Claims
- 1. A thiazolylphthalide compound of the formula ##STR32## wherein A represents a p-aminophenyl radical of formula ##STR33## each of R.sub.1, R.sub.2, X.sub.1 and X.sub.2, independently represents hydrogen, alkyl of 1 to 12 carbon atoms, alkoxyalkyl of 2 to 8 carbon atoms, benzyl or phenyl, or
- each pair of substituents R.sub.1 and R.sub.2, X.sub.1 and X.sub.2, together with the nitrogen atom to which they are attached, independently represent a pyrrolidine, piperidine or morpholine,
- Y represents hydrogen, alkyl of 1 to 12 carbon atoms, benzyl or phenyl or phenyl substituted by halogen, nitro, alkyl, alkoxy or dialkylamino, each containing 1 to 4 carbon atoms in the alkyl moiety,
- V represents hydrogen, alkyl of 1 to 12 carbon atoms, alkoxy of 1 to 12 carbon atoms or alkanoyloxy of 2 to 4 carbon atoms, and
- the benzene rings B is unsubstituted or substituted by halogen, nitro or by an amino group which is unsubstituted or substituted by alkyl of 1 to 6 carbon atoms, and
- wherein at least one pair of substituents R.sub.1 and R.sub.2, X.sub.1 and X.sub.2, together with the nitrogen atom to which they are attached represent a pyrrolidine, piperidine or morpholine.
- 2. The thiazolylphthalide compound of claim 1, wherein each of R.sub.1, R.sub.2, X.sub.1 and X.sub.2, independently represents hydrogen, alkyl of 1 to 12 carbon atoms, phenyl or benzyl, or
- each pair of substituents R.sub.1 and R.sub.2, X.sub.1 and X.sub.2, together with the nitrogen atoms to which they are attached, independently represent a pyrrolidine, piperidine or morpholine,
- Y represents hydrogen, alkyl of 1 to 4 carbon atoms, phenyl or phenyl substituted by halogen, nitro, alkyl, alkoxy or dialkylamino, each containing 1 to 4 carbon atoms in the alkyl moiety,
- V represents hydrogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms or alkanoyloxy of 2 to 4 carbon atoms, and
- the benzene rings B is unsubstituted or substituted by halogen, nitro or dialkylamino containing 1 to 4 carbon atoms in each alkyl moiety and whereby at least one pair of the substituents R.sub.1 and R.sub.2, X.sub.1 and X.sub.2, together with the nitrogen atom to which they are attached represent a pyrrolidine, piperidine or morpholine.
- 3. The thiazolylphthalide compound of claim 1 of the formula ##STR34## wherein each of R.sub.1 and R.sub.2 independently represents alkyl of 1 to 8 carbon atoms, phenyl or benzyl,
- X.sub.1 and X.sub.2, together with the nitrogen atom to which they are attached, represent a pyrrolidine, piperidine or morpholine,
- Y represents methyl or phenyl, V represents hydrogen, methyl, alkoxy of 1 to 4 carbon atoms or alkanoyloxy of 2 to 4 carbon atoms, and
- wherein the benzene ring B is unsubstituted or substituted by 1 to 4 chlorine atoms or a nitro group.
- 4. The thiazolylphthalide compound of claim 1 of the formula ##STR35## wherein X.sub.1 represents alkyl of 1 to 8 carbon atoms, phenyl or benzyl, X.sub.2 represents hydrogen, alkyl of 1 to 4 carbon atoms or benzyl, and
- R.sub.1 and R.sub.2, together with the nitrogen atom to which they are attached, represent a pyrrolidine, piperidine or morpholine,
- Y represents methyl or phenyl, V represents hydrogen, methyl, alkoxy of 1 to 4 carbon atoms or alkanoyloxy of 2 to 4 carbon atoms, and
- wherein the benzene ring B is unsubstituted or substituted by 1 to 4 chlorine atoms or a nitro group.
- 5. The thiazolylphthalide compound of claim 3 wherein R.sub.1 and R.sub.2 independently are alkyl of 1 to 4 carbon atoms or benzyl,
- V is hydrogen or ethoxy and
- X.sub.1 and X.sub.2 together with the nitrogen atom to which they are attached represents pyrrolidinyl and wherein the benzene ring B is unsubstituted.
Priority Claims (1)
Number |
Date |
Country |
Kind |
15189/74 |
Nov 1974 |
CHX |
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Parent Case Info
This is a division of application Ser. No. 629,156 filed on Nov. 5, 1975; now U.S. Pat. No. 4,100,169.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4086239 |
Fancher |
Apr 1978 |
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Divisions (1)
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Number |
Date |
Country |
Parent |
629156 |
Nov 1975 |
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