The present invention generally pertains to a pneumatic surgical system. More particularly, but not by way of limitation, the present invention pertains to surgical system pneumatic generation.
Vitreo-retinal procedures may include a variety of surgical procedures performed to restore, preserve, and enhance vision. Vitreo-retinal procedures may be appropriate to treat many serious conditions of the back of the eye. Vitreo-retinal procedures may treat conditions such as age-related macular degeneration (AMD), diabetic retinopathy and diabetic vitreous hemorrhage, macular hole, retinal detachment, epiretinal membrane, CMV retinitis, and many other ophthalmic conditions.
The vitreous is a normally clear, gel-like substance that fills the center of the eye. It may make up approximately ⅔ of the eye's volume, giving it form and shape before birth. Certain problems affecting the back of the eye may require a vitrectomy, or surgical removal of the vitreous.
A vitrectomy may be performed to clear blood and debris from the eye, to remove scar tissue, or to alleviate traction on the retina. Blood, inflammatory cells, debris, and scar tissue may obscure light as it passes through the eye to the retina, resulting in blurred vision. The vitreous may also be removed if it is pulling or tugging the retina from its normal position. Some of the most common eye conditions that require vitrectomy include complications from diabetic retinopathy such as retinal detachment or bleeding, macular hole, retinal detachment, pre-retinal membrane fibrosis, bleeding inside the eye (vitreous hemorrhage), injury or infection, and certain problems related to previous eye surgery.
The retinal surgeon may perform a vitrectomy with a microscope and special lenses designed to provide a clear image of the back of the eye. Several tiny incisions just a few millimeters in length may be made on the sclera. The retinal surgeon may insert microsurgical instruments through the incisions such as a fiber optic light source to illuminate inside the eye, an infusion line to maintain the eye's shape during surgery, and instruments to cut and remove the vitreous.
In a vitrectomy, the surgeon may create three tiny incisions in the eye for three separate instruments. These incisions may be placed in the pars plana of the eye, which is located just behind the iris but in front of the retina. The instruments which pass through these incisions may include a light pipe, an infusion port, and the vitrectomy cutting device. The light pipe is the equivalent of a microscopic high-intensity flashlight for use within the eye. The infusion port may be used to replace fluid in the eye and maintain proper pressure within the eye. The vitrector, or cutting device, may work like a tiny guillotine, with an oscillating microscopic cutter to remove the vitreous gel in a controlled fashion. This may prevent significant traction on the retina during the removal of the vitreous humor.
The surgical machine used to perform a vitrectomy and other surgeries on the posterior of the eye is very complex. Typically, such an ophthalmic surgical machine includes a main console to which the numerous different tools are attached. The main console may provide power to and control the operation of the attached tools.
The attached tools typically include probes, scissors, forceps, illuminators, vitrectors, and infusion lines. Each of these tools is typically attached to the main surgical console. A computer in the main surgical console may monitor and control the operation of these tools. These tools may also get their power from the main surgical console. Some of these tools may be electrically powered while others may be pneumatically powered.
In order to provide pneumatic power to the various tools, the main surgical console may include a pneumatic or air distribution module. This pneumatic module may condition and supply compressed air or gas to power the tools. The pneumatic module may be connected to a cylinder that contains compressed gas. The pneumatic module may provide the proper gas pressure to operate the attached tools properly.
In various embodiments, a pneumatic system valve for a surgical console may be controlled by a controller configured to adjust a valve duty cycle (VDC) (the VDC being used to energize the valve) to reduce a difference between a differential pressure (e.g., an average differential pressure) at the valve's output and a desired differential pressure (e.g., a desired average differential pressure). In some embodiments, average differential pressures may be detected and relayed from a pressure sensor, coupled to one or more ports of the valve, to the controller (e.g., implementing a PID controller (Proportional-Integral-Derivative controller) algorithm). The controller may compare the measured average differential pressure against the desired average differential pressure (e.g., received from the user or determined based on information received from the user). The controller may then determine a modified VDC to reduce a difference between the desired average differential pressure and the measured average differential pressure. In some embodiments, multiple iterations may be performed to reduce the difference between the measured average differential pressure and the desired average differential pressure.
For a more complete understanding of the present invention, reference is made to the following description taken in conjunction with the accompanying drawings in which:
a is diagram of a pneumatic system with a differential pressure sensor, according to an embodiment;
b is diagram of a pneumatic system with separate pressure sensors on each port, according to an embodiment;
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are intended to provide a further explanation of the present invention as claimed.
U.S. Patent Application Publication entitled “Pneumatic System for a Vitrector,” Publication No. 20080149197, Ser. No. 11/614,678, by Denis Turner, Robert Palino, Argelio Olivera, and Mark Hopkins filed Dec. 21, 2006 is hereby incorporated by reference in its entirety as though fully and completely set forth herein.
In some embodiments, pneumatic valve 217 may be a four-way valve. Other valve configurations are also contemplated. The valve 217 may include a solenoid that operates to move the valve 217 to one of the two positions (e.g., see
As seen in
In some embodiments, the valve duty cycle (VDC) may include the amount of time the pneumatic valve 217 is in the first and second positions. In some embodiments, a cut rate of the probe cutter 225 may be controlled by the controller 205 through valve 217. For example, to provide a 2500 cuts per minute probe rate, controller 205 may direct pneumatic valve 217 to provide pressurized air alternately to port A (second channel) and port B (first channel) at a rate of approximately 24 ms per cycle. To obtain a cut rate of 2500 cuts per minute, the two pneumatic channels may cycle open/closed every 24 ms (2500 cuts/min or 1 min/2500 cuts*60 seconds/1 min=0.024 seconds/cut=24 ms/cut), which may open for 12 ms to each channel. In some embodiments, a transition time to actually open and close the channels may use part of the cycle time. For example, pneumatic second channel (i.e., via port A 213 of pneumatic valve 217) may take 4 ms to open (while pneumatic first channel is closing) and 2 ms to close (while pneumatic first channel is opening) for a total transition time per 24 ms cycle of 6 ms. Other transition times are also contemplated. Because of the transition time, the valve may actually be open only 8 ms (12 ms−4 ms) to second channel while closed to first channel and may be closed for 10 ms (12 ms−2 ms) to second channel while open to first channel. This valve timing difference of 8 ms vs. 10 ms in providing pressurized air to second channel and first channel may result in an unbalanced pressure differential in the two channels. In some embodiments, it may be desirable for the open time durations of the two channels to be approximately the same (e.g., in the case of 2500 cuts/minute, actually open for approximately (24 ms−6 ms)/2=9 ms).
If the open/close transition timings were constant for all pneumatic valves 217 then the controller 205 could be preprogrammed with a fixed valve duty cycle to achieve approximately equal actual open time durations for both channels based on a standard pneumatic valve 217. For example, the nominal open time may be set to 13 ms for second channel and 11 ms for first channel. Thus, for this example, excluding transition time, the actual open time of the second channel may be 13 ms−4 ms=9 ms and the actual open time of the first channel may be 11 ms−2 ms=9 ms (similar to second channel). However, because the transition time may vary between various pneumatic valves 217 (e.g., due to manufacturing variances, flow restrictions, temperature, aging, etc. of pneumatic valve 217), a fixed valve duty cycle may not successfully counter the imbalance. For example, a different valve may take 3 ms (instead of 4 ms) to open the second channel (while the pneumatic first channel is closing) and 2 ms to close the second channel (while the pneumatic first channel is opening). If the same valve duty cycle (e.g., 13 ms nominal open time for the second channel and 11 ms nominal open time for the first channel) was applied to this second valve example, the actual open time for the pneumatic second channel of the second valve would be 13 ms−3 ms=10 ms and the actual open time for the first channel would be 11 ms−2 ms=9 ms. Therefore, the valve duty cycle that worked for the previous valve example results in the pneumatic second channel remaining actually open 1 ms or 11% longer than the pneumatic first channel for the second example valve. The difference may result in an uneven power balance between the two pneumatic channels which may result in less desirable performance. Similarly, a fixed valve duty cycle may not successfully counter the imbalance caused by the flow restriction/resistance variations in the two channels from console to console.
In some embodiments, the effects of the valve variation may be dynamically compensated by monitoring the pressure waveform (e.g., the average differential pressures 207 detected over the run time of the valve by pressure sensor 211 (
Initially, a desired differential pressure (between port A and port B) may be determined based on user input (e.g., received through a user interface of the surgical console) or a system default stored in a memory on the surgical console 101 prior to valve operation. During valve operation, the controller 205 may modify the valve duty cycle of the valve 217 based on a detected/calculated actual differential pressure. For example, pressure sensor 211 may detect a pressure difference between port A 213 and port B 215 and send a signal indicative of the pressure difference to controller 205. In some embodiments, the pressure sensor 211 may calculate the average differential pressure 207 based on a detected differential pressure waveform or the pressure sensor 211 may relay the detected differential pressure waveform to the controller 205 and the controller 205 may determine the average differential pressure 207. In some embodiments, the average differential pressure 207 may be sent to the controller 205 as a signal that the controller 205 may interpret to derive the pressure (or, for example, use to derive other values related to pressure). While one pressure sensor 211 is shown in
In some embodiments, the controller 205 may determine time intervals (corresponding to a modified valve duty cycle) to signal valve 217 to be in the first and second positions in order to achieve the desired average differential pressure between port A and port B. By applying an adjusted valve duty cycle to the cycle times for the pneumatic channels, the pneumatic channels may be actuated during the total cycle time to specific actual open times. As noted above, a 50% valve duty cycle may correspond to applying a signal (i.e., to energize the valve into the first position) for approximately the same amount of time as the signal is not applied (i.e., to de-energize the valve into the second position). An adjustment of 1% may result in a 51% valve duty cycle that corresponds to applying a signal to energize (i.e., to the first position) the valve for approximately 51% of the total cycle time (and 49% of the total time no signal is applied (to put the valve into the second position)). The longer 51% valve duty cycle may thus compensate, for example, for a valve that takes longer to move into the first position than it does to move into the second position and or a console that has higher flow restriction/resistance in the channel connecting to the first position of the valve. In some embodiments, the valve duty cycle may also be adjusted for various console characteristics (e.g., to compensate for the different transition times of various valves and flow restriction/resistance variations of various consoles).
In various embodiments, controller 205 may be configured to receive signals from pressure sensor 211 (or pressure sensors 212a,b) via an electronic interface (e.g., electrical conductors such as wires, buses, traces, or the like). Controller 205 may also be configured to send output signals via an electronic interface to pneumatic valve 217. These output signals may allow controller 205 to control the operation of pneumatic valve 217. Controller 205 may include an integrated circuit capable of performing logic functions. In this manner, controller 205 may be in the form of a standard integrated circuit package with power, input, and output pins. In various embodiments, controller 205 may include a valve controller or a targeted device controller. In some embodiments, controller 205 may perform specific control functions targeted to a specific device, such as a valve. In some embodiments, controller 205 may be a microprocessor. In such a case, controller 205 may be programmable so that it can function to control valves as well as other components of the console 101. In some embodiments, controller 205 is not a programmable microprocessor, but instead is a special purpose controller configured to control different valves that perform different functions.
At 401, a user may select a desired cut rate and/or PDC (e.g., based on surgical needs). For example, the user may enter a cut rate of 2500 cuts per minute at a PDC of 50%.
At 403, the desired PDC may be translated into a desired average differential pressure (or other pressure differences/metrics related to the differential pressure between ports A and B). In some embodiments, the desired PDC may be translated into a desired average differential pressure based on a pre-established look-up table (e.g., see
At 405, the pneumatic valve 217 may be controlled by controller 205 to operate tool 103. In some embodiments, the controller 205 may initially control the valve 217 using a default valve duty cycle (e.g., 50%). In some embodiments, controller 205 may receive a desired average differential pressure from an offset translator 203 (e.g., an electronic circuit configured to convert a received electronic signal indicative of the desired PDC 201 into a corresponding desired average differential pressure based on an internal look-up table (e.g., see
At 407, average differential pressures 207 may be relayed from the pressure sensor 211 to the controller 205 (or calculated by the controller 205 using pressure information from pressure sensors 212a,b). For example, the average differential pressures 207 may be relayed by the pressure sensor 211 every 100 milliseconds (or pressure information (e.g., pressure offsets) may be relayed by pressure sensors 212a,b and the average differential pressure 207 may be calculated by the controller 205). Other time intervals are also contemplated (e.g., every 5 seconds). In some embodiments, the pressure sensor 211 may calculate the average differential pressure based on a detected differential pressure waveform or the pressure sensor 211 may relay the detected differential pressure waveform (which may include one or more differential pressures between port A and port B) to the controller 205 and the controller 205 may determine the average differential pressure 207. In some embodiments, pressure sensors 212a,b coupled to ports A and B may relay detected pressure information (e.g., pressure offset, pressure waveform, etc.) to the controller 205 and the controller 205 may determine the average differential pressure for the ports (or may compare the pressure waveforms without actually calculating the average differential pressure).
At 409, the controller 205 may compare the measured average differential pressure 207 (e.g., received from the pressure sensors or calculated using information from the pressure sensors) against the desired average differential pressure (e.g., calculated/determined from information received from the user or a default setting) and determine a modified VDC. The controller 205 may determine a modified VDC to reduce a difference between the desired average differential pressure and the measured average differential pressure. For example, if the pressure at port A is taken as positive pressure and the pressure at port B is taken as negative pressure, then for an ideal valve, the measured average differential pressure may be 0 psi. In this example, if the measured average differential pressure instead is positive (e.g., +2 psi), the measured average differential pressure may indicate that port A is actually staying open longer than port B during a given cycle (resulting in port A being charged to a higher pressure when open than port B charges to when open). If the desired average differential pressure was set at 0 psi, the VDC (which may indicate the percentage of the time the controller 205 signals port A to vent) may be increased by the controller 205 (e.g., from 50% to 51%). In some embodiments, the controller 205 may increase or decrease the VDC according to a default or user provided ratio. In some embodiments, the amount to adjust the VDC in response to the difference between the desired average differential pressure and the measured differential pressure may be experimentally determined for the valve 217. For example, it may be experimentally determined to increase VDC by 1% for every +1.2 psi difference between the measured average differential pressure and the desired average differential pressure (other ratios are also contemplated). This information may be stored in equation or table form accessible to the controller 205. As another example, the controller 205 may increase the VDC by a user provided increment (such as 0.5%) if the average differential pressure is positive and decrease the VDC by the user provided increment if the average differential pressure is negative. In some embodiments, the controller 205 may not adjust the VDC if the measured average differential pressure is within a default or user provided range (e.g., no adjustment if the average differential pressure is within 1 psi of the desired average differential pressure). In some embodiments, the user may enter various inputs for the controller's use (e.g., input into the touchscreen of display 109). For example, the user may enter a ratio of −1% VDC for every +1.2 psi difference between the measured average differential pressure and the desired average differential pressure. In some embodiments, the controller may not actually calculate differential pressures, but may instead compare pressure waveforms from port A and B (e.g., as determined by pressure sensors 212a,b) to each other or to desired waveforms to determine how to adjust the VDC. For example, if the pressure waveform for port A is, on average, 2 psi greater than a desired pressure waveform (e.g., as stored on the system), the VDC may be adjusted without having to actually calculate the differential pressure. Other VDC adjustment techniques are also contemplated.
At 411, the controller 205 may use the modified VDC in energizing the pneumatic valve 217 (e.g., to time the switch between the first/second positions).
At 413, the controller 205 may iterate between comparing the measured average differential pressure 207 against the desired average differential pressure (or related differential pressure variables/metrics) and determining a new modified VDC to minimize a difference between the measured average differential pressure 207 and the desired average differential pressure. For example, the controller 205 may implement a PID controller algorithm (Proportional-Integral-Derivative) to adjust the valve duty cycle upward or downward, receive a new detected average differential pressure (or receive new pressure information to use in calculating the average differential pressure), adjust the valve duty cycle correspondingly upward or downward based on the direction of the new average differential pressure as compared to the previous average differential pressure, receive/calculate a new average differential pressure in response to the modified valve duty cycle, etc. until the difference between the average differential pressure and the desired differential pressure is reduced (e.g., within a user provided range).
In some embodiments, the pneumatic management system may include one or more processors. The processor may include single processing devices or a plurality of processing devices. Such a processing device may be a microprocessor, controller (e.g., controller 205) (which may be a micro-controller), digital signal processor, microcomputer, central processing unit, field programmable gate array, programmable logic device, state machine, logic circuitry, control circuitry, analog circuitry, digital circuitry, and/or any device that manipulates signals (analog and/or digital) based on operational instructions. A memory coupled to and/or embedded in the processors may be a single memory device or a plurality of memory devices. Such a memory device may be a read-only memory, random access memory, volatile memory, non-volatile memory, static memory, dynamic memory, flash memory, cache memory, and/or any device that stores digital information. Note that when the processors implement one or more of its functions via a state machine, analog circuitry, digital circuitry, and/or logic circuitry, the memory storing the corresponding operational instructions may be embedded within, or external to, the circuitry comprising the state machine, analog circuitry, digital circuitry, and/or logic circuitry. The memory may store, and the processor may execute, operational instructions corresponding to at least some of the elements illustrated and described in association with the figures.
As shown in
Various modifications may be made to the presented embodiments by a person of ordinary skill in the art. Other embodiments of the present invention will be apparent to those skilled in the art from consideration of the present specification and practice of the present invention disclosed herein. It is intended that the present specification and examples be considered as exemplary only with a true scope and spirit of the invention being indicated by the following claims and equivalents thereof.
This application claims the benefit of priority of U.S. Provisional Patent Application Ser. No. 61/285,243 titled “Systems and Methods for Dynamic Pneumatic Valve Driver”, filed on Dec. 10, 2009, whose inventors are Shawn X. Gao and Mark A. Hopkins, which is hereby incorporated by reference in its entirety as though fully and completely set forth herein.
Number | Name | Date | Kind |
---|---|---|---|
812162 | Bemis | Feb 1906 | A |
2016746 | Ireland | Oct 1935 | A |
2707389 | Fortier | May 1955 | A |
3084674 | Watson | Apr 1963 | A |
3477665 | Legrand | Nov 1969 | A |
3646727 | Wachsmuth | Mar 1972 | A |
3703139 | Furlong | Nov 1972 | A |
3815604 | O'Malley et al. | Jun 1974 | A |
3854382 | Walters et al. | Dec 1974 | A |
3867934 | Ollivier | Feb 1975 | A |
4011869 | Seiler, Jr. | Mar 1977 | A |
4077567 | Ginn et al. | Mar 1978 | A |
4086804 | Ruby | May 1978 | A |
4164167 | Imai et al. | Aug 1979 | A |
4168707 | Douvas et al. | Sep 1979 | A |
4253480 | Kessel et al. | Mar 1981 | A |
4323064 | Hoenig et al. | Apr 1982 | A |
4331130 | Lewicky | May 1982 | A |
4335867 | Bihlmaier | Jun 1982 | A |
4344144 | Damico et al. | Aug 1982 | A |
4368734 | Banko | Jan 1983 | A |
4373549 | Nalepa et al. | Feb 1983 | A |
4476532 | Akiyama et al. | Oct 1984 | A |
4590935 | Ranalli | May 1986 | A |
4622503 | Sundblom et al. | Nov 1986 | A |
4650460 | Roizenblatt | Mar 1987 | A |
4650462 | DeSatnick et al. | Mar 1987 | A |
4678459 | Onik et al. | Jul 1987 | A |
4679583 | Lucas et al. | Jul 1987 | A |
4696298 | Higgins et al. | Sep 1987 | A |
4706687 | Rogers et al. | Nov 1987 | A |
4757814 | Wang et al. | Jul 1988 | A |
4770654 | Rogers et al. | Sep 1988 | A |
4790816 | Sundblom et al. | Dec 1988 | A |
4810242 | Sundblom et al. | Mar 1989 | A |
4840111 | Garnjost | Jun 1989 | A |
4933843 | Scheller et al. | Jun 1990 | A |
4985027 | Dressel | Jan 1991 | A |
5019035 | Missirlian et al. | May 1991 | A |
5020315 | Leachman, Jr. et al. | Jun 1991 | A |
5020825 | Lizell | Jun 1991 | A |
5024654 | Tyler | Jun 1991 | A |
5047008 | de Juan, Jr. et al. | Sep 1991 | A |
5092178 | Vanderlaan | Mar 1992 | A |
5094260 | Stuart et al. | Mar 1992 | A |
5106364 | Hayafuji et al. | Apr 1992 | A |
5138564 | de Jong et al. | Aug 1992 | A |
5154207 | Bolt | Oct 1992 | A |
5176628 | Charles et al. | Jan 1993 | A |
5217465 | Steppe | Jun 1993 | A |
5239861 | Fujita et al. | Aug 1993 | A |
5314295 | Lukkari et al. | May 1994 | A |
5380280 | Peterson | Jan 1995 | A |
5403276 | Schechter et al. | Apr 1995 | A |
5417246 | Perkins et al. | May 1995 | A |
5437241 | Rosenberg et al. | Aug 1995 | A |
5445773 | Arai | Aug 1995 | A |
5457625 | Lim et al. | Oct 1995 | A |
5549139 | Perkins et al. | Aug 1996 | A |
5550685 | Drouin | Aug 1996 | A |
5571248 | Seetharaman et al. | Nov 1996 | A |
5580347 | Reimels | Dec 1996 | A |
5587536 | Rasmussen | Dec 1996 | A |
5630827 | Vijfvinkel | May 1997 | A |
5674194 | Jung et al. | Oct 1997 | A |
5791142 | Layne et al. | Aug 1998 | A |
5808396 | Boukhny | Sep 1998 | A |
5810765 | Oda | Sep 1998 | A |
5829335 | Ewald et al. | Nov 1998 | A |
5846257 | Hood | Dec 1998 | A |
5857485 | Perkins et al. | Jan 1999 | A |
5959390 | Boukhny | Sep 1999 | A |
5979494 | Perkins et al. | Nov 1999 | A |
5989262 | Josephberg | Nov 1999 | A |
5993409 | Maaskamp | Nov 1999 | A |
6155233 | Wade et al. | Dec 2000 | A |
6162187 | Buzzard et al. | Dec 2000 | A |
6425883 | Urich et al. | Jul 2002 | B1 |
6450966 | Hanna | Sep 2002 | B1 |
6485436 | Truckai et al. | Nov 2002 | B1 |
6514268 | Finlay et al. | Feb 2003 | B2 |
6575264 | Spadafora | Jun 2003 | B2 |
6575990 | Wang et al. | Jun 2003 | B1 |
6678584 | Junk et al. | Jan 2004 | B2 |
6730106 | Kanda et al. | May 2004 | B2 |
6773445 | Finlay et al. | Aug 2004 | B2 |
6779541 | Inayama et al. | Aug 2004 | B2 |
6848323 | Krouth et al. | Feb 2005 | B2 |
6851453 | Lipscomb et al. | Feb 2005 | B2 |
6892745 | Benson | May 2005 | B2 |
6954683 | Junk et al. | Oct 2005 | B2 |
6999853 | Junk et al. | Feb 2006 | B2 |
7244240 | Nazarifar et al. | Jul 2007 | B2 |
7263877 | Schaefer et al. | Sep 2007 | B2 |
7283321 | Sun et al. | Oct 2007 | B1 |
7335217 | Wang et al. | Feb 2008 | B2 |
7337041 | Junk et al. | Feb 2008 | B2 |
7352287 | Rupert | Apr 2008 | B2 |
7470277 | Finlay et al. | Dec 2008 | B2 |
7600405 | Maurer, Jr. et al. | Oct 2009 | B2 |
7628054 | Hajishah et al. | Dec 2009 | B2 |
7640119 | Khashayar | Dec 2009 | B2 |
7708734 | Khashayar | May 2010 | B2 |
7775052 | Cornwell et al. | Aug 2010 | B2 |
8038692 | Valencia et al. | Oct 2011 | B2 |
8157145 | Shelton, IV et al. | Apr 2012 | B2 |
8187293 | Kirchhevel | May 2012 | B2 |
8202277 | Ryan | Jun 2012 | B2 |
8215108 | Hahn et al. | Jul 2012 | B2 |
8230877 | Roberge et al. | Jul 2012 | B2 |
8308737 | Ryan | Nov 2012 | B2 |
20020117214 | Tucker et al. | Aug 2002 | A1 |
20030042182 | Moscaritolo | Mar 2003 | A1 |
20030195538 | Wang et al. | Oct 2003 | A1 |
20030208305 | Junk et al. | Nov 2003 | A1 |
20040154466 | Gethmann et al. | Aug 2004 | A1 |
20040186484 | Ryan | Sep 2004 | A1 |
20050033309 | Ryan | Feb 2005 | A1 |
20050245909 | McCary et al. | Nov 2005 | A1 |
20060129062 | Nicoson et al. | Jun 2006 | A1 |
20060271082 | Kirchhevel et al. | Nov 2006 | A1 |
20070093793 | Maurer, Jr. et al. | Apr 2007 | A1 |
20070185512 | Kirchhevel | Aug 2007 | A1 |
20070219647 | Heertjes et al. | Sep 2007 | A1 |
20070270735 | Williams et al. | Nov 2007 | A1 |
20070270746 | King | Nov 2007 | A1 |
20070282262 | Williams et al. | Dec 2007 | A1 |
20080082077 | Williams | Apr 2008 | A1 |
20080103433 | Nazarifar et al. | May 2008 | A1 |
20080108980 | Turner et al. | May 2008 | A1 |
20080110236 | Hajishah et al. | May 2008 | A1 |
20080142093 | Turner et al. | Jun 2008 | A1 |
20080146988 | Olivera et al. | Jun 2008 | A1 |
20080149197 | Turner et al. | Jun 2008 | A1 |
20080168985 | Turner et al. | Jul 2008 | A1 |
20080172077 | Valencia et al. | Jul 2008 | A1 |
20080300580 | Shelton, IV et al. | Dec 2008 | A1 |
20090082715 | Charles et al. | Mar 2009 | A1 |
20090124962 | Hopkins et al. | May 2009 | A1 |
20090203480 | Petzold et al. | Aug 2009 | A1 |
20090259242 | Gerg et al. | Oct 2009 | A1 |
20090287233 | Huculak | Nov 2009 | A1 |
20090305214 | Pybus et al. | Dec 2009 | A1 |
20100145374 | Perkins et al. | Jun 2010 | A1 |
20100305596 | Peterson et al. | Dec 2010 | A1 |
20100312169 | Auld et al. | Dec 2010 | A1 |
20110005387 | Ehre et al. | Jan 2011 | A1 |
20110054508 | Zhou et al. | Mar 2011 | A1 |
20110295293 | Agahi | Dec 2011 | A1 |
20110299943 | Woolever | Dec 2011 | A1 |
20120010602 | Ryan | Jan 2012 | A1 |
20120055329 | Heer | Mar 2012 | A1 |
20120157906 | Underwood | Jun 2012 | A1 |
20120157907 | Underwood | Jun 2012 | A1 |
20120157908 | Underwood | Jun 2012 | A1 |
20120157909 | Underwood | Jun 2012 | A1 |
20120158006 | MdDonell | Jun 2012 | A1 |
20120158029 | Underwood | Jun 2012 | A1 |
20120158030 | Underwood | Jun 2012 | A1 |
20120221033 | Auld | Aug 2012 | A1 |
Number | Date | Country |
---|---|---|
3708989 | Oct 1988 | DE |
3925405 | Feb 1991 | DE |
4232586 | Mar 1994 | DE |
19821420 | Oct 1999 | DE |
10247869 | May 2004 | DE |
202005009670 | Sep 2005 | DE |
10247869 | Feb 2007 | DE |
102006030034 | Jan 2008 | DE |
0469641 | Jun 1989 | EP |
0626628 | Nov 1994 | EP |
0673475 | Jun 1996 | EP |
0626628 | Dec 1997 | EP |
0874163 | Oct 1998 | EP |
0884667 | Dec 1998 | EP |
0874163 | Mar 1999 | EP |
1074271 | Feb 2001 | EP |
1074271 | Feb 2002 | EP |
1172586 | Mar 2004 | EP |
1074271 | Oct 2004 | EP |
1660244 | Dec 2006 | EP |
2032878 | Dec 2009 | EP |
792397 | Mar 1958 | GB |
1189493 | Jun 1970 | GB |
1213723 | Nov 1970 | GB |
1 323 788 | Jul 1973 | GB |
1417299 | Dec 1975 | GB |
2016746 | Sep 1979 | GB |
2 140 871 | Dec 1984 | GB |
2203195 | Oct 1988 | GB |
2389423 | Dec 2003 | GB |
07259801 | Oct 1995 | JP |
09225698 | Sep 1997 | JP |
9311091 | Dec 1997 | JP |
2010057642 | Mar 2010 | JP |
9202866 | Feb 1992 | WO |
9318445 | Sep 1993 | WO |
WO 9531141 | Nov 1995 | WO |
9825556 | Jun 1998 | WO |
WO 0078371 | Dec 2000 | WO |
WO 0130281 | May 2001 | WO |
WO 0164120 | Sep 2001 | WO |
WO 2008000599 | Jan 2008 | WO |
2008029066 | Mar 2008 | WO |
WO 2008054944 | May 2008 | WO |
WO 2008079526 | Jul 2008 | WO |
WO 2008079526 | Aug 2008 | WO |
WO 2008105950 | Sep 2008 | WO |
WO 2008140537 | Nov 2008 | WO |
WO 2008147429 | Dec 2008 | WO |
WO 2008147429 | Mar 2009 | WO |
WO 2008105950 | Sep 2009 | WO |
WO 2010066302 | Jun 2010 | WO |
WO 2011025658 | Mar 2011 | WO |
2011071613 | Jun 2011 | WO |
WO 2011071655 | Jun 2011 | WO |
2011138102 | Nov 2011 | WO |
WO 2011149621 | Dec 2011 | WO |
Entry |
---|
International Searching Authority, International Search Report, PCT/US2010/056305, Mar. 2, 2011, 3 pages. |
International Searching Authority, Written Opinion of the International Searching Authority, PCT/US2010/056305, Mar. 2, 2011, 7 pages. |
International Searching Authority, International Search Report, PCT/US2010/045136, Nov. 18, 2010, 4 pages. |
International Searching Authority, Written Opinion of the International Searching Authority, PCT/US2010/045136, Nov. 18, 2010, 6 pages. |
Nguyen, Tuan Van, Non-Final Office Action, U.S. Appl. No. 12/788,609, Jan. 18, 2012, 32 pages. |
International Searching Authority, International Search Report, PCT/US2011/034720, Jul. 28, 2011, 2 pages. |
International Searching Authority, Written Opinion of the International Searching Authority, PCT/US2011/034720, Jul. 20, 2011, 8 pages. |
Nguyen, Tuan Van, Non-Final Office Action, U.S. Appl. No. 12/788,609, Jul. 12, 2012, 24 pages. |
Kabei, Shimemura, et al., A portable pneumatic driving unit for a left ventricular assist device, Int. J. Artif. Organs, 1988, 186-90, 11(3). |
Nachlas, Marvin, et al., A simple portable pneumatic pump for external cardiac massage, The American Journal of Cardiology, 1962, 107-109, 10(1). |
Waldeck, J.L., The development of a portable pressure source for the static and dynamic calibration of pressure transducers, The Journal of Wind Engineering and Industrial Aerodynamics, 1987, 213-230, 26(2). |
Ellis, George, et al., Microcomputer-Controlled Precision Pressure Generator, IEEE Transactions on Instrumentation and Measurement, 1977, 214-217, 26(3). |
Whalen, R.L., et al., An electromagnetic pneumatic blood pump driver, American Society of Artificial Internal Organs, 1988, 721-725, 34(3). |
Turkentine, R.B., et al., Pressure-operated shutter for thin-film monitor, Journal of Physics E: Scientific Instruments, 1979, 12(1). |
Rogers, Richard C., An inexpensive picoliter-vol. pressure ejection system, Brain Research Bulletin, 1985, 669-671, 15(6). |
Johnson, Kenneth S., et al., A submersible flow analysis System, Analytical Chimica Acta, 1986, 245-257, 179. |
Tabassum, Alim Abid, Solar refrigeration: evaluation of technical options and design of a solar-generator-adsorber for a novel adsorption refrigerator, Tabassum thesis abstract, Cranfield University, 1989. |
Buchanan, P.R., et al., Recovery of ventilation distributions by gas wash-out of a mechanical pump, Clinical Physics and Physiological Measurement, 1986, 7(3). |
Agahi, Daryush, “Feedback of On/Off Pneumatic Actuators,” U.S. Appl. No. 12/788,609, filed May 27, 2010, 24 pgs. |
Zhou, Jason, et al., “Pneumatic Pressure Output Control by Drive Valve Duty Cycle Calibration,” U.S. Appl. No. 12/854,281, filed Aug. 11, 2010, 38 pgs. |
International Searching Authority, International Search Report, PCT/US2012/049695, Oct. 24, 2012, 2 pages. |
International Searching Authority, Written Opinion of the International Searching Authority, PCT/2012/049695, Oct. 24, 2012, 4 pages. |
Number | Date | Country | |
---|---|---|---|
20110144675 A1 | Jun 2011 | US |
Number | Date | Country | |
---|---|---|---|
61285243 | Dec 2009 | US |