Information
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Patent Application
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20070225312
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Publication Number
20070225312
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Date Filed
March 21, 200717 years ago
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Date Published
September 27, 200716 years ago
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Inventors
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Original Assignees
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CPC
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US Classifications
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International Classifications
Abstract
The present invention relates to the use of terguride and proterguride for the prophylaxis and/or the treatment of chronic pain conditions as well as to pharmaceutical compositions comprising terguride and/or proterguride optionally together with an opiate analgesic.
Claims
- 1. Use of terguride or proterguride or a combination of terguride and proterguride or pharmacologically acceptable salts thereof for the preparation of a drug for the prophylaxis and/or the treatment of chronic pain or chronic pain conditions.
- 2. Use according to claim 1 for the treatment of persistent musculoskeletal pains and persistent visceral pains.
- 3. Use according to claim 2 for the treatment of persistent back pains, persistent neck pains, persistent shoulder pains, persistent joint pains and fibromyalgia.
- 4. Use according to claim 2 for the prophylaxis and the treatment of pains associated with premenstrual syndrome, mastalgia, stomach pain associated with irritable colon and pains associated with carcinoid syndrome.
- 5. Use according to claim 1 for the prophylaxis and the treatment of head pains and migraine.
- 6. Use according to claim 1 for the treatment of neuralgias, trigeminal neuralgia, postherpetic neuralgia, neuropathic pains and tumor associated pains.
- 7. Use according to claim 1 in combination with an opiate analgesic, dihydrocodeine, tramadol, morphine, morphine sulfate, oxycodone, methadone, hydromorphone, buprenorphine and fentanyl.
- 8. Pharmaceutical composition comprising terguride or proterguride or a combination of terguride and proterguride or their pharmacologically acceptable salts together with at least one pharmacologically acceptable carrier, auxiliary agent or solvent.
- 9. Pharmaceutical composition according to claim 8 suitable for inhalation or for intravenous, intraperitoneal, intramuscular, intravaginal, intrabuccal, percutaneous, subcutaneous, mucocutaneous, oral, peroral lumbar, rectal, transdermal, topical, intradermal, intragastric or intracutaneous administration.
- 10. Pharmaceutical composition according to claim 8 further comprising an active agent selected from the group comprising opiate analgesic, dihydrocodeine, tramadol, morphine, morphine sulfate, oxycodone, methadone, hydromorphone, buprenorphine and fentanyl.
- 11. Pharmaceutical composition according to claim 8 comprising terguride in the dose range of 0.1-3.0 mg per pharmaceutical formulation and/or proterguride in the dose range of 0.002-0.5 mg per pharmaceutical formulation.
- 12. Use according to claim 2 in combination with an opiate analgesic, dihydrocodeine, tramadol, morphine, morphine sulfate, oxycodone, methadone, hydromorphone, buprenorphine and fentanyl.
- 13. Use according to claim 3 in combination with an opiate analgesic, dihydrocodeine, tramadol, morphine, morphine sulfate, oxycodone, methadone, hydromorphone, buprenorphine and fentanyl.
- 14. Use according to claim 4 in combination with an opiate analgesic, dihydrocodeine, tramadol, morphine, morphine sulfate, oxycodone, methadone, hydromorphone, buprenorphine and fentanyl.
- 15. Use according to claim 5 in combination with an opiate analgesic, dihydrocodeine, tramadol, morphine, morphine sulfate, oxycodone, methadone, hydromorphone, buprenorphine and fentanyl.
- 16. Use according to claim 6 in combination with an opiate analgesic, dihydrocodeine, tramadol, morphine, morphine sulfate, oxycodone, methadone, hydromorphone, buprenorphine and fentanyl.
- 17. Pharmaceutical composition according to claim 9 further comprising an active agent selected from the group comprising opiate analgesic, dihydrocodeine, tramadol, morphine, morphine sulfate, oxycodone, methadone, hydromorphone, buprenorphine and fentanyl.
- 18. Pharmaceutical composition according to claim 9 comprising terguride in the dose range of 0.1-3.0 mg per pharmaceutical formulation and/or proterguride in the dose range of 0.002-0.5 mg per pharmaceutical formulation.
- 19. Pharmaceutical composition according to claim 10 comprising terguride in the dose range of 0.1-3.0 mg per pharmaceutical formulation and/or proterguride in the dose range of 0.002-0.5 mg per pharmaceutical formulation.
- 20. Pharmaceutical composition according to claim 17 comprising terguride in the dose range of 0.1-3.0 mg per pharmaceutical formulation and/or proterguride in the dose range of 0.002-0.5 mg per pharmaceutical formulation.
Priority Claims (1)
Number |
Date |
Country |
Kind |
10 2006 013 307.2 |
Mar 2006 |
DE |
national |