringe latch may include two latch members, three latch members, or any other suitable number of latch members. Each of the plurality of latch members of the syringe latch may include a first portion and an arc-shaped second portion extending from the first portion. The arc-shaped second portion, when viewed in cross-section, may include a sloping face. The syringe latch may be manufactured from a polymeric material.


According to another aspect of the present disclosure, also provided is a method for engaging a syringe with an injector. The method includes: providing a syringe having a body with a rearward end and a forward end, a plunger movably disposed within the body, a syringe drive paw positioned toward the rearward end of the body, and a syringe engagement flange positioned toward the rearward end of the body and extending around a circumference of the body; providing an injector that includes a housing having a front plate defining a syringe-receiving opening therein, a drive member at least partially disposed within the housing and operable to engage the plunger disposed within the syringe; and a syringe latch mounted to a front side of the front plate and comprising a plurality of latch members extending toward a center of the syringe-receiving opening and configured to move from a closed position to an open position when a force is applied thereto and from the open position to the closed position when the force is removed therefrom; applying axial rearward motion to the syringe relative to the syringe latch such that the syringe engagement flange pushes against the plurality of latch members of the syringe latch to open the syringe latch; and returning the plurality of latch members of the syringe latch to the closed position to retain the syringe within the opening of the housing when the syringe is fully seated within the housing.


According to another aspect of the present disclosure, an injector system for injecting fluid may include a syringe having a body comprising a rearward end and a forward end, and a plunger movably disposed within the body, the plunger having at least one flexible leg extending toward the rearward end of the body. The injector system may further include an injector having a housing having a front plate defining a syringe-receiving opening therein, a drive member at least partially disposed within the housing and operable to engage the plunger disposed within the syringe and releasably connect the at least one flexible leg to at least a portion of the drive member, a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing, the syringe release gear mounted to a rear side of the front plate, and a plunger release tube surrounding at least a portion of the drive member, the plunger release tube having a first end rotationally engaged with the syringe release gear. Rotation of the syringe release gear may rotate and axially move the plunger release tube relative to the drive member to engage the at least one flexible leg and release the at least one flexible leg from the drive member.


According to a further aspect of the present disclosure, the syringe release gear may be mounted to a rear side of the front plate by at least one syringe release cam pin. The syringe release cam pin may extend through the front plate. The syringe release gear may include an opening formed therein that is aligned with the syringe-receiving opening of the front plate. The opening in the syringe release gear may include a plurality of teeth formed around a circumference thereof. At least one syringe drive paw may be positioned toward the rearward end of the body and a syringe engagement flange may be positioned toward the rearward end of the body and extending around a circumference of the body. The injector may further include a syringe latch mounted to a front side of the front plate, the syringe latch comprising a plurality of latch members extending toward a center of the syringe-receiving opening and configured to move from a closed position to an open position when a force is applied thereto and from the open position to the closed position when the force is removed therefrom, The syringe engagement flange may push against the plurality of latch members of the syringe latch to open the syringe latch as axial rearward motion is applied to the syringe relative to the syringe latch and the plurality of latch members return to the closed position to retain the syringe within the opening of the housing when the syringe is fully seated within the housing. The syringe drive paw may be configured to engage a plurality of teeth formed on the syringe release gear. The syringe may be disengaged from the injector after completion of an injection procedure by rotating the syringe, which causes rotation of the syringe release gear via the engagement between the syringe drive paw and a plurality of teeth of the syringe release gear, thereby forcing the plurality of latch members into the open position and allowing a user to remove the syringe from the housing of the injector. Each of the plurality of latch members of the syringe latch may include a first portion and an arc-shaped second portion extending from first portion. The arc-shaped portion may include a slot formed therein. The syringe may include two syringe drive paws positioned toward the rearward end of the body and located 180° degrees apart.


According to another aspect of the present disclosure, a front-loading medical injector system may include a syringe having a body comprising a rearward end and a frontward end, and a plunger movably disposed within the body, the plunger having at least one flexible leg extending toward the rearward end of the body. The injector system may further include an injector having a housing having a front plate defining a syringe-receiving opening therein, a drive member at least partially disposed within the housing and operable to engage the plunger disposed within the syringe and releasably connect the at least one flexible leg to at least a portion of the drive member, and a syringe release assembly operable to release the syringe. Rotation of the syringe release assembly may release the at least one flexible leg from the drive member. The syringe release assembly may include a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing, the syringe release gear mounted to a rear side of the front plate, and a plunger release tube surrounding at least a portion of the drive member, the plunger release tube having a first end rotationally engaged with the syringe release gear. Rotation of the syringe release gear may rotate and axially move the plunger release tube relative to the drive member to engage the at least one flexible leg and release the at least one flexible leg from the drive member. The injector may further include a syringe latch mounted to a front side of the front plate for securing the syringe to the injector. The syringe latch may have a plurality of latch members extending toward a center of the syringe-receiving opening and configured to move from a closed position to an open position when a force is applied thereto and from the open position to the closed position when the force is removed therefrom. At least one syringe drive paw may be positioned toward the rearward end of the body, and a syringe engagement flange may positioned toward the rearward end of the body and extending around a circumference of the body. The syringe engagement flange may push against the plurality of latch members of the syringe latch to open the syringe latch as axial rearward motion is applied to the syringe relative to the syringe latch and the plurality of latch members return to the closed position to retain the syringe within the opening of the housing when the syringe is fully seated within the housing. Each of the plurality of latch members of the syringe latch may include a first portion and an arc-shaped second portion extending from first portion.


These and other features and characteristics of the device of the present disclosure, as well as the methods of operation and functions of the related elements of structures and the combination of parts and economies of manufacture, will become more apparent upon consideration of the following description and the appended claims with reference to the accompanying drawings, all of which form a part of this specification, wherein like reference numerals designate corresponding parts in the various figures. It is to be expressly understood, however, that the drawings are for the purpose of illustration and description only and are not intended as a definition of the limits of the device of the present disclosure. As used in the specification and the claims, the singular form of “a”, “an”, and “the” include plural referents unless the context clearly dictates otherwise.





BRIEF DESCRIPTION OF THE DRAWINGS


FIG. 1 is a perspective view of a conventional injector system showing an injector housing and a syringe in a disassembled relationship;



FIG. 2 is a cross-sectional view of an injector system in accordance with an embodiment of the disclosure showing the syringe and the injector housing in a partially disassembled relationship;



FIG. 3 is a top plan view of the syringe latch in accordance with an embodiment of the disclosure for connecting the syringe to the injector housing;



FIGS. 4A-4E are cross-sectional views of a portion of the injector system of FIG. 2 illustrating the steps required for loading a syringe into the injector housing;



FIG. 5 is a cross-sectional view of the injector system of FIG. 2 showing the syringe and the injector housing in the assembled state;



FIG. 6 is a cross-sectional view of the injector system of FIG. 2 taken along line B-B;



FIG. 7 is a cross-sectional view of the injector system of FIG. 2 taken along line A-A;



FIGS. 8A-8D are cross-sectional views of a portion of the injector system of FIG. 5 illustrating the steps required for unloading a syringe from the injector housing;



FIG. 9 is a perspective view of an injector in accordance with an alternative embodiment of the disclosure;



FIG. 10 is a perspective view of the injector of FIG. 9 having the faceplate removed such that an alternative embodiment of the syringe latch is visible;



FIG. 11 is a perspective view of the injector of FIG. 10 with syringes attached thereto;



FIG. 12 is a perspective view of the injector of FIG. 9 with syringes attached thereto;



FIG. 13 is a side view of a syringe configured to be used with the injector of FIG. 9; and



FIG. 14 is are front views of the syringe latch of the injector of FIG. 9.





DETAILED DESCRIPTION

For purposes of the description hereinafter, the terms “upper”, “lower”, “right”, “left”, “vertical”, “horizontal”, “top”, “bottom”, “lateral”, “longitudinal”, and derivatives thereof, shall relate to the device of the present disclosure as it is oriented in the drawing figures. However, it is to be understood that the device of the present disclosure may assume various alternative variations, except where expressly specified to the contrary. It is also to be understood that the specific devices illustrated in the attached drawings, and described in the following specification, are simply exemplary embodiments of the device of the present disclosure. Hence, specific dimensions and other physical characteristics related to the embodiments disclosed herein are not to be considered as limiting.


With reference to FIG. 2, an injector system 100 for injecting a liquid contrast media into a vascular system of an animal is provided. The injector system 100 has a front-loading construction. The system of FIG. 2 utilizes a syringe 102 capable of being front-loaded into a mounting assembly 104 associated with a front plate 106 of a housing (not shown) of an injector 108 by a first releasable mechanism 22. The syringe 102 is capable of functioning in an injection operation without the use of a pressure jacket (although the syringe may be used in an injector with a pressure jacket).


The syringe 102 includes an elongated main tubular body or barrel 110 and a coaxial discharge injection section 112 interconnected by an intermediate conical portion 114. A plunger 116 is slidably positioned within the tubular body 110 and includes at least one plunger connect flex leg 118 that is connectable to a piston/plunger interface 120 on a piston 122 of the injector 108. The plunger 116 also includes a plunger sense interrupter 123 extending from a central portion thereof in the direction of the at least one flex leg 118. The plunger sense interrupter 123 is configured to interrupt a light path produced by an IR transmitter 140 and IR receiver 142 through a fiber optic cable 144 extending along the length of the piston 122, thereby providing a signal to an injector controller (not shown) that the syringe 102 is fully seated within the injector 108. An alternative embodiment of the plunger sense interrupter 123 determines the presence/absence of the syringe 102 without the use of a fiber optic cable.


The syringe 102 further includes a syringe engagement flange 124 positioned toward the rearward end of the body 110 and extending around a circumference of the body 110. When viewed in cross-section, the syringe engagement flange 124 includes a sloping section 126, a shoulder section 128 extending from the sloping section 126 that is essentially perpendicular to an exterior surface of the body 110 of the syringe 102, and an engagement section 130 extending from the shoulder section 128. The engagement section 130 is configured to engage a plurality of teeth 132 of an opening 134 of a syringe release gear 136 of the injector 108 as discussed in greater detail hereinafter in relation to FIG. 6.


Since the syringe 102 is being used in this embodiment without a pressure jacket, for strength and visibility of the contents of the syringe 102, the syringe 102 may be formed of a clear PET polyester material. In the alternative, the wall of the syringe 102 may be formed of polypropylene reinforced by providing a series of annular ribs on the tubular body 110 of the syringe 102 in a longitudinally spaced relationship. In addition, the syringe 102 desirably includes an encoding device for providing information regarding the syringe 102 to the injector 108 an indicating mechanism for readily detecting the presence or absence of a liquid contrast media in the syringe 102 similar to the encoding device and indicating mechanism of syringe 12 discussed hereinabove.


With continued reference to FIG. 1, the injector includes a housing (not shown) having the front plate 106 defining a syringe-receiving opening 138 therein. The piston 122 is positioned within the housing and is configured to extending into and out of the syringe-receiving opening 138 under the power of a drive mechanism 146. The piston 122 includes the piston/plunger interface 120 at an end thereof that is operable to interact with the at least one flex leg 118 of the plunger 116 to engage the plunger 116 disposed within the syringe 102.


With reference to FIG. 3 and with continuing reference to FIG. 2, the injector 108 also includes a syringe latch 148 mounted to a front side of the front plate 106 by any suitable fastening device 150 for maintaining the syringe in the seated position within the injector 108. The syringe latch 148 comprises a substantially oval shaped body member 152 and a plurality of latch members 154 extending toward a center C of the body member 152. In the embodiment of the syringe latch 148 illustrated in FIG. 3, two latch members 154 are included. The syringe latch 148 is desirably manufactured from a resilient, polymeric material such that the latch members 154 are configured to move from a closed position to an open position when a force is applied thereto and from the open position to the closed position when the force is removed therefrom.


Each of the plurality of latch members 154 of the syringe latch 148 includes a first portion 156 extending from the body member 152 and an arc-shaped second portion 158 extending from the first portion 156 and configured to engage the syringe engagement flange 124 of the syringe 102. The arc-shaped second portion 158, when viewed in cross-section, may include a sloping face 160 (see FIGS. 4A-4E) that engages with the sloping section 126 of the syringe engagement flange 124 to force the syringe latch 148 into the open position.


With continued reference to FIG. 2, the injector 108 also includes the syringe release gear 136 that forms an enclosure 162 for receiving the syringe 102 when the syringe 102 is fully seated within the injector housing. The syringe release gear 136 is mounted to a rear side of the front plate 106 by at least one syringe release cam pin 164. The syringe release cam pin 164 is configured to be connected to the syringe release gear 136 and extend through the front plate 106 of the injector 108 into a slot 166 in the arc-shaped second portion 158 of the latch members 154 of the syringe latch 148.


With reference to FIG. 7 and with continued reference to FIG. 2, the piston 122 is surrounded by a plunger release tube 168. The plunger release tube 168 has a first end that is rotationally engaged with the syringe release gear 136 such that rotation of the syringe release gear 136 causes rotation of the plunger release tube 168.


The process for engaging a syringe 102 with the injector 108 to form an injector system 100 is illustrated in FIGS. 4A-4E. This process allows for syringe engagement with an injector 108 that provides a syringe engagement adapted to releasably engage the syringe 102 with the injector 108 regardless of the rotational orientation of the syringe 102 with respect to the injector 108. The syringe engagement uses the flex legs 118 attached to the back side of the plunger 116 of the syringe 102 and a corresponding feature on the piston 122 of an injector 108 that provides axial engagement that does not require any specific rotational orientation of the syringe 102 to releasably engage with the injector 108. Additionally, a feature (i.e., the syringe engagement flange 124) is provided on the outside surface of the rear portion of the tubular body 110 to transfer rotational movement of the syringe into a release mechanism (i.e., the syringe release gear 136) implemented in the injector 108 releasing both the syringe 102 and the plunger 116 regardless of the axial position of the engaged syringe plunger 116.


The first step in the process for engaging the syringe 102 with the injector 108 is shown in FIG. 4A in which the syringe 102 is positioned axially with the syringe-receiving opening 134 of the front plate 106 of the injector 108 and is moved axially along the piston 122 into the enclosure 162 formed by the syringe release gear 136 in the direction of arrow A1. With reference to FIG. 4B, as the syringe 102 is inserted, the sloping section 126 of the syringe engagement flange 124 engages the sloping face 160 of the arc-shaped second section 158 of the latch members 154 of the syringe latch 148 and pushes the syringe latch 148. In addition, with reference to FIGS. 4C and 4D, as the syringe 102 is inserted, the sloped surface of the piston/plunger interface 120 flexes the at least one flex leg 118 of the plunger 116 open. With reference to FIG. 4E, continual movement of the syringe 102 in the direction of arrow A1 causes the syringe 102 to be fully seated within the enclosure 162 formed by the syringe release gear 136. When the body of the syringe 102 is fully seated within the enclosure 162 formed by the syringe release gear 136, the following items occur: first, the engagement section 130 of the syringe engagement flange 124 engages the teeth 132 of the syringe release gear 136. In addition, the syringe engagement flange 124 moves beyond the arc-shaped second portion 158 of the latch members 154 of the syringe latch 148, thereby closing the syringe latch 148 to retain the syringe 102. Desirably, when the syringe latch 148 returns to the closed position, it provides an audible “click” to indicate to the operator that the syringe 102 has been installed on the injector 108. Furthermore, the flex legs 118 on the plunger 116 flex closed engaging the piston/plunger interface 120. Finally, the plunger sense interrupter 123 of the plunger 116 interrupts the light path produced by an IR transmitter 140 and IR receiver 142 through a fiber optic cable 144 extending along the length of the piston 122, thereby providing a signal to an injector controller (not shown) that the syringe 102 is fully seated within the injector 108.


Removal of the syringe 102 from the injector 108 upon the completion of an injection procedure requires that the syringe 102 be rotated, as described below. This operation is illustrated in and described by reference to FIGS. 8A-8D.


With reference to FIG. 8A and FIG. 8B, the rotation of the syringe 102 causes rotation of the syringe release gear 136 via the engagement between the engagement section 130 of the syringe engagement flange 124 and the plurality of teeth 132 of the syringe release gear 136 as shown in FIG. 6. This rotation, in turn, causes rotation of the syringe release cam pins 164 along the slots 166 provided in the latch members 154 of the syringe latch 148 as shown in FIG. 8C. The latch members 154 of the syringe latch 148 are thereby forced into the open position.


As also shown in FIG. 8C, the rotation of the syringe release gear 136 also rotates the plunger release tube 168 about the piston 122 since the plunger release tube 168 is coupled to the syringe release gear 136 as described hereinabove. The rotation of the plunger release tube 168 about the piston 122 causes a cam action at a release cam surface 170 (see FIGS. 1 and 5) causing an axial extension of the plunger release tube 168 towards the syringe-receiving opening 134 of the front plate 106. The axial extension of the plunger release tube 168 forces the at least one flex leg 118 of the plunger 116 to flex open to release the piston/plunger interface 122.


At this point, a user can remove the syringe 102 from the housing of the injector 108. Once the syringe 102 is removed, the syringe release gear 136 returns to original position allowing the syringe latch 148 to return to the closed position and the plunger release tube 168 to drop down as shown in FIG. 8D.


While the syringe latch 148 discussed hereinabove includes two latch members, this is not to be construed as limiting the disclosure as any suitable number of latch members may be utilized. For instance, with reference to FIGS. 9-14, the injector may be embodied as a dual syringe injector system 200 that includes a pair of syringes 202a, 202b and an injector 204. As shown in FIGS. 10 and 11, the injector 204 utilizes a syringe latch 206a, 206b for each of the syringes 202a, 202b that includes three latch members 208 for engaging the syringe 202a, 202b within the injector 204. In addition, rather than having the latch members 208 connected to a body member as with the syringe latch 148 discussed hereinabove, each of the latch members 208 is independent and utilizes a spring return 210 (see FIG. 14).


More specifically, with reference to FIGS. 13 and 14, a syringe 202a, 202b for use with injector 204 includes a body 212 comprising a rearward end 214 and a forward end 216; a plunger (not shown) movably disposed within the body 212; and at least one syringe drive paw 218 positioned toward the rearward end 214 of the body 216. Desirably, the syringe 202a, 202b includes a pair of syringe drive paws 218 at the rearward end 214 of the body 216 located 180° apart. The syringe 202a, 202b also includes a syringe engagement flange 220 positioned toward the rearward end 214 of the body 212 and extending around a circumference of the body 212.


The injector 204 includes a pair of syringe latches 206a, 206b mounted to a front side of the front plate thereof. Each of the syringe latches 206a, 206b comprises a plurality of latch members 208 extending toward a center of the syringe-receiving opening 222 and configured to move from a closed position to an open position when a force is applied thereto and from the open position to the closed position when the force is removed therefrom. The syringe engagement flange 220 pushes against the plurality of latch members 208 of the syringe latch 206a, 206b to open the syringe latch 206a, 206b as axial rearward motion is applied to the syringe 202a, 202b relative to the syringe latch 206a, 206b and the plurality of latch members 208 return to the closed position to retain the syringe 202a, 202b within the opening 222 of the injector 204 when the syringe 202a, 202b is fully seated within the injector 204.


The syringe 202a, 202b may be disengaged from the injector 204 after completion of an injection procedure by rotating the syringe 202a, 202b. This causes rotation of a syringe release gear 224 via the engagement between the syringe drive paws 218 and a plurality of teeth of the syringe release gear 224. The rotation of the syringe release gear 224 activates the spring returns 210, which force the latch members 208 of the syringe latch 206a, 206b into the open position, thereby allowing a user to remove the syringe 202a, 202b from the injector 204.


While specific embodiments of the device of the present disclosure have been described in detail, it will be appreciated by those skilled in the art that various modifications and alternatives to those details could be developed in light of the overall teachings of the disclosure. Accordingly, the particular arrangements disclosed are meant to be illustrative only and not limiting as to the scope of the device of the present disclosure which is to be given the full breadth of the claims appended and any and all equivalents thereof.

Claims
  • 1. An injector system for injecting a fluid comprising: a syringe comprising: a body comprising a rearward end and a forward end;a plunger movably disposed within the body, the plunger having at least one flexible leg extending toward the rearward end of the body; andan injector comprising: a housing having a front plate defining a syringe-receiving opening therein;a drive member at least partially disposed within the housing and operable to engage the plunger disposed within the syringe and releasably connect the at least one flexible leg to at least a portion of the drive member;a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing, the syringe release gear mounted to a rear side of the front plate; anda plunger release tube surrounding at least a portion of the drive member, the plunger release tube having a first end rotationally engaged with the syringe release gear and a second end opposite the first end,wherein rotation of the syringe release gear rotates the plunger release tube and rotation of the plunger release tube causes a cam action at a release cam surface provided at the second end of the plunger release tube causing an axial extension of the plunger release tube relative to the drive member such that the plunger release tube engages the at least one flexible leg and releases the at least one flexible leg from the drive member.
  • 2. The injector system of claim 1, wherein the syringe release gear is mounted to the rear side of the front plate by at least one syringe release cam pin.
  • 3. The injector system of claim 2, wherein the at least one syringe release cam pin extends through the front plate.
  • 4. The injector system of claim 1, wherein the syringe release gear includes an opening formed therein that is aligned with the syringe-receiving opening of the front plate.
  • 5. The injector system of claim 4, wherein the opening in the syringe release gear includes a plurality of teeth formed around a circumference thereof.
  • 6. The injector system of claim 1, further comprising at least one syringe drive paw positioned toward the rearward end of the body; and a syringe engagement flange positioned toward the rearward end of the body and extending around a circumference of the body.
  • 7. The injector system of claim 6, further comprising a syringe latch mounted to a front side of the front plate, the syringe latch comprising a plurality of latch members extending toward a center of the syringe-receiving opening and configured to move from a closed position to an open position when a force is applied thereto and from the open position to the closed position when the force is removed therefrom, wherein the syringe engagement flange pushes against the plurality of latch members of the syringe latch to open the syringe latch as axial rearward motion is applied to the syringe relative to the syringe latch and the plurality of latch members return to the closed position to retain the syringe within the opening of the housing when the syringe is fully seated within the housing.
  • 8. The injector system of claim 7, wherein each of the plurality of latch members of the syringe latch includes a first portion and an arc-shaped second portion extending from the first portion.
  • 9. The injector system of claim 8, wherein the arc-shaped portion includes a slot formed therein.
  • 10. The injector system of claim 6, wherein the syringe drive paw is configured to engage a plurality of teeth formed on the syringe release gear.
  • 11. The injector system of claim 6, wherein the syringe is disengaged from the injector after completion of an injection procedure by rotating the syringe, which causes rotation of the syringe release gear via an engagement between the at least one syringe drive paw and a plurality of teeth of the syringe release gear, thereby forcing a plurality of latch members into an open position and allowing a user to remove the syringe from the housing of the injector.
  • 12. The injector system of claim 1, wherein the syringe includes two syringe drive paws positioned toward the rearward end of the body and located 180° degrees apart.
  • 13. A method for engaging a syringe with an injector, comprising: providing the syringe comprising: a body comprising a rearward end and a forward end;a plunger movably disposed within the body, the plunger having at least one flexible leg extending toward the rearward end of the body; andproviding the injector comprising: a housing having a front plate defining a syringe-receiving opening therein;a drive member at least partially disposed within the housing and operable to engage the plunger disposed within the syringe and releasably connect the at least one flexible leg to at least a portion of the drive member;a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing, the syringe release gear mounted to a rear side of the front plate; anda plunger release tube surrounding at least a portion of the drive member, the plunger release tube having a first end rotationally engaged with the syringe release gear and a second end opposite the first end;rotating the syringe release gear to rotate the plunger release tube;causing, by rotation of the plunger release tube, a cam action at a release cam surface provided at the second end of the plunger release tube causing an axial extension of the plunger release tube relative to the drive member such that the plunger release tube engages the at least one flexible leg and releases the at least one flexible leg from the drive member.
  • 14. The method claim 13, wherein the syringe release gear is mounted to the rear side of the front plate by at least one syringe release cam pin.
  • 15. The method of claim 14, wherein the at least one syringe release cam pin extends through the front plate.
  • 16. The method of claim 13, wherein the syringe release gear includes an opening formed therein that is aligned with the syringe-receiving opening of the front plate.
  • 17. The method of claim 16, wherein the opening in the syringe release gear includes a plurality of teeth formed around a circumference thereof.
CROSS-REFERENCE TO RELATED APPLICATIONS

This application claims priority to U.S. Provisional Application No. 61/955,527, filed Mar. 19, 2014 and U.S. Provisional Application No. 61/970,018, filed on Mar. 25, 2014, the disclosures of which are incorporated herein by reference in their entirety.

PCT Information
Filing Document Filing Date Country Kind
PCT/US2015/021171 3/18/2015 WO 00
Publishing Document Publishing Date Country Kind
WO2015/142995 9/24/2015 WO A
US Referenced Citations (388)
Number Name Date Kind
1265537 Ivan May 1918 A
1687323 Cook Oct 1928 A
1988480 Campkin Jan 1935 A
2392196 Smith Jan 1946 A
2419401 Hinds Apr 1947 A
2702547 Glass Feb 1955 A
2842126 Brown Jul 1958 A
3051173 Johnson et al. Aug 1962 A
D203730 Porat Feb 1966 S
3270483 Smoyer et al. Sep 1966 A
3348545 Sarnoff et al. Oct 1967 A
3468471 Linder Sep 1969 A
3604417 Stolzenberg et al. Sep 1971 A
3623474 Heilman Nov 1971 A
3645262 Harrigan Feb 1972 A
3701345 Heilman Oct 1972 A
3705582 Stumpf et al. Dec 1972 A
3720211 Kyrias Mar 1973 A
3738539 Beich Jun 1973 A
3752145 Runnells et al. Aug 1973 A
3796218 Burke et al. Mar 1974 A
3809082 Hurschman May 1974 A
3812843 Wootten et al. May 1974 A
3902491 Lajus Sep 1975 A
3964139 Kleinmann et al. Jun 1976 A
3987940 Tischlinger Oct 1976 A
3998224 Chiquiar-Arias Dec 1976 A
4006736 Kranys et al. Feb 1977 A
4030498 Tompkins Jun 1977 A
4080967 O'Leary Mar 1978 A
4144885 Stait Mar 1979 A
4148316 Xanthopoulos Apr 1979 A
4155490 Glenn May 1979 A
4159713 Prais Jul 1979 A
4180006 Ross Dec 1979 A
4180069 Walters Dec 1979 A
4226236 Genese Oct 1980 A
4252118 Richard et al. Feb 1981 A
4278086 Hodgins et al. Jul 1981 A
4303070 Ichikawa et al. Dec 1981 A
4345595 Whitney et al. Aug 1982 A
4351332 Whitney et al. Sep 1982 A
4356822 Winstead-Hall Nov 1982 A
4424720 Bucchianeri Jan 1984 A
4452251 Heilman Jun 1984 A
4453934 Gahwiler et al. Jun 1984 A
4464265 Joyner Aug 1984 A
4465472 Urbaniak Aug 1984 A
4465473 Ruegg Aug 1984 A
4475666 Bilbrey et al. Oct 1984 A
4476381 Rubin Oct 1984 A
4490256 Nussbaumer et al. Dec 1984 A
4493646 Lacour et al. Jan 1985 A
4500310 Christinger Feb 1985 A
4529401 Leslie et al. Jul 1985 A
4562844 Carpenter et al. Jan 1986 A
4568335 Updike et al. Feb 1986 A
4573978 Reilly Mar 1986 A
4585439 Michel Apr 1986 A
4604847 Moulding, Jr. et al. Aug 1986 A
4612010 Hamacher et al. Sep 1986 A
4617016 Blomberg Oct 1986 A
4628969 Jurgens, Jr. et al. Dec 1986 A
4636198 Stade Jan 1987 A
4648872 Kamen Mar 1987 A
4650475 Smith et al. Mar 1987 A
4652260 Fenton, Jr. et al. Mar 1987 A
4664128 Lee May 1987 A
4676776 Howson Jun 1987 A
4677980 Reilly et al. Jul 1987 A
4677981 Coursant Jul 1987 A
4681566 Fenton, Jr. et al. Jul 1987 A
4685903 Cable et al. Aug 1987 A
4695271 Goethel Sep 1987 A
4705509 Stade Nov 1987 A
4718463 Jurgens, Jr. et al. Jan 1988 A
4722734 Kolln Feb 1988 A
4741732 Crankshaw et al. May 1988 A
4741736 Brown May 1988 A
4749109 Kamen Jun 1988 A
4755172 Baldwin Jul 1988 A
4767406 Wadham et al. Aug 1988 A
4773900 Cochran Sep 1988 A
4791290 Noone et al. Dec 1988 A
4838857 Strowe et al. Jun 1989 A
4840616 Banks Jun 1989 A
4842581 Davis Jun 1989 A
RE32974 Porat et al. Jul 1989 E
4852768 Bartsch Aug 1989 A
4853521 Claeys et al. Aug 1989 A
4854324 Hirschman et al. Aug 1989 A
4863427 Cocchi Sep 1989 A
4869720 Chernack Sep 1989 A
4878896 Garrison et al. Nov 1989 A
4908022 Haber Mar 1990 A
4911695 Lindner Mar 1990 A
4923443 Greenwood et al. May 1990 A
4929238 Baum May 1990 A
4931043 Ray et al. Jun 1990 A
4932941 Min et al. Jun 1990 A
4936833 Sams Jun 1990 A
4943279 Samiotes et al. Jul 1990 A
4945363 Hoffman Jul 1990 A
4946009 Knutson Aug 1990 A
4950243 Estruch Aug 1990 A
4966601 Draenert Oct 1990 A
4969874 Michel et al. Nov 1990 A
4973309 Sultan Nov 1990 A
4978335 Arthur, III Dec 1990 A
4988337 Ito Jan 1991 A
4997423 Okuda et al. Mar 1991 A
5000735 Whelan Mar 1991 A
5007904 Densmore et al. Apr 1991 A
5019045 Lee May 1991 A
5024663 Yum Jun 1991 A
5033650 Colin et al. Jul 1991 A
5034004 Crankshaw Jul 1991 A
5047014 Mosebach et al. Sep 1991 A
5059179 Quatrochi et al. Oct 1991 A
5062832 Seghi Nov 1991 A
5078683 Sancoff et al. Jan 1992 A
5084017 Maffetone Jan 1992 A
5085638 Farbstein et al. Feb 1992 A
5085643 Larkin et al. Feb 1992 A
5090962 Landry, Jr. et al. Feb 1992 A
5093079 Bakaitis et al. Mar 1992 A
5094148 Haber et al. Mar 1992 A
5104374 Bishko et al. Apr 1992 A
5106372 Ranford Apr 1992 A
5106379 Leap Apr 1992 A
5122118 Haber et al. Jun 1992 A
5135507 Haber et al. Aug 1992 A
5147311 Pickhard Sep 1992 A
5153827 Coutre et al. Oct 1992 A
5176642 Clement Jan 1993 A
5181912 Hammett Jan 1993 A
5226897 Nevens et al. Jul 1993 A
5236416 McDaniel et al. Aug 1993 A
5242408 Jhuboo et al. Sep 1993 A
5246423 Farkas Sep 1993 A
5254086 Palmer et al. Oct 1993 A
5254101 Trombley, III Oct 1993 A
5256154 Liebert et al. Oct 1993 A
5256157 Samiotes et al. Oct 1993 A
5269762 Armbruster et al. Dec 1993 A
5275582 Wimmer Jan 1994 A
5279569 Neer et al. Jan 1994 A
5282792 Imbert Feb 1994 A
5282858 Bisch et al. Feb 1994 A
5300031 Neer et al. Apr 1994 A
5308330 Grimard May 1994 A
5314415 Liebert et al. May 1994 A
5317506 Coutre et al. May 1994 A
5324273 Discko, Jr. Jun 1994 A
5336189 Sealfon Aug 1994 A
5338309 Imbert Aug 1994 A
5342298 Michaels et al. Aug 1994 A
5353691 Haber et al. Oct 1994 A
5354287 Wacks Oct 1994 A
5356375 Higley Oct 1994 A
5356393 Haber et al. Oct 1994 A
5373684 Vacca Dec 1994 A
5380285 Jenson Jan 1995 A
5383858 Reilly et al. Jan 1995 A
5389075 Vladimirsky Feb 1995 A
5397313 Gross Mar 1995 A
5411488 Pagay et al. May 1995 A
5413563 Basile et al. May 1995 A
5425716 Kawasaki et al. Jun 1995 A
5429602 Hauser Jul 1995 A
5429611 Rait Jul 1995 A
5431627 Pastrone et al. Jul 1995 A
5433712 Stiles et al. Jul 1995 A
5439452 McCarty Aug 1995 A
5445622 Brown Aug 1995 A
5451211 Neer et al. Sep 1995 A
5456670 Neer et al. Oct 1995 A
D364461 Liebert et al. Nov 1995 S
5478314 Malenchek Dec 1995 A
5484413 Gevorgian Jan 1996 A
5512054 Morningstar Apr 1996 A
5520653 Reilly et al. May 1996 A
5531698 Olsen Jul 1996 A
5531710 Dang et al. Jul 1996 A
5533981 Mandro et al. Jul 1996 A
5535746 Hoover et al. Jul 1996 A
5540660 Jenson Jul 1996 A
5545140 Conero et al. Aug 1996 A
5573515 Wilson et al. Nov 1996 A
5593386 Helldin Jan 1997 A
5624408 Helldin Apr 1997 A
5658261 Neer et al. Aug 1997 A
5662612 Niehoff Sep 1997 A
5681285 Ford et al. Oct 1997 A
5681286 Niehoff Oct 1997 A
5683367 Jordan et al. Nov 1997 A
5688252 Matsuda et al. Nov 1997 A
5695477 Sfikas Dec 1997 A
5722951 Marano Mar 1998 A
5735825 Stevens et al. Apr 1998 A
5738655 Vallelunga et al. Apr 1998 A
5738659 Neer et al. Apr 1998 A
5741227 Sealfon Apr 1998 A
5741232 Reilly et al. Apr 1998 A
5779675 Reilly et al. Jul 1998 A
5782803 Jentzen Jul 1998 A
5785682 Grabenkort Jul 1998 A
5795333 Reilly et al. Aug 1998 A
5795337 Grimard Aug 1998 A
5807334 Hodosh et al. Sep 1998 A
5808203 Nolan, Jr. et al. Sep 1998 A
5827219 Uber, III et al. Oct 1998 A
5827262 Neftel et al. Oct 1998 A
5840026 Uber, III et al. Nov 1998 A
RE35979 Reilly et al. Dec 1998 E
D403762 Gabbard et al. Jan 1999 S
5865805 Ziemba Feb 1999 A
5873861 Hitchins et al. Feb 1999 A
D407362 Schardt Mar 1999 S
5879336 Brinon Mar 1999 A
5882343 Wilson et al. Mar 1999 A
5899885 Reilly et al. May 1999 A
5902276 Namey, Jr. May 1999 A
5913844 Ziemba et al. Jun 1999 A
5919167 Mulhauser et al. Jul 1999 A
5938637 Austin et al. Aug 1999 A
5938639 Reilly et al. Aug 1999 A
5944694 Hitchins et al. Aug 1999 A
5947929 Trull Sep 1999 A
5947935 Rhinehart et al. Sep 1999 A
5954697 Srisathapat et al. Sep 1999 A
5954700 Kovelman Sep 1999 A
5997502 Reilly et al. Dec 1999 A
5997511 Curie et al. Dec 1999 A
6004300 Butcher et al. Dec 1999 A
6017330 Hitchins et al. Jan 2000 A
6042565 Hirschman et al. Mar 2000 A
6048334 Hirschman et al. Apr 2000 A
6059756 Yeh May 2000 A
6080136 Trull et al. Jun 2000 A
6083197 Umbaugh Jul 2000 A
6083200 Grimm et al. Jul 2000 A
6090064 Reilly et al. Jul 2000 A
6099502 Duchon et al. Aug 2000 A
6129712 Sudo et al. Oct 2000 A
6162200 Sawa et al. Dec 2000 A
6196999 Goethel et al. Mar 2001 B1
6221045 Duchon et al. Apr 2001 B1
6224577 Dedola et al. May 2001 B1
6267749 Miklos et al. Jul 2001 B1
6312410 Yamamoto Nov 2001 B1
6315758 Neer et al. Nov 2001 B1
6322535 Hitchins et al. Nov 2001 B1
RE37487 Reilly et al. Dec 2001 E
6332877 Michels Dec 2001 B1
6336913 Spohn et al. Jan 2002 B1
6339718 Zatezalo et al. Jan 2002 B1
6345262 Madden Feb 2002 B1
6368307 Ziemba et al. Apr 2002 B1
6432089 Kakimi et al. Aug 2002 B1
6447487 Cane' Sep 2002 B1
6511459 Fago Jan 2003 B1
6517516 Caizza Feb 2003 B1
6533758 Staats et al. Mar 2003 B1
6569127 Fago et al. May 2003 B1
6582399 Smith et al. Jun 2003 B1
6585700 Trocki et al. Jul 2003 B1
6652489 Trocki et al. Nov 2003 B2
6659979 Neer et al. Dec 2003 B2
6669663 Thompson Dec 2003 B1
6676635 Nemoto Jan 2004 B2
6733477 Cowan et al. May 2004 B2
6733478 Reilly et al. May 2004 B2
6752789 Duchon et al. Jun 2004 B2
6764466 Staats et al. Jul 2004 B1
6808513 Reilly et al. Oct 2004 B2
6817990 Yap et al. Nov 2004 B2
6958053 Reilly Oct 2005 B1
7018363 Cowan et al. Mar 2006 B2
7025757 Reilly et al. Apr 2006 B2
7029459 Reilly Apr 2006 B2
7240882 Degentesh et al. Jul 2007 B2
7264612 Nemoto Sep 2007 B2
D555802 Coulling et al. Nov 2007 S
7300417 Goethel et al. Nov 2007 B1
7337538 Moutafis et al. Mar 2008 B2
7344520 Nemoto Mar 2008 B2
7393341 Nemoto Jul 2008 B2
7399293 Oyibo et al. Jul 2008 B2
7419478 Reilly et al. Sep 2008 B1
7455659 Nemoto et al. Nov 2008 B2
7462166 Kowan et al. Dec 2008 B2
7465290 Reilly Dec 2008 B2
7497843 Castillo et al. Mar 2009 B1
7501092 Chen Mar 2009 B2
7503906 Nemoto Mar 2009 B2
7540856 Trocki et al. Jun 2009 B2
7553294 Lazzaro et al. Jun 2009 B2
7566326 Duchon et al. Jul 2009 B2
7666169 Cowan et al. Feb 2010 B2
7682345 Savage Mar 2010 B2
7695457 Nemoto Apr 2010 B2
7803134 Sharifi et al. Sep 2010 B2
7854726 Fago et al. Dec 2010 B2
7875005 Nemoto Jan 2011 B2
D632389 Maeda et al. Feb 2011 S
D637492 Baird et al. May 2011 S
7972306 Shearn Jul 2011 B2
7998133 Fago et al. Aug 2011 B2
8012124 Fago et al. Sep 2011 B1
8012125 Fago et al. Sep 2011 B1
8038656 Lloyd et al. Oct 2011 B2
8070732 Rochette Dec 2011 B2
8105293 Pickhard Jan 2012 B2
8133203 Hack Mar 2012 B2
8172814 Cane May 2012 B2
8177757 Nemoto et al. May 2012 B2
D665498 Tamura et al. Aug 2012 S
8262644 Fago et al. Sep 2012 B2
8308689 Lewis Nov 2012 B2
8353879 Goethel et al. Jan 2013 B2
8454560 Strobl Jun 2013 B2
D686322 Maeda et al. Jul 2013 S
8475415 Schiller et al. Jul 2013 B2
8480631 Wotton et al. Jul 2013 B2
8574200 Hack Nov 2013 B2
8585658 Forstreuter Nov 2013 B2
8597246 Fago et al. Dec 2013 B1
8613730 Hieb et al. Dec 2013 B2
8628495 Horton et al. Jan 2014 B2
8721596 Trocki et al. May 2014 B2
8740854 Schiller et al. Jun 2014 B2
8740856 Quinn et al. Jun 2014 B2
8845596 Berman et al. Sep 2014 B2
8851866 Moutafis et al. Oct 2014 B2
8857674 Nighy et al. Oct 2014 B2
8864712 Fago et al. Oct 2014 B1
8926569 Bisegna et al. Jan 2015 B2
8932255 Fago et al. Jan 2015 B1
9173995 Tucker et al. Nov 2015 B1
9174003 Cowan et al. Nov 2015 B2
9199033 Cowan et al. Dec 2015 B1
9474857 Riley et al. Oct 2016 B2
9694131 Cowan et al. Jul 2017 B2
9844622 Savage et al. Dec 2017 B2
20020165491 Reilly Nov 2002 A1
20030004468 Righi et al. Jan 2003 A1
20030009133 Ramey Jan 2003 A1
20030120219 Nielsen et al. Jun 2003 A1
20030153877 Huang et al. Aug 2003 A1
20030163089 Bynum Aug 2003 A1
20030216683 Shekalim Nov 2003 A1
20030236800 Goeltzenleuchter et al. Dec 2003 A1
20040006314 Campbell et al. Jan 2004 A1
20040039368 Reilly et al. Feb 2004 A1
20040074453 Roelle et al. Apr 2004 A1
20040116861 Trocki Jun 2004 A1
20040133153 Trocki et al. Jul 2004 A1
20040133183 Trocki et al. Jul 2004 A1
20040186437 Frenette et al. Sep 2004 A1
20040243022 Carney et al. Dec 2004 A1
20040243067 Sibbitt Dec 2004 A1
20050240149 Lu Oct 2005 A1
20060129104 Cowan et al. Jun 2006 A1
20060173411 Barere Aug 2006 A1
20070123830 Johannes, Sr. et al. May 2007 A1
20070191785 Barere et al. Aug 2007 A1
20090247957 Heutschi Oct 2009 A1
20100016796 Derichs Jan 2010 A1
20100280369 Bruce Sep 2010 A1
20100280370 Namey, Jr. Nov 2010 A1
20100318030 Jenkins Dec 2010 A1
20110178500 Shang et al. Jul 2011 A1
20110224611 Lum et al. Sep 2011 A1
20120039809 Levinson et al. Feb 2012 A1
20120172817 Bruggemann Jul 2012 A1
20120184920 Okihara et al. Jul 2012 A1
20120286187 Spolski Nov 2012 A1
20130150806 Fangrow, Jr. Jun 2013 A1
20130211325 Wang et al. Aug 2013 A1
20130317427 Brereton et al. Nov 2013 A1
20130317480 Reber et al. Nov 2013 A1
20130338605 Chen Dec 2013 A1
20140031763 Soma et al. Jan 2014 A1
20140200483 Fojtik Jul 2014 A1
20140243746 Trocki et al. Aug 2014 A1
20140330216 Weaver et al. Nov 2014 A1
20150025375 Pollard Jan 2015 A1
Foreign Referenced Citations (75)
Number Date Country
317487 Jan 2008 AU
2919978 Nov 1980 DE
3227417 Feb 1983 DE
4017920 Dec 1991 DE
19601214 Aug 1996 DE
19633530 Feb 1998 DE
0111724 Jun 1984 EP
0160303 Nov 1985 EP
0164904 Dec 1985 EP
0308380 Mar 1989 EP
0319275 Jun 1989 EP
0320168 Jun 1989 EP
0323321 Jul 1989 EP
0346950 Dec 1989 EP
0364010 Apr 1990 EP
0384657 Aug 1990 EP
0482677 Apr 1992 EP
0523343 Jan 1993 EP
0523434 Jan 1993 EP
0567944 Nov 1993 EP
0567945 Nov 1993 EP
0584531 Mar 1994 EP
0736306 Oct 1996 EP
0749757 Dec 1996 EP
0900573 Mar 1999 EP
0919251 Jun 1999 EP
0951306 Oct 1999 EP
0951306 Oct 1999 EP
1002551 May 2000 EP
1166807 Jan 2002 EP
1166807 Nov 2005 EP
847914 Sep 1960 GB
1380873 Jan 1975 GB
2108852 May 1983 GB
S61500415 Mar 1986 JP
S6327770 Feb 1988 JP
S6368177 Mar 1988 JP
2001029466 Feb 2001 JP
4462798 May 2010 JP
D1398129 Oct 2010 JP
D1398130 Oct 2010 JP
D1400385 Nov 2010 JP
D1400386 Nov 2010 JP
D1400551 Nov 2010 JP
D1400552 Nov 2010 JP
8002376 Nov 1980 WO
8500292 Jan 1985 WO
8502256 May 1985 WO
8906145 Jul 1989 WO
8909071 Oct 1989 WO
8911310 Nov 1989 WO
9001962 Mar 1990 WO
9104759 Apr 1991 WO
9221391 Dec 1992 WO
9413336 Jun 1994 WO
9425089 Nov 1994 WO
9632975 Oct 1996 WO
9707841 Mar 1997 WO
9736635 Oct 1997 WO
9820920 May 1998 WO
9965548 Dec 1999 WO
0137903 May 2001 WO
0137905 May 2001 WO
0204049 Jan 2002 WO
03101527 Dec 2003 WO
2004035289 Apr 2004 WO
2005053771 Jun 2005 WO
2007130061 Nov 2007 WO
2010139793 Dec 2010 WO
2011129175 Oct 2011 WO
2012124028 Sep 2012 WO
2012155035 Nov 2012 WO
2015006430 Jan 2015 WO
2016069711 May 2016 WO
2016069714 May 2016 WO
Non-Patent Literature Citations (33)
Entry
“International Preliminary Report on Patentability from Corresponding PCT Application No. PCT/US2015/021171”, dated Sep. 20, 2016.
“International Search Report and Written Opinion from corresponding PCT Application No. PCT/US2015/021171”, dated Jun. 23, 2015.
“Supplementary European Search Report in EP App. EP15765821”, dated Oct. 24, 2017.
Brochure for “Angiomat 6000” of Liebel-Farsheim, 2111 E. Galbraith Road, Cincinnati, OH 45215, © 1987.
Brochure for “Angiomat CT” of Liebel-Farsheim, 2111 E. Galbraith Road, Cincinnati, OH 45215, © 1988.
Brochure for “Cordis Lymphography Injector,” Cordis Corporation, Miami, FL 33137 (1972).
Brochure for “PercuPump 1A” of E-Z-Em, Inc, 717 Main Street, Westbury, NY 11590, © 1990.
Brochure for the “The First and Only True Injection System, ” Medrad Mark V System, Control No. 85106-00-BA-02, Nov. 1988.
The International Search Report from corresponding PCT Application PCT/US2013/061384 dated Feb. 20, 2014.
“Extended European Search Report and Opinion from EP15823049”, dated Feb. 1, 2017.
Feb. 23, 2015 ISR and WO from PCT/US2014/067435.
Injektron 82 MRT User Instructions, Version MR2, CEO535, Med-Tron GmbH(Mar. 10, 1999).
International Preliminary Report of Patentability dated Jan. 12, 2016 from PCT/US2014/045923.
International Search Report & Written Opinion for International Application No. PCT/US2004/039225, ISA/US, dated May 12, 2006.
“International Search Report and Written Opinion from PCT Application No. PCT/US2016/059245”, dated Mar. 10, 2017.
“International Search Report and Written Opinion from PCT Application No. PCT/US2016/059246”, dated Dec. 1, 2016.
International Search Report for Counterpart PCT Application No. PCT/US00/32271 dated Jul. 3, 2001.
International Search Report for International Application No. PCT/AU01/00830, dated Nov. 1, 2001.
International Search Report for International Application No. PCT/US03/17305, dated Oct. 21, 2003.
IPRP dated Jan. 12, 2016 from PCT/US2014/045923.
ISR dated Oct. 30, 2014 from PCT/US2014/045923.
ISR dated May 12, 2006 by PCT/US2004/039225.
ISR from PCT/US97/20122, dated Jun. 30, 1998.
Liebel-Flarsheim company—Angiomat 6000 Digital Injection System Operator's Manual, 600950 Rev 1 (1990); p. 3-6 to 3-8, 4-52 to 4-56.
Medrad Envision CT Injector Operation Manual, EOM 700E, 92401-T-123 Rev E, Copyright 1995.
Medrad Envision CT Injector Operation Manual, EOM 700E, 92401-T-123 Rev E, pp. 2-10 to 2-11 and pp. 2-30 to 2-35(Copyright 1995).
Medrad, Mark V/Mark V Plus Injector Operation Manual,KMP 805P Rev. B (1990); pp. 1-18 to 1-28, 3-7 to 3-13, 14-1 to 14-4.
Supplementary ESR from EP 01949108 dated Apr. 13, 2007.
Supplementary ESR from EP 01949108 dated Apr. 25, 2007.
Supplementary European Search Report dated Apr. 14, 2016 from EP13842045.
Supplementary Partial European Search Report for EP 01949108 dated Apr. 13, 2007.
The European Search Report dated Apr. 27, 2015 from corresponding EP Application No. EP14174725.
The International Preliminary Report on Patentability dated Apr. 9, 2015 from corresponding PCT Application No. PCT/US2013/061384.
Related Publications (1)
Number Date Country
20170080148 A1 Mar 2017 US
Provisional Applications (2)
Number Date Country
61970018 Mar 2014 US
61955527 Mar 2014 US