1. Technical Field
The present disclosure generally relates to electrosurgery. More particularly, the present disclosure relates to systems and methods for calibrating power measurements within an electrosurgical generator.
2. Background of Related Art
Electrosurgery involves the application of high-frequency electric current to cut or modify biological tissue during a surgical procedure. Electrosurgery is performed using an electrosurgical generator, an active electrode, and a return electrode. The electrosurgical generator (also referred to as a power supply or waveform generator) generates an alternating current (AC), which is applied to a patient's tissue through the active electrode and is returned to the electrosurgical generator through the return electrode. The alternating current typically has a frequency above 100 kilohertz to avoid muscle and/or nerve stimulation.
During electrosurgery, the alternating current generated by the electrosurgical generator is conducted through tissue disposed between the active and return electrodes. The tissue's impedance converts the electrical energy (also referred to as electrosurgical energy) associated with the alternating current into heat, which causes the tissue temperature to rise. The electrosurgical generator controls the heating of the tissue, by controlling the electric power (i.e., electrical energy per time) provided to the tissue. Although many other variables affect the total heating of the tissue, increased current density usually leads to increased heating. The electrosurgical energy is typically used for cutting, dissecting, ablating, coagulating, and/or sealing tissue.
The two basic types of electrosurgery employed are monopolar and bipolar electrosurgery. Both of these types of electrosurgery use an active electrode and a return electrode. In bipolar electrosurgery, the surgical instrument includes an active electrode and a return electrode on the same instrument or in very close proximity to one another, usually causing current to flow through a small amount of tissue. In monopolar electrosurgery, the return electrode is located elsewhere on the patient's body and is typically not a part of the electrosurgical instrument itself. In monopolar electrosurgery, the return electrode is part of a device usually referred to as a return pad.
An electrosurgical generator includes a controller that controls the power applied to a load, i.e., the tissue, over some period of time. The power applied to the load is controlled based upon the power determined at the output of the electrosurgical generator and a power level set by the user or a power level needed to achieve a desired tissue effect. The power at the output of the electrosurgical generator is determined by measuring the voltage and current at the output of the electrosurgical generator and calculating the average power based upon the measured voltage and current.
The voltage and current measured by the sensors at the output of the electrosurgical generator, however, may not equal the actual voltage and current applied to the load, i.e., the tissue, because of errors in the voltage and current measurements. These measurement errors may be caused by parasitics in the cable connecting the electrosurgical generator to the electrosurgical instrument, parasitics in the analog processing circuitry, and/or delays of the analog to digital conversion process. As a result, the power calculations may be inaccurate and may lead to improper control of the electrosurgical energy applied to the tissue.
The system and method of the present disclosure accurately determines the power actually applied to tissue by calibrating the power measurements within an electrosurgical generator using equalizers at a desired frequency or over a narrow bandwidth of frequencies. The equalizers have low computational complexity and may be implemented using commonly available microprocessors, field programmable gate arrays (FPGAs), or digital signal processors (DSPs).
In one aspect, the present disclosure features an electrosurgical generator system. This system includes an electrosurgical generator and an electrosurgical instrument coupled to the electrosurgical generator through an electrosurgical cable. The electrosurgical instrument is configured to apply electrosurgical energy to body tissue. The electrosurgical generator includes an radio frequency (RF) electrical energy source, a voltage detector coupled to the RF electrical energy source, a current detector coupled to the RF electrical energy source, an equalizer unit configured to equalize the voltage detected by the voltage detector and the current detected by the current detector, and a power calculation unit that calculates power based upon the equalized voltage and current.
In some embodiments, the electrosurgical generator includes a digital signal processor (DSP), which includes the equalizer unit and the power calculation unit. The equalizer unit may include a Least Mean Squares (LMS) adaptive filter, a gain and a fractional delay line, at least one gain and an all-pass delay filter, or a bandpass parametric equalizer. The bandpass parametric equalizer may be a shelving boost filter, a shelving cut filter, or a peak filter. The equalizer unit may also include a polyphase filter and decimator configured to perform equalization, filtering, and decimation as a combined function.
In some embodiments, the electrosurgical generator system further includes analog-to-digital converters electrically coupled to the current and voltage detectors. The power calculation unit calculates actual power applied to the electrosurgical instrument.
The present disclosure, in another aspect, features a method of controlling an electrosurgical generator system. The method includes generating RF electrical energy, sensing the voltage and current of the RF electrical energy, equalizing the voltage and current of the RF electrical energy, calculating power based upon the equalized voltage and current, and modifying the power of the RF electrical energy based upon the calculated power to achieve desired tissue effects.
In some embodiments, equalizing the voltage and current of the RF electrical energy includes filtering the sensed voltage and the sensed current with an LMS adaptive filter. In other embodiments, equalizing the sensed voltage and the sensed current of the RF electrical energy includes applying a gain to the sensed voltage and the sensed current and delaying the result of applying a gain to the sensed voltage and the sensed current to correct unequal group delay. The delay may be a fractional delay line filter. In yet other embodiments, equalizing the sensed voltage and the sensed current of the RF electrical energy includes applying a gain to the sensed voltage and the sensed current and filtering the result with an all-pass delay filter. In yet other embodiments, equalizing the sensed voltage and the sensed current of the RF electrical energy includes equalizing the sensed voltage and the sensed current of the RF electrical energy using a bandpass parametric equalizer, such as a shelving boost filter, a shelving cut filter, or a peak filter.
In some embodiments, the method includes converting the sensed voltage and current to digital form. Also, calculating power based upon the equalized voltage and current includes calculating the actual average power applied to a load. In addition, modifying the power of the RF electrical energy includes comparing the calculated power to a preset power value or desired power value based on the calculated tissue impedance, and modifying the power of the electrosurgical energy based upon the result of comparing the calculated power to the preset power value or desired power value.
The present disclosure, in yet another aspect, features a method of calibrating power measurements in an electrosurgical generator. The method includes selecting a resistive element; applying the resistive element across the output terminals of the electrosurgical generator; generating a test signal at a desired frequency; applying the test signal to the resistive element; measuring first magnitude values and first phase angle values of voltage and current components of the test signal at the output terminals; estimating second magnitude values and second phase angle values for the voltage and current components of the test signal using a first equalizer for the voltage component and a second equalizer for the current component; determining gain correction factors for the first and second equalizers based on the measured and estimated magnitudes of the voltage and current components of the test signal; and determining the minimum phase angle of the first and second equalizers based on the measured and estimated phase angles of the voltage and current components of the test signal.
Various embodiments of the present disclosure are described with reference to the accompanying drawings wherein:
The electrosurgical system 100 includes a monopolar electrosurgical instrument 114 having one or more electrodes 108 for treating tissue of a patient (e.g., an electrosurgical cutting probe or ablation electrodes). Electrosurgical energy, e.g., radio frequency (RF) current, is supplied to the instrument 114 by the electrosurgical generator 102 via a supply line 116, which is connected to an active terminal 104 of the electrosurgical generator 102, allowing the instrument 114 to coagulate, seal, ablate and/or otherwise treat tissue. The electrosurgical current returns from the tissue via a return line 118 of the return pad 110 to a return terminal 106 of the electrosurgical generator 102. The active terminal 104 and the return terminal 106 may include connectors (not explicitly shown) configured to interface with plugs (also not explicitly shown) disposed at the end of the supply line 116 of the instrument 114 and at the end of the return line 118 of the return pad 110.
The electrosurgical system 100 includes return electrodes 120 and 122 within return pad 110 that are arranged to minimize the risk of tissue damage by maximizing the overall contact area with the patient's tissue. In addition, the electrosurgical generator 102 and the return pad 110 may be configured to monitor tissue-to-patient contact to insure that sufficient contact exists between the return pad 110 and the patient to minimize the risk of tissue damage.
The electrosurgical system 100 also includes a bipolar electrosurgical forceps instrument 112 having two or more electrodes (e.g., electrodes 124, 126) for treating tissue of a patient. The instrument 112 includes opposing jaw members 134, 136. The first jaw member 134 includes an active electrode 124 and the second jaw member 136 includes a return electrode 126. The active electrode 124 and the return electrode 126 are connectable to the electrosurgical generator 102 through cable 128, which includes a supply line 130 and a return line 132. The supply line 130 is connectable to the active terminal 104 and the return line 132 is connectable to the return terminal 106. The instrument 112 connects to the active terminal 104 and the return terminal 106 of the electrosurgical generator 102 through a plug (not explicitly shown) disposed at the end of the cable 128.
The electrosurgical generator 102 may be any suitable type of generator (e.g., electrosurgical or microwave) and may include a plurality of connectors to accommodate various types of electrosurgical instruments (e.g., instrument 114 and electrosurgical forceps 112). The electrosurgical generator 102 may also be configured to operate in a variety of modes, such as ablation, monopolar cutting, bipolar coagulation, and other modes. The electrosurgical generator 102 may include a switching mechanism (e.g., relays) to switch the supply of RF energy between the connectors. For example, when the instrument 114 is connected to the electrosurgical generator 102, the switching mechanism switches the supply of RF energy to only the monopolar plug. The active terminal 104 and the return terminal 106 may be coupled to a plurality of connectors (e.g., inputs and outputs) of the electrosurgical generator 102 to power a variety of instruments.
The electrosurgical generator 102 includes suitable input controls (e.g., buttons, activators, switches, or touch screens) for controlling the electrosurgical generator 102. In addition, the electrosurgical generator 102 may include one or more display screens for providing the user with a variety of output information (e.g., intensity settings and treatment complete indicators). The controls allow the user to adjust parameters of the RF electrical energy (e.g., the power or the waveform) so that they are suitable for a particular task (e.g., coagulating, tissue sealing, or cutting). The instruments 112 and 114 may also include a plurality of input controls that may be redundant with certain input controls of the electrosurgical generator 102. Placing the input controls at the instruments 112 and 114 allow for easier and faster modification of RF energy parameters during the surgical procedure without requiring interaction with the electrosurgical generator 102.
Controller 200 may also include various circuitry (e.g., amplifiers or buffers) that serves as an interface between the microprocessor 206 and other circuitry within the electrosurgical generator 102. Controller 200 receives various feedback signals that are analyzed by the microprocessor 206 to provide control signals based on the feedback signals. The control signals from controller 200 control the HVPS 202 and the RF output stage 204 to provide electrosurgical energy to tissue, represented by a load 210 (
The HVPS 202 includes an energy conversion circuit 208, which converts AC from an AC source or direct current (DC) from a DC source at a first energy level into DC at a second different energy level. The energy conversion circuit 208 supplies the DC power at the second different energy level to the RF output stage 204 based on control signals from the controller 200. The RF output stage 204 inverts the DC power output from the energy conversion circuit 208 to produce a high-frequency alternating current (e.g., RF AC), which is applied to the load 210. For example, the RF output stage 204 may generate a high-frequency alternating current using push-pull transistors coupled to a primary side of a step-up transformer (not shown).
The electrosurgical generator 102 and controller 200 include circuitry that determines and controls the power actually applied to the load 210 (
Pavg=Vrms·Irm·cos φVI,
where Pavg is the average power in watts, Vrms is the root-mean-square value of the sinusoidal load voltage Vload, Irms is the root-mean-square value of the sinusoidal load current Iload, and φVI is the phase angle between the load voltage Vload and the load current Iload.
Alternatively, the average power may be calculated according to the equation:
where T is the averaging time constant, v(t) is the load voltage as a function of time, and i(t) is the load current as a function of time. The controller 200 uses the calculated average power at the load as feedback to control the energy conversion circuit 208 so that the average power at the load is equal to a power level set by the user to achieve a desired tissue effect.
As shown in
In some electrosurgical generators, the digital voltage and current signals are used to calculate the average power at the load. However, processing delays associated with the measurement circuitry (i.e., the sensors 211, 212 and ADCs 215) and electrical parasitic components in the cable 205 and in the measurement circuitry may introduce errors into the voltage and current measurements. Because of errors in the measurements, the magnitude of the measured voltage may not be equal to the magnitude of the voltage actually applied to the load 210, and/or the magnitude of the measured current may not be equal to the magnitude of the current actually applied to the load 210, and/or the phase difference between the measured voltage and current may not be equal to the phase difference between the voltage and current actually applied to the load 210. As a result, the average power calculated based on the magnitudes of the voltage and current and their phase difference may not be equal to the average power actually applied to the load 210.
The systems and methods according to embodiments of the present disclosure minimize these measurement errors by introducing equalizers to equalize the power measurements made in the electrosurgical generator 102 to the actual power applied to the load 210. As shown in
The equalizers 221 are implemented in a digital signal processor (DSP) 220 of the controller 200. The equalizers 221 receive measurements from the sensors 211, 212 and generate an estimated load voltage {circumflex over (V)}load and an estimated load current Îload. The DSP 220 also implements an average estimated power calculator 225 that calculates the average estimated power at the load {circumflex over (P)}avg based on the estimated load voltage {circumflex over (V)}load and the estimated load current Îload. The average estimated power calculator 225 includes a multiplier 224 that multiplies the estimated load voltage {circumflex over (V)}load by the estimated load current Îload and an integrator 226 that integrates the output from the multiplier 224 to obtain the average estimated power at the load {circumflex over (P)}avg.
The DSP 220 communicates the calculated average estimated power at the load {circumflex over (P)}avg to the microprocessor 206, which uses the average estimated power at the load {circumflex over (P)}avg to control the energy conversion circuit 208. For example, the microprocessor 206 may execute a Proportional-Integral-Derivative (PID) control algorithm based on the average estimated power at the load {circumflex over (P)}avg and a desired power level, which may be selected by a user, to determine the amount of electric current that should be supplied by the energy conversion circuit 208 to achieve and maintain the desired power level.
The desired response dk for the LMS adaptation unit 304 may be a pre-computed “pseudo-filter,” or time sequence. The desired response dk may have an idealized magnitude and phase versus frequency response of a converged adaptive filter in the electrosurgical system. For instance, if the converged output current from the system matches the pre-measured magnitude and phase values at one or more frequencies, then this information is used to construct a sequence dk and/or the pseudo-filter.
A desired response sequence dk may be constructed during a calibration process for the electrosurgical generator 102. For a single frequency f1, the calibration process first involves using the RF Output Stage 204 to generate the following test signal:
x(t)=A1 sin(2πf1t).
where the amplitude A1 is a measured or known value. The test signal is applied to a resistive load (e.g., the test resistor 910 of
The desired response sequence dk is formed by sampling a sinusoidal calibration signal d(t) having a known amplitude of excitation or the same amplitude as the test signal x(t) (i.e., A1), but delayed according to a measured or known phase θ1 between the input of the ADCs 215 and the output yk of the adaptive filter (i.e., the combination of the LMS filter 302 and the LMS adaptation unit 304). In other words, the phase θ1 represents the delays introduced by the ADCs 215 and other electronic or digital components disposed between the RF Output Stage 204 and the output yk of the LMS filter 302. Such a calibration signal may be expressed as follows:
d(t)=A1 sin(2πf1t+θ1).
For multiple frequencies fn, where n=1, . . . , N, the calibration process involves using the RF Output Stage 204 to generate the following series of test signals:
xn(t)=An sin(2πfnt),
where n=1, . . . , N and the amplitudes An are measured or known values. The series of test signals are summed together and applied to a resistive load (e.g., the test resistor 910 of
The desired response sequence dk for multiple frequencies is formed by sampling the sum of multiple sinusoidal calibration signals given by the expression:
dn(t)=An sin(2πfnt+θn),
where n=1, . . . , N. The calibration signals dn(t) have known amplitudes of excitation or the same amplitudes as the respective test signals xn(t) (i.e., An), but are delayed according to measured or known phases θn between the input of the ADCs 215 and the output yk of the adaptive filter (i.e., the combination of the LMS filter 302 and the LMS adaptation unit 304).
At the end of adaptation, the estimated phases or delays of the voltage and current will be equal to or approximately equal to each other at desired frequencies of interest, leaving only a difference between the measured phases or delays of the voltage current. Also, the magnitudes of the measured voltage and current will be identical to or approximately identical to the respective magnitudes of the estimated voltage and current.
As shown in
The digital output signal yk is fed back to the LMS weight adaptation unit 304, in which the digital output signal yk is subtracted from the desired response dk by a subtractor 408 to obtain a digital error signal ek. The LMS weight adaptation unit 304 includes an update computation unit 410 that uses the digital error signal ek, the input vector
where μ is chosen by the designer and is bounded by:
The advantage of an equalizer 221 using the LMS filter 302 is that it can accurately equalize the voltage and current measurements at all frequencies of interest. The LMS filter may be trained when the generator is calibrated. The LMS filter 302 may also be trained periodically throughout the life of the electrosurgical generator 102. In some embodiments, once the LMS filter 302 is trained, the LMS weight adaptation unit 304 does not adapt the weight vector
The amplified input signal is then applied to the fractional delay line 504, which may be expressed as z−Δt
The calibration procedure for determining the gain correction factor KCF may involve using a test accessory 905 together with the electrosurgical generator 102 of
The test accessory 905 is used to calibrate the sensors 211, 212 and equalizers 221, 222 for magnitude and phase at one or more frequencies. The calibration process first involves applying the test resistance Rtest of the test accessory 905 across the output terminals 104, 106. The value of the test resistance Rtest is selected to provide minimal phase shift for a nominal voltage and current. Then, the RF Output Stage 204 generates one or more test signals at desired frequencies ωd. Next, a reference voltage magnitude ∥v∥ and a phase angle φv are measured at each of the desired frequencies ωd using the voltage reference meter 201. Also, a reference current magnitude ∥i∥ and phase angle φi are measured at each of the desired frequencies ωd using the current reference meter 202. At the same time, the voltage sensor 211, the current sensor 212, the ADCs 215, and the equalizers 221 produce an estimated voltage magnitude ∥{circumflex over (v)}∥ and phase angle {circumflex over (φ)}v and an estimated current magnitude ∥î∥ and phase angle {circumflex over (φ)}i at each of the desired frequencies ωd of the test signals.
For each desired frequency ωd, the gain correction factors for the voltage and current equalizers KEQ_V(ωd) and KEQ_I(ωd) are calculated according to the following equations:
Then, for each desired frequency ωd, the minimum phases of the equalizers φEQ_V(ωd) and φEQ_I(ωd) are determined such that {circumflex over (φ)}v={circumflex over (φ)}i and φv−φi={circumflex over (φ)}v−{circumflex over (φ)}i. It is desirable to achieve “minimum” phase or delay because the voltage and current measurements are in a closed loop and excessive phase or delay reduces the phase margin or bandwidth of the closed loop.
In step 1008, first magnitude values and first phase angle values of voltage and current components of the test signal are measured at the output terminals. In step 1010, second magnitude values and second phase angle values for the voltage and current components of the test signal are estimated using a first equalizer for the voltage component (e.g., the equalizer 221 of
The fractional delay line 504 of
pr(n)=hLowpass(nM+r),0≤r≤(M−1).
The delay of l is implemented as the initial position of the commutator switch (“l selector”) 614 corresponding to the sample at n=0.
In the Laplacian s-domain, a first-order all-pass filter, which may be used to change delay or phase but not magnitude, is represented by the following transfer function:
The magnitude of the first-order all-pass transfer function is:
and the phase (in radians) is:
where the phase angle is 0 degrees when ωc=0, −90 degrees when ωc=α0, and −180 degrees when ωc>>α0. By fixing ωc, the phase β(ωc) is set by α0. The group delay of the first-order all-pass transfer function is given by:
The first-order all-pass filter is implemented in the digital domain. There are many ways to implement the first-order all-pass filter. One method is to apply the bilinear transform by replacing the Laplacian variable s with
where T is the sample period. Then, the digital all-pass transfer function becomes
This digital all-pass transfer function may be implemented by the following difference equation:
Another method to implement a first-order all-pass filter is to use a simple feedforward/feedback digital comb filter having the following transfer function:
where a is a constant and M is an arbitrary integer delay and M≥0. This transfer function may be implemented by the following difference equation:
y(n)=a·x(n)+x(n−M)−a·y(n−M).
Another type of filter that combines an all-pass delay with a gain is a shelving filter. The shelving filter can be used to perform weighting of certain frequencies while passing other frequencies. The shelving filter can be useful in emphasizing the signal band of interest. A first-order parametric shelving filter transfer function is given by
where A(s) is the first-order all-pass transfer function described above.
To implement a digital shelving filter, the first-order transfer function H(s), which is in the s-domain, is converted to the z-domain. The transfer function H(s) may be converted to the z-domain using the bilinear transform to obtain the following transfer function:
for a frequency response that provides a cut, and
for a frequency response that provides a boost.
The frequency response of the transfer function that provides a cut attenuates a range of frequencies and passes (i.e., applies a gain of 1 to) an adjacent range of frequencies. On the other hand, the frequency response of the transfer function that provides a boost amplifies a range of frequencies and passes an adjacent range of frequencies. The response of the shelving filter may be modified by independently controlling the cutoff/center frequency ωc and the gain V0.
The shelving filter transfer function H(z) may be implemented with the equalizer structures shown in
The equalizer 221 of
Another embodiment of the equalizer 221 may use a peak filter to boost or cut any desired frequency. A second-order peak filter may be implemented with the equalizers 221 of
The center frequency fc of the peak filter is determined by the parameter d, the bandwidth fb is determined by the parameters aB and aC, and the gain is determined by the parameter V0.
Using the equalizers 221 of
Although the illustrative embodiments of the present disclosure have been described herein with reference to the accompanying drawings, it is to be understood that the disclosure is not limited to those precise embodiments, and that various other changes and modifications may be effected therein by one skilled in the art without departing from the scope or spirit of the disclosure.
This application is a divisional of U.S. application Ser. No. 13/085,278 filed on Apr. 12, 2011, now U.S. Pat. No. 8,968,293, the entire content of which is incorporated by reference in this application.
Number | Name | Date | Kind |
---|---|---|---|
2736960 | Armstrong | Mar 1956 | A |
2849788 | Creek | Sep 1958 | A |
3015961 | Roney | Jan 1962 | A |
3513848 | Garvey | May 1970 | A |
3526219 | Balamuth | Sep 1970 | A |
3614484 | Shoh | Oct 1971 | A |
3636943 | Balamuth | Jan 1972 | A |
3648249 | Goldsberry | Mar 1972 | A |
3776238 | Peyman et al. | Dec 1973 | A |
3805787 | Banko | Apr 1974 | A |
3862630 | Balamuth | Jan 1975 | A |
3900823 | Sokal et al. | Aug 1975 | A |
3918442 | Nikolaev et al. | Nov 1975 | A |
3946738 | Newton et al. | Mar 1976 | A |
3955859 | Stella et al. | May 1976 | A |
3956826 | Perdreaux, Jr. | May 1976 | A |
4156187 | Murry et al. | May 1979 | A |
4188927 | Harris | Feb 1980 | A |
4200106 | Douvas et al. | Apr 1980 | A |
4272813 | Howell et al. | Jun 1981 | A |
4319337 | Sander et al. | Mar 1982 | A |
4445063 | Smith | Apr 1984 | A |
4491132 | Aikins | Jan 1985 | A |
4574615 | Bower et al. | Mar 1986 | A |
4617927 | Manes | Oct 1986 | A |
4633119 | Thompson | Dec 1986 | A |
4634420 | Spinosa et al. | Jan 1987 | A |
4640279 | Beard | Feb 1987 | A |
4708127 | Abdelghani | Nov 1987 | A |
4712722 | Hood et al. | Dec 1987 | A |
4827911 | Broadwin et al. | May 1989 | A |
4832683 | Idemoto et al. | May 1989 | A |
4838853 | Parisi | Jun 1989 | A |
4850354 | McGurk-Burleson et al. | Jul 1989 | A |
4865159 | Jamison | Sep 1989 | A |
4896009 | Pawlowski | Jan 1990 | A |
4922902 | Wuchinich et al. | May 1990 | A |
4965532 | Sakurai | Oct 1990 | A |
4981756 | Rhandhawa | Jan 1991 | A |
5026387 | Thomas | Jun 1991 | A |
5112300 | Ureche | May 1992 | A |
5123903 | Quaid et al. | Jun 1992 | A |
5126618 | Takahashi et al. | Jun 1992 | A |
5162044 | Gahn et al. | Nov 1992 | A |
5167725 | Clark et al. | Dec 1992 | A |
D332660 | Rawson et al. | Jan 1993 | S |
5176695 | Dulebohn | Jan 1993 | A |
5184605 | Grzeszykowski | Feb 1993 | A |
5213569 | Davis | May 1993 | A |
5221282 | Wuchinich | Jun 1993 | A |
5226910 | Kajiyama et al. | Jul 1993 | A |
5241236 | Sasaki et al. | Aug 1993 | A |
5257988 | L'Esperance, Jr. | Nov 1993 | A |
5261922 | Hood | Nov 1993 | A |
5263957 | Davison | Nov 1993 | A |
5275609 | Pingleton et al. | Jan 1994 | A |
5282800 | Foshee et al. | Feb 1994 | A |
5304115 | Pflueger et al. | Apr 1994 | A |
D347474 | Olson | May 1994 | S |
5322055 | Davison et al. | Jun 1994 | A |
5324299 | Davison et al. | Jun 1994 | A |
5344420 | Hilal et al. | Sep 1994 | A |
5346502 | Estabrook et al. | Sep 1994 | A |
5366466 | Christian et al. | Nov 1994 | A |
D354564 | Medema | Jan 1995 | S |
5381067 | Greenstein et al. | Jan 1995 | A |
5403312 | Yates et al. | Apr 1995 | A |
5411481 | Allen et al. | May 1995 | A |
5419761 | Narayanan et al. | May 1995 | A |
5421829 | Olichney et al. | Jun 1995 | A |
5449370 | Vaitekunas | Sep 1995 | A |
5483501 | Park et al. | Jan 1996 | A |
5486162 | Brumbach | Jan 1996 | A |
5500216 | Julian et al. | Mar 1996 | A |
5501654 | Failla et al. | Mar 1996 | A |
5505693 | Mackool | Apr 1996 | A |
5562609 | Brumbach | Oct 1996 | A |
5562610 | Brumbach | Oct 1996 | A |
5601601 | Tal et al. | Feb 1997 | A |
5607436 | Pratt et al. | Mar 1997 | A |
5618492 | Auten et al. | Apr 1997 | A |
5628760 | Knoepfler | May 1997 | A |
5630420 | Vaitekunas | May 1997 | A |
D381077 | Hunt | Jul 1997 | S |
5651780 | Jackson et al. | Jul 1997 | A |
5653713 | Michelson | Aug 1997 | A |
5669922 | Hood | Sep 1997 | A |
5674235 | Parisi | Oct 1997 | A |
5690269 | Bolanos et al. | Nov 1997 | A |
5694936 | Fujimoto et al. | Dec 1997 | A |
5713896 | Nardella | Feb 1998 | A |
5733074 | Stock et al. | Mar 1998 | A |
5741226 | Strukel et al. | Apr 1998 | A |
5743900 | Hara | Apr 1998 | A |
5810859 | DiMatteo et al. | Sep 1998 | A |
5827323 | Klieman et al. | Oct 1998 | A |
5828160 | Sugishita | Oct 1998 | A |
5843109 | Mehta et al. | Dec 1998 | A |
5879364 | Bromfield et al. | Mar 1999 | A |
5893835 | Witt et al. | Apr 1999 | A |
5897569 | Kellogg et al. | Apr 1999 | A |
5931835 | Mackey | Aug 1999 | A |
5931836 | Hatta et al. | Aug 1999 | A |
5935143 | Hood | Aug 1999 | A |
5935144 | Estabrook | Aug 1999 | A |
5938633 | Beaupre | Aug 1999 | A |
5944718 | Austin et al. | Aug 1999 | A |
5944737 | Tsonton et al. | Aug 1999 | A |
5954736 | Bishop et al. | Sep 1999 | A |
5954746 | Holthaus et al. | Sep 1999 | A |
5957882 | Nita et al. | Sep 1999 | A |
5957943 | Vaitekunas | Sep 1999 | A |
5968007 | Simon et al. | Oct 1999 | A |
5968060 | Kellogg | Oct 1999 | A |
D416089 | Barton et al. | Nov 1999 | S |
5980510 | Tsonton et al. | Nov 1999 | A |
5989274 | Davison et al. | Nov 1999 | A |
5989275 | Estabrook et al. | Nov 1999 | A |
5993972 | Reich et al. | Nov 1999 | A |
6024741 | Williamson, IV et al. | Feb 2000 | A |
6024750 | Mastri et al. | Feb 2000 | A |
6033375 | Brumbach | Mar 2000 | A |
6036667 | Manna et al. | Mar 2000 | A |
6063098 | Houser et al. | May 2000 | A |
6066132 | Chen et al. | May 2000 | A |
6068647 | Witt et al. | May 2000 | A |
6077285 | Boukhny | Jun 2000 | A |
6083191 | Rose | Jul 2000 | A |
6086584 | Miller | Jul 2000 | A |
6090120 | Wright et al. | Jul 2000 | A |
6109500 | Alli et al. | Aug 2000 | A |
6110127 | Suzuki | Aug 2000 | A |
6113594 | Savage | Sep 2000 | A |
6139320 | Hahn | Oct 2000 | A |
6152902 | Christian et al. | Nov 2000 | A |
6159160 | Hsei et al. | Dec 2000 | A |
6159175 | Strukel et al. | Dec 2000 | A |
6204592 | Hur | Mar 2001 | B1 |
6206844 | Reichel et al. | Mar 2001 | B1 |
6210403 | Klicek | Apr 2001 | B1 |
6214023 | Whipple et al. | Apr 2001 | B1 |
6233476 | Strommer et al. | May 2001 | B1 |
6238366 | Savage et al. | May 2001 | B1 |
D444365 | Bass et al. | Jul 2001 | S |
6254623 | Haibel, Jr. et al. | Jul 2001 | B1 |
6258034 | Hanafy | Jul 2001 | B1 |
6267761 | Ryan | Jul 2001 | B1 |
6270831 | Kumar et al. | Aug 2001 | B2 |
6273852 | Lehe et al. | Aug 2001 | B1 |
6274963 | Estabrook et al. | Aug 2001 | B1 |
6277115 | Saadat | Aug 2001 | B1 |
6278218 | Madan et al. | Aug 2001 | B1 |
6283981 | Beaupre | Sep 2001 | B1 |
6309400 | Beaupre | Oct 2001 | B2 |
6319221 | Savage et al. | Nov 2001 | B1 |
6325811 | Messerly | Dec 2001 | B1 |
6328751 | Beaupre | Dec 2001 | B1 |
6352532 | Kramer et al. | Mar 2002 | B1 |
6379320 | Lafon et al. | Apr 2002 | B1 |
D457958 | Dycus et al. | May 2002 | S |
6383194 | Pothula | May 2002 | B1 |
6387109 | Davison et al. | May 2002 | B1 |
6388657 | Natoli | May 2002 | B1 |
6391042 | Cimino | May 2002 | B1 |
6405733 | Fogarty et al. | Jun 2002 | B1 |
6416486 | Wampler | Jul 2002 | B1 |
6423073 | Bowman | Jul 2002 | B2 |
6423082 | Houser et al. | Jul 2002 | B1 |
6432118 | Messerly | Aug 2002 | B1 |
6436114 | Novak et al. | Aug 2002 | B1 |
6436115 | Beaupre | Aug 2002 | B1 |
6443969 | Novak et al. | Sep 2002 | B1 |
6454781 | Witt et al. | Sep 2002 | B1 |
6454782 | Schwemberger | Sep 2002 | B1 |
6458142 | Faller et al. | Oct 2002 | B1 |
6480796 | Wiener | Nov 2002 | B2 |
6485490 | Wampler et al. | Nov 2002 | B2 |
6491708 | Madan et al. | Dec 2002 | B2 |
6497715 | Satou | Dec 2002 | B2 |
6500176 | Truckai et al. | Dec 2002 | B1 |
6500188 | Harper et al. | Dec 2002 | B2 |
6508815 | Strul et al. | Jan 2003 | B1 |
6524316 | Nicholson et al. | Feb 2003 | B1 |
6533784 | Truckai et al. | Mar 2003 | B2 |
6537291 | Friedman et al. | Mar 2003 | B2 |
6543452 | Lavigne | Apr 2003 | B1 |
6543456 | Freeman | Apr 2003 | B1 |
6544260 | Markel et al. | Apr 2003 | B1 |
6561983 | Cronin et al. | May 2003 | B2 |
6572632 | Zisterer et al. | Jun 2003 | B2 |
6575969 | Rittman, III et al. | Jun 2003 | B1 |
6582451 | Marucci et al. | Jun 2003 | B1 |
6589200 | Schwemberger et al. | Jul 2003 | B1 |
6589239 | Khandkar et al. | Jul 2003 | B2 |
6616450 | Mossle et al. | Sep 2003 | B2 |
6623501 | Heller et al. | Sep 2003 | B2 |
6626926 | Friedman et al. | Sep 2003 | B2 |
6633234 | Wiener et al. | Oct 2003 | B2 |
6656177 | Truckai et al. | Dec 2003 | B2 |
6662127 | Wiener et al. | Dec 2003 | B2 |
6663941 | Brown et al. | Dec 2003 | B2 |
6676660 | Wampler et al. | Jan 2004 | B2 |
6678621 | Wiener et al. | Jan 2004 | B2 |
6679899 | Wiener et al. | Jan 2004 | B2 |
6682544 | Mastri et al. | Jan 2004 | B2 |
6716215 | David et al. | Apr 2004 | B1 |
6731047 | Kauf et al. | May 2004 | B2 |
6733506 | McDevitt et al. | May 2004 | B1 |
6762535 | Take et al. | Jul 2004 | B2 |
6770072 | Truckai et al. | Aug 2004 | B1 |
6773444 | Messerly | Aug 2004 | B2 |
6786382 | Hoffman | Sep 2004 | B1 |
6786383 | Stegelmann | Sep 2004 | B2 |
6790216 | Ishikawa | Sep 2004 | B1 |
6802843 | Truckai et al. | Oct 2004 | B2 |
6828712 | Battaglin et al. | Dec 2004 | B2 |
6869439 | White et al. | Mar 2005 | B2 |
6875220 | Du et al. | Apr 2005 | B2 |
6905497 | Truckai et al. | Jun 2005 | B2 |
6908472 | Wiener et al. | Jun 2005 | B2 |
6913579 | Truckai et al. | Jul 2005 | B2 |
6926716 | Baker et al. | Aug 2005 | B2 |
6929632 | Nita et al. | Aug 2005 | B2 |
6929644 | Truckai et al. | Aug 2005 | B2 |
D509589 | Wells | Sep 2005 | S |
6945981 | Donofrio et al. | Sep 2005 | B2 |
D511145 | Donofrio et al. | Nov 2005 | S |
6976844 | Hickok et al. | Dec 2005 | B2 |
6976969 | Messerly | Dec 2005 | B2 |
6977495 | Donofrio | Dec 2005 | B2 |
6984220 | Wuchinich | Jan 2006 | B2 |
7011657 | Truckai et al. | Mar 2006 | B2 |
7041083 | Chu et al. | May 2006 | B2 |
7041088 | Nawrocki et al. | May 2006 | B2 |
7041102 | Truckai et al. | May 2006 | B2 |
7070597 | Truckai et al. | Jul 2006 | B2 |
7074219 | Levine et al. | Jul 2006 | B2 |
7077039 | Gass et al. | Jul 2006 | B2 |
7077853 | Kramer et al. | Jul 2006 | B2 |
7083619 | Truckai et al. | Aug 2006 | B2 |
7087054 | Truckai et al. | Aug 2006 | B2 |
7108695 | Witt et al. | Sep 2006 | B2 |
7112201 | Truckai et al. | Sep 2006 | B2 |
7118564 | Ritchie et al. | Oct 2006 | B2 |
7124932 | Isaacson et al. | Oct 2006 | B2 |
7125409 | Truckai et al. | Oct 2006 | B2 |
7135018 | Ryan et al. | Nov 2006 | B2 |
7135030 | Schwemberger et al. | Nov 2006 | B2 |
7153315 | Miller | Dec 2006 | B2 |
D536093 | Nakajima et al. | Jan 2007 | S |
7156189 | Bar-Cohen et al. | Jan 2007 | B1 |
7156853 | Muratsu | Jan 2007 | B2 |
7157058 | Marhasin et al. | Jan 2007 | B2 |
7159750 | Racenet et al. | Jan 2007 | B2 |
7163548 | Stulen et al. | Jan 2007 | B2 |
7169146 | Truckai et al. | Jan 2007 | B2 |
7179271 | Friedman et al. | Feb 2007 | B2 |
7186253 | Truckai et al. | Mar 2007 | B2 |
7189233 | Truckai et al. | Mar 2007 | B2 |
7204820 | Akahoshi | Apr 2007 | B2 |
7220951 | Truckai et al. | May 2007 | B2 |
7223229 | Inman et al. | May 2007 | B2 |
7229455 | Sakurai et al. | Jun 2007 | B2 |
7273483 | Wiener et al. | Sep 2007 | B2 |
7300435 | Wham | Nov 2007 | B2 |
7309849 | Truckai et al. | Dec 2007 | B2 |
7311709 | Truckai et al. | Dec 2007 | B2 |
7317955 | McGreevy | Jan 2008 | B2 |
7326236 | Andreas et al. | Feb 2008 | B2 |
7331410 | Yong et al. | Feb 2008 | B2 |
7353068 | Tanaka et al. | Apr 2008 | B2 |
7354440 | Truckal et al. | Apr 2008 | B2 |
7380695 | Doll et al. | Jun 2008 | B2 |
7381209 | Truckai et al. | Jun 2008 | B2 |
7390317 | Taylor et al. | Jun 2008 | B2 |
D574323 | Waaler | Aug 2008 | S |
7407502 | Strul et al. | Aug 2008 | B2 |
7408288 | Hara | Aug 2008 | B2 |
D576725 | Shumer et al. | Sep 2008 | S |
D578643 | Shumer et al. | Oct 2008 | S |
D578644 | Shumer et al. | Oct 2008 | S |
D578645 | Shumer et al. | Oct 2008 | S |
7431704 | Babaev | Oct 2008 | B2 |
7472815 | Shelton, IV et al. | Jan 2009 | B2 |
7479148 | Beaupre | Jan 2009 | B2 |
7479160 | Branch et al. | Jan 2009 | B2 |
7494468 | Rabiner et al. | Feb 2009 | B2 |
7503893 | Kucklick | Mar 2009 | B2 |
7534243 | Chin et al. | May 2009 | B1 |
D594983 | Price et al. | Jun 2009 | S |
7567012 | Namikawa | Jul 2009 | B2 |
D618797 | Price et al. | Jun 2010 | S |
7751115 | Song | Jul 2010 | B2 |
7766905 | Paterson et al. | Aug 2010 | B2 |
7770774 | Mastri et al. | Aug 2010 | B2 |
7780659 | Okada et al. | Aug 2010 | B2 |
D631155 | Peine et al. | Jan 2011 | S |
7876030 | Taki et al. | Jan 2011 | B2 |
D631965 | Price et al. | Feb 2011 | S |
7892606 | Thies et al. | Feb 2011 | B2 |
7901423 | Stulen et al. | Mar 2011 | B2 |
7959050 | Smith et al. | Jun 2011 | B2 |
7959626 | Hong et al. | Jun 2011 | B2 |
7976544 | McClurken et al. | Jul 2011 | B2 |
8057498 | Robertson | Nov 2011 | B2 |
8058771 | Giordano et al. | Nov 2011 | B2 |
8617154 | Johnston | Dec 2013 | B2 |
8623007 | Deborski et al. | Jan 2014 | B2 |
8636730 | Keppel | Jan 2014 | B2 |
8641712 | Couture | Feb 2014 | B2 |
8668690 | Couture | Mar 2014 | B2 |
8745846 | Behnke, II et al. | Jun 2014 | B2 |
8888783 | Young | Nov 2014 | B2 |
8944834 | Plaven et al. | Feb 2015 | B2 |
8968293 | Gilbert | Mar 2015 | B2 |
8968297 | Collins | Mar 2015 | B2 |
9023025 | Behnke, II et al. | May 2015 | B2 |
9028479 | Orszulak | May 2015 | B2 |
9028481 | Behnke, II | May 2015 | B2 |
9033970 | Behnke, II et al. | May 2015 | B2 |
9033973 | Krapohl et al. | May 2015 | B2 |
9039692 | Behnke, II et al. | May 2015 | B2 |
9039693 | Behnke, II et al. | May 2015 | B2 |
20010025184 | Messerly | Sep 2001 | A1 |
20010031950 | Ryan | Oct 2001 | A1 |
20010039419 | Francischelli et al. | Nov 2001 | A1 |
20020002377 | Cimino | Jan 2002 | A1 |
20020019649 | Sikora et al. | Feb 2002 | A1 |
20020022836 | Goble et al. | Feb 2002 | A1 |
20020077550 | Rabiner et al. | Jun 2002 | A1 |
20020156493 | Houser et al. | Oct 2002 | A1 |
20030055443 | Spotnitz | Mar 2003 | A1 |
20030204199 | Novak et al. | Oct 2003 | A1 |
20030212332 | Fenton et al. | Nov 2003 | A1 |
20040030254 | Babaev | Feb 2004 | A1 |
20040047485 | Sherrit et al. | Mar 2004 | A1 |
20040092921 | Kadziauskas et al. | May 2004 | A1 |
20040097919 | Wellman et al. | May 2004 | A1 |
20040097996 | Rabiner et al. | May 2004 | A1 |
20040167508 | Wham et al. | Aug 2004 | A1 |
20040193666 | Christoph | Sep 2004 | A1 |
20040199193 | Hayashi et al. | Oct 2004 | A1 |
20040204728 | Haefner | Oct 2004 | A1 |
20040243157 | Connor et al. | Dec 2004 | A1 |
20040260300 | Gorensek et al. | Dec 2004 | A1 |
20050033337 | Muir et al. | Feb 2005 | A1 |
20050049546 | Messerly et al. | Mar 2005 | A1 |
20050113819 | Wham et al. | May 2005 | A1 |
20050143769 | White et al. | Jun 2005 | A1 |
20050149108 | Cox | Jul 2005 | A1 |
20050165345 | Laufer et al. | Jul 2005 | A1 |
20050177184 | Easley | Aug 2005 | A1 |
20050182398 | Paterson | Aug 2005 | A1 |
20050192610 | Houser et al. | Sep 2005 | A1 |
20050209620 | Du et al. | Sep 2005 | A1 |
20050261581 | Hughes et al. | Nov 2005 | A1 |
20050261588 | Makin et al. | Nov 2005 | A1 |
20050288659 | Kimura et al. | Dec 2005 | A1 |
20060030797 | Zhou et al. | Feb 2006 | A1 |
20060063130 | Hayman et al. | Mar 2006 | A1 |
20060079878 | Houser | Apr 2006 | A1 |
20060084963 | Messerly | Apr 2006 | A1 |
20060190034 | Nishizawa et al. | Aug 2006 | A1 |
20060211943 | Beaupre | Sep 2006 | A1 |
20060232471 | Coumou | Oct 2006 | A1 |
20060235306 | Cotter et al. | Oct 2006 | A1 |
20060253050 | Yoshimine et al. | Nov 2006 | A1 |
20070016235 | Tanaka et al. | Jan 2007 | A1 |
20070016236 | Beaupre | Jan 2007 | A1 |
20070055228 | Berg et al. | Mar 2007 | A1 |
20070060915 | Kucklick | Mar 2007 | A1 |
20070063618 | Bromfield | Mar 2007 | A1 |
20070129716 | Daw et al. | Jun 2007 | A1 |
20070130771 | Ehlert et al. | Jun 2007 | A1 |
20070131034 | Ehlert et al. | Jun 2007 | A1 |
20070149881 | Rabin | Jun 2007 | A1 |
20070162050 | Sartor | Jul 2007 | A1 |
20070173872 | Neuenfeldt | Jul 2007 | A1 |
20070185380 | Kucklick | Aug 2007 | A1 |
20070219481 | Babaev | Sep 2007 | A1 |
20070249941 | Salehi et al. | Oct 2007 | A1 |
20070260234 | McCullagh et al. | Nov 2007 | A1 |
20070265560 | Soltani et al. | Nov 2007 | A1 |
20070275348 | Lemon | Nov 2007 | A1 |
20070282335 | Young et al. | Dec 2007 | A1 |
20070287933 | Phan et al. | Dec 2007 | A1 |
20080009848 | Paraschiv et al. | Jan 2008 | A1 |
20080058585 | Novak et al. | Mar 2008 | A1 |
20080058775 | Darian et al. | Mar 2008 | A1 |
20080058845 | Shimizu et al. | Mar 2008 | A1 |
20080082039 | Babaev | Apr 2008 | A1 |
20080082098 | Tanaka et al. | Apr 2008 | A1 |
20080172051 | Masuda et al. | Jul 2008 | A1 |
20080177268 | Daum et al. | Jul 2008 | A1 |
20080200940 | Eichmann et al. | Aug 2008 | A1 |
20080208231 | Ota et al. | Aug 2008 | A1 |
20080234708 | Houser et al. | Sep 2008 | A1 |
20080234709 | Houser | Sep 2008 | A1 |
20080234710 | Neurohr et al. | Sep 2008 | A1 |
20080234711 | Houser et al. | Sep 2008 | A1 |
20080262490 | Williams | Oct 2008 | A1 |
20080281200 | Voic et al. | Nov 2008 | A1 |
20080287948 | Newton et al. | Nov 2008 | A1 |
20090030311 | Stulen et al. | Jan 2009 | A1 |
20090030351 | Wiener et al. | Jan 2009 | A1 |
20090030437 | Houser et al. | Jan 2009 | A1 |
20090030438 | Stulen | Jan 2009 | A1 |
20090030439 | Stulen | Jan 2009 | A1 |
20090036911 | Stulen | Feb 2009 | A1 |
20090036912 | Wiener et al. | Feb 2009 | A1 |
20090036913 | Wiener et al. | Feb 2009 | A1 |
20090036914 | Houser | Feb 2009 | A1 |
20090076506 | Baker | Mar 2009 | A1 |
20090082716 | Akahoshi | Mar 2009 | A1 |
20090105750 | Price et al. | Apr 2009 | A1 |
20090112204 | Aronow et al. | Apr 2009 | A1 |
20090118802 | Mioduski et al. | May 2009 | A1 |
20090143806 | Witt et al. | Jun 2009 | A1 |
20090270853 | Yachi et al. | Oct 2009 | A1 |
20100036370 | Mirel et al. | Feb 2010 | A1 |
20100036405 | Giordano et al. | Feb 2010 | A1 |
20100158307 | Kubota et al. | Jun 2010 | A1 |
20100179577 | Houser | Jul 2010 | A1 |
20100187283 | Crainich et al. | Jul 2010 | A1 |
20100298743 | Nield et al. | Nov 2010 | A1 |
20100298851 | Nield | Nov 2010 | A1 |
20100331869 | Voegele et al. | Dec 2010 | A1 |
20100331870 | Wan et al. | Dec 2010 | A1 |
20100331871 | Nield et al. | Dec 2010 | A1 |
20100331872 | Houser et al. | Dec 2010 | A1 |
20110009850 | Main et al. | Jan 2011 | A1 |
20110015627 | DiNardo et al. | Jan 2011 | A1 |
20110015631 | Wiener et al. | Jan 2011 | A1 |
20110015660 | Wiener et al. | Jan 2011 | A1 |
20110082486 | Messerly et al. | Apr 2011 | A1 |
20110087212 | Aldridge et al. | Apr 2011 | A1 |
20110087213 | Messerly et al. | Apr 2011 | A1 |
20110087214 | Giordano et al. | Apr 2011 | A1 |
20110087215 | Aldridge et al. | Apr 2011 | A1 |
20110087216 | Aldridge et al. | Apr 2011 | A1 |
20110087217 | Yates et al. | Apr 2011 | A1 |
20110087218 | Boudreaux et al. | Apr 2011 | A1 |
20110087256 | Wiener et al. | Apr 2011 | A1 |
20110092972 | Allen | Apr 2011 | A1 |
20110125175 | Stulen et al. | May 2011 | A1 |
20110196286 | Robertson et al. | Aug 2011 | A1 |
20110196287 | Robertson et al. | Aug 2011 | A1 |
20110196398 | Robertson et al. | Aug 2011 | A1 |
20110196399 | Robertson et al. | Aug 2011 | A1 |
20110196400 | Robertson et al. | Aug 2011 | A1 |
20110196401 | Robertson et al. | Aug 2011 | A1 |
20110196402 | Robertson et al. | Aug 2011 | A1 |
20110196403 | Robertson et al. | Aug 2011 | A1 |
20110196404 | Dietz et al. | Aug 2011 | A1 |
20110196405 | Dietz | Aug 2011 | A1 |
20110288452 | Houser et al. | Nov 2011 | A1 |
20120022521 | Odom et al. | Jan 2012 | A1 |
20120029546 | Robertson | Feb 2012 | A1 |
20120220997 | Johnston | Aug 2012 | A1 |
20120239020 | Cunningham | Sep 2012 | A1 |
20120239025 | Smith | Sep 2012 | A1 |
20120239026 | Orszulak et al. | Sep 2012 | A1 |
20120265194 | Podhajsky | Oct 2012 | A1 |
20120310241 | Orszulak | Dec 2012 | A1 |
20130023867 | Collins | Jan 2013 | A1 |
20130066311 | Smith et al. | Mar 2013 | A1 |
20130079763 | Heckel et al. | Mar 2013 | A1 |
Number | Date | Country |
---|---|---|
1634601 | Jul 2005 | CN |
1640365 | Jul 2005 | CN |
1694649 | Nov 2005 | CN |
1922563 | Feb 2007 | CN |
101040799 | Sep 2007 | CN |
179607 | Mar 1905 | DE |
390937 | Mar 1924 | DE |
1099658 | Feb 1961 | DE |
1139927 | Nov 1962 | DE |
1149832 | Jun 1963 | DE |
1439302 | Jan 1969 | DE |
2439587 | Feb 1975 | DE |
2455174 | May 1975 | DE |
2407559 | Aug 1975 | DE |
2602517 | Jul 1976 | DE |
2504280 | Aug 1976 | DE |
2540968 | Mar 1977 | DE |
2820908 | Nov 1978 | DE |
2803275 | Aug 1979 | DE |
2823291 | Nov 1979 | DE |
2946728 | May 1981 | DE |
3143421 | May 1982 | DE |
3045996 | Jul 1982 | DE |
3120102 | Dec 1982 | DE |
3510586 | Oct 1986 | DE |
3604823 | Aug 1987 | DE |
3904558 | Aug 1990 | DE |
3942998 | Jul 1991 | DE |
4206433 | Sep 1993 | DE |
4339049 | May 1995 | DE |
19506363 | Aug 1996 | DE |
19717411 | Nov 1998 | DE |
19848540 | May 2000 | DE |
171967 | Feb 1986 | EP |
0 246 350 | Nov 1987 | EP |
267403 | May 1988 | EP |
296777 | Dec 1988 | EP |
310431 | Apr 1989 | EP |
325456 | Jul 1989 | EP |
336742 | Oct 1989 | EP |
390937 | Oct 1990 | EP |
443256 | Aug 1991 | EP |
456470 | Nov 1991 | EP |
482195 | Apr 1992 | EP |
0 556 705 | Aug 1993 | EP |
608609 | Aug 1994 | EP |
612570 | Aug 1994 | EP |
0 836 868 | Apr 1998 | EP |
880220 | Nov 1998 | EP |
0 882 955 | Dec 1998 | EP |
908148 | Apr 1999 | EP |
908155 | Apr 1999 | EP |
1051948 | Nov 2000 | EP |
1157667 | Nov 2001 | EP |
1199044 | Apr 2002 | EP |
1366724 | Dec 2003 | EP |
1776929 | Apr 2007 | EP |
1832259 | Sep 2007 | EP |
1844720 | Oct 2007 | EP |
1862133 | Dec 2007 | EP |
1974771 | Oct 2008 | EP |
2074959 | Jul 2009 | EP |
2301463 | Mar 2011 | EP |
2648233 | Oct 2013 | EP |
1 275 415 | Nov 1961 | FR |
1 347 865 | Jan 1964 | FR |
2 313 708 | Dec 1976 | FR |
2364461 | Apr 1978 | FR |
2 502 935 | Oct 1982 | FR |
2 517 953 | Jun 1983 | FR |
2 573 301 | May 1986 | FR |
2032221 | Apr 1980 | GB |
2447767 | Sep 2008 | GB |
S59193635 | Nov 1984 | JP |
H1024048 | Jan 1998 | JP |
2001508959 | Jul 2001 | JP |
2003258606 | Sep 2003 | JP |
2008086776 | Apr 2008 | JP |
201028795 | Feb 2010 | JP |
166452 | Jan 1965 | SU |
727201 | Apr 1980 | SU |
9222259 | Dec 1992 | WO |
9314708 | Aug 1993 | WO |
9837815 | Sep 1998 | WO |
0154590 | Aug 2001 | WO |
0211634 | Feb 2002 | WO |
0245589 | Jun 2002 | WO |
03090635 | Nov 2003 | WO |
2005122917 | Dec 2005 | WO |
2006042210 | Apr 2006 | WO |
06050888 | May 2006 | WO |
2006058223 | Jun 2006 | WO |
2006129465 | Dec 2006 | WO |
2007047531 | Apr 2007 | WO |
2007143665 | Dec 2007 | WO |
2008016886 | Feb 2008 | WO |
08053532 | May 2008 | WO |
2008130793 | Oct 2008 | WO |
2009018406 | Feb 2009 | WO |
2009027065 | Mar 2009 | WO |
2010120944 | Oct 2010 | WO |
2013150477 | Oct 2013 | WO |
Entry |
---|
International Search Report EP10180965.5 dated Jan. 26, 2011. |
International Search Report EP10181018.2 dated Jan. 26, 2011. |
International Search Report EP10181060.4 dated Jan. 26, 2011. |
International Search Report EP10182003.3 dated Dec. 28, 2010. |
International Search Report EP10182005.8 dated Jan. 5, 2011. |
International Search Report EP10188190.2 dated Nov. 22, 2010. |
International Search Report EP10191319.2 dated Feb. 22, 2011. |
International Search Report EP10195393.3 dated Apr. 11, 2011. |
International Search Report EP11155959.7 dated Jun. 30, 2011. |
International Search Report EP11155960.5 dated Jun. 10, 2011. |
International Search Report PCT/US03/33711 dated Jul. 16, 2004. |
International Search Report PCT/US03/33832 dated Jun. 17, 2004. |
International Search Report PCT/US03/37110 dated Jul. 25, 2005. |
International Search Report PCT/US03/37310 dated Aug. 13, 2004. |
International Search Report PCT/US04/02961 dated Aug. 2, 2005. |
International Search Report PCT/US04/13443 dated Dec. 10, 2004. |
International Search Report PCT/US08/052460 dated Apr. 24, 2008. |
International Search Report PCT/US09/46870 dated Jul. 21, 2009. |
European Search Report issued in corresponding EP Application No. 14169809.2 dated Aug. 29, 2014. |
U. Zolzer, “Equalizers”, Digital Audio Signal Processing, John Wiley and Sons, 1997, 19 pp. |
B. Widrow and S. Stearns, “Inverse Adaptive Modeling, Equalization, and Deconvolution,” Prentice-Hall, 1985, 6 pp. |
A. Williams and F. Taylor, “Networks for the Time Domain”, Electronic Filter Design Handbook: LC, Active, and Digital Filters, 2nd Edition, McGraw-Hill, 1988, 4 pp. |
European Search Report issued in corresponding EP Application No. 12163969.4 dated Jul. 16, 2012. |
Wald et al., “Accidental Burns”, JAMA, Aug. 16, 1971, vol. 217, No. 7, pp. 916-921. |
Vallfors et al., “Automatically Controlled Bipolar Electrosoagulation—'COA-COMP” Neurosurgical Review 7:2-3 (1984) pp. 187-190. |
Sugita et al., “Bipolar Coagulator with Automatic Thermocontrol” J. Neurosurg., vol. 41, Dec. 1944, pp. 777-779. |
Prutchi et al. “Design and Development of Medical Electronic Instrumentation”, John Wiley & Sons, Inc. 2005. |
Muller et al. “Extended Left Hemicolectomy Using the LigaSure Vessel Sealing System” Innovation That Work; Company Newsletter; Sep. 1999. |
Ogden Goertzel Alternative to the Fourier Transform: Jun. 1993 pp. 485-487 Electronics World; Reed Business Publishing, Sutton, Surrey, BG vol. 99, No. 9. 1687. |
Hadley I C D et al., “Inexpensive Digital Thermometer for Measurements on Semiconductors” International Journal of Electronics; Taylor and Francis. Ltd.; London, GB; vol. 70, No. 6 Jun. 1, 1991; pp. 1155-1162. |
Burdette et al. “In Vivo Probe Measurement Technique for Determining Dielectric Properties at VHF Through Microwave Frequencies”, IEEE Transactions on Microwave Theory and Techniques, vol. MTT-28, No. 4, Apr. 1980 pp. 414-427. |
Richard Wolf Medical Instruments Corp. Brochure, “Kleppinger Bipolar Forceps & Bipolar Generator” 3 pp. Jan. 1989. |
Astrahan, “A Localized Current Field Hyperthermia System for Use with 192-Iridium Interstitial Implants” Medical Physics, 9 (3), May/Jun. 1982. |
Alexander et al., “Magnetic Resonance Image-Directed Stereotactic Neurosurgery: Use of Image Fusion with Computerized Tomography to Enhance Spatial Accuracy” Journal Neurosurgery, 83; (1995) pp. 271-276. |
Geddes et al., “The Measurement of Physiologic Events by Electrical Impedence” Am. J. MI, Jan. Mar. 1964, pp. 16-27. |
Cosman et al., “Methods of Making Nervous System Lesions” In William RH, Rengachary SS (eds): Neurosurgery, New York: McGraw-Hill, vol. 111, (1984), pp. 2490-2499. |
Anderson et al., “A Numerical Study of Rapid Heating for High Temperature Radio Frequency Hyperthermia” International Journal of Bio-Medical Computing, 35 (1994) pp. 297-307. |
Benaron et al., “Optical Time-of-Flight and Absorbance Imaging of Biologic Media”, Science, American Association for the Advancement of Science, Washington, DC, vol. 259, Mar. 5, 1993, pp. 1463-1466. |
Cosman et al., “Radiofrequency Lesion Generation and Its Effect on Tissue Impedance” Applied Neurophysiology 51: (1988) pp. 230-242. |
Ni W. et al. “A Signal Processing Method for the Coriolis Mass Flowmeter Based on a Normalized . . . ” Journal of Applied Sciences—Yingyong Kexue Xuebao, Shangha CN, vol. 23 No. 2;(Mar. 2005); pp. 160-164. |
Chicharo et al. “A Sliding Goertzel Algorith” Aug. 1996, pp. 283-297 Signal Processing, Elsevier Science Publishers B.V. Amsterdam, NL vol. 52 No. 3. |
Bergdahl et al., “Studies on Coagulation and the Development of an Automatic Computerized Bipolar Coagulator” Journal of Neurosurgery 75:1, (Jul. 1991) pp. 148-151. |
Cosman et al., “Theoretical Aspects of Radiofrequency Lesions in the Dorsal Root Entry Zone” Neurosurgery 15:(1984) pp. 945-950. |
Goldberg et al., “Tissue Ablation with Radiofrequency: Effect of Probe Size, Gauge, Duration, and Temperature on Lesion Volume” Acad Radio (1995) vol. 2, No. 5, pp. 399-404. |
Medtrex Brochure—Total Control at Full Speed, “The O.R. Pro 300” 1 p. Sep. 1998. |
Valleylab Brochure “Valleylab Electroshield Monitoring System” 2 pp. Nov. 1995. |
International Search Report EP 98300964.8 dated Dec. 4, 2000. |
International Search Report EP 04009964 dated Jul. 13, 2004. |
International Search Report EP 04011375 dated Sep. 10, 2004. |
International Search Report EP 04015981.6 dated Sep. 29, 2004. |
International Search Report EP04707738 dated Jul. 4, 2007. |
International Search Report EP 05002769.7 dated Jun. 9, 2006. |
International Search Report EP 05014156.3 dated Dec. 28, 2005. |
International Search Report EP05021944.3 dated Jan. 18, 2006. |
International Search Report EP 05022350.2 dated Jan. 18, 2006. |
International Search Report EP 06000708.5 dated Apr. 21, 2006. |
International Search Report—extended EP 06000708.5 dated Aug. 22, 2006. |
International Search Report EP 06006717.0 dated Aug. 7, 2006. |
International Search Report EP 06010499.9 dated Jan. 29, 2008. |
International Search Report EP 06022028.2 dated Feb. 5, 2007. |
International Search Report EP 06025700.3 dated Apr. 12, 2007. |
International Search Report EP 07001481.6 dated Apr. 23, 2007. |
International Search Report EP 07001484.0 dated Jun. 14, 2010. |
International Search Report EP 07001485.7 dated May 15, 2007. |
International Search Report EP 07001489.9 dated Dec. 20, 2007. |
International Search Report EP 07001491 dated Jun. 6, 2007. |
International Search Report EP 07001494.9 dated Aug. 25, 2010. |
International Search Report EP 07001494.9 extended dated Mar. 7, 2011. |
Japanese Office Action issued in corresponding JP application No. 2012-088062 dated Dec. 1, 2015. |
Japanese Office Action issued in corresponding application No. 2012-088062 dated Mar. 22, 2016. |
European Office Action issue in corresponding application No. 14 169 809.2 dated Jul. 14, 2016, 4 pages. |
Japanese Office Action with English translation, issued in corresponding Application No. 2016-142394 dated Apr. 18, 2017, 13 pages. |
International Search Report EP 07001527.6 dated May 9, 2007. |
International Search Report EP 07004355.9 dated May 21, 2007. |
International Search Report EP 07008207.8 dated Sep. 13, 2007. |
International Search Report EP 07009322.4 dated Jan. 14, 2008. |
International Search Report EP 07010673.7 dated Sep. 24, 2007. |
International Search Report EP 07015601.3 dated Jan. 4, 2008. |
International Search Report EP 07015602.1 dated Dec. 20, 2007. |
International Search Report EP 07019174.7 dated Jan. 29, 2008. |
International Search Report EP08004667.5 dated Jun. 3, 2008. |
International Search Report EP08006733.3 dated Jul. 28, 2008. |
International Search Report EP08012503 dated Sep. 19, 2008. |
International Search Report EP08013605 dated Feb. 25, 2009. |
International Search Report EP08015601.1 dated Dec. 5, 2008. |
International Search Report EP08155780 dated Jan. 19, 2009. |
International Search Report EP08016540.0 dated Feb. 25, 2009. |
International Search Report EP08166208.2 dated Dec. 1, 2008. |
International Search Report EP09003678.1 dated Aug. 7, 2009. |
International Search Report EP09004250.8 dated Aug. 2, 2010. |
International Search Report EP09005160.8 dated Aug. 27, 2009. |
International Search Report EP09009860 dated Dec. 8, 2009. |
International Search Report EP09012386 dated Apr. 1, 2010. |
International Search Report EP09012388.6 dated Apr. 13, 2010. |
International Search Report EP09012389.4 dated Jul. 6, 2010. |
International Search Report EP09012391.0 dated Apr. 19, 2010. |
International Search Report EP09012392 dated Mar. 30, 2010. |
International Search Report EP09012396 dated Apr. 7, 2010. |
International Search Report EP09012400 dated Apr. 7, 2010. |
International Search Report EP09156861.8 dated Jul. 14, 2009. |
International Search Report EP09158915 dated Jul. 14, 2009. |
International Search Report EP09164754.5 dated Aug. 21, 2009. |
International Search Report EP09169377.0 dated Dec. 15, 2009. |
International Search Report EP09169588.2 dated Mar. 2, 2010. |
International Search Report EP09169589.0 dated Mar. 2, 2010. |
International Search Report EP09172749.5 dated Dec. 4, 2009. |
International Search Report EP10001808.4 dated Jun. 21, 2010. |
International Search Report EP10150563.4 dated Jun. 10, 2010. |
International Search Report EP10150564.2 dated Mar. 29, 2010. |
International Search Report EP10150565.9 dated Mar. 12, 2010. |
International Search Report EP10150566.7 dated Jun. 10, 2010. |
International Search Report EP10150567.5 dated Jun. 10, 2010. |
International Search Report EP10164740.2 dated Aug. 3, 2010. |
International Search Report EP10171787.4 dated Nov. 18, 2010. |
International Search Report EP10172636.2 dated Dec. 6, 2010. |
International Search Report EP10174476.1 dated Nov. 12, 2010. |
International Search Report EP10178287.8 dated Dec. 14, 2010. |
International Search Report EP10179321.4 dated Mar. 18, 2011. |
International Search Report EP10179353.7 dated Dec. 21, 2010. |
International Search Report EP10179363.6 dated Jan. 12, 2011. |
International Search Report EP10180004.3 dated Jan. 5, 2011. |
International Search Report EP10180964.8 dated Dec. 22, 2010. |
European Examination Report issued in corresponding EP Application No. 14169809.2 dated Aug. 21, 2015. |
Number | Date | Country | |
---|---|---|---|
20150164576 A1 | Jun 2015 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 13085278 | Apr 2011 | US |
Child | 14636422 | US |