Three dimensional coordinates of melanin-concentrating hormone receptors

Abstract

Three-dimensional coordinates of melanin-concentrating hormone receptors are useful in computer aided drug design.

Description

FIELD OF THE INVENTION

The present invention relates to three-dimensional structures of G protein-coupled receptors, especially melanin-concentrating hormone receptor 1, and structures derived therefrom.

BACKGROUND OF THE INVENTION

I. GPCRs

Most eukaryotic organisms utilize guanine nucleotide-binding regulatory protein (hereinafter, referred to as “G protein”)-coupled receptors (G protein-coupled receptors; hereinafter, frequently referred to as “GPCRs”) to respond to a variety of stimuli such as Ca²⁺, amines, hormones, peptides, and even large proteins. Each GPCR is composed of an extracellular region, an intracellular region and a transmembrane bundle of seven α-helices. The binding of specific ligands to the extracellular or transmembrane domain evokes conformational changes that are transmitted to the intracellular region. The conformational switch from inactive to active state in the intracellular region produces a catalytically competent receptor that is responsible for binding and nucleotide exchange (GDPGTP) on the α-subunit of several hundreds of G proteins of a specific subtype. The α-and/or A′-subunit of the G proteins activates the next target protein(s) to evoke further intracellular responses. Because all of several hundreds of members in the GPCR family appear to share a common motif in their transmembrane structure and a common topology, it is generally accepted that a similar switching mechanism functions in all of these receptors.

II. MCH-R1

Neuropeptides present in the hypothalamus play a major role in mediating the control of body weight. (Flier, et al. 1998. Cell, 92, 437-440). Melanin-concentrating hormone (MCH) produced in mammals is a cyclic 19-amino acid neuropeptide synthesized as part of a larger pre-prohormone precursor in the hypothalamus which also encodes neuropeptide EI (NEI) and neuropeptide GE (NGE). (Nahon, et al., 1990. Mol. Endocrinol. 4,632-637; Vaughan, et al., U.S. Pat. No 5,049,655; and Vaughan, et al., 1989. Endocrinology 125, 1660-1665.) MCH was first identified in salmon pituitary. In fish, MCH affects melanin aggregation thus affecting skin pigmentation. In trout and eels MCH has also been shown to be involved in stress induced or corticotropin-releasing-factor (CRF)-stimulated adrenocorticotropin (ACTH) release. (Kawauchi, et al., 1983. Nature 305, 321-323.)

In humans two genes encoding MCH have been identified that are expressed in the brain. (Breton, et al., 1993. Mol. Brain Res. 18, 297-310.) In mammals MCH has been localized primarily to neuronal cell bodies of the hypothalamus which are implicated in the control of food intake, including perikarya of the lateral hypothalamus and zona inertia. (Knigge, et al., 1996. Peptides 17, 1063-1073.)

Pharmacological and genetic evidence suggest that the primary mode of MCH action is to promote feeding (orexigenic). MCH mRNA is up-regulated in fasted mice and rats, in the ob/ob mouse and in mice with targeted disruption in the gene for neuropeptide Y (NPY). (Qu, et al., 1996. Nature 380, 243-247 and Erickson, et al., 1996. Nature 381, 415-418.) Injection of MCH centrally (ICV) stimulates food intake and MCH antagonizes the hypophagic effects seen with the α melanocyte stimulating hormone (αMSH). (Qu, et al., 1996. Nature 380, 243-247.) MCH deficient mice are lean, hypophagic and have increased metabolic rate. (Shimada, et al., 1998. Nature 396, 670-673.) The administration of MCH has been indicated to be useful for promoting eating, appetite or the gain or maintenance of weight. (Maratos-Flier, U.S. Pat. No. 5,849,708.)

MCH action is not limited to modulation of food intake as effects on the hypothalamic-pituitary-axis have been reported. (Nahon, 1994. Critical Rev. in Neurobiol. 8, 221-262.) MCH may be involved in the body response to stress as MCH can modulate the stress-induced release of CRF from the hypothalamus and ACTH from the pituitary. In addition, MCH neuronal systems may be involved in reproductive or maternal function.

MCH can bind at least two different receptors: MCH-R1 and MCH-R2. (Chambers, et al. 1999. Nature 400, 262-265; Saito, et al., 1999. Nature 400, 265-269; Bäichner, et al., 1999. FEBS Letters 457:522-524; Shimomura, et al., 1999. Biochemical and Biophysical Research Communications 261, 622-626; Sailer, et al., Proc. Natl. Acad. Sci. 98:7564-7569, 2001.) The amino acid identity between MCH-R2 and MCH-R1 is about 38%. (Sailer, et al., Proc. Natl. Acad. Sci. 98:7564-7569, 2001). MCH-R2 is detected specifically in most regions of the brain, with an expression pattern similar to that of MCH-R1.

Because MCH is an important regulator of food intake and energy balance, agents capable of modulating MCH receptor activity, especially MCH-R1, are highly desirable for the treatment of obesity, eating disorders (e.g., bulimia and anorexia), sexual disorders (e.g., anorgasmic or psychogenic impotence) and metabolic disorders, such as diabetes. Small molecule, non-peptide antagonists of MCH receptors would be of particular value as therapeutic agents for the diagnosis, treatment or prevention of diseases and disorders mediated through the MCH receptor, more particularly eating disorders related to obesity of any cause in humans. Thus there is a need to provide for potent and selective antagonists of the MCH-R1 receptor.

III. Three-Dimensional Structural Information

The biological properties of a protein depend directly on the protein's three-dimensional (3D) conformation. In turn, the 3D conformation determines the activity of enzymes, the capacity and specificity of binding proteins, and the potential for small molecules to interact with the receptor. Models at the atomic level are needed to obtain insight into the mechanisms of MCH-R1 activation, and the source of interactions between specific ligands and MCH-R1. Thus, there is a need for 3D structure models for the MCH-R1 receptor.

SUMMARY OF THE INVENTION

The present invention attempts to address this need by providing a 3D structure of human MCH-R1 receptor that is useful in identifying potent and selective agonists or antagonist of the MCH-R1 receptor for the treatment of MCH-R1 mediated disorders.

One aspect of the invention provides for a method of identifying a drug candidate useful for the treatment of a melanin concentrating hormone receptor 1 (MCH-R1) mediated disorder comprising the steps of:

• • (a) using a three-dimensional (3D) structure of MCH-R1 according to Table 1;
  • (b) employing said 3D structure to design or select in silico said drug candidate.

Another aspect of the invention provides a G-protein-coupled receptor selected from the group consisting of the following (a) or (b):

• • (a) a G protein-coupled receptor having three-dimensional structure I defined by the atomic coordinates as shown in Table 1;
  • (b) a G protein-coupled receptor having three-dimensional structure II defined by derived coordinates from the atomic coordinates as shown in Table 1, wherein the mean residual of the discrepancies between the positions of the α carbon atoms in the amino acid residues of seven helix sites SEQ ID NOS: 2-8 of the three-dimensional structure I and the positions of the corresponding α carbon atoms in the amino acid residues of the corresponding seven helix sites of the three-dimensional structure II is 1.5 Å or less when an image of the three-dimensional structure I obtained by computer-processing the atomic coordinates of Table 1 and an image of the three-dimensional structure II obtained by computer-processing said derived coordinates are superimposed.

These and other objects, features, and advantages will become apparent to those of ordinary skill in the art from a reading of the following detailed description and the appended claims.

SEQUENCE LISTING DESCRIPTION

Each of the protein sequences in the sequence listing is shown in Table A.

TABLE A
		Position on SEQ ID
Sequence Description	SEQ ID NO:	NO:1
MCH-R1a	1	—
HI	2	106-135
HII	3	146-175
HIII	4	183-213
HIV	5	226-249
HV	6	274-302
HVI	7	319-350
HVII	8	360-383
ECI	9	176-182
ECII	10	250-273
ECIII	11	351-359
ICI	12	136-145
IC2	13	214-225
IC3	14	303-318
CTERM	15	384-401
THI	16	106-120
THII-ECI-THIII	17	161-197
THIV-ECII-THV	18	235-288
THVI-ECIII-THVII	19	336-374
THII	20	161-175
THIII	21	183-197
THIV	22	235-249
THV	23	274-288
THVI	24	336-350
THVII	25	360-374
aThe corresponding human MCH-R1 accession number is NP_005288

DETAILED DESCRIPTION OF THE INVENTION

I. 3D Coordinates of MCH-R1

G protein-coupled receptors (GPCRs) function in a number of signaling pathways, converting a variety of external stimuli to activate multiple copies of G protein subtypes specific to the relevant G protein-coupled receptor. GPCRs, including MCH-R1, share many structural features, including a bundle of seven transmembrane α-helices connected by six loops of varying lengths. In the present invention, in silico 3D coordinates of the transmembrane intra- and extra-cellular regions of MCH-R1 are provided. These coordinates were obtained by homology from the 3D structure of bacterial rhodopsin and in-house SAR data. The model was later refined using the 3D coordinates of mammalian rhodopsin (Palczewski, K.; Kumasaka, T.; Hori, T.; Behnke, C. A.; Motoshima, H.; Fox, B. A.; Trong, I. L.; Teller, D. C.; Okada, T.; Stenkamp, R. E.; Yamamoto, M.; Miyano, M. Science, 2000, 289, 739). Further refinement, such as coordinates modification in view of SAR data generated in-house, was also performed.

As a result of the above analysis, the 3D structure of human MCH-R1 receptor can be obtained as 3D coordinates. The atomic coordinates obtained by the invention are shown in Table 1 below.

TABLE 1
ATOM	1	N	ILE	105	−40.873	24.697	19.527
ATOM	2	CA	ILE	105	−40.26	23.523	20.146
ATOM	3	C	ILE	105	−41.295	22.42	20.21
ATOM	4	O	ILE	105	−41.087	21.377	19.609
ATOM	5	CB	ILE	105	−39.654	23.854	21.544
ATOM	6	CG1	ILE	105	−38.606	25.001	21.407
ATOM	7	CG2	ILE	105	−39.038	22.574	22.18
ATOM	8	CD1	ILE	105	−38.033	25.492	22.765
ATOM	9	HA	ILE	105	−39.43	23.17	19.508
ATOM	10	HB	ILE	105	−40.46	24.211	22.205
ATOM	11	HG11	ILE	105	−37.774	24.675	20.762
ATOM	12	HG12	ILE	105	−39.086	25.868	20.924
ATOM	13	HD11	ILE	105	−37.396	24.728	23.234
ATOM	14	HD12	ILE	105	−37.415	26.39	22.607
ATOM	15	HD13	ILE	105	−38.849	25.751	23.457
ATOM	16	HG21	ILE	105	−38.179	22.226	21.586
ATOM	17	HG22	ILE	105	−39.779	21.762	22.227
ATOM	18	HG23	ILE	105	−38.702	22.763	23.21
ATOM	19	H	ILE	105	−41.501	25.27	20.055
ATOM	20	HNCA	ILE	105	−40.694	24.898	18.563
ATOM	21	N	SER	106	−42.427	22.608	20.925
ATOM	22	CA	SER	106	−43.437	21.553	20.948
ATOM	23	C	SER	106	−43.939	21.352	19.539
ATOM	24	O	SER	106	−43.916	20.23	19.06
ATOM	25	CB	SER	106	−44.63	21.864	21.888
ATOM	26	OG	SER	106	−45.569	20.776	21.819
ATOM	27	HA	SER	106	−42.972	20.617	21.304
ATOM	28	H	SER	106	−42.608	23.462	21.415
ATOM	29	HB1	SER	106	−44.256	21.98	22.919
ATOM	30	HB2	SER	106	−45.118	22.804	21.582
ATOM	31	HG	SER	106	−46.329	20.901	22.38
ATOM	32	N	TYR	107	−44.382	22.423	18.842
ATOM	33	CA	TYR	107	−44.881	22.238	17.481
ATOM	34	C	TYR	107	−43.857	21.508	16.64
ATOM	35	O	TYR	107	−44.239	20.669	15.84
ATOM	36	CB	TYR	107	−45.305	23.562	16.79
ATOM	37	CG	TYR	107	−44.099	24.423	16.387
ATOM	38	CD1	TYR	107	−43.604	25.416	17.24
ATOM	39	CD2	TYR	107	−43.491	24.23	15.142
ATOM	40	CE1	TYR	107	−42.53	26.22	16.845
ATOM	41	CE2	TYR	107	−42.435	25.05	14.735
ATOM	42	CZ	TYR	107	−41.941	26.042	15.587
ATOM	43	OH	TYR	107	−40.867	26.831	15.165
ATOM	44	HA	TYR	107	−45.781	21.608	17.559
ATOM	45	H	TYR	107	−44.381	23.338	19.244
ATOM	46	HB2	TYR	107	−45.878	23.323	15.878
ATOM	47	HB1	TYR	107	−45.976	24.13	17.453
ATOM	48	HD2	TYR	107	−43.836	23.441	14.481
ATOM	49	HE2	TYR	107	−41.992	24.918	13.754
ATOM	50	HE1	TYR	107	−42.161	26.982	17.523
ATOM	51	HD1	TYR	107	−44.052	25.575	18.215
ATOM	52	HH	TYR	107	−40.605	27.502	15.785
ATOM	53	N	ILE	108	−42.545	21.786	16.815
ATOM	54	CA	ILE	108	−41.542	21.036	16.059
ATOM	55	C	ILE	108	−41.648	19.586	16.482
ATOM	56	O	ILE	108	−41.731	18.716	15.627
ATOM	57	CB	ILE	108	−40.087	21.572	16.255
ATOM	58	CG1	ILE	108	−39.975	23.043	15.75
ATOM	59	CG2	ILE	108	−39.064	20.648	15.534
ATOM	60	CD1	ILE	108	−38.596	23.707	16.008
ATOM	61	HA	ILE	108	−41.785	21.104	14.986
ATOM	62	H	ILE	108	−42.252	22.445	17.508
ATOM	63	HB	ILE	108	−39.853	21.552	17.332
ATOM	64	HG11	ILE	108	−40.201	23.087	14.673
ATOM	65	HG12	ILE	108	−40.716	23.659	16.277
ATOM	66	HD11	ILE	108	−37.811	23.271	15.373
ATOM	67	HD12	ILE	108	−38.652	24.783	15.776
ATOM	68	HD13	ILE	108	−38.305	23.596	17.064
ATOM	69	HG21	ILE	108	−39.24	20.655	14.447
ATOM	70	HG22	ILE	108	−38.029	20.962	15.728
ATOM	71	HG23	ILE	108	−39.153	19.614	15.895
ATOM	72	N	ASN	109	−41.653	19.299	17.803
ATOM	73	CA	ASN	109	−41.743	17.907	18.244
ATOM	74	C	ASN	109	−43.096	17.296	17.937
ATOM	75	O	ASN	109	−43.193	16.085	18.026
ATOM	76	CB	ASN	109	−41.43	17.759	19.758
ATOM	77	CG	ASN	109	−41.147	16.333	20.179
ATOM	78	OD1	ASN	109	−40.861	15.493	19.341
ATOM	79	ND2	ASN	109	−41.198	16.019	21.49
ATOM	80	HA	ASN	109	−40.981	17.34	17.682
ATOM	81	H	ASN	109	−41.622	20.028	18.493
ATOM	82	HB1	ASN	109	−40.527	18.343	19.995
ATOM	83	HB2	ASN	109	−42.272	18.172	20.334
ATOM	84	HD22	ASN	109	−41.006	15.078	21.773
ATOM	85	HD21	ASN	109	−41.418	16.704	22.185
ATOM	86	N	ILE	110	−44.152	18.061	17.577
ATOM	87	CA	ILE	110	−45.382	17.447	17.06
ATOM	88	C	ILE	110	−45.199	17.126	15.588
ATOM	89	O	ILE	110	−45.728	16.121	15.139
ATOM	90	CB	ILE	110	−46.627	18.364	17.283
ATOM	91	CG1	ILE	110	−46.893	18.527	18.813
ATOM	92	CG2	ILE	110	−47.882	17.806	16.548
ATOM	93	CD1	ILE	110	−47.977	19.581	19.17
ATOM	94	HA	ILE	110	−45.583	16.499	17.586
ATOM	95	H	ILE	110	−44.09	19.059	17.601
ATOM	96	HB	ILE	110	−46.407	19.348	16.842
ATOM	97	HG11	ILE	110	−47.188	17.555	19.243
ATOM	98	HG12	ILE	110	−45.963	18.836	19.312
ATOM	99	HD11	ILE	110	−48.982	19.247	18.876
ATOM	100	HD12	ILE	110	−47.989	19.748	20.259
ATOM	101	HD13	ILE	110	−47.763	20.541	18.678
ATOM	102	HG21	ILE	110	−48.131	16.803	16.926
ATOM	103	HG22	ILE	110	−48.753	18.461	16.688
ATOM	104	HG23	ILE	110	−47.712	17.739	15.463
ATOM	105	N	ILE	111	−44.47	17.941	14.793
ATOM	106	CA	ILE	111	−44.342	17.631	13.365
ATOM	107	C	ILE	111	−43.666	16.288	13.173
ATOM	108	O	ILE	111	−44.235	15.43	12.517
ATOM	109	CB	ILE	111	−43.61	18.762	12.571
ATOM	110	CG1	ILE	111	−44.517	20.032	12.49
ATOM	111	CG2	ILE	111	−43.205	18.277	11.148
ATOM	112	CD1	ILE	111	−43.768	21.317	12.041
ATOM	113	HA	ILE	111	−45.357	17.545	12.942
ATOM	114	H	ILE	111	−44.02	18.758	15.161
ATOM	115	HB	ILE	111	−42.683	19.014	13.113
ATOM	116	HG11	ILE	111	−45.355	19.844	11.799
ATOM	117	HG12	ILE	111	−44.953	20.241	13.478
ATOM	118	HD11	ILE	111	−43.425	21.248	10.999
ATOM	119	HD12	ILE	111	−44.443	22.184	12.113
ATOM	120	HD13	ILE	111	−42.898	21.502	12.688
ATOM	121	HG21	ILE	111	−44.1	17.975	10.583
ATOM	122	HG22	ILE	111	−42.688	19.067	10.586
ATOM	123	HG23	ILE	111	−42.515	17.421	11.196
ATOM	124	N	MET	112	−42.442	16.068	13.704
ATOM	125	CA	MET	112	−41.75	14.813	13.397
ATOM	126	C	MET	112	−42.571	13.561	13.668
ATOM	127	O	MET	112	−42.664	12.764	12.748
ATOM	128	CB	MET	112	−40.332	14.694	14.022
ATOM	129	CG	MET	112	−39.649	13.368	13.585
ATOM	130	SD	MET	112	−37.912	13.33	14.13
ATOM	131	CE	MET	112	−37.437	11.674	13.55
ATOM	132	HA	MET	112	−41.582	14.852	12.307
ATOM	133	H	MET	112	−41.982	16.768	14.257
ATOM	134	HB1	MET	112	−39.719	15.544	13.68
ATOM	135	HB2	MET	112	−40.388	14.739	15.12
ATOM	136	HG1	MET	112	−40.169	12.502	14.025
ATOM	137	HG2	MET	112	−39.66	13.27	12.488
ATOM	138	LPD1	MET	112	−37.544	13.817	13.833
ATOM	139	LPD2	MET	112	−37.859	13.386	14.805
ATOM	140	HE1	MET	112	−37.553	11.606	12.459
ATOM	141	HE2	MET	112	−36.388	11.483	13.818
ATOM	142	HE3	MET	112	−38.079	10.928	14.04
ATOM	143	N	PRO	113	−43.183	13.276	14.845
ATOM	144	CA	PRO	113	−43.927	12.033	14.98
ATOM	145	C	PRO	113	−45.09	11.98	14.016
ATOM	146	O	PRO	113	−45.422	10.888	13.582
ATOM	147	CB	PRO	113	−44.354	12.093	16.467
ATOM	148	CG	PRO	113	−44.337	13.597	16.812
ATOM	149	CD	PRO	113	−43.135	14.149	16.005
ATOM	150	HA	PRO	113	−43.263	11.171	14.809
ATOM	151	HD2	PRO	113	−42.198	13.995	16.561
ATOM	152	HD1	PRO	113	−43.273	15.21	15.772
ATOM	153	HG2	PRO	113	−44.26	13.778	17.896
ATOM	154	HG1	PRO	113	−45.278	14.043	16.453
ATOM	155	HB1	PRO	113	−45.336	11.633	16.649
ATOM	156	HB2	PRO	113	−43.6	11.585	17.093
ATOM	157	N	SER	114	−45.72	13.116	13.637
ATOM	158	CA	SER	114	−46.755	13.049	12.606
ATOM	159	C	SER	114	−46.127	12.61	11.301
ATOM	160	O	SER	114	−46.705	11.792	10.602
ATOM	161	CB	SER	114	−47.46	14.416	12.407
ATOM	162	OG	SER	114	−48.039	14.818	13.661
ATOM	163	HA	SER	114	−47.521	12.316	12.912
ATOM	164	H	SER	114	−45.459	14.016	13.997
ATOM	165	HB1	SER	114	−46.731	15.168	12.064
ATOM	166	HB2	SER	114	−48.246	14.316	11.638
ATOM	167	HG	SER	114	−48.47	15.666	13.617
ATOM	168	N	VAL	115	−44.929	13.139	10.957
ATOM	169	CA	VAL	115	−44.262	12.684	9.738
ATOM	170	C	VAL	115	−43.977	11.207	9.882
ATOM	171	O	VAL	115	−44.283	10.459	8.967
ATOM	172	CB	VAL	115	−42.952	13.471	9.427
ATOM	173	CG1	VAL	115	−42.158	12.814	8.263
ATOM	174	CG2	VAL	115	−43.268	14.953	9.078
ATOM	175	HA	VAL	115	−44.95	12.823	8.888
ATOM	176	H	VAL	115	−44.467	13.802	11.552
ATOM	177	HB	VAL	115	−42.303	13.451	10.317
ATOM	178	HG11	VAL	115	−42.787	12.736	7.362
ATOM	179	HG12	VAL	115	−41.266	13.411	8.018
ATOM	180	HG13	VAL	115	−41.82	11.806	8.544
ATOM	181	HG21	VAL	115	−43.842	15.437	9.88
ATOM	182	HG22	VAL	115	−42.335	15.521	8.936
ATOM	183	HG23	VAL	115	−43.857	15.011	8.15
ATOM	184	N	PHE	116	−43.398	10.749	11.015
ATOM	185	CA	PHE	116	−43.148	9.317	11.156
ATOM	186	C	PHE	116	−44.44	8.553	10.983
ATOM	187	O	PHE	116	−44.444	7.548	10.291
ATOM	188	CB	PHE	116	−42.541	8.909	12.522
ATOM	189	CG	PHE	116	−42.41	7.379	12.547
ATOM	190	CD1	PHE	116	−41.398	6.758	11.807
ATOM	191	CD2	PHE	116	−43.308	6.591	13.278
ATOM	192	CE1	PHE	116	−41.344	5.365	11.716
ATOM	193	CE2	PHE	116	−43.24	5.196	13.208
ATOM	194	CZ	PHE	116	−42.281	4.584	12.396
ATOM	195	HA	PHE	116	−42.446	9.018	10.361
ATOM	196	H	PHE	116	−43.145	11.37	11.761
ATOM	197	HB1	PHE	116	−41.554	9.379	12.661
ATOM	198	HB2	PHE	116	−43.2	9.248	13.334
ATOM	199	HD2	PHE	116	−44.067	7.056	13.899
ATOM	200	HE2	PHE	116	−43.933	4.59	13.782
ATOM	201	HZ	PHE	116	−42.266	3.505	12.293
ATOM	202	HE1	PHE	116	−40.574	4.895	11.115
ATOM	203	HD1	PHE	116	−40.653	7.356	11.292
ATOM	204	N	GLY	117	−45.553	9.003	11.601
ATOM	205	CA	GLY	117	−46.816	8.297	11.412
ATOM	206	C	GLY	117	−47.161	8.218	9.944
ATOM	207	O	GLY	117	−47.586	7.171	9.482
ATOM	208	HA2	GLY	117	−47.642	8.819	11.921
ATOM	209	HA1	GLY	117	−46.734	7.286	11.841
ATOM	210	H	GLY	117	−45.537	9.823	12.179
ATOM	211	N	THR	118	−46.989	9.322	9.185
ATOM	212	CA	THR	118	−47.309	9.275	7.758
ATOM	213	C	THR	118	−46.394	8.284	7.074
ATOM	214	O	THR	118	−46.872	7.443	6.328
ATOM	215	CB	THR	118	−47.189	10.671	7.078
ATOM	216	OG1	THR	118	−48.156	11.593	7.616
ATOM	217	CG2	THR	118	−47.452	10.576	5.552
ATOM	218	HA	THR	118	−48.353	8.939	7.642
ATOM	219	H	THR	118	−46.619	10.165	9.585
ATOM	220	HB	THR	118	−46.172	11.074	7.224
ATOM	221	HG1	THR	118	−48.042	11.772	8.545
ATOM	222	HG23	THR	118	−46.685	9.964	5.055
ATOM	223	HG21	THR	118	−48.441	10.133	5.36
ATOM	224	HG22	THR	118	−47.428	11.584	5.109
ATOM	225	N	ILE	119	−45.066	8.365	7.319
ATOM	226	CA	ILE	119	−44.146	7.409	6.698
ATOM	227	C	ILE	119	−44.62	6.019	7.06
ATOM	228	O	ILE	119	−44.647	5.153	6.201
ATOM	229	CB	ILE	119	−42.666	7.612	7.158
ATOM	230	CG1	ILE	119	−42.093	8.961	6.615
ATOM	231	CG2	ILE	119	−41.766	6.418	6.721
ATOM	232	CD1	ILE	119	−40.723	9.358	7.231
ATOM	233	HA	ILE	119	−44.197	7.52	5.602
ATOM	234	H	ILE	119	−44.713	9.045	7.966
ATOM	235	HB	ILE	119	−42.662	7.637	8.26
ATOM	236	HG11	ILE	119	−41.992	8.901	5.519
ATOM	237	HG12	ILE	119	−42.792	9.783	6.833
ATOM	238	HD11	ILE	119	−39.927	8.658	6.946
ATOM	239	HD12	ILE	119	−40.424	10.356	6.873
ATOM	240	HD13	ILE	119	−40.786	9.385	8.329
ATOM	241	HG21	ILE	119	−41.695	6.369	5.624
ATOM	242	HG22	ILE	119	−40.755	6.519	7.139
ATOM	243	HG23	ILE	119	−42.156	5.457	7.085
ATOM	244	N	CYS	120	−44.991	5.786	8.336
ATOM	245	CA	CYS	120	−45.392	4.446	8.749
ATOM	246	C	CYS	120	−46.619	3.976	8.004
ATOM	247	O	CYS	120	−46.604	2.885	7.455
ATOM	248	CB	CYS	120	−45.648	4.39	10.276
ATOM	249	SG	CYS	120	−46.046	2.68	10.75
ATOM	250	HA	CYS	120	−44.567	3.763	8.514
ATOM	251	H	CYS	120	−44.977	6.518	9.019
ATOM	252	HB1	CYS	120	−44.75	4.714	10.825
ATOM	253	HB2	CYS	120	−46.487	5.046	10.55
ATOM	254	HG	CYS	120	−46.353	2.856	11.693
ATOM	255	LPG1	CYS	120	−46.539	2.416	10.365
ATOM	256	LPG2	CYS	120	−45.502	2.275	10.729
ATOM	257	N	LEU	121	−47.702	4.783	7.978
ATOM	258	CA	LEU	121	−48.923	4.328	7.315
ATOM	259	C	LEU	121	−48.625	3.987	5.872
ATOM	260	O	LEU	121	−49.063	2.952	5.393
ATOM	261	CB	LEU	121	−50.038	5.415	7.324
ATOM	262	CG	LEU	121	−50.637	5.732	8.729
ATOM	263	CD1	LEU	121	−51.515	7.013	8.644
ATOM	264	CD2	LEU	121	−51.485	4.556	9.293
ATOM	265	HA	LEU	121	−49.276	3.408	7.805
ATOM	266	H	LEU	121	−47.671	5.693	8.4
ATOM	267	HB1	LEU	121	−49.604	6.332	6.895
ATOM	268	HB2	LEU	121	−50.861	5.096	6.662
ATOM	269	HG	LEU	121	−49.826	5.935	9.447
ATOM	270	HD21	LEU	121	−50.868	3.668	9.489
ATOM	271	HD22	LEU	121	−51.953	4.847	10.246
ATOM	272	HD23	LEU	121	−52.283	4.282	8.586
ATOM	273	HD11	LEU	121	−52.347	6.861	7.939
ATOM	274	HD12	LEU	121	−51.934	7.266	9.631
ATOM	275	HD13	LEU	121	−50.917	7.872	8.301
ATOM	276	N	LEU	122	−47.884	4.857	5.154
ATOM	277	CA	LEU	122	−47.649	4.599	3.736
ATOM	278	C	LEU	122	−46.677	3.45	3.564
ATOM	279	O	LEU	122	−46.929	2.561	2.766
ATOM	280	CB	LEU	122	−47.075	5.854	3.021
ATOM	281	CG	LEU	122	−47.974	7.128	3.063
ATOM	282	CD1	LEU	122	−47.205	8.32	2.425
ATOM	283	CD2	LEU	122	−49.33	6.921	2.332
ATOM	284	HA	LEU	122	−48.593	4.308	3.249
ATOM	285	H	LEU	122	−47.476	5.666	5.587
ATOM	286	HB1	LEU	122	−46.112	6.094	3.499
ATOM	287	HB2	LEU	122	−46.887	5.596	1.966
ATOM	288	HG	LEU	122	−48.195	7.402	4.108
ATOM	289	HD21	LEU	122	−49.958	6.186	2.855
ATOM	290	HD22	LEU	122	−49.891	7.868	2.295
ATOM	291	HD23	LEU	122	−49.161	6.577	1.3
ATOM	292	HD11	LEU	122	−46.99	8.113	1.365
ATOM	293	HD12	LEU	122	−47.8	9.245	2.487
ATOM	294	HD13	LEU	122	−46.251	8.492	2.946
ATOM	295	N	GLY	123	−45.54	3.454	4.294
ATOM	296	CA	GLY	123	−44.525	2.43	4.066
ATOM	297	C	GLY	123	−44.979	1.056	4.495
ATOM	298	O	GLY	123	−44.606	0.104	3.826
ATOM	299	HA2	GLY	123	−43.599	2.672	4.606
ATOM	300	HA1	GLY	123	−44.275	2.405	2.993
ATOM	301	H	GLY	123	−45.362	4.161	4.982
ATOM	302	N	ILE	124	−45.759	0.894	5.59
ATOM	303	CA	ILE	124	−46.226	−0.453	5.926
ATOM	304	C	ILE	124	−47.066	−0.936	4.77
ATOM	305	O	ILE	124	−46.85	−2.039	4.293
ATOM	306	CB	ILE	124	−47.041	−0.578	7.254
ATOM	307	CG1	ILE	124	−46.092	−0.359	8.47
ATOM	308	CG2	ILE	124	−47.75	−1.963	7.351
ATOM	309	CD1	ILE	124	−46.78	−0.457	9.858
ATOM	310	HA	ILE	124	−45.351	−1.115	6.002
ATOM	311	H	ILE	124	−46.062	1.677	6.141
ATOM	312	HB	ILE	124	−47.822	0.202	7.257
ATOM	313	HG11	ILE	124	−45.276	−1.099	8.444
ATOM	314	HG12	ILE	124	−45.652	0.645	8.375
ATOM	315	HD11	ILE	124	−47.092	−1.486	10.089
ATOM	316	HD12	ILE	124	−46.073	−0.155	10.646
ATOM	317	HD13	ILE	124	−47.658	0.205	9.899
ATOM	318	HG21	ILE	124	−47	−2.767	7.387
ATOM	319	HG22	ILE	124	−48.382	−2.027	8.247
ATOM	320	HG23	ILE	124	−48.419	−2.146	6.497
ATOM	321	N	ILE	125	−48.044	−0.123	4.32
ATOM	322	CA	ILE	125	−48.936	−0.596	3.265
ATOM	323	C	ILE	125	−48.097	−0.909	2.048
ATOM	324	O	ILE	125	−48.209	−2.004	1.52
ATOM	325	CB	ILE	125	−50.079	0.421	2.957
ATOM	326	CG1	ILE	125	−51.049	0.514	4.179
ATOM	327	CG2	ILE	125	−50.839	0.011	1.662
ATOM	328	CD1	ILE	125	−52.043	1.705	4.103
ATOM	329	HA	ILE	125	−49.405	−1.537	3.599
ATOM	330	H	ILE	125	−48.156	0.803	4.69
ATOM	331	HB	ILE	125	−49.619	1.408	2.784
ATOM	332	HG11	ILE	125	−51.617	−0.426	4.274
ATOM	333	HG12	ILE	125	−50.472	0.641	5.109
ATOM	334	HD11	ILE	125	−52.768	1.578	3.287
ATOM	335	HD12	ILE	125	−52.608	1.778	5.045
ATOM	336	HD13	ILE	125	−51.498	2.65	3.953
ATOM	337	HG21	ILE	125	−51.291	−0.985	1.786
ATOM	338	HG22	ILE	125	−51.635	0.73	1.419
ATOM	339	HG23	ILE	125	−50.16	−0.018	0.796
ATOM	340	N	GLY	126	−47.249	0.03	1.577
ATOM	341	CA	GLY	126	−46.479	−0.244	0.366
ATOM	342	C	GLY	126	−45.643	−1.493	0.508
ATOM	343	O	GLY	126	−45.741	−2.385	−0.319
ATOM	344	HA2	GLY	126	−45.793	0.588	0.14
ATOM	345	HA1	GLY	126	−47.171	−0.352	−0.484
ATOM	346	H	GLY	126	−47.15	0.921	2.03
ATOM	347	N	ASN	127	−44.791	−1.579	1.551
ATOM	348	CA	ASN	127	−43.893	−2.73	1.652
ATOM	349	C	ASN	127	−44.662	−4.015	1.883
ATOM	350	O	ASN	127	−44.339	−5.013	1.256
ATOM	351	CB	ASN	127	−42.836	−2.496	2.76
ATOM	352	CG	ASN	127	−41.959	−1.326	2.383
ATOM	353	OD1	ASN	127	−41.217	−1.453	1.424
ATOM	354	ND2	ASN	127	−42.005	−0.175	3.086
ATOM	355	HA	ASN	127	−43.35	−2.833	0.697
ATOM	356	H	ASN	127	−44.762	−0.856	2.248
ATOM	357	HB1	ASN	127	−43.353	−2.326	3.712
ATOM	358	HB2	ASN	127	−42.198	−3.383	2.875
ATOM	359	HD22	ASN	127	−41.416	0.592	2.816
ATOM	360	HD21	ASN	127	−42.614	−0.064	3.87
ATOM	361	N	SER	128	−45.691	−4.04	2.761
ATOM	362	CA	SER	128	−46.468	−5.272	2.924
ATOM	363	C	SER	128	−47.094	−5.642	1.6
ATOM	364	O	SER	128	−46.996	−6.786	1.182
ATOM	365	CB	SER	128	−47.607	−5.152	3.972
ATOM	366	OG	SER	128	−47.048	−5.009	5.289
ATOM	367	HA	SER	128	−45.797	−6.088	3.234
ATOM	368	H	SER	128	−45.96	−3.221	3.275
ATOM	369	HB1	SER	128	−48.249	−4.288	3.731
ATOM	370	HB2	SER	128	−48.223	−6.068	3.942
ATOM	371	HG	SER	128	−47.711	−4.929	5.969
ATOM	372	N	THR	129	−47.749	−4.669	0.931
ATOM	373	CA	THR	129	−48.36	−4.956	−0.363
ATOM	374	C	THR	129	−47.338	−5.555	−1.3
ATOM	375	O	THR	129	−47.644	−6.537	−1.96
ATOM	376	CB	THR	129	−48.97	−3.66	−0.963
ATOM	377	OG1	THR	129	−50.069	−3.27	−0.118
ATOM	378	CG2	THR	129	−49.464	−3.876	−2.413
ATOM	379	HA	THR	129	−49.175	−5.682	−0.213
ATOM	380	H	THR	129	−47.824	−3.739	1.304
ATOM	381	HB	THR	129	−48.201	−2.868	−0.978
ATOM	382	HG1	THR	129	−50.469	−2.449	−0.382
ATOM	383	HG23	THR	129	−48.611	−4.09	−3.074
ATOM	384	HG21	THR	129	−50.173	−4.718	−2.444
ATOM	385	HG22	THR	129	−49.968	−2.969	−2.783
ATOM	386	N	VAL	130	−46.117	−4.982	−1.378
ATOM	387	CA	VAL	130	−45.117	−5.543	−2.285
ATOM	388	C	VAL	130	−44.836	−6.983	−1.921
ATOM	389	O	VAL	130	−44.83	−7.824	−2.806
ATOM	390	CB	VAL	130	−43.79	−4.726	−2.304
ATOM	391	CG1	VAL	130	−42.648	−5.488	−3.032
ATOM	392	CG2	VAL	130	−43.994	−3.355	−3.008
ATOM	393	HA	VAL	130	−45.538	−5.524	−3.3
ATOM	394	H	VAL	130	−45.883	−4.184	−0.815
ATOM	395	HB	VAL	130	−43.469	−4.555	−1.262
ATOM	396	HG11	VAL	130	−42.958	−5.753	−4.053
ATOM	397	HG12	VAL	130	−41.764	−4.839	−3.096
ATOM	398	HG13	VAL	130	−42.358	−6.405	−2.496
ATOM	399	HG21	VAL	130	−44.836	−2.798	−2.579
ATOM	400	HG22	VAL	130	−43.084	−2.747	−2.901
ATOM	401	HG23	VAL	130	−44.191	−3.498	−4.08
ATOM	402	N	ILE	131	−44.586	−7.301	−0.633
ATOM	403	CA	ILE	131	−44.219	−8.679	−0.293
ATOM	404	C	ILE	131	−45.377	−9.574	−0.644
ATOM	405	O	ILE	131	−45.185	−10.553	−1.349
ATOM	406	CB	ILE	131	−43.862	−8.871	1.211
ATOM	407	CG1	ILE	131	−42.571	−8.071	1.544
ATOM	408	CG2	ILE	131	−43.679	−10.374	1.572
ATOM	409	CD1	ILE	131	−42.457	−7.705	3.042
ATOM	410	HA	ILE	131	−43.344	−8.977	−0.896
ATOM	411	H	ILE	131	−44.668	−6.603	0.086
ATOM	412	HB	ILE	131	−44.698	−8.472	1.809
ATOM	413	HG11	ILE	131	−41.674	−8.618	1.213
ATOM	414	HG12	ILE	131	−42.603	−7.128	0.99
ATOM	415	HD11	ILE	131	−42.391	−8.597	3.68
ATOM	416	HD12	ILE	131	−41.564	−7.087	3.204
ATOM	417	HD13	ILE	131	−43.336	−7.116	3.337
ATOM	418	HG21	ILE	131	−42.875	−10.813	0.962
ATOM	419	HG22	ILE	131	−43.415	−10.497	2.632
ATOM	420	HG23	ILE	131	−44.603	−10.947	1.395
ATOM	421	N	PHE	132	−46.59	−9.249	−0.15
ATOM	422	CA	PHE	132	−47.734	−10.104	−0.439
ATOM	423	C	PHE	132	−47.839	−10.323	−1.927
ATOM	424	O	PHE	132	−48.001	−11.452	−2.363
ATOM	425	CB	PHE	132	−49.049	−9.447	0.056
ATOM	426	CG	PHE	132	−50.257	−10.296	−0.362
ATOM	427	CD1	PHE	132	−51.009	−9.962	−1.494
ATOM	428	CD2	PHE	132	−50.615	−11.416	0.396
ATOM	429	CE1	PHE	132	−52.151	−10.698	−1.824
ATOM	430	CE2	PHE	132	−51.746	−12.165	0.057
ATOM	431	CZ	PHE	132	−52.525	−11.794	−1.041
ATOM	432	HA	PHE	132	−47.595	−11.075	0.064
ATOM	433	H	PHE	132	−46.72	−8.426	0.411
ATOM	434	HB1	PHE	132	−49.026	−9.351	1.153
ATOM	435	HB2	PHE	132	−49.144	−8.432	−0.361
ATOM	436	HD2	PHE	132	−50.016	−11.708	1.253
ATOM	437	HE2	PHE	132	−52.019	−13.034	0.649
ATOM	438	HZ	PHE	132	−53.421	−12.358	−1.284
ATOM	439	HE1	PHE	132	−52.747	−10.417	−2.687
ATOM	440	HD1	PHE	132	−50.711	−9.128	−2.123
ATOM	441	N	ALA	133	−47.757	−9.242	−2.729
ATOM	442	CA	ALA	133	−47.975	−9.396	−4.162
ATOM	443	C	ALA	133	−46.844	−10.121	−4.857
ATOM	444	O	ALA	133	−47.134	−10.928	−5.727
ATOM	445	CB	ALA	133	−48.209	−8.016	−4.819
ATOM	446	HA	ALA	133	−48.894	−9.991	−4.291
ATOM	447	H	ALA	133	−47.567	−8.33	−2.353
ATOM	448	HB1	ALA	133	−48.262	−8.108	−5.913
ATOM	449	HB2	ALA	133	−49.15	−7.589	−4.442
ATOM	450	HB3	ALA	133	−47.387	−7.337	−4.564
ATOM	451	N	VAL	134	−45.56	−9.87	−4.514
ATOM	452	CA	VAL	134	−44.486	−10.641	−5.145
ATOM	453	C	VAL	134	−44.653	−12.082	−4.718
ATOM	454	O	VAL	134	−44.691	−12.958	−5.567
ATOM	455	CB	VAL	134	−43.046	−10.154	−4.791
ATOM	456	CG1	VAL	134	−41.977	−11.128	−5.366
ATOM	457	CG2	VAL	134	−42.764	−8.727	−5.339
ATOM	458	HA	VAL	134	−44.597	−10.589	−6.241
ATOM	459	H	VAL	134	−45.337	−9.208	−3.793
ATOM	460	HB	VAL	134	−42.942	−10.127	−3.692
ATOM	461	HG11	VAL	134	−42.107	−11.246	−6.452
ATOM	462	HG12	VAL	134	−40.964	−10.74	−5.184
ATOM	463	HG13	VAL	134	−42.053	−12.122	−4.897
ATOM	464	HG21	VAL	134	−43.532	−8.019	−5.003
ATOM	465	HG22	VAL	134	−41.787	−8.364	−4.984
ATOM	466	HG23	VAL	134	−42.748	−8.735	−6.439
ATOM	467	N	VAL	135	−44.754	−12.347	−3.397
ATOM	468	CA	VAL	135	−44.849	−13.731	−2.93
ATOM	469	C	VAL	135	−46.077	−14.395	−3.514
ATOM	470	O	VAL	135	−46.029	−15.586	−3.778
ATOM	471	CB	VAL	135	−44.843	−13.813	−1.372
ATOM	472	CG1	VAL	135	−45.164	−15.248	−0.865
ATOM	473	CG2	VAL	135	−43.464	−13.365	−0.804
ATOM	474	HA	VAL	135	−43.972	−14.284	−3.306
ATOM	475	H	VAL	135	−44.787	−11.599	−2.731
ATOM	476	HB	VAL	135	−45.629	−13.141	−0.984
ATOM	477	HG11	VAL	135	−44.455	−15.972	−1.294
ATOM	478	HG12	VAL	135	−45.09	−15.293	0.232
ATOM	479	HG13	VAL	135	−46.186	−15.548	−1.142
ATOM	480	HG21	VAL	135	−43.187	−12.355	−1.142
ATOM	481	HG22	VAL	135	−43.489	−13.36	0.297
ATOM	482	HG23	VAL	135	−42.674	−14.059	−1.128
ATOM	483	N	LYS	136	−47.193	−13.666	−3.738
ATOM	484	CA	LYS	136	−48.38	−14.311	−4.303
ATOM	485	C	LYS	136	−48.119	−14.994	−5.631
ATOM	486	O	LYS	136	−48.946	−15.817	−5.992
ATOM	487	CB	LYS	136	−49.567	−13.308	−4.41
ATOM	488	CG	LYS	136	−50.884	−13.942	−4.945
ATOM	489	CD	LYS	136	−52.107	−13.027	−4.661
ATOM	490	CE	LYS	136	−53.436	−13.622	−5.202
ATOM	491	NZ	LYS	136	−54.611	−12.819	−4.777
ATOM	492	HA	LYS	136	−48.679	−15.103	−3.596
ATOM	493	H	LYS	136	−47.231	−12.693	−3.498
ATOM	494	HB1	LYS	136	−49.758	−12.915	−3.399
ATOM	495	HB2	LYS	136	−49.278	−12.466	−5.059
ATOM	496	HG1	LYS	136	−50.805	−14.113	−6.031
ATOM	497	HG2	LYS	136	−51.049	−14.912	−4.449
ATOM	498	HD1	LYS	136	−52.201	−12.905	−3.572
ATOM	499	HD2	LYS	136	−51.936	−12.035	−5.109
ATOM	500	HE1	LYS	136	−53.386	−13.667	−6.304
ATOM	501	HE2	LYS	136	−53.548	−14.654	−4.827
ATOM	502	HZ1	LYS	136	−54.554	−11.786	−5.093
ATOM	503	HZ2	LYS	136	−55.534	−13.217	−5.18
ATOM	504	HZ3	LYS	136	−54.728	−12.808	−3.701
ATOM	505	N	LYS	137	−47.025	−14.713	−6.384
ATOM	506	CA	LYS	137	−46.802	−15.406	−7.657
ATOM	507	C	LYS	137	−45.378	−15.905	−7.774
ATOM	508	O	LYS	137	−44.519	−15.373	−7.091
ATOM	509	CB	LYS	137	−47.153	−14.459	−8.835
ATOM	510	CG	LYS	137	−48.605	−13.918	−8.705
ATOM	511	CD	LYS	137	−49.017	−13.102	−9.961
ATOM	512	CE	LYS	137	−50.469	−12.549	−9.895
ATOM	513	NZ	LYS	137	−50.667	−11.485	−8.88
ATOM	514	HA	LYS	137	−47.436	−16.305	−7.734
ATOM	515	H	LYS	137	−46.345	−14.028	−6.108
ATOM	516	HB1	LYS	137	−46.445	−13.614	−8.837
ATOM	517	HB2	LYS	137	−47.037	−15.008	−9.784
ATOM	518	HG1	LYS	137	−49.303	−14.761	−8.581
ATOM	519	HG2	LYS	137	−48.661	−13.283	−7.807
ATOM	520	HD1	LYS	137	−48.314	−12.27	−10.096
ATOM	521	HD2	LYS	137	−48.934	−13.76	−10.843
ATOM	522	HE1	LYS	137	−50.714	−12.135	−10.888
ATOM	523	HE2	LYS	137	−51.163	−13.386	−9.704
ATOM	524	HZ1	LYS	137	−50.061	−10.602	−9.034
ATOM	525	HZ2	LYS	137	−51.687	−11.136	−8.878
ATOM	526	HZ3	LYS	137	−50.508	−11.817	−7.865
ATOM	527	N	SER	138	−45.101	−16.928	−8.622
ATOM	528	CA	SER	138	−43.777	−17.553	−8.63
ATOM	529	C	SER	138	−43.327	−17.857	−10.042
ATOM	530	O	SER	138	−43.119	−19.012	−10.378
ATOM	531	CB	SER	138	−43.842	−18.836	−7.762
ATOM	532	OG	SER	138	−44.23	−18.475	−6.425
ATOM	533	HA	SER	138	−43.004	−16.897	−8.197
ATOM	534	H	SER	138	−45.809	−17.34	−9.197
ATOM	535	HB1	SER	138	−44.582	−19.53	−8.195
ATOM	536	HB2	SER	138	−42.855	−19.33	−7.749
ATOM	537	HG	SER	138	−44.295	−19.223	−5.838
ATOM	538	N	LYS	139	−43.151	−16.817	−10.887
ATOM	539	CA	LYS	139	−42.596	−17.029	−12.226
ATOM	540	C	LYS	139	−41.706	−15.845	−12.534
ATOM	541	O	LYS	139	−42.192	−14.868	−13.086
ATOM	542	CB	LYS	139	−43.721	−17.217	−13.279
ATOM	543	CG	LYS	139	−43.126	−17.45	−14.699
ATOM	544	CD	LYS	139	−44.223	−17.779	−15.749
ATOM	545	CE	LYS	139	−43.607	−17.983	−17.162
ATOM	546	NZ	LYS	139	−44.628	−18.386	−18.161
ATOM	547	HA	LYS	139	−41.972	−17.938	−12.251
ATOM	548	H	LYS	139	−43.386	−15.887	−10.6
ATOM	549	HB1	LYS	139	−44.323	−18.092	−12.984
ATOM	550	HB2	LYS	139	−44.382	−16.336	−13.279
ATOM	551	HG1	LYS	139	−42.576	−16.553	−15.028
ATOM	552	HG2	LYS	139	−42.414	−18.29	−14.66
ATOM	553	HD1	LYS	139	−44.748	−18.699	−15.444
ATOM	554	HD2	LYS	139	−44.957	−16.957	−15.783
ATOM	555	HE1	LYS	139	−43.127	−17.042	−17.482
ATOM	556	HE2	LYS	139	−42.824	−18.76	−17.109
ATOM	557	HZ1	LYS	139	−45.414	−17.649	−18.258
ATOM	558	HZ2	LYS	139	−44.197	−18.514	−19.146
ATOM	559	HZ3	LYS	139	−45.098	−19.326	−17.904
ATOM	560	N	LEU	140	−40.408	−15.911	−12.157
ATOM	561	CA	LEU	140	−39.484	−14.806	−12.4
ATOM	562	C	LEU	140	−38.466	−15.342	−13.392
ATOM	563	O	LEU	140	−37.993	−16.447	−13.175
ATOM	564	CB	LEU	140	−38.828	−14.387	−11.05
ATOM	565	CG	LEU	140	−39.84	−14.149	−9.884
ATOM	566	CD1	LEU	140	−39.115	−14.123	−8.507
ATOM	567	CD2	LEU	140	−40.635	−12.827	−10.055
ATOM	568	HA	LEU	140	−39.99	−13.927	−12.825
ATOM	569	H	LEU	140	−40.03	−16.724	−11.707
ATOM	570	HB1	LEU	140	−38.184	−15.219	−10.741
ATOM	571	HB2	LEU	140	−38.197	−13.498	−11.201
ATOM	572	HG	LEU	140	−40.559	−14.986	−9.85
ATOM	573	HD21	LEU	140	−41.11	−12.779	−11.04
ATOM	574	HD22	LEU	140	−41.42	−12.745	−9.286
ATOM	575	HD23	LEU	140	−39.964	−11.964	−9.956
ATOM	576	HD11	LEU	140	−38.414	−13.279	−8.458
ATOM	577	HD12	LEU	140	−39.845	−14.012	−7.69
ATOM	578	HD13	LEU	140	−38.553	−15.055	−8.337
ATOM	579	N	HIS	141	−38.118	−14.625	−14.486
ATOM	580	CA	HIS	141	−37.131	−15.151	−15.438
ATOM	581	C	HIS	141	−35.719	−14.827	−14.995
ATOM	582	O	HIS	141	−35.546	−14.14	−13.999
ATOM	583	CB	HIS	141	−37.42	−14.581	−16.855
ATOM	584	CG	HIS	141	−38.75	−15.144	−17.355
ATOM	585	CD2	HIS	141	−39.982	−14.517	−17.461
ATOM	586	CE1	HIS	141	−40.19	−16.584	−18.158
ATOM	587	HA	HIS	141	−37.204	−16.25	−15.504
ATOM	588	H	HIS	141	−38.511	−13.72	−14.651
ATOM	589	HB1	HIS	141	−37.45	−13.481	−16.84
ATOM	590	HB2	HIS	141	−36.656	−14.889	−17.583
ATOM	591	HD2	HIS	141	−40.211	−13.49	−17.208
ATOM	592	N2	HIS	141	−40.847	−15.428	−17.944
ATOM	593	HE1	HIS	141	−40.616	−17.497	−18.561
ATOM	594	N1	HIS	141	−38.909	−16.408	−17.787
ATOM	595	N	TRP	142	−34.675	−15.314	−15.709
ATOM	596	CA	TRP	142	−33.314	−14.88	−15.385
ATOM	597	C	TRP	142	−33.207	−13.391	−15.652
ATOM	598	O	TRP	142	−34.051	−12.869	−16.362
ATOM	599	CB	TRP	142	−32.204	−15.677	−16.127
ATOM	600	CG	TRP	142	−31.927	−15.171	−17.521
ATOM	601	CD1	TRP	142	−32.759	−15.153	−18.577
ATOM	602	CD2	TRP	142	−30.619	−14.584	−17.991
ATOM	603	NE1	TRP	142	−32.145	−14.636	−19.61
ATOM	604	CE2	TRP	142	−30.88	−14.283	−19.314
ATOM	605	CE3	TRP	142	−29.376	−14.332	−17.412
ATOM	606	CZ2	TRP	142	−29.916	−13.706	−20.141
ATOM	607	CZ3	TRP	142	−28.394	−13.76	−18.232
ATOM	608	CH2	TRP	142	−28.663	−13.444	−19.573
ATOM	609	HA	TRP	142	−33.175	−15.053	−14.303
ATOM	610	HB1	TRP	142	−31.265	−15.599	−15.557
ATOM	611	HB2	TRP	142	−32.471	−16.744	−16.169
ATOM	612	HE1	TRP	142	−32.575	−14.516	−20.54
ATOM	613	HD1	TRP	142	−33.788	−15.509	−18.59
ATOM	614	HZ2	TRP	142	−30.132	−13.471	−21.178
ATOM	615	HH2	TRP	142	−27.887	−12.988	−20.18
ATOM	616	HZ3	TRP	142	−27.41	−13.556	−17.82
ATOM	617	HE3	TRP	142	−29.175	−14.565	−16.374
ATOM	618	H	TRP	142	−34.814	−15.939	−16.477
ATOM	619	N	CYS	143	−32.214	−12.682	−15.065
ATOM	620	CA	CYS	143	−32.197	−11.214	−15.119
ATOM	621	C	CYS	143	−33.421	−10.589	−14.475
ATOM	622	O	CYS	143	−33.652	−9.411	−14.702
ATOM	623	CB	CYS	143	−31.982	−10.668	−16.557
ATOM	624	SG	CYS	143	−30.466	−11.407	−17.246
ATOM	625	HA	CYS	143	−31.347	−10.846	−14.516
ATOM	626	HB1	CYS	143	−32.838	−10.911	−17.204
ATOM	627	HB2	CYS	143	−31.856	−9.573	−16.544
ATOM	628	HG	CYS	143	−30.51	−11.008	−18.171
ATOM	629	LPG1	CYS	143	−29.91	−11.211	−16.909
ATOM	630	LPG2	CYS	143	−30.496	−12.085	−17.258
ATOM	631	H	CYS	143	−31.517	−13.145	−14.516
ATOM	632	N	ASN	144	−34.206	−11.341	−13.665
ATOM	633	CA	ASN	144	−35.392	−10.789	−13.003
ATOM	634	C	ASN	144	−35.478	−11.371	−11.603
ATOM	635	O	ASN	144	−35.521	−10.601	−10.658
ATOM	636	CB	ASN	144	−36.691	−11.031	−13.807
ATOM	637	CG	ASN	144	−36.622	−10.352	−15.153
ATOM	638	OD1	ASN	144	−37.177	−9.275	−15.307
ATOM	639	ND2	ASN	144	−35.945	−10.947	−16.157
ATOM	640	HA	ASN	144	−35.298	−9.697	−12.91
ATOM	641	HB1	ASN	144	−36.865	−12.102	−13.949
ATOM	642	HB2	ASN	144	−37.541	−10.635	−13.234
ATOM	643	HD22	ASN	144	−35.886	−10.493	−17.045
ATOM	644	HD21	ASN	144	−35.481	−11.826	−16.03
ATOM	645	H	ASN	144	−33.989	−12.3	−13.502
ATOM	646	N	ASN	145	−35.467	−12.717	−11.434
ATOM	647	CA	ASN	145	−35.277	−13.308	−10.104
ATOM	648	C	ASN	145	−34.37	−12.461	−9.242
ATOM	649	O	ASN	145	−34.793	−12.043	−8.178
ATOM	650	CB	ASN	145	−34.606	−14.713	−10.158
ATOM	651	CG	ASN	145	−35.599	−15.81	−10.439
ATOM	652	OD1	ASN	145	−36.093	−16.417	−9.502
ATOM	653	ND2	ASN	145	−35.933	−16.098	−11.71
ATOM	654	HA	ASN	145	−36.25	−13.39	−9.595
ATOM	655	HB1	ASN	145	−33.812	−14.71	−10.919
ATOM	656	HB2	ASN	145	−34.129	−14.963	−9.199
ATOM	657	HD22	ASN	145	−36.626	−16.799	−11.882
ATOM	658	HD21	ASN	145	−35.528	−15.624	−12.488
ATOM	659	H	ASN	145	−35.58	−13.329	−12.215
ATOM	660	N	VAL	146	−33.115	−12.208	−9.67
ATOM	661	CA	VAL	146	−32.177	−11.513	−8.79
ATOM	662	C	VAL	146	−32.732	−10.166	−8.349
ATOM	663	O	VAL	146	−32.933	−10.01	−7.152
ATOM	664	CB	VAL	146	−30.727	−11.501	−9.372
ATOM	665	CG1	VAL	146	−29.809	−10.566	−8.542
ATOM	666	CG2	VAL	146	−30.106	−12.929	−9.419
ATOM	667	HA	VAL	146	−32.107	−12.114	−7.869
ATOM	668	H	VAL	146	−32.811	−12.51	−10.574
ATOM	669	HB	VAL	146	−30.75	−11.135	−10.41
ATOM	670	HG11	VAL	146	−29.834	−10.854	−7.479
ATOM	671	HG12	VAL	146	−28.77	−10.629	−8.898
ATOM	672	HG13	VAL	146	−30.144	−9.524	−8.64
ATOM	673	HG21	VAL	146	−30.753	−13.635	−9.961
ATOM	674	HG22	VAL	146	−29.131	−12.902	−9.931
ATOM	675	HG23	VAL	146	−29.945	−13.315	−8.402
ATOM	676	N	PRO	147	−33.012	−9.151	−9.205
ATOM	677	CA	PRO	147	−33.523	−7.891	−8.681
ATOM	678	C	PRO	147	−34.892	−8.007	−8.042
ATOM	679	O	PRO	147	−35.1	−7.371	−7.02
ATOM	680	CB	PRO	147	−33.464	−6.994	−9.943
ATOM	681	CG	PRO	147	−33.573	−8.001	−11.11
ATOM	682	CD	PRO	147	−32.744	−9.214	−10.632
ATOM	683	HA	PRO	147	−32.828	−7.506	−7.928
ATOM	684	HD2	PRO	147	−31.678	−9.015	−10.813
ATOM	685	HD1	PRO	147	−33.048	−10.138	−11.14
ATOM	686	HG2	PRO	147	−33.2	−7.626	−12.072
ATOM	687	HG1	PRO	147	−34.635	−8.252	−11.222
ATOM	688	HB1	PRO	147	−34.246	−6.217	−9.958
ATOM	689	HB2	PRO	147	−32.477	−6.503	−10.011
ATOM	690	N	ASP	148	−35.845	−8.801	−8.581
ATOM	691	CA	ASP	148	−37.138	−8.936	−7.906
ATOM	692	C	ASP	148	−36.917	−9.463	−6.504
ATOM	693	O	ASP	148	−37.553	−8.999	−5.571
ATOM	694	CB	ASP	148	−38.092	−9.92	−8.637
ATOM	695	CG	ASP	148	−38.594	−9.383	−9.953
ATOM	696	OD1	ASP	148	−38.601	−10.134	−10.966
ATOM	697	OD2	ASP	148	−39.028	−8.201	−10.005
ATOM	698	HA	ASP	148	−37.625	−7.949	−7.842
ATOM	699	H	ASP	148	−35.673	−9.345	−9.404
ATOM	700	HB1	ASP	148	−37.579	−10.881	−8.793
ATOM	701	HB2	ASP	148	−38.982	−10.103	−8.014
ATOM	702	N	ILE	149	−36.012	−10.451	−6.336
ATOM	703	CA	ILE	149	−35.801	−11.038	−5.014
ATOM	704	C	ILE	149	−35.164	−10.028	−4.079
ATOM	705	O	ILE	149	−35.58	−9.983	−2.931
ATOM	706	CB	ILE	149	−35.065	−12.41	−5.131
ATOM	707	CG1	ILE	149	−36.039	−13.473	−5.733
ATOM	708	CG2	ILE	149	−34.495	−12.861	−3.762
ATOM	709	CD1	ILE	149	−35.341	−14.776	−6.206
ATOM	710	HA	ILE	149	−36.792	−11.257	−4.579
ATOM	711	H	ILE	149	−35.473	−10.787	−7.113
ATOM	712	HB	ILE	149	−34.2	−12.274	−5.799
ATOM	713	HG11	ILE	149	−36.814	−13.73	−4.992
ATOM	714	HG12	ILE	149	−36.55	−13.041	−6.608
ATOM	715	HD11	ILE	149	−34.955	−15.369	−5.365
ATOM	716	HD12	ILE	149	−36.055	−15.406	−6.76
ATOM	717	HD13	ILE	149	−34.507	−14.529	−6.876
ATOM	718	HG21	ILE	149	−35.276	−12.815	−2.987
ATOM	719	HG22	ILE	149	−34.089	−13.881	−3.785
ATOM	720	HG23	ILE	149	−33.665	−12.19	−3.497
ATOM	721	N	PHE	150	−34.19	−9.178	−4.486
ATOM	722	CA	PHE	150	−33.745	−8.144	−3.545
ATOM	723	C	PHE	150	−34.932	−7.33	−3.09
ATOM	724	O	PHE	150	−34.998	−6.966	−1.929
ATOM	725	CB	PHE	150	−32.833	−7.014	−4.093
ATOM	726	CG	PHE	150	−31.503	−7.476	−4.686
ATOM	727	CD1	PHE	150	−31.127	−7.006	−5.947
ATOM	728	CD2	PHE	150	−30.648	−8.337	−3.994
ATOM	729	CE1	PHE	150	−30.022	−7.545	−6.608
ATOM	730	CE2	PHE	150	−29.478	−8.787	−4.611
ATOM	731	CZ	PHE	150	−29.204	−8.457	−5.942
ATOM	732	HA	PHE	150	−33.277	−8.631	−2.674
ATOM	733	H	PHE	150	−33.807	−9.211	−5.414
ATOM	734	HB1	PHE	150	−33.393	−6.443	−4.852
ATOM	735	HB2	PHE	150	−32.578	−6.325	−3.273
ATOM	736	HD2	PHE	150	−30.875	−8.652	−2.982
ATOM	737	HE2	PHE	150	−28.787	−9.391	−4.046
ATOM	738	HZ	PHE	150	−28.362	−8.9	−6.463
ATOM	739	HE1	PHE	150	−29.804	−7.259	−7.63
ATOM	740	HD1	PHE	150	−31.699	−6.213	−6.411
ATOM	741	N	ILE	151	−35.861	−6.996	−4.01
ATOM	742	CA	ILE	151	−36.937	−6.081	−3.64
ATOM	743	C	ILE	151	−37.789	−6.704	−2.552
ATOM	744	O	ILE	151	−38.339	−5.969	−1.744
ATOM	745	CB	ILE	151	−37.681	−5.568	−4.909
ATOM	746	CG1	ILE	151	−36.706	−4.698	−5.77
ATOM	747	CG2	ILE	151	−38.946	−4.769	−4.501
ATOM	748	CD1	ILE	151	−37.179	−4.47	−7.228
ATOM	749	HA	ILE	151	−36.473	−5.198	−3.175
ATOM	750	H	ILE	151	−35.822	−7.361	−4.945
ATOM	751	HB	ILE	151	−38.009	−6.442	−5.496
ATOM	752	HG11	ILE	151	−36.57	−3.714	−5.298
ATOM	753	HG12	ILE	151	−35.713	−5.169	−5.83
ATOM	754	HD11	ILE	151	−38.069	−3.833	−7.235
ATOM	755	HD12	ILE	151	−36.393	−3.958	−7.808
ATOM	756	HD13	ILE	151	−37.412	−5.423	−7.724
ATOM	757	HG21	ILE	151	−38.687	−3.94	−3.825
ATOM	758	HG22	ILE	151	−39.455	−4.358	−5.38
ATOM	759	HG23	ILE	151	−39.651	−5.44	−3.989
ATOM	760	N	ILE	152	−37.881	−8.052	−2.467
ATOM	761	CA	ILE	152	−38.504	−8.656	−1.288
ATOM	762	C	ILE	152	−37.66	−8.239	−0.098
ATOM	763	O	ILE	152	−38.209	−7.768	0.886
ATOM	764	CB	ILE	152	−38.598	−10.215	−1.34
ATOM	765	CG1	ILE	152	−39.452	−10.7	−2.553
ATOM	766	CG2	ILE	152	−39.164	−10.774	−0.001
ATOM	767	CD1	ILE	152	−39.422	−12.243	−2.744
ATOM	768	HA	ILE	152	−39.524	−8.252	−1.174
ATOM	769	H	ILE	152	−37.437	−8.643	−3.143
ATOM	770	HB	ILE	152	−37.576	−10.612	−1.457
ATOM	771	HG11	ILE	152	−40.495	−10.363	−2.436
ATOM	772	HG12	ILE	152	−39.062	−10.256	−3.481
ATOM	773	HD11	ILE	152	−40.014	−12.756	−1.971
ATOM	774	HD12	ILE	152	−39.847	−12.519	−3.721
ATOM	775	HD13	ILE	152	−38.387	−12.616	−2.71
ATOM	776	HG21	ILE	152	−40.201	−10.436	0.144
ATOM	777	HG22	ILE	152	−39.149	−11.873	0.015
ATOM	778	HG23	ILE	152	−38.565	−10.441	0.859
ATOM	779	N	ASN	153	−36.318	−8.405	−0.166
ATOM	780	CA	ASN	153	−35.472	−8.049	0.976
ATOM	781	C	ASN	153	−35.652	−6.589	1.327
ATOM	782	O	ASN	153	−35.829	−6.294	2.497
ATOM	783	CB	ASN	153	−33.964	−8.331	0.711
ATOM	784	CG	ASN	153	−33.095	−8.346	1.948
ATOM	785	OD1	ASN	153	−33.607	−8.406	3.053
ATOM	786	ND2	ASN	153	−31.753	−8.314	1.799
ATOM	787	HA	ASN	153	−35.799	−8.675	1.823
ATOM	788	H	ASN	153	−35.889	−8.771	−0.995
ATOM	789	HB1	ASN	153	−33.87	−9.328	0.264
ATOM	790	HB2	ASN	153	−33.561	−7.596	−0.002
ATOM	791	HD22	ASN	153	−31.17	−8.313	2.612
ATOM	792	HD21	ASN	153	−31.324	−8.294	0.896
ATOM	793	N	LEU	154	−35.623	−5.655	0.346
ATOM	794	CA	LEU	154	−35.834	−4.241	0.674
ATOM	795	C	LEU	154	−37.148	−4.108	1.404
ATOM	796	O	LEU	154	−37.226	−3.398	2.393
ATOM	797	CB	LEU	154	−35.919	−3.288	−0.559
ATOM	798	CG	LEU	154	−34.587	−3.137	−1.355
ATOM	799	CD1	LEU	154	−34.808	−2.434	−2.723
ATOM	800	CD2	LEU	154	−33.524	−2.322	−0.563
ATOM	801	HA	LEU	154	−35.034	−3.913	1.351
ATOM	802	H	LEU	154	−35.497	−5.925	−0.609
ATOM	803	HB1	LEU	154	−36.708	−3.679	−1.22
ATOM	804	HB2	LEU	154	−36.235	−2.285	−0.229
ATOM	805	HG	LEU	154	−34.218	−4.147	−1.584
ATOM	806	HD21	LEU	154	−33.278	−2.783	0.402
ATOM	807	HD22	LEU	154	−32.596	−2.241	−1.15
ATOM	808	HD23	LEU	154	−33.894	−1.305	−0.363
ATOM	809	HD11	LEU	154	−35.036	−1.373	−2.574
ATOM	810	HD12	LEU	154	−33.902	−2.504	−3.345
ATOM	811	HD13	LEU	154	−35.64	−2.89	−3.273
ATOM	812	N	SER	155	−38.211	−4.781	0.923
ATOM	813	CA	SER	155	−39.513	−4.592	1.554
ATOM	814	C	SER	155	−39.527	−5.193	2.946
ATOM	815	O	SER	155	−40.066	−4.572	3.849
ATOM	816	CB	SER	155	−40.633	−5.184	0.664
ATOM	817	OG	SER	155	−40.736	−4.516	−0.607
ATOM	818	HA	SER	155	−39.708	−3.511	1.634
ATOM	819	H	SER	155	−38.122	−5.406	0.143
ATOM	820	HB1	SER	155	−40.456	−6.261	0.519
ATOM	821	HB2	SER	155	−41.596	−5.037	1.172
ATOM	822	HG	SER	155	−39.962	−4.621	−1.153
ATOM	823	N	VAL	156	−38.942	−6.393	3.165
ATOM	824	CA	VAL	156	−38.882	−6.944	4.525
ATOM	825	C	VAL	156	−38.073	−6.004	5.388
ATOM	826	O	VAL	156	−38.521	−5.624	6.458
ATOM	827	CB	VAL	156	−38.266	−8.376	4.559
ATOM	828	CG1	VAL	156	−37.94	−8.824	6.014
ATOM	829	CG2	VAL	156	−39.229	−9.401	3.896
ATOM	830	HA	VAL	156	−39.896	−6.998	4.952
ATOM	831	H	VAL	156	−38.501	−6.884	2.411
ATOM	832	HB	VAL	156	−37.319	−8.371	3.992
ATOM	833	HG11	VAL	156	−38.842	−8.769	6.642
ATOM	834	HG12	VAL	156	−37.57	−9.861	6.021
ATOM	835	HG13	VAL	156	−37.161	−8.188	6.463
ATOM	836	HG21	VAL	156	−39.519	−9.08	2.885
ATOM	837	HG22	VAL	156	−38.745	−10.387	3.818
ATOM	838	HG23	VAL	156	−40.143	−9.511	4.5
ATOM	839	N	VAL	157	−36.868	−5.617	4.923
ATOM	840	CA	VAL	157	−36.055	−4.649	5.66
ATOM	841	C	VAL	157	−36.907	−3.458	6.04
ATOM	842	O	VAL	157	−36.975	−3.098	7.206
ATOM	843	CB	VAL	157	−34.85	−4.201	4.776
ATOM	844	CG1	VAL	157	−34.257	−2.836	5.199
ATOM	845	CG2	VAL	157	−33.731	−5.279	4.747
ATOM	846	HA	VAL	157	−35.678	−5.112	6.585
ATOM	847	H	VAL	157	−36.537	−5.975	4.048
ATOM	848	HB	VAL	157	−35.208	−4.054	3.748
ATOM	849	HG11	VAL	157	−33.894	−2.879	6.236
ATOM	850	HG12	VAL	157	−34.998	−2.028	5.113
ATOM	851	HG13	VAL	157	−33.425	−2.598	4.519
ATOM	852	HG21	VAL	157	−34.138	−6.27	4.503
ATOM	853	HG22	VAL	157	−32.983	−5.019	3.984
ATOM	854	HG23	VAL	157	−33.231	−5.335	5.725
ATOM	855	N	ASP	158	−37.564	−2.821	5.049
ATOM	856	CA	ASP	158	−38.346	−1.626	5.346
ATOM	857	C	ASP	158	−39.519	−1.966	6.245
ATOM	858	O	ASP	158	−39.89	−1.123	7.047
ATOM	859	CB	ASP	158	−38.755	−0.891	4.042
ATOM	860	CG	ASP	158	−37.56	−0.291	3.33
ATOM	861	OD1	ASP	158	−36.605	0.159	4.026
ATOM	862	OD2	ASP	158	−37.565	−0.24	2.068
ATOM	863	HA	ASP	158	−37.707	−0.937	5.923
ATOM	864	H	ASP	158	−37.516	−3.146	4.101
ATOM	865	HB1	ASP	158	−39.288	−1.588	3.379
ATOM	866	HB2	ASP	158	−39.438	−0.07	4.293
ATOM	867	N	LEU	159	−40.125	−3.175	6.189
ATOM	868	CA	LEU	159	−41.112	−3.518	7.215
ATOM	869	C	LEU	159	−40.446	−3.579	8.57
ATOM	870	O	LEU	159	−40.995	−3.027	9.511
ATOM	871	CB	LEU	159	−41.849	−4.875	7.016
ATOM	872	CG	LEU	159	−42.995	−4.897	5.962
ATOM	873	CD1	LEU	159	−43.721	−6.27	6.053
ATOM	874	CD2	LEU	159	−44.042	−3.769	6.181
ATOM	875	HA	LEU	159	−41.835	−2.696	7.303
ATOM	876	H	LEU	159	−39.865	−3.862	5.508
ATOM	877	HB1	LEU	159	−41.108	−5.653	6.783
ATOM	878	HB2	LEU	159	−42.315	−5.154	7.97
ATOM	879	HG	LEU	159	−42.556	−4.787	4.957
ATOM	880	HD21	LEU	159	−43.618	−2.775	6.002
ATOM	881	HD22	LEU	159	−44.873	−3.884	5.474
ATOM	882	HD23	LEU	159	−44.444	−3.801	7.205
ATOM	883	HD11	LEU	159	−44.187	−6.402	7.042
ATOM	884	HD12	LEU	159	−44.519	−6.341	5.302
ATOM	885	HD13	LEU	159	−43.012	−7.096	5.892
ATOM	886	N	LEU	160	−39.274	−4.225	8.732
ATOM	887	CA	LEU	160	−38.667	−4.262	10.064
ATOM	888	C	LEU	160	−38.485	−2.845	10.574
ATOM	889	O	LEU	160	−38.683	−2.608	11.756
ATOM	890	CB	LEU	160	−37.326	−5.046	10.075
ATOM	891	CG	LEU	160	−37.479	−6.569	9.761
ATOM	892	CD1	LEU	160	−36.088	−7.187	9.45
ATOM	893	CD2	LEU	160	−38.147	−7.353	10.927
ATOM	894	HA	LEU	160	−39.377	−4.746	10.752
ATOM	895	H	LEU	160	−38.809	−4.64	7.946
ATOM	896	HB1	LEU	160	−36.663	−4.571	9.334
ATOM	897	HB2	LEU	160	−36.852	−4.936	11.063
ATOM	898	HG	LEU	160	−38.102	−6.711	8.862
ATOM	899	HD21	LEU	160	−39.184	−7.031	11.097
ATOM	900	HD22	LEU	160	−38.173	−8.429	10.697
ATOM	901	HD23	LEU	160	−37.578	−7.214	11.859
ATOM	902	HD11	LEU	160	−35.407	−7.052	10.304
ATOM	903	HD12	LEU	160	−36.173	−8.263	9.232
ATOM	904	HD13	LEU	160	−35.65	−6.699	8.566
ATOM	905	N	PHE	161	−38.139	−1.877	9.696
ATOM	906	CA	PHE	161	−38.089	−0.473	10.123
ATOM	907	C	PHE	161	−39.423	0.039	10.629
ATOM	908	O	PHE	161	−39.405	0.954	11.436
ATOM	909	CB	PHE	161	−37.521	0.401	8.968
ATOM	910	CG	PHE	161	−37.397	1.892	9.319
ATOM	911	CD1	PHE	161	−36.313	2.365	10.064
ATOM	912	CD2	PHE	161	−38.357	2.807	8.877
ATOM	913	CE1	PHE	161	−36.221	3.72	10.391
ATOM	914	CE2	PHE	161	−38.283	4.16	9.215
ATOM	915	CZ	PHE	161	−37.216	4.614	9.991
ATOM	916	HA	PHE	161	−37.423	−0.393	10.99
ATOM	917	H	PHE	161	−37.951	−2.107	8.736
ATOM	918	HB1	PHE	161	−36.524	0.026	8.684
ATOM	919	HB2	PHE	161	−38.171	0.3	8.09
ATOM	920	HD2	PHE	161	−39.169	2.469	8.253
ATOM	921	HE2	PHE	161	−39.047	4.853	8.877
ATOM	922	HZ	PHE	161	−37.158	5.654	10.282
ATOM	923	HE1	PHE	161	−35.375	4.084	10.958
ATOM	924	HD1	PHE	161	−35.535	1.685	10.383
ATOM	925	N	LEU	162	−40.579	−0.515	10.193
ATOM	926	CA	LEU	162	−41.886	−0.006	10.619
ATOM	927	C	LEU	162	−42.744	−0.953	11.434
ATOM	928	O	LEU	162	−43.766	−0.48	11.903
ATOM	929	CB	LEU	162	−42.679	0.381	9.344
ATOM	930	CG	LEU	162	−41.919	1.398	8.449
ATOM	931	CD1	LEU	162	−42.656	1.592	7.097
ATOM	932	CD2	LEU	162	−41.716	2.753	9.187
ATOM	933	HA	LEU	162	−41.788	0.886	11.255
ATOM	934	H	LEU	162	−40.565	−1.253	9.521
ATOM	935	HB1	LEU	162	−42.87	−0.54	8.771
ATOM	936	HB2	LEU	162	−43.646	0.818	9.638
ATOM	937	HG	LEU	162	−40.937	0.97	8.193
ATOM	938	HD21	LEU	162	−40.958	2.659	9.978
ATOM	939	HD22	LEU	162	−41.377	3.534	8.491
ATOM	940	HD23	LEU	162	−42.647	3.094	9.657
ATOM	941	HD11	LEU	162	−43.668	1.985	7.253
ATOM	942	HD12	LEU	162	−42.092	2.297	6.467
ATOM	943	HD13	LEU	162	−42.736	0.635	6.556
ATOM	944	N	LEU	163	−42.429	−2.251	11.645
ATOM	945	CA	LEU	163	−43.296	−3.068	12.503
ATOM	946	C	LEU	163	−42.974	−2.811	13.958
ATOM	947	O	LEU	163	−43.889	−2.62	14.744
ATOM	948	CB	LEU	163	−43.173	−4.596	12.252
ATOM	949	CG	LEU	163	−43.53	−5.03	10.801
ATOM	950	CD1	LEU	163	−43.334	−6.565	10.651
ATOM	951	CD2	LEU	163	−44.967	−4.626	10.368
ATOM	952	HA	LEU	163	−44.353	−2.792	12.358
ATOM	953	H	LEU	163	−41.597	−2.653	11.257
ATOM	954	HB1	LEU	163	−42.136	−4.901	12.472
ATOM	955	HB2	LEU	163	−43.837	−5.127	12.954
ATOM	956	HG	LEU	163	−42.827	−4.528	10.126
ATOM	957	HD21	LEU	163	−45.062	−3.535	10.258
ATOM	958	HD22	LEU	163	−45.213	−5.074	9.393
ATOM	959	HD23	LEU	163	−45.702	−4.977	11.108
ATOM	960	HD11	LEU	163	−44.032	−7.104	11.31
ATOM	961	HD12	LEU	163	−43.519	−6.884	9.613
ATOM	962	HD13	LEU	163	−42.305	−6.854	10.917
ATOM	963	N	GLY	164	−41.682	−2.814	14.353
ATOM	964	CA	GLY	164	−41.355	−2.581	15.758
ATOM	965	C	GLY	164	−41.366	−1.11	16.102
ATOM	966	O	GLY	164	−41.744	−0.783	17.216
ATOM	967	HA2	GLY	164	−40.357	−2.985	15.985
ATOM	968	HA1	GLY	164	−42.069	−3.112	16.409
ATOM	969	H	GLY	164	−40.933	−2.958	13.7
ATOM	970	N	MET	165	−40.933	−0.202	15.193
ATOM	971	CA	MET	165	−40.866	1.213	15.56
ATOM	972	C	MET	165	−42.148	1.685	16.221
ATOM	973	O	MET	165	−42.028	2.217	17.312
ATOM	974	CB	MET	165	−40.454	2.174	14.405
ATOM	975	CG	MET	165	−38.929	2.438	14.313
ATOM	976	SD	MET	165	−38.675	3.643	12.963
ATOM	977	CE	MET	165	−37.057	4.334	13.409
ATOM	978	HA	MET	165	−40.084	1.291	16.333
ATOM	979	H	MET	165	−40.609	−0.482	14.288
ATOM	980	HB1	MET	165	−40.781	1.783	13.433
ATOM	981	HB2	MET	165	−40.942	3.148	14.564
ATOM	982	HG1	MET	165	−38.373	1.513	14.095
ATOM	983	HG2	MET	165	−38.562	2.866	15.259
ATOM	984	LPD1	MET	165	−38.656	3.338	12.357
ATOM	985	LPD2	MET	165	−39.157	4.121	12.961
ATOM	986	HE1	MET	165	−36.284	3.559	13.309
ATOM	987	HE2	MET	165	−36.817	5.188	12.76
ATOM	988	HE3	MET	165	−37.097	4.691	14.443
ATOM	989	N	PRO	166	−43.38	1.541	15.677
ATOM	990	CA	PRO	166	−44.554	1.983	16.414
ATOM	991	C	PRO	166	−44.574	1.539	17.855
ATOM	992	O	PRO	166	−44.943	2.335	18.701
ATOM	993	CB	PRO	166	−45.67	1.291	15.597
ATOM	994	CG	PRO	166	−45.094	1.289	14.165
ATOM	995	CD	PRO	166	−43.604	0.93	14.378
ATOM	996	HA	PRO	166	−44.63	3.081	16.335
ATOM	997	HD2	PRO	166	−43	1.345	13.564
ATOM	998	HD1	PRO	166	−43.465	−0.156	14.45
ATOM	999	HG2	PRO	166	−45.165	2.314	13.767
ATOM	1000	HG1	PRO	166	−45.619	0.6	13.483
ATOM	1001	HB1	PRO	166	−46.641	1.807	15.677
ATOM	1002	HB2	PRO	166	−45.795	0.244	15.922
ATOM	1003	N	PHE	167	−44.18	0.289	18.178
ATOM	1004	CA	PHE	167	−44.225	−0.127	19.579
ATOM	1005	C	PHE	167	−43.36	0.793	20.412
ATOM	1006	O	PHE	167	−43.784	1.214	21.476
ATOM	1007	CB	PHE	167	−43.743	−1.59	19.762
ATOM	1008	CG	PHE	167	−43.93	−2.024	21.224
ATOM	1009	CD1	PHE	167	−45.112	−2.652	21.631
ATOM	1010	CD2	PHE	167	−42.919	−1.795	22.164
ATOM	1011	CE1	PHE	167	−45.275	−3.06	22.958
ATOM	1012	CE2	PHE	167	−43.081	−2.195	23.493
ATOM	1013	CZ	PHE	167	−44.26	−2.832	23.891
ATOM	1014	HA	PHE	167	−45.269	−0.059	19.93
ATOM	1015	H	PHE	167	−43.836	−0.345	17.481
ATOM	1016	HB1	PHE	167	−44.323	−2.254	19.102
ATOM	1017	HB2	PHE	167	−42.684	−1.682	19.479
ATOM	1018	HD2	PHE	167	−42.001	−1.303	21.865
ATOM	1019	HE2	PHE	167	−42.292	−2.011	24.216
ATOM	1020	HZ	PHE	167	−44.386	−3.148	24.922
ATOM	1021	HE1	PHE	167	−46.192	−3.555	23.265
ATOM	1022	HD1	PHE	167	−45.911	−2.827	20.918
ATOM	1023	N	MET	168	−42.133	1.109	19.939
ATOM	1024	CA	MET	168	−41.23	1.944	20.73
ATOM	1025	C	MET	168	−41.489	3.412	20.475
ATOM	1026	O	MET	168	−41.676	4.147	21.43
ATOM	1027	CB	MET	168	−39.756	1.545	20.45
ATOM	1028	CG	MET	168	−39.495	0.09	20.925
ATOM	1029	SD	MET	168	−37.715	−0.277	20.907
ATOM	1030	CE	MET	168	−37.748	−2.034	21.382
ATOM	1031	HA	MET	168	−41.406	1.773	21.806
ATOM	1032	H	MET	168	−41.837	0.798	19.031
ATOM	1033	HB1	MET	168	−39.524	1.648	19.379
ATOM	1034	HB2	MET	168	−39.09	2.224	20.999
ATOM	1035	HG1	MET	168	−39.824	−0.043	21.967
ATOM	1036	HG2	MET	168	−40.026	−0.629	20.282
ATOM	1037	LPD1	MET	168	−37.446	−0.188	20.29
ATOM	1038	LPD2	MET	168	−37.376	0.099	21.359
ATOM	1039	HE1	MET	168	−38.216	−2.63	20.586
ATOM	1040	HE2	MET	168	−36.716	−2.382	21.534
ATOM	1041	HE3	MET	168	−38.32	−2.165	22.311
ATOM	1042	N	ILE	169	−41.527	3.892	19.214
ATOM	1043	CA	ILE	169	−41.855	5.299	18.98
ATOM	1044	C	ILE	169	−43.169	5.627	19.66
ATOM	1045	O	ILE	169	−43.288	6.728	20.175
ATOM	1046	CB	ILE	169	−41.852	5.694	17.466
ATOM	1047	CG1	ILE	169	−40.391	5.656	16.91
ATOM	1048	CG2	ILE	169	−42.504	7.092	17.252
ATOM	1049	CD1	ILE	169	−40.253	6.096	15.427
ATOM	1050	HA	ILE	169	−41.089	5.909	19.487
ATOM	1051	H	ILE	169	−41.376	3.283	18.438
ATOM	1052	HB	ILE	169	−42.468	4.962	16.916
ATOM	1053	HG11	ILE	169	−39.739	6.308	17.514
ATOM	1054	HG12	ILE	169	−40.004	4.627	16.993
ATOM	1055	HD11	ILE	169	−40.391	7.181	15.31
ATOM	1056	HD12	ILE	169	−39.245	5.854	15.057
ATOM	1057	HD13	ILE	169	−40.988	5.575	14.801
ATOM	1058	HG21	ILE	169	−41.935	7.866	17.79
ATOM	1059	HG22	ILE	169	−42.549	7.359	16.187
ATOM	1060	HG23	ILE	169	−43.543	7.101	17.614
ATOM	1061	N	HIS	170	−44.178	4.728	19.718
ATOM	1062	CA	HIS	170	−45.396	5.1	20.437
ATOM	1063	C	HIS	170	−45.065	5.439	21.874
ATOM	1064	O	HIS	170	−45.715	6.319	22.412
ATOM	1065	CB	HIS	170	−46.54	4.056	20.402
ATOM	1066	CG	HIS	170	−47.788	4.65	21.01
ATOM	1067	ND1	HIS	170	−47.975	4.828	22.299
ATOM	1068	CD2	HIS	170	−48.866	5.085	20.326
ATOM	1069	CE1	HIS	170	−49.134	5.369	22.502
ATOM	1070	NE2	HIS	170	−49.705	5.544	21.399
ATOM	1071	HA	HIS	170	−45.785	6.003	19.94
ATOM	1072	H	HIS	170	−44.11	3.819	19.303
ATOM	1073	HB1	HIS	170	−46.765	3.804	19.354
ATOM	1074	HB2	HIS	170	−46.249	3.138	20.936
ATOM	1075	HD2	HIS	170	−49.057	5.094	19.253
ATOM	1076	HE1	HIS	170	−49.563	5.638	23.467
ATOM	1077	HD1	HIS	170	−47.301	4.584	23.039
ATOM	1078	N	GLN	171	−44.072	4.796	22.533
ATOM	1079	CA	GLN	171	−43.689	5.258	23.87
ATOM	1080	C	GLN	171	−43.352	6.73	23.775
ATOM	1081	O	GLN	171	−43.778	7.496	24.623
ATOM	1082	CB	GLN	171	−42.451	4.535	24.476
ATOM	1083	CG	GLN	171	−42.7	3.044	24.824
ATOM	1084	CD	GLN	171	−43.599	2.937	26.033
ATOM	1085	OE1	GLN	171	−43.09	2.998	27.142
ATOM	1086	NE2	GLN	171	−44.93	2.792	25.869
ATOM	1087	HA	GLN	171	−44.549	5.142	24.547
ATOM	1088	H	GLN	171	−43.549	4.061	22.099
ATOM	1089	HB1	GLN	171	−41.598	4.617	23.788
ATOM	1090	HB2	GLN	171	−42.158	5.047	25.405
ATOM	1091	HG1	GLN	171	−43.121	2.502	23.963
ATOM	1092	HG2	GLN	171	−41.738	2.566	25.075
ATOM	1093	HE22	GLN	171	−45.514	2.739	26.68
ATOM	1094	HE21	GLN	171	−45.348	2.735	24.962
ATOM	1095	N	LEU	172	−42.594	7.16	22.743
ATOM	1096	CA	LEU	172	−42.293	8.584	22.623
ATOM	1097	C	LEU	172	−43.585	9.363	22.533
ATOM	1098	O	LEU	172	−43.731	10.365	23.213
ATOM	1099	CB	LEU	172	−41.448	8.923	21.357
ATOM	1100	CG	LEU	172	−40.783	10.329	21.444
ATOM	1101	CD1	LEU	172	−39.5	10.286	22.321
ATOM	1102	CD2	LEU	172	−40.433	10.862	20.027
ATOM	1103	HA	LEU	172	−41.761	8.88	23.54
ATOM	1104	H	LEU	172	−42.264	6.526	22.041
ATOM	1105	HB1	LEU	172	−42.107	8.887	20.477
ATOM	1106	HB2	LEU	172	−40.661	8.172	21.196
ATOM	1107	HG	LEU	172	−41.5	11.04	21.89
ATOM	1108	HD21	LEU	172	−41.334	10.924	19.397
ATOM	1109	HD22	LEU	172	−40.007	11.874	20.102
ATOM	1110	HD23	LEU	172	−39.705	10.199	19.535
ATOM	1111	HD11	LEU	172	−38.737	9.643	21.856
ATOM	1112	HD12	LEU	172	−39.085	11.297	22.429
ATOM	1113	HD13	LEU	172	−39.703	9.896	23.327
ATOM	1114	N	MET	173	−44.536	8.918	21.683
ATOM	1115	CA	MET	173	−45.762	9.691	21.487
ATOM	1116	C	MET	173	−46.577	9.735	22.762
ATOM	1117	O	MET	173	−47.031	10.804	23.139
ATOM	1118	CB	MET	173	−46.642	9.093	20.353
ATOM	1119	CG	MET	173	−45.952	9.186	18.964
ATOM	1120	SD	MET	173	−46.861	8.152	17.768
ATOM	1121	CE	MET	173	−46.108	8.663	16.189
ATOM	1122	HA	MET	173	−45.491	10.723	21.206
ATOM	1123	H	MET	173	−44.406	8.056	21.187
ATOM	1124	HB1	MET	173	−46.87	8.045	20.598
ATOM	1125	HB2	MET	173	−47.601	9.635	20.301
ATOM	1126	HG1	MET	173	−45.942	10.232	18.624
ATOM	1127	HG2	MET	173	−44.916	8.819	18.995
ATOM	1128	LPD1	MET	173	−46.762	7.491	17.887
ATOM	1129	LPD2	MET	173	−47.527	8.286	17.78
ATOM	1130	HE1	MET	173	−46.327	7.904	15.424
ATOM	1131	HE2	MET	173	−46.545	9.621	15.873
ATOM	1132	HE3	MET	173	−45.019	8.772	16.289
ATOM	1133	N	GLY	174	−46.794	8.584	23.434
ATOM	1134	CA	GLY	174	−47.64	8.578	24.624
ATOM	1135	C	GLY	174	−46.914	9.117	25.831
ATOM	1136	O	GLY	174	−47.457	9.965	26.521
ATOM	1137	HA2	GLY	174	−47.955	7.55	24.866
ATOM	1138	HA1	GLY	174	−48.554	9.166	24.44
ATOM	1139	H	GLY	174	−46.381	7.723	23.131
ATOM	1140	N	ASN	175	−45.691	8.624	26.127
ATOM	1141	CA	ASN	175	−44.987	9.093	27.32
ATOM	1142	C	ASN	175	−44.405	10.47	27.092
ATOM	1143	O	ASN	175	−44.528	11.303	27.975
ATOM	1144	CB	ASN	175	−43.839	8.135	27.719
ATOM	1145	CG	ASN	175	−44.364	6.73	27.888
ATOM	1146	OD1	ASN	175	−44.158	5.909	27.009
ATOM	1147	ND2	ASN	175	−45.053	6.412	29.002
ATOM	1148	HA	ASN	175	−45.697	9.137	28.164
ATOM	1149	H	ASN	175	−45.249	7.947	25.533
ATOM	1150	HB1	ASN	175	−43.064	8.156	26.939
ATOM	1151	HB2	ASN	175	−43.382	8.476	28.661
ATOM	1152	HD22	ASN	175	−45.404	5.481	29.107
ATOM	1153	HD21	ASN	175	−45.21	7.077	29.732
ATOM	1154	N	GLY	176	−43.762	10.726	25.928
ATOM	1155	CA	GLY	176	−43.219	12.055	25.644
ATOM	1156	C	GLY	176	−41.748	11.997	25.307
ATOM	1157	O	GLY	176	−41.376	12.438	24.232
ATOM	1158	HA2	GLY	176	−43.317	12.752	26.49
ATOM	1159	HA1	GLY	176	−43.778	12.489	24.799
ATOM	1160	H	GLY	176	−43.676	10.032	25.208
ATOM	1161	N	VAL	177	−40.891	11.484	26.223
ATOM	1162	CA	VAL	177	−39.442	11.528	26.002
ATOM	1163	C	VAL	177	−38.798	10.237	26.469
ATOM	1164	O	VAL	177	−39.262	9.714	27.469
ATOM	1165	CB	VAL	177	−38.819	12.736	26.762
ATOM	1166	CG1	VAL	177	−37.279	12.809	26.555
ATOM	1167	CG2	VAL	177	−39.473	14.072	26.312
ATOM	1168	HA	VAL	177	−39.22	11.671	24.936
ATOM	1169	H	VAL	177	−41.221	11.118	27.096
ATOM	1170	HB	VAL	177	−39.017	12.604	27.84
ATOM	1171	HG11	VAL	177	−37.035	12.884	25.484
ATOM	1172	HG12	VAL	177	−36.862	13.688	27.069
ATOM	1173	HG13	VAL	177	−36.785	11.918	26.969
ATOM	1174	HG21	VAL	177	−40.55	14.078	26.538
ATOM	1175	HG22	VAL	177	−39.016	14.923	26.84
ATOM	1176	HG23	VAL	177	−39.338	14.22	25.229
ATOM	1177	N	TRP	178	−37.746	9.738	25.77
ATOM	1178	CA	TRP	178	−36.988	8.552	26.191
ATOM	1179	C	TRP	178	−37.562	7.753	27.342
ATOM	1180	O	TRP	178	−36.96	7.706	28.403
ATOM	1181	CB	TRP	178	−35.51	8.963	26.455
ATOM	1182	CG	TRP	178	−34.923	9.511	25.181
ATOM	1183	CD1	TRP	178	−34.483	10.753	24.913
ATOM	1184	CD2	TRP	178	−34.756	8.708	23.918
ATOM	1185	NE1	TRP	178	−34.109	10.819	23.659
ATOM	1186	CE2	TRP	178	−34.286	9.645	23.022
ATOM	1187	CE3	TRP	178	−34.972	7.379	23.566
ATOM	1188	CZ2	TRP	178	−34.076	9.32	21.682
ATOM	1189	CZ3	TRP	178	−34.859	7.067	22.208
ATOM	1190	CH2	TRP	178	−34.464	8.037	21.274
ATOM	1191	HA	TRP	178	−36.998	7.849	25.347
ATOM	1192	H	TRP	178	−37.433	10.195	24.935
ATOM	1193	HB1	TRP	178	−35.472	9.712	27.261
ATOM	1194	HB2	TRP	178	−34.913	8.089	26.758
ATOM	1195	HE1	TRP	178	−33.745	11.671	23.207
ATOM	1196	HD1	TRP	178	−34.455	11.576	25.628
ATOM	1197	HZ2	TRP	178	−33.638	10.027	20.99
ATOM	1198	HH2	TRP	178	−34.462	7.794	20.218
ATOM	1199	HZ3	TRP	178	−35.082	6.06	21.88
ATOM	1200	HE3	TRP	178	−35.213	6.634	24.313
ATOM	1201	N	HIS	179	−38.729	7.1	27.135
ATOM	1202	CA	HIS	179	−39.367	6.333	28.209
ATOM	1203	C	HIS	179	−39.061	4.852	28.129
ATOM	1204	O	HIS	179	−39.805	4.074	28.701
ATOM	1205	CB	HIS	179	−40.883	6.66	28.17
ATOM	1206	CG	HIS	179	−41.713	5.993	29.236
ATOM	1207	ND1	HIS	179	−42.265	4.807	29.103
ATOM	1208	CD2	HIS	179	−42.012	6.508	30.445
ATOM	1209	CE1	HIS	179	−42.918	4.508	30.179
ATOM	1210	NE2	HIS	179	−42.816	5.451	31
ATOM	1211	HA	HIS	179	−39.008	6.655	29.201
ATOM	1212	H	HIS	179	−39.18	7.136	26.241
ATOM	1213	HB1	HIS	179	−40.977	7.752	28.284
ATOM	1214	HB2	HIS	179	−41.296	6.384	27.191
ATOM	1215	HD2	HIS	179	−41.727	7.461	30.886
ATOM	1216	HE1	HIS	179	−43.475	3.587	30.354
ATOM	1217	HD1	HIS	179	−42.191	4.202	28.268
ATOM	1218	N	PHE	180	−37.971	4.403	27.463
ATOM	1219	CA	PHE	180	−37.626	2.98	27.515
ATOM	1220	C	PHE	180	−36.135	2.774	27.311
ATOM	1221	O	PHE	180	−35.715	1.921	26.546
ATOM	1222	CB	PHE	180	−38.579	2.173	26.587
ATOM	1223	CG	PHE	180	−38.141	0.707	26.46
ATOM	1224	CD1	PHE	180	−38.183	−0.132	27.579
ATOM	1225	CD2	PHE	180	−37.693	0.194	25.237
ATOM	1226	CE1	PHE	180	−37.719	−1.448	27.496
ATOM	1227	CE2	PHE	180	−37.223	−1.12	25.154
ATOM	1228	CZ	PHE	180	−37.229	−1.941	26.284
ATOM	1229	HA	PHE	180	−37.777	2.61	28.543
ATOM	1230	H	PHE	180	−37.382	5.018	26.935
ATOM	1231	HB1	PHE	180	−39.601	2.182	26.997
ATOM	1232	HB2	PHE	180	−38.635	2.659	25.603
ATOM	1233	HD2	PHE	180	−37.704	0.809	24.345
ATOM	1234	HE2	PHE	180	−36.852	−1.501	24.21
ATOM	1235	HZ	PHE	180	−36.855	−2.958	26.22
ATOM	1236	HE1	PHE	180	−37.741	−2.088	28.373
ATOM	1237	HD1	PHE	180	−38.575	0.235	28.522
ATOM	1238	N	GLY	181	−35.302	3.558	28.038
ATOM	1239	CA	GLY	181	−33.855	3.336	28.01
ATOM	1240	C	GLY	181	−33.218	3.534	26.656
ATOM	1241	O	GLY	181	−33.903	3.834	25.692
ATOM	1242	HA2	GLY	181	−33.652	2.304	28.333
ATOM	1243	HA1	GLY	181	−33.349	4.017	28.714
ATOM	1244	H	GLY	181	−35.66	4.266	28.652
ATOM	1245	N	GLU	182	−31.88	3.35	26.558
ATOM	1246	CA	GLU	182	−31.237	3.4	25.245
ATOM	1247	C	GLU	182	−31.673	2.208	24.418
ATOM	1248	O	GLU	182	−31.503	2.256	23.211
ATOM	1249	CB	GLU	182	−29.688	3.512	25.338
ATOM	1250	CG	GLU	182	−29.271	4.885	25.933
ATOM	1251	CD	GLU	182	−27.786	4.964	26.168
ATOM	1252	OE1	GLU	182	−27.023	5.342	25.234
ATOM	1253	OE2	GLU	182	−27.338	4.671	27.311
ATOM	1254	HA	GLU	182	−31.592	4.3	24.716
ATOM	1255	H	GLU	182	−31.329	3.105	27.358
ATOM	1256	HB1	GLU	182	−29.299	2.691	25.961
ATOM	1257	HB2	GLU	182	−29.244	3.419	24.333
ATOM	1258	HG1	GLU	182	−29.563	5.698	25.249
ATOM	1259	HG2	GLU	182	−29.78	5.053	26.895
ATOM	1260	N	THR	183	−32.263	1.134	24.995
ATOM	1261	CA	THR	183	−32.852	0.096	24.149
ATOM	1262	C	THR	183	−33.861	0.727	23.207
ATOM	1263	O	THR	183	−33.923	0.363	22.043
ATOM	1264	CB	THR	183	−33.545	−0.997	25.006
ATOM	1265	OG1	THR	183	−32.624	−1.38	26.043
ATOM	1266	CG2	THR	183	−33.917	−2.232	24.142
ATOM	1267	HA	THR	183	−32.028	−0.377	23.596
ATOM	1268	H	THR	183	−32.345	1.031	25.987
ATOM	1269	HB	THR	183	−34.451	−0.564	25.467
ATOM	1270	HG1	THR	183	−32.982	−2.034	26.635
ATOM	1271	HG23	THR	183	−34.558	−1.944	23.295
ATOM	1272	HG21	THR	183	−33.004	−2.702	23.745
ATOM	1273	HG22	THR	183	−34.455	−2.973	24.752
ATOM	1274	N	MET	184	−34.66	1.703	23.69
ATOM	1275	CA	MET	184	−35.57	2.427	22.795
ATOM	1276	C	MET	184	−34.797	3.041	21.643
ATOM	1277	O	MET	184	−35.201	2.935	20.495
ATOM	1278	CB	MET	184	−36.26	3.566	23.597
ATOM	1279	CG	MET	184	−37.447	4.235	22.869
ATOM	1280	SD	MET	184	−38.071	5.547	23.968
ATOM	1281	CE	MET	184	−39.095	6.483	22.801
ATOM	1282	HA	MET	184	−36.328	1.73	22.409
ATOM	1283	H	MET	184	−34.614	1.961	24.661
ATOM	1284	HB1	MET	184	−36.642	3.162	24.541
ATOM	1285	HB2	MET	184	−35.517	4.333	23.846
ATOM	1286	HG1	MET	184	−37.141	4.649	21.896
ATOM	1287	HG2	MET	184	−38.263	3.516	22.724
ATOM	1288	LPD1	MET	184	−38.44	5.293	24.478
ATOM	1289	LPD2	MET	184	−37.567	5.925	24.219
ATOM	1290	HE1	MET	184	−39.785	5.805	22.279
ATOM	1291	HE2	MET	184	−39.667	7.231	23.367
ATOM	1292	HE3	MET	184	−38.448	6.986	22.068
ATOM	1293	N	CYS	185	−33.662	3.699	21.963
ATOM	1294	CA	CYS	185	−32.825	4.329	20.938
ATOM	1295	C	CYS	185	−32.197	3.266	20.058
ATOM	1296	O	CYS	185	−31.971	3.516	18.884
ATOM	1297	CB	CYS	185	−31.773	5.2	21.683
ATOM	1298	SG	CYS	185	−30.765	6.383	20.746
ATOM	1299	HA	CYS	185	−33.454	4.982	20.317
ATOM	1300	H	CYS	185	−33.361	3.723	22.918
ATOM	1301	HB1	CYS	185	−32.292	5.828	22.424
ATOM	1302	HB2	CYS	185	−31.059	4.554	22.214
ATOM	1303	LPG1	CYS	185	−30.547	6.88	21.153
ATOM	1304	LPG2	CYS	185	−30.232	6.068	20.467
ATOM	1305	N	THR	186	−31.914	2.061	20.605
ATOM	1306	CA	THR	186	−31.334	0.992	19.795
ATOM	1307	C	THR	186	−32.239	0.618	18.654
ATOM	1308	O	THR	186	−31.791	0.687	17.522
ATOM	1309	CB	THR	186	−30.986	−0.287	20.614
ATOM	1310	OG1	THR	186	−29.827	−0.036	21.429
ATOM	1311	CG2	THR	186	−30.742	−1.549	19.74
ATOM	1312	HA	THR	186	−30.403	1.384	19.369
ATOM	1313	H	THR	186	−32.086	1.882	21.574
ATOM	1314	HB	THR	186	−31.833	−0.557	21.259
ATOM	1315	HG1	THR	186	−29.94	0.691	22.034
ATOM	1316	HG23	THR	186	−31.671	−1.88	19.25
ATOM	1317	HG21	THR	186	−29.995	−1.37	18.957
ATOM	1318	HG22	THR	186	−30.385	−2.373	20.376
ATOM	1319	N	LEU	187	−33.498	0.199	18.898
ATOM	1320	CA	LEU	187	−34.321	−0.227	17.766
ATOM	1321	C	LEU	187	−34.403	0.902	16.764
ATOM	1322	O	LEU	187	−34.232	0.67	15.576
ATOM	1323	CB	LEU	187	−35.764	−0.596	18.203
ATOM	1324	CG	LEU	187	−36.67	−1.068	17.025
ATOM	1325	CD1	LEU	187	−36.326	−2.513	16.564
ATOM	1326	CD2	LEU	187	−38.165	−0.998	17.435
ATOM	1327	HA	LEU	187	−33.831	−1.097	17.303
ATOM	1328	H	LEU	187	−33.864	0.167	19.833
ATOM	1329	HB1	LEU	187	−35.73	−1.377	18.978
ATOM	1330	HB2	LEU	187	−36.195	0.312	18.651
ATOM	1331	HG	LEU	187	−36.552	−0.386	16.166
ATOM	1332	HD21	LEU	187	−38.436	0.013	17.773
ATOM	1333	HD22	LEU	187	−38.781	−1.241	16.561
ATOM	1334	HD23	LEU	187	−38.39	−1.712	18.239
ATOM	1335	HD11	LEU	187	−35.284	−2.597	16.229
ATOM	1336	HD12	LEU	187	−36.975	−2.809	15.724
ATOM	1337	HD13	LEU	187	−36.481	−3.224	17.39
ATOM	1338	N	ILE	188	−34.671	2.135	17.251
ATOM	1339	CA	ILE	188	−34.8	3.275	16.343
ATOM	1340	C	ILE	188	−33.593	3.335	15.433
ATOM	1341	O	ILE	188	−33.751	3.575	14.246
ATOM	1342	CB	ILE	188	−34.985	4.611	17.139
ATOM	1343	CG1	ILE	188	−36.432	4.677	17.728
ATOM	1344	CG2	ILE	188	−34.648	5.873	16.288
ATOM	1345	CD1	ILE	188	−36.638	5.79	18.79
ATOM	1346	HA	ILE	188	−35.685	3.102	15.713
ATOM	1347	H	ILE	188	−34.77	2.281	18.238
ATOM	1348	HB	ILE	188	−34.257	4.604	17.966
ATOM	1349	HG11	ILE	188	−37.161	4.826	16.917
ATOM	1350	HG12	ILE	188	−36.677	3.72	18.217
ATOM	1351	HD11	ILE	188	−36.56	6.796	18.353
ATOM	1352	HD12	ILE	188	−37.638	5.697	19.245
ATOM	1353	HD13	ILE	188	−35.888	5.685	19.585
ATOM	1354	HG21	ILE	188	−35.327	5.961	15.431
ATOM	1355	HG22	ILE	188	−34.726	6.789	16.89
ATOM	1356	HG23	ILE	188	−33.617	5.836	15.907
ATOM	1357	N	THR	189	−32.373	3.132	15.973
ATOM	1358	CA	THR	189	−31.177	3.314	15.151
ATOM	1359	C	THR	189	−30.861	2.059	14.377
ATOM	1360	O	THR	189	−30.63	2.135	13.182
ATOM	1361	CB	THR	189	−29.898	3.621	15.979
ATOM	1362	OG1	THR	189	−30.137	4.527	17.058
ATOM	1363	CG2	THR	189	−28.795	4.268	15.099
ATOM	1364	HA	THR	189	−31.346	4.161	14.467
ATOM	1365	H	THR	189	−32.284	2.845	16.928
ATOM	1366	HB	THR	189	−29.522	2.686	16.419
ATOM	1367	HG1	THR	189	−30.695	4.195	17.756
ATOM	1368	HG23	THR	189	−28.474	3.581	14.301
ATOM	1369	HG21	THR	189	−29.163	5.199	14.641
ATOM	1370	HG22	THR	189	−27.924	4.525	15.722
ATOM	1371	N	ALA	190	−30.815	0.895	15.064
ATOM	1372	CA	ALA	190	−30.397	−0.339	14.412
ATOM	1373	C	ALA	190	−31.162	−0.517	13.129
ATOM	1374	O	ALA	190	−30.562	−0.895	12.136
ATOM	1375	CB	ALA	190	−30.658	−1.568	15.323
ATOM	1376	HA	ALA	190	−29.318	−0.272	14.189
ATOM	1377	H	ALA	190	−31.035	0.861	16.038
ATOM	1378	HB1	ALA	190	−30.367	−2.497	14.81
ATOM	1379	HB2	ALA	190	−30.071	−1.482	16.251
ATOM	1380	HB3	ALA	190	−31.726	−1.628	15.585
ATOM	1381	N	MET	191	−32.485	−0.245	13.121
ATOM	1382	CA	MET	191	−33.23	−0.409	11.879
ATOM	1383	C	MET	191	−32.912	0.72	10.92
ATOM	1384	O	MET	191	−32.69	0.441	9.752
ATOM	1385	CB	MET	191	−34.757	−0.495	12.108
ATOM	1386	CG	MET	191	−35.195	−1.644	13.055
ATOM	1387	SD	MET	191	−34.768	−3.273	12.352
ATOM	1388	CE	MET	191	−33.318	−3.752	13.344
ATOM	1389	HA	MET	191	−32.929	−1.354	11.403
ATOM	1390	H	MET	191	−32.956	0.106	13.936
ATOM	1391	HB1	MET	191	−35.126	0.462	12.514
ATOM	1392	HB2	MET	191	−35.199	−0.668	11.116
ATOM	1393	HG1	MET	191	−34.748	−1.528	14.052
ATOM	1394	HG2	MET	191	−36.29	−1.622	13.167
ATOM	1395	LPD1	MET	191	−35.277	−3.716	12.43
ATOM	1396	LPD2	MET	191	−34.61	−3.223	11.693
ATOM	1397	HE1	MET	191	−33.595	−3.815	14.407
ATOM	1398	HE2	MET	191	−32.966	−4.737	13.005
ATOM	1399	HE3	MET	191	−32.507	−3.022	13.221
ATOM	1400	N	ASP	192	−32.885	1.994	11.379
ATOM	1401	CA	ASP	192	−32.549	3.099	10.472
ATOM	1402	C	ASP	192	−31.258	2.78	9.75
ATOM	1403	O	ASP	192	−31.187	2.836	8.531
ATOM	1404	CB	ASP	192	−32.378	4.434	11.258
ATOM	1405	CG	ASP	192	−32.205	5.625	10.356
ATOM	1406	OD1	ASP	192	−31.258	6.43	10.58
ATOM	1407	OD2	ASP	192	−33.032	5.777	9.422
ATOM	1408	HA	ASP	192	−33.355	3.209	9.728
ATOM	1409	H	ASP	192	−33.084	2.197	12.341
ATOM	1410	HB1	ASP	192	−33.266	4.638	11.872
ATOM	1411	HB2	ASP	192	−31.518	4.371	11.939
ATOM	1412	N	ALA	193	−30.21	2.424	10.523
ATOM	1413	CA	ALA	193	−28.914	2.132	9.925
ATOM	1414	C	ALA	193	−28.981	0.833	9.151
ATOM	1415	O	ALA	193	−28.474	0.78	8.042
ATOM	1416	CB	ALA	193	−27.832	2.064	11.033
ATOM	1417	HA	ALA	193	−28.641	2.958	9.249
ATOM	1418	H	ALA	193	−30.316	2.33	11.514
ATOM	1419	HB1	ALA	193	−26.85	1.806	10.608
ATOM	1420	HB2	ALA	193	−27.752	3.041	11.536
ATOM	1421	HB3	ALA	193	−28.113	1.311	11.783
ATOM	1422	N	ASN	194	−29.595	−0.241	9.698
ATOM	1423	CA	ASN	194	−29.638	−1.498	8.953
ATOM	1424	C	ASN	194	−30.258	−1.266	7.599
ATOM	1425	O	ASN	194	−29.748	−1.795	6.625
ATOM	1426	CB	ASN	194	−30.407	−2.635	9.677
ATOM	1427	CG	ASN	194	−30.315	−3.918	8.888
ATOM	1428	OD1	ASN	194	−29.432	−4.713	9.168
ATOM	1429	ND2	ASN	194	−31.193	−4.151	7.89
ATOM	1430	HA	ASN	194	−28.603	−1.838	8.799
ATOM	1431	H	ASN	194	−30.02	−0.194	10.604
ATOM	1432	HB1	ASN	194	−29.974	−2.815	10.672
ATOM	1433	HB2	ASN	194	−31.46	−2.349	9.804
ATOM	1434	HD22	ASN	194	−31.101	−4.984	7.344
ATOM	1435	HD21	ASN	194	−31.917	−3.501	7.665
ATOM	1436	N	SER	195	−31.356	−0.485	7.501
ATOM	1437	CA	SER	195	−31.933	−0.246	6.182
ATOM	1438	C	SER	195	−30.988	0.599	5.362
ATOM	1439	O	SER	195	−30.706	0.247	4.227
ATOM	1440	CB	SER	195	−33.357	0.365	6.242
ATOM	1441	OG	SER	195	−33.914	0.359	4.914
ATOM	1442	HA	SER	195	−32.014	−1.217	5.676
ATOM	1443	H	SER	195	−31.763	−0.041	8.304
ATOM	1444	HB1	SER	195	−33.974	−0.257	6.914
ATOM	1445	HB2	SER	195	−33.32	1.39	6.647
ATOM	1446	HG	SER	195	−34.84	0.592	4.882
ATOM	1447	N	GLN	196	−30.471	1.713	5.929
ATOM	1448	CA	GLN	196	−29.528	2.542	5.179
ATOM	1449	C	GLN	196	−28.441	1.695	4.553
ATOM	1450	O	GLN	196	−28.178	1.827	3.366
ATOM	1451	CB	GLN	196	−28.847	3.576	6.119
ATOM	1452	CG	GLN	196	−27.851	4.512	5.389
ATOM	1453	CD	GLN	196	−27.254	5.527	6.338
ATOM	1454	OE1	GLN	196	−27.325	5.353	7.544
ATOM	1455	NE2	GLN	196	−26.641	6.611	5.824
ATOM	1456	HA	GLN	196	−30.085	3.076	4.391
ATOM	1457	H	GLN	196	−30.731	1.985	6.861
ATOM	1458	HB1	GLN	196	−29.622	4.186	6.607
ATOM	1459	HB2	GLN	196	−28.291	3.042	6.902
ATOM	1460	HG1	GLN	196	−27.02	3.929	4.961
ATOM	1461	HG2	GLN	196	−28.375	5.023	4.569
ATOM	1462	HE22	GLN	196	−26.227	7.284	6.437
ATOM	1463	HE21	GLN	196	−26.599	6.751	4.839
ATOM	1464	N	PHE	197	−27.776	0.827	5.348
ATOM	1465	CA	PHE	197	−26.635	0.083	4.821
ATOM	1466	C	PHE	197	−27.051	−1.164	4.073
ATOM	1467	O	PHE	197	−26.392	−1.492	3.099
ATOM	1468	CB	PHE	197	−25.592	−0.207	5.932
ATOM	1469	CG	PHE	197	−24.934	1.118	6.36
ATOM	1470	CD1	PHE	197	−24.002	1.734	5.517
ATOM	1471	CD2	PHE	197	−25.246	1.73	7.579
ATOM	1472	CE1	PHE	197	−23.338	2.898	5.914
ATOM	1473	CE2	PHE	197	−24.602	2.906	7.973
ATOM	1474	CZ	PHE	197	−23.641	3.489	7.144
ATOM	1475	HA	PHE	197	−26.115	0.717	4.091
ATOM	1476	H	PHE	197	−28.048	0.684	6.303
ATOM	1477	HB1	PHE	197	−26.067	−0.727	6.779
ATOM	1478	HB2	PHE	197	−24.803	−0.865	5.536
ATOM	1479	HD2	PHE	197	−25.993	1.296	8.229
ATOM	1480	HE2	PHE	197	−24.849	3.368	8.924
ATOM	1481	HZ	PHE	197	−23.133	4.397	7.454
ATOM	1482	HE1	PHE	197	−22.588	3.342	5.267
ATOM	1483	HD1	PHE	197	−23.786	1.309	4.542
ATOM	1484	N	THR	198	−28.129	−1.88	4.464
ATOM	1485	CA	THR	198	−28.527	−3.054	3.684
ATOM	1486	C	THR	198	−28.9	−2.565	2.304
ATOM	1487	O	THR	198	−28.469	−3.152	1.323
ATOM	1488	CB	THR	198	−29.69	−3.9	4.288
ATOM	1489	OG1	THR	198	−29.436	−4.309	5.64
ATOM	1490	CG2	THR	198	−29.866	−5.229	3.508
ATOM	1491	HA	THR	198	−27.65	−3.712	3.584
ATOM	1492	H	THR	198	−28.688	−1.584	5.239
ATOM	1493	HB	THR	198	−30.628	−3.318	4.256
ATOM	1494	HG1	THR	198	−29.298	−3.581	6.238
ATOM	1495	HG23	THR	198	−30.112	−5.032	2.458
ATOM	1496	HG21	THR	198	−28.939	−5.824	3.545
ATOM	1497	HG22	THR	198	−30.671	−5.832	3.953
ATOM	1498	N	SER	199	−29.688	−1.471	2.206
ATOM	1499	CA	SER	199	−29.974	−0.909	0.89
ATOM	1500	C	SER	199	−28.687	−0.519	0.199
ATOM	1501	O	SER	199	−28.528	−0.835	−0.97
ATOM	1502	CB	SER	199	−30.926	0.307	0.981
ATOM	1503	OG	SER	199	−32.165	−0.171	1.532
ATOM	1504	HA	SER	199	−30.496	−1.669	0.293
ATOM	1505	H	SER	199	−30.06	−1.009	3.018
ATOM	1506	HB1	SER	199	−30.483	1.084	1.625
ATOM	1507	HB2	SER	199	−31.092	0.728	−0.026
ATOM	1508	HG	SER	199	−32.816	0.516	1.627
ATOM	1509	N	THR	200	−27.749	0.163	0.897
ATOM	1510	CA	THR	200	−26.505	0.564	0.236
ATOM	1511	C	THR	200	−25.854	−0.657	−0.374
ATOM	1512	O	THR	200	−25.469	−0.616	−1.532
ATOM	1513	CB	THR	200	−25.461	1.255	1.165
ATOM	1514	OG1	THR	200	−25.972	2.467	1.75
ATOM	1515	CG2	THR	200	−24.182	1.663	0.388
ATOM	1516	HA	THR	200	−26.766	1.279	−0.559
ATOM	1517	H	THR	200	−27.9	0.395	1.86
ATOM	1518	HB	THR	200	−25.15	0.552	1.954
ATOM	1519	HG1	THR	200	−26.725	2.332	2.317
ATOM	1520	HG23	THR	200	−23.66	0.78	−0.008
ATOM	1521	HG21	THR	200	−24.438	2.333	−0.448
ATOM	1522	HG22	THR	200	−23.493	2.196	1.062
ATOM	1523	N	TYR	201	−25.704	−1.762	0.389
ATOM	1524	CA	TYR	201	−25.041	−2.932	−0.178
ATOM	1525	C	TYR	201	−25.896	−3.567	−1.261
ATOM	1526	O	TYR	201	−25.343	−3.964	−2.275
ATOM	1527	CB	TYR	201	−24.672	−3.978	0.907
ATOM	1528	CG	TYR	201	−23.68	−3.47	1.968
ATOM	1529	CD1	TYR	201	−24.039	−3.407	3.32
ATOM	1530	CD2	TYR	201	−22.384	−3.094	1.593
ATOM	1531	CE1	TYR	201	−23.095	−3.046	4.287
ATOM	1532	CE2	TYR	201	−21.439	−2.736	2.559
ATOM	1533	CZ	TYR	201	−21.776	−2.768	3.914
ATOM	1534	OH	TYR	201	−20.793	−2.532	4.877
ATOM	1535	HA	TYR	201	−24.106	−2.595	−0.657
ATOM	1536	H	TYR	201	−26.045	−1.799	1.333
ATOM	1537	HB2	TYR	201	−25.591	−4.363	1.375
ATOM	1538	HB1	TYR	201	−24.156	−4.81	0.411
ATOM	1539	HD2	TYR	201	−22.094	−3.089	0.548
ATOM	1540	HE2	TYR	201	−20.438	−2.443	2.26
ATOM	1541	HE1	TYR	201	−23.382	−2.989	5.329
ATOM	1542	HD1	TYR	201	−25.048	−3.648	3.634
ATOM	1543	HH	TYR	201	−20.912	−3.068	5.653
ATOM	1544	N	ILE	202	−27.235	−3.683	−1.098
ATOM	1545	CA	ILE	202	−28.067	−4.24	−2.176
ATOM	1546	C	ILE	202	−27.738	−3.558	−3.483
ATOM	1547	O	ILE	202	−27.602	−4.232	−4.492
ATOM	1548	CB	ILE	202	−29.596	−4.12	−1.871
ATOM	1549	CG1	ILE	202	−30.032	−5.248	−0.885
ATOM	1550	CG2	ILE	202	−30.464	−4.14	−3.166
ATOM	1551	CD1	ILE	202	−31.335	−4.96	−0.102
ATOM	1552	HA	ILE	202	−27.815	−5.303	−2.314
ATOM	1553	H	ILE	202	−27.668	−3.375	−0.247
ATOM	1554	HB	ILE	202	−29.763	−3.139	−1.406
ATOM	1555	HG11	ILE	202	−30.204	−6.172	−1.458
ATOM	1556	HG12	ILE	202	−29.238	−5.427	−0.142
ATOM	1557	HD11	ILE	202	−32.183	−4.872	−0.787
ATOM	1558	HD12	ILE	202	−31.56	−5.781	0.595
ATOM	1559	HD13	ILE	202	−31.228	−4.032	0.476
ATOM	1560	HG21	ILE	202	−30.265	−5.058	−3.739
ATOM	1561	HG22	ILE	202	−31.535	−4.095	−2.927
ATOM	1562	HG23	ILE	202	−30.248	−3.272	−3.809
ATOM	1563	N	LEU	203	−27.609	−2.215	−3.492
ATOM	1564	CA	LEU	203	−27.299	−1.538	−4.75
ATOM	1565	C	LEU	203	−26.03	−2.091	−5.359
ATOM	1566	O	LEU	203	−25.955	−2.182	−6.574
ATOM	1567	CB	LEU	203	−27.079	−0.017	−4.562
ATOM	1568	CG	LEU	203	−28.33	0.779	−4.098
ATOM	1569	CD1	LEU	203	−27.875	2.216	−3.727
ATOM	1570	CD2	LEU	203	−29.448	0.801	−5.177
ATOM	1571	HA	LEU	203	−28.121	−1.716	−5.459
ATOM	1572	H	LEU	203	−27.711	−1.688	−2.644
ATOM	1573	HB1	LEU	203	−26.298	0.095	−3.8
ATOM	1574	HB2	LEU	203	−26.709	0.42	−5.504
ATOM	1575	HG	LEU	203	−28.765	0.336	−3.189
ATOM	1576	HD21	LEU	203	−29.902	−0.191	−5.313
ATOM	1577	HD22	LEU	203	−30.246	1.488	−4.868
ATOM	1578	HD23	LEU	203	−29.059	1.144	−6.143
ATOM	1579	HD11	LEU	203	−27.379	2.703	−4.579
ATOM	1580	HD12	LEU	203	−28.748	2.805	−3.425
ATOM	1581	HD13	LEU	203	−27.168	2.203	−2.884
ATOM	1582	N	THR	204	−25.015	−2.47	−4.551
ATOM	1583	CA	THR	204	−23.815	−3.064	−5.137
ATOM	1584	C	THR	204	−24.215	−4.342	−5.832
ATOM	1585	O	THR	204	−23.84	−4.544	−6.976
ATOM	1586	CB	THR	204	−22.689	−3.344	−4.099
ATOM	1587	OG1	THR	204	−22.224	−2.119	−3.506
ATOM	1588	CG2	THR	204	−21.462	−4.007	−4.773
ATOM	1589	HA	THR	204	−23.405	−2.379	−5.894
ATOM	1590	H	THR	204	−25.096	−2.403	−3.556
ATOM	1591	HB	THR	204	−23.052	−4.025	−3.311
ATOM	1592	HG1	THR	204	−22.905	−1.663	−3.026
ATOM	1593	HG23	THR	204	−21.717	−5	−5.169
ATOM	1594	HG21	THR	204	−21.11	−3.373	−5.598
ATOM	1595	HG22	THR	204	−20.645	−4.121	−4.043
ATOM	1596	N	ALA	205	−24.983	−5.226	−5.16
ATOM	1597	CA	ALA	205	−25.378	−6.463	−5.825
ATOM	1598	C	ALA	205	−26.227	−6.162	−7.039
ATOM	1599	O	ALA	205	−26.106	−6.887	−8.013
ATOM	1600	CB	ALA	205	−26.119	−7.426	−4.872
ATOM	1601	HA	ALA	205	−24.459	−6.977	−6.155
ATOM	1602	H	ALA	205	−25.309	−5.038	−4.229
ATOM	1603	HB1	ALA	205	−26.325	−8.381	−5.375
ATOM	1604	HB2	ALA	205	−25.478	−7.635	−4.004
ATOM	1605	HB3	ALA	205	−27.064	−6.971	−4.538
ATOM	1606	N	MET	206	−27.078	−5.109	−7.036
ATOM	1607	CA	MET	206	−27.773	−4.756	−8.273
ATOM	1608	C	MET	206	−26.744	−4.386	−9.311
ATOM	1609	O	MET	206	−26.754	−4.95	−10.392
ATOM	1610	CB	MET	206	−28.768	−3.566	−8.174
ATOM	1611	CG	MET	206	−30.008	−3.917	−7.321
ATOM	1612	SD	MET	206	−31.181	−2.518	−7.33
ATOM	1613	CE	MET	206	−32.456	−3.147	−8.472
ATOM	1614	HA	MET	206	−28.327	−5.635	−8.632
ATOM	1615	H	MET	206	−27.199	−4.535	−6.223
ATOM	1616	HB1	MET	206	−28.273	−2.675	−7.761
ATOM	1617	HB2	MET	206	−29.121	−3.32	−9.189
ATOM	1618	HG1	MET	206	−30.493	−4.796	−7.763
ATOM	1619	HG2	MET	206	−29.722	−4.143	−6.283
ATOM	1620	LPD1	MET	206	−31.436	−2.402	−6.711
ATOM	1621	LPD2	MET	206	−30.892	−1.951	−7.566
ATOM	1622	HE1	MET	206	−32.972	−4.004	−8.014
ATOM	1623	HE2	MET	206	−33.19	−2.355	−8.678
ATOM	1624	HE3	MET	206	−31.995	−3.465	−9.418
ATOM	1625	N	ALA	207	−25.842	−3.43	−9.014
ATOM	1626	CA	ALA	207	−24.89	−3.005	−10.034
ATOM	1627	C	ALA	207	−24.123	−4.198	−10.561
ATOM	1628	O	ALA	207	−23.868	−4.262	−11.754
ATOM	1629	CB	ALA	207	−23.923	−1.936	−9.471
ATOM	1630	HA	ALA	207	−25.462	−2.555	−10.865
ATOM	1631	H	ALA	207	−25.818	−3.005	−8.106
ATOM	1632	HB1	ALA	207	−23.324	−1.532	−10.296
ATOM	1633	HB2	ALA	207	−24.487	−1.107	−9.017
ATOM	1634	HB3	ALA	207	−23.257	−2.374	−8.712
ATOM	1635	N	ILE	208	−23.762	−5.168	−9.69
ATOM	1636	CA	ILE	208	−23.122	−6.386	−10.186
ATOM	1637	C	ILE	208	−24.118	−7.128	−11.055
ATOM	1638	O	ILE	208	−23.765	−7.493	−12.164
ATOM	1639	CB	ILE	208	−22.563	−7.283	−9.038
ATOM	1640	CG1	ILE	208	−21.379	−6.556	−8.324
ATOM	1641	CG2	ILE	208	−22.129	−8.672	−9.589
ATOM	1642	CD1	ILE	208	−20.905	−7.252	−7.02
ATOM	1643	HA	ILE	208	−22.263	−6.098	−10.812
ATOM	1644	H	ILE	208	−23.984	−5.091	−8.715
ATOM	1645	HB	ILE	208	−23.375	−7.455	−8.315
ATOM	1646	HG11	ILE	208	−20.524	−6.474	−9.015
ATOM	1647	HG12	ILE	208	−21.682	−5.533	−8.055
ATOM	1648	HD11	ILE	208	−20.432	−8.223	−7.223
ATOM	1649	HD12	ILE	208	−20.158	−6.621	−6.512
ATOM	1650	HD13	ILE	208	−21.755	−7.406	−6.336
ATOM	1651	HG21	ILE	208	−21.338	−8.556	−10.346
ATOM	1652	HG22	ILE	208	−21.758	−9.329	−8.79
ATOM	1653	HG23	ILE	208	−22.983	−9.188	−10.05
ATOM	1654	N	ASP	209	−25.363	−7.368	−10.587
ATOM	1655	CA	ASP	209	−26.348	−8.071	−11.417
ATOM	1656	C	ASP	209	−26.444	−7.43	−12.783
ATOM	1657	O	ASP	209	−26.468	−8.128	−13.786
ATOM	1658	CB	ASP	209	−27.757	−8.053	−10.763
ATOM	1659	CG	ASP	209	−28.81	−8.727	−11.605
ATOM	1660	OD1	ASP	209	−29.707	−8.017	−12.136
ATOM	1661	OD2	ASP	209	−28.759	−9.977	−11.734
ATOM	1662	HA	ASP	209	−26.026	−9.117	−11.528
ATOM	1663	H	ASP	209	−25.629	−7.063	−9.672
ATOM	1664	HB1	ASP	209	−27.713	−8.547	−9.782
ATOM	1665	HB2	ASP	209	−28.077	−7.016	−10.602
ATOM	1666	N	ARG	210	−26.503	−6.083	−12.844
ATOM	1667	CA	ARG	210	−26.683	−5.428	−14.135
ATOM	1668	C	ARG	210	−25.407	−5.554	−14.933
ATOM	1669	O	ARG	210	−25.481	−5.843	−16.116
ATOM	1670	CB	ARG	210	−27.106	−3.939	−14
ATOM	1671	CG	ARG	210	−28.309	−3.683	−13.042
ATOM	1672	CD	ARG	210	−29.417	−4.772	−13.104
ATOM	1673	NE	ARG	210	−29.992	−4.924	−14.444
ATOM	1674	CZ	ARG	210	−30.731	−5.949	−14.812
ATOM	1675	NH1	ARG	210	−31.034	−6.954	−14.024
ATOM	1676	NH2	ARG	210	−31.2	−5.97	−16.036
ATOM	1677	HA	ARG	210	−27.476	−5.954	−14.693
ATOM	1678	H	ARG	210	−26.414	−5.526	−12.016
ATOM	1679	HB1	ARG	210	−26.252	−3.364	−13.617
ATOM	1680	HB2	ARG	210	−27.335	−3.567	−15.013
ATOM	1681	HG1	ARG	210	−27.958	−3.615	−12.002
ATOM	1682	HG2	ARG	210	−28.733	−2.697	−13.274
ATOM	1683	HD1	ARG	210	−28.947	−5.695	−12.742
ATOM	1684	HD2	ARG	210	−30.224	−4.505	−12.401
ATOM	1685	HE	ARG	210	−29.791	−4.179	−15.131
ATOM	1686	HH12	ARG	210	−31.617	−7.738	−14.352
ATOM	1687	HH11	ARG	210	−30.694	−7.012	−13.053
ATOM	1688	HH22	ARG	210	−31.783	−6.753	−16.36
ATOM	1689	HH21	ARG	210	−31.017	−5.198	−16.699
ATOM	1690	N	TYR	211	−24.222	−5.36	−14.313
ATOM	1691	CA	TYR	211	−22.979	−5.6	−15.045
ATOM	1692	C	TYR	211	−23.001	−7	−15.617
ATOM	1693	O	TYR	211	−22.715	−7.162	−16.794
ATOM	1694	CB	TYR	211	−21.731	−5.451	−14.134
ATOM	1695	CG	TYR	211	−20.494	−6.023	−14.841
ATOM	1696	CD1	TYR	211	−19.759	−5.228	−15.724
ATOM	1697	CD2	TYR	211	−20.097	−7.347	−14.616
ATOM	1698	CE1	TYR	211	−18.658	−5.76	−16.401
ATOM	1699	CE2	TYR	211	−18.996	−7.879	−15.293
ATOM	1700	CZ	TYR	211	−18.28	−7.092	−16.198
ATOM	1701	OH	TYR	211	−17.197	−7.645	−16.884
ATOM	1702	HA	TYR	211	−22.898	−4.882	−15.877
ATOM	1703	H	TYR	211	−24.179	−5.103	−13.344
ATOM	1704	HB2	TYR	211	−21.58	−4.392	−13.869
ATOM	1705	HB1	TYR	211	−21.884	−6.007	−13.199
ATOM	1706	HD2	TYR	211	−20.643	−7.972	−13.918
ATOM	1707	HE2	TYR	211	−18.695	−8.907	−15.119
ATOM	1708	HE1	TYR	211	−18.102	−5.139	−17.093
ATOM	1709	HD1	TYR	211	−20.05	−4.197	−15.89
ATOM	1710	HH	TYR	211	−17.085	−7.276	−17.754
ATOM	1711	N	LEU	212	−23.338	−8.015	−14.79
ATOM	1712	CA	LEU	212	−23.344	−9.392	−15.276
ATOM	1713	C	LEU	212	−24.317	−9.526	−16.425
ATOM	1714	O	LEU	212	−23.98	−10.127	−17.433
ATOM	1715	CB	LEU	212	−23.719	−10.425	−14.178
ATOM	1716	CG	LEU	212	−22.646	−10.604	−13.059
ATOM	1717	CD1	LEU	212	−23.244	−11.455	−11.904
ATOM	1718	CD2	LEU	212	−21.347	−11.291	−13.574
ATOM	1719	HA	LEU	212	−22.34	−9.628	−15.639
ATOM	1720	H	LEU	212	−23.601	−7.836	−13.841
ATOM	1721	HB1	LEU	212	−24.668	−10.093	−13.731
ATOM	1722	HB2	LEU	212	−23.897	−11.407	−14.646
ATOM	1723	HG	LEU	212	−22.371	−9.619	−12.649
ATOM	1724	HD21	LEU	212	−20.803	−10.675	−14.303
ATOM	1725	HD22	LEU	212	−20.66	−11.481	−12.735
ATOM	1726	HD23	LEU	212	−21.596	−12.254	−14.044
ATOM	1727	HD11	LEU	212	−23.536	−12.449	−12.274
ATOM	1728	HD12	LEU	212	−22.512	−11.586	−11.091
ATOM	1729	HD13	LEU	212	−24.133	−10.961	−11.484
ATOM	1730	N	ALA	213	−25.545	−8.981	−16.299
ATOM	1731	CA	ALA	213	−26.503	−9.111	−17.395
ATOM	1732	C	ALA	213	−26.132	−8.263	−18.598
ATOM	1733	O	ALA	213	−26.551	−8.607	−19.692
ATOM	1734	CB	ALA	213	−27.924	−8.715	−16.914
ATOM	1735	HA	ALA	213	−26.542	−10.17	−17.709
ATOM	1736	H	ALA	213	−25.807	−8.479	−15.469
ATOM	1737	HB1	ALA	213	−28.656	−8.931	−17.706
ATOM	1738	HB2	ALA	213	−28.2	−9.293	−16.017
ATOM	1739	HB3	ALA	213	−27.962	−7.642	−16.672
ATOM	1740	N	THR	214	−25.38	−7.148	−18.434
ATOM	1741	CA	THR	214	−25.14	−6.226	−19.549
ATOM	1742	C	THR	214	−23.813	−6.401	−20.258
ATOM	1743	O	THR	214	−23.813	−6.527	−21.474
ATOM	1744	CB	THR	214	−25.217	−4.757	−19.036
ATOM	1745	OG1	THR	214	−26.563	−4.506	−18.587
ATOM	1746	CG2	THR	214	−24.821	−3.728	−20.132
ATOM	1747	HA	THR	214	−25.945	−6.317	−20.298
ATOM	1748	H	THR	214	−25.017	−6.908	−17.531
ATOM	1749	HB	THR	214	−24.52	−4.632	−18.188
ATOM	1750	HG1	THR	214	−26.656	−3.649	−18.184
ATOM	1751	HG23	THR	214	−23.755	−3.812	−20.387
ATOM	1752	HG21	THR	214	−25.407	−3.894	−21.047
ATOM	1753	HG22	THR	214	−24.999	−2.703	−19.778
ATOM	1754	N	VAL	215	−22.662	−6.346	−19.55
ATOM	1755	CA	VAL	215	−21.389	−6.1	−20.24
ATOM	1756	C	VAL	215	−20.769	−7.401	−20.698
ATOM	1757	O	VAL	215	−19.726	−7.775	−20.192
ATOM	1758	CB	VAL	215	−20.439	−5.23	−19.36
ATOM	1759	CG1	VAL	215	−19.123	−4.843	−20.099
ATOM	1760	CG2	VAL	215	−21.133	−3.916	−18.902
ATOM	1761	HA	VAL	215	−21.559	−5.502	−21.148
ATOM	1762	H	VAL	215	−22.668	−6.427	−18.55
ATOM	1763	HB	VAL	215	−20.197	−5.829	−18.47
ATOM	1764	HG11	VAL	215	−19.353	−4.301	−21.03
ATOM	1765	HG12	VAL	215	−18.506	−4.19	−19.465
ATOM	1766	HG13	VAL	215	−18.512	−5.72	−20.348
ATOM	1767	HG21	VAL	215	−22.048	−4.114	−18.327
ATOM	1768	HG22	VAL	215	−20.46	−3.33	−18.258
ATOM	1769	HG23	VAL	215	−21.388	−3.3	−19.778
ATOM	1770	N	HIS	216	−21.407	−8.094	−21.672
ATOM	1771	CA	HIS	216	−20.821	−9.293	−22.285
ATOM	1772	C	HIS	216	−19.813	−10.037	−21.432
ATOM	1773	O	HIS	216	−18.687	−10.186	−21.882
ATOM	1774	CB	HIS	216	−20.193	−8.796	−23.616
ATOM	1775	CG	HIS	216	−19.238	−7.658	−23.354
ATOM	1776	ND1	HIS	216	−18.065	−7.81	−22.783
ATOM	1777	CD2	HIS	216	−19.44	−6.358	−23.65
ATOM	1778	CE1	HIS	216	−17.471	−6.663	−22.691
ATOM	1779	NE2	HIS	216	−18.214	−5.775	−23.175
ATOM	1780	HA	HIS	216	−21.612	−10.025	−22.519
ATOM	1781	H	HIS	216	−22.28	−7.76	−22.035
ATOM	1782	HB1	HIS	216	−19.674	−9.61	−24.147
ATOM	1783	HB2	HIS	216	−20.998	−8.433	−24.269
ATOM	1784	HD2	HIS	216	−20.292	−5.87	−24.117
ATOM	1785	HE1	HIS	216	−16.486	−6.48	−22.261
ATOM	1786	HD1	HIS	216	−17.68	−8.71	−22.453
ATOM	1787	N	PRO	217	−20.133	−10.505	−20.2
ATOM	1788	CA	PRO	217	−19.102	−11.056	−19.333
ATOM	1789	C	PRO	217	−19.245	−12.55	−19.148
ATOM	1790	O	PRO	217	−20.095	−13.163	−19.774
ATOM	1791	CB	PRO	217	−19.546	−10.291	−18.066
ATOM	1792	CG	PRO	217	−21.095	−10.282	−18.14
ATOM	1793	CD	PRO	217	−21.473	−10.421	−19.637
ATOM	1794	HA	PRO	217	−18.067	−10.8	−19.614
ATOM	1795	HD2	PRO	217	−22.098	−9.577	−19.956
ATOM	1796	HD1	PRO	217	−22.019	−11.356	−19.841
ATOM	1797	HG2	PRO	217	−21.473	−9.329	−17.737
ATOM	1798	HG1	PRO	217	−21.513	−11.123	−17.562
ATOM	1799	HB1	PRO	217	−19.166	−10.718	−17.125
ATOM	1800	HB2	PRO	217	−19.175	−9.255	−18.144
ATOM	1801	N	ILE	218	−18.405	−13.15	−18.275
ATOM	1802	CA	ILE	218	−18.507	−14.582	−17.995
ATOM	1803	C	ILE	218	−18.226	−15.406	−19.239
ATOM	1804	O	ILE	218	−17.109	−15.886	−19.343
ATOM	1805	CB	ILE	218	−19.824	−14.948	−17.242
ATOM	1806	CG1	ILE	218	−20.069	−14.042	−15.994
ATOM	1807	CG2	ILE	218	−19.859	−16.462	−16.886
ATOM	1808	CD1	ILE	218	−18.959	−14.082	−14.908
ATOM	1809	HA	ILE	218	−17.696	−14.856	−17.298
ATOM	1810	H	ILE	218	−17.7	−12.619	−17.798
ATOM	1811	HB	ILE	218	−20.685	−14.764	−17.905
ATOM	1812	HG11	ILE	218	−20.184	−12.997	−16.324
ATOM	1813	HG12	ILE	218	−21.02	−14.345	−15.525
ATOM	1814	HD11	ILE	218	−18.011	−13.673	−15.285
ATOM	1815	HD12	ILE	218	−19.263	−13.467	−14.046
ATOM	1816	HD13	ILE	218	−18.79	−15.106	−14.546
ATOM	1817	HG21	ILE	218	−18.994	−16.754	−16.274
ATOM	1818	HG22	ILE	218	−20.779	−16.704	−16.331
ATOM	1819	HG23	ILE	218	−19.845	−17.069	−17.802
ATOM	1820	N	SER	219	−19.184	−15.588	−20.179
ATOM	1821	CA	SER	219	−18.971	−16.444	−21.353
ATOM	1822	C	SER	219	−20.308	−16.929	−21.875
ATOM	1823	O	SER	219	−20.628	−16.703	−23.031
ATOM	1824	CB	SER	219	−18.181	−17.762	−21.1
ATOM	1825	OG	SER	219	−18.749	−18.424	−19.953
ATOM	1826	HA	SER	219	−18.463	−15.857	−22.136
ATOM	1827	H	SER	219	−20.049	−15.084	−20.119
ATOM	1828	HB1	SER	219	−18.263	−18.418	−21.985
ATOM	1829	HB2	SER	219	−17.107	−17.568	−20.953
ATOM	1830	HG	SER	219	−18.312	−19.244	−19.744
ATOM	1831	N	SER	220	−21.084	−17.639	−21.026
ATOM	1832	CA	SER	220	−22.261	−18.353	−21.523
ATOM	1833	C	SER	220	−23.242	−18.698	−20.421
ATOM	1834	O	SER	220	−24.404	−18.337	−20.542
ATOM	1835	CB	SER	220	−21.767	−19.676	−22.16
ATOM	1836	OG	SER	220	−21.087	−20.447	−21.152
ATOM	1837	HA	SER	220	−22.785	−17.749	−22.283
ATOM	1838	H	SER	220	−20.784	−17.781	−20.082
ATOM	1839	HB1	SER	220	−22.628	−20.24	−22.559
ATOM	1840	HB2	SER	220	−21.078	−19.447	−22.991
ATOM	1841	HG	SER	220	−20.746	−21.273	−21.484
ATOM	1842	N	THR	221	−22.795	−19.411	−19.359
ATOM	1843	CA	THR	221	−23.698	−19.776	−18.265
ATOM	1844	C	THR	221	−24.408	−18.586	−17.658
ATOM	1845	O	THR	221	−24.04	−17.456	−17.936
ATOM	1846	CB	THR	221	−22.999	−20.571	−17.126
ATOM	1847	OG1	THR	221	−24.02	−21.053	−16.232
ATOM	1848	CG2	THR	221	−21.978	−19.695	−16.35
ATOM	1849	HA	THR	221	−24.471	−20.433	−18.697
ATOM	1850	H	THR	221	−21.853	−19.753	−19.343
ATOM	1851	HB	THR	221	−22.476	−21.435	−17.576
ATOM	1852	HG1	THR	221	−23.673	−21.573	−15.514
ATOM	1853	HG23	THR	221	−21.218	−19.279	−17.028
ATOM	1854	HG21	THR	221	−22.489	−18.865	−15.84
ATOM	1855	HG22	THR	221	−21.464	−20.302	−15.589
ATOM	1856	N	LYS	222	−25.45	−18.836	−16.829
ATOM	1857	CA	LYS	222	−26.31	−17.757	−16.339
ATOM	1858	C	LYS	222	−26.718	−18.03	−14.908
ATOM	1859	O	LYS	222	−26.381	−19.083	−14.392
ATOM	1860	CB	LYS	222	−27.547	−17.66	−17.278
ATOM	1861	CG	LYS	222	−27.099	−17.328	−18.726
ATOM	1862	CD	LYS	222	−28.265	−17.204	−19.738
ATOM	1863	CE	LYS	222	−27.759	−16.688	−21.118
ATOM	1864	NZ	LYS	222	−26.61	−17.458	−21.66
ATOM	1865	HA	LYS	222	−25.773	−16.794	−16.324
ATOM	1866	H	LYS	222	−25.694	−19.776	−16.575
ATOM	1867	HB1	LYS	222	−28.087	−18.62	−17.265
ATOM	1868	HB2	LYS	222	−28.236	−16.877	−16.93
ATOM	1869	HG1	LYS	222	−26.516	−16.392	−18.72
ATOM	1870	HG2	LYS	222	−26.463	−18.151	−19.075
ATOM	1871	HD1	LYS	222	−28.745	−18.19	−19.859
ATOM	1872	HD2	LYS	222	−29.024	−16.507	−19.348
ATOM	1873	HE1	LYS	222	−28.605	−16.726	−21.826
ATOM	1874	HE2	LYS	222	−27.46	−15.63	−21.017
ATOM	1875	HZ1	LYS	222	−26.782	−18.526	−21.643
ATOM	1876	HZ2	LYS	222	−26.397	−17.192	−22.686
ATOM	1877	HZ3	LYS	222	−25.679	−17.28	−21.136
ATOM	1878	N	PHE	223	−27.429	−17.096	−14.237
ATOM	1879	CA	PHE	223	−27.738	−17.306	−12.825
ATOM	1880	C	PHE	223	−28.447	−18.622	−12.586
ATOM	1881	O	PHE	223	−29.419	−18.892	−13.274
ATOM	1882	CB	PHE	223	−28.687	−16.226	−12.238
ATOM	1883	CG	PHE	223	−28.093	−14.818	−12.348
ATOM	1884	CD1	PHE	223	−27.059	−14.434	−11.488
ATOM	1885	CD2	PHE	223	−28.577	−13.905	−13.292
ATOM	1886	CE1	PHE	223	−26.528	−13.143	−11.556
ATOM	1887	CE2	PHE	223	−28.031	−12.622	−13.382
ATOM	1888	CZ	PHE	223	−27.001	−12.245	−12.516
ATOM	1889	HA	PHE	223	−26.784	−17.264	−12.274
ATOM	1890	H	PHE	223	−27.69	−16.231	−14.665
ATOM	1891	HB1	PHE	223	−29.656	−16.267	−12.761
ATOM	1892	HB2	PHE	223	−28.87	−16.429	−11.17
ATOM	1893	HD2	PHE	223	−29.38	−14.189	−13.96
ATOM	1894	HE2	PHE	223	−28.405	−11.919	−14.12
ATOM	1895	HZ	PHE	223	−26.575	−11.253	−12.592
ATOM	1896	HE1	PHE	223	−25.752	−12.842	−10.86
ATOM	1897	HD1	PHE	223	−26.668	−15.138	−10.764
ATOM	1898	N	ARG	224	−28.024	−19.429	−11.586
ATOM	1899	CA	ARG	224	−28.896	−20.503	−11.113
ATOM	1900	C	ARG	224	−30.006	−19.726	−10.434
ATOM	1901	O	ARG	224	−29.897	−19.41	−9.259
ATOM	1902	CB	ARG	224	−28.147	−21.487	−10.176
ATOM	1903	CG	ARG	224	−27.112	−22.329	−10.976
ATOM	1904	CD	ARG	224	−26.359	−23.349	−10.078
ATOM	1905	NE	ARG	224	−25.404	−24.149	−10.855
ATOM	1906	CZ	ARG	224	−24.666	−25.11	−10.343
ATOM	1907	NH1	ARG	224	−24.71	−25.438	−9.074
ATOM	1908	NH2	ARG	224	−23.849	−25.772	−11.13
ATOM	1909	HA	ARG	224	−29.288	−21.091	−11.96
ATOM	1910	H	ARG	224	−27.201	−19.214	−11.058
ATOM	1911	HB1	ARG	224	−27.63	−20.915	−9.393
ATOM	1912	HB2	ARG	224	−28.882	−22.155	−9.699
ATOM	1913	HG1	ARG	224	−27.632	−22.887	−11.773
ATOM	1914	HG2	ARG	224	−26.38	−21.655	−11.451
ATOM	1915	HD1	ARG	224	−25.828	−22.787	−9.291
ATOM	1916	HD2	ARG	224	−27.114	−24.009	−9.617
ATOM	1917	HE	ARG	224	−25.321	−23.937	−11.863
ATOM	1918	HH12	ARG	224	−24.121	−26.197	−8.701
ATOM	1919	HH11	ARG	224	−25.327	−24.953	−8.411
ATOM	1920	HH22	ARG	224	−23.255	−26.531	−10.766
ATOM	1921	HH21	ARG	224	−23.778	−25.552	−12.135
ATOM	1922	N	LYS	225	−31.051	−19.359	−11.213
ATOM	1923	CA	LYS	225	−31.883	−18.209	−10.866
ATOM	1924	C	LYS	225	−32.312	−18.032	−9.415
ATOM	1925	O	LYS	225	−32.187	−16.901	−8.968
ATOM	1926	CB	LYS	225	−32.967	−17.93	−11.957
ATOM	1927	CG	LYS	225	−34.11	−18.977	−12.035
ATOM	1928	CD	LYS	225	−34.922	−18.875	−13.359
ATOM	1929	CE	LYS	225	−36.27	−19.653	−13.301
ATOM	1930	NZ	LYS	225	−36.106	−21.103	−13.033
ATOM	1931	HA	LYS	225	−31.179	−17.372	−11.013
ATOM	1932	HB1	LYS	225	−33.404	−16.938	−11.785
ATOM	1933	HB2	LYS	225	−32.47	−17.893	−12.942
ATOM	1934	HG1	LYS	225	−33.673	−19.986	−11.988
ATOM	1935	HG2	LYS	225	−34.782	−18.819	−11.176
ATOM	1936	HD1	LYS	225	−35.138	−17.819	−13.587
ATOM	1937	HD2	LYS	225	−34.31	−19.264	−14.191
ATOM	1938	HE1	LYS	225	−36.915	−19.211	−12.522
ATOM	1939	HE2	LYS	225	−36.785	−19.516	−14.268
ATOM	1940	HZ1	LYS	225	−35.738	−21.308	−12.037
ATOM	1941	HZ2	LYS	225	−37.049	−21.629	−13.106
ATOM	1942	HZ3	LYS	225	−35.432	−21.571	−13.737
ATOM	1943	H	LYS	225	−31.125	−19.711	−12.148
ATOM	1944	N	PRO	226	−32.802	−19	−8.594
ATOM	1945	CA	PRO	226	−33.15	−18.655	−7.217
ATOM	1946	C	PRO	226	−31.987	−18.735	−6.248
ATOM	1947	O	PRO	226	−32.089	−18.139	−5.186
ATOM	1948	CB	PRO	226	−34.121	−19.824	−6.922
ATOM	1949	CG	PRO	226	−33.493	−21.016	−7.681
ATOM	1950	CD	PRO	226	−33.044	−20.375	−9.017
ATOM	1951	HA	PRO	226	−33.668	−17.685	−7.123
ATOM	1952	HD2	PRO	226	−33.896	−20.425	−9.704
ATOM	1953	HD1	PRO	226	−32.175	−20.892	−9.449
ATOM	1954	HG2	PRO	226	−34.2	−21.851	−7.817
ATOM	1955	HG1	PRO	226	−32.624	−21.392	−7.118
ATOM	1956	HB1	PRO	226	−34.255	−20.018	−5.845
ATOM	1957	HB2	PRO	226	−35.106	−19.599	−7.366
ATOM	1958	N	SER	227	−30.889	−19.473	−6.537
ATOM	1959	CA	SER	227	−29.894	−19.714	−5.493
ATOM	1960	C	SER	227	−28.952	−18.544	−5.394
ATOM	1961	O	SER	227	−28.763	−18.048	−4.295
ATOM	1962	CB	SER	227	−29.072	−21.005	−5.727
ATOM	1963	CG	SER	227	−28.275	−20.873	−6.915
ATOM	1964	HA	SER	227	−30.408	−19.846	−4.524
ATOM	1965	H	SER	227	−30.729	−19.867	−7.445
ATOM	1966	HB1	SER	227	−28.415	−21.174	−4.856
ATOM	1967	HB2	SER	227	−29.763	−21.86	−5.823
ATOM	1968	HG	SER	227	−27.727	−21.638	−7.062
ATOM	1969	N	VAL	228	−28.352	−18.076	−6.512
ATOM	1970	CA	VAL	228	−27.463	−16.919	−6.408
ATOM	1971	C	VAL	228	−28.234	−15.823	−5.71
ATOM	1972	O	VAL	228	−27.73	−15.273	−4.743
ATOM	1973	CB	VAL	228	−26.907	−16.411	−7.773
ATOM	1974	CG1	VAL	228	−26.159	−15.057	−7.587
ATOM	1975	CG2	VAL	228	−25.947	−17.458	−8.406
ATOM	1976	HA	VAL	228	−26.608	−17.199	−5.771
ATOM	1977	H	VAL	228	−28.531	−18.501	−7.402
ATOM	1978	HB	VAL	228	−27.751	−16.247	−8.464
ATOM	1979	HG11	VAL	228	−25.374	−15.158	−6.821
ATOM	1980	HG12	VAL	228	−25.682	−14.737	−8.525
ATOM	1981	HG13	VAL	228	−26.851	−14.259	−7.276
ATOM	1982	HG21	VAL	228	−26.45	−18.424	−8.56
ATOM	1983	HG22	VAL	228	−25.585	−17.107	−9.385
ATOM	1984	HG23	VAL	228	−25.076	−17.622	−7.753
ATOM	1985	N	ALA	229	−29.465	−15.52	−6.18
ATOM	1986	CA	ALA	229	−30.284	−14.507	−5.515
ATOM	1987	C	ALA	229	−30.296	−14.706	−4.013
ATOM	1988	O	ALA	229	−30.153	−13.75	−3.267
ATOM	1989	CB	ALA	229	−31.749	−14.581	−6.018
ATOM	1990	HA	ALA	229	−29.889	−13.509	−5.76
ATOM	1991	H	ALA	229	−29.834	−15.989	−6.985
ATOM	1992	HB1	ALA	229	−32.324	−13.766	−5.56
ATOM	1993	HB2	ALA	229	−31.8	−14.477	−7.112
ATOM	1994	HB3	ALA	229	−32.21	−15.541	−5.742
ATOM	1995	N	THR	230	−30.471	−15.962	−3.548
ATOM	1996	CA	THR	230	−30.499	−16.209	−2.107
ATOM	1997	C	THR	230	−29.125	−15.967	−1.52
ATOM	1998	O	THR	230	−29.023	−15.334	−0.479
ATOM	1999	CB	THR	230	−30.966	−17.656	−1.773
ATOM	2000	OG1	THR	230	−32.306	−17.894	−2.249
ATOM	2001	CG2	THR	230	−30.976	−17.904	−0.242
ATOM	2002	HA	THR	230	−31.222	−15.516	−1.647
ATOM	2003	H	THR	230	−30.549	−16.736	−4.179
ATOM	2004	HB	THR	230	−30.278	−18.388	−2.23
ATOM	2005	HG1	THR	230	−32.397	−17.847	−3.197
ATOM	2006	HG23	THR	230	−29.963	−17.833	0.182
ATOM	2007	HG21	THR	230	−31.625	−17.17	0.259
ATOM	2008	HG22	THR	230	−31.366	−18.913	−0.034
ATOM	2009	N	LEU	231	−28.046	−16.467	−2.163
ATOM	2010	CA	LEU	231	−26.712	−16.287	−1.595
ATOM	2011	C	LEU	231	−26.438	−14.81	−1.42
ATOM	2012	O	LEU	231	−25.967	−14.411	−0.366
ATOM	2013	CB	LEU	231	−25.569	−16.872	−2.476
ATOM	2014	CG	LEU	231	−25.617	−18.413	−2.716
ATOM	2015	CD1	LEU	231	−24.434	−18.834	−3.634
ATOM	2016	CD2	LEU	231	−25.569	−19.222	−1.389
ATOM	2017	HA	LEU	231	−26.687	−16.745	−0.594
ATOM	2018	H	LEU	231	−28.149	−16.947	−3.036
ATOM	2019	HB1	LEU	231	−25.593	−16.363	−3.453
ATOM	2020	HB2	LEU	231	−24.607	−16.628	−1.997
ATOM	2021	HG	LEU	231	−26.544	−18.686	−3.244
ATOM	2022	HD21	LEU	231	−26.486	−19.074	−0.799
ATOM	2023	HD22	LEU	231	−25.485	−20.299	−1.6
ATOM	2024	HD23	LEU	231	−24.702	−18.917	−0.784
ATOM	2025	HD11	LEU	231	−23.472	−18.62	−3.143
ATOM	2026	HD12	LEU	231	−24.479	−19.911	−3.857
ATOM	2027	HD13	LEU	231	−24.468	−18.287	−4.589
ATOM	2028	N	VAL	232	−26.721	−13.975	−2.445
ATOM	2029	CA	VAL	232	−26.462	−12.547	−2.283
ATOM	2030	C	VAL	232	−27.332	−12.007	−1.165
ATOM	2031	O	VAL	232	−26.804	−11.27	−0.35
ATOM	2032	CB	VAL	232	−26.468	−11.687	−3.587
ATOM	2033	CG1	VAL	232	−25.206	−11.976	−4.451
ATOM	2034	CG2	VAL	232	−27.729	−11.873	−4.471
ATOM	2035	HA	VAL	232	−25.43	−12.466	−1.904
ATOM	2036	H	VAL	232	−27.126	−14.323	−3.292
ATOM	2037	HB	VAL	232	−26.421	−10.628	−3.279
ATOM	2038	HG11	VAL	232	−25.216	−11.364	−5.368
ATOM	2039	HG12	VAL	232	−25.179	−13.039	−4.739
ATOM	2040	HG13	VAL	232	−24.283	−11.74	−3.898
ATOM	2041	HG21	VAL	232	−28.647	−11.772	−3.875
ATOM	2042	HG22	VAL	232	−27.741	−11.125	−5.279
ATOM	2043	HG23	VAL	232	−27.726	−12.85	−4.963
ATOM	2044	N	ILE	233	−28.635	−12.355	−1.037
ATOM	2045	CA	ILE	233	−29.384	−11.892	0.142
ATOM	2046	C	ILE	233	−28.6	−12.232	1.394
ATOM	2047	O	ILE	233	−28.435	−11.372	2.249
ATOM	2048	CB	ILE	233	−30.852	−12.434	0.22
ATOM	2049	CG1	ILE	233	−31.769	−11.616	−0.746
ATOM	2050	CG2	ILE	233	−31.424	−12.395	1.67
ATOM	2051	CD1	ILE	233	−33.274	−11.994	−0.68
ATOM	2052	HA	ILE	233	−29.431	−10.793	0.117
ATOM	2053	H	ILE	233	−29.079	−12.96	−1.703
ATOM	2054	HB	ILE	233	−30.846	−13.493	−0.083
ATOM	2055	HG11	ILE	233	−31.697	−10.542	−0.505
ATOM	2056	HG12	ILE	233	−31.412	−11.75	−1.781
ATOM	2057	HD11	ILE	233	−33.713	−11.828	0.313
ATOM	2058	HD12	ILE	233	−33.843	−11.352	−1.367
ATOM	2059	HD13	ILE	233	−33.415	−13.049	−0.96
ATOM	2060	HG21	ILE	233	−31.615	−11.351	1.952
ATOM	2061	HG22	ILE	233	−32.363	−12.962	1.744
ATOM	2062	HG23	ILE	233	−30.753	−12.853	2.41
ATOM	2063	N	CYS	234	−28.117	−13.485	1.536
ATOM	2064	CA	CYS	234	−27.415	−13.848	2.767
ATOM	2065	C	CYS	234	−26.203	−12.962	2.967
ATOM	2066	O	CYS	234	−26.037	−12.403	4.041
ATOM	2067	CB	CYS	234	−26.98	−15.338	2.769
ATOM	2068	SG	CYS	234	−28.457	−16.395	2.59
ATOM	2069	HA	CYS	234	−28.105	−13.698	3.615
ATOM	2070	H	CYS	234	−28.247	−14.17	0.813
ATOM	2071	HB1	CYS	234	−26.288	−15.543	1.938
ATOM	2072	HB2	CYS	234	−26.474	−15.582	3.717
ATOM	2073	HG	CYS	234	−27.996	−17.292	2.564
ATOM	2074	LPG1	CYS	234	−28.878	−16.339	3.12
ATOM	2075	LPG2	CYS	234	−28.797	−16.266	2.017
ATOM	2076	N	LEU	235	−25.34	−12.816	1.937
ATOM	2077	CA	LEU	235	−24.174	−11.94	2.08
ATOM	2078	C	LEU	235	−24.612	−10.549	2.478
ATOM	2079	O	LEU	235	−24.003	−9.933	3.338
ATOM	2080	CB	LEU	235	−23.401	−11.823	0.734
ATOM	2081	CG	LEU	235	−22.263	−10.756	0.711
ATOM	2082	CD1	LEU	235	−21.158	−11.055	1.761
ATOM	2083	CD2	LEU	235	−21.637	−10.683	−0.71
ATOM	2084	HA	LEU	235	−23.52	−12.362	2.859
ATOM	2085	H	LEU	235	−25.502	−13.288	1.064
ATOM	2086	HB1	LEU	235	−22.992	−12.812	0.472
ATOM	2087	HB2	LEU	235	−24.127	−11.541	−0.044
ATOM	2088	HG	LEU	235	−22.689	−9.759	0.922
ATOM	2089	HD21	LEU	235	−22.404	−10.435	−1.461
ATOM	2090	HD22	LEU	235	−20.858	−9.905	−0.75
ATOM	2091	HD23	LEU	235	−21.182	−11.648	−0.98
ATOM	2092	HD11	LEU	235	−20.742	−12.061	1.601
ATOM	2093	HD12	LEU	235	−20.341	−10.322	1.674
ATOM	2094	HD13	LEU	235	−21.55	−10.994	2.786
ATOM	2095	N	LEU	236	−25.67	−10.021	1.834
ATOM	2096	CA	LEU	236	−26.039	−8.626	2.062
ATOM	2097	C	LEU	236	−26.486	−8.43	3.492
ATOM	2098	O	LEU	236	−26.058	−7.476	4.125
ATOM	2099	CB	LEU	236	−27.125	−8.211	1.034
ATOM	2100	CG	LEU	236	−26.557	−8.211	−0.424
ATOM	2101	CD1	LEU	236	−27.703	−8.349	−1.455
ATOM	2102	CD2	LEU	236	−25.727	−6.932	−0.703
ATOM	2103	HA	LEU	236	−25.147	−7.997	1.923
ATOM	2104	H	LEU	236	−26.2	−10.58	1.191
ATOM	2105	HB1	LEU	236	−27.961	−8.921	1.122
ATOM	2106	HB2	LEU	236	−27.522	−7.216	1.29
ATOM	2107	HG	LEU	236	−25.873	−9.056	−0.599
ATOM	2108	HD21	LEU	236	−24.788	−6.967	−0.138
ATOM	2109	HD22	LEU	236	−25.465	−6.831	−1.764
ATOM	2110	HD23	LEU	236	−26.303	−6.048	−0.404
ATOM	2111	HD11	LEU	236	−28.413	−7.533	−1.316
ATOM	2112	HD12	LEU	236	−27.307	−8.302	−2.475
ATOM	2113	HD13	LEU	236	−28.241	−9.3	−1.346
ATOM	2114	N	TRP	237	−27.33	−9.332	4.039
ATOM	2115	CA	TRP	237	−27.636	−9.237	5.466
ATOM	2116	C	TRP	237	−26.358	−9.349	6.266
ATOM	2117	O	TRP	237	−26.216	−8.611	7.227
ATOM	2118	CB	TRP	237	−28.639	−10.317	5.958
ATOM	2119	CG	TRP	237	−30.042	−9.785	5.849
ATOM	2120	CD1	TRP	237	−30.958	−10.032	4.901
ATOM	2121	CD2	TRP	237	−30.675	−8.837	6.835
ATOM	2122	NE1	TRP	237	−32.057	−9.372	5.173
ATOM	2123	CE2	TRP	237	−31.945	−8.669	6.317
ATOM	2124	CE3	TRP	237	−30.251	−8.206	8.003
ATOM	2125	CZ2	TRP	237	−32.894	−7.879	6.965
ATOM	2126	CZ3	TRP	237	−31.193	−7.407	8.661
ATOM	2127	CH2	TRP	237	−32.488	−7.236	8.143
ATOM	2128	HA	TRP	237	−28.055	−8.236	5.668
ATOM	2129	H	TRP	237	−27.694	−10.095	3.496
ATOM	2130	HB1	TRP	237	−28.515	−11.258	5.401
ATOM	2131	HB2	TRP	237	−28.48	−10.54	7.026
ATOM	2132	HE1	TRP	237	−32.905	−9.383	4.581
ATOM	2133	HD1	TRP	237	−30.779	−10.681	4.049
ATOM	2134	HZ2	TRP	237	−33.9	−7.772	6.574
ATOM	2135	HH2	TRP	237	−33.182	−6.589	8.667
ATOM	2136	HZ3	TRP	237	−30.918	−6.912	9.586
ATOM	2137	HE3	TRP	237	−29.241	−8.331	8.379
ATOM	2138	N	ALA	238	−25.412	−10.247	5.914
ATOM	2139	CA	ALA	238	−24.179	−10.319	6.697
ATOM	2140	C	ALA	238	−23.466	−8.983	6.681
ATOM	2141	O	ALA	238	−23.053	−8.516	7.731
ATOM	2142	CB	ALA	238	−23.211	−11.42	6.191
ATOM	2143	HA	ALA	238	−24.45	−10.569	7.736
ATOM	2144	H	ALA	238	−25.538	−10.862	5.129
ATOM	2145	HB1	ALA	238	−22.333	−11.482	6.852
ATOM	2146	HB2	ALA	238	−23.72	−12.397	6.186
ATOM	2147	HB3	ALA	238	−22.861	−11.201	5.173
ATOM	2148	N	LEU	239	−23.305	−8.341	5.502
ATOM	2149	CA	LEU	239	−22.592	−7.062	5.461
ATOM	2150	C	LEU	239	−23.313	−6.036	6.309
ATOM	2151	O	LEU	239	−22.67	−5.297	7.04
ATOM	2152	CB	LEU	239	−22.443	−6.505	4.017
ATOM	2153	CG	LEU	239	−21.569	−7.374	3.06
ATOM	2154	CD1	LEU	239	−21.653	−6.805	1.616
ATOM	2155	CD2	LEU	239	−20.081	−7.442	3.506
ATOM	2156	HA	LEU	239	−21.595	−7.195	5.904
ATOM	2157	H	LEU	239	−23.688	−8.727	4.659
ATOM	2158	HB1	LEU	239	−23.455	−6.391	3.594
ATOM	2159	HB2	LEU	239	−21.984	−5.508	4.072
ATOM	2160	HG	LEU	239	−21.962	−8.402	3.032
ATOM	2161	HD21	LEU	239	−19.966	−7.992	4.451
ATOM	2162	HD22	LEU	239	−19.479	−7.968	2.748
ATOM	2163	HD23	LEU	239	−19.67	−6.429	3.632
ATOM	2164	HD11	LEU	239	−21.258	−5.778	1.583
ATOM	2165	HD12	LEU	239	−21.073	−7.427	0.916
ATOM	2166	HD13	LEU	239	−22.697	−6.791	1.271
ATOM	2167	N	SER	240	−24.659	−5.963	6.235
ATOM	2168	CA	SER	240	−25.368	−4.999	7.076
ATOM	2169	C	SER	240	−25.21	−5.355	8.535
ATOM	2170	O	SER	240	−24.871	−4.5	9.337
ATOM	2171	CB	SER	240	−26.868	−4.932	6.707
ATOM	2172	OG	SER	240	−27.527	−3.888	7.443
ATOM	2173	HA	SER	240	−24.954	−3.992	6.909
ATOM	2174	H	SER	240	−25.18	−6.576	5.631
ATOM	2175	HB1	SER	240	−26.925	−4.685	5.638
ATOM	2176	HB2	SER	240	−27.371	−5.902	6.861
ATOM	2177	HG	SER	240	−27.591	−4.092	8.372
ATOM	2178	N	PHE	241	−25.445	−6.63	8.905
ATOM	2179	CA	PHE	241	−25.27	−7.03	10.299
ATOM	2180	C	PHE	241	−23.888	−6.642	10.775
ATOM	2181	O	PHE	241	−23.763	−6.123	11.873
ATOM	2182	CB	PHE	241	−25.467	−8.561	10.44
ATOM	2183	CG	PHE	241	−25.273	−9.014	11.891
ATOM	2184	CD1	PHE	241	−26.302	−8.839	12.823
ATOM	2185	CD2	PHE	241	−24.075	−9.617	12.293
ATOM	2186	CE1	PHE	241	−26.161	−9.321	14.128
ATOM	2187	CE2	PHE	241	−23.945	−10.126	13.588
ATOM	2188	CZ	PHE	241	−24.988	−9.979	14.506
ATOM	2189	HA	PHE	241	−26.024	−6.509	10.913
ATOM	2190	H	PHE	241	−25.723	−7.313	8.227
ATOM	2191	HB1	PHE	241	−26.482	−8.836	10.113
ATOM	2192	HB2	PHE	241	−24.755	−9.084	9.784
ATOM	2193	HD2	PHE	241	−23.242	−9.696	11.601
ATOM	2194	HE2	PHE	241	−23.031	−10.634	13.88
ATOM	2195	HZ	PHE	241	−24.886	−10.374	15.512
ATOM	2196	HE1	PHE	241	−26.963	−9.184	14.847
ATOM	2197	HD1	PHE	241	−27.216	−8.33	12.535
ATOM	2198	N	ILE	242	−22.838	−6.871	9.954
ATOM	2199	CA	ILE	242	−21.49	−6.453	10.347
ATOM	2200	C	ILE	242	−21.455	−4.948	10.501
ATOM	2201	O	ILE	242	−20.829	−4.467	11.431
ATOM	2202	CB	ILE	242	−20.417	−6.936	9.32
ATOM	2203	CG1	ILE	242	−20.27	−8.488	9.403
ATOM	2204	CG2	ILE	242	−19.05	−6.225	9.553
ATOM	2205	CD1	ILE	242	−19.607	−9.118	8.147
ATOM	2206	HA	ILE	242	−21.252	−6.895	11.328
ATOM	2207	H	ILE	242	−22.982	−7.288	9.053
ATOM	2208	HB	ILE	242	−20.763	−6.654	8.313
ATOM	2209	HG11	ILE	242	−19.686	−8.754	10.299
ATOM	2210	HG12	ILE	242	−21.26	−8.958	9.512
ATOM	2211	HD11	ILE	242	−18.574	−8.768	8.01
ATOM	2212	HD12	ILE	242	−19.582	−10.215	8.251
ATOM	2213	HD13	ILE	242	−20.186	−8.874	7.244
ATOM	2214	HG21	ILE	242	−18.7	−6.403	10.582
ATOM	2215	HG22	ILE	242	−18.283	−6.59	8.856
ATOM	2216	HG23	ILE	242	−19.132	−5.138	9.397
ATOM	2217	N	SER	243	−22.103	−4.167	9.612
ATOM	2218	CA	SER	243	−22.092	−2.715	9.795
ATOM	2219	C	SER	243	−22.776	−2.304	11.086
ATOM	2220	O	SER	243	−22.282	−1.398	11.738
ATOM	2221	CB	SER	243	−22.764	−1.99	8.595
ATOM	2222	OG	SER	243	−22.837	−0.566	8.783
ATOM	2223	HA	SER	243	−21.042	−2.378	9.838
ATOM	2224	H	SER	243	−22.596	−4.567	8.835
ATOM	2225	HB1	SER	243	−22.216	−2.218	7.667
ATOM	2226	HB2	SER	243	−23.796	−2.345	8.473
ATOM	2227	HG	SER	243	−21.983	−0.163	8.899
ATOM	2228	N	ILE	244	−23.914	−2.93	11.473
ATOM	2229	CA	ILE	244	−24.678	−2.453	12.637
ATOM	2230	C	ILE	244	−24.275	−3.112	13.94
ATOM	2231	O	ILE	244	−24.13	−2.407	14.928
ATOM	2232	CB	ILE	244	−26.218	−2.62	12.409
ATOM	2233	CG1	ILE	244	−26.782	−1.468	11.526
ATOM	2234	CG2	ILE	244	−27.024	−2.642	13.743
ATOM	2235	CD1	ILE	244	−26.093	−1.335	10.146
ATOM	2236	HA	ILE	244	−24.496	−1.376	12.787
ATOM	2237	H	ILE	244	−24.258	−3.71	10.944
ATOM	2238	HB	ILE	244	−26.412	−3.584	11.91
ATOM	2239	HG11	ILE	244	−27.857	−1.632	11.36
ATOM	2240	HG12	ILE	244	−26.663	−0.52	12.07
ATOM	2241	HD11	ILE	244	−26.115	−2.292	9.609
ATOM	2242	HD12	ILE	244	−26.623	−0.589	9.541
ATOM	2243	HD13	ILE	244	−25.054	−0.994	10.254
ATOM	2244	HG21	ILE	244	−26.82	−1.734	14.332
ATOM	2245	HG22	ILE	244	−28.104	−2.688	13.538
ATOM	2246	HG23	ILE	244	−26.773	−3.523	14.354
ATOM	2247	N	THR	245	−24.117	−4.452	14.012
ATOM	2248	CA	THR	245	−23.98	−5.075	15.33
ATOM	2249	C	THR	245	−22.861	−4.527	16.196
ATOM	2250	O	THR	245	−23.101	−4.441	17.392
ATOM	2251	CB	THR	245	−23.988	−6.634	15.347
ATOM	2252	OG1	THR	245	−24.333	−7.046	16.685
ATOM	2253	CG2	THR	245	−22.638	−7.28	14.935
ATOM	2254	HA	THR	245	−24.916	−4.804	15.849
ATOM	2255	H	THR	245	−24.185	−5.031	13.197
ATOM	2256	HB	THR	245	−24.782	−6.979	14.662
ATOM	2257	HG1	THR	245	−24.433	−7.987	16.782
ATOM	2258	HG23	THR	245	−22.652	−8.357	15.152
ATOM	2259	HG21	THR	245	−22.458	−7.162	13.857
ATOM	2260	HG22	THR	245	−21.8	−6.844	15.497
ATOM	2261	N	PRO	246	−21.648	−4.139	15.719
ATOM	2262	CA	PRO	246	−20.603	−3.715	16.645
ATOM	2263	C	PRO	246	−21.047	−2.748	17.712
ATOM	2264	O	PRO	246	−20.523	−2.787	18.813
ATOM	2265	CB	PRO	246	−19.64	−3.031	15.644
ATOM	2266	CG	PRO	246	−19.793	−3.899	14.375
ATOM	2267	CD	PRO	246	−21.324	−4.097	14.298
ATOM	2268	HA	PRO	246	−20.134	−4.606	17.092
ATOM	2269	HD2	PRO	246	−21.593	−4.997	13.733
ATOM	2270	HD1	PRO	246	−21.757	−3.204	13.822
ATOM	2271	HG2	PRO	246	−19.299	−4.872	14.535
ATOM	2272	HG1	PRO	246	−19.368	−3.425	13.474
ATOM	2273	HB1	PRO	246	−19.991	−2.009	15.419
ATOM	2274	HB2	PRO	246	−18.603	−2.973	16.004
ATOM	2275	N	VAL	247	−22.017	−1.861	17.411
ATOM	2276	CA	VAL	247	−22.409	−0.88	18.413
ATOM	2277	C	VAL	247	−23.195	−1.592	19.484
ATOM	2278	O	VAL	247	−22.865	−1.458	20.651
ATOM	2279	CB	VAL	247	−23.292	0.278	17.878
ATOM	2280	CG1	VAL	247	−23.385	1.398	18.953
ATOM	2281	CG2	VAL	247	−22.774	0.875	16.544
ATOM	2282	HA	VAL	247	−21.496	−0.444	18.849
ATOM	2283	H	VAL	247	−22.496	−1.906	16.534
ATOM	2284	HB	VAL	247	−24.301	−0.118	17.686
ATOM	2285	HG11	VAL	247	−22.394	1.816	19.164
ATOM	2286	HG12	VAL	247	−24.007	2.22	18.587
ATOM	2287	HG13	VAL	247	−23.813	1.022	19.895
ATOM	2288	HG21	VAL	247	−22.777	0.167	15.704
ATOM	2289	HG22	VAL	247	−23.453	1.687	16.271
ATOM	2290	HG23	VAL	247	−21.758	1.274	16.663
ATOM	2291	N	TRP	248	−24.245	−2.355	19.108
ATOM	2292	CA	TRP	248	−25.029	−3.049	20.125
ATOM	2293	C	TRP	248	−24.138	−4.014	20.87
ATOM	2294	O	TRP	248	−24.355	−4.216	22.054
ATOM	2295	CB	TRP	248	−26.232	−3.796	19.495
ATOM	2296	CG	TRP	248	−27.048	−4.503	20.547
ATOM	2297	CD1	TRP	248	−27.198	−5.828	20.693
ATOM	2298	CD2	TRP	248	−27.855	−3.844	21.636
ATOM	2299	NE1	TRP	248	−27.987	−6.067	21.71
ATOM	2300	CE2	TRP	248	−28.402	−4.928	22.297
ATOM	2301	CE3	TRP	248	−28.113	−2.532	22.039
ATOM	2302	CZ2	TRP	248	−29.245	−4.772	23.397
ATOM	2303	CZ3	TRP	248	−28.933	−2.363	23.162
ATOM	2304	CH2	TRP	248	−29.505	−3.462	23.819
ATOM	2305	HA	TRP	248	−25.403	−2.301	20.841
ATOM	2306	H	TRP	248	−24.475	−2.492	18.141
ATOM	2307	HB1	TRP	248	−26.884	−3.079	18.971
ATOM	2308	HB2	TRP	248	−25.855	−4.524	18.759
ATOM	2309	HE1	TRP	248	−28.253	−7.011	22.025
ATOM	2310	HD1	TRP	248	−26.734	−6.584	20.059
ATOM	2311	HZ2	TRP	248	−29.678	−5.629	23.901
ATOM	2312	HH2	TRP	248	−30.159	−3.295	24.669
ATOM	2313	HZ3	TRP	248	−29.13	−1.362	23.534
ATOM	2314	HE3	TRP	248	−27.696	−1.686	21.505
ATOM	2315	N	LEU	249	−23.12	−4.615	20.213
ATOM	2316	CA	LEU	249	−22.182	−5.444	20.963
ATOM	2317	C	LEU	249	−21.392	−4.591	21.935
ATOM	2318	O	LEU	249	−21.154	−5.06	23.036
ATOM	2319	CB	LEU	249	−21.142	−6.176	20.066
ATOM	2320	CG	LEU	249	−21.725	−7.158	19.005
ATOM	2321	CD1	LEU	249	−20.561	−7.845	18.236
ATOM	2322	CD2	LEU	249	−22.66	−8.23	19.629
ATOM	2323	HA	LEU	249	−22.745	−6.187	21.552
ATOM	2324	H	LEU	249	−22.966	−4.465	19.234
ATOM	2325	HB1	LEU	249	−20.541	−5.413	19.547
ATOM	2326	HB2	LEU	249	−20.471	−6.747	20.728
ATOM	2327	HG	LEU	249	−22.312	−6.595	18.265
ATOM	2328	HD21	LEU	249	−23.584	−7.773	20.015
ATOM	2329	HD22	LEU	249	−22.954	−8.971	18.87
ATOM	2330	HD23	LEU	249	−22.147	−8.755	20.449
ATOM	2331	HD11	LEU	249	−19.95	−8.449	18.925
ATOM	2332	HD12	LEU	249	−20.952	−8.506	17.447
ATOM	2333	HD13	LEU	249	−19.912	−7.094	17.761
ATOM	2334	N	TYR	250	−20.948	−3.367	21.554
ATOM	2335	CA	TYR	250	−19.992	−2.626	22.383
ATOM	2336	C	TYR	250	−20.536	−1.421	23.126
ATOM	2337	O	TYR	250	−20.208	−1.306	24.297
ATOM	2338	CB	TYR	250	−18.79	−2.205	21.493
ATOM	2339	CG	TYR	250	−18.234	−3.364	20.639
ATOM	2340	CD1	TYR	250	−17.788	−3.11	19.336
ATOM	2341	CD2	TYR	250	−18.16	−4.677	21.121
ATOM	2342	CE1	TYR	250	−17.354	−4.152	18.51
ATOM	2343	CE2	TYR	250	−17.777	−5.727	20.281
ATOM	2344	CZ	TYR	250	−17.403	−5.476	18.961
ATOM	2345	OH	TYR	250	−17.082	−6.548	18.123
ATOM	2346	HA	TYR	250	−19.586	−3.274	23.175
ATOM	2347	H	TYR	250	−21.199	−2.979	20.665
ATOM	2348	HB2	TYR	250	−19.137	−1.396	20.83
ATOM	2349	HB1	TYR	250	−17.972	−1.812	22.116
ATOM	2350	HD2	TYR	250	−18.393	−4.913	22.151
ATOM	2351	HE2	TYR	250	−17.77	−6.746	20.653
ATOM	2352	HE1	TYR	250	−16.975	−3.927	17.52
ATOM	2353	HD1	TYR	250	−17.777	−2.096	18.952
ATOM	2354	HH	TYR	250	−16.937	−6.302	17.216
ATOM	2355	N	ALA	251	−21.321	−0.484	22.537
ATOM	2356	CA	ALA	251	−21.668	0.722	23.295
ATOM	2357	C	ALA	251	−22.928	1.456	22.877
ATOM	2358	O	ALA	251	−23.987	0.941	23.201
ATOM	2359	CB	ALA	251	−20.425	1.64	23.378
ATOM	2360	HA	ALA	251	−21.897	0.433	24.335
ATOM	2361	H	ALA	251	−21.623	−0.561	21.586
ATOM	2362	HB1	ALA	251	−20.109	1.891	22.362
ATOM	2363	HB2	ALA	251	−20.64	2.57	23.924
ATOM	2364	HB3	ALA	251	−19.598	1.116	23.874
ATOM	2365	N	ARG	252	−22.9	2.656	22.237
ATOM	2366	CA	ARG	252	−24.087	3.507	22.24
ATOM	2367	C	ARG	252	−24.674	3.717	20.865
ATOM	2368	O	ARG	252	−24.006	4.242	19.988
ATOM	2369	CB	ARG	252	−23.771	4.917	22.81
ATOM	2370	CG	ARG	252	−23.3	4.847	24.286
ATOM	2371	CD	ARG	252	−23.129	6.265	24.898
ATOM	2372	NE	ARG	252	−22.867	6.148	26.337
ATOM	2373	CZ	ARG	252	−23.792	5.873	27.235
ATOM	2374	NH1	ARG	252	−25.055	5.69	26.935
ATOM	2375	NH2	ARG	252	−23.44	5.771	28.496
ATOM	2376	HA	ARG	252	−24.859	3.108	22.917
ATOM	2377	H	ARG	252	−22.091	3.059	21.808
ATOM	2378	HB1	ARG	252	−22.993	5.403	22.204
ATOM	2379	HB2	ARG	252	−24.683	5.534	22.756
ATOM	2380	HG1	ARG	252	−24.028	4.265	24.87
ATOM	2381	HG2	ARG	252	−22.338	4.316	24.346
ATOM	2382	HD1	ARG	252	−22.265	6.74	24.4
ATOM	2383	HD2	ARG	252	−23.986	6.926	24.699
ATOM	2384	HE	ARG	252	−21.893	6.291	26.647
ATOM	2385	HH12	ARG	252	−25.753	5.447	27.659
ATOM	2386	HH11	ARG	252	−25.413	5.763	25.973
ATOM	2387	HH22	ARG	252	−24.135	5.554	29.226
ATOM	2388	HH21	ARG	252	−22.462	5.9	28.792
ATOM	2389	N	LEU	253	−25.961	3.361	20.68
ATOM	2390	CA	LEU	253	−26.729	3.951	19.592
ATOM	2391	C	LEU	253	−27.26	5.195	20.29
ATOM	2392	O	LEU	253	−28.229	5.091	21.024
ATOM	2393	CB	LEU	253	−27.744	2.881	19.103
ATOM	2394	CG	LEU	253	−27.027	1.641	18.467
ATOM	2395	CD1	LEU	253	−27.943	0.397	18.401
ATOM	2396	CD2	LEU	253	−26.472	1.917	17.042
ATOM	2397	HA	LEU	253	−26.104	4.237	18.734
ATOM	2398	H	LEU	253	−26.475	2.853	21.376
ATOM	2399	HB1	LEU	253	−28.358	2.573	19.963
ATOM	2400	HB2	LEU	253	−28.409	3.357	18.377
ATOM	2401	HG	LEU	253	−26.195	1.351	19.128
ATOM	2402	HD21	LEU	253	−27.269	2.23	16.361
ATOM	2403	HD22	LEU	253	−26.02	1.019	16.602
ATOM	2404	HD23	LEU	253	−25.711	2.7	17.066
ATOM	2405	HD11	LEU	253	−28.818	0.592	17.764
ATOM	2406	HD12	LEU	253	−28.262	0.143	19.42
ATOM	2407	HD13	LEU	253	−27.404	−0.472	17.993
ATOM	2408	N	ILE	254	−26.581	6.361	20.135
ATOM	2409	CA	ILE	254	−26.773	7.511	21.033
ATOM	2410	C	ILE	254	−27.984	8.348	20.665
ATOM	2411	O	ILE	254	−28.157	8.541	19.473
ATOM	2412	CB	ILE	254	−25.481	8.406	21.05
ATOM	2413	CG1	ILE	254	−25.395	9.303	22.324
ATOM	2414	CG2	ILE	254	−25.342	9.292	19.775
ATOM	2415	CD1	ILE	254	−24.076	10.117	22.439
ATOM	2416	HA	ILE	254	−26.893	7.075	22.036
ATOM	2417	H	ILE	254	−25.872	6.412	19.432
ATOM	2418	HB	ILE	254	−24.618	7.718	21.088
ATOM	2419	HG11	ILE	254	−26.236	10.017	22.334
ATOM	2420	HG12	ILE	254	−25.452	8.66	23.217
ATOM	2421	HD11	ILE	254	−24.013	10.907	21.672
ATOM	2422	HD12	ILE	254	−24.02	10.601	23.428
ATOM	2423	HD13	ILE	254	−23.214	9.445	22.338
ATOM	2424	HG21	ILE	254	−26.051	10.133	19.812
ATOM	2425	HG22	ILE	254	−24.321	9.69	19.684
ATOM	2426	HG23	ILE	254	−25.54	8.731	18.857
ATOM	2427	N	PRO	255	−28.848	8.876	21.577
ATOM	2428	CA	PRO	255	−29.993	9.666	21.126
ATOM	2429	C	PRO	255	−29.719	11.06	20.594
ATOM	2430	O	PRO	255	−28.608	11.557	20.68
ATOM	2431	CB	PRO	255	−30.842	9.699	22.423
ATOM	2432	CG	PRO	255	−29.78	9.627	23.54
ATOM	2433	CD	PRO	255	−28.786	8.571	23.003
ATOM	2434	HA	PRO	255	−30.543	9.128	20.351
ATOM	2435	HD2	PRO	255	−29.166	7.552	23.182
ATOM	2436	HD1	PRO	255	−27.816	8.693	23.499
ATOM	2437	HG2	PRO	255	−30.204	9.361	24.523
ATOM	2438	HG1	PRO	255	−29.277	10.606	23.616
ATOM	2439	HB1	PRO	255	−31.489	10.586	22.507
ATOM	2440	HB2	PRO	255	−31.468	8.793	22.489
ATOM	2441	N	PHE	256	−30.782	11.69	20.032
ATOM	2442	CA	PHE	256	−30.706	13.035	19.457
ATOM	2443	C	PHE	256	−31.818	13.857	20.074
ATOM	2444	O	PHE	256	−32.807	14.082	19.398
ATOM	2445	CB	PHE	256	−30.87	12.893	17.917
ATOM	2446	CG	PHE	256	−31.068	14.225	17.171
ATOM	2447	CD1	PHE	256	−29.973	15.051	16.898
ATOM	2448	CD2	PHE	256	−32.339	14.624	16.737
ATOM	2449	CE1	PHE	256	−30.146	16.247	16.197
ATOM	2450	CE2	PHE	256	−32.524	15.85	16.093
ATOM	2451	CZ	PHE	256	−31.423	16.662	15.812
ATOM	2452	HA	PHE	256	−29.738	13.522	19.637
ATOM	2453	H	PHE	256	−31.668	11.224	19.966
ATOM	2454	HB1	PHE	256	−29.987	12.369	17.531
ATOM	2455	HB2	PHE	256	−31.733	12.261	17.691
ATOM	2456	HD2	PHE	256	−33.202	13.987	16.894
ATOM	2457	HE2	PHE	256	−33.522	16.169	15.809
ATOM	2458	HZ	PHE	256	−31.559	17.608	15.3
ATOM	2459	HE1	PHE	256	−29.286	16.853	15.949
ATOM	2460	HD1	PHE	256	−28.984	14.766	17.227
ATOM	2461	N	PRO	257	−31.761	14.329	21.343
ATOM	2462	CA	PRO	257	−32.89	15.083	21.881
ATOM	2463	C	PRO	257	−32.874	16.496	21.338
ATOM	2464	O	PRO	257	−32.538	17.414	22.069
ATOM	2465	CB	PRO	257	−32.552	14.984	23.391
ATOM	2466	CG	PRO	257	−31.006	14.984	23.419
ATOM	2467	CD	PRO	257	−30.623	14.086	22.219
ATOM	2468	HA	PRO	257	−33.868	14.617	21.675
ATOM	2469	HD2	PRO	257	−30.594	13.025	22.511
ATOM	2470	HD1	PRO	257	−29.65	14.391	21.804
ATOM	2471	HG2	PRO	257	−30.589	14.624	24.374
ATOM	2472	HG1	PRO	257	−30.644	16.011	23.241
ATOM	2473	HB1	PRO	257	−33.001	15.787	23.997
ATOM	2474	HB2	PRO	257	−32.902	14.015	23.783
ATOM	2475	N	GLY	258	−33.243	16.702	20.052
ATOM	2476	CA	GLY	258	−33.225	18.046	19.468
ATOM	2477	C	GLY	258	−34.627	18.596	19.361
ATOM	2478	O	GLY	258	−34.998	19.058	18.293
ATOM	2479	HA2	GLY	258	−32.781	17.987	18.461
ATOM	2480	HA1	GLY	258	−32.621	18.761	20.047
ATOM	2481	H	GLY	258	−33.555	15.942	19.471
ATOM	2482	N	GLY	259	−35.436	18.561	20.445
ATOM	2483	CA	GLY	259	−36.844	18.939	20.316
ATOM	2484	C	GLY	259	−37.509	17.812	19.565
ATOM	2485	O	GLY	259	−38.196	17.011	20.178
ATOM	2486	HA2	GLY	259	−36.96	19.89	19.773
ATOM	2487	HA1	GLY	259	−37.317	19.057	21.305
ATOM	2488	H	GLY	259	−35.111	18.193	21.319
ATOM	2489	N	ALA	260	−37.264	17.708	18.24
ATOM	2490	CA	ALA	260	−37.568	16.46	17.544
ATOM	2491	C	ALA	260	−36.582	15.423	18.035
ATOM	2492	O	ALA	260	−35.611	15.805	18.67
ATOM	2493	CB	ALA	260	−37.438	16.636	16.013
ATOM	2494	HA	ALA	260	−38.592	16.131	17.787
ATOM	2495	HB1	ALA	260	−38.145	17.402	15.668
ATOM	2496	HB2	ALA	260	−36.413	16.946	15.757
ATOM	2497	HB3	ALA	260	−37.661	15.698	15.492
ATOM	2498	H	ALA	260	−36.723	18.404	17.763
ATOM	2499	N	VAL	261	−36.812	14.111	17.784
ATOM	2500	CA	VAL	261	−36.022	13.084	18.466
ATOM	2501	C	VAL	261	−35.515	12.025	17.506
ATOM	2502	O	VAL	261	−36.147	11.79	16.489
ATOM	2503	CB	VAL	261	−36.9	12.49	19.605
ATOM	2504	CG1	VAL	261	−36.115	11.465	20.466
ATOM	2505	CG2	VAL	261	−37.458	13.626	20.511
ATOM	2506	HA	VAL	261	−35.137	13.529	18.939
ATOM	2507	HB	VAL	261	−37.748	11.965	19.134
ATOM	2508	HG11	VAL	261	−35.215	11.94	20.884
ATOM	2509	HG12	VAL	261	−36.727	11.096	21.301
ATOM	2510	HG13	VAL	261	−35.827	10.595	19.856
ATOM	2511	HG21	VAL	261	−38.149	14.274	19.952
ATOM	2512	HG22	VAL	261	−38.015	13.214	21.364
ATOM	2513	HG23	VAL	261	−36.635	14.242	20.904
ATOM	2514	H	VAL	261	−37.58	13.806	17.218
ATOM	2515	N	GLY	262	−34.367	11.373	17.805
ATOM	2516	CA	GLY	262	−33.827	10.356	16.902
ATOM	2517	C	GLY	262	−32.552	9.773	17.467
ATOM	2518	O	GLY	262	−32.345	9.955	18.656
ATOM	2519	HA2	GLY	262	−33.622	10.806	15.92
ATOM	2520	HA1	GLY	262	−34.554	9.54	16.782
ATOM	2521	H	GLY	262	−33.863	11.566	18.649
ATOM	2522	N	CYS	263	−31.688	9.086	16.68
ATOM	2523	CA	CYS	263	−30.496	8.474	17.272
ATOM	2524	C	CYS	263	−29.377	8.187	16.289
ATOM	2525	O	CYS	263	−29.67	8.08	15.109
ATOM	2526	CB	CYS	263	−30.89	7.095	17.849
ATOM	2527	SG	CYS	263	−31.975	7.135	19.301
ATOM	2528	HA	CYS	263	−30.084	9.143	18.04
ATOM	2529	HB1	CYS	263	−31.41	6.533	17.061
ATOM	2530	HB2	CYS	263	−29.967	6.584	18.161
ATOM	2531	LPG1	CYS	263	−32.17	7.769	19.447
ATOM	2532	LPG2	CYS	263	−32.523	6.745	19.21
ATOM	2533	H	CYS	263	−31.869	8.932	15.707
ATOM	2534	N	GLY	264	−28.109	8.03	16.764
ATOM	2535	CA	GLY	264	−26.981	7.764	15.865
ATOM	2536	C	GLY	264	−25.877	6.946	16.505
ATOM	2537	O	GLY	264	−25.924	6.676	17.691
ATOM	2538	HA2	GLY	264	−26.531	8.712	15.539
ATOM	2539	HA1	GLY	264	−27.313	7.202	14.977
ATOM	2540	H	GLY	264	−27.904	8.112	17.745
ATOM	2541	N	ILE	265	−24.838	6.541	15.743
ATOM	2542	CA	ILE	265	−23.909	5.507	16.221
ATOM	2543	C	ILE	265	−22.695	6.041	16.968
ATOM	2544	O	ILE	265	−21.96	6.797	16.355
ATOM	2545	CB	ILE	265	−23.537	4.56	15.024
ATOM	2546	CG1	ILE	265	−24.823	4.055	14.29
ATOM	2547	CG2	ILE	265	−22.554	5.185	13.999
ATOM	2548	CD1	ILE	265	−24.617	2.805	13.387
ATOM	2549	HA	ILE	265	−24.442	4.861	16.936
ATOM	2550	HB	ILE	265	−22.988	3.711	15.453
ATOM	2551	HG11	ILE	265	−25.582	3.793	15.037
ATOM	2552	HG12	ILE	265	−25.25	4.859	13.669
ATOM	2553	HD11	ILE	265	−24.105	2.001	13.934
ATOM	2554	HD12	ILE	265	−25.592	2.419	13.05
ATOM	2555	HD13	ILE	265	−24.032	3.041	12.487
ATOM	2556	HG21	ILE	265	−22.361	4.504	13.163
ATOM	2557	HG22	ILE	265	−22.969	6.104	13.573
ATOM	2558	HG23	ILE	265	−21.583	5.395	14.469
ATOM	2559	H	ILE	265	−24.728	6.916	14.825
ATOM	2560	N	ARG	266	−22.394	5.665	18.246
ATOM	2561	CA	ARG	266	−21.137	6.086	18.884
ATOM	2562	C	ARG	266	−20.476	4.966	19.685
ATOM	2563	O	ARG	266	−21.151	4.306	20.458
ATOM	2564	CB	ARG	266	−21.438	7.316	19.782
ATOM	2565	CG	ARG	266	−20.133	8.016	20.248
ATOM	2566	CD	ARG	266	−20.406	9.299	21.079
ATOM	2567	NE	ARG	266	−19.188	10.098	21.237
ATOM	2568	CZ	ARG	266	−19.155	11.317	21.729
ATOM	2569	NH1	ARG	266	−20.223	11.934	22.172
ATOM	2570	NH2	ARG	266	−18.003	11.942	21.786
ATOM	2571	HA	ARG	266	−20.425	6.393	18.103
ATOM	2572	H	ARG	266	−22.981	5.096	18.825
ATOM	2573	HB1	ARG	266	−22.042	8.025	19.191
ATOM	2574	HB2	ARG	266	−22.033	7.007	20.654
ATOM	2575	HG1	ARG	266	−19.5	7.323	20.828
ATOM	2576	HG2	ARG	266	−19.589	8.311	19.342
ATOM	2577	HD1	ARG	266	−21.161	9.877	20.528
ATOM	2578	HD2	ARG	266	−20.802	9.013	22.066
ATOM	2579	HE	ARG	266	−18.306	9.671	20.922
ATOM	2580	HH12	ARG	266	−20.16	12.89	22.548
ATOM	2581	HH11	ARG	266	−21.145	11.484	22.171
ATOM	2582	HH22	ARG	266	−17.128	11.505	21.456
ATOM	2583	HH21	ARG	266	−17.916	12.893	22.173
ATOM	2584	N	LEU	267	−19.148	4.706	19.533
ATOM	2585	CA	LEU	267	−18.505	3.536	20.17
ATOM	2586	C	LEU	267	−18.369	3.72	21.677
ATOM	2587	O	LEU	267	−18.978	4.657	22.169
ATOM	2588	CB	LEU	267	−19.172	2.199	19.711
ATOM	2589	CG	LEU	267	−18.951	1.79	18.223
ATOM	2590	CD1	LEU	267	−19.432	2.868	17.214
ATOM	2591	CD2	LEU	267	−17.484	1.363	17.939
ATOM	2592	HA	LEU	267	−17.456	3.517	19.837
ATOM	2593	H	LEU	267	−18.571	5.308	18.975
ATOM	2594	HB1	LEU	267	−18.81	1.35	20.296
ATOM	2595	HB2	LEU	267	−20.246	2.239	19.905
ATOM	2596	HG	LEU	267	−19.568	0.888	18.052
ATOM	2597	HD21	LEU	267	−17.414	0.929	16.932
ATOM	2598	HD22	LEU	267	−17.152	0.6	18.66
ATOM	2599	HD23	LEU	267	−16.794	2.217	17.993
ATOM	2600	HD11	LEU	267	−19.508	2.42	16.213
ATOM	2601	HD12	LEU	267	−20.424	3.255	17.492
ATOM	2602	HD13	LEU	267	−18.723	3.705	17.158
ATOM	2603	N	PRO	268	−17.584	2.938	22.48
ATOM	2604	CA	PRO	268	−17.3	3.369	23.849
ATOM	2605	C	PRO	268	−16.26	4.459	23.748
ATOM	2606	O	PRO	268	−16.058	4.93	22.641
ATOM	2607	CB	PRO	268	−16.627	2.082	24.397
ATOM	2608	CG	PRO	268	−15.855	1.558	23.166
ATOM	2609	CD	PRO	268	−16.881	1.739	22.024
ATOM	2610	HA	PRO	268	−18.185	3.684	24.424
ATOM	2611	HD2	PRO	268	−17.544	0.86	22.06
ATOM	2612	HD1	PRO	268	−16.376	1.813	21.049
ATOM	2613	HG2	PRO	268	−15.51	0.517	23.282
ATOM	2614	HG1	PRO	268	−14.978	2.202	22.987
ATOM	2615	HB1	PRO	268	−15.967	2.234	25.264
ATOM	2616	HB2	PRO	268	−17.393	1.346	24.683
ATOM	2617	N	ASN	269	−15.559	4.856	24.839
ATOM	2618	CA	ASN	269	−14.345	5.663	24.658
ATOM	2619	C	ASN	269	−14.725	6.818	23.756
ATOM	2620	O	ASN	269	−14.208	6.929	22.655
ATOM	2621	CB	ASN	269	−13.308	4.681	24.043
ATOM	2622	CG	ASN	269	−11.857	5.025	24.254
ATOM	2623	OD1	ASN	269	−11.546	5.969	24.963
ATOM	2624	ND2	ASN	269	−10.936	4.238	23.659
ATOM	2625	HA	ASN	269	−13.961	6.017	25.627
ATOM	2626	HB1	ASN	269	−13.427	3.702	24.534
ATOM	2627	HB2	ASN	269	−13.516	4.545	22.975
ATOM	2628	HD22	ASN	269	−9.963	4.391	23.829
ATOM	2629	HD21	ASN	269	−11.213	3.506	23.029
ATOM	2630	H	ASN	269	−15.785	4.53	25.758
ATOM	2631	N	PRO	270	−15.711	7.652	24.166
ATOM	2632	CA	PRO	270	−16.597	8.264	23.185
ATOM	2633	C	PRO	270	−15.979	9.108	22.101
ATOM	2634	O	PRO	270	−16.693	9.362	21.145
ATOM	2635	CB	PRO	270	−17.538	9.072	24.117
ATOM	2636	CG	PRO	270	−16.753	9.197	25.442
ATOM	2637	CD	PRO	270	−16.046	7.83	25.57
ATOM	2638	HA	PRO	270	−17.161	7.46	22.68
ATOM	2639	HD2	PRO	270	−16.737	7.045	25.914
ATOM	2640	HD1	PRO	270	−15.181	7.912	26.247
ATOM	2641	HG2	PRO	270	−17.393	9.433	26.308
ATOM	2642	HG1	PRO	270	−15.994	9.991	25.331
ATOM	2643	HB1	PRO	270	−17.814	10.059	23.719
ATOM	2644	HB2	PRO	270	−18.461	8.499	24.309
ATOM	2645	N	ASP	271	−14.714	9.563	22.189
ATOM	2646	CA	ASP	271	−14.149	10.389	21.118
ATOM	2647	C	ASP	271	−13.151	9.641	20.255
ATOM	2648	O	ASP	271	−13.116	9.897	19.061
ATOM	2649	CB	ASP	271	−13.576	11.668	21.773
ATOM	2650	CG	ASP	271	−14.719	12.323	22.508
ATOM	2651	OD1	ASP	271	−15.677	12.781	21.826
ATOM	2652	OD2	ASP	271	−14.689	12.367	23.765
ATOM	2653	HA	ASP	271	−14.926	10.746	20.422
ATOM	2654	HB1	ASP	271	−12.76	11.408	22.465
ATOM	2655	HB2	ASP	271	−13.184	12.356	21.008
ATOM	2656	H	ASP	271	−14.162	9.367	23.001
ATOM	2657	N	THR	272	−12.326	8.714	20.791
ATOM	2658	CA	THR	272	−11.335	8.043	19.949
ATOM	2659	C	THR	272	−11.98	6.911	19.18
ATOM	2660	O	THR	272	−11.983	6.962	17.959
ATOM	2661	CB	THR	272	−10.179	7.512	20.835
ATOM	2662	OG1	THR	272	−10.793	6.777	21.904
ATOM	2663	CG2	THR	272	−9.337	8.68	21.417
ATOM	2664	HA	THR	272	−10.9	8.751	19.223
ATOM	2665	HB	THR	272	−9.528	6.852	20.234
ATOM	2666	HG1	THR	272	−10.152	6.426	22.511
ATOM	2667	HG23	THR	272	−8.881	9.271	20.609
ATOM	2668	HG21	THR	272	−9.97	9.342	22.028
ATOM	2669	HG22	THR	272	−8.53	8.284	22.054
ATOM	2670	H	THR	272	−12.389	8.436	21.751
ATOM	2671	N	ASP	273	−12.535	5.878	19.856
ATOM	2672	CA	ASP	273	−13.207	4.808	19.114
ATOM	2673	C	ASP	273	−14.22	5.412	18.167
ATOM	2674	O	ASP	273	−14.333	4.935	17.049
ATOM	2675	CB	ASP	273	−13.937	3.782	20.018
ATOM	2676	CG	ASP	273	−12.973	2.988	20.858
ATOM	2677	OD1	ASP	273	−13.257	1.788	21.117
ATOM	2678	OD2	ASP	273	−11.925	3.552	21.27
ATOM	2679	HA	ASP	273	−12.448	4.264	18.527
ATOM	2680	H	ASP	273	−12.484	5.818	20.857
ATOM	2681	HB1	ASP	273	−14.507	3.081	19.386
ATOM	2682	HB2	ASP	273	−14.647	4.306	20.674
ATOM	2683	N	LEU	274	−14.957	6.468	18.577
ATOM	2684	CA	LEU	274	−15.831	7.159	17.626
ATOM	2685	C	LEU	274	−15.031	7.58	16.417
ATOM	2686	O	LEU	274	−15.4	7.227	15.307
ATOM	2687	CB	LEU	274	−16.476	8.431	18.25
ATOM	2688	CG	LEU	274	−17.069	9.454	17.231
ATOM	2689	CD1	LEU	274	−18.169	8.831	16.33
ATOM	2690	CD2	LEU	274	−17.634	10.701	17.97
ATOM	2691	HA	LEU	274	−16.627	6.463	17.31
ATOM	2692	H	LEU	274	−14.884	6.807	19.519
ATOM	2693	HB1	LEU	274	−15.695	8.965	18.81
ATOM	2694	HB2	LEU	274	−17.241	8.104	18.968
ATOM	2695	HG	LEU	274	−16.261	9.828	16.579
ATOM	2696	HD21	LEU	274	−16.874	11.145	18.631
ATOM	2697	HD22	LEU	274	−17.943	11.47	17.244
ATOM	2698	HD23	LEU	274	−18.511	10.431	18.573
ATOM	2699	HD11	LEU	274	−19.007	8.459	16.937
ATOM	2700	HD12	LEU	274	−18.551	9.599	15.64
ATOM	2701	HD13	LEU	274	−17.784	7.998	15.725
ATOM	2702	N	TYR	275	−13.944	8.359	16.615
ATOM	2703	CA	TYR	275	−13.236	8.908	15.462
ATOM	2704	C	TYR	275	−12.873	7.793	14.508
ATOM	2705	O	TYR	275	−13.114	7.907	13.316
ATOM	2706	CB	TYR	275	−11.962	9.693	15.877
ATOM	2707	CG	TYR	275	−11.399	10.437	14.659
ATOM	2708	CD1	TYR	275	−11.689	11.792	14.458
ATOM	2709	CD2	TYR	275	−10.598	9.764	13.73
ATOM	2710	CE1	TYR	275	−11.248	12.448	13.305
ATOM	2711	CE2	TYR	275	−10.156	10.421	12.578
ATOM	2712	CZ	TYR	275	−10.489	11.759	12.351
ATOM	2713	OH	TYR	275	−10.054	12.381	11.177
ATOM	2714	HA	TYR	275	−13.923	9.606	14.96
ATOM	2715	H	TYR	275	−13.63	8.598	17.537
ATOM	2716	HB2	TYR	275	−11.203	9.011	16.291
ATOM	2717	HB1	TYR	275	−12.217	10.422	16.662
ATOM	2718	HD2	TYR	275	−10.318	8.729	13.897
ATOM	2719	HE2	TYR	275	−9.551	9.89	11.85
ATOM	2720	HE1	TYR	275	−11.505	13.493	13.158
ATOM	2721	HD1	TYR	275	−12.265	12.344	15.194
ATOM	2722	HH	TYR	275	−10.35	13.279	11.079
ATOM	2723	N	TRP	276	−12.294	6.691	15.033
ATOM	2724	CA	TRP	276	−11.946	5.575	14.157
ATOM	2725	C	TRP	276	−13.19	4.932	13.583
ATOM	2726	O	TRP	276	−13.185	4.565	12.417
ATOM	2727	CB	TRP	276	−11.129	4.506	14.93
ATOM	2728	CG	TRP	276	−10.814	3.347	14.02
ATOM	2729	CD1	TRP	276	−9.764	3.229	13.192
ATOM	2730	CD2	TRP	276	−11.64	2.095	13.868
ATOM	2731	NE1	TRP	276	−9.84	2.09	12.554
ATOM	2732	CE2	TRP	276	−10.933	1.388	12.913
ATOM	2733	CE3	TRP	276	−12.811	1.601	14.441
ATOM	2734	CZ2	TRP	276	−11.365	0.144	12.453
ATOM	2735	CZ3	TRP	276	−13.265	0.359	13.974
ATOM	2736	CH2	TRP	276	−12.557	−0.355	12.994
ATOM	2737	HA	TRP	276	−11.324	5.948	13.327
ATOM	2738	H	TRP	276	−12.129	6.617	16.022
ATOM	2739	HB1	TRP	276	−11.691	4.139	15.803
ATOM	2740	HB2	TRP	276	−10.191	4.958	15.291
ATOM	2741	HE1	TRP	276	−9.15	1.769	11.858
ATOM	2742	HD1	TRP	276	−8.977	3.976	13.075
ATOM	2743	HZ2	TRP	276	−10.802	−0.407	11.706
ATOM	2744	HH2	TRP	276	−12.939	−1.311	12.65
ATOM	2745	HZ3	TRP	276	−14.179	−0.06	14.38
ATOM	2746	HE3	TRP	276	−13.338	2.152	15.211
ATOM	2747	N	PHE	277	−14.266	4.765	14.384
ATOM	2748	CA	PHE	277	−15.424	4.032	13.89
ATOM	2749	C	PHE	277	−16.072	4.732	12.726
ATOM	2750	O	PHE	277	−16.412	4.06	11.766
ATOM	2751	CB	PHE	277	−16.518	3.779	14.952
ATOM	2752	CG	PHE	277	−17.578	2.862	14.322
ATOM	2753	CD1	PHE	277	−18.769	3.379	13.797
ATOM	2754	CD2	PHE	277	−17.344	1.484	14.26
ATOM	2755	CE1	PHE	277	−19.721	2.518	13.243
ATOM	2756	CE2	PHE	277	−18.299	0.622	13.716
ATOM	2757	CZ	PHE	277	−19.495	1.139	13.212
ATOM	2758	HA	PHE	277	−15.064	3.049	13.558
ATOM	2759	H	PHE	277	−14.274	5.099	15.327
ATOM	2760	HB1	PHE	277	−16.071	3.285	15.828
ATOM	2761	HB2	PHE	277	−16.955	4.733	15.284
ATOM	2762	HD1	PHE	277	−18.958	4.448	13.814
ATOM	2763	HE1	PHE	277	−20.64	2.914	12.829
ATOM	2764	HZ	PHE	277	−20.246	0.472	12.796
ATOM	2765	HE2	PHE	277	−18.112	−0.448	13.683
ATOM	2766	HD2	PHE	277	−16.413	1.076	14.633
ATOM	2767	N	THR	278	−16.277	6.066	12.765
ATOM	2768	CA	THR	278	−16.88	6.699	11.597
ATOM	2769	C	THR	278	−16.01	6.439	10.392
ATOM	2770	O	THR	278	−16.543	6.077	9.355
ATOM	2771	CB	THR	278	−17.058	8.234	11.726
ATOM	2772	OG1	THR	278	−17.881	8.533	12.864
ATOM	2773	CG2	THR	278	−17.638	8.822	10.407
ATOM	2774	HA	THR	278	−17.878	6.255	11.449
ATOM	2775	H	THR	278	−16.025	6.629	13.56
ATOM	2776	HB	THR	278	−16.079	8.694	11.92
ATOM	2777	HG1	THR	278	−18.759	8.178	12.785
ATOM	2778	HG23	THR	278	−16.903	8.807	9.588
ATOM	2779	HG21	THR	278	−17.953	9.862	10.562
ATOM	2780	HG22	THR	278	−18.506	8.235	10.084
ATOM	2781	N	LEU	279	−14.676	6.634	10.499
ATOM	2782	CA	LEU	279	−13.831	6.394	9.332
ATOM	2783	C	LEU	279	−14.053	4.974	8.862
ATOM	2784	O	LEU	279	−14.311	4.766	7.687
ATOM	2785	CB	LEU	279	−12.332	6.644	9.653
ATOM	2786	CG	LEU	279	−11.351	6.238	8.511
ATOM	2787	CD1	LEU	279	−11.634	7.003	7.187
ATOM	2788	CD2	LEU	279	−9.886	6.499	8.968
ATOM	2789	HA	LEU	279	−14.154	7.091	8.543
ATOM	2790	H	LEU	279	−14.261	6.929	11.363
ATOM	2791	HB1	LEU	279	−12.2	7.711	9.894
ATOM	2792	HB2	LEU	279	−12.068	6.064	10.551
ATOM	2793	HG	LEU	279	−11.449	5.156	8.313
ATOM	2794	HD21	LEU	279	−9.661	5.938	9.889
ATOM	2795	HD22	LEU	279	−9.174	6.18	8.192
ATOM	2796	HD23	LEU	279	−9.731	7.572	9.165
ATOM	2797	HD11	LEU	279	−11.622	8.09	7.364
ATOM	2798	HD12	LEU	279	−10.865	6.763	6.436
ATOM	2799	HD13	LEU	279	−12.609	6.724	6.762
ATOM	2800	N	TYR	280	−13.965	3.984	9.777
ATOM	2801	CA	TYR	280	−14.202	2.595	9.385
ATOM	2802	C	TYR	280	−15.549	2.438	8.714
ATOM	2803	O	TYR	280	−15.613	1.86	7.64
ATOM	2804	CB	TYR	280	−14.142	1.675	10.634
ATOM	2805	CG	TYR	280	−14.699	0.27	10.363
ATOM	2806	CD1	TYR	280	−16.031	−0.028	10.675
ATOM	2807	CD2	TYR	280	−13.882	−0.726	9.819
ATOM	2808	CE1	TYR	280	−16.521	−1.324	10.501
ATOM	2809	CE2	TYR	280	−14.372	−2.024	9.649
ATOM	2810	CZ	TYR	280	−15.689	−2.334	10.012
ATOM	2811	OH	TYR	280	−16.193	−3.634	9.895
ATOM	2812	HA	TYR	280	−13.417	2.28	8.677
ATOM	2813	H	TYR	280	−13.747	4.198	10.734
ATOM	2814	HB2	TYR	280	−13.105	1.624	10.998
ATOM	2815	HB1	TYR	280	−14.745	2.112	11.44
ATOM	2816	HD2	TYR	280	−12.863	−0.492	9.531
ATOM	2817	HE2	TYR	280	−13.722	−2.786	9.234
ATOM	2818	HE1	TYR	280	−17.553	−1.552	10.748
ATOM	2819	HD1	TYR	280	−16.694	0.742	11.056
ATOM	2820	HH	TYR	280	−15.546	−4.285	9.646
ATOM	2821	N	GLN	281	−16.644	2.929	9.332
ATOM	2822	CA	GLN	281	−17.968	2.718	8.753
ATOM	2823	C	GLN	281	−18.071	3.407	7.416
ATOM	2824	O	GLN	281	−18.487	2.779	6.457
ATOM	2825	CB	GLN	281	−19.091	3.272	9.672
ATOM	2826	CG	GLN	281	−20.498	3.103	9.036
ATOM	2827	CD	GLN	281	−21.561	3.703	9.921
ATOM	2828	OE1	GLN	281	−22.321	2.968	10.53
ATOM	2829	NE2	GLN	281	−21.644	5.046	10.015
ATOM	2830	HA	GLN	281	−18.126	1.635	8.62
ATOM	2831	H	GLN	281	−16.561	3.434	10.193
ATOM	2832	HB1	GLN	281	−19.059	2.73	10.629
ATOM	2833	HB2	GLN	281	−18.907	4.337	9.879
ATOM	2834	HG1	GLN	281	−20.562	3.609	8.06
ATOM	2835	HG2	GLN	281	−20.704	2.034	8.874
ATOM	2836	HE22	GLN	281	−22.344	5.454	10.604
ATOM	2837	HE21	GLN	281	−21.023	5.652	9.516
ATOM	2838	N	PHE	282	−17.731	4.709	7.328
ATOM	2839	CA	PHE	282	−17.908	5.406	6.058
ATOM	2840	C	PHE	282	−17.029	4.759	5.014
ATOM	2841	O	PHE	282	−17.486	4.521	3.907
ATOM	2842	CB	PHE	282	−17.567	6.913	6.185
ATOM	2843	CG	PHE	282	−17.868	7.616	4.854
ATOM	2844	CD1	PHE	282	−19.193	7.907	4.512
ATOM	2845	CD2	PHE	282	−16.837	7.967	3.975
ATOM	2846	CE1	PHE	282	−19.488	8.55	3.307
ATOM	2847	CE2	PHE	282	−17.128	8.635	2.782
ATOM	2848	CZ	PHE	282	−18.452	8.938	2.453
ATOM	2849	HA	PHE	282	−18.963	5.306	5.752
ATOM	2850	H	PHE	282	−17.361	5.203	8.116
ATOM	2851	HB1	PHE	282	−18.184	7.368	6.977
ATOM	2852	HB2	PHE	282	−16.511	7.04	6.471
ATOM	2853	HD2	PHE	282	−15.807	7.722	4.213
ATOM	2854	HE2	PHE	282	−16.325	8.919	2.11
ATOM	2855	HZ	PHE	282	−18.677	9.471	1.535
ATOM	2856	HE1	PHE	282	−20.519	8.746	3.034
ATOM	2857	HD1	PHE	282	−19.997	7.629	5.183
ATOM	2858	N	PHE	283	−15.757	4.456	5.35
ATOM	2859	CA	PHE	283	−14.893	3.803	4.372
ATOM	2860	C	PHE	283	−15.482	2.476	3.943
ATOM	2861	O	PHE	283	−15.698	2.263	2.76
ATOM	2862	CB	PHE	283	−13.466	3.567	4.937
ATOM	2863	CG	PHE	283	−12.657	2.677	3.985
ATOM	2864	CD1	PHE	283	−12.443	1.326	4.287
ATOM	2865	CD2	PHE	283	−12.125	3.211	2.806
ATOM	2866	CE1	PHE	283	−11.648	0.535	3.453
ATOM	2867	CE2	PHE	283	−11.348	2.415	1.96
ATOM	2868	CZ	PHE	283	−11.088	1.083	2.296
ATOM	2869	HA	PHE	283	−14.805	4.462	3.494
ATOM	2870	H	PHE	283	−15.398	4.657	6.265
ATOM	2871	HB1	PHE	283	−12.951	4.531	5.074
ATOM	2872	HB2	PHE	283	−13.52	3.083	5.923
ATOM	2873	HD2	PHE	283	−12.314	4.247	2.544
ATOM	2874	HE2	PHE	283	−10.943	2.831	1.042
ATOM	2875	HZ	PHE	283	−10.452	0.474	1.661
ATOM	2876	HE1	PHE	283	−11.465	−0.505	3.706
ATOM	2877	HD1	PHE	283	−12.891	0.882	5.17
ATOM	2878	N	LEU	284	−15.731	1.56	4.903
ATOM	2879	CA	LEU	284	−16.166	0.213	4.537
ATOM	2880	C	LEU	284	−17.569	0.231	3.982
ATOM	2881	O	LEU	284	−17.791	−0.281	2.897
ATOM	2882	CB	LEU	284	−16.131	−0.743	5.767
ATOM	2883	CG	LEU	284	−16.772	−2.146	5.524
ATOM	2884	CD1	LEU	284	−16.076	−2.918	4.37
ATOM	2885	CD2	LEU	284	−16.715	−2.982	6.833
ATOM	2886	HA	LEU	284	−15.475	−0.172	3.769
ATOM	2887	H	LEU	284	−15.608	1.786	5.873
ATOM	2888	HB1	LEU	284	−15.084	−0.86	6.091
ATOM	2889	HB2	LEU	284	−16.685	−0.274	6.596
ATOM	2890	HG	LEU	284	−17.839	−2.026	5.266
ATOM	2891	HD21	LEU	284	−17.244	−2.459	7.644
ATOM	2892	HD22	LEU	284	−17.195	−3.964	6.693
ATOM	2893	HD23	LEU	284	−15.67	−3.144	7.134
ATOM	2894	HD11	LEU	284	−14.991	−2.975	4.545
ATOM	2895	HD12	LEU	284	−16.474	−3.942	4.299
ATOM	2896	HD13	LEU	284	−16.257	−2.427	3.404
ATOM	2897	N	ALA	285	−18.539	0.782	4.742
ATOM	2898	CA	ALA	285	−19.945	0.616	4.381
ATOM	2899	C	ALA	285	−20.47	1.682	3.445
ATOM	2900	O	ALA	285	−21.619	1.55	3.055
ATOM	2901	CB	ALA	285	−20.791	0.505	5.677
ATOM	2902	HA	ALA	285	−20.068	−0.337	3.842
ATOM	2903	H	ALA	285	−18.317	1.286	5.579
ATOM	2904	HB1	ALA	285	−21.808	0.156	5.451
ATOM	2905	HB2	ALA	285	−20.329	−0.218	6.367
ATOM	2906	HB3	ALA	285	−20.848	1.482	6.179
ATOM	2907	N	PHE	286	−19.687	2.717	3.052
ATOM	2908	CA	PHE	286	−20.159	3.664	2.036
ATOM	2909	C	PHE	286	−19.142	3.847	0.928
ATOM	2910	O	PHE	286	−19.489	3.612	−0.22
ATOM	2911	CB	PHE	286	−20.54	5.045	2.623
ATOM	2912	CG	PHE	286	−21.015	5.938	1.465
ATOM	2913	CD1	PHE	286	−22.359	5.94	1.077
ATOM	2914	CD2	PHE	286	−20.103	6.742	0.772
ATOM	2915	CE1	PHE	286	−22.796	6.775	0.043
ATOM	2916	CE2	PHE	286	−20.532	7.562	−0.275
ATOM	2917	CZ	PHE	286	−21.882	7.587	−0.634
ATOM	2918	HA	PHE	286	−21.078	3.295	1.553
ATOM	2919	H	PHE	286	−18.769	2.849	3.432
ATOM	2920	HB1	PHE	286	−21.338	4.926	3.373
ATOM	2921	HB2	PHE	286	−19.679	5.506	3.126
ATOM	2922	HD2	PHE	286	−19.052	6.728	1.041
ATOM	2923	HE2	PHE	286	−19.817	8.179	−0.81
ATOM	2924	HZ	PHE	286	−22.22	8.234	−1.438
ATOM	2925	HE1	PHE	286	−23.844	6.791	−0.237
ATOM	2926	HD1	PHE	286	−23.068	5.287	1.572
ATOM	2927	N	ALA	287	−17.892	4.281	1.204
ATOM	2928	CA	ALA	287	−16.974	4.552	0.099
ATOM	2929	C	ALA	287	−16.807	3.319	−0.757
ATOM	2930	O	ALA	287	−17.003	3.408	−1.958
ATOM	2931	CB	ALA	287	−15.578	5.039	0.565
ATOM	2932	HA	ALA	287	−17.414	5.357	−0.513
ATOM	2933	H	ALA	287	−17.587	4.467	2.14
ATOM	2934	HB1	ALA	287	−14.968	5.323	−0.307
ATOM	2935	HB2	ALA	287	−15.681	5.915	1.224
ATOM	2936	HB3	ALA	287	−15.049	4.243	1.106
ATOM	2937	N	LEU	288	−16.442	2.154	−0.178
ATOM	2938	CA	LEU	288	−16.23	0.981	−1.024
ATOM	2939	C	LEU	288	−17.459	0.635	−1.851
ATOM	2940	O	LEU	288	−17.316	0.632	−3.066
ATOM	2941	CB	LEU	288	−15.646	−0.248	−0.271
ATOM	2942	CG	LEU	288	−14.229	−0.037	0.356
ATOM	2943	CD1	LEU	288	−13.762	−1.365	1.018
ATOM	2944	CD2	LEU	288	−13.166	0.424	−0.683
ATOM	2945	HA	LEU	288	−15.472	1.271	−1.768
ATOM	2946	H	LEU	288	−16.299	2.087	0.814
ATOM	2947	HB1	LEU	288	−16.335	−0.531	0.536
ATOM	2948	HB2	LEU	288	−15.594	−1.087	−0.983
ATOM	2949	HG	LEU	288	−14.28	0.727	1.15
ATOM	2950	HD21	LEU	288	−13.32	1.473	−0.978
ATOM	2951	HD22	LEU	288	−12.153	0.359	−0.259
ATOM	2952	HD23	LEU	288	−13.204	−0.213	−1.579
ATOM	2953	HD11	LEU	288	−13.665	−2.158	0.262
ATOM	2954	HD12	LEU	288	−12.788	−1.238	1.512
ATOM	2955	HD13	LEU	288	−14.486	−1.693	1.778
ATOM	2956	N	PRO	289	−18.684	0.342	−1.341
ATOM	2957	CA	PRO	289	−19.775	0.046	−2.258
ATOM	2958	C	PRO	289	−20.067	1.222	−3.163
ATOM	2959	O	PRO	289	−20.403	0.988	−4.312
ATOM	2960	CB	PRO	289	−20.921	−0.285	−1.27
ATOM	2961	CG	PRO	289	−20.52	0.409	0.051
ATOM	2962	CD	PRO	289	−18.978	0.286	0.085
ATOM	2963	HA	PRO	289	−19.534	−0.836	−2.876
ATOM	2964	HD2	PRO	289	−18.703	−0.704	0.48
ATOM	2965	HD1	PRO	289	−18.531	1.083	0.694
ATOM	2966	HG2	PRO	289	−21.008	−0.033	0.936
ATOM	2967	HG1	PRO	289	−20.819	1.464	−0.018
ATOM	2968	HB1	PRO	289	−21.904	0.045	−1.64
ATOM	2969	HB2	PRO	289	−20.951	−1.373	−1.09
ATOM	2970	N	PHE	290	−19.938	2.49	−2.711
ATOM	2971	CA	PHE	290	−20.169	3.607	−3.629
ATOM	2972	C	PHE	290	−19.21	3.515	−4.796
ATOM	2973	O	PHE	290	−19.617	3.696	−5.934
ATOM	2974	CB	PHE	290	−20.002	4.981	−2.927
ATOM	2975	CG	PHE	290	−20.306	6.104	−3.927
ATOM	2976	CD1	PHE	290	−21.6	6.629	−4.028
ATOM	2977	CD2	PHE	290	−19.293	6.608	−4.75
ATOM	2978	CE1	PHE	290	−21.886	7.627	−4.963
ATOM	2979	CE2	PHE	290	−19.578	7.606	−5.687
ATOM	2980	CZ	PHE	290	−20.876	8.111	−5.799
ATOM	2981	HA	PHE	290	−21.201	3.552	−4.011
ATOM	2982	H	PHE	290	−19.642	2.686	−1.773
ATOM	2983	HB1	PHE	290	−20.69	5.047	−2.069
ATOM	2984	HB2	PHE	290	−18.977	5.092	−2.544
ATOM	2985	HD2	PHE	290	−18.281	6.224	−4.669
ATOM	2986	HE2	PHE	290	−18.79	7.985	−6.331
ATOM	2987	HZ	PHE	290	−21.099	8.878	−6.534
ATOM	2988	HE1	PHE	290	−22.893	8.027	−5.042
ATOM	2989	HD1	PHE	290	−22.389	6.261	−3.38
ATOM	2990	N	VAL	291	−17.916	3.23	−4.527
ATOM	2991	CA	VAL	291	−16.95	3.117	−5.617
ATOM	2992	C	VAL	291	−17.307	1.934	−6.486
ATOM	2993	O	VAL	291	−17.27	2.077	−7.698
ATOM	2994	CB	VAL	291	−15.484	2.992	−5.101
ATOM	2995	CG1	VAL	291	−14.507	2.585	−6.242
ATOM	2996	CG2	VAL	291	−15.013	4.334	−4.472
ATOM	2997	HA	VAL	291	−17.012	4.026	−6.237
ATOM	2998	H	VAL	291	−17.613	3.062	−3.586
ATOM	2999	HB	VAL	291	−15.446	2.202	−4.332
ATOM	3000	HG11	VAL	291	−14.573	3.3	−7.076
ATOM	3001	HG12	VAL	291	−13.47	2.573	−5.871
ATOM	3002	HG13	VAL	291	−14.735	1.578	−6.624
ATOM	3003	HG21	VAL	291	−15.708	4.683	−3.696
ATOM	3004	HG22	VAL	291	−14.02	4.213	−4.012
ATOM	3005	HG23	VAL	291	−14.945	5.116	−5.244
ATOM	3006	N	VAL	292	−17.647	0.753	−5.922
ATOM	3007	CA	VAL	292	−17.964	−0.384	−6.79
ATOM	3008	C	VAL	292	−19.182	−0.042	−7.619
ATOM	3009	O	VAL	292	−19.177	−0.295	−8.814
ATOM	3010	CB	VAL	292	−18.201	−1.721	−6.025
ATOM	3011	CG1	VAL	292	−18.628	−2.852	−7.006
ATOM	3012	CG2	VAL	292	−16.922	−2.166	−5.261
ATOM	3013	HA	VAL	292	−17.114	−0.54	−7.476
ATOM	3014	H	VAL	292	−17.707	0.66	−4.924
ATOM	3015	HB	VAL	292	−19.015	−1.566	−5.296
ATOM	3016	HG11	VAL	292	−17.865	−2.987	−7.789
ATOM	3017	HG12	VAL	292	−18.743	−3.807	−6.47
ATOM	3018	HG13	VAL	292	−19.587	−2.623	−7.494
ATOM	3019	HG21	VAL	292	−16.588	−1.407	−4.54
ATOM	3020	HG22	VAL	292	−17.117	−3.095	−4.702
ATOM	3021	HG23	VAL	292	−16.099	−2.353	−5.969
ATOM	3022	N	ILE	293	−20.239	0.536	−7.008
ATOM	3023	CA	ILE	293	−21.428	0.906	−7.779
ATOM	3024	C	ILE	293	−21.011	1.851	−8.884
ATOM	3025	O	ILE	293	−21.452	1.693	−10.012
ATOM	3026	CB	ILE	293	−22.513	1.578	−6.878
ATOM	3027	CG1	ILE	293	−23.107	0.553	−5.863
ATOM	3028	CG2	ILE	293	−23.649	2.214	−7.733
ATOM	3029	CD1	ILE	293	−23.686	1.222	−4.587
ATOM	3030	HA	ILE	293	−21.859	−0.002	−8.232
ATOM	3031	H	ILE	293	−20.197	0.751	−6.03
ATOM	3032	HB	ILE	293	−22.018	2.393	−6.323
ATOM	3033	HG11	ILE	293	−23.896	−0.036	−6.356
ATOM	3034	HG12	ILE	293	−22.331	−0.154	−5.531
ATOM	3035	HD11	ILE	293	−24.559	1.85	−4.816
ATOM	3036	HD12	ILE	293	−23.987	0.446	−3.869
ATOM	3037	HD13	ILE	293	−22.929	1.845	−4.092
ATOM	3038	HG21	ILE	293	−24.088	1.46	−8.403
ATOM	3039	HG22	ILE	293	−24.448	2.614	−7.093
ATOM	3040	HG23	ILE	293	−23.268	3.046	−8.346
ATOM	3041	N	THR	294	−20.158	2.853	−8.577
ATOM	3042	CA	THR	294	−19.786	3.827	−9.601
ATOM	3043	C	THR	294	−18.961	3.155	−10.676
ATOM	3044	O	THR	294	−19.277	3.29	−11.848
ATOM	3045	CB	THR	294	−19.018	5.04	−9
ATOM	3046	OG1	THR	294	−19.843	5.762	−8.065
ATOM	3047	CG2	THR	294	−18.603	6.045	−10.106
ATOM	3048	HA	THR	294	−20.71	4.226	−10.051
ATOM	3049	H	THR	294	−19.773	2.936	−7.654
ATOM	3050	HB	THR	294	−18.102	4.69	−8.492
ATOM	3051	HG1	THR	294	−20.095	5.254	−7.299
ATOM	3052	HG23	THR	294	−17.901	5.587	−10.821
ATOM	3053	HG21	THR	294	−19.491	6.395	−10.654
ATOM	3054	HG22	THR	294	−18.11	6.916	−9.647
ATOM	3055	N	ALA	295	−17.889	2.421	−10.313
ATOM	3056	CA	ALA	295	−17.066	1.774	−11.334
ATOM	3057	C	ALA	295	−17.917	0.835	−12.159
ATOM	3058	O	ALA	295	−17.821	0.837	−13.376
ATOM	3059	CB	ALA	295	−15.902	0.975	−10.693
ATOM	3060	HA	ALA	295	−16.642	2.553	−11.99
ATOM	3061	H	ALA	295	−17.652	2.304	−9.347
ATOM	3062	HB1	ALA	295	−15.291	0.499	−11.476
ATOM	3063	HB2	ALA	295	−15.26	1.649	−10.105
ATOM	3064	HB3	ALA	295	−16.294	0.192	−10.025
ATOM	3065	N	ALA	296	−18.773	0.022	−11.504
ATOM	3066	CA	ALA	296	−19.664	−0.853	−12.26
ATOM	3067	C	ALA	296	−20.524	−0.018	−13.18
ATOM	3068	O	ALA	296	−20.684	−0.4	−14.329
ATOM	3069	CB	ALA	296	−20.56	−1.684	−11.311
ATOM	3070	HA	ALA	296	−19.055	−1.546	−12.866
ATOM	3071	H	ALA	296	−18.832	0.034	−10.502
ATOM	3072	HB1	ALA	296	−21.285	−2.284	−11.883
ATOM	3073	HB2	ALA	296	−19.945	−2.359	−10.695
ATOM	3074	HB3	ALA	296	−21.098	−0.997	−10.644
ATOM	3075	N	TYR	297	−21.078	1.13	−12.722
ATOM	3076	CA	TYR	297	−21.82	1.975	−13.653
ATOM	3077	C	TYR	297	−20.929	2.351	−14.816
ATOM	3078	O	TYR	297	−21.373	2.258	−15.949
ATOM	3079	CB	TYR	297	−22.415	3.283	−13.067
ATOM	3080	CG	TYR	297	−22.918	4.142	−14.241
ATOM	3081	CD1	TYR	297	−24.025	3.732	−14.994
ATOM	3082	CD2	TYR	297	−22.257	5.325	−14.593
ATOM	3083	CE1	TYR	297	−24.4	4.432	−16.146
ATOM	3084	CE2	TYR	297	−22.664	6.052	−15.715
ATOM	3085	CZ	TYR	297	−23.719	5.6	−16.511
ATOM	3086	OH	TYR	297	−24.07	6.323	−17.655
ATOM	3087	HA	TYR	297	−22.669	1.388	−14.024
ATOM	3088	H	TYR	297	−20.966	1.433	−11.771
ATOM	3089	HB2	TYR	297	−23.242	3.057	−12.374
ATOM	3090	HB1	TYR	297	−21.642	3.821	−12.502
ATOM	3091	HD2	TYR	297	−21.419	5.684	−14.004
ATOM	3092	HE2	TYR	297	−22.158	6.976	−15.973
ATOM	3093	HE1	TYR	297	−25.22	4.063	−16.754
ATOM	3094	HD1	TYR	297	−24.594	2.86	−14.692
ATOM	3095	HH	TYR	297	−24.903	6.069	−18.04
ATOM	3096	N	VAL	298	−19.675	2.786	−14.571
ATOM	3097	CA	VAL	298	−18.817	3.176	−15.691
ATOM	3098	C	VAL	298	−18.662	2.009	−16.644
ATOM	3099	O	VAL	298	−18.623	2.232	−17.843
ATOM	3100	CB	VAL	298	−17.435	3.726	−15.228
ATOM	3101	CG1	VAL	298	−16.477	3.945	−16.434
ATOM	3102	CG2	VAL	298	−17.601	5.067	−14.455
ATOM	3103	HA	VAL	298	−19.327	3.983	−16.243
ATOM	3104	H	VAL	298	−19.326	2.826	−13.632
ATOM	3105	HB	VAL	298	−16.968	2.984	−14.559
ATOM	3106	HG11	VAL	298	−16.939	4.619	−17.172
ATOM	3107	HG12	VAL	298	−15.529	4.392	−16.096
ATOM	3108	HG13	VAL	298	−16.237	2.991	−16.93
ATOM	3109	HG21	VAL	298	−18.268	4.962	−13.589
ATOM	3110	HG22	VAL	298	−16.624	5.419	−14.086
ATOM	3111	HG23	VAL	298	−18.019	5.841	−15.118
ATOM	3112	N	ARG	299	−18.579	0.747	−16.17
ATOM	3113	CA	ARG	299	−18.527	−0.363	−17.123
ATOM	3114	C	ARG	299	−19.861	−0.479	−17.835
ATOM	3115	O	ARG	299	−19.889	−0.597	−19.049
ATOM	3116	CB	ARG	299	−18.197	−1.724	−16.451
ATOM	3117	CG	ARG	299	−16.806	−1.733	−15.758
ATOM	3118	CD	ARG	299	−16.452	−3.154	−15.238
ATOM	3119	NE	ARG	299	−15.201	−3.188	−14.477
ATOM	3120	CZ	ARG	299	−14.696	−4.289	−13.961
ATOM	3121	NH1	ARG	299	−15.274	−5.461	−14.081
ATOM	3122	NH2	ARG	299	−13.567	−4.217	−13.297
ATOM	3123	HA	ARG	299	−17.744	−0.161	−17.874
ATOM	3124	H	ARG	299	−18.61	0.565	−15.184
ATOM	3125	HB1	ARG	299	−18.976	−1.96	−15.71
ATOM	3126	HB2	ARG	299	−18.213	−2.503	−17.231
ATOM	3127	HG1	ARG	299	−16.03	−1.407	−16.471
ATOM	3128	HG2	ARG	299	−16.807	−1.034	−14.908
ATOM	3129	HD1	ARG	299	−17.284	−3.503	−14.603
ATOM	3130	HD2	ARG	299	−16.349	−3.808	−16.119
ATOM	3131	HE	ARG	299	−14.701	−2.294	−14.351
ATOM	3132	HH12	ARG	299	−14.853	−6.306	−13.667
ATOM	3133	HH11	ARG	299	−16.159	−5.581	−14.589
ATOM	3134	HH22	ARG	299	−13.138	−5.055	−12.878
ATOM	3135	HH21	ARG	299	−13.074	−3.32	−13.175
ATOM	3136	N	ILE	300	−20.993	−0.446	−17.101
ATOM	3137	CA	ILE	300	−22.31	−0.54	−17.748
ATOM	3138	C	ILE	300	−22.476	0.547	−18.789
ATOM	3139	O	ILE	300	−23.066	0.285	−19.828
ATOM	3140	CB	ILE	300	−23.429	−0.486	−16.666
ATOM	3141	CG1	ILE	300	−23.42	−1.806	−15.832
ATOM	3142	CG2	ILE	300	−24.831	−0.197	−17.269
ATOM	3143	CD1	ILE	300	−24.034	−1.643	−14.418
ATOM	3144	HA	ILE	300	−22.393	−1.502	−18.275
ATOM	3145	H	ILE	300	−20.931	−0.317	−16.108
ATOM	3146	HB	ILE	300	−23.206	0.372	−16.02
ATOM	3147	HG11	ILE	300	−23.965	−2.589	−16.384
ATOM	3148	HG12	ILE	300	−22.389	−2.168	−15.686
ATOM	3149	HD11	ILE	300	−25.091	−1.345	−14.469
ATOM	3150	HD12	ILE	300	−23.96	−2.597	−13.875
ATOM	3151	HD13	ILE	300	−23.484	−0.89	−13.837
ATOM	3152	HG21	ILE	300	−25.114	−0.991	−17.976
ATOM	3153	HG22	ILE	300	−25.587	−0.145	−16.472
ATOM	3154	HG23	ILE	300	−24.846	0.771	−17.795
ATOM	3155	N	LEU	301	−21.95	1.765	−18.519
ATOM	3156	CA	LEU	301	−22.023	2.862	−19.489
ATOM	3157	C	LEU	301	−21.674	2.312	−20.857
ATOM	3158	O	LEU	301	−22.399	2.593	−21.797
ATOM	3159	CB	LEU	301	−21.068	4.018	−19.049
ATOM	3160	CG	LEU	301	−21.218	5.403	−19.747
ATOM	3161	CD1	LEU	301	−20.335	6.453	−19.011
ATOM	3162	CD2	LEU	301	−20.812	5.387	−21.247
ATOM	3163	HA	LEU	301	−23.06	3.232	−19.487
ATOM	3164	H	LEU	301	−21.509	1.924	−17.634
ATOM	3165	HB1	LEU	301	−21.257	4.199	−17.979
ATOM	3166	HB2	LEU	301	−20.027	3.688	−19.165
ATOM	3167	HG	LEU	301	−22.266	5.73	−19.655
ATOM	3168	HD21	LEU	301	−21.512	4.795	−21.844
ATOM	3169	HD22	LEU	301	−20.82	6.407	−21.661
ATOM	3170	HD23	LEU	301	−19.802	4.969	−21.37
ATOM	3171	HD11	LEU	301	−19.272	6.176	−19.081
ATOM	3172	HD12	LEU	301	−20.466	7.453	−19.455
ATOM	3173	HD13	LEU	301	−20.605	6.522	−17.946
ATOM	3174	N	GLN	302	−20.591	1.5	−20.965
ATOM	3175	CA	GLN	302	−20.178	0.924	−22.252
ATOM	3176	C	GLN	302	−21.353	0.655	−23.171
ATOM	3177	O	GLN	302	−21.285	1.015	−24.335
ATOM	3178	CB	GLN	302	−19.436	−0.439	−22.087
ATOM	3179	CG	GLN	302	−18.001	−0.315	−21.499
ATOM	3180	CD	GLN	302	−17.453	−1.67	−21.108
ATOM	3181	OE1	GLN	302	−17.229	−1.907	−19.931
ATOM	3182	NE2	GLN	302	−17.22	−2.595	−22.064
ATOM	3183	HA	GLN	302	−19.506	1.642	−22.749
ATOM	3184	H	GLN	302	−20.049	1.291	−20.149
ATOM	3185	HB1	GLN	302	−20.047	−1.101	−21.455
ATOM	3186	HB2	GLN	302	−19.35	−0.92	−23.075
ATOM	3187	HG1	GLN	302	−17.33	0.142	−22.243
ATOM	3188	HG2	GLN	302	−17.987	0.33	−20.609
ATOM	3189	HE22	GLN	302	−16.865	−3.493	−21.799
ATOM	3190	HE21	GLN	302	−17.387	−2.408	−23.031
ATOM	3191	N	ARG	303	−22.428	0.012	−22.659
ATOM	3192	CA	ARG	303	−23.606	−0.273	−23.483
ATOM	3193	C	ARG	303	−24.819	0.562	−23.122
ATOM	3194	O	ARG	303	−25.538	0.943	−24.034
ATOM	3195	CB	ARG	303	−24.004	−1.765	−23.315
ATOM	3196	CG	ARG	303	−23.053	−2.714	−24.094
ATOM	3197	CD	ARG	303	−23.43	−4.205	−23.858
ATOM	3198	NE	ARG	303	−22.83	−5.102	−24.851
ATOM	3199	CZ	ARG	303	−23.106	−6.386	−24.93
ATOM	3200	NH1	ARG	303	−23.879	−7.002	−24.067
ATOM	3201	NH2	ARG	303	−22.59	−7.084	−25.915
ATOM	3202	HA	ARG	303	−23.407	−0.094	−24.553
ATOM	3203	H	ARG	303	−22.427	−0.261	−21.694
ATOM	3204	HB1	ARG	303	−24.007	−2.021	−22.246
ATOM	3205	HB2	ARG	303	−25.026	−1.914	−23.704
ATOM	3206	HG1	ARG	303	−23.146	−2.483	−25.168
ATOM	3207	HG2	ARG	303	−22.006	−2.541	−23.793
ATOM	3208	HD1	ARG	303	−23.112	−4.476	−22.84
ATOM	3209	HD2	ARG	303	−24.526	−4.292	−23.936
ATOM	3210	HE	ARG	303	−22.19	−4.681	−25.544
ATOM	3211	HH12	ARG	303	−24.086	−8.007	−24.161
ATOM	3212	HH11	ARG	303	−24.279	−6.516	−23.252
ATOM	3213	HH22	ARG	303	−22.794	−8.089	−26.022
ATOM	3214	HH21	ARG	303	−21.973	−6.647	−26.616
ATOM	3215	N	MET	304	−25.107	0.834	−21.829
ATOM	3216	CA	MET	304	−26.367	1.483	−21.469
ATOM	3217	C	MET	304	−26.061	2.842	−20.893
ATOM	3218	O	MET	304	−26.211	3.032	−19.697
ATOM	3219	CB	MET	304	−27.138	0.542	−20.505
ATOM	3220	CG	MET	304	−27.379	−0.836	−21.177
ATOM	3221	SD	MET	304	−28.293	−1.912	−20.03
ATOM	3222	CE	MET	304	−28.665	−3.338	−21.1
ATOM	3223	HA	MET	304	−27.029	1.655	−22.334
ATOM	3224	H	MET	304	−24.493	0.578	−21.078
ATOM	3225	HB1	MET	304	−26.558	0.395	−19.583
ATOM	3226	HB2	MET	304	−28.104	1	−20.233
ATOM	3227	HG1	MET	304	−27.96	−0.704	−22.102
ATOM	3228	HG2	MET	304	−26.43	−1.332	−21.425
ATOM	3229	LPD1	MET	304	−27.91	−2.093	−19.499
ATOM	3230	LPD2	MET	304	−28.861	−1.613	−19.808
ATOM	3231	HE1	MET	304	−27.785	−3.989	−21.186
ATOM	3232	HE2	MET	304	−29.486	−3.913	−20.654
ATOM	3233	HE3	MET	304	−28.964	−3.005	−22.104
ATOM	3234	N	THR	305	−25.622	3.794	−21.75
ATOM	3235	CA	THR	305	−25.248	5.119	−21.261
ATOM	3236	C	THR	305	−26.333	5.76	−20.416
ATOM	3237	O	THR	305	−26.213	5.709	−19.202
ATOM	3238	CB	THR	305	−24.747	6.028	−22.423
ATOM	3239	OG1	THR	305	−23.668	5.336	−23.075
ATOM	3240	CG2	THR	305	−24.276	7.416	−21.911
ATOM	3241	HA	THR	305	−24.373	4.975	−20.61
ATOM	3242	H	THR	305	−25.476	3.584	−22.72
ATOM	3243	HB	THR	305	−25.548	6.164	−23.168
ATOM	3244	HG1	THR	305	−23.301	5.808	−23.816
ATOM	3245	HG23	THR	305	−25.097	7.951	−21.412
ATOM	3246	HG21	THR	305	−23.447	7.3	−21.198
ATOM	3247	HG22	THR	305	−23.924	8.03	−22.754
ATOM	3248	N	SER	306	−27.389	6.38	−20.996
ATOM	3249	CA	SER	306	−28.354	7.12	−20.176
ATOM	3250	C	SER	306	−29.596	7.406	−20.998
ATOM	3251	O	SER	306	−29.965	8.56	−21.149
ATOM	3252	CB	SER	306	−27.723	8.457	−19.689
ATOM	3253	OG	SER	306	−26.567	8.222	−18.865
ATOM	3254	HA	SER	306	−28.655	6.523	−19.3
ATOM	3255	H	SER	306	−27.509	6.392	−21.988
ATOM	3256	HB1	SER	306	−27.433	9.054	−20.569
ATOM	3257	HB2	SER	306	−28.468	9.023	−19.105
ATOM	3258	HG	SER	306	−26.15	9.021	−18.557
ATOM	3259	N	SER	307	−30.255	6.374	−21.572
ATOM	3260	CA	SER	307	−31.311	6.647	−22.548
ATOM	3261	C	SER	307	−32.22	5.45	−22.735
ATOM	3262	O	SER	307	−31.899	4.606	−23.557
ATOM	3263	CB	SER	307	−30.594	7.004	−23.878
ATOM	3264	OG	SER	307	−29.645	5.972	−24.215
ATOM	3265	HA	SER	307	−31.932	7.505	−22.241
ATOM	3266	H	SER	307	−29.959	5.426	−21.436
ATOM	3267	HB1	SER	307	−31.343	7.122	−24.68
ATOM	3268	HB2	SER	307	−30.059	7.962	−23.756
ATOM	3269	HG	SER	307	−29.174	6.157	−25.023
ATOM	3270	N	VAL	308	−33.357	5.349	−21.999
ATOM	3271	CA	VAL	308	−34.25	4.2	−22.162
ATOM	3272	C	VAL	308	−35.69	4.675	−22.233
ATOM	3273	O	VAL	308	−36.389	4.585	−21.235
ATOM	3274	CB	VAL	308	−34.027	3.152	−21.025
ATOM	3275	CG1	VAL	308	−34.529	1.751	−21.478
ATOM	3276	CG2	VAL	308	−32.549	3.132	−20.541
ATOM	3277	HA	VAL	308	−34.053	3.696	−23.122
ATOM	3278	H	VAL	308	−33.6	6.033	−21.308
ATOM	3279	HB	VAL	308	−34.614	3.42	−20.133
ATOM	3280	HG11	VAL	308	−33.989	1.404	−22.371
ATOM	3281	HG12	VAL	308	−34.391	1.01	−20.677
ATOM	3282	HG13	VAL	308	−35.602	1.797	−21.724
ATOM	3283	HG21	VAL	308	−32.296	4.066	−20.017
ATOM	3284	HG22	VAL	308	−32.376	2.297	−19.848
ATOM	3285	HG23	VAL	308	−31.857	3.026	−21.38
ATOM	3286	N	ALA	309	−36.15	5.186	−23.403
ATOM	3287	CA	ALA	309	−37.571	5.511	−23.572
ATOM	3288	C	ALA	309	−38.352	4.335	−24.145
ATOM	3289	O	ALA	309	−39.34	4.002	−23.507
ATOM	3290	CB	ALA	309	−37.806	6.857	−24.314
ATOM	3291	HA	ALA	309	−38.008	5.707	−22.576
ATOM	3292	H	ALA	309	−35.536	5.313	−24.181
ATOM	3293	HB1	ALA	309	−38.887	7.065	−24.377
ATOM	3294	HB2	ALA	309	−37.326	7.673	−23.751
ATOM	3295	HB3	ALA	309	−37.399	6.876	−25.331
ATOM	3296	N	PRO	310	−38.046	3.637	−25.275
ATOM	3297	CA	PRO	310	−38.853	2.473	−25.634
ATOM	3298	C	PRO	310	−38.653	1.347	−24.644
ATOM	3299	O	PRO	310	−37.848	1.498	−23.738
ATOM	3300	CB	PRO	310	−38.271	2.11	−27.024
ATOM	3301	CG	PRO	310	−37.534	3.393	−27.47
ATOM	3302	CD	PRO	310	−36.929	3.942	−26.156
ATOM	3303	HA	PRO	310	−39.916	2.756	−25.711
ATOM	3304	HD2	PRO	310	−36.664	4.996	−26.288
ATOM	3305	HD1	PRO	310	−36.043	3.361	−25.852
ATOM	3306	HG2	PRO	310	−38.277	4.112	−27.856
ATOM	3307	HG1	PRO	310	−36.777	3.21	−28.25
ATOM	3308	HB1	PRO	310	−37.521	1.312	−26.928
ATOM	3309	HB2	PRO	310	−39.039	1.78	−27.743
ATOM	3310	N	ALA	311	−39.36	0.203	−24.786
ATOM	3311	CA	ALA	311	−39.231	−0.845	−23.775
ATOM	3312	C	ALA	311	−39.84	−2.168	−24.188
ATOM	3313	O	ALA	311	−40.556	−2.201	−25.174
ATOM	3314	CB	ALA	311	−39.985	−0.372	−22.509
ATOM	3315	HA	ALA	311	−38.167	−1.015	−23.544
ATOM	3316	HB1	ALA	311	−39.955	−1.163	−21.751
ATOM	3317	HB2	ALA	311	−39.534	0.538	−22.086
ATOM	3318	HB3	ALA	311	−41.038	−0.163	−22.756
ATOM	3319	H	ALA	311	−40.013	0.069	−25.535
ATOM	3320	N	SER	312	−39.577	−3.256	−23.421
ATOM	3321	CA	SER	312	−40.21	−4.547	−23.696
ATOM	3322	C	SER	312	−40.432	−5.266	−22.374
ATOM	3323	O	SER	312	−39.445	−5.627	−21.752
ATOM	3324	CB	SER	312	−39.281	−5.373	−24.618
ATOM	3325	OG	SER	312	−39.078	−4.678	−25.86
ATOM	3326	HA	SER	312	−41.172	−4.413	−24.219
ATOM	3327	HB1	SER	312	−38.313	−5.527	−24.121
ATOM	3328	HB2	SER	312	−39.744	−6.353	−24.804
ATOM	3329	HG	SER	312	−38.525	−5.151	−26.474
ATOM	3330	H	SER	312	−38.931	−3.211	−22.656
ATOM	3331	N	GLN	313	−41.684	−5.477	−21.897
ATOM	3332	CA	GLN	313	−41.876	−6.097	−20.58
ATOM	3333	C	GLN	313	−41.413	−7.546	−20.561
ATOM	3334	O	GLN	313	−42.215	−8.443	−20.754
ATOM	3335	CB	GLN	313	−43.321	−5.946	−20.011
ATOM	3336	CG	GLN	313	−44.476	−6.428	−20.937
ATOM	3337	CD	GLN	313	−45.695	−6.716	−20.092
ATOM	3338	OE1	GLN	313	−46.601	−5.899	−20.048
ATOM	3339	NE2	GLN	313	−45.743	−7.869	−19.391
ATOM	3340	HA	GLN	313	−41.244	−5.546	−19.861
ATOM	3341	HB1	GLN	313	−43.347	−6.516	−19.069
ATOM	3342	HB2	GLN	313	−43.517	−4.889	−19.76
ATOM	3343	HG1	GLN	313	−44.726	−5.655	−21.681
ATOM	3344	HG2	GLN	313	−44.214	−7.341	−21.49
ATOM	3345	HE22	GLN	313	−46.545	−8.065	−18.826
ATOM	3346	HE21	GLN	313	−44.998	−8.536	−19.433
ATOM	3347	H	GLN	313	−42.488	−5.196	−22.422
ATOM	3348	N	ARG	314	−40.108	−7.808	−20.317
ATOM	3349	CA	ARG	314	−39.604	−9.187	−20.278
ATOM	3350	C	ARG	314	−39.717	−9.938	−21.589
ATOM	3351	O	ARG	314	−39.477	−11.135	−21.578
ATOM	3352	CB	ARG	314	−40.136	−9.993	−19.057
ATOM	3353	CG	ARG	314	−39.696	−9.325	−17.723
ATOM	3354	CD	ARG	314	−40.109	−10.157	−16.474
ATOM	3355	NE	ARG	314	−39.675	−9.487	−15.244
ATOM	3356	CZ	ARG	314	−40.067	−9.824	−14.036
ATOM	3357	NH1	ARG	314	−40.861	−10.84	−13.802
ATOM	3358	NH2	ARG	314	−39.641	−9.117	−13.018
ATOM	3359	HA	ARG	314	−38.519	−9.164	−20.124
ATOM	3360	H	ARG	314	−39.468	−7.054	−20.157
ATOM	3361	HB1	ARG	314	−41.234	−10.068	−19.101
ATOM	3362	HB2	ARG	314	−39.726	−11.017	−19.076
ATOM	3363	HG1	ARG	314	−38.598	−9.212	−17.715
ATOM	3364	HG2	ARG	314	−40.148	−8.32	−17.657
ATOM	3365	HD1	ARG	314	−41.204	−10.276	−16.523
ATOM	3366	HD2	ARG	314	−39.628	−11.147	−16.522
ATOM	3367	HE	ARG	314	−39.008	−8.701	−15.347
ATOM	3368	HH12	ARG	314	−41.15	−11.066	−12.84
ATOM	3369	HH11	ARG	314	−41.203	−11.445	−14.556
ATOM	3370	HH22	ARG	314	−39.894	−9.368	−12.051
ATOM	3371	HH21	ARG	314	−39.01	−8.313	−13.14
ATOM	3372	N	SER	315	−40.038	−9.302	−22.739
ATOM	3373	CA	SER	315	−40.243	−10.083	−23.961
ATOM	3374	C	SER	315	−38.95	−10.448	−24.668
ATOM	3375	O	SER	315	−38.767	−11.629	−24.921
ATOM	3376	CB	SER	315	−41.207	−9.354	−24.935
ATOM	3377	OG	SER	315	−42.377	−8.946	−24.201
ATOM	3378	HA	SER	315	−40.772	−11.014	−23.691
ATOM	3379	H	SER	315	−40.168	−8.31	−22.778
ATOM	3380	HB1	SER	315	−40.716	−8.467	−25.363
ATOM	3381	HB2	SER	315	−41.485	−10.032	−25.762
ATOM	3382	HG	SER	315	−43.022	−8.505	−24.746
ATOM	3383	N	ILE	316	−38.054	−9.49	−25.028
ATOM	3384	CA	ILE	316	−36.915	−9.821	−25.901
ATOM	3385	C	ILE	316	−35.593	−9.22	−25.446
ATOM	3386	O	ILE	316	−34.682	−9.987	−25.172
ATOM	3387	CB	ILE	316	−37.21	−9.415	−27.382
ATOM	3388	CG1	ILE	316	−38.597	−9.962	−27.84
ATOM	3389	CG2	ILE	316	−36.076	−9.913	−28.326
ATOM	3390	CD1	ILE	316	−38.965	−9.606	−29.306
ATOM	3391	HA	ILE	316	−36.758	−10.912	−25.922
ATOM	3392	H	ILE	316	−38.202	−8.532	−24.78
ATOM	3393	HB	ILE	316	−37.252	−8.315	−27.442
ATOM	3394	HG11	ILE	316	−38.631	−11.058	−27.717
ATOM	3395	HG12	ILE	316	−39.378	−9.521	−27.203
ATOM	3396	HD11	ILE	316	−38.337	−10.155	−30.024
ATOM	3397	HD12	ILE	316	−40.014	−9.88	−29.505
ATOM	3398	HD13	ILE	316	−38.85	−8.524	−29.481
ATOM	3399	HG21	ILE	316	−36.105	−11.009	−28.413
ATOM	3400	HG22	ILE	316	−36.177	−9.476	−29.33
ATOM	3401	HG23	ILE	316	−35.084	−9.626	−27.951
ATOM	3402	N	ARG	317	−35.425	−7.875	−25.382
ATOM	3403	CA	ARG	317	−34.08	−7.299	−25.233
ATOM	3404	C	ARG	317	−34.045	−6.084	−24.328
ATOM	3405	O	ARG	317	−33.327	−6.11	−23.34
ATOM	3406	CB	ARG	317	−33.566	−6.938	−26.655
ATOM	3407	CG	ARG	317	−32.153	−6.288	−26.654
ATOM	3408	CD	ARG	317	−31.696	−5.943	−28.1
ATOM	3409	NE	ARG	317	−30.355	−5.351	−28.14
ATOM	3410	CZ	ARG	317	−29.758	−4.971	−29.25
ATOM	3411	NH1	ARG	317	−30.315	−5.087	−30.432
ATOM	3412	NH2	ARG	317	−28.554	−4.453	−29.178
ATOM	3413	HA	ARG	317	−33.375	−8.028	−24.797
ATOM	3414	H	ARG	317	−36.191	−7.257	−25.554
ATOM	3415	HB1	ARG	317	−33.527	−7.862	−27.252
ATOM	3416	HB2	ARG	317	−34.281	−6.255	−27.14
ATOM	3417	HG1	ARG	317	−32.16	−5.362	−26.055
ATOM	3418	HG2	ARG	317	−31.432	−6.987	−26.198
ATOM	3419	HD1	ARG	317	−31.703	−6.876	−28.69
ATOM	3420	HD2	ARG	317	−32.427	−5.233	−28.522
ATOM	3421	HE	ARG	317	−29.864	−5.235	−27.239
ATOM	3422	HH12	ARG	317	−29.822	−4.78	−31.284
ATOM	3423	HH11	ARG	317	−31.254	−5.485	−30.552
ATOM	3424	HH22	ARG	317	−28.054	−4.144	−30.025
ATOM	3425	HH21	ARG	317	−28.072	−4.341	−28.274
ATOM	3426	N	LEU	318	−34.793	−4.995	−24.623
ATOM	3427	CA	LEU	318	−34.72	−3.821	−23.751
ATOM	3428	C	LEU	318	−35.107	−4.213	−22.342
ATOM	3429	O	LEU	318	−34.692	−3.527	−21.424
ATOM	3430	CB	LEU	318	−35.582	−2.619	−24.227
ATOM	3431	CG	LEU	318	−34.908	−1.777	−25.353
ATOM	3432	CD1	LEU	318	−34.621	−2.599	−26.641
ATOM	3433	CD2	LEU	318	−35.802	−0.556	−25.697
ATOM	3434	HA	LEU	318	−33.668	−3.494	−23.705
ATOM	3435	H	LEU	318	−35.415	−4.98	−25.405
ATOM	3436	HB1	LEU	318	−36.575	−2.979	−24.54
ATOM	3437	HB2	LEU	318	−35.727	−1.943	−23.367
ATOM	3438	HG	LEU	318	−33.945	−1.387	−24.979
ATOM	3439	HD21	LEU	318	−35.943	0.08	−24.81
ATOM	3440	HD22	LEU	318	−35.335	0.058	−26.483
ATOM	3441	HD23	LEU	318	−36.786	−0.899	−26.049
ATOM	3442	HD11	LEU	318	−35.549	−3.054	−27.021
ATOM	3443	HD12	LEU	318	−34.209	−1.948	−27.427
ATOM	3444	HD13	LEU	318	−33.88	−3.389	−26.449
ATOM	3445	N	ARG	319	−35.868	−5.309	−22.137
ATOM	3446	CA	ARG	319	−36.099	−5.824	−20.789
ATOM	3447	C	ARG	319	−34.894	−5.694	−19.882
ATOM	3448	O	ARG	319	−35.047	−5.272	−18.745
ATOM	3449	CB	ARG	319	−36.546	−7.314	−20.853
ATOM	3450	CG	ARG	319	−35.583	−8.306	−21.575
ATOM	3451	CD	ARG	319	−36.277	−9.675	−21.843
ATOM	3452	NE	ARG	319	−35.543	−10.55	−22.756
ATOM	3453	CZ	ARG	319	−36.028	−11.685	−23.218
ATOM	3454	NH1	ARG	319	−37.186	−12.176	−22.843
ATOM	3455	NH2	ARG	319	−35.326	−12.354	−24.102
ATOM	3456	HA	ARG	319	−36.916	−5.229	−20.347
ATOM	3457	H	ARG	319	−36.293	−5.783	−22.905
ATOM	3458	HB1	ARG	319	−36.73	−7.664	−19.824
ATOM	3459	HB2	ARG	319	−37.494	−7.316	−21.41
ATOM	3460	HG1	ARG	319	−35.281	−7.894	−22.548
ATOM	3461	HG2	ARG	319	−34.677	−8.479	−20.974
ATOM	3462	HD1	ARG	319	−36.444	−10.187	−20.881
ATOM	3463	HD2	ARG	319	−37.235	−9.457	−22.337
ATOM	3464	HE	ARG	319	−34.618	−10.226	−23.085
ATOM	3465	HH12	ARG	319	−37.546	−13.051	−23.251
ATOM	3466	HH11	ARG	319	−37.784	−11.707	−22.151
ATOM	3467	HH22	ARG	319	−35.666	−13.245	−24.492
ATOM	3468	HH21	ARG	319	−34.426	−11.991	−24.452
ATOM	3469	N	THR	320	−33.68	−6.042	−20.358
ATOM	3470	CA	THR	320	−32.505	−5.919	−19.496
ATOM	3471	C	THR	320	−32.203	−4.459	−19.23
ATOM	3472	O	THR	320	−31.839	−4.102	−18.119
ATOM	3473	CB	THR	320	−31.285	−6.602	−20.175
ATOM	3474	OG1	THR	320	−31.694	−7.934	−20.537
ATOM	3475	CG2	THR	320	−30.052	−6.663	−19.233
ATOM	3476	HA	THR	320	−32.72	−6.444	−18.553
ATOM	3477	H	THR	320	−33.557	−6.348	−21.306
ATOM	3478	HB	THR	320	−31.024	−6.04	−21.089
ATOM	3479	HG1	THR	320	−31.014	−8.424	−20.989
ATOM	3480	HG23	THR	320	−29.741	−5.661	−18.905
ATOM	3481	HG21	THR	320	−30.303	−7.264	−18.349
ATOM	3482	HG22	THR	320	−29.201	−7.136	−19.748
ATOM	3483	N	LYS	321	−32.349	−3.616	−20.277
ATOM	3484	CA	LYS	321	−32.026	−2.191	−20.182
ATOM	3485	C	LYS	321	−33.029	−1.457	−19.312
ATOM	3486	O	LYS	321	−32.638	−0.559	−18.581
ATOM	3487	CB	LYS	321	−31.939	−1.641	−21.639
ATOM	3488	CG	LYS	321	−31.273	−0.248	−21.783
ATOM	3489	CD	LYS	321	−30.932	0.05	−23.275
ATOM	3490	CE	LYS	321	−30.535	1.534	−23.507
ATOM	3491	NZ	LYS	321	−29.917	1.78	−24.832
ATOM	3492	HA	LYS	321	−31.039	−2.098	−19.711
ATOM	3493	H	LYS	321	−32.709	−3.962	−21.145
ATOM	3494	HB1	LYS	321	−31.338	−2.347	−22.233
ATOM	3495	HB2	LYS	321	−32.95	−1.605	−22.077
ATOM	3496	HG1	LYS	321	−31.968	0.499	−21.386
ATOM	3497	HG2	LYS	321	−30.352	−0.196	−21.184
ATOM	3498	HD1	LYS	321	−30.099	−0.602	−23.583
ATOM	3499	HD2	LYS	321	−31.799	−0.185	−23.914
ATOM	3500	HE1	LYS	321	−31.456	2.133	−23.444
ATOM	3501	HE2	LYS	321	−29.843	1.864	−22.712
ATOM	3502	HZ1	LYS	321	−30.563	1.468	−25.642
ATOM	3503	HZ2	LYS	321	−29.713	2.834	−24.982
ATOM	3504	HZ3	LYS	321	−28.975	1.261	−24.944
ATOM	3505	N	ARG	322	−34.329	−1.829	−19.359
ATOM	3506	CA	ARG	322	−35.317	−1.202	−18.474
ATOM	3507	C	ARG	322	−34.89	−1.402	−17.037
ATOM	3508	O	ARG	322	−34.783	−0.443	−16.29
ATOM	3509	CB	ARG	322	−36.763	−1.786	−18.621
ATOM	3510	CG	ARG	322	−37.833	−0.699	−18.923
ATOM	3511	CD	ARG	322	−39.258	−1.321	−18.948
ATOM	3512	NE	ARG	322	−40.286	−0.35	−19.338
ATOM	3513	CZ	ARG	322	−41.521	−0.685	−19.647
ATOM	3514	NH1	ARG	322	−41.96	−1.919	−19.581
ATOM	3515	NH2	ARG	322	−42.354	0.246	−20.045
ATOM	3516	HA	ARG	322	−35.324	−0.12	−18.681
ATOM	3517	H	ARG	322	−34.611	−2.554	−19.988
ATOM	3518	HB1	ARG	322	−36.805	−2.535	−19.426
ATOM	3519	HB2	ARG	322	−37.073	−2.304	−17.697
ATOM	3520	HG1	ARG	322	−37.797	0.091	−18.154
ATOM	3521	HG2	ARG	322	−37.615	−0.243	−19.904
ATOM	3522	HD1	ARG	322	−39.214	−2.155	−19.667
ATOM	3523	HD2	ARG	322	−39.501	−1.715	−17.947
ATOM	3524	HE	ARG	322	−40.004	0.641	−19.401
ATOM	3525	HH12	ARG	322	−42.929	−2.144	−19.859
ATOM	3526	HH11	ARG	322	−41.374	−2.692	−19.251
ATOM	3527	HH22	ARG	322	−43.333	0.011	−20.292
ATOM	3528	HH21	ARG	322	−42.064	1.231	−20.125
ATOM	3529	N	VAL	323	−34.658	−2.669	−16.63
ATOM	3530	CA	VAL	323	−34.31	−2.919	−15.232
ATOM	3531	C	VAL	323	−33.052	−2.15	−14.909
ATOM	3532	O	VAL	323	−32.969	−1.546	−13.852
ATOM	3533	CB	VAL	323	−34.127	−4.432	−14.926
ATOM	3534	CG1	VAL	323	−33.519	−4.638	−13.512
ATOM	3535	CG2	VAL	323	−35.474	−5.202	−15.034
ATOM	3536	HA	VAL	323	−35.119	−2.543	−14.587
ATOM	3537	H	VAL	323	−34.71	−3.434	−17.277
ATOM	3538	HB	VAL	323	−33.43	−4.844	−15.673
ATOM	3539	HG11	VAL	323	−34.175	−4.212	−12.739
ATOM	3540	HG12	VAL	323	−33.405	−5.711	−13.324
ATOM	3541	HG13	VAL	323	−32.525	−4.177	−13.422
ATOM	3542	HG21	VAL	323	−35.927	−5.086	−16.029
ATOM	3543	HG22	VAL	323	−35.313	−6.278	−14.86
ATOM	3544	HG23	VAL	323	−36.188	−4.832	−14.283
ATOM	3545	N	THR	324	−32.043	−2.143	−15.802
ATOM	3546	CA	THR	324	−30.842	−1.371	−15.499
ATOM	3547	C	THR	324	−31.18	0.079	−15.226
ATOM	3548	O	THR	324	−30.623	0.649	−14.3
ATOM	3549	CB	THR	324	−29.803	−1.573	−16.629
ATOM	3550	OG1	THR	324	−29.569	−2.995	−16.706
ATOM	3551	CG2	THR	324	−28.482	−0.81	−16.359
ATOM	3552	HA	THR	324	−30.418	−1.778	−14.572
ATOM	3553	H	THR	324	−32.102	−2.654	−16.666
ATOM	3554	HB	THR	324	−30.243	−1.197	−17.568
ATOM	3555	HG1	THR	324	−29.009	−3.232	−17.438
ATOM	3556	HG23	THR	324	−28.66	0.275	−16.324
ATOM	3557	HG21	THR	324	−28.037	−1.129	−15.405
ATOM	3558	HG22	THR	324	−27.771	−1.021	−17.172
ATOM	3559	N	ARG	325	−32.102	0.704	−15.991
ATOM	3560	CA	ARG	325	−32.516	2.063	−15.636
ATOM	3561	C	ARG	325	−33.137	2.083	−14.258
ATOM	3562	O	ARG	325	−32.883	3.028	−13.527
ATOM	3563	CB	ARG	325	−33.52	2.658	−16.661
ATOM	3564	CG	ARG	325	−34.029	4.076	−16.272
ATOM	3565	CD	ARG	325	−34.859	4.707	−17.427
ATOM	3566	NE	ARG	325	−35.452	5.998	−17.071
ATOM	3567	CZ	ARG	325	−36.207	6.701	−17.889
ATOM	3568	NH1	ARG	325	−36.505	6.306	−19.106
ATOM	3569	NH2	ARG	325	−36.687	7.849	−17.473
ATOM	3570	HA	ARG	325	−31.619	2.706	−15.625
ATOM	3571	H	ARG	325	−32.541	0.236	−16.763
ATOM	3572	HB1	ARG	325	−33.006	2.712	−17.63
ATOM	3573	HB2	ARG	325	−34.387	1.988	−16.769
ATOM	3574	HG1	ARG	325	−34.663	4.005	−15.372
ATOM	3575	HG2	ARG	325	−33.173	4.732	−16.042
ATOM	3576	HD1	ARG	325	−34.178	4.86	−18.278
ATOM	3577	HD2	ARG	325	−35.655	3.994	−17.698
ATOM	3578	HE	ARG	325	−35.254	6.362	−16.125
ATOM	3579	HH12	ARG	325	−37.099	6.882	−19.719
ATOM	3580	HH11	ARG	325	−36.165	5.416	−19.493
ATOM	3581	HH22	ARG	325	−37.282	8.431	−18.08
ATOM	3582	HH21	ARG	325	−36.483	8.204	−16.527
ATOM	3583	N	THR	326	−33.957	1.08	−13.87
ATOM	3584	CA	THR	326	−34.552	1.126	−12.534
ATOM	3585	C	THR	326	−33.442	1.08	−11.51
ATOM	3586	O	THR	326	−33.4	1.93	−10.636
ATOM	3587	CB	THR	326	−35.568	−0.006	−12.198
ATOM	3588	OG1	THR	326	−34.89	−1.271	−12.099
ATOM	3589	CG2	THR	326	−36.718	−0.098	−13.238
ATOM	3590	HA	THR	326	−35.085	2.087	−12.44
ATOM	3591	H	THR	326	−34.138	0.298	−14.468
ATOM	3592	HB	THR	326	−36.005	0.235	−11.21
ATOM	3593	HG1	THR	326	−35.464	−1.984	−11.839
ATOM	3594	HG23	THR	326	−37.147	0.895	−13.416
ATOM	3595	HG21	THR	326	−36.364	−0.489	−14.2
ATOM	3596	HG22	THR	326	−37.514	−0.766	−12.87
ATOM	3597	N	ALA	327	−32.527	0.09	−11.603
ATOM	3598	CA	ALA	327	−31.43	0.015	−10.639
ATOM	3599	C	ALA	327	−30.728	1.35	−10.518
ATOM	3600	O	ALA	327	−30.489	1.807	−9.41
ATOM	3601	CB	ALA	327	−30.377	−1.042	−11.066
ATOM	3602	HA	ALA	327	−31.843	−0.264	−9.656
ATOM	3603	H	ALA	327	−32.607	−0.606	−12.323
ATOM	3604	HB1	ALA	327	−29.564	−1.087	−10.324
ATOM	3605	HB2	ALA	327	−30.84	−2.037	−11.148
ATOM	3606	HB3	ALA	327	−29.945	−0.778	−12.043
ATOM	3607	N	ILE	328	−30.389	1.994	−11.658
ATOM	3608	CA	ILE	328	−29.706	3.287	−11.581
ATOM	3609	C	ILE	328	−30.634	4.27	−10.902
ATOM	3610	O	ILE	328	−30.197	4.987	−10.015
ATOM	3611	CB	ILE	328	−29.242	3.791	−12.983
ATOM	3612	CG1	ILE	328	−28.12	2.859	−13.545
ATOM	3613	CG2	ILE	328	−28.759	5.269	−12.901
ATOM	3614	CD1	ILE	328	−27.842	3.054	−15.061
ATOM	3615	HA	ILE	328	−28.809	3.176	−10.95
ATOM	3616	H	ILE	328	−30.638	1.615	−12.554
ATOM	3617	HB	ILE	328	−30.113	3.759	−13.658
ATOM	3618	HG11	ILE	328	−27.187	3.021	−12.982
ATOM	3619	HG12	ILE	328	−28.405	1.804	−13.408
ATOM	3620	HD11	ILE	328	−27.423	4.048	−15.273
ATOM	3621	HD12	ILE	328	−27.114	2.302	−15.408
ATOM	3622	HD13	ILE	328	−28.77	2.929	−15.64
ATOM	3623	HG21	ILE	328	−27.924	5.359	−12.188
ATOM	3624	HG22	ILE	328	−28.424	5.64	−13.88
ATOM	3625	HG23	ILE	328	−29.572	5.933	−12.57
ATOM	3626	N	ALA	329	−31.927	4.328	−11.288
ATOM	3627	CA	ALA	329	−32.831	5.274	−10.637
ATOM	3628	C	ALA	329	−32.82	5.074	−9.138
ATOM	3629	O	ALA	329	−32.783	6.059	−8.416
ATOM	3630	CB	ALA	329	−34.289	5.136	−11.149
ATOM	3631	HA	ALA	329	−32.477	6.294	−10.864
ATOM	3632	H	ALA	329	−32.28	3.732	−12.014
ATOM	3633	HB1	ALA	329	−34.929	5.898	−10.677
ATOM	3634	HB2	ALA	329	−34.324	5.273	−12.241
ATOM	3635	HB3	ALA	329	−34.694	4.144	−10.904
ATOM	3636	N	ILE	330	−32.844	3.817	−8.637
ATOM	3637	CA	ILE	330	−32.819	3.632	−7.186
ATOM	3638	C	ILE	330	−31.492	4.173	−6.695
ATOM	3639	O	ILE	330	−31.489	4.888	−5.706
ATOM	3640	CB	ILE	330	−33.052	2.176	−6.668
ATOM	3641	CG1	ILE	330	−34.386	1.577	−7.217
ATOM	3642	CG2	ILE	330	−33.084	2.163	−5.108
ATOM	3643	CD1	ILE	330	−34.658	0.12	−6.752
ATOM	3644	HA	ILE	330	−33.631	4.245	−6.762
ATOM	3645	H	ILE	330	−32.821	3.02	−9.246
ATOM	3646	HB	ILE	330	−32.208	1.559	−7.019
ATOM	3647	HG11	ILE	330	−35.231	2.21	−6.901
ATOM	3648	HG12	ILE	330	−34.37	1.561	−8.316
ATOM	3649	HD11	ILE	330	−34.907	0.076	−5.681
ATOM	3650	HD12	ILE	330	−35.513	−0.298	−7.308
ATOM	3651	HD13	ILE	330	−33.777	−0.511	−6.941
ATOM	3652	HG21	ILE	330	−34.016	2.618	−4.739
ATOM	3653	HG22	ILE	330	−33.018	1.135	−4.721
ATOM	3654	HG23	ILE	330	−32.25	2.724	−4.668
ATOM	3655	N	CYS	331	−30.351	3.871	−7.36
ATOM	3656	CA	CYS	331	−29.078	4.421	−6.888
ATOM	3657	C	CYS	331	−29.175	5.92	−6.709
ATOM	3658	O	CYS	331	−28.721	6.439	−5.7
ATOM	3659	CB	CYS	331	−27.875	4.161	−7.838
ATOM	3660	SG	CYS	331	−27.599	2.381	−8.118
ATOM	3661	HA	CYS	331	−28.865	3.967	−5.911
ATOM	3662	H	CYS	331	−30.358	3.276	−8.168
ATOM	3663	HB1	CYS	331	−28.034	4.653	−8.809
ATOM	3664	HB2	CYS	331	−26.961	4.576	−7.387
ATOM	3665	HG	CYS	331	−26.81	2.447	−8.743
ATOM	3666	LPG1	CYS	331	−27.443	2.053	−7.544
ATOM	3667	LPG2	CYS	331	−28.133	2.083	−8.411
ATOM	3668	N	LEU	332	−29.767	6.636	−7.69
ATOM	3669	CA	LEU	332	−29.861	8.089	−7.564
ATOM	3670	C	LEU	332	−30.753	8.44	−6.394
ATOM	3671	O	LEU	332	−30.376	9.276	−5.587
ATOM	3672	CB	LEU	332	−30.404	8.777	−8.849
ATOM	3673	CG	LEU	332	−29.567	8.519	−10.141
ATOM	3674	CD1	LEU	332	−30.204	9.282	−11.336
ATOM	3675	CD2	LEU	332	−28.075	8.927	−9.982
ATOM	3676	HA	LEU	332	−28.864	8.496	−7.338
ATOM	3677	H	LEU	332	−30.169	6.178	−8.487
ATOM	3678	HB1	LEU	332	−31.434	8.424	−9.021
ATOM	3679	HB2	LEU	332	−30.447	9.863	−8.664
ATOM	3680	HG	LEU	332	−29.592	7.448	−10.397
ATOM	3681	HD21	LEU	332	−27.555	8.261	−9.278
ATOM	3682	HD22	LEU	332	−27.552	8.855	−10.948
ATOM	3683	HD23	LEU	332	−27.997	9.964	−9.619
ATOM	3684	HD11	LEU	332	−30.173	10.368	−11.159
ATOM	3685	HD12	LEU	332	−29.662	9.064	−12.27
ATOM	3686	HD13	LEU	332	−31.254	8.978	−11.473
ATOM	3687	N	VAL	333	−31.943	7.811	−6.275
ATOM	3688	CA	VAL	333	−32.82	8.138	−5.15
ATOM	3689	C	VAL	333	−32.073	7.901	−3.857
ATOM	3690	O	VAL	333	−32.135	8.734	−2.965
ATOM	3691	CB	VAL	333	−34.142	7.311	−5.163
ATOM	3692	CG1	VAL	333	−34.924	7.469	−3.829
ATOM	3693	CG2	VAL	333	−35.053	7.74	−6.349
ATOM	3694	HA	VAL	333	−33.077	9.209	−5.204
ATOM	3695	H	VAL	333	−32.217	7.103	−6.932
ATOM	3696	HB	VAL	333	−33.887	6.244	−5.273
ATOM	3697	HG11	VAL	333	−35.126	8.534	−3.635
ATOM	3698	HG12	VAL	333	−35.882	6.932	−3.887
ATOM	3699	HG13	VAL	333	−34.36	7.056	−2.979
ATOM	3700	HG21	VAL	333	−34.539	7.634	−7.315
ATOM	3701	HG22	VAL	333	−35.96	7.118	−6.379
ATOM	3702	HG23	VAL	333	−35.358	8.791	−6.235
ATOM	3703	N	PHE	334	−31.361	6.763	−3.732
ATOM	3704	CA	PHE	334	−30.632	6.493	−2.496
ATOM	3705	C	PHE	334	−29.634	7.598	−2.234
ATOM	3706	O	PHE	334	−29.608	8.126	−1.133
ATOM	3707	CB	PHE	334	−29.903	5.127	−2.575
ATOM	3708	CG	PHE	334	−29.133	4.862	−1.274
ATOM	3709	CD1	PHE	334	−29.697	4.104	−0.24
ATOM	3710	CD2	PHE	334	−27.852	5.397	−1.108
ATOM	3711	CE1	PHE	334	−29.052	4.02	0.998
ATOM	3712	CE2	PHE	334	−27.204	5.311	0.127
ATOM	3713	CZ	PHE	334	−27.835	4.677	1.199
ATOM	3714	HA	PHE	334	−31.355	6.451	−1.663
ATOM	3715	H	PHE	334	−31.322	6.098	−4.481
ATOM	3716	HB1	PHE	334	−30.641	4.329	−2.757
ATOM	3717	HB2	PHE	334	−29.204	5.145	−3.425
ATOM	3718	HD2	PHE	334	−27.356	5.888	−1.937
ATOM	3719	HE2	PHE	334	−26.216	5.74	0.251
ATOM	3720	HZ	PHE	334	−27.38	4.698	2.184
ATOM	3721	HE1	PHE	334	−29.503	3.456	1.807
ATOM	3722	HD1	PHE	334	−30.64	3.589	−0.389
ATOM	3723	N	PHE	335	−28.796	7.972	−3.229
ATOM	3724	CA	PHE	335	−27.827	9.038	−2.98
ATOM	3725	C	PHE	335	−28.551	10.297	−2.555
ATOM	3726	O	PHE	335	−28.109	10.947	−1.621
ATOM	3727	CB	PHE	335	−26.956	9.375	−4.223
ATOM	3728	CG	PHE	335	−26.199	8.182	−4.839
ATOM	3729	CD1	PHE	335	−26.069	8.094	−6.23
ATOM	3730	CD2	PHE	335	−25.623	7.178	−4.049
ATOM	3731	CE1	PHE	335	−25.449	6.993	−6.826
ATOM	3732	CE2	PHE	335	−25.043	6.05	−4.64
ATOM	3733	CZ	PHE	335	−24.934	5.967	−6.03
ATOM	3734	HA	PHE	335	−27.181	8.737	−2.139
ATOM	3735	H	PHE	335	−28.832	7.544	−4.138
ATOM	3736	HB1	PHE	335	−27.625	9.808	−4.983
ATOM	3737	HB2	PHE	335	−26.209	10.138	−3.952
ATOM	3738	HD2	PHE	335	−25.606	7.261	−2.971
ATOM	3739	HE2	PHE	335	−24.673	5.24	−4.02
ATOM	3740	HZ	PHE	335	−24.448	5.112	−6.488
ATOM	3741	HE1	PHE	335	−25.366	6.934	−7.907
ATOM	3742	HD1	PHE	335	−26.445	8.89	−6.865
ATOM	3743	N	VAL	336	−29.666	10.67	−3.219
ATOM	3744	CA	VAL	336	−30.373	11.888	−2.818
ATOM	3745	C	VAL	336	−30.892	11.739	−1.404
ATOM	3746	O	VAL	336	−30.784	12.674	−0.627
ATOM	3747	CB	VAL	336	−31.547	12.226	−3.786
ATOM	3748	CG1	VAL	336	−32.449	13.362	−3.222
ATOM	3749	CG2	VAL	336	−31.005	12.641	−5.184
ATOM	3750	HA	VAL	336	−29.663	12.731	−2.828
ATOM	3751	H	VAL	336	−30.031	10.104	−3.965
ATOM	3752	HB	VAL	336	−32.177	11.328	−3.901
ATOM	3753	HG11	VAL	336	−31.846	14.259	−3.012
ATOM	3754	HG12	VAL	336	−33.231	13.629	−3.951
ATOM	3755	HG13	VAL	336	−32.953	13.051	−2.294
ATOM	3756	HG21	VAL	336	−30.348	11.871	−5.61
ATOM	3757	HG22	VAL	336	−31.839	12.801	−5.885
ATOM	3758	HG23	VAL	336	−30.432	13.578	−5.108
ATOM	3759	N	CYS	337	−31.48	10.579	−1.045
ATOM	3760	CA	CYS	337	−32.057	10.444	0.292
ATOM	3761	C	CYS	337	−30.991	10.482	1.366
ATOM	3762	O	CYS	337	−31.207	11.122	2.384
ATOM	3763	CB	CYS	337	−32.861	9.122	0.408
ATOM	3764	SG	CYS	337	−33.699	9.051	2.027
ATOM	3765	HA	CYS	337	−32.761	11.278	0.455
ATOM	3766	H	CYS	337	−31.54	9.811	−1.688
ATOM	3767	HB1	CYS	337	−33.622	9.079	−0.388
ATOM	3768	HB2	CYS	337	−32.19	8.255	0.303
ATOM	3769	HG	CYS	337	−34.217	8.199	1.881
ATOM	3770	LPG1	CYS	337	−33.26	9	2.542
ATOM	3771	LPG2	CYS	337	−34.106	9.585	2.129
ATOM	3772	N	TRP	338	−29.845	9.788	1.172
ATOM	3773	CA	TRP	338	−28.853	9.657	2.247
ATOM	3774	C	TRP	338	−27.654	10.573	2.147
ATOM	3775	O	TRP	338	−27.08	10.867	3.186
ATOM	3776	CB	TRP	338	−28.351	8.194	2.264
ATOM	3777	CG	TRP	338	−29.496	7.31	2.671
ATOM	3778	CD1	TRP	338	−30.281	6.56	1.885
ATOM	3779	CD2	TRP	338	−29.974	7.115	4.086
ATOM	3780	NE1	TRP	338	−31.14	5.904	2.623
ATOM	3781	CE2	TRP	338	−30.989	6.189	3.933
ATOM	3782	CE3	TRP	338	−29.614	7.635	5.327
ATOM	3783	CZ2	TRP	338	−31.684	5.689	5.032
ATOM	3784	CZ3	TRP	338	−30.329	7.165	6.435
ATOM	3785	CH2	TRP	338	−31.352	6.215	6.287
ATOM	3786	HA	TRP	338	−29.316	9.855	3.229
ATOM	3787	H	TRP	338	−29.684	9.316	0.3
ATOM	3788	HB1	TRP	338	−27.958	7.908	1.276
ATOM	3789	HB2	TRP	338	−27.542	8.074	2.999
ATOM	3790	HE1	TRP	338	−31.843	5.246	2.249
ATOM	3791	HD1	TRP	338	−30.201	6.512	0.801
ATOM	3792	HZ2	TRP	338	−32.443	4.923	4.922
ATOM	3793	HH2	TRP	338	−31.895	5.875	7.163
ATOM	3794	HZ3	TRP	338	−30.086	7.539	7.424
ATOM	3795	HE3	TRP	338	−28.82	8.367	5.426
ATOM	3796	N	ALA	339	−27.234	11.04	0.949
ATOM	3797	CA	ALA	339	−26.059	11.908	0.891
ATOM	3798	C	ALA	339	−26.173	13.063	1.865
ATOM	3799	O	ALA	339	−25.174	13.334	2.515
ATOM	3800	CB	ALA	339	−25.691	12.405	−0.533
ATOM	3801	HA	ALA	339	−25.203	11.294	1.213
ATOM	3802	H	ALA	339	−27.698	10.799	0.094
ATOM	3803	HB1	ALA	339	−24.759	12.992	−0.492
ATOM	3804	HB2	ALA	339	−25.529	11.545	−1.201
ATOM	3805	HB3	ALA	339	−26.473	13.04	−0.968
ATOM	3806	N	PRO	340	−27.318	13.773	2.04
ATOM	3807	CA	PRO	340	−27.347	14.843	3.025
ATOM	3808	C	PRO	340	−26.896	14.389	4.393
ATOM	3809	O	PRO	340	−26.103	15.086	5.007
ATOM	3810	CB	PRO	340	−28.85	15.221	2.995
ATOM	3811	CG	PRO	340	−29.273	14.861	1.552
ATOM	3812	CD	PRO	340	−28.548	13.519	1.3
ATOM	3813	HA	PRO	340	−26.728	15.679	2.659
ATOM	3814	HD2	PRO	340	−28.427	13.331	0.225
ATOM	3815	HD1	PRO	340	−29.121	12.704	1.766
ATOM	3816	HG2	PRO	340	−28.88	15.625	0.861
ATOM	3817	HG1	PRO	340	−30.366	14.79	1.421
ATOM	3818	HB1	PRO	340	−29.423	14.588	3.693
ATOM	3819	HB2	PRO	340	−29.03	16.278	3.249
ATOM	3820	N	TYR	341	−27.377	13.231	4.903
ATOM	3821	CA	TYR	341	−26.961	12.836	6.244
ATOM	3822	C	TYR	341	−25.511	12.418	6.225
ATOM	3823	O	TYR	341	−24.817	12.75	7.171
ATOM	3824	CB	TYR	341	−27.803	11.72	6.921
ATOM	3825	CG	TYR	341	−27.276	11.54	8.357
ATOM	3826	CD1	TYR	341	−27.327	12.608	9.26
ATOM	3827	CD2	TYR	341	−26.71	10.333	8.781
ATOM	3828	CE1	TYR	341	−26.538	12.592	10.414
ATOM	3829	CE2	TYR	341	−26.004	10.283	9.988
ATOM	3830	CZ	TYR	341	−25.798	11.448	10.732
ATOM	3831	OH	TYR	341	−24.861	11.448	11.769
ATOM	3832	HA	TYR	341	−27.046	13.737	6.873
ATOM	3833	H	TYR	341	−27.979	12.625	4.379
ATOM	3834	HB2	TYR	341	−28.867	11.998	6.954
ATOM	3835	HB1	TYR	341	−27.708	10.793	6.334
ATOM	3836	HD2	TYR	341	−26.805	9.436	8.177
ATOM	3837	HE2	TYR	341	−25.606	9.342	10.348
ATOM	3838	HE1	TYR	341	−26.501	13.469	11.051
ATOM	3839	HD1	TYR	341	−27.968	13.462	9.068
ATOM	3840	HH	TYR	341	−24.808	12.263	12.262
ATOM	3841	N	TYR	342	−25.007	11.705	5.191
ATOM	3842	CA	TYR	342	−23.573	11.408	5.184
ATOM	3843	C	TYR	342	−22.788	12.702	5.252
ATOM	3844	O	TYR	342	−21.801	12.76	5.968
ATOM	3845	CB	TYR	342	−23.08	10.622	3.939
ATOM	3846	CG	TYR	342	−23.456	9.132	3.991
ATOM	3847	CD1	TYR	342	−24.364	8.577	3.083
ATOM	3848	CD2	TYR	342	−22.865	8.3	4.95
ATOM	3849	CE1	TYR	342	−24.629	7.204	3.09
ATOM	3850	CE2	TYR	342	−23.138	6.929	4.966
ATOM	3851	CZ	TYR	342	−24.022	6.373	4.039
ATOM	3852	OH	TYR	342	−24.289	5.001	4.082
ATOM	3853	HA	TYR	342	−23.344	10.82	6.086
ATOM	3854	H	TYR	342	−25.58	11.409	4.421
ATOM	3855	HB2	TYR	342	−23.454	11.109	3.026
ATOM	3856	HB1	TYR	342	−21.979	10.661	3.904
ATOM	3857	HD2	TYR	342	−22.185	8.714	5.687
ATOM	3858	HE2	TYR	342	−22.661	6.29	5.701
ATOM	3859	HE1	TYR	342	−25.31	6.792	2.355
ATOM	3860	HD1	TYR	342	−24.87	9.205	2.36
ATOM	3861	HH	TYR	342	−24.843	4.677	3.38
ATOM	3862	N	VAL	343	−23.189	13.765	4.522
ATOM	3863	CA	VAL	343	−22.43	15.013	4.618
ATOM	3864	C	VAL	343	−22.476	15.502	6.049
ATOM	3865	O	VAL	343	−21.431	15.755	6.629
ATOM	3866	CB	VAL	343	−22.945	16.108	3.635
ATOM	3867	CG1	VAL	343	−22.311	17.494	3.946
ATOM	3868	CG2	VAL	343	−22.638	15.71	2.162
ATOM	3869	HA	VAL	343	−21.376	14.805	4.368
ATOM	3870	H	VAL	343	−24.008	13.718	3.944
ATOM	3871	HB	VAL	343	−24.038	16.206	3.751
ATOM	3872	HG11	VAL	343	−21.212	17.427	3.916
ATOM	3873	HG12	VAL	343	−22.637	18.239	3.204
ATOM	3874	HG13	VAL	343	−22.613	17.857	4.94
ATOM	3875	HG21	VAL	343	−23.06	14.725	1.916
ATOM	3876	HG22	VAL	343	−23.07	16.448	1.469
ATOM	3877	HG23	VAL	343	−21.551	15.669	1.995
ATOM	3878	N	LEU	344	−23.68	15.648	6.646
ATOM	3879	CA	LEU	344	−23.744	16.182	8.007
ATOM	3880	C	LEU	344	−22.959	15.3	8.957
ATOM	3881	O	LEU	344	−22.234	15.817	9.796
ATOM	3882	CB	LEU	344	−25.193	16.299	8.55
ATOM	3883	CG	LEU	344	−26.122	17.292	7.787
ATOM	3884	CD1	LEU	344	−27.535	17.236	8.426
ATOM	3885	CD2	LEU	344	−25.611	18.76	7.815
ATOM	3886	HA	LEU	344	−23.28	17.178	8.003
ATOM	3887	H	LEU	344	−24.523	15.39	6.167
ATOM	3888	HB1	LEU	344	−25.634	15.29	8.53
ATOM	3889	HB2	LEU	344	−25.149	16.625	9.598
ATOM	3890	HG	LEU	344	−26.214	16.98	6.735
ATOM	3891	HD21	LEU	344	−24.675	18.878	7.251
ATOM	3892	HD22	LEU	344	−26.355	19.428	7.354
ATOM	3893	HD23	LEU	344	−25.45	19.086	8.855
ATOM	3894	HD11	LEU	344	−27.526	17.691	9.428
ATOM	3895	HD12	LEU	344	−28.262	17.77	7.798
ATOM	3896	HD13	LEU	344	−27.863	16.192	8.52
ATOM	3897	N	GLN	345	−23.099	13.962	8.834
ATOM	3898	CA	GLN	345	−22.324	13.039	9.664
ATOM	3899	C	GLN	345	−20.859	13.403	9.588
ATOM	3900	O	GLN	345	−20.206	13.525	10.614
ATOM	3901	CB	GLN	345	−22.485	11.586	9.125
ATOM	3902	CG	GLN	345	−21.648	10.519	9.877
ATOM	3903	CD	GLN	345	−21.554	9.274	9.021
ATOM	3904	OE1	GLN	345	−20.548	9.081	8.356
ATOM	3905	NE2	GLN	345	−22.586	8.408	8.991
ATOM	3906	HA	GLN	345	−22.677	13.092	10.707
ATOM	3907	H	GLN	345	−23.726	13.586	8.152
ATOM	3908	HB1	GLN	345	−23.546	11.294	9.141
ATOM	3909	HB2	GLN	345	−22.154	11.568	8.079
ATOM	3910	HG1	GLN	345	−20.624	10.875	10.069
ATOM	3911	HG2	GLN	345	−22.118	10.305	10.848
ATOM	3912	HE22	GLN	345	−22.525	7.593	8.416
ATOM	3913	HE21	GLN	345	−23.402	8.556	9.545
ATOM	3914	N	LEU	346	−20.322	13.559	8.359
ATOM	3915	CA	LEU	346	−18.885	13.776	8.223
ATOM	3916	C	LEU	346	−18.508	15.143	8.745
ATOM	3917	O	LEU	346	−17.413	15.27	9.27
ATOM	3918	CB	LEU	346	−18.414	13.572	6.757
ATOM	3919	CG	LEU	346	−18.583	12.101	6.256
ATOM	3920	CD1	LEU	346	−18.507	12.061	4.705
ATOM	3921	CD2	LEU	346	−17.522	11.134	6.857
ATOM	3922	HA	LEU	346	−18.364	13.045	8.859
ATOM	3923	H	LEU	346	−20.892	13.539	7.531
ATOM	3924	HB1	LEU	346	−19.004	14.261	6.131
ATOM	3925	HB2	LEU	346	−17.356	13.863	6.665
ATOM	3926	HG	LEU	346	−19.575	11.716	6.547
ATOM	3927	HD21	LEU	346	−17.615	11.045	7.949
ATOM	3928	HD22	LEU	346	−17.647	10.124	6.436
ATOM	3929	HD23	LEU	346	−16.505	11.482	6.62
ATOM	3930	HD11	LEU	346	−17.532	12.437	4.359
ATOM	3931	HD12	LEU	346	−18.636	11.032	4.339
ATOM	3932	HD13	LEU	346	−19.303	12.68	4.26
ATOM	3933	N	THR	347	−19.367	16.184	8.65
ATOM	3934	CA	THR	347	−18.992	17.449	9.285
ATOM	3935	C	THR	347	−18.784	17.187	10.759
ATOM	3936	O	THR	347	−17.807	17.673	11.305
ATOM	3937	CB	THR	347	−19.992	18.639	9.17
ATOM	3938	OG1	THR	347	−21.177	18.435	9.953
ATOM	3939	CG2	THR	347	−20.347	18.995	7.702
ATOM	3940	HA	THR	347	−18.037	17.776	8.839
ATOM	3941	H	THR	347	−20.258	16.091	8.2
ATOM	3942	HB	THR	347	−19.507	19.524	9.619
ATOM	3943	HG1	THR	347	−21.667	17.672	9.673
ATOM	3944	HG23	THR	347	−19.433	19.185	7.12
ATOM	3945	HG21	THR	347	−20.912	18.187	7.218
ATOM	3946	HG22	THR	347	−20.971	19.902	7.684
ATOM	3947	N	GLN	348	−19.676	16.422	11.432
ATOM	3948	CA	GLN	348	−19.492	16.21	12.867
ATOM	3949	C	GLN	348	−18.185	15.487	13.104
ATOM	3950	O	GLN	348	−17.487	15.836	14.042
ATOM	3951	CB	GLN	348	−20.673	15.439	13.526
ATOM	3952	CG	GLN	348	−20.609	15.516	15.077
ATOM	3953	CD	GLN	348	−21.761	14.852	15.787
ATOM	3954	OE1	GLN	348	−21.524	13.933	16.555
ATOM	3955	NE2	GLN	348	−23.018	15.297	15.574
ATOM	3956	HA	GLN	348	−19.431	17.209	13.33
ATOM	3957	H	GLN	348	−20.453	15.989	10.968
ATOM	3958	HB1	GLN	348	−21.611	15.902	13.19
ATOM	3959	HB2	GLN	348	−20.672	14.388	13.195
ATOM	3960	HG1	GLN	348	−19.664	15.067	15.421
ATOM	3961	HG2	GLN	348	−20.636	16.565	15.398
ATOM	3962	HE22	GLN	348	−23.783	14.856	16.045
ATOM	3963	HE21	GLN	348	−23.215	16.063	14.965
ATOM	3964	N	LEU	349	−17.818	14.483	12.274
ATOM	3965	CA	LEU	349	−16.508	13.852	12.451
ATOM	3966	C	LEU	349	−15.428	14.903	12.332
ATOM	3967	O	LEU	349	−14.573	14.988	13.2
ATOM	3968	CB	LEU	349	−16.224	12.749	11.391
ATOM	3969	CG	LEU	349	−14.781	12.156	11.455
ATOM	3970	CD1	LEU	349	−14.526	11.417	12.797
ATOM	3971	CD2	LEU	349	−14.532	11.195	10.259
ATOM	3972	HA	LEU	349	−16.48	13.406	13.458
ATOM	3973	H	LEU	349	−18.417	14.183	11.526
ATOM	3974	HB1	LEU	349	−16.966	11.945	11.513
ATOM	3975	HB2	LEU	349	−16.365	13.182	10.39
ATOM	3976	HG	LEU	349	−14.036	12.964	11.355
ATOM	3977	HD21	LEU	349	−14.694	11.712	9.3
ATOM	3978	HD22	LEU	349	−13.499	10.813	10.272
ATOM	3979	HD23	LEU	349	−15.216	10.341	10.313
ATOM	3980	HD11	LEU	349	−15.345	10.718	13.019
ATOM	3981	HD12	LEU	349	−13.588	10.845	12.741
ATOM	3982	HD13	LEU	349	−14.446	12.131	13.63
ATOM	3983	N	SER	350	−15.439	15.705	11.245
ATOM	3984	CA	SER	350	−14.368	16.679	11.05
ATOM	3985	C	SER	350	−14.322	17.682	12.18
ATOM	3986	O	SER	350	−13.236	18.053	12.597
ATOM	3987	CB	SER	350	−14.567	17.442	9.716
ATOM	3988	OG	SER	350	−14.578	16.486	8.641
ATOM	3989	HA	SER	350	−13.407	16.14	11
ATOM	3990	H	SER	350	−16.162	15.634	10.551
ATOM	3991	HB1	SER	350	−15.524	17.987	9.746
ATOM	3992	HB2	SER	350	−13.748	18.169	9.576
ATOM	3993	HG	SER	350	−14.717	16.887	7.788
ATOM	3994	N	ILE	351	−15.492	18.139	12.677
ATOM	3995	CA	ILE	351	−15.523	19.174	13.709
ATOM	3996	C	ILE	351	−16.68	18.877	14.644
ATOM	3997	O	ILE	351	−17.757	19.415	14.449
ATOM	3998	CB	ILE	351	−15.615	20.593	13.057
ATOM	3999	CG1	ILE	351	−16.6	20.621	11.846
ATOM	4000	CG2	ILE	351	−14.208	21.098	12.62
ATOM	4001	CD1	ILE	351	−17.067	22.048	11.448
ATOM	4002	HA	ILE	351	−14.622	19.135	14.342
ATOM	4003	H	ILE	351	−16.368	17.806	12.319
ATOM	4004	HB	ILE	351	−15.98	21.283	13.837
ATOM	4005	HG11	ILE	351	−16.137	20.136	10.972
ATOM	4006	HG12	ILE	351	−17.503	20.05	12.09
ATOM	4007	HD11	ILE	351	−16.231	22.659	11.079
ATOM	4008	HD12	ILE	351	−17.819	21.983	10.646
ATOM	4009	HD13	ILE	351	−17.526	22.556	12.311
ATOM	4010	HG21	ILE	351	−13.809	20.476	11.805
ATOM	4011	HG22	ILE	351	−14.25	22.139	12.27
ATOM	4012	HG23	ILE	351	−13.5	21.065	13.462
ATOM	4013	N	SER	352	−16.507	18.019	15.677
ATOM	4014	CA	SER	352	−17.638	17.728	16.559
ATOM	4015	C	SER	352	−18.236	19	17.121
ATOM	4016	O	SER	352	−17.529	19.99	17.206
ATOM	4017	CB	SER	352	−17.294	16.762	17.722
ATOM	4018	OG	SER	352	−18.465	16.4	18.482
ATOM	4019	HA	SER	352	−18.398	17.242	15.935
ATOM	4020	H	SER	352	−15.635	17.552	15.831
ATOM	4021	HB1	SER	352	−16.802	15.855	17.331
ATOM	4022	HB2	SER	352	−16.589	17.268	18.401
ATOM	4023	HG	SER	352	−19.08	15.872	17.982
ATOM	4024	N	ARG	353	−19.536	18.999	17.499
ATOM	4025	CA	ARG	353	−20.191	20.246	17.899
ATOM	4026	C	ARG	353	−20.079	21.274	16.789
ATOM	4027	O	ARG	353	−19.596	22.363	17.056
ATOM	4028	CB	ARG	353	−19.625	20.738	19.264
ATOM	4029	CG	ARG	353	−19.496	19.602	20.32
ATOM	4030	CD	ARG	353	−20.844	18.895	20.638
ATOM	4031	NE	ARG	353	−20.696	17.879	21.684
ATOM	4032	CZ	ARG	353	−21.678	17.105	22.094
ATOM	4033	NH1	ARG	353	−22.892	17.176	21.602
ATOM	4034	NH2	ARG	353	−21.44	16.223	23.036
ATOM	4035	HA	ARG	353	−21.274	20.09	18.033
ATOM	4036	H	ARG	353	−20.076	18.156	17.483
ATOM	4037	HB1	ARG	353	−18.62	21.165	19.115
ATOM	4038	HB2	ARG	353	−20.268	21.543	19.656
ATOM	4039	HG1	ARG	353	−18.769	18.85	19.971
ATOM	4040	HG2	ARG	353	−19.102	20.041	21.252
ATOM	4041	HD1	ARG	353	−21.57	19.662	20.958
ATOM	4042	HD2	ARG	353	−21.201	18.407	19.72
ATOM	4043	HE	ARG	353	−19.759	17.772	22.11
ATOM	4044	HH12	ARG	353	−23.641	16.556	21.942
ATOM	4045	HH11	ARG	353	−23.139	17.847	20.866
ATOM	4046	HH22	ARG	353	−22.184	15.602	23.386
ATOM	4047	HH21	ARG	353	−20.504	16.131	23.458
ATOM	4048	N	PRO	354	−20.5	20.99	15.53
ATOM	4049	CA	PRO	354	−20.286	21.953	14.456
ATOM	4050	C	PRO	354	−21.34	23.04	14.451
ATOM	4051	O	PRO	354	−22.253	22.988	15.259
ATOM	4052	CB	PRO	354	−20.466	20.999	13.252
ATOM	4053	CG	PRO	354	−21.58	20.04	13.728
ATOM	4054	CD	PRO	354	−21.126	19.724	15.171
ATOM	4055	HA	PRO	354	−19.274	22.389	14.477
ATOM	4056	HD2	PRO	354	−20.364	18.934	15.135
ATOM	4057	HD1	PRO	354	−21.973	19.425	15.81
ATOM	4058	HG2	PRO	354	−21.682	19.142	13.096
ATOM	4059	HG1	PRO	354	−22.543	20.576	13.749
ATOM	4060	HB1	PRO	354	−20.668	21.514	12.308
ATOM	4061	HB2	PRO	354	−19.559	20.401	13.111
ATOM	4062	N	THR	355	−21.221	24.033	13.536
ATOM	4063	CA	THR	355	−22.145	25.171	13.517
ATOM	4064	C	THR	355	−22.791	25.268	12.15
ATOM	4065	O	THR	355	−22.122	25.71	11.231
ATOM	4066	CB	THR	355	−21.334	26.457	13.839
ATOM	4067	OG1	THR	355	−20.73	26.279	15.134
ATOM	4068	CG2	THR	355	−22.241	27.717	13.845
ATOM	4069	HA	THR	355	−22.922	25.087	14.293
ATOM	4070	H	THR	355	−20.473	24.032	12.869
ATOM	4071	HB	THR	355	−20.539	26.581	13.082
ATOM	4072	HG1	THR	355	−20.18	27.011	15.397
ATOM	4073	HG23	THR	355	−22.719	27.865	12.864
ATOM	4074	HG21	THR	355	−23.024	27.615	14.61
ATOM	4075	HG22	THR	355	−21.642	28.612	14.074
ATOM	4076	N	LEU	356	−24.075	24.873	11.976
ATOM	4077	CA	LEU	356	−24.703	24.953	10.655
ATOM	4078	C	LEU	356	−26.204	24.793	10.778
ATOM	4079	O	LEU	356	−26.737	23.81	10.295
ATOM	4080	CB	LEU	356	−24.091	23.98	9.598
ATOM	4081	CG	LEU	356	−24.039	22.458	9.954
ATOM	4082	CD1	LEU	356	−23.507	21.667	8.723
ATOM	4083	CD2	LEU	356	−23.122	22.163	11.169
ATOM	4084	HA	LEU	356	−24.558	25.977	10.267
ATOM	4085	H	LEU	356	−24.617	24.518	12.739
ATOM	4086	HB1	LEU	356	−24.676	24.099	8.671
ATOM	4087	HB2	LEU	356	−23.065	24.308	9.37
ATOM	4088	HG	LEU	356	−25.04	22.068	10.195
ATOM	4089	HD21	LEU	356	−23.582	22.458	12.12
ATOM	4090	HD22	LEU	356	−22.909	21.085	11.237
ATOM	4091	HD23	LEU	356	−22.177	22.708	11.037
ATOM	4092	HD11	LEU	356	−22.5	22.018	8.449
ATOM	4093	HD12	LEU	356	−23.444	20.59	8.94
ATOM	4094	HD13	LEU	356	−24.171	21.8	7.855
ATOM	4095	N	THR	357	−26.921	25.745	11.421
ATOM	4096	CA	THR	357	−28.376	25.597	11.55
ATOM	4097	C	THR	357	−28.65	24.203	12.086
ATOM	4098	O	THR	357	−29.466	23.457	11.569
ATOM	4099	CB	THR	357	−28.988	25.987	10.175
ATOM	4100	OG1	THR	357	−28.499	27.306	9.867
ATOM	4101	CG2	THR	357	−30.538	26.002	10.183
ATOM	4102	HA	THR	357	−28.764	26.306	12.3
ATOM	4103	HB	THR	357	−28.629	25.286	9.404
ATOM	4104	HG1	THR	357	−28.776	27.622	9.012
ATOM	4105	HG23	THR	357	−30.929	24.996	10.373
ATOM	4106	HG21	THR	357	−30.912	26.686	10.96
ATOM	4107	HG22	THR	357	−30.921	26.335	9.206
ATOM	4108	H	THR	357	−26.483	26.568	11.79
ATOM	4109	N	PHE	358	−27.894	23.841	13.148
ATOM	4110	CA	PHE	358	−27.779	22.44	13.548
ATOM	4111	C	PHE	358	−29.102	21.725	13.739
ATOM	4112	O	PHE	358	−29.359	20.764	13.031
ATOM	4113	CB	PHE	358	−26.906	22.336	14.831
ATOM	4114	CG	PHE	358	−26.846	20.894	15.348
ATOM	4115	CD1	PHE	358	−25.851	20.016	14.902
ATOM	4116	CD2	PHE	358	−27.788	20.447	16.279
ATOM	4117	CE1	PHE	358	−25.833	18.69	15.344
ATOM	4118	CE2	PHE	358	−27.798	19.114	16.69
ATOM	4119	CZ	PHE	358	−26.815	18.235	16.228
ATOM	4120	HA	PHE	358	−27.232	21.919	12.743
ATOM	4121	HB1	PHE	358	−25.883	22.692	14.62
ATOM	4122	HB2	PHE	358	−27.318	22.986	15.619
ATOM	4123	HD2	PHE	358	−28.519	21.132	16.69
ATOM	4124	HE2	PHE	358	−28.571	18.768	17.368
ATOM	4125	HZ	PHE	358	−26.816	17.203	16.557
ATOM	4126	HE1	PHE	358	−25.058	18.012	14.999
ATOM	4127	HD1	PHE	358	−25.091	20.363	14.212
ATOM	4128	H	PHE	358	−27.294	24.512	13.589
ATOM	4129	N	VAL	359	−29.959	22.135	14.701
ATOM	4130	CA	VAL	359	−31.115	21.296	15.025
ATOM	4131	C	VAL	359	−31.951	21.017	13.798
ATOM	4132	O	VAL	359	−32.408	19.894	13.648
ATOM	4133	CB	VAL	359	−32.042	21.822	16.166
ATOM	4134	CG1	VAL	359	−31.298	21.899	17.53
ATOM	4135	CG2	VAL	359	−32.71	23.184	15.827
ATOM	4136	HA	VAL	359	−30.714	20.323	15.359
ATOM	4137	H	VAL	359	−29.774	22.961	15.231
ATOM	4138	HB	VAL	359	−32.855	21.084	16.296
ATOM	4139	HG11	VAL	359	−30.5	22.656	17.507
ATOM	4140	HG12	VAL	359	−32.002	22.17	18.332
ATOM	4141	HG13	VAL	359	−30.855	20.924	17.785
ATOM	4142	HG21	VAL	359	−33.363	23.095	14.946
ATOM	4143	HG22	VAL	359	−33.336	23.519	16.669
ATOM	4144	HG23	VAL	359	−31.955	23.959	15.631
ATOM	4145	N	TYR	360	−32.18	22.009	12.908
ATOM	4146	CA	TYR	360	−33.076	21.759	11.784
ATOM	4147	C	TYR	360	−32.391	20.936	10.721
ATOM	4148	O	TYR	360	−33.032	20.033	10.208
ATOM	4149	CB	TYR	360	−33.65	23.053	11.157
ATOM	4150	CG	TYR	360	−34.614	22.674	10.022
ATOM	4151	CD1	TYR	360	−35.882	22.167	10.322
ATOM	4152	CD2	TYR	360	−34.236	22.819	8.683
ATOM	4153	CE1	TYR	360	−36.74	21.75	9.3
ATOM	4154	CE2	TYR	360	−35.091	22.399	7.66
ATOM	4155	CZ	TYR	360	−36.341	21.853	7.961
ATOM	4156	OH	TYR	360	−37.166	21.421	6.918
ATOM	4157	HA	TYR	360	−33.945	21.192	12.158
ATOM	4158	H	TYR	360	−31.744	22.907	12.996
ATOM	4159	HB2	TYR	360	−34.186	23.638	11.921
ATOM	4160	HB1	TYR	360	−32.826	23.669	10.776
ATOM	4161	HD2	TYR	360	−33.278	23.255	8.429
ATOM	4162	HE2	TYR	360	−34.784	22.494	6.624
ATOM	4163	HE1	TYR	360	−37.714	21.346	9.555
ATOM	4164	HD1	TYR	360	−36.208	22.091	11.355
ATOM	4165	HH	TYR	360	−37.977	21.014	7.202
ATOM	4166	N	LEU	361	−31.116	21.195	10.35
ATOM	4167	CA	LEU	361	−30.508	20.356	9.315
ATOM	4168	C	LEU	361	−30.431	18.928	9.811
ATOM	4169	O	LEU	361	−30.751	18.018	9.061
ATOM	4170	CB	LEU	361	−29.08	20.778	8.867
ATOM	4171	CG	LEU	361	−28.94	22.228	8.317
ATOM	4172	CD1	LEU	361	−27.524	22.421	7.704
ATOM	4173	CD2	LEU	361	−30.014	22.586	7.255
ATOM	4174	HA	LEU	361	−31.166	20.356	8.43
ATOM	4175	H	LEU	361	−30.576	21.92	10.786
ATOM	4176	HB1	LEU	361	−28.386	20.647	9.714
ATOM	4177	HB2	LEU	361	−28.771	20.092	8.065
ATOM	4178	HG	LEU	361	−29.049	22.926	9.159
ATOM	4179	HD21	LEU	361	−31.015	22.614	7.706
ATOM	4180	HD22	LEU	361	−29.813	23.583	6.831
ATOM	4181	HD23	LEU	361	−30.009	21.849	6.439
ATOM	4182	HD11	LEU	361	−27.42	21.836	6.778
ATOM	4183	HD12	LEU	361	−27.343	23.482	7.468
ATOM	4184	HD13	LEU	361	−26.749	22.086	8.407
ATOM	4185	N	TYR	362	−30.007	18.702	11.074
ATOM	4186	CA	TYR	362	−29.919	17.328	11.566
ATOM	4187	C	TYR	362	−31.317	16.757	11.679
ATOM	4188	O	TYR	362	−31.546	15.68	11.153
ATOM	4189	CB	TYR	362	−29.114	17.209	12.891
ATOM	4190	CG	TYR	362	−27.597	17.243	12.616
ATOM	4191	CD1	TYR	362	−26.939	18.446	12.334
ATOM	4192	CD2	TYR	362	−26.845	16.061	12.637
ATOM	4193	CE1	TYR	362	−25.567	18.47	12.064
ATOM	4194	CE2	TYR	362	−25.465	16.084	12.411
ATOM	4195	CZ	TYR	362	−24.822	17.29	12.111
ATOM	4196	OH	TYR	362	−23.452	17.332	11.852
ATOM	4197	HA	TYR	362	−29.386	16.712	10.823
ATOM	4198	H	TYR	362	−29.798	19.465	11.692
ATOM	4199	HB2	TYR	362	−29.373	16.251	13.37
ATOM	4200	HB1	TYR	362	−29.393	18.012	13.591
ATOM	4201	HD2	TYR	362	−27.331	15.112	12.829
ATOM	4202	HE2	TYR	362	−24.892	15.165	12.464
ATOM	4203	HE1	TYR	362	−25.075	19.404	11.815
ATOM	4204	HD1	TYR	362	−27.483	19.377	12.321
ATOM	4205	HH	TYR	362	−23.146	16.562	11.384
ATOM	4206	N	ASN	363	−32.285	17.436	12.334
ATOM	4207	CA	ASN	363	−33.642	16.88	12.392
ATOM	4208	C	ASN	363	−34.145	16.572	10.997
ATOM	4209	O	ASN	363	−34.622	15.476	10.747
ATOM	4210	CB	ASN	363	−34.645	17.862	13.057
ATOM	4211	CG	ASN	363	−36.062	17.337	13.055
ATOM	4212	OD1	ASN	363	−36.261	16.138	12.95
ATOM	4213	ND2	ASN	363	−37.085	18.209	13.181
ATOM	4214	HA	ASN	363	−33.621	15.949	12.982
ATOM	4215	H	ASN	363	−32.091	18.321	12.765
ATOM	4216	HB1	ASN	363	−34.346	18.05	14.099
ATOM	4217	HB2	ASN	363	−34.621	18.817	12.513
ATOM	4218	HD22	ASN	363	−38.023	17.863	13.161
ATOM	4219	HD21	ASN	363	−36.929	19.191	13.289
ATOM	4220	N	ALA	364	−34.051	17.544	10.063
ATOM	4221	CA	ALA	364	−34.586	17.326	8.722
ATOM	4222	C	ALA	364	−33.891	16.159	8.064
ATOM	4223	O	ALA	364	−34.559	15.326	7.474
ATOM	4224	CB	ALA	364	−34.414	18.585	7.833
ATOM	4225	HA	ALA	364	−35.664	17.105	8.808
ATOM	4226	H	ALA	364	−33.616	18.421	10.274
ATOM	4227	HB1	ALA	364	−34.845	18.411	6.834
ATOM	4228	HB2	ALA	364	−34.929	19.442	8.293
ATOM	4229	HB3	ALA	364	−33.348	18.836	7.718
ATOM	4230	N	ALA	365	−32.546	16.076	8.146
ATOM	4231	CA	ALA	365	−31.852	14.953	7.516
ATOM	4232	C	ALA	365	−32.23	13.645	8.175
ATOM	4233	O	ALA	365	−32.398	12.658	7.477
ATOM	4234	CB	ALA	365	−30.319	15.127	7.615
ATOM	4235	HA	ALA	365	−32.122	14.926	6.448
ATOM	4236	H	ALA	365	−32.014	16.767	8.644
ATOM	4237	HB1	ALA	365	−29.801	14.3	7.108
ATOM	4238	HB2	ALA	365	−30.024	16.072	7.136
ATOM	4239	HB3	ALA	365	−30.024	15.142	8.675
ATOM	4240	N	ILE	366	−32.368	13.613	9.52
ATOM	4241	CA	ILE	366	−32.777	12.373	10.185
ATOM	4242	C	ILE	366	−34.14	11.997	9.647
ATOM	4243	O	ILE	366	−34.34	10.864	9.235
ATOM	4244	CB	ILE	366	−32.823	12.528	11.74
ATOM	4245	CG1	ILE	366	−31.387	12.728	12.32
ATOM	4246	CG2	ILE	366	−33.516	11.3	12.4
ATOM	4247	CD1	ILE	366	−31.374	13.326	13.754
ATOM	4248	HA	ILE	366	−32.063	11.572	9.932
ATOM	4249	H	ILE	366	−32.241	14.445	10.065
ATOM	4250	HB	ILE	366	−33.43	13.417	11.973
ATOM	4251	HG11	ILE	366	−30.871	11.76	12.317
ATOM	4252	HG12	ILE	366	−30.797	13.398	11.678
ATOM	4253	HD11	ILE	366	−31.795	12.628	14.491
ATOM	4254	HD12	ILE	366	−30.345	13.56	14.066
ATOM	4255	HD13	ILE	366	−31.953	14.26	13.781
ATOM	4256	HG21	ILE	366	−32.948	10.383	12.183
ATOM	4257	HG22	ILE	366	−33.579	11.424	13.489
ATOM	4258	HG23	ILE	366	−34.544	11.17	12.03
ATOM	4259	N	SER	367	−35.102	12.945	9.649
ATOM	4260	CA	SER	367	−36.443	12.618	9.17
ATOM	4261	C	SER	367	−36.388	12.221	7.709
ATOM	4262	O	SER	367	−37.071	11.286	7.322
ATOM	4263	CB	SER	367	−37.426	13.806	9.35
ATOM	4264	OG	SER	367	−37.668	14.111	10.738
ATOM	4265	HA	SER	367	−36.831	11.767	9.756
ATOM	4266	H	SER	367	−34.903	13.879	9.958
ATOM	4267	HB1	SER	367	−37.053	14.696	8.816
ATOM	4268	HB2	SER	367	−38.401	13.531	8.917
ATOM	4269	HG	SER	367	−36.898	14.422	11.206
ATOM	4270	N	LEU	368	−35.584	12.911	6.87
ATOM	4271	CA	LEU	368	−35.504	12.529	5.46
ATOM	4272	C	LEU	368	−34.986	11.114	5.355
ATOM	4273	O	LEU	368	−35.572	10.327	4.63
ATOM	4274	CB	LEU	368	−34.577	13.476	4.648
ATOM	4275	CG	LEU	368	−34.371	13.067	3.157
ATOM	4276	CD1	LEU	368	−35.705	13.058	2.358
ATOM	4277	CD2	LEU	368	−33.36	14.038	2.482
ATOM	4278	HA	LEU	368	−36.525	12.58	5.05
ATOM	4279	H	LEU	368	−35.031	13.678	7.2
ATOM	4280	HB1	LEU	368	−34.983	14.499	4.701
ATOM	4281	HB2	LEU	368	−33.591	13.477	5.137
ATOM	4282	HG	LEU	368	−33.933	12.055	3.111
ATOM	4283	HD21	LEU	368	−32.398	14.026	3.017
ATOM	4284	HD22	LEU	368	−33.173	13.743	1.438
ATOM	4285	HD23	LEU	368	−33.753	15.066	2.49
ATOM	4286	HD11	LEU	368	−36.21	14.032	2.444
ATOM	4287	HD12	LEU	368	−35.512	12.858	1.293
ATOM	4288	HD13	LEU	368	−36.385	12.274	2.721
ATOM	4289	N	GLY	369	−33.894	10.76	6.07
ATOM	4290	CA	GLY	369	−33.393	9.389	5.989
ATOM	4291	C	GLY	369	−34.505	8.395	6.225
ATOM	4292	O	GLY	369	−34.549	7.379	5.55
ATOM	4293	HA2	GLY	369	−32.619	9.203	6.751
ATOM	4294	HA1	GLY	369	−32.945	9.224	4.996
ATOM	4295	H	GLY	369	−33.419	11.416	6.663
ATOM	4296	N	TYR	370	−35.419	8.667	7.183
ATOM	4297	CA	TYR	370	−36.497	7.713	7.452
ATOM	4298	C	TYR	370	−37.385	7.551	6.233
ATOM	4299	O	TYR	370	−37.885	6.458	6.015
ATOM	4300	CB	TYR	370	−37.362	8.161	8.662
ATOM	4301	CG	TYR	370	−36.631	8.222	10.018
ATOM	4302	CD1	TYR	370	−37.398	8.499	11.156
ATOM	4303	CD2	TYR	370	−35.256	8.005	10.18
ATOM	4304	CE1	TYR	370	−36.821	8.508	12.429
ATOM	4305	CE2	TYR	370	−34.667	8.065	11.447
ATOM	4306	CZ	TYR	370	−35.441	8.33	12.578
ATOM	4307	OH	TYR	370	−34.823	8.415	13.831
ATOM	4308	HA	TYR	370	−36.062	6.725	7.68
ATOM	4309	H	TYR	370	−35.372	9.518	7.715
ATOM	4310	HB2	TYR	370	−37.787	9.154	8.458
ATOM	4311	HB1	TYR	370	−38.199	7.453	8.767
ATOM	4312	HD2	TYR	370	−34.615	7.782	9.338
ATOM	4313	HE2	TYR	370	−33.599	7.902	11.555
ATOM	4314	HE1	TYR	370	−37.455	8.651	13.298
ATOM	4315	HD1	TYR	370	−38.459	8.706	11.054
ATOM	4316	HH	TYR	370	−35.421	8.636	14.535
ATOM	4317	N	ALA	371	−37.593	8.616	5.421
ATOM	4318	CA	ALA	371	−38.404	8.469	4.209
ATOM	4319	C	ALA	371	−37.957	7.274	3.399
ATOM	4320	O	ALA	371	−38.814	6.627	2.818
ATOM	4321	CB	ALA	371	−38.328	9.715	3.288
ATOM	4322	HA	ALA	371	−39.453	8.319	4.512
ATOM	4323	H	ALA	371	−37.192	9.512	5.627
ATOM	4324	HB1	ALA	371	−39.028	9.604	2.444
ATOM	4325	HB2	ALA	371	−38.596	10.624	3.849
ATOM	4326	HB3	ALA	371	−37.313	9.83	2.88
ATOM	4327	N	ASN	372	−36.635	6.976	3.366
ATOM	4328	CA	ASN	372	−36.132	5.78	2.682
ATOM	4329	C	ASN	372	−37.116	4.63	2.713
ATOM	4330	O	ASN	372	−37.372	4.018	1.687
ATOM	4331	CB	ASN	372	−34.817	5.314	3.367
ATOM	4332	CG	ASN	372	−34.245	4.071	2.731
ATOM	4333	OD1	ASN	372	−33.333	4.189	1.928
ATOM	4334	ND2	ASN	372	−34.75	2.866	3.069
ATOM	4335	HA	ASN	372	−35.902	6.031	1.636
ATOM	4336	H	ASN	372	−35.974	7.58	3.82
ATOM	4337	HB1	ASN	372	−34.068	6.118	3.303
ATOM	4338	HB2	ASN	372	−35.002	5.114	4.433
ATOM	4339	HD22	ASN	372	−34.387	2.041	2.643
ATOM	4340	HD21	ASN	372	−35.48	2.766	3.744
ATOM	4341	N	SER	373	−37.676	4.327	3.905
ATOM	4342	CA	SER	373	−38.541	3.152	4.045
ATOM	4343	C	SER	373	−39.811	3.158	3.222
ATOM	4344	O	SER	373	−40.484	2.139	3.225
ATOM	4345	CB	SER	373	−38.892	2.903	5.537
ATOM	4346	OG	SER	373	−39.751	3.928	6.07
ATOM	4347	HA	SER	373	−37.965	2.285	3.688
ATOM	4348	H	SER	373	−37.468	4.884	4.712
ATOM	4349	HB1	SER	373	−39.433	1.951	5.649
ATOM	4350	HB2	SER	373	−37.956	2.83	6.115
ATOM	4351	HG	SER	373	−39.35	4.791	6.074
ATOM	4352	N	CYS	374	−40.178	4.247	2.508
ATOM	4353	CA	CYS	374	−41.358	4.209	1.642
ATOM	4354	C	CYS	374	−41.009	4.572	0.211
ATOM	4355	O	CYS	374	−41.895	5.004	−0.508
ATOM	4356	CB	CYS	374	−42.395	5.183	2.256
ATOM	4357	SG	CYS	374	−44.008	5.021	1.42
ATOM	4358	HA	CYS	374	−41.817	3.208	1.588
ATOM	4359	H	CYS	374	−39.662	5.104	2.55
ATOM	4360	HB1	CYS	374	−42.54	4.951	3.323
ATOM	4361	HB2	CYS	374	−42.018	6.215	2.166
ATOM	4362	HG	CYS	374	−44.402	5.899	1.717
ATOM	4363	LPG1	CYS	374	−43.946	4.981	0.745
ATOM	4364	LPG2	CYS	374	−44.363	4.489	1.646
ATOM	4365	N	LEU	375	−39.741	4.415	−0.241
ATOM	4366	CA	LEU	375	−39.382	4.809	−1.608
ATOM	4367	C	LEU	375	−39.246	3.611	−2.527
ATOM	4368	O	LEU	375	−39.733	3.667	−3.646
ATOM	4369	CB	LEU	375	−38.059	5.626	−1.611
ATOM	4370	CG	LEU	375	−38.042	6.796	−0.58
ATOM	4371	CD1	LEU	375	−36.724	7.612	−0.702
ATOM	4372	CD2	LEU	375	−39.26	7.75	−0.725
ATOM	4373	HA	LEU	375	−40.153	5.456	−2.057
ATOM	4374	H	LEU	375	−39.024	4.038	0.351
ATOM	4375	HB1	LEU	375	−37.224	4.945	−1.378
ATOM	4376	HB2	LEU	375	−37.895	6.026	−2.625
ATOM	4377	HG	LEU	375	−38.076	6.362	0.431
ATOM	4378	HD21	LEU	375	−40.201	7.246	−0.458
ATOM	4379	HD22	LEU	375	−39.148	8.614	−0.053
ATOM	4380	HD23	LEU	375	−39.335	8.119	−1.76
ATOM	4381	HD11	LEU	375	−36.717	8.173	−1.648
ATOM	4382	HD12	LEU	375	−36.637	8.331	0.128
ATOM	4383	HD13	LEU	375	−35.844	6.952	−0.681
ATOM	4384	N	ASN	376	−38.584	2.509	−2.104
ATOM	4385	CA	ASN	376	−38.366	1.403	−3.035
ATOM	4386	C	ASN	376	−39.666	0.89	−3.623
ATOM	4387	O	ASN	376	−39.682	0.68	−4.827
ATOM	4388	CB	ASN	376	−37.519	0.233	−2.46
ATOM	4389	CG	ASN	376	−36.294	0.784	−1.769
ATOM	4390	OD1	ASN	376	−35.418	1.273	−2.464
ATOM	4391	ND2	ASN	376	−36.189	0.741	−0.421
ATOM	4392	HA	ASN	376	−37.771	1.828	−3.863
ATOM	4393	H	ASN	376	−38.196	2.453	−1.184
ATOM	4394	HB1	ASN	376	−38.094	−0.397	−1.769
ATOM	4395	HB2	ASN	376	−37.207	−0.417	−3.294
ATOM	4396	HD22	ASN	376	−35.369	1.12	0.01
ATOM	4397	HD21	ASN	376	−36.896	0.347	0.175
ATOM	4398	N	PRO	377	−40.78	0.677	−2.873
ATOM	4399	CA	PRO	377	−42.013	0.261	−3.53
ATOM	4400	C	PRO	377	−42.438	1.216	−4.62
ATOM	4401	O	PRO	377	−42.905	0.773	−5.657
ATOM	4402	CB	PRO	377	−43.003	0.321	−2.337
ATOM	4403	CG	PRO	377	−42.101	0.051	−1.114
ATOM	4404	CD	PRO	377	−40.834	0.883	−1.428
ATOM	4405	HA	PRO	377	−41.896	−0.766	−3.911
ATOM	4406	HD2	PRO	377	−39.979	0.515	−0.846
ATOM	4407	HD1	PRO	377	−41.013	1.945	−1.197
ATOM	4408	HG2	PRO	377	−41.844	−1.022	−1.095
ATOM	4409	HG1	PRO	377	−42.574	0.326	−0.156
ATOM	4410	HB1	PRO	377	−43.423	1.335	−2.23
ATOM	4411	HB2	PRO	377	−43.84	−0.388	−2.431
ATOM	4412	N	PHE	378	−42.288	2.539	−4.392
ATOM	4413	CA	PHE	378	−42.748	3.508	−5.383
ATOM	4414	C	PHE	378	−41.952	3.358	−6.657
ATOM	4415	O	PHE	378	−42.544	3.289	−7.721
ATOM	4416	CB	PHE	378	−42.611	4.953	−4.835
ATOM	4417	CG	PHE	378	−43.155	5.989	−5.826
ATOM	4418	CD1	PHE	378	−44.527	6.267	−5.864
ATOM	4419	CD2	PHE	378	−42.291	6.676	−6.685
ATOM	4420	CE1	PHE	378	−45.015	7.293	−6.678
ATOM	4421	CE2	PHE	378	−42.775	7.711	−7.491
ATOM	4422	CZ	PHE	378	−44.135	8.035	−7.471
ATOM	4423	HA	PHE	378	−43.813	3.317	−5.598
ATOM	4424	H	PHE	378	−41.854	2.873	−3.552
ATOM	4425	HB1	PHE	378	−43.17	5.038	−3.889
ATOM	4426	HB2	PHE	378	−41.557	5.18	−4.613
ATOM	4427	HD2	PHE	378	−41.238	6.413	−6.728
ATOM	4428	HE2	PHE	378	−42.096	8.263	−8.132
ATOM	4429	HZ	PHE	378	−44.508	8.855	−8.076
ATOM	4430	HE1	PHE	378	−46.078	7.514	−6.694
ATOM	4431	HD1	PHE	378	−45.217	5.69	−5.258
ATOM	4432	N	VAL	379	−40.604	3.302	−6.583
ATOM	4433	CA	VAL	379	−39.83	3.192	−7.82
ATOM	4434	C	VAL	379	−40.18	1.876	−8.484
ATOM	4435	O	VAL	379	−40.449	1.852	−9.677
ATOM	4436	CB	VAL	379	−38.289	3.291	−7.596
ATOM	4437	CG1	VAL	379	−37.531	3.116	−8.944
ATOM	4438	CG2	VAL	379	−37.887	4.654	−6.962
ATOM	4439	HA	VAL	379	−40.13	4.014	−8.492
ATOM	4440	H	VAL	379	−40.14	3.295	−5.694
ATOM	4441	HB	VAL	379	−37.976	2.484	−6.91
ATOM	4442	HG11	VAL	379	−37.877	3.874	−9.662
ATOM	4443	HG12	VAL	379	−36.446	3.243	−8.812
ATOM	4444	HG13	VAL	379	−37.703	2.116	−9.37
ATOM	4445	HG21	VAL	379	−38.362	4.81	−5.983
ATOM	4446	HG22	VAL	379	−36.796	4.691	−6.812
ATOM	4447	HG23	VAL	379	−38.176	5.485	−7.623
ATOM	4448	N	TYR	380	−40.173	0.764	−7.715
ATOM	4449	CA	TYR	380	−40.447	−0.544	−8.312
ATOM	4450	C	TYR	380	−41.803	−0.562	−8.978
ATOM	4451	O	TYR	380	−41.905	−0.973	−10.123
ATOM	4452	CB	TYR	380	−40.401	−1.647	−7.217
ATOM	4453	CG	TYR	380	−40.696	−3.086	−7.684
ATOM	4454	CD1	TYR	380	−40.091	−3.625	−8.826
ATOM	4455	CD2	TYR	380	−41.554	−3.903	−6.934
ATOM	4456	CE1	TYR	380	−40.194	−4.992	−9.108
ATOM	4457	CE2	TYR	380	−41.642	−5.272	−7.203
ATOM	4458	CZ	TYR	380	−40.955	−5.827	−8.285
ATOM	4459	OH	TYR	380	−41.045	−7.201	−8.524
ATOM	4460	HA	TYR	380	−39.668	−0.723	−9.069
ATOM	4461	H	TYR	380	−39.964	0.823	−6.734
ATOM	4462	HB2	TYR	380	−39.392	−1.658	−6.774
ATOM	4463	HB1	TYR	380	−41.105	−1.367	−6.418
ATOM	4464	HD2	TYR	380	−42.146	−3.488	−6.126
ATOM	4465	HE2	TYR	380	−42.244	−5.915	−6.57
ATOM	4466	HE1	TYR	380	−39.671	−5.4	−9.965
ATOM	4467	HD1	TYR	380	−39.514	−3.001	−9.496
ATOM	4468	HH	TYR	380	−40.353	−7.537	−9.089
ATOM	4469	N	ILE	381	−42.863	−0.121	−8.268
ATOM	4470	CA	ILE	381	−44.208	−0.188	−8.839
ATOM	4471	C	ILE	381	−44.322	0.781	−9.99
ATOM	4472	O	ILE	381	−44.859	0.41	−11.021
ATOM	4473	CB	ILE	381	−45.302	0.096	−7.763
ATOM	4474	CG1	ILE	381	−45.334	−1.073	−6.731
ATOM	4475	CG2	ILE	381	−46.698	0.287	−8.427
ATOM	4476	CD1	ILE	381	−46.045	−0.72	−5.397
ATOM	4477	HA	ILE	381	−44.378	−1.203	−9.236
ATOM	4478	H	ILE	381	−42.736	0.276	−7.355
ATOM	4479	HB	ILE	381	−45.046	1.038	−7.249
ATOM	4480	HG11	ILE	381	−45.839	−1.932	−7.199
ATOM	4481	HG12	ILE	381	−44.309	−1.387	−6.475
ATOM	4482	HD11	ILE	381	−47.105	−0.473	−5.548
ATOM	4483	HD12	ILE	381	−45.995	−1.579	−4.709
ATOM	4484	HD13	ILE	381	−45.548	0.137	−4.915
ATOM	4485	HG21	ILE	381	−46.957	−0.601	−9.023
ATOM	4486	HG22	ILE	381	−47.485	0.443	−7.676
ATOM	4487	HG23	ILE	381	−46.705	1.167	−9.089
ATOM	4488	N	VAL	382	−43.847	2.036	−9.858
ATOM	4489	CA	VAL	382	−44.057	2.989	−10.947
ATOM	4490	C	VAL	382	−43.367	2.513	−12.206
ATOM	4491	O	VAL	382	−43.981	2.56	−13.261
ATOM	4492	CB	VAL	382	−43.606	4.43	−10.563
ATOM	4493	CG1	VAL	382	−43.591	5.376	−11.797
ATOM	4494	CG2	VAL	382	−44.556	5.021	−9.483
ATOM	4495	HA	VAL	382	−45.138	3.032	−11.163
ATOM	4496	H	VAL	382	−43.364	2.323	−9.026
ATOM	4497	HB	VAL	382	−42.577	4.383	−10.164
ATOM	4498	HG11	VAL	382	−44.583	5.401	−12.273
ATOM	4499	HG12	VAL	382	−43.322	6.4	−11.493
ATOM	4500	HG13	VAL	382	−42.854	5.045	−12.542
ATOM	4501	HG21	VAL	382	−44.628	4.381	−8.593
ATOM	4502	HG22	VAL	382	−44.182	6.004	−9.171
ATOM	4503	HG23	VAL	382	−45.57	5.152	−9.89
ATOM	4504	N	LEU	383	−42.097	2.057	−12.146
ATOM	4505	CA	LEU	383	−41.395	1.712	−13.385
ATOM	4506	C	LEU	383	−41.633	0.281	−13.829
ATOM	4507	O	LEU	383	−41.836	0.063	−15.015
ATOM	4508	CB	LEU	383	−39.867	1.963	−13.239
ATOM	4509	CG	LEU	383	−39.481	3.434	−12.881
ATOM	4510	CD1	LEU	383	−37.945	3.548	−12.659
ATOM	4511	CD2	LEU	383	−39.9	4.453	−13.98
ATOM	4512	HA	LEU	383	−41.749	2.346	−14.213
ATOM	4513	H	LEU	383	−41.626	1.961	−11.263
ATOM	4514	HB1	LEU	383	−39.496	1.289	−12.45
ATOM	4515	HB2	LEU	383	−39.375	1.687	−14.186
ATOM	4516	HG	LEU	383	−39.978	3.715	−11.936
ATOM	4517	HD21	LEU	383	−40.991	4.526	−14.08
ATOM	4518	HD22	LEU	383	−39.527	5.458	−13.729
ATOM	4519	HD23	LEU	383	−39.477	4.16	−14.954
ATOM	4520	HD11	LEU	383	−37.404	3.362	−13.599
ATOM	4521	HD12	LEU	383	−37.677	4.555	−12.302
ATOM	4522	HD13	LEU	383	−37.605	2.82	−11.908
ATOM	4523	N	CYS	384	−41.594	−0.732	−12.935
ATOM	4524	CA	CYS	384	−41.614	−2.117	−13.416
ATOM	4525	C	CYS	384	−43.001	−2.552	−13.854
ATOM	4526	O	CYS	384	−43.678	−3.225	−13.093
ATOM	4527	CB	CYS	384	−40.999	−3.07	−12.357
ATOM	4528	SG	CYS	384	−40.82	−4.739	−13.076
ATOM	4529	HA	CYS	384	−40.943	−2.198	−14.288
ATOM	4530	H	CYS	384	−41.519	−0.557	−11.948
ATOM	4531	HB1	CYS	384	−40	−2.706	−12.066
ATOM	4532	HB2	CYS	384	−41.631	−3.11	−11.459
ATOM	4533	HG	CYS	384	−40.455	−5.218	−12.269
ATOM	4534	LPG1	CYS	384	−41.416	−4.995	−13.277
ATOM	4535	LPG2	CYS	384	−40.383	−4.747	−13.596
ATOM	4536	N	GLU	385	−43.432	−2.192	−15.091
ATOM	4537	CA	GLU	385	−44.742	−2.619	−15.595
ATOM	4538	C	GLU	385	−45.127	−4.016	−15.159
ATOM	4539	O	GLU	385	−46.136	−4.162	−14.491
ATOM	4540	CB	GLU	385	−44.822	−2.658	−17.151
ATOM	4541	CG	GLU	385	−45.185	−1.304	−17.808
ATOM	4542	CD	GLU	385	−45.37	−1.548	−19.283
ATOM	4543	OE1	GLU	385	−46.474	−2.001	−19.684
ATOM	4544	OE2	GLU	385	−44.401	−1.311	−20.052
ATOM	4545	HA	GLU	385	−45.503	−1.922	−15.209
ATOM	4546	H	GLU	385	−42.875	−1.585	−15.664
ATOM	4547	HB1	GLU	385	−43.869	−3.022	−17.566
ATOM	4548	HB2	GLU	385	−45.611	−3.363	−17.461
ATOM	4549	HG1	GLU	385	−46.134	−0.923	−17.404
ATOM	4550	HG2	GLU	385	−44.394	−0.559	−17.627
ATOM	4551	N	THR	386	−44.371	−5.064	−15.557
ATOM	4552	CA	THR	386	−44.827	−6.424	−15.273
ATOM	4553	C	THR	386	−45.144	−6.593	−13.81
ATOM	4554	O	THR	386	−46.14	−7.222	−13.488
ATOM	4555	CB	THR	386	−43.83	−7.526	−15.723
ATOM	4556	OG1	THR	386	−44.44	−8.814	−15.508
ATOM	4557	CG2	THR	386	−42.479	−7.45	−14.968
ATOM	4558	HA	THR	386	−45.756	−6.586	−15.844
ATOM	4559	H	THR	386	−43.539	−4.923	−16.092
ATOM	4560	HB	THR	386	−43.649	−7.391	−16.803
ATOM	4561	HG1	THR	386	−43.902	−9.538	−15.812
ATOM	4562	HG23	THR	386	−42.032	−6.449	−15.034
ATOM	4563	HG21	THR	386	−42.598	−7.727	−13.909
ATOM	4564	HG22	THR	386	−41.781	−8.155	−15.43
ATOM	4565	N	PHE	387	−44.325	−6.035	−12.893
ATOM	4566	CA	PHE	387	−44.639	−6.204	−11.482
ATOM	4567	C	PHE	387	−45.892	−5.423	−11.176
ATOM	4568	O	PHE	387	−46.768	−5.954	−10.514
ATOM	4569	CB	PHE	387	−43.519	−5.745	−10.519
ATOM	4570	CG	PHE	387	−44.061	−5.88	−9.091
ATOM	4571	CD1	PHE	387	−44.321	−4.748	−8.311
ATOM	4572	CD2	PHE	387	−44.324	−7.154	−8.572
ATOM	4573	CE1	PHE	387	−44.855	−4.892	−7.028
ATOM	4574	CE2	PHE	387	−44.956	−7.29	−7.335
ATOM	4575	CZ	PHE	387	−45.177	−6.161	−6.546
ATOM	4576	HA	PHE	387	−44.822	−7.275	−11.303
ATOM	4577	H	PHE	387	−43.548	−5.461	−13.152
ATOM	4578	HB1	PHE	387	−42.618	−6.364	−10.651
ATOM	4579	HB2	PHE	387	−43.256	−4.7	−10.733
ATOM	4580	HD2	PHE	387	−44.044	−8.043	−9.127
ATOM	4581	HE2	PHE	387	−45.272	−8.267	−6.986
ATOM	4582	HZ	PHE	387	−45.593	−6.267	−5.556
ATOM	4583	HE1	PHE	387	−45.02	−4.025	−6.4
ATOM	4584	HD1	PHE	387	−44.109	−3.754	−8.691
ATOM	4585	N	ARG	388	−46.006	−4.163	−11.646
ATOM	4586	CA	ARG	388	−47.235	−3.414	−11.392
ATOM	4587	C	ARG	388	−48.435	−4.167	−11.926
ATOM	4588	O	ARG	388	−49.471	−4.187	−11.281
ATOM	4589	CB	ARG	388	−47.165	−1.997	−12.02
ATOM	4590	CG	ARG	388	−48.47	−1.188	−11.798
ATOM	4591	CD	ARG	388	−48.324	0.306	−12.198
ATOM	4592	NE	ARG	388	−48.046	0.466	−13.634
ATOM	4593	CZ	ARG	388	−46.864	0.711	−14.166
ATOM	4594	NH1	ARG	388	−45.742	0.759	−13.49
ATOM	4595	NH2	ARG	388	−46.794	0.928	−15.46
ATOM	4596	HA	ARG	388	−47.331	−3.294	−10.302
ATOM	4597	H	ARG	388	−45.27	−3.741	−12.185
ATOM	4598	HB1	ARG	388	−46.321	−1.491	−11.534
ATOM	4599	HB2	ARG	388	−46.96	−2.067	−13.099
ATOM	4600	HG1	ARG	388	−49.281	−1.637	−12.396
ATOM	4601	HG2	ARG	388	−48.762	−1.245	−10.736
ATOM	4602	HD1	ARG	388	−49.305	0.776	−12.008
ATOM	4603	HD2	ARG	388	−47.638	0.833	−11.521
ATOM	4604	HE	ARG	388	−48.87	0.435	−14.256
ATOM	4605	HH12	ARG	388	−44.846	0.986	−13.949
ATOM	4606	HH11	ARG	388	−45.703	0.586	−12.483
ATOM	4607	HH22	ARG	388	−45.895	1.14	−15.917
ATOM	4608	HH21	ARG	388	−47.635	0.91	−16.055
ATOM	4609	N	LYS	389	−48.326	−4.804	−13.109
ATOM	4610	CA	LYS	389	−49.458	−5.556	−13.648
ATOM	4611	C	LYS	389	−49.718	−6.76	−12.765
ATOM	4612	O	LYS	389	−50.87	−7.047	−12.477
ATOM	4613	CB	LYS	389	−49.185	−5.966	−15.124
ATOM	4614	CG	LYS	389	−49.164	−4.709	−16.044
ATOM	4615	CD	LYS	389	−48.572	−4.998	−17.452
ATOM	4616	CE	LYS	389	−48.612	−3.72	−18.337
ATOM	4617	NZ	LYS	389	−47.904	−3.896	−19.628
ATOM	4618	HA	LYS	389	−50.354	−4.913	−13.63
ATOM	4619	H	LYS	389	−47.455	−4.799	−13.603
ATOM	4620	HB1	LYS	389	−48.224	−6.5	−15.172
ATOM	4621	HB2	LYS	389	−49.968	−6.656	−15.479
ATOM	4622	HG1	LYS	389	−50.194	−4.329	−16.147
ATOM	4623	HG2	LYS	389	−48.56	−3.914	−15.58
ATOM	4624	HD1	LYS	389	−47.527	−5.329	−17.34
ATOM	4625	HD2	LYS	389	−49.14	−5.807	−17.94
ATOM	4626	HE1	LYS	389	−49.663	−3.446	−18.53
ATOM	4627	HE2	LYS	389	−48.144	−2.884	−17.788
ATOM	4628	HZ1	LYS	389	−48.304	−4.692	−20.241
ATOM	4629	HZ2	LYS	389	−47.86	−2.975	−20.199
ATOM	4630	HZ3	LYS	389	−46.858	−4.138	−19.499
ATOM	4631	N	ARG	390	−48.664	−7.472	−12.307
ATOM	4632	CA	ARG	390	−48.879	−8.571	−11.364
ATOM	4633	C	ARG	390	−49.477	−8.067	−10.069
ATOM	4634	O	ARG	390	−50.291	−8.765	−9.481
ATOM	4635	CB	ARG	390	−47.564	−9.333	−11.043
ATOM	4636	CG	ARG	390	−47.108	−10.194	−12.254
ATOM	4637	CD	ARG	390	−45.809	−10.989	−11.951
ATOM	4638	NE	ARG	390	−45.38	−11.77	−13.117
ATOM	4639	CZ	ARG	390	−44.435	−12.683	−13.076
ATOM	4640	NH1	ARG	390	−43.763	−12.961	−11.986
ATOM	4641	NH2	ARG	390	−44.143	−13.35	−14.168
ATOM	4642	HA	ARG	390	−49.594	−9.278	−11.807
ATOM	4643	H	ARG	390	−47.727	−7.224	−12.567
ATOM	4644	HB1	ARG	390	−46.782	−8.615	−10.758
ATOM	4645	HB2	ARG	390	−47.73	−9.988	−10.175
ATOM	4646	HG1	ARG	390	−47.902	−10.915	−12.513
ATOM	4647	HG2	ARG	390	−46.942	−9.549	−13.129
ATOM	4648	HD1	ARG	390	−45.01	−10.283	−11.668
ATOM	4649	HD2	ARG	390	−46.039	−11.648	−11.098
ATOM	4650	HE	ARG	390	−45.869	−11.595	−14.01
ATOM	4651	HH12	ARG	390	−43.049	−13.7	−11.991
ATOM	4652	HH11	ARG	390	−43.919	−12.461	−11.103
ATOM	4653	HH22	ARG	390	−43.399	−14.069	−14.17
ATOM	4654	HH21	ARG	390	−44.642	−13.176	−15.052
ATOM	4655	N	LEU	391	−49.077	−6.86	−9.612
ATOM	4656	CA	LEU	391	−49.686	−6.279	−8.42
ATOM	4657	C	LEU	391	−51.144	−6.025	−8.709
ATOM	4658	O	LEU	391	−51.977	−6.403	−7.901
ATOM	4659	CB	LEU	391	−48.971	−4.966	−7.987
ATOM	4660	CG	LEU	391	−49.726	−4.124	−6.918
ATOM	4661	CD1	LEU	391	−49.976	−4.928	−5.617
ATOM	4662	CD2	LEU	391	−48.912	−2.841	−6.585
ATOM	4663	HA	LEU	391	−49.603	−7.014	−7.607
ATOM	4664	H	LEU	391	−48.382	−6.333	−10.102
ATOM	4665	HB1	LEU	391	−47.954	−5.212	−7.639
ATOM	4666	HB2	LEU	391	−48.882	−4.322	−8.869
ATOM	4667	HG	LEU	391	−50.703	−3.809	−7.326
ATOM	4668	HD21	LEU	391	−48.738	−2.241	−7.492
ATOM	4669	HD22	LEU	391	−49.453	−2.216	−5.858
ATOM	4670	HD23	LEU	391	−47.936	−3.111	−6.152
ATOM	4671	HD11	LEU	391	−49.013	−5.228	−5.18
ATOM	4672	HD12	LEU	391	−50.525	−4.299	−4.903
ATOM	4673	HD13	LEU	391	−50.58	−5.826	−5.791
ATOM	4674	N	VAL	392	−51.505	−5.406	−9.853
ATOM	4675	CA	VAL	392	−52.926	−5.189	−10.117
ATOM	4676	C	VAL	392	−53.631	−6.532	−10.155
ATOM	4677	O	VAL	392	−54.698	−6.632	−9.572
ATOM	4678	CB	VAL	392	−53.19	−4.32	−11.381
ATOM	4679	CG1	VAL	392	−54.708	−4.279	−11.717
ATOM	4680	CG2	VAL	392	−52.673	−2.866	−11.177
ATOM	4681	HA	VAL	392	−53.339	−4.628	−9.263
ATOM	4682	H	VAL	392	−50.819	−5.122	−10.527
ATOM	4683	HB	VAL	392	−52.644	−4.764	−12.229
ATOM	4684	HG11	VAL	392	−55.27	−3.863	−10.868
ATOM	4685	HG12	VAL	392	−54.89	−3.647	−12.601
ATOM	4686	HG13	VAL	392	−55.101	−5.283	−11.932
ATOM	4687	HG21	VAL	392	−51.606	−2.847	−10.914
ATOM	4688	HG22	VAL	392	−52.804	−2.282	−12.102
ATOM	4689	HG23	VAL	392	−53.231	−2.367	−10.37
ATOM	4690	N	LEU	393	−53.075	−7.589	−10.794
ATOM	4691	CA	LEU	393	−53.712	−8.911	−10.701
ATOM	4692	C	LEU	393	−53.816	−9.364	−9.257
ATOM	4693	O	LEU	393	−54.722	−10.119	−8.94
ATOM	4694	CB	LEU	393	−52.925	−10.027	−11.452
ATOM	4695	CG	LEU	393	−53.066	−10.019	−13.003
ATOM	4696	CD1	LEU	393	−51.96	−10.897	−13.656
ATOM	4697	CD2	LEU	393	−54.455	−10.545	−13.464
ATOM	4698	HA	LEU	393	−54.742	−8.832	−11.082
ATOM	4699	H	LEU	393	−52.209	−7.486	−11.289
ATOM	4700	HB1	LEU	393	−51.869	−9.906	−11.176
ATOM	4701	HB2	LEU	393	−53.242	−11.022	−11.104
ATOM	4702	HG	LEU	393	−52.931	−8.989	−13.363
ATOM	4703	HD21	LEU	393	−55.271	−9.957	−13.031
ATOM	4704	HD22	LEU	393	−54.544	−10.484	−14.56
ATOM	4705	HD23	LEU	393	−54.594	−11.595	−13.163
ATOM	4706	HD11	LEU	393	−52.032	−11.935	−13.298
ATOM	4707	HD12	LEU	393	−52.065	−10.896	−14.752
ATOM	4708	HD13	LEU	393	−50.958	−10.513	−13.415
ATOM	4709	N	SER	394	−52.902	−8.961	−8.348
ATOM	4710	CA	SER	394	−53.068	−9.325	−6.94
ATOM	4711	C	SER	394	−54.137	−8.477	−6.283
ATOM	4712	O	SER	394	−54.874	−9.015	−5.471
ATOM	4713	CB	SER	394	−51.73	−9.193	−6.172
ATOM	4714	OG	SER	394	−50.757	−10.03	−6.826
ATOM	4715	HA	SER	394	−53.364	−10.384	−6.874
ATOM	4716	H	SER	394	−52.124	−8.39	−8.612
ATOM	4717	HB1	SER	394	−51.409	−8.141	−6.176
ATOM	4718	HB2	SER	394	−51.865	−9.502	−5.121
ATOM	4719	HG	SER	394	−49.892	−9.945	−6.436
ATOM	4720	N	VAL	395	−54.238	−7.166	−6.609
ATOM	4721	CA	VAL	395	−55.274	−6.325	−6.003
ATOM	4722	C	VAL	395	−56.628	−6.757	−6.521
ATOM	4723	O	VAL	395	−57.52	−6.991	−5.722
ATOM	4724	CB	VAL	395	−55.072	−4.805	−6.301
ATOM	4725	CG1	VAL	395	−56.276	−3.954	−5.803
ATOM	4726	CG2	VAL	395	−53.761	−4.279	−5.652
ATOM	4727	HA	VAL	395	−55.256	−6.462	−4.909
ATOM	4728	H	VAL	395	−53.629	−6.766	−7.296
ATOM	4729	HB	VAL	395	−55	−4.664	−7.393
ATOM	4730	HG11	VAL	395	−56.428	−4.103	−4.723
ATOM	4731	HG12	VAL	395	−56.09	−2.884	−5.985
ATOM	4732	HG13	VAL	395	−57.204	−4.225	−6.329
ATOM	4733	HG21	VAL	395	−52.894	−4.849	−6.007
ATOM	4734	HG22	VAL	395	−53.599	−3.221	−5.911
ATOM	4735	HG23	VAL	395	−53.81	−4.367	−4.556
ATOM	4736	N	LYS	396	−56.803	−6.85	−7.857
ATOM	4737	CA	LYS	396	−58.077	−7.299	−8.416
ATOM	4738	C	LYS	396	−58.027	−8.813	−8.41
ATOM	4739	O	LYS	396	−57.198	−9.297	−9.162
ATOM	4740	CB	LYS	396	−58.236	−6.79	−9.876
ATOM	4741	CG	LYS	396	−58.377	−5.244	−9.958
ATOM	4742	CD	LYS	396	−58.514	−4.78	−11.435
ATOM	4743	CE	LYS	396	−58.565	−3.233	−11.595
ATOM	4744	NZ	LYS	396	−59.764	−2.612	−10.98
ATOM	4745	HA	LYS	396	−58.92	−6.888	−7.843
ATOM	4746	H	LYS	396	−56.033	−6.696	−8.478
ATOM	4747	HB1	LYS	396	−57.349	−7.09	−10.453
ATOM	4748	HB2	LYS	396	−59.121	−7.265	−10.331
ATOM	4749	HG1	LYS	396	−59.267	−4.944	−9.384
ATOM	4750	HG2	LYS	396	−57.492	−4.771	−9.501
ATOM	4751	HD1	LYS	396	−57.647	−5.157	−12.003
ATOM	4752	HD2	LYS	396	−59.42	−5.225	−11.878
ATOM	4753	HE1	LYS	396	−57.652	−2.791	−11.162
ATOM	4754	HE2	LYS	396	−58.562	−3.006	−12.677
ATOM	4755	HZ1	LYS	396	−59.76	−2.658	−9.9
ATOM	4756	HZ2	LYS	396	−59.834	−1.559	−11.222
ATOM	4757	HZ3	LYS	396	−60.682	−3.07	−11.325
ATOM	4758	N	PRO	397	−58.822	−9.599	−7.635
ATOM	4759	CA	PRO	397	−58.615	−11.045	−7.57
ATOM	4760	C	PRO	397	−58.211	−11.777	−8.833
ATOM	4761	O	PRO	397	−59.055	−12.385	−9.472
ATOM	4762	CB	PRO	397	−60.009	−11.462	−7.041
ATOM	4763	CG	PRO	397	−60.363	−10.323	−6.06
ATOM	4764	CD	PRO	397	−59.901	−9.054	−6.817
ATOM	4765	HA	PRO	397	−57.862	−11.246	−6.79
ATOM	4766	HD2	PRO	397	−59.593	−8.283	−6.096
ATOM	4767	HD1	PRO	397	−60.705	−8.672	−7.467
ATOM	4768	HG2	PRO	397	−59.764	−10.45	−5.142
ATOM	4769	HG1	PRO	397	−61.431	−10.299	−5.787
ATOM	4770	HB1	PRO	397	−60.746	−11.454	−7.861
ATOM	4771	HB2	PRO	397	−60.008	−12.458	−6.568
ATOM	4772	N	ALA	398	−56.909	−11.747	−9.197
ATOM	4773	CA	ALA	398	−56.448	−12.47	−10.38
ATOM	4774	C	ALA	398	−57.235	−12.074	−11.607
ATOM	4775	O	ALA	398	−57.574	−12.936	−12.402
ATOM	4776	CB	ALA	398	−56.462	−13.997	−10.11
ATOM	4777	HA	ALA	398	−55.406	−12.188	−10.603
ATOM	4778	H	ALA	398	−56.245	−11.192	−8.685
ATOM	4779	HB1	ALA	398	−56.024	−14.545	−10.959
ATOM	4780	HB2	ALA	398	−55.875	−14.219	−9.206
ATOM	4781	HB3	ALA	398	−57.491	−14.355	−9.957
ATOM	4782	N	ALA	399	−57.526	−10.765	−11.784
ATOM	4783	CA	ALA	399	−58.278	−10.326	−12.96
ATOM	4784	C	ALA	399	−57.801	−8.958	−13.392
ATOM	4785	O	ALA	399	−57.246	−8.259	−12.562
ATOM	4786	CB	ALA	399	−59.782	−10.285	−12.603
ATOM	4787	HA	ALA	399	−58.117	−11.013	−13.808
ATOM	4788	H	ALA	399	−57.266	−10.072	−11.104
ATOM	4789	HB1	ALA	399	−60.377	−9.955	−13.469
ATOM	4790	HB2	ALA	399	−60.12	−11.287	−12.298
ATOM	4791	HB3	ALA	399	−59.948	−9.587	−11.768
ATOM	4792	N	GLN	400	−57.975	−8.541	−14.667
ATOM	4793	CA	GLN	400	−57.433	−7.246	−15.081
ATOM	4794	C	GLN	400	−58.057	−6.792	−16.38
ATOM	4795	O	GLN	400	−58.449	−7.645	−17.159
ATOM	4796	CB	GLN	400	−55.893	−7.38	−15.241
ATOM	4797	CG	GLN	400	−55.175	−6.023	−15.475
ATOM	4798	CD	GLN	400	−53.675	−6.191	−15.393
ATOM	4799	OE1	GLN	400	−52.992	−6.029	−16.391
ATOM	4800	NE2	GLN	400	−53.125	−6.523	−14.207
ATOM	4801	HA	GLN	400	−57.669	−6.499	−14.305
ATOM	4802	H	GLN	400	−58.425	−9.113	−15.356
ATOM	4803	HB1	GLN	400	−55.496	−7.831	−14.322
ATOM	4804	HB2	GLN	400	−55.669	−8.068	−16.072
ATOM	4805	HG1	GLN	400	−55.449	−5.618	−16.463
ATOM	4806	HG2	GLN	400	−55.477	−5.294	−14.708
ATOM	4807	HE22	GLN	400	−52.138	−6.658	−14.141
ATOM	4808	HE21	GLN	400	−53.681	−6.645	−13.388
ATOM	4809	N	GLY	401	−58.168	−5.471	−16.645
ATOM	4810	CA	GLY	401	−58.754	−5.037	−17.91
ATOM	4811	C	GLY	401	−58.833	−3.534	−17.983
ATOM	4812	O	GLY	401	−58.48	−2.864	−17.026
ATOM	4813	HA2	GLY	401	−59.772	−5.446	−18.012
ATOM	4814	HA1	GLY	401	−58.139	−5.401	−18.748
ATOM	4815	H	GLY	401	−57.859	−4.768	−16
ATOM	4816	H13	GLY	401	−59.204	−3.036	−18.879

The data shown in Table 1 are expressed based on the Protein Data Bank (PDB) format: The PDB format is a format containing coordinates (X, Y, Z), etc. of individual atoms constituting a protein, and is one of the standard formats in handling coordinates of biopolymers. In Table 1, the “ATOM” appearing in the utmost left column (1st column) denotes each atom of the atomic coordinates. The numbers (1, 2, 3, . . . 4816) appearing in the next column (2nd column) are serial numbers of individual atoms. Subsequently, in the left to right direction in this Table, there are denoted the type of each atom and its position in the amino acid to which it belongs (e.g., “CB”, “CG”, “SD”) (in the 3rd column); the amino acid residue to which each atom belongs (three-letter abbreviations for amino acids, e.g. “MET”, “ASN”) (in the 4th column); the sequence number of the residue counted from the N-terminal (in the 5th column); X-coordinate (in angstrom unit) (in the 6th column); Y-coordinate (in angstrom unit) (in the 7th column); Z-coordinate (in angstrom unit)(in the 8th column).

In addition to the above-described atomic coordinates, the present invention also includes derivatives therefrom, i.e., derivatives from the above-mentioned atomic coordinates (related receptors, etc.) obtained by techniques such as homology modeling on computer. The term “derivatives” means proteins of the GPCR family that have 15% or more, preferably 30% or more, homology to native human MCH-R1 in the amino acid sequence; or atomic coordinates (derived coordinates) in which a part of the amino acid sequence of native human MCH-R1 (preferably one or several (e.g., one to ten) amino acids) is deleted, substituted or added and which exhibit a three-dimensional structure of a protein having activity functionally equivalent to native human MCH-R1 (i.e., the signal transduction activity of GPCRs). Further, in the case of a GPCR family protein that is too low in homology to make an alignment of amino acid sequences with human MCH-R1 in all regions, modeling may be performed on the seven helix sites alone that can be determined using hydrophobicity or the like as an indicator. Whether a given set of atomic coordinates constituting a mutated GPCR amino acid sequence is included as a derivative of the present invention can be analyzed by comparing the three-dimensional structure of the GPCR in question and native human MCH-R1 (as represented by Table 1) by using as a parameter the discrepancies between the positions of α carbon atoms of specific amino acid residues.

Specifically, an image of the three-dimensional structure composed of the atomic coordinates of native human MCH-R1 (designated “three-dimensional structure I”) and an image of the three-dimensional structure composed of the derived coordinates in question (designated “three-dimensional structure II”) are created on computer based on the two sets of atomic coordinates. Subsequently, one image is superimposed on the other image on a computer display. The image of three-dimensional structure I contains seven helix sites of human MCH-R1. These regions are superimposed on the regions of the corresponding helix sites in the image of three-dimensional structure II, or vice versa. This superimposition may be processed automatically based on a computer program, or may be carried out manually on a computer display in a manner similar to the one employed in comparing fingerprints. A suitable program includes COMPOSER or MODELER.

The seven helix sites (regions), the three extra-cellular sites (regions), the three intra-cellular sites (regions) and the carboxy terminus of human MCH-R1 include the first helix (expressed as “HI (106-135)”) consisting of an amino acid sequence from position 106 to position 135 (SEQ ID NO: 2) of the amino acid sequence as shown in SEQ ID NO: 1 (hereinafter, all the position numbers mentioned in this paragraph refer to position numbers in SEQ ID NO: 1), the second helix (expressed as “HII (146-175)”) consisting of an amino acid sequence from position 146 to position 175 (SEQ ID NO: 3), the third helix (expressed as “HIII (183-213)”) consisting of an amino acid sequence from position 183 to position 213 (SEQ ID NO: 4), the fourth helix (expressed as “HIV (226-249)”) consisting of an amino acid sequence from position 226 to position 249 (SEQ ID NO: 5), the fifth helix (expressed as “HV (274-302)”) consisting of an amino acid sequence from position 274 to position 302 (SEQ ID NO: 6), the sixth helix (expressed as “HVI (319-350)”) consisting of an amino acid sequence from position 319 to position 350 (SEQ ID NO: 7), the seventh helix (expressed as “HVII (360-383)”) consisting of an amino acid sequence from position 360 to position 383 (SEQ ID NO: 8); the first extra-cellular region (expressed as “ECI (176-182)”) consisting of an amino acid sequence from position 176 to position 182 (SEQ ID NO: 9), the second extra-cellular region (expressed as “ECII (250-273)”) consisting of an amino acid sequence from position 250 to position 273 (SEQ ID NO: 10), the third extra-cellular region (expressed as “ECIII (351-359)”) consisting of an amino acid sequence from position 351 to position 359 (SEQ ID NO: 11), the first intra-cellular region (expressed as “ICI (136-145)”) consisting of an amino acid sequence from position 136 to position 145 (SEQ ID NO: 12), the second intra-cellular region (expressed as “ICII (214-225)”) consisting of an amino acid sequence from position 214 to position 225 (SEQ ID NO: 13), the third intra-cellular region (expressed as “ICIII (303-318)”) consisting of an amino acid sequence from position 303 to position 318 (SEQ ID NO: 14), and the carboxy terminal region (expressed as “CTERM (384-401)”) consisting of an amino acid sequence from position 384 to position 401 (SEQ ID NO: 15). Then, these regions are superimposed on the corresponding regions of the three-dimensional structure II or vice versa, to calculate the discrepancies between the positions of the α carbon atoms in the amino acid residues of those helices in the three-dimensional structure I and the positions of the corresponding α carbon atoms in the amino acid residues of the corresponding helices in the three-dimensional structure II. When the mean residual of the discrepancies is 1.5 Å, preferably 1.0 , more preferably 0.5, or less, the three-dimensional structure II is regarded as a derivative of the atomic coordinates as shown in Table 1 (derived coordinates). Discrepancies between the positions of corresponding α carbon atoms can be calculated by the so-called least squares method. Generally, such discrepancies can be calculated using a computer software (e.g., LSQKAB, Quanta). The mean residual is calculated as follows. Briefly, individual distances between two corresponding α carbon atoms are squared; the mean value of these squares is calculated; and then the square root of the mean value is calculated to obtain the mean residual.

An active site or protein-binding site is formed by at least one helix selected from the above-described seven helices. Accordingly, a G protein-coupled receptor that has a three-dimensional structure of that active site or protein-binding site, preferably at least one helix consists of HIII, HV, HVI and HVII, is also included in the G protein-coupled receptor of the invention.

In addition to the GPCR (human MCH-R1) having the three-dimensional structure consisting of the atomic coordinates as shown in Table 1, the present invention also includes a three-dimensional structure consisting of such derived coordinates as the GPCRs of the invention.

In Table 1, atomic coordinates for the amino acid residues of individual helices and extra-cellular regions corresponds to amino acid residues 106-135 for HI, 146-175 for HII, 176-182 for ECI, 183-213 for HIII, 226-249 for HIV, 250-273 for ECII, 274-302 for HV, 319-350 for HVI, 351-359 for ECIII and 360-383 for HVII (residue numbers are entered in the 5th column).

II. Uses of the 3D Coordinates of MCH-R1

For the first time, the present invention permits the use of virtual design techniques (i.e., computer modeling or “in silico”) to design, select, and synthesize a drug candidate capable of inhibiting/stimulating or binding MCH-R1. In turn, these drug candidates may be effective in the treatment of a MCH-R1 mediated disorder.

The term “MCH-R1 mediated disorder” is a disorder that involves a modulation in MCH-R1 activity in the biological manifestation of the disease, disorder, and/or condition; in the biological cascade leading to the disorder; or as a symptom of the disorder. This “involvement” of MCH-R1 in a MCH-R1 mediated disorder includes, but is not limited to, the following: (1) The modulation of MCH-R1 activity as a “cause” of the disorder or biological manifestation, whether the MCH-R1 is modulated genetically, by infection, by autoimmunity, trauma, biomechanical causes, lifestyle, or by some other causes. (2) The modulated MCH-R1 activity is part of the observable manifestation of the disease or disorder. That is, the disease or disorder is measurable in terms of the modulated MCH-R1 activity. From a clinical standpoint, modulated MCH-R1 activity indicates the disease, however, MCH-R1 activity need not be the “hallmark” of the disease or disorder. (3) The modulated MCH-R1 activity is part of the biochemical or cellular cascade that results in the disease or disorder. In this respect, inhibiting or stimulating of MCH-R1 (per the respective therapeutic goal) interrupts the cascade, and thus controls the disease. “Modulation in MCH-R1 activity,” as used herein, encompasses both unwanted or elevated MCH-R1 activity and desired or reduced MCH-R1 activity.

Non-limiting examples of MCH-R1 mediated disorders that may be treated by agonists or antagonists identified by the present invention include obesity, anorexia, inflammation, mental disorders, cachexia, metabolic and eating disorders, diabetes, insulin resistance, glucose intolerance, Type-2 diabetes mellitus, coronary artery disease, elevated blood pressure, hypertension, dyslipidaeniia, cancer (e.g., endometrial, cervical, ovarian, breast, prostate, gallbladder, colon), menstrual irregularities, hirsutism, infertility, gallbladder disease, restrictive lung disease, sleep apnea, gout, osteoarthritis, and thromboembolic disease, memory (including learning), cardiovascular function, sepsis, cardiogenic and hypovolemic shock, sexual dysfunction, penile erection, muscle atrophy, nerve growth and repair, intrauterine fetal growth, and the like.

In the present invention, it is possible to carry out virtual screening for drugs using the above-described atomic coordinates or derived coordinates therefrom.

Briefly, the atomic coordinates of the three-dimensional structure elucidated by the invention are input into a computer so that images of the structure and various parameters are shown on the display. All the information contained in Table 1 may be input, or atomic coordinates corresponding to at least one helix, or atomic coordinates corresponding to at least one extra-cellular region, or atomic coordinates corresponding to two helices linked by an extra-cellular region, or atomic coordinates corresponding to the top fifteen residues of at least one helix, or atomic coordinates corresponding to the top fifteen residues of two helices linked by an extra-cellular region may be input. For example, atomic coordinates corresponding to HI (106-135), HII (146-175), HIII (183-213), HIV (226-249), HV (274-302), HVI (319-350), HVII (360-383), ECI (176-182), ECII (250-273), ECIII (351-359), THII-ECI-THIII (161-197), THIV-ECII-THV (235-288), THVI-ECIII-THVII (336-374), TH-I (106-120), TH-II (161-175), TH-III (183-197), TH-IV (235-249), TH-V (274-288), TH-VI (336-350), and/or TH-VII (360-374) may be input.

Then, the resultant data are input into a virtual compound library. Since a virtual compound library is contained in a virtual screening software such as DOCK-4 (Kuntz, UCSF), the above-described data may be input into such a software. Candidate drugs may be searched for, using a three-dimensional structure database of virtual or non-virtual drug candidate compounds, such as MDDR (Prous Science, Spain).

The potential stimulating/inhibitory or binding effect (i.e., interaction or association) of a drug candidate compound may be analyzed prior to its actual synthesis and testing by the use of computer modeling techniques. If the theoretical structure of the given compound suggests insufficient interaction and association between it and MCH-R1, synthesis and testing of the candidate is obviated. However, if computer modeling indicates a strong interaction, the molecule may then be synthesized and tested for its ability to bind to or stimulate/inhibit MCH-R1 using various methods known in the art. Examples of such methods include the measurement of second messenger responses, in particular cAMP, such as the use of modified cell systems yielding color reaction upon accumulation of second messenger elements such as cAMP, e.g. as described by Chen et al. 1995 (Anal Biochem. 1995, 226, 349-54), Cytosensor Microphysiometer techniques (see Boyfield et al. 1996). In this manner, synthesis of inoperative candidates may be avoided.

Agonist/antagonist or binding drug candidates of MCH-R1 may be computationally evaluated and designed by means of a series of steps in which chemical entities or fragments are screened and selected for their ability to bind with the individual binding sites (e.g., HI, HV, HVI, HVII, ECI, ECII, ECIII) or other areas of MCH-R1.

One skilled in the art may use one of several methods to screen chemical entities or fragments for their ability to associate with MCH-R1 and more particularly with the individual binding sites. This process may begin by visual inspection of, for example, the active site on the computer screen based on the MCH-R1 coordinates in Table I. Selected fragments or chemical entities may then be positioned in a variety of orientations, or docked, within an individual binding site of MCH-R1 as defined supra. Docking may be accomplished using software such as QUANTA, SYBYL, followed by energy minimization and molecular dynamics with standard molecular mechanics forcefields, such as CHARMM and AMBER.

Specialized computer programs may also assist in the process of selecting fragments or chemical entities. These include: (1) GRID (Goodford, P. J., “A Computational Procedure for Determining Energetically Favorable Binding Sites on Biologically Important Macromolecules” J. Med. Chem., 28, pp. 849-857 (1985)), available from Oxford University, Oxford, UK; (2) MCSS (Miranker, A. and M. Karplus, “Functionality Maps of Binding Sites: A Multiple Copy Simultaneous Search Method.” Proteins: Structure, Function and Genetics, 11, pp. 29-34 (1991)), available from Molecular Simulations, Burlington, Mass; (3) AUTODOCK (Goodsell, D. S. and A. J. Olsen, “Automated Docking of Substrates to Proteins by Simulated Annealing” Proteins: Structure. Function, and Genetics, 8, pp. 195-202 (1990)), available from Scripps Research Institute, La Jolla, Calif.; and (4) DOCK (Kuntz, I. D. et al., “A Geometric Approach to Macromolecule-Ligand Interactions” J. Mol. Biol., 161, pp. 269-288 (1982)), available from University of California, San Francisco, Calif; (5) GLIDE available from Schrodinger Inc.; (6) FlexX available from Tripos Inc; (7) GOLD (Jones et al., J. Mol. Biol., 245, 43-53, 1995) available from the Cambridge Crystallographic Data Centre.

Once suitable chemical entities or fragments have been selected, they can be assembled in silico or synthesized into a single drug candidate. In silico assembly may proceed by visual inspection of the relationship of the fragments to each other on the three-dimensional image displayed on a computer screen in relation to the structure coordinates of MCH-R1. This would be followed by manual model building using software such as QUANTA or SYBYL. Chemical syntheses are by those methods well-known in the art.

Useful programs to aid one of skill in the art in connecting the individual chemical entities or fragments include the following: (1) CAVEAT (Bartlett, P. A. et al, “CAVEAT: A Program to Facilitate the Structure-Derived Design of Biologically Active Molecules”. In Molecular Recognition in Chemical and Biological Problems”, Special Pub., Royal Chem. Soc., 78, pp. 182-196 (1989)), available from the University of California, Berkeley, Calif.; (2) 3D Database systems such as MACCS-3D (MDL Information Systems, San Leandro, Calif.). This area is reviewed in Martin, Y. C., “3D Database Searching in Drug Design”, J. Med. Chem., 35, pp. 2145-2154 (1992)); and (3) HOOK (available from Molecular Simulations, Burlington, Mass.).

Instead of proceeding to build an MCH-R1 agonist or antagonist in a step-wise fashion one fragment or chemical entity at a time as described above, drug candidates useful for the treatment of MCH-R1 mediated disorders may be designed as a whole or “de novo” using either an empty active site or optionally including some portion(s) of a known agonist or antagonist. These methods include the following: (1) LUDI (Bohm, H.-J., “The Computer Program LUDI: A New Method for the De Novo Design of Enzyme Inhibitors”, J. ComR. Aid. Molec. Design, 6, pp. 61-78 (1992)), available from Biosym Technologies, San Diego, Calif.; (2) LEGEND (Nishibata, Y. and A. Itai, Tetrahedron, 47, p. 8985 (1991)), available from Molecular Simulations, Burlington, Mass.; (3) LeapFrog (available from Tripos Associates, St. Louis, Mo.).

Once a drug candidate has been designed or selected by the above methods, the efficiency with which that candidate may bind to MCH-R1 may be tested and optimized by computational evaluation. An effective MCH-R1 agonist must preferably demonstrate a relatively small difference in energy between its bound and free states (i.e., a small deformation energy of binding). Thus, the most efficient MCH-R1 agonist should preferably be designed with a deformation energy of binding of not greater than about 10 kcal/mole, preferably, not greater than 7 kcal/mole. MCH-R1 agonists may interact with the enzyme in more than one conformation that is similar in overall binding energy. In those cases, the deformation energy of binding is taken to be the difference between the energy of the free compound and the average energy of the conformations observed when the agonist binds to the enzyme.

A compound designed or selected as binding to MCH-R1 may be further computationally optimized so that in its bound state it would preferably lack repulsive electrostatic interaction with the target enzyme. Such non-complementary (e.g., electrostatic) interactions include repulsive charge-charge, dipole-dipole and charge-dipole interactions. Specifically, the sum of all electrostatic interactions between the compound and the enzyme when the compound is bound to MCH-R1, preferably make a neutral or favorable contribution to the enthalpy of binding.

Specific computer software is available in the art to evaluate compound deformation energy and electrostatic interaction. Examples of programs designed for such uses include: Gaussian 92, revision C [M. J. Frisch, Gaussian, Inc., Pittsburgh, Pa. ©1992]; AMBER, version 4.0 [P. A. Kollman, University of California at San Francisco, ©1994]; QUANTA/CHARMM [Molecular Simulations, Inc., Burlington, Mass. ©1994]; and Insight II/Discover (Biosysm Technologies Inc., San Diego, Calif. ©1994). Other software packages will be known to those skilled in the art.

Once a MCH-R1-binding compound has been optimally selected or designed, as described above, substitutions may then be made in some of its atoms or side groups in order to improve or modify its binding properties. Generally, initial substitutions are conservative, i.e., the replacement group will have approximately the same size, shape, hydrophobicity and charge as the original group. It should, of course, be understood that components known in the art to alter conformation should be avoided. Such substituted chemical compounds may then be analyzed for efficiency of fit to MCH-R1 by the same computer methods described in detail, above.

Except as otherwise noted, all amounts including quantities, percentages, portions, and proportions, are understood to be modified by the word “about”, and amounts are not intended to indicate significant digits.

Except as otherwise noted, the articles “a”, “an”, and “the” mean “one or more”.

All documents cited are, in relevant part, incorporated herein by reference; the citation of any document is not to be construed as an admission that it is prior art with respect to the present invention.

While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope.

Claims

1. A method of identifying a drug candidate useful for the treatment of a melanin concentrating hormone receptor 1 (MCH-R1) mediated disorder comprising the steps of: (a) using a three-dimensional (3D) structure of MCH-R1 according to Table 1; (b) employing said 3D structure to design or select in silico said drug candidate.

2. The method according to claim 1, further comprising the step of synthesizing said drug candidate.

3. The method according to claim 2, further comprising contacting said drug candidate in the presence of a substrate to test the ability of said candidate to modulate MCH-R1.

4. The method according to claim 3, wherein said candidate is selected from a database of virtual or non-virtual compounds.

5. The method according to claim 3, wherein said candidate is designed de novo.

6. The method according to claim 3, wherein said candidate is designed from a known agonist or antagonist.

7. The method according to claim 1, wherein said step of employing said 3D structure to design or select said candidate comprises the steps of: (a) identifying in silico chemical entities or fragments capable of binding with a peptide selected from the group consisting of SEQ ID NOS: 2-11; and (b) assembling in silico or synthesizing the identified chemical entities or fragments in into a single molecule to provide the structure of said candidate.

8. The method according to claim 1, wherein said step of employing said 3D structure to design or select said candidate comprises the steps of: (a) identifying in silico chemical entities or fragments capable of binding with a peptide selected from the group consisting of SEQ ID NOS: 16-19; and (b) assembling in silico or synthesizing the identified chemical entities or fragments into a single molecule to provide the structure of said candidate.

9. The method according to claim 1, wherein said step of employing said 3D structure to design or select said candidate comprises the steps of: (a) identifying in silico chemical entities or fragments capable of binding with a peptide selected from the group consisting of SEQ ID NOS: 16, 20-25; and (b) assembling in silico or synthesizing the identified chemical entities or fragments into a single molecule to provide the structure of said candidate.

10. The method according to claim 1, wherein the candidate is an agonist or an antagonist of MCH-R1.

11. A G-protein-coupled receptor selected from the group consisting of the following (a) or (b): (a) a G protein-coupled receptor having three-dimensional structure I defined by the atomic coordinates as shown in Table 1; (b) a G protein-coupled receptor having three-dimensional structure II defined by derived coordinates from the atomic coordinates as shown in Table 1, wherein the mean residual of the discrepancies between the positions of the α carbon atoms in the amino acid residues of seven helix sites SEQ ID NOS: 2-8 of the three-dimensional structure I and the positions of the corresponding α carbon atoms in the amino acid residues of the corresponding seven helix sites of the three-dimensional structure II is 1.5 Å or less when an image of the three-dimensional structure I obtained by computer-processing the atomic coordinates of Table 1 and an image of the three-dimensional structure II obtained by computer-processing said derived coordinates are superimposed.

12. The receptor of claim 11, wherein the G protein-coupled receptor is MCH-R1.

13. The receptor of claim 11, wherein the G protein-coupled receptor is human MCH-R1.

14. A method of identifying a drug candidate useful for the treatment of a melanin concentrating hormone receptor 1 (MCH-R1) mediated disorder comprising the steps of: (a) using a three-dimensional (3D) structure of a G-protein-coupled receptor selected from the group consisting of the following (i) or (ii): (i) a G protein-coupled receptor having three-dimensional structure I defined by the atomic coordinates as shown in Table 1; (ii) a G protein-coupled receptor having three-dimensional structure II defined by derived coordinates from the atomic coordinates as shown in Table 1, wherein the mean residual of the discrepancies between the positions of the α carbon atoms in the amino acid residues of seven helix sites SEQ ID NOS: 2-8 of the three-dimensional structure I and the positions of the corresponding α carbon atoms in the amino acid residues of the corresponding seven helix sites of the three-dimensional structure II is 1.5 Å or less when an image of the three-dimensional structure I obtained by computer-processing the atomic coordinates of Table 1 and an image of the three-dimensional structure II obtained by computer-processing said derived coordinates are superimposed. (b) employing said 3D structure to design or select said drug candidate.

15. The method according to claim 14, further comprising the step of synthesizing said drug candidate.

16. The method according to claim 15, further comprising contacting said drug candidate in the presence of a substrate to test the ability of said candidate to modulate MCH-R1.

17. The method according to claim 16, wherein said candidate is selected from a database of virtual or non-virtual compounds.

18. The method according to claim 16, wherein said candidate is designed de novo.

19. The method according to claim 16, wherein said candidate is designed from a known agonist or antagonist.