Claims
- 1. A compound of the formula ##STR31## wherein R.sup.1 and R.sup.2 independently represent hydrogen, C.sub.1-4 alkyl, halogen, C.sub.1-4 haloalkyl, nitro, amino, C.sub.1-4 alkoxy, C.sub.1-4 alkylthio or a group of the formula --SO.sub.2 N(R.sup.4).sub.2 where R.sup.4 is C.sub.1-4 alkyl; Q represents hydroxyl, thiol, halogen, --NH.sub.2, mono--C.sub.1-4 --alkyl--amino, or di--C.sub.1-4 alkylamino; and the thiophene ring is unsubstituted or is substituted by a C.sub.1-4 alkyl in the 2-position.
- 2. The compound of claim 1 which is of the formula ##STR32##
- 3. A compound of claim 2 which is 9,10-dihydro-2-ethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 4. The compound of claim 2 which is 2-ethyl-7-fluoro-9,10-dihydro-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 5. The compound of claim 2 which is 6,8-difluoro-9,10-dihydro-2-ethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 6. The compound of claim 2 which is 9,10-dihydro-2-ethyl-6-fluoro-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 7. The compound of claim 2 which is 7-chloro-9,10-dihydro-2-ethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 8. The compound of claim 2 which is 7-amino-9,10-dihydro-2-ethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 9. The compound of claim 2 which is 9,10-dihydro-2-ethyl-6-methyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 10. The compound of claim 2 which is 9,10-dihydro-7-N,N-dimethylsulphonamido-2-ethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 11. The compound of claim 2 which is 9,10-dihydro-2-ethyl-7-nitro-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 12. The compound of claim 2 which is 9,10-dihydro-7-fluoro-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 13. The compound of claim 2 which is 9,10-dihydro-2-ethyl-7-trifluoromethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 14. The compound of claim 2 which is 9,10-dihydro-2-ethyl-7-methoxy-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 15. The compound of claim 2 which is 9,10-dihydro-2-ethyl-7-methylthio-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 16. The compound of claim 2 which is 6,7-difluoro-9,10-dihydro-2-ethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 17. The compound of claim 2 which is 9,10-dihydro-7-fluoro-2-methyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 18. The compound of claim 2 which is 2-i-propyl-7-fluoro-9,10-dihydro-4H-thieno[2,3-b][1,5]benzodiazepin-10-one
- 19. The compound of claim 2 which is 9,10-dihydro-2-ethyl-6-trifluoromethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 20. The compound of claim 2 which is 7-acetamido-9,10-dihydro-2-ethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-one.
- 21. The compound of claim 1 which is of the formula ##STR33##
- 22. The compound of claim 21 which is 9,10-dihydro-2-ethyl-7-fluoro-4H-thieno[2,3-b][1,5]benzodiazepin-10-thione.
- 23. The compound of claim 21 which is 9,10-dihydro-2-ethyl-4H-thieno[2,3-b][1,5]benzodiazepin-10-thione.
- 24. The compound of claim 21 which is 9,10-dihydro-2-ethyl-7-nitro-4H-thieno[2,3-b][1,5]benzodiazepin-10-thione.
Priority Claims (1)
Number |
Date |
Country |
Kind |
51240/74 |
Nov 1974 |
GBX |
|
Parent Case Info
This is a division, of application Ser. No. 633,895, filed Nov. 20, 1975 now abandoned.
US Referenced Citations (4)
Non-Patent Literature Citations (2)
Entry |
Burger "Medicinal Chemistry" 2nd Ed. pp. 72-81, (Interscience) (1960). |
Hromatka et al., "Monatshefte fur Chemie," Band 106, Heft 2 (Mar.-Apr. 1975), pp. 375-379. |
Divisions (1)
|
Number |
Date |
Country |
Parent |
633895 |
Nov 1975 |
|