Radio-frequency (RF) powered implantable stimulators and battery powered implantable stimulators are described in the art. See, for instance, U.S. Pat. No. 5,193,539 (“Implantable Microstimulator); U.S. Pat. No. 5,193,540 (“Structure and Method of Manufacture of an Implantable Microstimulator”); U.S. Pat. No. 5,312,439 (“Implantable Device Having an Electrolytic Storage Electrode”); U.S. Pat. No. 6,185,452 (“Battery-Powered Patient Implantable Device”); U.S. Pat. Nos. 6,164,284 and 6,208,894 (both titled “System of Implantable Device for Monitoring and/or Affecting Body Parameters”). Each of these patents is incorporated herein by reference in its respective entirety.
Implantable stimulators configured to prevent or treat various disorders associated with prolonged inactivity, confinement or immobilization of one or more muscles are taught, e.g., in U.S. Pat. No. 6,061,596 (“Method for Conditioning Pelvis Musculature Using an Implanted Microstimulator”); U.S. Pat. No. 6,051,017 (“Implantable Microstimulator and Systems Employing the Same”); U.S. Pat. No. 6,175,764 (“Implantable Microstimulator System for Producing Repeatable Patterns of Electrical Stimulation”); U.S. Pat. No. 6,181,965 (“Implantable Microstimulator System for Prevention of Disorders”); U.S. Pat. No. 6,185,455 (“Methods of Reducing the Incidence of Medical Complications Using Implantable Microstimulators”); and U.S. Pat. No. 6,214,032 (“System for Implanting a Microstimulator”). Each of these patents is incorporated herein by reference in its respective entirety.
A typical implantable stimulator is intended to permanently remain in the body of a patient once it is implanted. Hence, transcutaneous communication between an implantable stimulator and an external device is important for the stimulator to function properly. For example, communication with the implantable stimulator may be effected to perform a number of functions including, but not limited to, transferring power to the stimulator, transferring data to and from the stimulator, programming the stimulator, and monitoring the stimulator's various functions.
An exemplary system for communicating with an implantable stimulator includes a coil configured to transmit a signal modulated with on-off keying (OOK) modulation to transmit control data. The exemplary system further includes a first telemetry receiver in the implantable stimulator configured to receive the control data in accordance with the OOK modulation.
An exemplary method of communicating with an implantable stimulator includes modulating a signal with control data using on-off keying (OOK) modulation and transmitting the signal to the implantable stimulator.
The accompanying drawings illustrate various embodiments of the present invention and are a part of the specification. The illustrated embodiments are merely examples of the present invention and do not limit the scope of the invention.
Throughout the drawings, identical reference numbers designate similar, but not necessarily identical, elements.
Several types of implantable stimulators and external devices utilize a magnetic field to achieve transcutaneous communication via a bidirectional telemetry link. An implantable stimulator and an external device typically both have an RF coil that is used as the transmitter and receiver of the magnetic field. Accurate communication between an implantable stimulator and an external device typically requires a precise reference clock within the implantable stimulator. The reference clock allows timing synchronization in the transmission of data to and from the implantable stimulator so that the implantable stimulator may demodulate data that has been modulated by the external device.
Many implantable stimulators include a precision circuit configured to provide the precise reference clock. The precision circuit may require calibration data for the reference clock to be synchronized with the frequency of the transmitting coil of the external device. This calibration data may be transmitted by the external device via the bidirectional telemetry link. However, in some instances, the bidirectional telemetry link may fail due to a number of factors including, but not limited to, a loss of battery power in the stimulator, interference, and/or coil malfunction. Without a functioning telemetry link between the external device and the implantable stimulator, important control data such as, but not limited to, the calibration data may not be transmitted to the implantable stimulator.
Hence, systems and methods for communicating with an implantable stimulator are described herein. A coil may be configured to transmit a signal including control data in accordance with a first telemetry scheme or a second telemetry scheme to an implantable stimulator. The implantable stimulator may include a first telemetry receiver for receiving the control data in accordance with the first telemetry scheme and a second telemetry receiver for receiving the control data in accordance with the second telemetry scheme. In some embodiments, the first telemetry scheme includes frequency shift keying (FSK) modulation and the second telemetry scheme includes on-off keying (OOK) modulation.
In the following description, for purposes of explanation, numerous specific details are set forth in order to provide a thorough understanding of the present system and method. It will be apparent, however, to one skilled in the art that the present system and method may be practiced without these specific details. Reference in the specification to “one embodiment” or “an embodiment” means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. The appearance of the phrase “in one embodiment” in various places in the specification are not necessarily all referring to the same embodiment.
The implantable stimulator (10) may be implanted in the target tissue area of a patient and the external device (20) may be used to communicate with and/or transfer power to the stimulator (10). Such communication and/or power transfer may include, but is not limited to, transcutaneously transmitting data to the stimulator (10), receiving data from the stimulator (10), transferring power to a battery (16) in the stimulator (10), and/or providing recovery power to the battery (16) when the battery has been depleted to zero volts.
As illustrated in
The functions performed by the external device (20) will vary as best serves the particular application of the stimulator (10). The shape and design of the external device (20) will likewise vary. The external device (20) may be embodied by the external components (20) shown in
The exemplary external device (20) of
The external device (20) may be configured to perform any number of functions via the bidirectional telemetry link (48) and/or the forward telemetry link (38). For example, the external device (20) may be configured to transcutaneously charge the rechargeable battery (16) in the implanted stimulator (10). The external device (20) may also be configured to transcutaneously transmit data to the stimulator (10), receive data from the stimulator (10), and/or provide recovery power to the rechargeable battery (16) when the battery (16) has been depleted to zero volts. The transmitted data may include configuration bits, programming bits, calibration bits, and/or other types of data.
The RF signal may be sent by the external device (20), for example, and may include a carrier signal having modulated control data. The receiver (42) may then rectify the carrier signal to provide charging power for the rechargeable battery (16) and demodulate the carrier signal to extract the control data. As used herein and in the appended claims, the terms “control data” or “control bits” will be used to refer to any data or bits that are transmitted from the external device (20) to the implantable stimulator (10) or from the implantable stimulator (10) to the external device (20). For example, the control data may include, but is not limited to, calibration data used by a reference clock generation circuit (56) and programming data used by a control circuit (58).
As shown in
In some embodiments, the coil (18) may also be connected to a back telemetry circuit (54) to allow telemetry data to be sent from the stimulator (10) to the external device (20). The back telemetry circuit (54) may be any circuit configured to transmit data. The coil (18) may also be connected to an OOK receiver (43) to receive OOK modulated data. The OOK receiver (43) may be any circuit configured to receive and process an RF signal that has been OOK modulated. For example, the OOK receiver (43) may be a microprocessor, DSP, ASIC, processor with firmware, FPGA, or any other combination of hardware and/or software. Furthermore, the OOK receiver (43) may be integrated into the receiver (42). The function of the OOK receiver (43) will be described in more detail below.
Referring to
The reference clock generation circuit (56) and the clock generation circuit (55) are illustrated as separate components within the stimulator (10). However, it will be understood that the reference clock generation circuit (56) and/or the clock generation circuit (55) may be integrated into a single component, integrated into the control circuit (58), or integrated into any other circuitry included in the stimulator (10).
In some embodiments, the reference clock generation circuit (56) requires calibration data to synchronize the frequency of the reference clock signal with the frequency used by the external device (20) to generate the RF signal. This calibration data may be periodically sent, for example, from the external device (20) via the bidirectional telemetry link (48). However, if the bidirectional telemetry link (48) is disabled for any of a number of reasons, some of which will be described in detail below, the calibration data may not be conveyed to the reference clock generation circuit (56) resulting in a reference clock (ref clk) that is not synchronized with the frequency used by the external device (20). As will be described in more detail below, the frequency independent OOK telemetry link (38) may then be used to transmit the calibration data to the reference clock generation circuit (56). The calibration data may then be used to resynchronize the reference clock (ref clk) with the frequency used by the external device (20) such that the bidirectional telemetry link (48) may again be used to transmit control data and/or transfer power from the external device (20) to the stimulator (10).
The implantable stimulator (10) of
The stimulator (10) may also operate in storage mode to conserve power. In storage mode, the stimulator (10) disables all circuitry except for circuitry that is used to recharge the battery (16) and circuitry used to listen for and receive an OOK telemetry signal via the forward telemetry link (38).
Hence, the OOK telemetry link (38) allows the external device (20) to communicate with the stimulator (10) even when the stimulator (10) is not actively listening for an RF signal to be transmitted via the bidirectional telemetry link (48), e.g., when the stimulator (10) is operating in the hibernation state or in the storage state. The OOK telemetry link (38) also provides a communication interface between the external device (20) and the stimulator (10) that may be used in emergency situations, e.g., when the bidirectional telemetry link (48) fails or when there is an emergency power shutdown.
The second signal (131) of
Thus, as illustrated in
As mentioned, the OOK receiver (43) of
Because the OOK receiver (43) compares pulse widths, the frequency of the clock signal generated by the clock generation circuit (55) does not have to be synchronized with the frequency of the external device (20) in order for the OOK receiver (43) to function. Hence, the OOK telemetry link (38) is considered to be “frequency independent” and may be used to communicate with a number of implantable stimulators (10) each having different system clock frequencies.
As shown in
The pulse width counter (141) also outputs a value (B) representing the pulse width for each control bit included in the modulated control data. A comparator (142) may then compare the pulse width of each of the control bits with the pulse width of the start bit. For illustrative purposes only, the start bit is a “0”. Thus, if the pulse width of a particular control bit is greater than the pulse width of the start bit, the comparator (142) outputs a “1”. Likewise, if the pulse width of a particular control bit is less than or equal to the pulse width of the control bit, the comparator (142) outputs a “0”.
As shown in
The preceding description has been presented only to illustrate and describe embodiments of invention. It is not intended to be exhaustive or to limit the invention to any precise form disclosed. Many modifications and variations are possible in light of the above teaching. It is intended that the scope of the invention be defined by the following claims.
The present application is a divisional of U.S. patent application Ser. No. 12/789,716, filed May 28, 2010, which was a continuation of U.S. patent application Ser. No. 11/043,404, filed Jan. 25, 2005 (now U.S. Pat. No. 7,822,480), which was a continuation-in-part of U.S. patent application Ser. No. 10/607,962, filed Jun. 27, 2003 (now U.S. Pat. No. 7,177,698), which claims the benefit of Provisional Application Ser. No. 60/392,475, filed Jun. 28, 2002. Priority is claimed to all of these patent applications under 35 U.S.C. §120 or 119(e), and all are incorporated herein by reference in their entireties.
Number | Name | Date | Kind |
---|---|---|---|
2800616 | Becker | Jul 1957 | A |
3288641 | Rightmire | Nov 1966 | A |
3727616 | Lenzkes | Apr 1973 | A |
4082097 | Mann et al. | Apr 1978 | A |
4134408 | Brownlee et al. | Jan 1979 | A |
4441498 | Nordling | Apr 1984 | A |
4561443 | Hogrefe et al. | Dec 1985 | A |
4612934 | Borkan | Sep 1986 | A |
5193539 | Schulman et al. | Mar 1993 | A |
5193540 | Schulman et al. | Mar 1993 | A |
5312439 | Loeb | May 1994 | A |
5314458 | Najafi et al. | May 1994 | A |
5358514 | Schulman et al. | Oct 1994 | A |
5372605 | Adams et al. | Dec 1994 | A |
5405367 | Schulman et al. | Apr 1995 | A |
5571148 | Loeb et al. | Nov 1996 | A |
5642030 | Seelye | Jun 1997 | A |
5750926 | Schulman et al. | May 1998 | A |
5769877 | Barreras, Sr. | Jun 1998 | A |
5807397 | Barreras | Sep 1998 | A |
5861019 | Sun et al. | Jan 1999 | A |
5951594 | Kerverm | Sep 1999 | A |
6051017 | Loeb et al. | Apr 2000 | A |
6061596 | Richmond et al. | May 2000 | A |
6073050 | Griffith | Jun 2000 | A |
6131581 | Leysieffer et al. | Oct 2000 | A |
6148235 | Kuiper | Nov 2000 | A |
6164284 | Schulman et al. | Dec 2000 | A |
6175764 | Loeb et al. | Jan 2001 | B1 |
6181965 | Loeb et al. | Jan 2001 | B1 |
6185452 | Schulman et al. | Feb 2001 | B1 |
6185455 | Loeb et al. | Feb 2001 | B1 |
6195585 | Karunasiri et al. | Feb 2001 | B1 |
6201993 | Kruse et al. | Mar 2001 | B1 |
6208894 | Schulman et al. | Mar 2001 | B1 |
6212430 | Kung | Apr 2001 | B1 |
6214032 | Loeb et al. | Apr 2001 | B1 |
6240316 | Richmond et al. | May 2001 | B1 |
6259937 | Schulman et al. | Jul 2001 | B1 |
6280873 | Tsukamoto | Aug 2001 | B1 |
6316193 | He et al. | Nov 2001 | B1 |
6366817 | Kung | Apr 2002 | B1 |
6400991 | Kung | Jun 2002 | B1 |
6424867 | Snell et al. | Jul 2002 | B1 |
6434194 | Eisenberg et al. | Aug 2002 | B1 |
6443891 | Grevious | Sep 2002 | B1 |
6458171 | Tsukamoto | Oct 2002 | B1 |
6516227 | Meadows et al. | Feb 2003 | B1 |
6553263 | Meadows et al. | Apr 2003 | B1 |
6567703 | Thompson et al. | May 2003 | B1 |
6582441 | He et al. | Jun 2003 | B1 |
6605382 | Ruth et al. | Aug 2003 | B2 |
6607843 | Ruth, II et al. | Aug 2003 | B2 |
6631296 | Parramon et al. | Oct 2003 | B1 |
6647298 | Abrahamson et al. | Nov 2003 | B2 |
6826430 | Faltys et al. | Nov 2004 | B2 |
6871099 | Whitehurst et al. | Mar 2005 | B1 |
6920359 | Meadows et al. | Jul 2005 | B2 |
6978181 | Snell | Dec 2005 | B1 |
7177698 | Klosterman et al. | Feb 2007 | B2 |
7209792 | Parramon et al. | Apr 2007 | B1 |
7822480 | Park et al. | Oct 2010 | B2 |
7962222 | He et al. | Jun 2011 | B2 |
20010053476 | Ruth et al. | Dec 2001 | A1 |
20020055779 | Andrews | May 2002 | A1 |
20030078634 | Schulman | Apr 2003 | A1 |
20030171787 | Money et al. | Sep 2003 | A1 |
20030171789 | Malek et al. | Sep 2003 | A1 |
20050021108 | Klosterman et al. | Jan 2005 | A1 |
20070032839 | Parramon et al. | Feb 2007 | A1 |
Number | Date | Country |
---|---|---|
9718857 | May 1997 | WO |
0001320 | Jan 2000 | WO |
0160450 | Aug 2001 | WO |
0182398 | Nov 2001 | WO |
0209808 | Feb 2002 | WO |
0222205 | Mar 2002 | WO |
03005465 | Jan 2003 | WO |
Entry |
---|
Cameron, et al., “Micromodular Implants to Provide Electrical Stimulation of Paralyzed Muscles and Limbs,” IEEE Transactions on Biomedical Engineering, vol. 44, No. 9, (Sep. 1997), pp. 781-790. |
Loeb, et al., “North Sea: Transducers and Electrodes—Injectable Microstimulator for Functional Electrical Stimulation,” Med. & Biol. Eng. & Computer, North Sea Special Feature, 29 (Nov. 1991), pp. NS13-NS19. |
Loeb, et al., “BION™ Bionic Neurons for Functional and Therapeutic Electrical Stimulation,” 20th Annual International Conference of IEEE Engineering in Medicine and Biology “Biomedical Engineering Towards the Year 2000 and Beyond,” Oct. 29-Nov. 1, (1998), Hong Kong, 5 pages. |
Number | Date | Country | |
---|---|---|---|
20140107734 A1 | Apr 2014 | US |
Number | Date | Country | |
---|---|---|---|
60392475 | Jun 2002 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 12789716 | May 2010 | US |
Child | 14133233 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 11043404 | Jan 2005 | US |
Child | 12789716 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 10607962 | Jun 2003 | US |
Child | 11043404 | US |