The present invention generally relates to aneurysm treatment devices and more particularly, to delivery systems for embolic implants.
Numerous intravascular implant devices are known in the field. Many are deployed mechanically, via systems that combine one or more catheters and wires for delivery. Examples of implants that can be delivered mechanically include embolic elements, stents, grafts, drug delivery implants, flow diverters, filters, stimulation leads, sensing leads, or other implantable structures delivered through a microcatheter. Some obstetric and gastrointestinal implants may also be implanted via similar systems that combine one or more catheters and wires. Devices that may be released or deployed by mechanical means vary greatly in design but can employ a similar delivery catheter and wire system. Many such catheter-based delivery systems include a wire for retention of the implant in the catheter until the time for release of the device. These systems are then actuated by retracting or pulling the wire relative to the catheter. Such a wire is referred to herein as a “pull wire”.
To pull the pull wire proximally to deploy the implant, a physician can use one of many known deployment apparatuses. Such mechanical deployment apparatuses are typically separate from the delivery system and have moving parts for gripping the pull wire and for moving the pull wire proximally. Deployment methods and apparatuses that do not require auxiliary components and/or complex moving parts can simplify treatment procedures and reduce cost. There is therefore a need for simplified mechanical implant deployment apparatuses.
Disclosed herein are various exemplary systems, devices, and methods of the present invention that can address the above needs. Examples can generally include an embolic implantation system that includes an embolic implant, a delivery system, and an introducer sheath that are collectively designed so that the combination of the introducer sheath and the delivery system can be used as a deployment apparatus for the embolic implant. The delivery system can have a pull wire, a delivery tube, and an interference feature attached to the pull wire and positioned at a proximal end of the delivery tube. The introducer sheath can be moved proximally over the delivery tube until it engages the interference feature. To deploy the implant, the introducer sheath can be pressed against the interference feature, causing the interference feature to move proximally in relation to the delivery tube, thereby proximally pulling the pull wire to which the interference feature is attached and deploying the implant.
An example implantation system can include a delivery tube, an embolic coil, an introducer sheath, an interference feature, and an elongated member. The embolic coil can be detachably attached to a distal end of the delivery tube. The interference feature can be positioned at a proximal end of the delivery tube and movable in relation to the delivery tube. The elongated member can be positioned within a lumen of the delivery tube and attached to the interference feature. The introducer sheath can have a lumen sized to slidably receive the delivery tube and the embolic coil, the introducer sheath can be translatable over the delivery tube from the distal end of the delivery tube to the proximal end of the delivery tube, and the introducer sheath can be sized to engage the interference feature. The interference feature can be movable in relation to the delivery tube in response to a force applied by the introducer sheath against the interference feature. The elongated member can be movable in relation to the delivery tube in response to a proximal movement of the interference feature.
The interference feature can be detachable from the delivery tube. The elongated member can be movable to exit the proximal end of the delivery tube in response to a proximal movement of the detached interference feature.
The delivery tube can have a soft section near the distal end of the delivery tube. The length of the embolic coil and the soft section as measured from a distal end of the un-implanted embolic coil to a proximal end of the soft section can be shorter than the end-to-end length of the introducer sheath so that the introducer sheath is sized to fully encompass the un-implanted embolic coil and the soft section. The introducer sheath can be longer than the length of the embolic coil and soft section by about 5 cm.
The system can include a microcatheter, and the delivery tube can have an end-to-end length that is longer than the sum of the end-to-end length of the introducer sheath and an end-to-end length of the microcatheter.
The end-to-end length of the introducer sheath can be between about 46 cm to about 105 cm.
The introducer sheath can be movable from a packaged configuration in which the introducer sheath is positioned to completely encompass the soft section and the embolic coil to a deployment configuration in which the introducer sheath is engaged with the interference feature.
The embolic coil can be detached from the delivery tube by moving the elongated member proximally in relation to the delivery tube.
The interference feature can have a substantially circular surface positioned to engage the proximal end of the introducer sheath.
A distal end of the introducer sheath can be sized to engage a microcatheter to create an enclosed interface through which the embolic coil and at least a portion of the delivery tube can pass.
An example implantation assembly can include a delivery tube, an embolic implant, a pull wire, an engagement bump, and a tubular sheath. The embolic implant can be attached to a distal end of the delivery tube. The pull wire can be disposed within a lumen of the delivery tube and movable to detach the embolic implant from the delivery tube. The engagement bump can be disposed on a proximal end of the pull wire and positioned near a proximal end of the delivery tube. The tubular sheath can be conveyable over the embolic implant and the delivery tube from a distal end of the embolic implant to the proximal end of the delivery tube, and the tubular sheath can be sized to engage the engagement bump. The engagement bump and the pull wire can be movable in relation to the delivery tube in response to a force applied by the tubular sheath to the engagement bump.
The delivery tube can have a soft section extending proximally from the distal end of the delivery tube, and the tubular sheath can measure end-to-end about 5 cm longer than a length measured from a distal end of the embolic implant to a proximal end of the soft section when the embolic implant is attached to the delivery tube and extended in an un-implanted configuration.
The assembly can include a microcatheter, and the delivery tube can have an end-to-end length that is greater than the sum of the length of the introducer sheath and the microcatheter.
The tubular sheath can be movable from a packaged configuration in which the tubular sheath is positioned to completely encompass the soft section and the embolic coil to a deployment configuration in which the tubular sheath is engaged with the engagement bump.
The engagement bump can be detachable from the delivery tube in response to the force applied by the tubular sheath to the engagement bump. The pull wire can be movable to detach the embolic implant from the delivery tube in response to the force applied by the tubular sheath to the engagement bump.
An example method for treating an aneurysm can include the steps of providing an implantation system including an embolic implant, an introducer sheath, a delivery tube, an interference feature, and a pull wire; affixing the pull wire to the interference feature; positioning the pull wire within a lumen of the delivery tube; attaching the interference feature to a proximal end of the delivery tube; attaching the embolic implant at a distal end of the delivery tube; positioning the introducer sheath to encompass the embolic implant and a first portion of the delivery tube; sliding the introducer sheath proximally over the delivery tube; pulling the introducer sheath proximally to apply a force from the introducer sheath to the interference feature; and moving the interference feature and the pull wire proximally in relation to the delivery tube in response to the force.
The first portion of the delivery tube over which the introducer sheath is positioned in the example method can have a soft section. The method can include sizing the introducer sheath to have a length that is greater than the length of the embolic implant and the soft section by about 5 cm. The method can include sizing the introducer sheath to have a length of between about 46 cm to about 105 cm, the length measurable from a distal end to a proximal end of the introducer sheath.
The method can include detaching the embolic implant from the delivery tube in response to moving the interference feature and the pull wire proximally in relation to the delivery tube. The method can include detaching the interference feature from the delivery tube. The interference feature can be detached in response to moving the interference feature and the pull wire proximally in relation to the delivery tube.
The method can include providing a microcatheter; positioning the introducer sheath to engage with the microcatheter while maintaining the embolic implant and the first portion of the delivery tube within the inducer sheath; and translating the embolic implant and the delivery tube distally to position the embolic implant and the first portion of the delivery tube within the microcatheter.
The above and further aspects of this invention are further discussed with reference to the following description in conjunction with the accompanying drawings, in which like numerals indicate like structural elements and features in various figures. The drawings are not necessarily to scale, emphasis instead being placed upon illustrating principles of the invention. The figures depict one or more implementations of the inventive devices, by way of example only, not by way of limitation.
Examples presented herein utilize an introducer sheath to facilitate mechanical deployment of an implant. Examples of implants that can be delivered mechanically include embolic elements, stents, grafts, drug delivery implants, flow diverters, filters, stimulation leads, sensing leads, or other implantable structures deliverable through a microcatheter. Some implants are currently packaged with an introducer sheath that is removed from the device and discarded near the beginning of an implantation procedure. For example, in existing systems, embolic coils and other embolic implants can be used to occlude vessels in a variety of medical applications. In many instances, prior to implantation and during handling of an embolic implant outside of a patient, the embolic implant is contained in an introducer sheath. In present treatment practices, once the embolic implant is transferred to a microcatheter, the introducer sheath would be removed from the delivery system and discarded before the embolic implant reaches a treatment site. In examples presented herein, according to the present invention, rather than being discarded, the introducer sheath can be slid proximally and can facilitate deployment of the embolic implant, i.e. detachment of the embolic implant from the delivery system. In order to use the introducer sheath to facilitate deployment, the delivery system can have an interference feature positioned at a proximal end of a delivery tube and attached to a pull wire, and the combination of the introducer sheath, delivery tube, pull wire, and interference feature can be configured such that the introducer sheath can engage with the interference feature and move the interference feature proximally in relation to the delivery tube, thereby pulling the pull wire proximally and deploying the embolic implant. The delivery tube, microcatheter, and introducer sheath can each have a respective length sized such that the introducer sheath can be long enough to cover the embolic implant and sensitive portions of the delivery system, and the delivery tube can be long enough to extend through the entire length of the microcatheter and the entire length of the introducer sheath.
The introducer sheath 180 can have a lumen therethrough that is sized to slidably receive the delivery tube 110 and the embolic implant 140. The introducer sheath 180 can be sized such that it can be translated proximally from the position illustrated in
The interference feature 120 can be movable in relation to the delivery tube 110. For example, the interference feature 120 can be detachably attached to the proximal end 112 of the delivery tube 110, and the system 100 can include a disconnection feature 122 that can be unhooked, torn, broken, twisted, or otherwise manipulated to disconnect the interference feature 120 from the delivery tube 110.
The delivery tube 110 can have a soft section 116 positioned near a distal end 114 of the delivery tube 110 that has a greater flexibility than the remainder (proximal portion) 118 of the delivery tube 110. The embolic implant 140 can be detachably attached to a distal end 114 of the delivery tube 114. The soft section 116 can be designed to allow greater control and stability of the distal end 114 of the delivery tube 110 during implantation and deployment of the embolic implant 140. The soft section 116 can have laser cut notches or groves, and/or the soft section 116 can be made of a more flexible material compared to the remainder 118 of the delivery tube 110.
The introducer sheath 180 can serve the purpose of protecting (packaging) the embolic implant 140 and the soft section 116 of the delivery tube 110 as the system 100 is being handled prior to, and at the beginning of a patient treatment procedure. For this purpose, it is therefore desirable for the introducer sheath 180 to be long enough to completely encompass the embolic implant 140 and the soft section 116 prior to the treatment procedure. The combined length of the embolic implant 140 and the soft section 116 can be measured from a distal end 144 of the embolic implant 140 to a proximal end 117 of the soft section 116. The introducer sheath 180 can have a length measurable from a distal end 184 to a proximal end 182 of the introducer sheath that can be sized a few centimeters longer than the combined length of the embolic implant 140 and the soft section 116 to ensure that the embolic implant 140 and soft section 116 remain protected in case portions of the system 100 shift during handling prior to the treatment procedure. The introducer sheath 180 can have a length that is about 5 cm longer than the combined length of the embolic implant 140 and the soft section 116. For example, the embolic implant 140 can have a length of between about 1 cm and about 60 cm, the soft section 116 can have a length of about 40 cm, and the introducer sheath can have a length that is about 5 cm longer than the sum of the embolic implant 140 length and the soft section 116 length, i.e. between about 46 cm and about 105 cm.
The introducer sheath 180 can be sized to engage the interference feature 120. As illustrated, the introducer sheath 180 can be tubular and can have a circular proximal end 182, and the interference feature 120 can protrude radially beyond a circumference of the delivery tube 110. The interference feature 120 can be circular, having a circumference larger than a circumference of the proximal end 182 of the introducer sheath 180. The interference feature 120 can provide a flat surface against which the proximal end 182 of the introducer sheath 180 can press. Additionally, or alternatively, the interference feature can have a non-flat surface that can have a slope or a groove for receiving the introducer sheath 180. The interference feature 120 can be a bump positioned near the distal end of the delivery tube that extends beyond the circumference of the delivery tube and extends so that the introducer sheath 180, when slid proximally over the delivery tube 110, must engage the interference feature 120 before sliding completely over and off the proximal end 112 of the delivery tube 110.
While
An aneurysm can be treated with an implantation system such as any of the implantation systems disclosed herein in relation to the present invention by executing some or all the following steps, not necessarily in order. An implantation system 100 having an embolic implant 140, an introducer sheath 180, a delivery tube 110, an interference feature 120, and a pull wire 130 can be provided. The pull wire 130 can be affixed to the interference feature 120. The pull wire 130 can be positioned within a lumen of the delivery tube 110. The interference feature 120 can be attached to a proximal end 112 of the delivery tube 110. The embolic implant 140 can be attached at a distal end 114 of the delivery tube 110. The introducer sheath 180 can be positioned to encompass the embolic implant 140 and a first portion of the delivery tube 110. The first portion of the delivery tube 110 can comprise a soft section 116. The introducer sheath can be sized to have an end-to-end length that is longer by about 5 cm than a length measurable from a distal end 144 of the embolic implant 140 to a proximal end 117 of the soft section 116. The introducer sheath 180 can be sized so that the end-to-end length is between about 46 cm and about 105 cm. A microcatheter 200 can be provided. The introducer sheath 180 can be positioned to engage with the microcatheter 200 while maintaining the embolic implant 140 and the first portion of the delivery tube 110 within the introducer sheath 180. The embolic implant 140 and the delivery tube 110 can be translated distally to position the embolic implant 140 and the first portion of the delivery tube 110 within the microcatheter 200. The introducer sheath 180 can be slid proximally over the delivery tube 110. The introducer sheath 180 can be pulled proximally to apply a force from the introducer sheath 180 to the interference feature 120. The interference feature 120 and the pull wire 130 can be moved proximally in relation to the delivery tube 110 in response to the force. The interference feature 120 can be detached from the delivery tube 110. The embolic implant 140 can be detached from the delivery tube 110 in response to moving the interference feature 120 and the pull wire 130 proximally in relation to the delivery tube 110.
The descriptions contained herein are examples of embodiments of the invention and are not intended in any way to limit the scope of the invention. As described herein, the invention contemplates many variations and modifications of the implantation system and associated methods, including alternative geometries of system components, alternative materials, additional or alternative method steps, etc. These modifications would be apparent to those having ordinary skill in the art to which this invention relates and are intended to be within the scope of the claims which follow.
Number | Name | Date | Kind |
---|---|---|---|
3429408 | Maker et al. | Feb 1969 | A |
5108407 | Geremia et al. | Apr 1992 | A |
5122136 | Guglielmi et al. | Jun 1992 | A |
5250071 | Palermo | Oct 1993 | A |
5263964 | Purdy | Nov 1993 | A |
5334210 | Gianturco | Aug 1994 | A |
5350397 | Palermo et al. | Sep 1994 | A |
5382259 | Phelps et al. | Jan 1995 | A |
5484409 | Atkinson et al. | Jan 1996 | A |
5569221 | Houser et al. | Oct 1996 | A |
5899935 | Ding | May 1999 | A |
5925059 | Palermo et al. | Jul 1999 | A |
6113622 | Hieshima | Sep 2000 | A |
6203547 | Nguyen et al. | Mar 2001 | B1 |
6391037 | Greenhalgh | May 2002 | B1 |
6454780 | Wallace | Sep 2002 | B1 |
6506204 | Mazzocchi | Jan 2003 | B2 |
6561988 | Turturro et al. | May 2003 | B1 |
7367987 | Balgobin et al. | May 2008 | B2 |
7371251 | Mitelberg et al. | May 2008 | B2 |
7371252 | Balgobin et al. | May 2008 | B2 |
7377932 | Mitelberg et al. | May 2008 | B2 |
7708754 | Balgobin et al. | May 2010 | B2 |
7708755 | Davis, III et al. | May 2010 | B2 |
7799052 | Balgobin et al. | Sep 2010 | B2 |
7811305 | Balgobin et al. | Oct 2010 | B2 |
7819891 | Balgobin et al. | Oct 2010 | B2 |
7819892 | Balgobin et al. | Oct 2010 | B2 |
7901444 | Slazas | Mar 2011 | B2 |
7985238 | Balgobin et al. | Jul 2011 | B2 |
8062325 | Mitelberg et al. | Nov 2011 | B2 |
8333796 | Tompkins et al. | Dec 2012 | B2 |
9155540 | Lorenzo | Oct 2015 | B2 |
9232992 | Heidner et al. | Jan 2016 | B2 |
9314326 | Wallace et al. | Apr 2016 | B2 |
9532792 | Galdonik et al. | Jan 2017 | B2 |
9532873 | Kelley | Jan 2017 | B2 |
9533344 | Monetti et al. | Jan 2017 | B2 |
9539011 | Chen et al. | Jan 2017 | B2 |
9539022 | Bowman | Jan 2017 | B2 |
9539122 | Burke et al. | Jan 2017 | B2 |
9539382 | Nelson | Jan 2017 | B2 |
9549830 | Bruszewski et al. | Jan 2017 | B2 |
9554805 | Tompkins et al. | Jan 2017 | B2 |
9561125 | Bowman et al. | Feb 2017 | B2 |
9572982 | Burnes et al. | Feb 2017 | B2 |
9579484 | Barnell | Feb 2017 | B2 |
9585642 | Dinsmoor et al. | Mar 2017 | B2 |
9615832 | Bose et al. | Apr 2017 | B2 |
9615951 | Bennett et al. | Apr 2017 | B2 |
9622753 | Cox | Apr 2017 | B2 |
9636115 | Henry et al. | May 2017 | B2 |
9636439 | Chu et al. | May 2017 | B2 |
9642675 | Werneth et al. | May 2017 | B2 |
9655633 | Leynov et al. | May 2017 | B2 |
9655645 | Staunton | May 2017 | B2 |
9655989 | Cruise et al. | May 2017 | B2 |
9662120 | Lagodzki et al. | May 2017 | B2 |
9662129 | Galdonik et al. | May 2017 | B2 |
9662238 | Dwork et al. | May 2017 | B2 |
9662425 | Lilja et al. | May 2017 | B2 |
9668898 | Wong | Jun 2017 | B2 |
9675477 | Thompson | Jun 2017 | B2 |
9675782 | Connolly | Jun 2017 | B2 |
9676022 | Ensign | Jun 2017 | B2 |
9692557 | Murphy | Jun 2017 | B2 |
9693852 | Lam et al. | Jul 2017 | B2 |
9700262 | Janik et al. | Jul 2017 | B2 |
9700399 | Acosta-Acevedo | Jul 2017 | B2 |
9717421 | Griswold et al. | Aug 2017 | B2 |
9717500 | Tieu et al. | Aug 2017 | B2 |
9717502 | Teoh et al. | Aug 2017 | B2 |
9724103 | Cruise et al. | Aug 2017 | B2 |
9724526 | Strother et al. | Aug 2017 | B2 |
9750565 | Bloom et al. | Sep 2017 | B2 |
9757260 | Greenan | Sep 2017 | B2 |
9764111 | Gulachenski | Sep 2017 | B2 |
9770251 | Bowman | Sep 2017 | B2 |
9770577 | Li | Sep 2017 | B2 |
9775621 | Tompkins et al. | Oct 2017 | B2 |
9775706 | Paterson | Oct 2017 | B2 |
9775732 | Khenansho | Oct 2017 | B2 |
9788800 | Mayoras, Jr. | Oct 2017 | B2 |
9795391 | Saatchi et al. | Oct 2017 | B2 |
9801980 | Karino et al. | Oct 2017 | B2 |
9808599 | Bowman | Nov 2017 | B2 |
9833252 | Sepetka | Dec 2017 | B2 |
9833604 | Lam | Dec 2017 | B2 |
9833625 | Waldhauser et al. | Dec 2017 | B2 |
9918718 | Lorenzo | Mar 2018 | B2 |
10285710 | Lorenzo et al. | May 2019 | B2 |
10517604 | Bowman et al. | Dec 2019 | B2 |
10806402 | Cadieu et al. | Oct 2020 | B2 |
10806461 | Lorenzo | Oct 2020 | B2 |
20010049519 | Holman et al. | Dec 2001 | A1 |
20020072705 | Vrba et al. | Jun 2002 | A1 |
20020165569 | Ramzipoor et al. | Nov 2002 | A1 |
20040034363 | Wilson et al. | Feb 2004 | A1 |
20040059367 | Davis | Mar 2004 | A1 |
20040087964 | Diaz | May 2004 | A1 |
20060025801 | Lulo et al. | Feb 2006 | A1 |
20060064151 | Guterman et al. | Mar 2006 | A1 |
20060116711 | Elliott et al. | Jun 2006 | A1 |
20060116714 | Sepetka et al. | Jun 2006 | A1 |
20060135986 | Wallace et al. | Jun 2006 | A1 |
20060206139 | Tekulve | Sep 2006 | A1 |
20060247677 | Cheng et al. | Nov 2006 | A1 |
20060276824 | Mitelberg et al. | Dec 2006 | A1 |
20060276825 | Mitelberg et al. | Dec 2006 | A1 |
20060276826 | Mitelberg et al. | Dec 2006 | A1 |
20060276827 | Mitelberg et al. | Dec 2006 | A1 |
20060276830 | Balgobin et al. | Dec 2006 | A1 |
20060276833 | Balgobin et al. | Dec 2006 | A1 |
20070010850 | Balgobin | Jan 2007 | A1 |
20070055302 | Henry et al. | Mar 2007 | A1 |
20070083132 | Sharrow | Apr 2007 | A1 |
20070233168 | Davis et al. | Oct 2007 | A1 |
20070270903 | Davis, III et al. | Nov 2007 | A1 |
20080027561 | Mitelberg et al. | Jan 2008 | A1 |
20080045997 | Balgobin et al. | Feb 2008 | A1 |
20080097462 | Mitelberg et al. | Apr 2008 | A1 |
20080281350 | Sepetka et al. | Nov 2008 | A1 |
20080300616 | Que et al. | Dec 2008 | A1 |
20080306503 | Que et al. | Dec 2008 | A1 |
20090062726 | Ford et al. | Mar 2009 | A1 |
20090312748 | Johnson et al. | Dec 2009 | A1 |
20100114017 | Lenker et al. | May 2010 | A1 |
20100324649 | Mattsson et al. | Dec 2010 | A1 |
20110202085 | Loganathan et al. | Aug 2011 | A1 |
20110295303 | Freudenthal | Dec 2011 | A1 |
20120035707 | Mitelberg et al. | Feb 2012 | A1 |
20120041472 | Tan et al. | Feb 2012 | A1 |
20120283768 | Cox et al. | Nov 2012 | A1 |
20130066413 | Jin | Mar 2013 | A1 |
20140058435 | Jones et al. | Feb 2014 | A1 |
20140135812 | Divino et al. | May 2014 | A1 |
20140200607 | Sepetka et al. | Jul 2014 | A1 |
20140277084 | Mirigian et al. | Sep 2014 | A1 |
20140277085 | Mirigian et al. | Sep 2014 | A1 |
20140277092 | Teoh et al. | Sep 2014 | A1 |
20140277093 | Guo | Sep 2014 | A1 |
20150005808 | Chouinard et al. | Jan 2015 | A1 |
20150182227 | Le | Jul 2015 | A1 |
20150230802 | Lagodzki et al. | Aug 2015 | A1 |
20150335333 | Jones et al. | Nov 2015 | A1 |
20160008003 | Kleshinski et al. | Jan 2016 | A1 |
20160022275 | Garza | Jan 2016 | A1 |
20160157869 | Elgård et al. | Jun 2016 | A1 |
20160228125 | Pederson, Jr. | Aug 2016 | A1 |
20160310304 | Mialhe | Oct 2016 | A1 |
20160346508 | Williams et al. | Dec 2016 | A1 |
20170007264 | Cruise et al. | Jan 2017 | A1 |
20170007265 | Guo et al. | Jan 2017 | A1 |
20170020670 | Murray et al. | Jan 2017 | A1 |
20170020700 | Bienvenu | Jan 2017 | A1 |
20170027640 | Kunis et al. | Feb 2017 | A1 |
20170027692 | Bonhoeffer | Feb 2017 | A1 |
20170027725 | Argentine | Feb 2017 | A1 |
20170035436 | Morita | Feb 2017 | A1 |
20170035567 | Duffy | Feb 2017 | A1 |
20170042548 | Lam | Feb 2017 | A1 |
20170049596 | Schabert | Feb 2017 | A1 |
20170071737 | Kelley | Mar 2017 | A1 |
20170072452 | Monetti et al. | Mar 2017 | A1 |
20170079671 | Morero | Mar 2017 | A1 |
20170079680 | Bowman | Mar 2017 | A1 |
20170079766 | Wang | Mar 2017 | A1 |
20170079767 | Leon-Yip | Mar 2017 | A1 |
20170079812 | Lam et al. | Mar 2017 | A1 |
20170079817 | Sepetka | Mar 2017 | A1 |
20170079819 | Pung et al. | Mar 2017 | A1 |
20170079820 | Lam et al. | Mar 2017 | A1 |
20170086851 | Wallace | Mar 2017 | A1 |
20170086996 | Peterson et al. | Mar 2017 | A1 |
20170095258 | Tassoni et al. | Apr 2017 | A1 |
20170095259 | Tompkins et al. | Apr 2017 | A1 |
20170100126 | Bowman et al. | Apr 2017 | A1 |
20170100141 | Morero et al. | Apr 2017 | A1 |
20170100143 | Granfield | Apr 2017 | A1 |
20170100183 | Iaizzo | Apr 2017 | A1 |
20170113023 | Steingisser et al. | Apr 2017 | A1 |
20170147765 | Mehta | May 2017 | A1 |
20170151032 | Loisel | Jun 2017 | A1 |
20170165062 | Rothstein | Jun 2017 | A1 |
20170165065 | Rothstein | Jun 2017 | A1 |
20170165454 | Tuohy | Jun 2017 | A1 |
20170172581 | Bose et al. | Jun 2017 | A1 |
20170172766 | Vong et al. | Jun 2017 | A1 |
20170172772 | Khenansho | Jun 2017 | A1 |
20170189033 | Sepetka et al. | Jul 2017 | A1 |
20170189035 | Porter | Jul 2017 | A1 |
20170215902 | Leynov et al. | Aug 2017 | A1 |
20170216484 | Cruise et al. | Aug 2017 | A1 |
20170224350 | Shimizu et al. | Aug 2017 | A1 |
20170224355 | Bowman et al. | Aug 2017 | A1 |
20170224467 | Piccagli et al. | Aug 2017 | A1 |
20170224511 | Dwork et al. | Aug 2017 | A1 |
20170224953 | Tran et al. | Aug 2017 | A1 |
20170231749 | Perkins et al. | Aug 2017 | A1 |
20170245864 | Franano et al. | Aug 2017 | A1 |
20170245885 | Lenker | Aug 2017 | A1 |
20170252064 | Staunton | Sep 2017 | A1 |
20170258476 | Hayakawa et al. | Sep 2017 | A1 |
20170265983 | Lam et al. | Sep 2017 | A1 |
20170281192 | Tieu et al. | Oct 2017 | A1 |
20170281331 | Perkins et al. | Oct 2017 | A1 |
20170281344 | Costello | Oct 2017 | A1 |
20170281909 | Northrop et al. | Oct 2017 | A1 |
20170281912 | Melder | Oct 2017 | A1 |
20170290593 | Cruise et al. | Oct 2017 | A1 |
20170290654 | Sethna | Oct 2017 | A1 |
20170296324 | Argentine | Oct 2017 | A1 |
20170296325 | Marrocco et al. | Oct 2017 | A1 |
20170303939 | Greenhalgh | Oct 2017 | A1 |
20170303942 | Greenhalgh et al. | Oct 2017 | A1 |
20170303947 | Greenhalgh | Oct 2017 | A1 |
20170303948 | Wallace et al. | Oct 2017 | A1 |
20170304041 | Argentine | Oct 2017 | A1 |
20170304097 | Corwin et al. | Oct 2017 | A1 |
20170304595 | Nagasrinivasa | Oct 2017 | A1 |
20170312109 | Le | Nov 2017 | A1 |
20170312484 | Shipley et al. | Nov 2017 | A1 |
20170316561 | Helm et al. | Nov 2017 | A1 |
20170319826 | Bowman | Nov 2017 | A1 |
20170333228 | Orth et al. | Nov 2017 | A1 |
20170333236 | Greenan | Nov 2017 | A1 |
20170333678 | Bowman | Nov 2017 | A1 |
20170340383 | Bloom et al. | Nov 2017 | A1 |
20170348014 | Wallace | Dec 2017 | A1 |
20170348514 | Guyon et al. | Dec 2017 | A1 |
20180028779 | von Oepen et al. | Feb 2018 | A1 |
20180036508 | Ozasa et al. | Feb 2018 | A1 |
20180228493 | Aguilar et al. | Aug 2018 | A1 |
20180250150 | Majercak | Sep 2018 | A1 |
20180280667 | Keren | Oct 2018 | A1 |
20180325706 | Hebert | Nov 2018 | A1 |
20190159784 | Sananes et al. | May 2019 | A1 |
20190192162 | Lorenzo | Jun 2019 | A1 |
20190255290 | Snyder et al. | Aug 2019 | A1 |
20190314033 | Mirigian et al. | Oct 2019 | A1 |
20190328398 | Lorenzo | Oct 2019 | A1 |
20200138448 | Dasnurkar et al. | May 2020 | A1 |
20200187951 | Blumenstyk | Jun 2020 | A1 |
20210001082 | Lorenzo et al. | Jan 2021 | A1 |
Number | Date | Country |
---|---|---|
1985244 | Oct 2008 | EP |
2498691 | Sep 2012 | EP |
3092956 | Nov 2016 | EP |
3501427 | Jun 2019 | EP |
2006-334408 | Dec 2006 | JP |
2012-523943 | Oct 2012 | JP |
2013-78584 | May 2013 | JP |
WO 2009132045 | Oct 2009 | WO |
WO 2012158152 | Nov 2012 | WO |
WO 2017066386 | Apr 2017 | WO |
WO 2018022186 | Feb 2018 | WO |
Entry |
---|
Extended European Search Report issued in corresponding European Patent Application No. 19 21 5318 dated Apr. 8, 2020. |
Extended European Search Report issued in corresponding European Patent Application No. 20 21 2970 dated May 28, 2021. |
Extended European Search Report issued in European Patent Application No. 21 15 6857 dated Jun. 22, 2021. |
Number | Date | Country | |
---|---|---|---|
20200187951 A1 | Jun 2020 | US |