The Generation and Analysis of Genetic DNA Sequence Information in the Undergraduate Curriculum

Information

  • NSF Award
  • 9650105
Owner
  • Award Id
    9650105
  • Award Effective Date
    7/1/1996 - 28 years ago
  • Award Expiration Date
    6/30/1998 - 26 years ago
  • Award Amount
    $ 25,750.00
  • Award Instrument
    Standard Grant

The Generation and Analysis of Genetic DNA Sequence Information in the Undergraduate Curriculum

This project concerns the acquisition of a safe, reliable, and cost-effective DNA sequencing instrument that can be used in undergraduate education and research. The evolving biotechnology curriculum in the Department of Biological Sciences has three components: recombinant DNA techniques, the generation of genetic sequence information, and the analysis and manipulation of genetic information. The project focuses on meeting the instrumentation needs of the second component by obtaining a fluorescent-based DNA sequencer that uses a new capillary matrix electrophoresis technology. This instrument meets all of the project's requirements in being safe (no radioactive nucleotides and no acrylamide gels), reliable (fluorescent nucleotide chemistry is a standard technology in the genome projects), and cost-effective (DNA sequencing reactions are performed using a polymerase chain reaction sequencing kit at a cost of about $5 per reaction). All biology undergraduate students can learn how biotechnology is performed by gaining hands-on experience in structured required laboratory class exercises and in doing independent, faculty-sponsored research projects. For students to prepare for the careers of the future and for their taking on leadership roles after graduation, it is imperative that undergraduate students majoring in biology have a firm understanding of what biotechnology is and how this discipline is affecting science and society.

  • Program Officer
    Terry S. Woodin
  • Min Amd Letter Date
    4/2/1996 - 28 years ago
  • Max Amd Letter Date
    4/2/1996 - 28 years ago
  • ARRA Amount

Institutions

  • Name
    University of the Sciences in Philadelphia
  • City
    Philadelphia
  • State
    PA
  • Country
    United States
  • Address
    600 South 43rd Street
  • Postal Code
    191044418
  • Phone Number
    2155967491

Investigators

  • First Name
    John
  • Last Name
    Porter
  • Email Address
    j.porter@usp.edu
  • Start Date
    4/2/1996 12:00:00 AM
  • First Name
    James
  • Last Name
    Pierce
  • Email Address
    j.pierce@usip.edu
  • Start Date
    4/2/1996 12:00:00 AM
  • First Name
    James
  • Last Name
    Johnson
  • Email Address
    johnson@shrsys.hslc.org
  • Start Date
    4/2/1996 12:00:00 AM
  • First Name
    Ara
  • Last Name
    DerMarderosian
  • Email Address
    arad@shrsys.hslc.org
  • Start Date
    4/2/1996 12:00:00 AM

FOA Information

  • Name
    Other Applications NEC
  • Code
    99
  • Name
    Life Science Biological
  • Code
    61

Program Element

  • Text
    UNDERGRAD INSTRM & LAB IMPROVE
  • Code
    7400

Program Reference

  • Text
    UNDERGRADUATE EDUCATION
  • Code
    9178
  • Text
    INSTRUMENTATION & LAB IMPROVE.
  • Code
    9267
  • Text
    SCIENCE, MATH, ENG & TECH EDUCATION