Patent Application
20230356116
The present disclosure relates to separating particles. In particular, the present disclosure relates to separating particles in fluids.
Particles dispersed in fluid may be problematic in certain systems, such as engine fuel systems, bulk fuel systems, hydraulic systems, or other systems for handling or storing fluid. For example, particles of water (or water droplets) in fuel may be problematic in engine fuel systems of internal combustion engines. Water in fuel may damage fuel injectors due to corrosion or vaporization during combustion. Damage to injectors may cause various problems in operation of the engine, such as failing to be able to comply with jurisdictional emission standards. Fuel injector damage may require repair or maintenance. Reduced operating time may be particularly costly for commercial or industrial vehicles. In general, the presence of gaseous, liquid, or solid particles dispersed in fluid may cause issues in various fluid systems, such as bulk fuel systems, hydraulic systems, etc. Traditional fluid filters capture particles in a media structure. The media structure may become plugged over time requiring maintenance or filter replacement.
The techniques of this disclosure generally relate to focusing certain particles in fluid in various fluid systems and separating those certain particles from the fluid or from particles of other sizes. In general, fluid systems may include particle separation elements, such as hydrodynamic separation elements, to focus particles in a particular size range. The particle separation element may include an inlet and an outlet having at least two flow branches. Particles of the particular size range may be focused into one of the two flow branches. In some embodiments, particles exceeding a threshold size range are focused into one of the two flow branches. Any remaining particles may flow through the at least two flow branches. In some embodiments, the particle separation element may be used to supplement or replace a fluid filter.
In one aspect, the present disclosure relates to a hydrodynamic separator. A system includes a hydrodynamic separation element having one or more hydrodynamic separators each defining a curved microfluidic channel in fluid communication. Each microfluidic channel defines an inlet configured to receive a fluid and particles dispersed in the fluid, wherein the particles have a different composition than the fluid, and an outlet including a first flow branch and a second flow branch. At a predetermined flow rate, each microfluidic channel is configured to direct any particles exceeding a corresponding threshold size into the second flow branch and any remaining particles into both the first flow branch and the second flow branch. The system also includes a particle sensor positioned along the one or more hydrodynamic separators configured to provide signal data representing a signal corresponding to the fluid and the particles in the fluid. The system further includes a controller operably coupled to the particle sensor to receive the signal data and operably couplable to a fluid pump in fluid communication with the hydrodynamic separation element. The controller is configured to: control the fluid pump to direct fluid through the hydrodynamic separation element, determine whether a threshold level of particles is present in at least one microfluidic channel based on the signal data from the particle sensor, and control a flow rate through the hydrodynamic separation element, in response to determining that the threshold level of particles is present in the at least one microfluidic channel, to direct fluid at the predetermined flow rate through the hydrodynamic separation element to focus any particles exceeding the corresponding threshold size to the second flow branch of the at least one microfluidic channel.
In another aspect, the present disclosure relates to a particle diverter. A system includes a particle separation element. The particle separation element includes one or more microfluidic channels in parallel fluid communication. Each microfluidic channel defines an inlet configured to receive a fluid and particles dispersed in the fluid, wherein the particles have a different composition than the fluid, and an outlet including a first flow branch and a second flow branch. The system also includes a flow routing element positioned along at least one flow branch of at least one outlet. The system further includes a particle sensor positioned along the one or more microfluidic channels configured to provide signal data representing a signal corresponding to the fluid and the particles dispersed in the fluid. The system includes a controller operably coupled to the at least one flow routing element and operably coupled to the particle sensor to receive the signal data. The controller is configured to: control the flow routing element to direct fluid flow to the first flow branch of the at least one outlet of at least one microfluidic channel, determine whether a threshold level of particles is present in at least one microfluidic channel based on the signal data from the particle sensor, and control the flow routing element, in response to determining that the threshold level of particles is present in the at least one microfluidic channel, to direct fluid flow to the second flow branch of the at least one microfluidic channel.
In another aspect, the present disclosure relates to a particle sorter. A system includes a hydrodynamic separation element having a plurality of hydrodynamic separators in series fluid communication including at least a first hydrodynamic separator and a second hydrodynamic separator each defining a curved microfluidic separation channel to separate particles of different size ranges. Each microfluidic separation channel defines an inlet configured to receive a fluid containing particles and an outlet including a first flow branch and a second flow branch. At a particular flow rate, each microfluidic separation channel is configured to direct any particles exceeding a corresponding threshold size into the second flow branch and any remaining particles into both the first flow branch and the second flow branch, wherein the first flow branch of the first hydrodynamic separator is in fluid communication with the inlet of the second hydrodynamic separator. The system also includes a microfluidic sensing element in fluid communication with the hydrodynamic separation element. The microfluidic sensing element includes a plurality of microfluidic sensing channels each in fluid communication with a different flow branch of the hydrodynamic separation element. The plurality of microfluidic sensing channels includes at least: a first microfluidic sensing channel in fluid communication with the second flow branch of the first hydrodynamic separator to receive any particles exceeding a first threshold size and a second microfluidic sensing channel in fluid communication with the second flow branch of the second hydrodynamic separator to receive any particles exceeding a second threshold size, wherein the first threshold size is greater than the second threshold size.
In yet another aspect, the present disclosure relates to orifice patterns. A system includes a plurality of microfluidic sensing channels each configured to receive a flow of a fluid and particles dispersed in the fluid. The particles have a different composition than the fluid. The system also includes a light source configured to direct a light beam in a frequency band along a path through the plurality of microfluidic sensing channels. The frequency band is selected to have a different absorbance by the particles than by the fluid. The system further includes an aperture element defining a plurality of light apertures having a different set of light apertures aligned to each microfluidic sensing channel. Each set of light apertures defines a unique spacing pattern along the corresponding microfluidic sensing channel. The system also includes a light detector positioned to receive the light beam in a sensing area after passing through the plurality of light apertures of the aperture element and through the plurality of microfluidic sensing channels. The light detector is configured to provide a signal representing an amount of light in the frequency band that remains after passing through the plurality of microfluidic sensing channels. Further, the system includes a controller operably coupled to the light detector and configured to: determine signal data based on the signal from the light detector, determine whether a particle has passed through the sensing area based on the signal data, and determine the unique spacing pattern associated with the particle passed through the sensing area based on the signal data.
In still another aspect, the present disclosure relates to water drop detection. A system includes the system according to the present disclosure, wherein the particles include a second fluid different than the fluid.
In a further aspect, the present disclosure relates to an engine fuel system. A system includes a fuel line configured to deliver fuel to a fuel injector system. The system also includes a hydrodynamic separation element having one or more hydrodynamic separators each defining a curved microfluidic channel to separate particles in the fuel. Each microfluidic channel defines an inlet in fluid communication with the fuel line to receive fuel and an outlet including a first flow branch in fluid communication with the fuel line to provide fuel to the fuel injector system and a second flow branch to receive particles in a particular size range.
In another aspect, the present disclosure relates to a bulk fuel system. A system includes a fuel line configured to deliver fuel from a bulk fuel storage tank to a vehicle fuel tank. The system also includes a hydrodynamic separation element having one or more hydrodynamic separators each defining a curved microfluidic channel to separate particles in the fuel. Each microfluidic channel defines an inlet in fluid communication with the fuel line to receive fuel and an outlet including a first flow branch in fluid communication with the fuel line to provide fuel to the vehicle fuel tank and a second flow branch to receive particles in a particular size range.
In still another aspect, the present disclosure relates to a hydraulic particle filter. A system includes a hydraulic fluid line configured to deliver hydraulic fluid from a hydraulic pump to a hydraulic component. The system also includes a hydrodynamic separation element having one or more hydrodynamic separators each defining a curved microfluidic channel to separate particles in the hydraulic fluid. Each microfluidic channel defines an inlet in fluid communication with the hydraulic fluid line to receive hydraulic fluid from the hydraulic pump and an outlet including a first flow branch in fluid communication with the hydraulic fluid line to provide hydraulic fluid to the hydraulic component and a second flow branch to receive particles in a particular size range.
In yet another aspect, the present disclosure relates to enhancing hydraulic deaeration. A system includes a hydraulic fluid return line configured to deliver hydraulic fluid from a hydraulic component to a hydraulic pump. The system also includes a hydrodynamic separation element having one or more hydrodynamic separators each defining a curved microfluidic channel to separate particles in the hydraulic fluid. Each microfluidic channel defines an inlet in fluid communication with the hydraulic fluid line to receive hydraulic fluid from the hydraulic pump and an outlet including a first flow branch in fluid communication with the hydraulic fluid line to provide hydraulic fluid to the hydraulic pump and a second flow branch to receive particles in a particular size range.
Various embodiments of the disclosure are illustrated in the drawings, which are summarized as follows:
In the following detailed description, reference is made to several specific embodiments. It is to be understood that other embodiments are contemplated and may be made without departing from the scope or spirit of the present disclosure. The following detailed description, therefore, is not to be taken in a limiting sense.
This disclosure provides techniques to focus certain particles in fluid in various fluid systems and to separate those certain particles from the fluid or from particles of other sizes. In general, fluid systems may include particle separation elements, such as hydrodynamic separation elements, to focus particles in a particular size range. The particle separation element may include an inlet and an outlet having at least two flow branches. Particles of the particular size range may be focused into one of the two flow branches. In some embodiments, particles exceeding a threshold size range are focused into one of the two flow branches. Any remaining particles may flow through the at least two flow branches. In some embodiments, the particle separation element may be used to supplement or replace a fluid filter.
Particle separation elements, which may include hydrodynamic separation elements, may be used as filter replacements or supplements. In particular, particle separation elements may be used to concentrate particles above a critical size into a portion of a fluid flow. This portion of the fluid flow may be removed from the system, thus removing most particles exceeding a threshold size. In some cases, this may replace some or all of the functionality of a filter. The performance of particle separation elements may not change over time and may not need regular replacement. In some embodiments, a filter may be used downstream of the particle separation element to remove particles below the threshold size. Further, in some embodiments, the particles focused by the particle separation element are filtered. This may be done at a lower face velocity than in a system without a particle separation element, and thus lead to a lower filter pressure drop and longer filter life.
Particle separation elements, which may include hydrodynamic separation elements, may also be used to sort particles of different sizes. In some applications, a threshold size may be determined. The particle separation element may be designed to concentrate particles above the threshold size into a concentrated fluid portion of a fluid flow. The concentrated portion of the fluid flow may be removed from the system. This technique may be used to concentrate particles for particle counting. This technique may also be used to separate different types of particles or to concentrate certain materials for collection.
A microfluidic particle sensor, or microfluidic sensing element, may be used for detecting individual contaminants in a fluid, such as a liquid stream. A separator or segmentation stage may be positioned upstream from the particle sensor. The segmentation stage, or particle separation element, may separate particles into different fluid streamlines based on particle size. This could be accomplished, for example, with Dean Flow Separation. Once particles are in streamlines based on their particle size, the streamlines are sent into different sensing channels of a microfluidic sensing element. The sensing channels are associated with particle sensors that count the number of particles. By knowing the number of particles in each sensing channel an approximate particle size distribution may be determined. The sensor may be an optical sensor, capacitance sensor, magnetic sensor, or other sensor. Alternatively, the particle sensor may contain only a microfluidic channel and a sensor. Use of the microfluidic channel may increase sensitivity for individual contaminants relative to other techniques, such as Mie scattering. Signal processing may also be used to identify contaminant type.
Further, particle separation elements, which may include hydrodynamic separation elements, may be used for selective particle waste removal. In some cases, only particles above a certain size may be targeted for removal from a system. Uses for selective particle waste removal may include, but are not limited, to: removal or concentration of fats in milk (fats are typically 0.1 to 15 micrometer agglomerates), removal or concentration of orange juice pulp, removal of contaminates in semi-conducting processing fluids, and removal of ink agglomerates in industrial ink processing. In one example related to wafer polishing slurries, particle separation elements may be designed to remove particles above a threshold size, which may be agglomerates or impurities, while letting particles below the threshold size through.
As used herein, the term “particle” refers to a discrete amount of material, which may be dispersed in a different fluid. Non-limiting examples of material that may be formed particles include dirt, metal, air bubbles, and water droplets. In one particular example, water droplets may be dispersed in a hydrocarbon fluid, such as gasoline or diesel fuel, to form an emulsion. In another example, air bubbles may be dispersed in a hydraulic fluid.
As used herein, the term “downstream” refers to a direction along a fluid flow. The term “upstream” refers to the opposite of downstream, or a direction opposite to the fluid flow.
As used herein, the term “microfluidic channel” refers to a channel having at least one dimension less than 1 millimeter (1000 micrometers). A microfluidic channel may have a channel width less than 1000 micrometers, a channel height (or depth) less than 1000 micrometers, or both. In some embodiments, for higher flow applications, at least one dimension of the microfluidic channel may be greater than 1 millimeter. In some embodiments, at least one dimension of the microfluidic channel is greater than or equal to 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10 millimeters or less than or equal to 10, 9, 8, 7, 6, 5, 4, 3, or 2 millimeters. In general, the channel may have any suitable length to provide a suitable pressure drop balanced with suitable particle focusing.
Microfluidic channels may be described by a cross-sectional area, width×height. In some embodiments, the cross-sectional area of the microfluidic channel may be less than 10, 9, 8, 7, 6, 5, 4, 3, or 2 millimeters squared.
Microfluidic channels may also be described by a hydraulic diameter. For a microfluidic channel having a rectangular cross-section, for example, the hydraulic diameter may be calculated as:
where DH is the hydraulic diameter. Other cross-sectional shapes may be calculated according to techniques known to one of ordinary skill in the art having the benefit of this disclosure. In some embodiments, the hydraulic diameter of the microfluidic channel may be less than 5, 4, 3, 2, or 1 millimeter. In at least one embodiment, the hydraulic diameter of the microfluidic channel of the microfluidic channel may be less than 1 millimeter.
As used herein, the term “hydrodynamic separator” refers to a curved fluid channel including, at least, an inlet to receive a fluid flow and an outlet including at least two branches to divide the fluid flow. The fluid channel may be a microfluidic channel. The inlet may receive a fluid that may contain particles of various sizes. At a particular flow rate, the hydrodynamic separator is configured to focus any particles exceeding a threshold size into one the branches. Any remaining particles are not focused in the fluid flow. The remaining particles may be divided among all branches, for example, based on a volume fractions, or outlet flow rate ratios, associated with each branch. Hydrodynamic separators may be designed based on at least one or more of the following parameters: a Dean number, a Reynolds number, a hydraulic diameter, a radius of curvature, a target flow rate, target pressure drop, critical particle size, fluid viscosity, operating temperature (which may affect fluid viscosity), a ratio of outlet flow rates, or any combination of these. Hydrodynamic separators may also be described as Dean Flow Separators.
In general, hydrodynamic separators include curving microfluidic channels designed to focus particles exceeding a threshold size to the inside wall of the curve. The cross-sectional area of the microfluidic channel limits the maximum particle size that may enter the microfluidic channel. The device defines a geometry (such as width, height, radius of curvature, and channel length) designed to focus particles in a known fluid at a specific flow rate or flowrate range. The focused particles close to the inner wall may then be removed from the system by removing a portion of the fluid close to the inner wall. In other embodiments, depending on the device geometry and operating conditions, the particles and the waste stream may alternatively be focused close to the outer wall. The design of the device may be dependent on application flow rate, fluid properties (such as viscosity and density), and threshold particle size. The hydrodynamic separator may act as a filter or as a pre-filter in a system.
Curving microfluidic channels can be used to focus particles of a pre-determined size under appropriate flow conditions. In a curving channel or pipe under laminar flow conditions, the inertia of the fluid creates a pressure gradient across the channel. To alleviate the pressure gradient, two spiraling flows known as Dean Flows (sometimes referred to as secondary flows) may form. The Dean Flow may exhibit drag on any particles in the fluid. In larger channels, the particles may be swept along the channel in a spiraling motion. When channels become smaller, such as in microfluidic channels, the Dean Flow can be balanced with two additional forces such that particles can become trapped and focused on the inner wall of the curving channel. These forces may be described the shear-induced lift force, which causes a lift force towards the wall, and the wall-induced lift force that pushes the particle away from the wall due to bounding of fluid flow as the particle approaches the wall. Particles may be focused into a specific streamline within the curving channel. Focusing particles in this manner may be referred to as Hydrodynamic Separation or Dean Flow Separation.
As used herein, a “flow routing element” refers to a component configured to allow for selective routing of a fluid flow leaving a fluid channel. Non-limiting examples of components of a flow routing element include a valve or a solenoid. In one example, a flow routing element may include one or more valves configured to divert flow to one or more branches in any suitable manner.
The Dean number describes fluid behavior in a curved pipe and accounts for inertial forces, centripetal forces, and viscous forces acting on the fluid. In various embodiments, the system is configured to have a Dean Number between 5 and 25. The Dean number is defined as:
where Re is the Reynolds number and Rc is the radius of curvature of the fluid channel
The Reynolds number describes the ratio of inertial forces to viscous forces, and is defined as:
where p is the fluid density, U is the average fluid velocity, and μ is the dynamic viscosity of the fluid.
Reference will now be made to the drawings, which depict one or more aspects described in this disclosure. However, it will be understood that other aspects not depicted in the drawings fall within the scope of this disclosure. Like numbers used in the figures refer to like components, steps, and the like. However, it will be understood that the use of a reference character to refer to an element in a given figure is not intended to limit the element in another figure labeled with the same reference character. In addition, the use of different reference characters to refer to elements in different figures is not intended to indicate that the differently referenced elements cannot be the same or similar.
The particle separation element 102 may be fluidly coupled between the fluid source 104 and a fluid destination, such as optional fluid destinations 106, 108. The particle separation element 102 may be positioned downstream of the fluid source 104. The particle separation element 102 may be positioned upstream of the fluid destinations 106, 108. The fluid destination 106 may be a component of the fluid system 100 that stores, uses, or consumes, the fluid, such as fuel being consumed by an engine. The fluid destination 108 may be a component of the fluid system 100 that uses the fluid and returns the fluid to the fluid source 104, such as a hydraulic fluid used in a hydraulic piston. The particle separation element 102 may remove particles in a particular size range from the fluid before providing the fluid to one of the fluid destinations 106, 108.
The particle separation element 102 may include any suitable components usable to remove particles or sort particles in the fluid. In some embodiments, the particle separation element 102 includes a hydrodynamic separation element. In general, the particle separation element 102, which may include the hydrodynamic separation element, may not become loaded with particles and may not change performance over time or require regular replacement.
The hydrodynamic separation element may include one or more hydrodynamic separators. In some embodiments, the hydrodynamic separators are arranged in parallel. The channel length and arrangement of the hydrodynamic separators may be designed to provide target pressure drops.
In some embodiments, the particle separation element 102 includes a flow routing element. The flow routing element may be disposed in the outlet of the particle separation element 102. Flow routing element may include one or more valves or solenoids to divert the flow of fluid.
In general, the particle separation element 102 includes an outlet having at least two different branches. The fluid flow may be divided between the different branches. In some embodiments, using the hydrodynamic separation element, all particles in particular size range may be focused into one of the branches. Each branch may be associated with particles in different size ranges (see
Each branch may be directed to, or in fluid communication with, a different fluid destination. In some embodiments, one branch may be directed to the fluid destination 106 and another branch may be directed to the fluid destination 108.
A fluid pump 114 may be used to control a flow rate of fluid through the particle separation element 102. The fluid pump 114 may be positioned in any suitable location relative to the particle separation element 102 to facilitate control of the flow rate, such as upstream, downstream, or integrated with the particle separation element. In the illustrated embodiment the fluid pump 114 is positioned upstream from the particle separation element 102.
A particle sensor 112 may be used to detect any particles in the fluid flow. The particle sensor 112 may be positioned in any suitable location relative to the particle separation element 102 to facilitate detection of certain particles, such as upstream, downstream, or integrated with the particle separation element. In some embodiments, particle sensor 112 may be positioned between the inlet and the outlet of the particle separation element 102. The particle sensor 112 may use any suitable type of mechanism to detect particles in the fluid. For example, the particle sensor 112 may include or be a light-based particle sensor 200 (
A microfluidic sensing element 116 may be used to sense particles of different sizes from one or more of the branches of the particle separation element 102. The microfluidic sensing element 116 is shown positioned downstream of the particle separation element 102. In some embodiments, the microfluidic sensing element 116 may be described as being part of particle separation element 102. The microfluidic sensing element 116 may include one or more microfluidic sensing channels. In some embodiments, the microfluidic sensing channels are arranged in parallel. The channel length and arrangement of the microfluidic sensing channels may be designed to provide target pressure drops and particle focusing.
Each microfluidic channel may be fluidly coupled to one of the branches of the particle separation element 102. The microfluidic sensing element 116 may also include one or more particle sensors 112 to detect different sizes of particles that have been sorted by the particle separation element 102. The microfluidic sensing element 116 may also be used to determine whether the particle separation element 102 has successfully removed some or all particles in a particular size range. The microfluidic sensing element 116 may also include a flow routing element. The flow routing element may be used to facilitate removal of particles in a particular size range.
A fluid subsystem 120 may be defined which may include one or more of: the particle separation element 102, the fluid pump 114, the microfluidic sensing element 116, and a controller 110. The controller 110 may be used to facilitate various functionality of the fluid subsystem 120 described herein.
Various configurations of the fluid system 100 are contemplated. Non-limiting examples of further configurations and various components of the fluid system 100 are shown and described herein in more detail.
In one example, which may be described as a kidney loop filter (not shown), the fluid pump 114 may be used to provide a fluid flow from the fluid source 104, or source reservoir, through the particle separation element 102, which may include a hydrodynamic separator element, that returns a main flow to the fluid source 104 through a filter. Industrial systems with liquid fluids can use kidney loop filtration systems to remove particles. The particle separation element 102 may be used between the fluid pump 114 and filter. The particle separation element 102 may provide a main outlet flow to the fluid source 104 and return a secondary outlet flow containing certain particle to the filter, which may concentrate particles and minimize the volume of fluid that needs to be filtered as well as lower the face velocity, which may decrease the filter pressure drop.
One or more of the components, such as the controllers, sensors, detectors, or systems, described herein may include a processor, such as a central processing unit (CPU), computer, logic array, or other device capable of directing data coming into or out of the component. The processor may include one or more computing devices having memory, processing, and communication hardware. The processor may include circuitry used to couple various components of the controller together or with other components operably coupled to the controller. The functions of the processor may be performed by hardware and/or as computer instructions on a non-transient computer readable storage medium.
The processor may include any one or more of a microprocessor, a microcontroller, a digital signal processor (DSP), an application specific integrated circuit (ASIC), a field-programmable gate array (FPGA), and/or equivalent discrete or integrated logic circuitry. In some examples, the processor may include multiple components, such as any combination of one or more microprocessors, one or more controllers, one or more DSPs, one or more ASICs, and/or one or more FPGAs, as well as other discrete or integrated logic circuitry. The functions attributed to the processor herein may be embodied as software, firmware, hardware, or any combination thereof
In one or more embodiments, the functionality of the processor may be implemented using one or more computer programs using a computing apparatus, which may include one or more processors and/or memory. Program code and/or logic described herein may be applied to input data/information to perform functionality described herein and generate desired output data/information. The output data/information may be applied as an input to one or more other devices and/or methods as described herein or as would be applied in a known fashion. In view of the above, it will be readily apparent that the controller functionality as described herein may be implemented in any manner known to one skilled in the art.
As illustrated, the fluid pump 114, such as a fuel pump or lift pump, may be used to provide a fluid flow, such as fuel, from the fluid source 104, such as a fuel tank, through the particle separation element 102 through the main fuel line 122. The particle separation element 102 may provide a main outlet flow along the main fuel line 122 using a first flow branch 123 to the fluid destination 106, such as a fuel injector system, which may include a high-pressure common rail, and return a secondary outlet flow containing certain particles to the fluid source 104 along a second flow branch 124. Non-limiting examples of particles include dirt and water droplets.
The particle separation element 102 may be positioned upstream or downstream of the fluid pump 114. In the illustrated embodiment, the particle separation element 102 is positioned downstream of the fluid pump 114. A filter 126 may be positioned downstream of the particle separation element 102 along the main fuel line 122. The filter 126, or fuel filter, may be configured to filter particles from gasoline or diesel fuel. The fluid system 120 may also include a fuel return line 128 from the fluid destination 106 to the fluid source 104. In other embodiments (not shown), the filter 126 may be positioned along, or another filter 126 may also be positioned along, the second flow branch 124, which may filter particles at a lower flowrate and pressure drop.
The particle separation element 102 may be configured to remove particles exceeding, or greater than, a particular threshold size in diameter from the main fuel line 122 while the fluid pump 114 provides fuel at a particular flow rate for engine operation and provide such particles to the second flow branch 124. Non-limiting examples of particular threshold sizes include 1, 2, 5, 10, 15, or 20 micrometers.
The outlet of the particle separation element 102 may be described as having two outlet flows: a “clean” outlet flow along the first flow branch 123 to main fuel line 122 and a “dirty” outlet flow along the second flow branch 124. The clean outlet flow may be predominately free of particles above the threshold size. The clean outlet flow may be sent to the filter 126 and ultimately the fluid destination 106, shown as a high-pressure common rail of a fuel injector system. The dirty outlet flow may contain most of the particles above the critical size. The dirty stream may be sent back to the fluid source 104, shown as a fuel tank. In other embodiments, the dirty outlet flow may be combined with the fuel return line coming from the high-pressure common rail system. In other words, the second flow branch 124 may be fluidly coupled to the fuel return line 128 before returning to the fluid source 104. The particle separation element 102 may have a mechanism to control the dirty outlet flow along second flow branch 124, such as a valve (not shown), to facilitate operation as filter pressure restriction increases over time due to loading of the filter 126 along the first flow branch 123.
As illustrated, the fluid pump 114 may be used to provide a fluid flow, such as fuel, from the fluid source 104, such as a bulk fuel storage tank, through the particle separation element 102 to a main fuel line 142. The particle separation element 102 may provide a main outlet flow along the main fuel line 142 using a first flow branch 143 to the fluid destination 106, such as a vehicle, and a secondary outlet flow containing certain particles to return to the fluid source 104 along a second flow branch 144 or to send to the fluid destination 108, such as a secondary storage tank. Non-limiting examples of particles include dirt and water droplets.
The particle separation element 102 may be positioned upstream or downstream of the fluid pump 114. In the illustrated embodiment, the particle separation element 102 is positioned downstream of the fluid pump 114. A filter 146 may be positioned downstream of the particle separation element 102 along the main fuel line 122. The filter 146, or fuel filter, may be configured to filter particles from gasoline or diesel fuel. The fluid system 120 may also include a fuel return line 128 from the fluid destination 106 to the fluid source 104. In other embodiments (not shown), the filter 146 may be positioned along, or another filter 146 may also be positioned along, the second flow branch 144, which may filter particles at a lower flowrate and pressure drop.
The particle separation element 102 may be configured to remove particles greater than a particular threshold size in diameter from the main fuel line 122 while the fluid pump 114 provides fuel at a particular flow rate appropriate for the fuel dispensing station and provide such particles to the second flow branch 144.
The outlet of the particle separation element 102 may be described as having two outlet flows: a “clean” outlet flow along the first flow branch 143 to main fuel line 142 and a “dirty” outlet flow along the second flow branch 144. The clean outlet flow may be predominately free of particles above the threshold size. The clean outlet flow may be sent to the filter 126 and ultimately the fluid destination 106, shown as a high-pressure common rail system. The dirty outlet flow may contain most of the particles above the critical size. The dirty outlet flow may be sent back the fluid source 104, shown as bulk fuel storage tank, or may be sent to the fluid destination 108, shown as a separate tank for containing the dirty or contaminated fuel. The particle separation element 102 may have a mechanism to control the dirty outlet flow along second flow branch 144, such as a valve (not shown), to facilitate operation as filter pressure restriction increases over time due to loading of the filter 146 along the first flow branch 143.
As illustrated, the fluid pump 114, such as a hydraulic pump, may be used to provide a fluid flow from the fluid source 104, such as a hydraulic fluid reservoir, through the particle separation element 102 to a main fluid line 162. The fluid source 104 may be in fluid communication with an inlet of the fluid pump 114. The particle separation element 102 may provide a main outlet flow along the main fluid line 162 using a first flow branch 163 to the fluid destination 106, such as a hydraulic component, which may include an actuator cylinder, and a secondary outlet flow containing certain particles to return to the fluid source 104 along a second flow branch 164. Non-limiting examples of particles include dirt, air bubbles, or water droplets. The fluid system 160 may also include a fluid return line 168 from the fluid destination 106 to the fluid source 104. The second flow branch 164 may be fluidly coupled to the fluid return line 168 before returning to the fluid source 104.
The particle separation element 102 may be positioned upstream or downstream of the fluid pump 114. In the illustrated embodiment, the particle separation element 102 is positioned downstream of the fluid pump 114. A hydraulic fluid filter 166 may be positioned downstream of the particle separation element 102 along the second flow branch 164, the fluid return line 168, or both. As illustrated, the second flow branch 164 and the fluid return line 168 are combined before reaching the filter 166. The filter 166 may be in fluid communication with the fluid source 104.
The outlet of the particle separation element 102 may be described as having two outlet flows: a “clean” outlet flow along the first flow branch 163 to main fluid line 162 and a “dirty” outlet flow along second flow branch 164. The clean outlet flow may continue to the fluid destination 106, shown as hydraulic components. The dirty outlet flow may combine with the fluid return line 168, which would go through the filter 166 before returning to the fluid source 104, shown as fluid reservoir. The particle separation element 102 may be designed to operate over the range of temperatures, flows, and system configurations (e.g. extension of a hydraulic cylinder).
As illustrated, the fluid pump 114, such as a hydraulic fluid pump, may be used to provide a fluid flow from the fluid source 104, such as a main hydraulic fluid reservoir, along a main fluid line 182 to the fluid destination 106, such as a hydraulic component, which may include an actuator cylinder. A return fluid flow may be provided from the fluid destination 106 to a nucleation filter 169 to nucleate air bubbles in the fluid along the fluid return line 188. The particle separation element 102 may be positioned downstream of the nucleation filter 169. The nucleation filter 169 may be in fluid communication with an inlet of the particle separation element 102 and the fluid destination 106. The particle separation element 102 may provide a main outlet flow along the fluid return line 188 using a first flow branch 183 to the fluid source 104 and a secondary outlet flow containing certain particles to the fluid destination 108, such as a settling reservoir or an aerated oil collection volume, along a second flow branch 184. The fluid destination 108 may be in fluid communication with the fluid source 104 with restricted flow to allow the aerated hydraulic fluid to collect and settle.
The fluid in a hydraulic fluid system 180 is pressurized by the fluid pump 114. The highly pressurized fluid can dissolve more air. When the fluid de-pressurizes in the fluid return line 188, the fluid can become super-saturated with air, which may lead to nucleation and formation of air bubbles in the fluid stream. The air bubbles may be removed before the fluid is picked up by the fluid pump 114 again. Air bubbles that reach the fluid pump 114 may cause cavitation, which may be loud and may damage the fluid pump. The nucleation filter 169 may be used to nucleate and grow air bubbles. The air-bubble-laden fluid may be sent through the particle separation element 102, which may include a hydrodynamic separator. The air bubbles may be concentrated into an “aerated oil return” outlet flow along the second flow branch 184. The aerated oil return outlet flow may be returned to the fluid destination 108, or settling reservoir, in a volume that allows for natural bubble settling. The fluid destination 108 may be a separate compartment in the same container as fluid destination 106. The “main return” along outlet flow, which does not have air bubbles, is sent to the fluid destination 106 along the fluid return line 188 and may be immediately available for the fluid system 180 to use.
As illustrated, the particle sensor 200 includes a light source 202, a light aperture 204, and a light detector 206. The controller 110 may operably connected to the light detector 206 and may also be operably connected to the light source 202.
The microfluidic channel 201 is configured to receive a flow of the fluid 208. The microfluidic channel 201 may have any suitable cross-sectional shape, such as rectangular, circular, or ovate. The particle sensor 200 may be configured to detect and characterize the particles 210, such as liquid droplets, air bubbles, dirt, metal, in the flow of the fluid 208 that may flow through the microfluidic channel 201.
The particles 210 may be dispersed in the fluid 208 in the microfluidic channel 201. For example, the particles 210 may be suspended in the fluid 208 in a separate phase or be made of a different composition or material. In other words, the particles 210, which may be liquid, are not dissolved in the fluid 208. In one example, the particles 210 may include a different fluid than the fluid 208.
In general, the microfluidic channel 201 is sized to receive one or more of the particles 210 at a time. In some embodiments, the microfluidic channel 201 has a cross-sectional area sized to receive one particle 210 of a predetermined size at a time. In particular, the cross-sectional area of the microfluidic channel 201 may be about the same size as a cross-sectional area of the particle 210, which may facilitate counting one particle 210 at a time to facilitate accurate counting and sizing of the particle 210.
The cross-sectional area may be defined orthogonal to the direction of the flow of the fluid 208. In other words, the cross-sectional area may be described as transverse to a longitudinal flow of the fluid 208. Cross-sectional area may be defined as a channel height (or depth) multiplied by a channel width. Both channel height and channel width may be orthogonal to the direction of the flow of the fluid 208. In some embodiments, the channel depth is less than or equal to the channel width. Using a relatively shallow channel depth may prevent the particles 210 from stacking between the light source 202 and the light detector 206, or hiding behind one another, as the particles flow through the microfluidic channel 201, which increases the opportunity for each particle to be detected.
Light Source
In the illustrated embodiment, the light source 202 is positioned outside of the microfluidic channel 201. At least one light aperture 204 is positioned between the light source 202 and the light detector 206. In some embodiments, the light aperture 204 is positioned before the microfluidic channel 201, for example, between the light source 202 and the microfluidic channel 201. In some embodiments, the light aperture 204 is positioned after the microfluidic channel 201, for example, between the microfluidic channel 201 and the light detector 206.
The light source 202 is configured to direct the light 212 through the light aperture 204 to form the light beam 214. The light beam 214 is directed to pass through the microfluidic channel 201. The light beam 214 may be collimated or substantially collimated by the light aperture 204, at least for the path length of the light beam 214 through the microfluidic channel 201. The light beam 214 may define a beam axis extending through the microfluidic channel 201. The walls of the microfluidic channel 201 may be formed of a light transparent material, at least to the light 212 provided by the light source 202.
The path of the light beam 214 intersecting with the microfluidic channel 201 defines the sensing area 216, which may also be described as a sensing volume, in which the particles 210 may be detected. After the light beam 214 passes through the microfluidic channel 201, the light beam 214 is received by the light detector 206, which may be positioned outside of microfluidic channel 201. When the particle 210 and fluid 208 are in the sensing area 216, the light detector 206 may be used to determine an absorbance of the light beam 214 by the particle 210 and the fluid 208 to detect, size, or otherwise characterize the particle 210.
As used herein, the term “path length” refers to the distance that light from the light source 202 travels in fluid to be measured. In some embodiments, the path length may be about equal to a width or depth of the microfluidic channel 201. The path length may be small to improve sensitivity to the particles 210. In some embodiments, the path length is less than or equal to 2000, 1000, 500, 300, 250, 200, 150, or 100 micrometers. In one or more embodiments, the path length is less than or equal to 1000 micrometers.
The light source 202 is configured to generate light in a selected frequency band such that the particle 210 has a different absorbance than the fluid 208 in the selected frequency band. In one or more embodiments, the particle 210 has a higher absorbance than the fluid 208, for example, when the liquid is water and fluid 208 is a hydrocarbon fluid. In fuel system applications, for example, the light source 202 may generate the light 212 in at least the near infrared (NIR) frequency band. In some embodiments, the NIR light 212 may include an emission peak in, or at least include frequencies in, a range from 1400 to 1600 nanometers. In particular, the NIR light 212 may include an emission peak centered at or near 1550 nanometers. In some embodiments, the NIR light 212 may include an emission peak in, or at least include frequencies in, a range from least 900 to 1100 nanometers. In particular, the NIR light 212 may include an emission peak centered at or near 1000 nanometers.
The light source 202 may include any suitable type of light source capable of providing the light 212 in a selected frequency band. In some embodiments, the light source 202 is a light-emitting diode (LED). The LED light source 202 may be a low-power LED. In some embodiments, the LED light source emit omnidirectionally or in all directions from the light-emitting junction. In some embodiments, the LED light source emits primarily in one direction. In some embodiments, the light source 202 may be paired with or include a fiber optic cable that directs light to the microfluidic channel 201. The light aperture 204 may be used to allow a narrow light beam 214 through the microfluidic channel 201, which may facilitate eliminating noise or false signals, for example, due to scattering and reflectance.
The light aperture 204 may be or include at least one opening in the aperture element 218. As used herein, “aperture” refers to the opening, or void, within the aperture element 218. The light aperture 204 may have a width that is sized relative to the microfluidic channel 201 and the light detector 206 to facilitate optimal sensitivity for detecting the particles 210 in the fluid 208. In some embodiments, a width of the light aperture 204 is the same or substantially the same as the channel width of the microfluidic channel 201.
Additionally, or alternatively, the light aperture 204 may be sized relative to a predetermined particle size of interest. For example, in some embodiments, a width of the light aperture 204 may be designed to be less than or equal to 2, 3, 4, 5, 6, 7, 8, 9, or 10 times the particle size of interest. In some embodiments, a width of light aperture 204 may be designed to be greater than or equal to 1, 2, 3, 4, 5, 6, 7, 8, or 9 times the particle size of interest.
The light aperture 204 may have any suitable geometric shape. In some embodiments, the light aperture 204 has a round or circular shape, such as a circle or oval. In some embodiments, the light aperture 204 has a polygonal shape, such as a triangle, square, trapezoid, or rectangle. The light aperture 204 may have a length, which may extend along the same direction as the flow of the fluid 208. In one or more embodiments, the length of the light aperture 204 may be the same or substantially the same as the width of the light aperture 204.
The light detector 206 may be any suitable type of photodetector sensitive to the selected frequency band, which may be an NIR frequency band. The light detector 206 is also configured to provide a signal representing an amount of light from the light beam 214 remaining after passing through the microfluidic channel 201. In particular, the light detector 206 may be configured to generate an electrical signal, such as a current, voltage, or power signal, in response to receiving light in the selected frequency band. Non-limiting examples of types of photodetectors include indium-gallium-arsenide (InGaAs), germanium (Ge), or silicon (Si) photodiodes. For example, an InGaAs photodiode may be sensitive to the light 212 in a frequency band from 1100 to 1700 nanometers. A Ge photodiode may have a peak sensitivity at 1550 nanometers. A Si photodiode may be used for visible light.
The controller 110 may be configured to detect, size, or otherwise characterize one or more particles 210 dispersed in the flow of fluid 208 based on the signal from light detector 206. In some embodiments, the controller 110 may be configured to detect one particle 210 at a time dispersed in the flow of the fluid 208, particularly particles of a predetermined size.
In general, when the particle 210 is a fluid, the particle may also be referred to as a droplet. When the particle 210 is a liquid, the signal may be used to determine an amount of liquid (e.g., water) per unit volume of the fluid 208 (e.g., hydrocarbon fluid) excluding liquid dissolved in the fluid.
In some embodiments, the controller 110 is configured to determine a particle rate through the sensing area 216. For example, a change in absorbance detected based on the signal from the light detector 206 may indicate that the particle 210 is entering or is leaving the sensing area 216. Alternatively, or additionally, the controller 110 may be configured to determine a particle size. In some embodiments, the controller 110 may determine a particle rate or a particle size based on at least one of: a magnitude of a pulse contained within the signal, a width of a pulse contained within the signal, a first threshold signal level for detecting a minimum size particle in the sensing area, a second threshold signal level for detecting a particle that fills the sensing area, and a threshold signal level crossing rate. When the particle is a fluid, the controller 110 may determine an amount of the particle 210 in droplet form per unit volume of fluid 208, such as a particle concentration, based on particle rate, particle size, or both. In some applications, such as non-engine applications, when a particle rate is regular or substantially regular, the particle rate may be used to estimate or determine a particle size or concentration.
In some embodiments, the controller 110 is further configured to determine an amount of the particles 210 in droplet form per unit volume of the fluid 208 based on the droplet rate and droplet size. The controller 110 may also be configured to determine a particle size based on the magnitude of a pulse contained within the signal data in response to the signal not crossing the second threshold signal level. The controller 110 may further be configured to determine a particle size based on the width of a pulse contained within the signal data in response to the signal crossing the second threshold signal level. Further, the controller 110 may be configured to determine a particle size based on the particle rate.
Capacitance-based sensor
In other embodiments, a capacitance-based sensor (not shown) may be used as the particle sensor 112. In order to detect single particles and assess fuel cleanliness, a capacitance sensor may be fabricated in the microfluidic channel 201, for example, near the outlet. Capacitance sensors may be used to detect particles 210, such as water or other liquid droplets or metal particles. The capacitance sensor may include interdigitated electrodes to form a flat capacitor. The capacitance of this channel may be calculated from:
where ϵf is the dielectric of the fluid in the microfluidic channel and l, w, and a are the geometric dimensions of the electrodes. When a particle passes through the microfluidic channel, the change in capacitance can be simplified to (approximately proportional to):
ΔC {tilde over (∝)} (ϵp−ϵf)Ap (Eq. 5)
where ϵp is the dielectric of the particle and Ap is the area of the particle.
Capacitance sensors can be used to sense a variety of particles in a fluid, for example, when the dielectric difference between the particle material and the fluid is sufficient to produce a significant signal. Table 1 below shows the dielectric constant for various particles and fluids. Particle materials having a larger difference in dielectric constant from the background fluid may produce a larger signal difference. In general, the signal may also be related to the particle size in addition to the dielectric difference between the particle and background fluid. In the case that the size is known (or approximately known), which may be determined by using the particle separation element 302 (see
The flow of fluid 208 and the particles 210 in the flow of the fluid may be received at the inlet 222. Any particles 210 may be detected by the particle sensor 112 positioned along the microfluidic channel 221 to provide signal data representing a signal corresponding to the fluid 208 and the particles 210 dispersed in the fluid. The controller 110 may be operably coupled to the particle sensor 112 to receive an indication that particles 210 have been detected.
The controller 110 may be operably coupled to a flow routing element 230 positioned along at least one flow branch 226, 228 of the outlet 224. In the illustrated embodiment, the flow routing element 230 includes a single valve 232 positioned between the first flow branch 226 and the second flow branch 228 to selectively divert fluid flow to one branch or the other branch. The controller 110 may be configured to control the flow routing element to direct fluid flow to the first flow branch 226, for example, until a threshold level of particles 210 is detected by the particle sensor 112 in the microfluidic channel 221. The controller 110 may also be configured to determine whether a threshold level of the particles 210 is present in the microfluidic channel 221 based on the signal data from the particle sensor 112. In response to determining that the threshold level of particles 210 is present in the microfluidic channel 221, the controller 110 may control the flow routing element 230 to direct fluid flow to the second flow branch 228.
The threshold level of particles 210 may be determined in any suitable manner. Non-limiting examples include detecting one or more particles above a threshold size, detecting a number of particles exceeding a threshold number, detecting a threshold rate (or frequency) of particles, or detecting a threshold concentration of particles in fluid.
The controller 110 may also determine a flow rate of the fluid 208 in the microfluidic channel 221. The flow rate may be used to determining an appropriate timing of when to control the fluid routing element 230 to direct fluid to the second flow branch 228 and a duration to control the fluid routing element to direct fluid back to the first flow branch 226.
The flow routing element 230 may include one, two, or more valves 232, solenoids, any other suitable mechanisms for diverting the flow of the fluid 208. In some embodiments (not shown), the flow routing element 230 includes two valves 232 each positioned along one of the flow branches 226, 228. The valves 232 may be alternatingly opened or closed to allow the fluid 208 to flow through the first flow branch 226 or the second flow branch 228.
In some embodiments, the arrangement 220 may be described as a water drop removal system or microfluidic water drop diverter system, which may be used for the removal of water drops, such as particle 210, from a hydrocarbon fluid. The diverter system may include a microfluidic drop diverter, or flow routing element 230, and the particle sensor 112 (for example, optical or capacitance types) that can detect individual water drops in the microfluidic channel 221. In the case that the microfluidic channel 221 contains a water drop the fluid may be diverted to a waste stream, such as second flow branch 228, via a valve switch or other mechanism, such as valve 232. The waste stream may be sent to a waste collection area, sent to a water removal filter (such as a barrier or coalescing filter), or returned to the main fuel tank. The time the fluid is diverted may be determined from the microfluidic channel geometry (such as dimensions and length between the sensor and diverter valve) and the flowrate. After the water drop is sent into the waste stream, the diverter valve may be switched such that the fluid is sent to the main outlet, such as first flow branch 226. The main outlet is considered clean (such as fuel without water drops) and may be sent to a particle removal filter, high pressure common rail system, or another part of the fuel system.
In another configuration, the microfluidic water drop diverter may include two valves. One valve may be in the main outlet channel, such as first flow branch 226, and the other may be in the waste outlet channel, or second flow branch 228. The valves may be close to the junction where the inlet flow channel, waste outlet channel, and main outlet channel meet, and thus incorporated into a microfluidic device. Alternatively, the valves may be away from the junction and independent of the microfluidic device (for example, in the tubing or piping leaving the device). When a water drop is sensed by the water drop sensor, the main outlet valve may close, and the waste outlet valve may open.
The diverter system may contain more than one microfluidic channel to increase total throughput. Multiple channels may or may not share the same particle sensor 112. The channel which contains the water drop maybe detected by having the sensor output be specific to that channel (see
The diverter system could also be used with a fuel system with two coalescing elements in parallel. When the water sensor positioned downstream of the first coalescing elements detects water, one or more valves may switch flow from the first coalescing element to the second coalescing element. This may allow drivers to switch filters at a longer interval or at a more convenient time.
The hydrodynamic separator 260 may be designed such that, at a predetermined flow rate of fluid 208, the microfluidic channel 241 is configured to direct any particles 210 exceeding a corresponding threshold size into the second flow branch 248 and any remaining particles into both the first flow branch 246 and the second flow branch 248 of the outlet 224.
The flow of fluid 208 and the particles 210 in the flow of the fluid may be received at the inlet 242. Any particles 210 may be detected by the particle sensor 112 positioned along the microfluidic channel 241 to provide signal data representing a signal corresponding to the fluid 208 and the particles 210 dispersed in the fluid. The controller 110 (
The controller 110 may be operably coupled to the fluid pump 114 (
The particle sensor 112a, b may be positioned in any suitable location along the microfluidic channel 241. In some embodiments, the particle sensor 112a, b may be positioned between the inlet 242 and the outlet 244. In some embodiments, the particle sensor 112a may be positioned closer to the inlet 242. Closer to the inlet 242, the particles 210 above the threshold size may not be focused along an inner wall 262 of the hydrodynamic separator 260. The particle sensor 112a may define a sensing area (illustrated schematically in solid line) that covers most or all of the width of the microfluidic channel 241 from the inner wall 262 to an outer wall 264. Closer to the outlet 244, the particles 210 above the threshold size may be focused along the inner wall 262 of the hydrodynamic separator 260. A particle sensor 112b positioned towards the outlet 244 may define a sensing area (illustrated schematically in solid line) that covers some or less than half of the width of the microfluidic channel 241 from the inner wall 262 to the outer wall 264.
In general, when a droplet is sensed, the arrangement 240 may change the fluid flow to focus the droplet into the waste stream. The flow may be calibrated to remove specific sized droplets or particles based on sizing information from the particle sensor 112a, b. The flow could be changed with a pressure pulse, dip, or changes to the flow paths (such as opening or changing a valve position of one or more valves positioned at the outlet 244).
In some embodiments, the waste stream, such as the second flow branch 248, may be only a fraction of the size of the overall flow stream. This may minimize the impact to the overall flow stream when removing the droplets.
In the illustrated embodiment, the particle separation element 302 is configured to sort the particles 210 in a first size range, a second size range, and a third size range into a first outlet flow 304 (containing particles in the first size range, second size range, and third size range), a second outlet flow 306 (containing particles in the second size range and third size range), and a third outlet flow 308 (containing particles in the third size range) for sensing by the microfluidic sensing element 116. The particle sensor 112 may be positioned along the microfluidic sensing element 116 to detect the number of particles in each outlet flow 304, 306, 308. The controller 110 (
As can be seen in
The second flow branch 328 of the first hydrodynamic separator 320 may be configured to provide the first outlet flow 304. The second flow branch 332 of the second hydrodynamic separator 322 may be configured to provide the second outlet flow 306. The first flow branch 330 of the second hydrodynamic separator 322 may be configured to provide the third outlet flow 308. The first flow branch 326 of the first hydrodynamic separator 320 may be in fluid communication, or fluidly coupled to, the inlet of the second hydrodynamic separator 322 to provide a fourth fluid flow 310.
The first hydrodynamic separator 320 may be configured to focus all particles in the first size range into the second flow branch 328. The first size range may include any particles exceeding a first threshold size. Any remaining particles that do not exceed the first threshold size may be provided to both the first flow branch 326 and the second flow branch 328. The remaining particles may be considered uniformly distributed. The ratio of remaining particles provided to each branch 326, 328 may be determined based on the volume fractions associated with each branch 326, 328. In general, the first flow branch 326 may receive a first portion, and the second flow branch 328 may receive a second portion of any remaining particles that do not exceed the first threshold size. As can be seen in
None of the other outlet flows 306, 308 contain particles that exceed the first threshold size.
The second hydrodynamic separator 322 may receive the flow from the first branch 326 including the second portion of any remaining particles that do not exceed the first threshold size. The second hydrodynamic separator 322 may be configured to focus all particles in the second size range into the second flow branch 332. The second size range may include any particles exceeding a second threshold size. Any remaining particles that do not exceed the second threshold size may be provided to both the first flow branch 330 and the second flow branch 332, which may be only particles in the third size range. The remaining particles may be considered to be uniformly distributed. The ratio of remaining particles provided to each branch 330, 332 may be determined based on the volume fractions associated with each branch 330, 332. In general, the first flow branch 330 may receive a first portion, and the second flow branch 332 may receive a second portion of any remaining particles that do not exceed the second threshold size. As can be seen in
The microfluidic sensing element 116 may be in fluid communication with the particle separation element 302. The microfluidic sensing element 116 may include a plurality of microfluidic channels 340, which may be described as microfluidic sensing channels, each in fluid communication with a different flow branch of the particle separation element 302. The microfluidic channels 340 may be arranged in parallel. In particular, each microfluidic channel 340 receives a different outlet flow 304, 306, 308. The particle sensor 112 may be positioned and configured to detect the number of particles flowing through each of the microfluidic channels 340.
The controller 110 may determine the number of particles in each size range by counting the number of particles of any size range in each outlet flow 304, 306, 308 in the microfluidic channels 340. For illustrative purposes, assuming that the volume fraction between each pair of flow branches is 1:1 and the number of remaining particles (the number of particles that do not exceed the particle threshold size) is divided evenly between the two branches, the number of particles in each outlet flow may be calculated as follows:
where n1 is the first size range, n2 is the second size range, n3 is the third size range, d1 is the first threshold size, d2 is the second threshold size, c1 is the number of particles counted in the first outlet flow 304, c2 is the number of particles counted in the second outlet flow 306, and c3 is the number of particles counted in the third outlet flow 308.
In general, the inlet of the particle separation element 302 may receive a random distribution of the particles 210. The particle separation element 302 may sort the particles 210 into different outlet flows 304, 306, 308. The outlet flows 304, 306, 308 may be received by a microfluidic sensing element 116. The particle sensor 112 may count the number of particles in each microfluidic channel 340 of the microfluidic sensing element 116 and determine the number of particles in each size range.
In some embodiments, the particle sensor 112 may include a detector aligned to each microfluidic channel 340 to count the number of particles in each channel. In other embodiments, the particle sensor 112 may use a shared detector across multiple channels to count the number of particles in each channel.
The arrangement 300 may be described as a microfluidic particle sensor, which may be used to measure fluid cleanliness level in liquid applications. In one example, the microfluidic particle sensor may be used in diesel fuel filtration systems to measure fluid cleanliness. The sensor may be placed upstream of a filter, downstream of a filter, or as a bypass to a filter. The sensor may include a segmentation stage, or particle separation element 302, that divides the particles into streamlines, for example, based on ISO cleanliness codes, which may include particles from 4 to 6 micrometers in a first stream, particles from 6 to 14 micrometers in a second stream, and particles greater than 14 micrometers in a third stream. Particle sizes under 4 micrometers may not be counted, or an additional stage may be added (equal four stages) to capture particles under 4 micrometers, from 4 to 6 micrometers, from 6 to 14 micrometers, and greater than 14 micrometers. The microfluidic particle sensor may also be used in hydraulic or lube applications.
The sensor may be described as having two stages. The first stage may be described as a “segregator stage,” such as the particle separation element 302, which focuses particles into specific streamlines based on the particle size. The second stage may be described as a “sensing stage” including multiple sensing channels, such as microfluidic sensing element 116, in which specific particulate containing streamlines are sent into different channels. Each individual channel has a particle sensor or particle counter. The design of the segregator stage may dictate which particle size range goes into each channel. By counting or otherwise detecting particles in a sensing channel a particle size distribution may be determined.
Once particles have been focused into streamlines based on their particle size, the streamlines may be sent into different sensing channels, such as microfluidic channels 340. Each sensing channel corresponds to a particle size range (based on the design and performance of the segregator stage). Each sensing channel may be associated with a particle sensor. The particle sensor may detect, or count, the passage of a particle in the sensing channel. The particle sensor may be optical (using light absorbance, fluorescence, scattering, or other optical methods), electronic (using capacitance sensor or impedance sensor), or magnetic. The sensing channels may share a single particle sensor when the signal output from each channel is unique.
Such a microfluidic particle sensor using a passive particle focusing scheme upstream of particle counters may not require calibration as the particles are counted. This may allow for ease of manufacturing. The microfluidic particle sensor may also be designed to work over a range of different types of particles that have different properties, such as electronic or magnetic properties. The microfluidic particle sensor may also count individual particles one-by-one, instead of a bulk fluid reading, which may lead to increased sensitivity. The use of microfluidic channels may also minimize the effect of the background or carrier fluid.
The controller 110 (see
In general, the unique spacing patterns provide different time profiles for a drop moving through a particular microfluidic sensing channel 340a, 340b, 340c. In the illustrated embodiments, a series of holes are placed at different distances to each other, such that a drop moving through the channel will give several signal dips and the temporal pattern of the dips is specific to the channel. A unique signal may also be created with an orifice pattern that gives a different signal profile (such as different shaped orifice holes). Unique spacing and unique shapes may also be used together. In the case that multiple drops are present in the channels, signal deconvolution algorithms may be used to distinguish individual channels.
In some embodiments, a diffraction grating may also be used to control the light entering the channels. The diffraction grating may be in the channel or enclosed in the channel and direct the optical path towards a specific detector in an array of detectors.
While the present disclosure is not so limited, an appreciation of various aspects of the disclosure will be gained through a discussion of the specific examples and illustrative embodiments provided below, which provide particle separation to supplement or replace filters. Various modifications of the examples and illustrative embodiments, as well as additional embodiments of the disclosure, will become apparent herein.
As illustrated, the fluid pump 114 may be used to provide a fluid flow from the fluid source 104 through the particle separation element 102 to the main flow line 362. The particle separation element 102 may provide a main outlet flow using the first flow branch 363 and a secondary outlet flow using the second flow branch 364. The first flow branch 363 and the second flow branch 364 may be recombined along the main flow line 362 upstream of the fluid destination 106, which may include the rest of the system 360.
The secondary outlet flow may be provided to a filter 366 along the second flow branch 364 upstream of recombination with the main outlet flow. Optional filters 368 may be positioned, for example, along the first flow branch 363 upstream of recombination or along the main flow line 362 downstream of recombination.
The particle separation element 102 may be positioned upstream or downstream of the fluid pump 114. In the illustrated embodiment, the particle separation element 102 is positioned downstream of the fluid pump 114.
The particle separation element 102 may be configured to remove particles greater than a particular threshold size in diameter from the main flow line 362 while the fluid pump 114 provides fluid at a particular flow rate.
The separator element 102 can be used to focus particles above a particular threshold size into a portion of the total fluid flow. The concentrated particle stream may be focused, or directed, into the secondary outlet flow along the second branch 364, which may be provided to the filter 366, which may be described as a dead-end filter, to remove particles. After going through the filter 366, fluid from the concentrated particle stream from the second flow branch 364 may be combined with the remainder of the fluid from the first flow branch 363 and delivered to the rest of the system shown as the fluid destination 106. Particles above the critical size may be largely removed from the overall fluid provided to the fluid destination 106.
In the system 360, only a portion of the total fluid flow is filtered through the filter 366. In some embodiments, the concentrated particle stream provided to the second flow branch 364 may include less than 50% of the total fluid volume, less than 25% of the total fluid volume, or less than 10% of the total fluid volume. The flow rate through the filter 366 may be lower than, for example, in systems where the particle separation element 102 were not used. The lower flow rate may lead to a lower filter pressure drop, longer filter life, or both.
Additional filters 368 may be used to remove particles below the critical size, for example, along the “clean stream” line along the first flow branch 363, or along the main flow line 362, after the fluid streamlines combine. A flow metering, or variable pressure object, in the clean stream along the first flow branch 363, may be used to balance flow appropriately between the two streams exiting the separator element 102.
The technique of coupling the separator element 102 to a filter may be used in a number of applications, such as engine fuel, engine oil, engine hydraulic, and stationary hydraulic. This technique may be particularly useful in engine oil, engine hydraulic, or stationary hydraulic, where the fluid is re-circulated through the filter system.
In Example 1, hydrodynamic separators were fabricated as microfluidic devices from polydimethylsiloxane (PDMS) using standard soft photolithography techniques. In brief, a photomask was prepared using DraftSight and printed at 20,000 dpi (CAD/Art Services, Inc.; Brandon, Oregon). The SU-8 mold was prepared using SU-8 2100 photoresist (MicroChem, Inc.; Newton, Mass.). Process parameters are described on the SU-8 2100 datasheet provided by MicroChem. PDMS (Sylguard 184; Dow Corning; 10:1 w/w base: curing agent) was poured over the mold, degassed for 30 minutes, and cured in an oven overnight at 85° C. After removing the PDMS from the wafer, inlet and outlet holes were punched with biopsy needles. Scotch tape was used to remove particles and fibers from the PDMS. The final device was prepared by plasma bonding the PDMS to a glass slide using a Harrick Plasma cleaner at 800 micron (mtorr) for 1 minute. The finished device was placed on a hotplate at about 100° C. for 15 minutes. Devices were designed with a constant radius of curvature, channel width, and channel depth.
In Example 2, fluorescent particles were suspended in de-ionized water for testing (Table 1). The 2, 10, and 20 micrometer (μm) particles were provided in an aqueous suspension. These samples were diluted and tested directly.
The 25 μm and 30 μm particles were provided as a powder. These samples were added with sodium dodecyl sulfate surfactant (SDS) to de-ionized water to prepare the testing solution.
A typical mixture contained 50 mg of particles, 100 mg of SDS, and 500 mL of de-ionized water. Particle size distributions were confirmed with a laser diffraction particle sizer (Beckman-Coulter LS-320).
Particles were fed to hydrodynamic separators, made according to Example 1, using a pressure driven flow system (ElveFlow OB1-Mk3; Elvesys; Paris, France). The system contained an in-line flowmeter to measure the flow in real time (Elveflow FS4 (0-1 mL/min) or FS5 (0.2-5 mL/min); Elvesys; Paris, France). The flow was controllable by pressure or by flowrate within the ESI Software package.
Particle focusing within the hydrodynamic separators was measured optically using an Olympus IX-73 inverted microscope (Olympus Life Science; Waltham, MA) coupled with a mercury vapor short arc lamp (U-HGLGPS, Olympus Life Science; Waltham, Mass.). A fluorescence filter cube was selected to match the absorbance and emission characteristics of the fluorescent particles. Images were taken with a 10× objective. Images were captured using a Prime BSI sCMOS camera (Teledyne Photometrics; Tuscan, Ariz.) using MicroManager (version 1.4; https://micro-manager.org/wiki/Micro-Manager).
Prior to injecting particles, a pressure-flow calibration was determined for each hydrodynamic separator using de-ionized (DI) water, to calibrate for unreliable flowmeter readings for particle containing solutions. The data was fit to a second order polynomial and used to determine operating pressures for desired experimental flowrates.
During particle experiments the system pressure was controlled, and the pressure-flow data was recorded. If the pressure-flow data showed decay over the experimental timeframe, an assumption was made that particles were collecting somewhere in the device and the data was not recorded.
After the experiment, the device was cut in half and the channel depth was measured optically on the Keyence VHX Digital Microscope (Keyence; Itasca, Ill.).
Once the pressure-flow relationship of a device was calibrated, an experiment was run at a constant Dean Number, or flow rate, with a single fluorescent particle solution. Fluorescence images were taken at various angles through the device to measure particle focusing as a function of length (L=αRc, where α is the angle through the device in radians and R is the radius of curvature measured at the inside wall). The angles were defined around the circular shape of each hydrodynamic separator, for example, as shown in
The extent of particle focusing was determined using image analysis in ImageJ open source software. Pixel intensity was measured across the channel at each imaged location of the device. The pixel intensity is assumed to be proportional to average particle concentration. The location of particle focusing was determined from the outlet image (340° or 350°). For each image, the percent focusing was determined as the ratio of the integrated pixel intensity in the focused region to the integrated pixel intensity of the entire channel as follows:
In Example 3, 25 μm particles were focused in a hydrodynamic separator (channel width: 500 μm, channel depth: 140 μm, radius of curvature: 20 mm) at two Dean numbers. A plot 410 showing the percent focused versus channel length data is shown in
At the device inlet, the particles are about 35% focused. The amount of focusing does not increase for the first 14 mm of channel length, which may be due to particle migration from the center of the channel to the edges of the channel due to shear-lift forces. This region 412 of the device may be described as the particle migration region and has a length L0. This length may depend on particle size, fluid properties, and flow rate.
After the particle migration region, the percent of particles that are focused may increase linearly with respect to channel length. This region 414 of the device may be described as the linear focusing region. The slope of the linear fit may be described as the linear focusing rate (rf). The percent of particles focused generally increases linearly until a maximum value.
Once the maximum value of particle focusing is reached, the particle focusing may stay approximately constant. This region 416 of the device may be described as the fully focused region. In this example, the maximum focusing percentage (fm) in the fully focused region shows is about 90% (that is, 90% of the particles are focused).
The length of the hydrodynamic separator that may be used to reach a target focusing percentage may be described as:
Table 3 shows data for focusing experiments with the same device run at different Dean Numbers. The length of the particle migration region and the length required to reach 90% focusing are similar and nearly identical.
Experiments with Same Dean Number, Different Device (104 μm Depth: 30 μm Particles)
In Example 4, a similar experiment to Example 3 was run with approximately the same Dean Numbers but on devices with two different radii of curvatures. 30 μm particles were used. The results from the experiment are shown in Table 4. The length of the particle migration region was shorter for the device with the smaller radius of curvature. In addition, the linear focusing rate was higher for the device with the smaller radius of curvature. Based on these results, the length required to focus particles to 50%, for example, was shorter for the device with the smaller radius of curvature.
In general, the device with the smaller radius of curvature may achieve a target Dean Number with a lower flowrate than a device with a larger radius of curvature. When comparing the pressure drop required to focus particles, a smaller radius of curvature may result in a shorter channel and a lower flowrate, which may have a large impact on pressure drop.
As an example, from the data in Table 4 and the applied experimental pressures, the pressure drop associated with a hydrodynamic separator designed to focus 50% of the particles was calculated from the following equation:
where Papp is the experimentally applied pressure, LD is the length required to reach 50% focusing (Table 4), Rc is the device radius of curvature (Table 4), and the term
accounts for the experimental device design in which the device only covered 350° of circle arc-length to allow for inlet and outlet ports. The calculated pressure drops are shown in Table 4. The device with a smaller radius of curvature was used to focus particles at a much lower pressure drop.
It has recently been discovered that the length of the linear focusing region required to achieve maximum particle focusing (85%-95% particle focusing) may be described by the following relation:
where Re is the Reynolds Number, De is the Dean Number, and DH is the hydraulic diameter of the hydrodynamic separator, w is the channel width, and Rc is the radius of curvature of the hydrodynamic separator. More specifically, the relationship is the following:
Furthermore the length of the linear focusing region required to achieve maximum particle focusing for a specific particle size may be described by the following relation:
Where a is the particle diameter. Particle diameter can be the equivalent spherical diameter for particles having a sphericity greater than 0.5. This equation can be a predictor of the length of the linear focusing region for particles having a diameter greater than 8% of the channel hydraulic diameter and less than or equal to 50% of the channel height.
The total length for a hydrodynamic separator may be determined or calculated to be:
L
D
=L
0
+L
f (Eq. 13)
This equation may be used to calculate the minimum hydrodynamic separator channel lengths necessary to achieve maximum particle focusing for various applications. Experimental results demonstrate that the length of the particle migration region L0 ranges from 0% to 29% of the total length of the hydrodynamic separator LD necessary to achieve maximum particle focusing. Further, data shows that the length of the particle migration region Lo ranges from 0% to 40% of the length of the linear focusing region Lf. As such, the hydrodynamic separator channel length LD may be greater than or equal to the length of the length of the linear focusing region Lf to achieve maximum particle focusing. The hydrodynamic separator channel length LD may be no greater than 40% more than the length of the linear focusing region Lf to achieve particle focusing that is balanced with minimizing the pressure drop across the channel.
Some embodiments relate to a hydrodynamic separator.
In Embodiment A1, a system comprises:
In Embodiment A2, a system includes the system according to Embodiment A1, wherein the particle sensor comprises:
In Embodiment A3, a system includes the system according to Embodiment A1, wherein the particle sensor comprises a capacitance sensor.
In Embodiment A4, a system includes the system according any preceding A embodiment, further comprising a source reservoir in fluid communication with the inlet and second flow branch, wherein the fluid and the particles are pumpable from the source reservoir to the hydrodynamic separation element and selectively back to the source reservoir through the second flow branch.
Some embodiments relate to a particle diverter.
In Embodiment B1, a system comprises:
In Embodiment B2, a system comprises the system according to Embodiment B1, wherein the particle separation element comprises a hydrodynamic separator element including one or more hydrodynamic separators, the one or more hydrodynamic separators comprising the one or more microfluidic channels, wherein each microfluidic channel is curved.
In Embodiment B3, a system comprises the system according to Embodiment B1 or B2, wherein the particle sensor comprises:
In Embodiment B4, a system comprises the system according to Embodiment B1 or B2, wherein the particle sensor comprises a capacitance sensor.
In Embodiment B5, a system comprises the system according to any preceding B embodiment, further comprising a source reservoir in fluid communication with the inlet and second flow branch, wherein the fluid and the particles are pumpable from the source reservoir to the hydrodynamic separation element and selectively back to the source reservoir through the second flow branch.
Some embodiments relate to a particle sorter.
In Embodiment C1, a system comprises:
In Embodiment C2, a system comprises the system according to Embodiment C1, wherein the plurality of microfluidic separation channels comprises a third hydrodynamic separator in fluid communication with the first flow branch of the second hydrodynamic separator.
In Embodiment C3, a system comprises the system according to Embodiment C1 or C2, further comprising:
In Embodiment C4, a system comprises the system according to Embodiment C3, wherein at least one microfluidic separation channel comprises an outlet comprising a first outlet branch and a second outlet branch, further comprising at least one flow routing element positioned along the outlet of the at least one microfluidic sensing channel, wherein the controller is operably coupled to the at least one flow routing element and further configured to control the flow routing element to direct fluid flow to the second outlet branch in response to detecting particles in the corresponding microfluidic sensing channel.
In Embodiment C5, a system comprises the system according to Embodiment C3 or C4, wherein the particle sensor comprises a capacitance sensor.
In Embodiment C6, a system comprises the system according to Embodiment C3 or C4, wherein the particle sensor comprises:
In Embodiment C7, a system comprises the system according to Embodiment C6, wherein the aperture element comprises a plurality of light apertures including the light aperture positioned in the path of the light beam from the light source, wherein the plurality of light apertures comprises a different set of light apertures aligned to each microfluidic sensing channel, wherein each set of light apertures defines a unique spacing pattern along the corresponding microfluidic sensing channel, and wherein the light detector is positioned to receive the light beam in the sensing area after passing through the plurality of light apertures and the plurality of microfluidic sensing channels, and wherein the controller is configured determine the number of particles associated with each size range based on the unique spacing pattern.
Some embodiments relate to orifice patterns.
In Embodiment D1, a system comprises:
In Embodiment D2, a system comprises the system according to Embodiment D1, wherein each microfluidic sensing channel is configured to receive particles in a different size range and the controller is further configured to determine a number of particles associated with each size range.
In Embodiment D3, a system comprises the system according to Embodiment D1 or D2, further comprising a hydrodynamic separation element positioned upstream of the plurality of microfluidic sensing channels, the hydrodynamic separation element comprising a plurality of hydrodynamic separators in series fluid communication including at least a first hydrodynamic separator and a second hydrodynamic separator each defining a curved microfluidic separation channel to separate particles of different size ranges, each microfluidic separation channel defining:
In Embodiment D4, a system comprises the system according to Embodiment D3, wherein the controller is further configured to determine a number of particles associated with each size range based on volume fractions associated with the flow branches based on signal data.
In Embodiment D5, a system comprises the system according to Embodiment D3 or D4, wherein the controller is operably coupled to a fluid pump in fluid communication with the hydrodynamic separation element, the controller configured to control the fluid pump to direct fluid at the particular flow rate through the hydrodynamic separation element.
In Embodiment D6, a system comprises the system according to any one of Embodiments D3 to D5, wherein at least one microfluidic sensing channel comprises an outlet comprising a first outlet branch and a second outlet branch, further comprising at least one flow routing element positioned along the outlet of the at least one microfluidic sensing channel, wherein the controller is operably coupled to the at least one flow routing element and further configured to control the flow routing element to direct fluid flow to the second outlet branch in response to detecting particles in the corresponding microfluidic sensing channel.
Some embodiments relate to water drop detection.
In Embodiment E1, a system comprises the system according to any A embodiment, any B embodiment, any one of Embodiments C4 to C8, or any D embodiment, wherein the particles comprise a second fluid different than the fluid.
In Embodiment E2, a system comprises the system according to Embodiment E1, wherein the controller is further configured to determine an amount of the second fluid in droplet form per unit volume of the fluid based on the signal data.
In Embodiment E3, a system comprises the system according to Embodiment E2, wherein the amount excludes the second fluid dissolved in the fluid.
In Embodiment E4, a system comprises the system according to any preceding E embodiment, wherein the controller is configured to determine a droplet rate or a droplet size of one or more droplets of the second fluid dispersed in the flow of the fluid based on the signal data.
In Embodiment E5, a system comprises the system according to Embodiment E4, wherein the controller is configured to determine the droplet rate or the droplet size based on at least one of:
In Embodiment E6, a system comprises the system according to Embodiment E5, wherein the controller is further configured to determine at least one of:
In Embodiment E7, a system comprises the system according to any preceding E embodiment, wherein the fluid comprises a hydrocarbon fluid and the second fluid comprises water.
Some embodiments relate to an engine fuel system.
In Embodiment F1, a system comprises:
In Embodiment F2, a system comprises the system according to Embodiment F1, wherein the particles comprise water droplets dispersed in the fuel.
In Embodiment F3, a system comprises the system according to Embodiment F1 or F2, further comprising a fuel tank in fluid communication with each inlet and in fluid communication with each second flow branch.
In Embodiment F4, a system comprises the system according to any preceding F embodiment, further comprising a fuel filter configured to filter particles from gasoline or diesel fuel positioned along the fuel line.
In Embodiment F5, a system comprises the system according to any preceding F embodiment, further comprising a fuel pump in fluid communication with the fuel line, wherein the fuel pump is configured to provide fuel flow to the fuel injector system along the fuel line, wherein the fuel injector system comprises a high-pressure common rail.
Some embodiments relate to a bulk fuel system.
In Embodiment G1, a system comprises:
In Embodiment G2, a system comprises the system according to Embodiment G1, further comprising the bulk fuel storage tank to store fuel in fluid communication with the inlet and optionally in fluid communication with the second flow branch.
In Embodiment G3, a system comprises the system according to Embodiment G1 or G2, further comprising a secondary storage tank to store fuel in fluid communication with the second flow branch.
In Embodiment G4, a system comprises the system according to any preceding G embodiment, further comprising a fuel filter configured to filter particles from gasoline or diesel fuel positioned along the fuel line.
In Embodiment G5, a system comprises the system according to any preceding G embodiment, further comprising a fuel pump in fluid communication with the fuel line, wherein the fuel pump is configured to provide fuel flow to the fuel vehicle fuel tank along the fuel line.
Some embodiments relate to a hydraulic particle filter.
In Embodiment H1, a system comprises:
In Embodiment H2, a system comprises the system according to Embodiment H1, further comprising a hydraulic fluid filter to filter particles from hydraulic fluid positioned along a hydraulic fluid return line in fluid communication between the second flow branch and a hydraulic fluid reservoir, the hydraulic fluid reservoir in fluid communication with an inlet of the hydraulic pump.
Some embodiments relate to enhancing hydraulic deaeration.
In Embodiment I1, a system comprises:
In Embodiment I2, a system comprises the system according to Embodiment I1, wherein the particles comprise air bubbles.
In Embodiment I3, a system comprises the system according to Embodiment I2, further comprising a nucleation filter to nucleate air bubbles in the hydraulic fluid in fluid communication between the hydraulic component and the inlet.
In Embodiment I4, a system comprises the system according to Embodiment I3, further comprising:
Thus, various embodiments of systems and methods for separating particles in hydrocarbon fluids are disclosed. Although reference is made herein to the accompanying set of drawings that form part of this disclosure, one of at least ordinary skill in the art will appreciate that various adaptations and modifications of the embodiments described herein are within, or do not depart from, the scope of this disclosure. For example, aspects of the embodiments described herein may be combined in a variety of ways with each other. Therefore, it is to be understood that, within the scope of the appended claims, the claimed invention may be practiced other than as explicitly described herein.
All references and publications cited herein are expressly incorporated herein by reference in their entirety for all purposes, except to the extent any aspect directly contradicts this disclosure.
All scientific and technical terms used herein have meanings commonly used in the art unless otherwise specified. The definitions provided herein are to facilitate understanding of certain terms used frequently herein and are not meant to limit the scope of the present disclosure.
Unless otherwise indicated, all numbers expressing feature sizes, amounts, and physical properties used in the specification and claims may be understood as being modified either by the term “exactly” or “about.” Accordingly, unless indicated to the contrary, the numerical parameters set forth in the foregoing specification and attached claims are approximations that can vary depending upon the desired properties sought to be obtained by those skilled in the art utilizing the teachings disclosed herein or, for example, within typical ranges of experimental error.
The recitation of numerical ranges by endpoints includes all numbers subsumed within that range (e.g. 1 to 5 includes 1, 1.5, 2, 2.75, 3, 3.80, 4, and 5) and any range within that range. Herein, the terms “up to” or “no greater than” a number (e.g., up to 50) includes the number (e.g., 50), and the term “no less than” a number (e.g., no less than 5) includes the number (e.g., 5).
Terms related to orientation, such as “upstream” and “downstream” are used to describe relative positions of components and are not meant to limit the absolute orientation of the embodiments contemplated.
The terms “coupled” or “connected” refer to elements being attached to each other either directly (in direct contact with each other) or indirectly (having one or more elements between and attaching the two elements). Either term may be modified by “operatively” and “operably,” which may be used interchangeably, to describe that the coupling or connection is configured to allow the components to interact to carry out functionality.
As used herein, the term “configured to” may be used interchangeably with the terms “adapted to” or “structured to” unless the content of this disclosure clearly dictates otherwise.
The term “or” is generally employed in its inclusive sense, for example, to mean “and/or” unless the context clearly dictates otherwise. The term “and/or” means one or all of the listed elements or a combination of at least two of the listed elements.
The phrases “at least one of,” “comprises at least one of,” and “one or more of” followed by a list refers to any one of the items in the list and any combination of two or more items in the list.
This application claims the benefit of U.S. Provisional Application No. 62/942,009, filed 29 Nov. 2019, the disclosure of which is incorporated by reference herein in its entirety.
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/US2020/062401 | 11/25/2020 | WO |
| Number | Date | Country | |
|---|---|---|---|
| 62942009 | Nov 2019 | US |
