Tailoring Recruitment Communication using Virtual Human Technology to Increase Participation of Older Minority Adults in Clinical Trials

Information

  • Research Project
  • 10332981
  • ApplicationId
    10332981
  • Core Project Number
    R24AG074867
  • Full Project Number
    1R24AG074867-01
  • Serial Number
    074867
  • FOA Number
    PAR-18-749
  • Sub Project Id
  • Project Start Date
    9/30/2021 - 4 years ago
  • Project End Date
    8/31/2024 - a year ago
  • Program Officer Name
    ELLIOTT, CERISE
  • Budget Start Date
    9/30/2021 - 4 years ago
  • Budget End Date
    8/31/2022 - 3 years ago
  • Fiscal Year
    2021
  • Support Year
    01
  • Suffix
  • Award Notice Date
    9/21/2021 - 4 years ago
Organizations

Tailoring Recruitment Communication using Virtual Human Technology to Increase Participation of Older Minority Adults in Clinical Trials

PROJECT SUMMARY Older adult minorities are an underserved population, who are at a particularly high risk for developing chronic diseases/health conditions and are significantly underrepresented in clinical research. Well-known barriers, including research-related mistrust (e.g., belief that participants lack choice, mistrust of white researchers), lack of cultural diversity/sensitivity among CT staff, and the exclusion of decisional support providers in decision- making impede older adult minority participation in CTs. Tailoring content and source preferences to be patient- centered, culturally sensitive (i.e., promote feelings of comfort, trust, respect), and personally relevant to the receiver (a patient), thus increasing the likelihood of having a lasting effect on their attitudes and behaviors, has been linked to positive health behaviors by older adult minorities. Such tailoring has not been studied to increase participation rates of older adult minorities into active CTs, though culturally tailored VHT interventions are perceived as trustworthy among minority participants. Our long-term goal is to increase clinical trial (CT) participation among older adult minorities (Black/African American (AA), Hispanic/Latinx (H/L), and/or rural adults over the age of 50) using Virtual Human Technology (VHT). In Aim1, we will conduct focus groups with older adult minorities to obtain data that will be used to redesign ALEX to be culturally sensitive for these minorities. In Aim 2, track engagement of such minorities into active, NIH-funded CTs across different modalities for remotely delivering ALEX. In Aim 3, we will compare ALEX and standard recruitment methods for enrolling such minorities into NIH-funded CTs. Achievement of these project aims will result in adaptable, minimally tailored VHT recruitment intervention for increasing older adult minority participation rates in active NIH-funded CTs.

IC Name
NATIONAL INSTITUTE ON AGING
  • Activity
    R24
  • Administering IC
    AG
  • Application Type
    1
  • Direct Cost Amount
    499220
  • Indirect Cost Amount
    262091
  • Total Cost
    761311
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    866
  • Ed Inst. Type
    SCHOOLS OF ARTS AND SCIENCES
  • Funding ICs
    NIA:761311\
  • Funding Mechanism
    OTHER RESEARCH-RELATED
  • Study Section
    ZAG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    UNIVERSITY OF FLORIDA
  • Organization Department
    MISCELLANEOUS
  • Organization DUNS
    969663814
  • Organization City
    GAINESVILLE
  • Organization State
    FL
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    326115500
  • Organization District
    UNITED STATES