Claims
- 1. A granulate containing, as active ingredient mesna, in combination with, for each part by weight of mesna: 0.1-1 parts by weight of a binding agent.
- 2. A granulate as set forth in claim 1 containing a member of the group consisting of: 0.01-0.2 parts by weight of a lubricant and 0.1-1 parts by weight of a filling agent.
- 3. A granulate as set forth in claim 1 or claim 2 containing at least one member of the group consisting of flavoring, sweetening and aromatizing substance.
- 4. A granulate according to claim 1 or claim 2 which is coated with a conventional pharmaceutically-acceptable film.
- 5. A process for the manufacture of a granulate containing, as active substance mesna, in combination with, for each part by weight of mesna: 0.01-1 parts by weight of a binding agent said process including the step of granulating mesna and at least a portion of said binding agent with at least one member of the group consisting of C.sub.1 -C.sub.4 -alcohols and acetone or a mixture of at least one of said organic agents with water.
- 6. A process as set forth in claim 5 in which there is present, during the granulation,
- 0.1-1 parts by weight of a filling agent and/or
- 0.1-0.2 parts by weight of a lubricant.
- 7. A process as set forth in claim 5 or claim 6 including the step of drying the granulate.
- 8. A process as set forth in claim 7 including applying a pharmaceutically-acceptable coating to the dried granulate.
- 9. As set forth in claim 5 or claim 6 including the step of drying the granulate, adding a member of the group consisting of flavoring, sweetening and aromatizing agents and homogenizing the entire mixture.
- 10. A process as set forth in claim 9 including applying a pharmaceutically acceptable coating to the homogenized pro duct.
Priority Claims (1)
Number |
Date |
Country |
Kind |
4022525 |
Jul 1990 |
DEX |
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Parent Case Info
This is a division of Application No. 07/730,178, filed Jul. 16, 1991, pending
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4959215 |
Sauerbier et al. |
Sep 1990 |
|
5155108 |
Miyake et al. |
Oct 1992 |
|
Divisions (1)
|
Number |
Date |
Country |
Parent |
730178 |
Jul 1991 |
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