Three-dimensional structure of c-Abl

Abstract

The present invention concerns c-Abl, in particular, the three-dimensional structure of c-Abl containing an active DFG conformation. The atomic coordinates of c-Abl possessing this active DFG motif complexed with a specific ligand are also provided.

Description

FIELD OF THE INVENTION

The present invention relates to a recombinant form of c-Abl, in particular, the three-dimensional structure of this protein in a catalytically active conformation. The invention further relates to the use of the three-dimensional structure of c-Abl disclosed herein for identifying and designing ligands or low molecular weight compounds which inhibit the tyrosine kinase activity of c-Abl.

BACKGROUND OF THE INVENTION

Human c-Abl is a structurally complex 145 kDa protein possessing three SRC homology domains (SH1-SH3), located towards the amino terminus. The tyrosine kinase activity of c-Abl is normally tightly regulated by the phosphorylation/de-phosphorylation of residues Tyr245, Tyr412 and Ser465 (isoform B) or Tyr226, Tyr393 and Ser446 (isoform A), together with a number of inter- and intra-molecular interactions. A recent structure of c-Abl in the assembled inactive state shows that critical interactions between the SH2 domain and the kinase domain depend upon a conformational change induced by the binding of myristate within the C-terminal lobe of the kinase domain. See Nagar et al., Cell, Vol. 112, pp. 859-871 (2003).

Kinases can adopt distinct conformations, in which there are large variations in the size and shape of the ATP pocket. See Huse and Kuriyan, Cell, Vol. 109, pp. 275-282 (2002). The crystal structure of STI571 (GLEEVEC) in complex with Abl kinase reveals that the drug targets an inactive conformation of the kinase. In addition to occupying the adenosine sub-site of the ATP pocket, and due to the small size of Thr315, the inhibitor is able to reach past this residue which contributes to the shape of the hydrophobic pocket used to design selectivity into kinase inhibitors, and occupy the space left by the conformational change of the DFG motif. This change is required for the tight binding of STI571. A negative aspect of this type of binding is that inhibitors, such as STI571 are exposed to residues that are neither involved in binding ATP, nor necessary for the function of the enzyme. These residues can be mutated to give changes in structure that prevent STI571 binding without losing enzyme activity, leading to resistance. Thus, in the case of the treatment of advanced chronic myelogenous leukemia (accelerated or blast crisis phase) or of acute lymphoblastic leukemia, patients frequently develop resistance to STI571 therapy and relapse after initially responding to treatment. In the majority of relapsed patients, resistance is the result of point mutations in the Abl kinase domain of the Bcr-Abl protein. These mutant forms of Bcr-Abl are desensitized towards inhibition by STI571, allowing clonal expansion of Ph+cells resistant to the drug. Following the initial findings of Gorre et al. who first isolated the Thr315Ile mutant [see Gorre et al., Science, Vol. 293, pp. 876-880 (2001), studies in which the Bcr-Abl kinase domains from STI571-resistant patients were sequenced revealed more than 30 distinct mutations. Cells are able to generate these mutant forms of Bcr-Abl, since the point mutations in the Abl tyrosine kinase domain do not impede the binding of ATP to the catalytically active conformation of the enzyme, nor hinder the catalytic activity of the active conformation. However, in the case of a drug molecule which binds to the catalytically active ATP-binding conformation to inhibit the kinase, there would be far less scope for drug-resistant, functionally competent mutant forms of the enzyme to undergo clonal expansion, leading to disease progression.

The crystal structure of a complex between PD173955, an inhibitor of Abl kinase, and the kinase domain of Abl has been published and reveals that the ligand binds within the adenine-binding site via two H-bonds and a range of van der Waals interactions. See Nagar et al., Cancer Res, Vol. 62, pp. 4236-4243 (2002). Although this complex has a structure that resembles the catalytically active conformation of other kinases, the DFG motif is in an inactive conformation unsuitable for optimal binding of ATP. See Cowan-Jacob et al., Mini Rev Med Chem, Vol. 4, pp. 285-299 (2004).

It is therefore clear that additional information regarding the conformation of active and inactive forms of c-Abl is necessary to gain a better understanding of this tyrosine kinase and to find ways to inhibit its function when associated with debilitating disease states. To that end, the present invention describes for the first time to our knowledge the three dimensional structure of recombinant human c-Abl possessing a DFG motif in an active conformation determined by crystallization of c-Abl and it is demonstrated herein that this structural information may be used for identifying and/or designing inhibitors of c-Abl with therapeutic usefulness.

SUMMARY OF THE INVENTION

The present invention provides the three-dimensional structure of c-Abl comprising a DFG motif in an active conformation thereby enabling the identification and design of ligands or low molecular weight molecules which may bind to c-Abl, particularly inhibitors of c-Abl.

In one aspect of the invention, a crystal of c-Abl comprising a unit cell with dimensions of a=182.6 Å, b=58.3 Å, c=104.0 Å, beta=119.2 o, with space group C2 is provided.

In another aspect of the invention, a three-dimensional structure of c-Abl comprising the atomic structure coordinates of Table 6 is provided.

In yet another aspect, a crystal of c-Abl comprising an active conformation of the DFG motif is provided.

In a further aspect of the invention, a crystal of c-Abl in which at least one ligand or low molecular weight compound is bound to c-Abl is provided.

In yet another aspect of the invention, a computer readable medium comprising data storage material encoded with computer readable data wherein said data comprises the atomic coordinates of c-Abl as disclosed in Table 6 is provided.

In another aspect, the invention provides a method of determining the three-dimensional structure of c-Abl comprising:

• • (a) crystallisation of c-Abl, the amino acid sequence of which comprises SEQ ID NO. 4, or a mutant, fragment or homologue thereof; and
  • (b) utilizing the atomic coordinates disclosed in Table 6 in whole or in part to determine the three-dimensional structure of said polypeptide.

In a further aspect, the invention provides a method of determining the three-dimensional structure of a complex comprising c-Abl, the amino acid sequence of which comprises SEQ ID NO. 4, or a mutant, fragment or homologue thereof, bound to at least one ligand comprising:

• • (a) obtaining x-ray diffraction data for crystals of the complex; and
  • (b) utilizing the atomic coordinates disclosed in Table 6 in whole or in part to define the three-dimensional structure of the complex.

In another aspect, the invention provides a method of identifying a ligand or low molecular weight compound that binds to c-Abl comprising:

• • (a) utilizing the three dimensional structure of c-Abl derived in whole or in part from the set of atomic coordinates in Table 6 to identify a potential ligand or low molecular weight compound that binds to c-Abl; and
  • (b) selecting those ligands or low molecular weight compounds that bind to c-Abl.

In another aspect of the invention, a method of identifying a ligand or low molecular weight compound that selectively binds to c-Abl is provided comprising:

• • (a) utilizing the three dimensional structure of c-Abl derived in whole or in part from the set of atomic coordinates in Table 6 to identify a potential ligand or low molecular weight compound that binds selectively to c-Abl and to no other tyrosine kinase; and
  • (b) selecting only those ligands or low molecular weight compounds which bind selectively to c-Abl and to no other tyrosine kinase.

In another aspect of the invention, a method of designing a ligand or low molecular weight compound capable of binding to c-Abl is provided comprising:

• • (a) using the atomic coordinates of Table 6 in whole or in part to determine the three dimensional structure of c-Abl;
  • (b) screening said c-Abl with candidate ligands or low molecular weight compounds to determine which bind to c-Abl;
  • (c) selecting those ligands or low molecular weight compounds which bind to c-Abl; and
  • (d) modifying those ligands or low molecular weight compounds which bind to maximize physical properties, such as solubility, affinity, specificity or potency.

In another aspect of the invention, a method of designing a ligand or low molecular weight compound capable of binding selectively to c-Abl is provided comprising:

• • (a) using the atomic coordinates disclosed in Table 6 in whole or in part to determine the three dimensional structure of c-Abl;
  • (b) screening said c-Abl with candidate ligands or low molecular weight compounds to determine which selectively bind to c-Abl and;
  • (c) selecting those ligands or low molecular weight compounds which selectively bind to c-Abl; and
  • (d) modifying those ligands or low molecular weight compounds which bind to maximize physical properties, such as solubility, affinity, specificity or potency.

In preferred embodiments of this invention, the candidate ligands or low molecular weight compounds are screened and designed in silico.

DETAILED DESCRIPTION OF THE INVENTION

The term “unit cell”, according to the invention, refers to the basic shape block. The entire volume of a crystal is constructed by regular assembly of such blocks. Each unit cell comprises a complete representation of the unit of pattern, the repetition of which builds up the crystal.

The term “space group”, according to the invention, refers to the arrangement of symmetry elements of a crystal.

The term “ligand”, according to the invention, refers to a molecule or group of molecules that bind to one or more specific sites of c-Abl. Preferred are ligands that selectively bind to the active site of c-Abl. Ligands according to the invention are preferably low molecular weight molecules.

The term “low molecular weight compound” or “low molecular weight molecules”, according to the invention, refers to preferably organic compounds generally having a molecular weight less than about 1000, more preferably less than about 600. Most preferably, said low molecular weight compounds or ligands selectively inhibit the biological activity of c-Abl.

The term “selective binding” refers to the ability of a ligand or low molecular weight compound to bind to c-Abl but not to any other tyrosine kinase.

The term “in silico” or an “in silico screen”, as used herein, refers to computational or computer methodologies and modeling to predict, e.g., protein function or protein-protein, protein-ligand interaction.

The “DFG motif”, as referred to herein, relates to a stretch of amino acids on the c-Abl protein, e.g., the human form of c-Abl as disclosed in Swiss Prot Accession No. P00519, Isoform 1A) (SEQ ID NO. 1) from amino acids 381-383 that is highly-conserved among protein kinases. The aspartate group (D) from this motif is necessary for the function of the protein because it is involved in positioning magnesium ions and the phosphate groups of ATP correctly for catalysis. An “active DFG motif conformation” refers to the state in which the Phe residue of the motif is buried in a hydrophobic pocket in the groove between the N-terminal, e.g., residues Met290 and Ile293; and C-terminal lobes, e.g., residues His362 and Ala380, of the kinase. See Yamaguchi and Hendrickson, Nature, Vol. 384, pp. 484-489 (1996). This is in contrast to an inactive conformation where the Phe residue, and or other residues, such as the Asp are flipped out in the case of Phe382 [see Schindler et al., Science, Vol. 289, pp. 1938-1942 (2000)] or in the case of Asp [see Nagar et al. (2002), supra] and are therefore not correctly positioned for catalysis. An “optimum active DFG conformation” refers to an active DFG motif conformation with all residues, including those of this motif and the neighboring residues, e.g., Lys271, Glu286, Asp381, Asp363 and Asn368, in a conformation suitable for catalysis.

The terms “active” and “inactive” with regard to the conformation of the c-Abl protein refer to the conformation of the protein which has the DFG motif in the correct conformation for catalytic activity, the activation loop in an extended conformation such that main chain atoms do not traverse the substrate binding site, and Lys-271 and Glu-286 close enough within experimental error to form a salt bridge in the active site (“active”), whereas the inactive conformation can have any one or more of these components in a different conformation that is not suitable for activity (“inactive”). A “catalytically active conformation” refers to a conformational state of the c-Abl protein that is theoretically suitable for performing the kinase reaction based on similarity to structures of other kinases in the active state, e.g., the LCK kinase structure. See Yamaguchi and Hendrickson (1996), supra.

The term “activation loop” refers to a stretch of amino acid residues that starts from the DFG motif and finishes at residue Phe-401 in Abl kinase (SEQ ID NO. 1). In tyrosine kinases this region usually contains one or more tyrosines (Tyr-393 in Abl), that is or are phosphorylated for the kinase to achieve full catalytic activity.

While the sequence of the wild type form of human c-Abl as provided in Swiss Prot Accession No. P00519, Isoform 1A is utilized herein, it is contemplated that other forms and variants of c-Abl may be employed in the instant invention by one of skill in the art without undue experimentation.

In context of a c-Abl inhibitor, the terms “peptide” or “peptide derivative” are intended to embrace a “peptidomimetic” or “peptide analogue” which complement the three-dimensional structure of the binding site of c-Abl or can be designed with improved physical or chemical properties to bind with the three-dimensional binding site of the c-Abl as provided in the present invention.

The term “mutant” refers to possible differences within the wild-type sequence of c-Abl and/or the kinase domain sequence set forth in SEQ ID NO. 4 by deletion, insertion, extension or replacement of one or more selected amino acids.

According to the present invention, the term “mutant” also refers to a polypeptide, whose amino acid sequence differs from the wild type sequence or the kinase domain sequence given in SEQ ID NO.4 by deletion, insertion, extension or preferably replacement of one or more selected amino acids. For example, a c-Abl mutant of the present invention is preferably at least 50% homologous to the wild type sequence, more preferably at least 80% homologous to the wild type sequence, most preferably at least 90% homologous to the wild type sequence.

An “N-terminal extension” of c-Abl, according to the invention, comprises the addition of amino acids at the N-terminus of the full-length c-Abl or a fragment thereof. For example, such N-terminal extension may include the addition of amino acids comprising a stretch of histidine residues that may be utilized to facilitate purification of the protein and which is later cleaved from the protein sequence.

c-Abl may be crystallizable with or without at least one ligand. According to the present invention, c-Abl crystals are stable if kept under suitable conditions. For example, the crystals are stable in their mother liquor at 4° C. for at least 3-4 weeks. Preferably, the crystals are cryo-cooled and stored in liquid nitrogen.

According to the invention, c-Abl may be prepared by methods well-known to one of skill in the art including, but not limited to, isolation from natural sources, e.g., cultured human cells or preferably by recombinant heterologous expression. Expression of recombinant c-Abl is achievable in eukaryotic or prokaryotic systems. For example, recombinant human c-Abl may be expressed in bacteria or Sf9 cells, e.g., as a Strep-tag fusion protein, a glutathione-S-transferase (GST) fusion protein, a histidine-tagged fusion protein or as an untagged protein. If desired, the fusion partner is removed before crystallization. The heterologously produced c-Abl to be used for crystallization is potentially biologically active. Such activity may be determined by morphological, biochemical or viability analysis well-known in the art.

Methods for the preparation of c-Abl mutants are commonly-known in the art. For example, c-Abl mutants may be prepared by expression of c-Abl DNA previously modified in its coding region by oligo-nucleotide directed mutagenesis.

In the present invention, purified c-Abl is preferably at least 90% homogeneous. Protein homogeneity is determinable according to analytical methods well-known in the art, e.g., sequence analysis, electrophoresis, spectroscopic or chromatographic techniques. The purified protein is potentially enzymatically active. Appropriate assays for determining c-Abl activity towards a suitable substrate, e.g., a natural substrate or a synthetic substrate, are known in the art. In one embodiment of the invention, at any step prior to crystallization c-Abl may be complexed with a low molecular weight compound or ligand which is capable of suitably binding to c-Abl. Preferred is a compound inhibiting c-Abl activity. Kinase inhibition is determinable employing assays known in the art. Suitable inhibitors include kinase inhibitors which act on the catalytic site to inhibit c-Abl activity.

Various methods of crystallization familiar to one of skill in the art can be used in the claimed invention including vapor diffusion, dialysis or batch crystallization. In vapor diffusion crystallization, a small volume, i.e., a few microliters, of protein solution is mixed with a solution containing a precipitant. This mixed volume is suspended over a well containing a small amount, i.e., about 0.15-1 mL, of precipitant. Vapor diffusion between the drop and the well will result in crystal formation in the drop.

The dialysis method of crystallization utilizes a semipermeable, size-exclusion membrane that retains the protein but allows small molecules, i.e., buffers and precipitants, to diffuse in and out. In dialysis, rather than concentrating the protein and the precipitant by evaporation, the precipitant is allowed to slowly diffuse through the membrane and reduce the solubility of the protein while keeping the protein concentration fixed.

The batch method generally involves the slow addition of a precipitant to an aqueous solution of protein until the solution just becomes turbid, at this point the container can be sealed and left undisturbed for a period of time until crystallization occurs. In the batch technique the precipitant and the target molecule solution are simply mixed. Supersaturation is achieved directly rather than by diffusion. Often the batch technique is performed under oil. The oil prevents evaporation and extremely small drops can be used. For this, the term “microbatch” is used. A modification of this technique is not to use paraffin oil (which prevents evaporation completely) but rather use silicone oil or a mixture of silicone and paraffin oils so that a slow evaporation is possible.

The claimed invention can encompass any and all methods of crystallization. One skilled in the art can choose any of such methods and vary the parameters such that the chosen method results in the desired crystals. Crystallization methods are also described in Crystallization of Biological Macromolecules, McPherson, Ed., Cold Spring Harbor Laboratory Press, NY (1999)—ISBN 0-87969-527-7, which is hereby incorporated by reference in its entirety.

One preferred method of crystallization of c-Abl involves mixing a c-Abl solution with a “reservoir buffer”, resulting in a lower concentration of the precipitating agent than necessary for crystal formation. For crystal formation, the concentration of the precipitating agent has to be increased, e.g., by addition of precipitating agent, e.g., by titration, or by allowing the concentration of precipitating agent to balance by diffusion between the crystallization buffer and a reservoir buffer. Under suitable conditions such diffusion of water or volatile precipitating agent occurs along the gradient of precipitating agent, e.g., between the reservoir buffer having a higher concentration of precipitating agent and the crystallization buffer having a lower concentration of precipitating agent. Diffusion may be achieved, e.g., by vapor diffusion techniques allowing diffusion of water in the common gas phase. Known techniques are, e.g., vapor diffusion methods, such as the “hanging drop” or the “sitting drop” method. In the vapor diffusion method a drop of crystallization buffer containing the protein is hanging above or sitting beside a much larger pool of reservoir buffer. Alternatively, the equilibration of the precipitating agent can be achieved through a semi-permeable membrane (dialysis method) that separates the crystallization buffer from the reservoir buffer and prevents dilution of the protein into the reservoir buffer.

Formation of c-Abl crystals can be achieved under various conditions, including the conditions disclosed herein, which are essentially determined based on the following parameters: pH, presence of salts and additives, precipitating agent, protein concentration and temperature. The pH may range, e.g., from about 4.0-10.0.

The present invention also relates to a computer readable medium having stored a model of the c-Abl crystal structure. In a preferred embodiment, said model is built from all or part of X-ray diffraction data using methodologies familiar to one of skill in the art. The atomic coordinates are shown in Table 6 appended hereto.

The present invention provides the structure coordinates of recombinant human c-Abl. The term “structure coordinates” or “atomic coordinates” refers to mathematical coordinates derived from the mathematical equations (Fourier transformation) related to the diffraction pattern obtained on a monochromatic beam of X-rays by the atoms (scattering centers) of a crystal comprising a c-Abl. The diffraction data are used to calculate an electron density map of the repeating unit of the crystal. The electron density maps are used to establish the positions of the individual atoms within the unit cell of the crystal.

Structural coordinates of a crystalline composition of this invention may be stored in a machine-readable form on a machine-readable storage medium, e.g., a computer hard drive, diskette, DAT tape, CD, DVD, etc., for display as a three-dimensional shape or for other uses involving computer-assisted manipulation of, or computation based on, the structural coordinates or the three-dimensional structures they define. For example, data defining the three dimensional structure of a protein of c-Abl, or portions or structurally similar homologues of such proteins, may be stored in a machine-readable storage medium, and may be displayed as a graphical three-dimensional representation of the protein structure, typically using a computer capable of reading the data from said storage medium and programmed with instructions for creating the representation from such data.

According to the present invention, a three-dimensional c-Abl model is obtainable from a crystal of c-Abl polypeptide, the amino acid sequence of which comprises SEQ ID NO. 4, or a mutant, fragment or homologue thereof. Such a model can be built or refined from all or part of the c-Abl structure data of the present invention using the X-ray diffraction coordinates, particularly the atomic structure coordinates of Table 6. Ideally, said models contemplated herein all possess a DFG motif in the active conformation.

The knowledge obtained from the three-dimensional model of c-Abl can be used in various ways. It can be used to identify chemical entities, e.g., small organic and bioorganic molecules, such as peptidomimetics and synthetic organic molecules that bind to c-Abl and preferably block or prevent a c-Abl mediated or associated process or event. Using the three-dimensional structure of c-Abl, the skilled artisan can construct a model of c-Abl. For example, every atom can be depicted as a sphere of the appropriate van der Waals radius, and a detailed surface map of c-Abl can be constructed.

Chemical entities that have a surface that mimics the accessible surface of the catalytic binding site of c-Abl can be constructed by those skilled in the art. By way of example, the skilled artisan can screen three-dimensional structural databases of compounds to identify those compounds that position appropriate functional groups in similar three-dimensional structural arrangement, then build combinatorial chemistry libraries around such chemical entities to identify those with high affinity to the catalytic binding site of c-Abl.

Ligands or small molecular compounds can be identified from screening compound databases or libraries and using a computational means to form a fitting operation to a binding site on c-Abl. The three-dimensional structure of c-Abl as provided in the present invention in whole or in part by the structural coordinates of Table 6, can be used together with various docking programs.

The potential inhibitory or binding effect of a chemical entity on c-Abl may be analyzed prior to its actual synthesis and testing by the use of computer-modeling, or “in silico”, techniques familiar to one of skill in the art. If the theoretical structure of the given chemical entity suggests insufficient interaction and association between it and c-Abl, the need for synthesis and testing of the chemical entity is obviated. However, if computer modeling indicates a strong interaction, the molecule may then be synthesized and tested for its ability to bind to c-Abl. Thus, expensive and time-consuming synthesis of inoperative compounds may be avoided.

An inhibitory or other binding compound of c-Abl may be computationally evaluated and designed by means of a series of steps in which chemical entities or fragments are screened and selected for their ability to associate with the individual binding sites of c-Abl. Thus, one skilled in the art may use one of several methods to screen chemical entities or fragments for their ability to associate with c-Abl. This process may begin by visual inspection of, e.g., the binding site on a computer screen based on the structural coordinates of Table 6 in whole or in part. Selected fragments or chemical entities may then be positioned in a variety of orientations, or “docked,” within the catalytic binding site of c-Abl. Docking may be accomplished using software, such as Quanta and SYBYL, followed by energy minimization and molecular dynamics with standard molecular mechanics force fields, such as CHARMM or AMBER. Specialized computer programs may be of use for selecting interesting fragments or chemical entities. These programs include, e.g., GRID, available from Oxford University, Oxford, UK; 5 MCSS or CATALYST, available from Molecular Simulations, Burlington, Mass.; AUTODOCK, available from Scripps Research Institute, La Jolla, Calif.; DOCK, available from University of California, San Francisco, Calif.; and XSITE, available from University College of London, UK.

Using molecular replacement to exploit a set of coordinates, such as those of Table 6 of the invention, the structure of a crystalline c-Abl or portion thereof can, e.g., be bound to one or more ligands or low molecular weight compounds to form a complex.

The term “molecular replacement” refers to a method that involves generating a preliminary structural model of a crystal whose structural coordinates are unknown, by orienting and positioning a molecule whose structural coordinates are known, e.g., the c-Abl coordinates within the unit cell of the unknown crystal, so as to best account for the observed diffraction pattern of the unknown crystal. Phases can then be calculated from this model, and combined with the observed amplitudes to give an approximated Fourier synthesis of the structure whose coordinates are unknown. This in turn can be subject to any of the several forms of refinement to provide a final accurate structure. Using the structural coordinates provided by this invention, molecular replacement may be used to determine the structural coordinates of a crystalline co complex, unknown ligand, mutant or homolog, or of a different crystalline form of c-Abl. Additionally, the claimed crystal and its coordinates may be used to determine the structural coordinates of a chemical entity that associates with c-Abl.

“Homology modeling” according to the invention involves constructing a model of an unknown structure using structural coordinates of one or more related proteins, protein domains and/or one subdomain. Homology modeling may be conducted by fitting common or homologous portions of the protein or peptide whose three dimensional structure is to be solved to the three-dimensional structure of homologous structural elements. Homology modeling can include rebuilding part or all of a three-dimensional structure by replacement of amino acids or other components by those of the related structure to be solved.

Molecular replacement according to the present invention uses a molecule having a known structure. The three-dimensional structure of c-Abl provided in whole or in part in Table 6 in a machine-readable form on a data-carrier can be used as a starting point to model the structure of an unknown crystalline sample. This technique is based on the principle that two molecules which have similar structures, orientations and positions in the unit cell diffract similarly. Molecular replacement involves positioning the known structure in the unit cell in the same location and orientation as the unknown structure. Once positioned, the atoms of the known structure in the unit cell are used to calculate the structure factors that would result from a hypothetical diffraction experiment. This involves rotating the known structure in the six dimensions (three angular and three spatial dimensions) until alignment of the known structure with the experimental data is achieved. This approximate structure can be fine-tuned to yield a more accurate and often higher resolution structure using various refinement techniques. For instance, the resultant model for the structure defined by the experimental data may be subjected to rigid body refinement in which the model is subjected to limited additional rotation in the six dimensions yielding positioning shifts of under about 5%. The refined model may then be further refined using other known refinement methods. The present invention also enables homologues and mutants of c-Abl and the solving of their crystal structure. Based on the three-dimensional structure of c-Abl as provided in the present invention and using the atomic coordinates of Table 6 in whole or in part, the effects of site-specific mutations can be predicted. More specifically, the structural information provided herein permits the identification of desirable sites for amino acid modification, particularly amino acid mutation resulting in substitutional, insertional or deletional variants. Such variants may be designed to have special properties, particularly properties distinct from wild-type c-Abl, such as altered catalytic activity. Substitutions, deletions and insertions may be combined to arrive at a desired variant. Such variants can be prepared by methods well-known in the art, e.g. starting from wild-type c-Abl or by de novo synthesis.

c-Abl may also crystallize in a form different from the one disclosed herein. The structural information provided, for example, in the wild type sequence (Swiss Prot Accession No. P00519, Isoform A) (SEQ. ID NO. 1), SEQ ID NO. 4 and Table 6 in whole or in part, is also useful for solving the structure of other crystal forms. Furthermore, it may serve to solve the structure of a c-Abl mutant, a c-Abl co-complex or a sufficiently homologous protein.

The c-Abl structural information provided herein is useful for the design of ligands or small molecule compounds which are capable of selectively interacting with c-Abl and thereby specifically modulating the biological activity of c-Abl. In particular, the coordinates disclosed herein reflect catalytically active c-Abl possessing an active DFG motif conformation suitable for optimum binding of ATP. Furthermore, this information can be used to design and prepare c-Abl mutants, e.g., mutants with altered catalytic activity, model the three-dimensional structure and solve the crystal structure of proteins, such as c-Abl homologues, c-Abl mutants or c-Abl co-complexes, involving, e.g., molecular replacement.

Preferred is a method for designing a c-Abl inhibitor which interacts at the active binding site possessing the optimum active DFG conformation. The present invention may also be used to design ligands or low molecular weight compounds which specifically inhibit c-Abl and which specifically do not bind to other tyrosine kinases.

One approach enabled by this invention is the use of the structural coordinates of c-Abl to design chemical entities that bind to or associate with c-Abl and alter the physical properties of the chemical entities in different ways. Thus, properties such as, e.g., solubility, affinity, specificity, potency, on/off rates or other binding characteristics may all be altered and/or maximized. One may design desired chemical entities by probing a c-Abl crystal comprising c-Abl with a library of different entities to determine optimal sites for interaction between candidate chemical entities and c-Abl. For example, high-resolution X-ray diffraction data collected from crystals saturated with solutes allows the determination of where each type of solute molecule adheres. Small molecules that bind tightly to those sites can then be designed and synthesized and tested for the desired activity. Once the desired activity is obtained, the molecule can be further altered to maximize desired properties.

The invention also contemplates computational screening of small-molecule databases or designing of chemical entities that can bind in whole or in part to c-Abl. They may also be used to solve the crystal structure of mutants, co-complexes or the crystalline form of any other molecule homologous to, or capable of associating with, at least a portion of c-Abl. One method that may be employed for this purpose is molecular replacement. An unknown crystal structure, which may be any unknown structure, such as, e.g., another crystal form of c-Abl, a c-Abl mutant or peptide or a co-complex with c-Abl, or any other unknown crystal of a chemical entity that associates with c-Abl that is of interest, may be determined using the whole of part of the structural coordinates set forth in Table 6. This method provides an accurate structural form for the unknown crystal far more quickly and efficiently than attempting to determine such information without the invention herein.

In one preferred embodiment of the invention, candidate ligands are screened in silico. The information obtained can be used to obtain specific inhibitors of c-Abl. For example, an inhibitor which inhibits only c-Abl but not other tyrosine kinases.

In another preferred embodiment of the invention, a method is provided to design ligands which inhibit the activity of c-Abl. In a preferred embodiment, a method is provided to design a selective inhibitor which is specific for only c-Abl and not for other tyrosine kinases.

The design of chemical entities that inhibit c-Abl generally involves consideration of at least two factors. First, the chemical entity must be capable of physically or structurally associating with c-Abl, preferably at the catalytic site of c-Abl. The association may be any physical, structural or chemical association, such as, e.g., covalent or non-covalent binding, or van der Waals, hydrophobic or electrostatic interactions. Second, the chemical entity must be able to assume a conformation that allows it to associate with c-Abl, preferentially at the catalytic site of c-Abl possessing the DFG motif for optimum ATP binding as reflected in the coordinates for c-Abl disclosed herein. Although not all portions of the chemical entity will necessarily participate in the association with c-Abl, those non-participating portions may still influence the overall conformation of the molecule. This in turn may have a significant impact on the desirability of the chemical entity. Such conformational requirements include the overall three-dimensional structure and orientation of the chemical entity in relation to all or a portion of the binding site.

Once a compound has been designed or selected by the above methods, the efficiency with which that compound may bind to c-Abl may be tested and modified for the maximum desired characteristic(s) using computational or experimental evaluation. Various parameters can be maximized depending on the desired result. These include, but are not limited to, specificity, affinity, on/off rates, hydrophobicity, solubility and other characteristics readily identifiable by the skilled artisan.

The present invention also relates to identification of compounds which inhibit c-Abl activity. In particular, said compounds are useful in preventing or treating disorders mediated by c-Abl, or variants thereof, e.g., proliferative diseases, such as CML and GIST in which an aberrant BCR-ABL hybrid is implicated, as well as other nonproliferative diseases familiar to one of skill in the art, including but not limited to, e.g., those in which c-Abl is implicated in the trafficking of pathogens, such as prions or viral proteins, into cell nuclei.

For the above uses, the required dosage will depend on the mode of administration, the particular condition to be treated and the desired effect. In general, satisfactory results are to be obtained systematically at daily dosages from about 0.1 mg/kg to about 100 mg/kg body weight. A daily dosage in a larger mammal, e.g., human, is in the range from about 0.5 mg to about 2,000 mg, conveniently administered, e.g., in divided doses up to 4 times a day or in delayed dosage form. The compounds may be administered by any conventional route, in particular, enterally, e.g., orally, e.g., in the form or tablets or capsules, or parenterally, e.g., in the form of injectable solutions or suspensions; topically, e.g., in the form of lotions, gels, ointments or creams; or in a nasal or a suppository form. Pharmaceutical compositions comprising said compound in free form or in a pharmaceutically acceptable salt form in association with at least one pharmaceutically acceptable carrier or diluent may be manufactured in conventional manner by mixing with a pharmaceutically acceptable carrier or diluent. Unit dosage forms for oral administration contain, e.g., from about 0.1 mg to about 500 mg of active substance. Topical administration is, e.g., to the skin. A further form of topical administration is to the eye. Compounds may be administered in free form or in a pharmaceutically acceptable salt form. Such salts may be prepared in a conventional manner and exhibit the same order of activity as the free compounds.

The present invention enables the use of molecular design techniques, particularly the rational drug design approach, to prepare new or improved chemical entities and compounds, including c-Abl inhibitors capable of irreversibly or reversibly modulating c-Abl activity. Improved entities or compounds means that these entities or compounds are superior to the “original” or parent compound they are derived from with regard to a property relevant to therapeutic use including suitability for in vivo administration, e.g., cellular uptake, solubility, stability against (enzymatic) degradation, binding affinity or specificity and the like. For example, on the basis of the information provided herein it is possible to specially design c-Abl inhibitors which covalently, or preferably non-covalently, bind to c-Abl. Such inhibitors may act in a competitive or uncompetitive manner, bind at or close to the active site of c-Abl or act allosterically.

With regard to the design of c-Abl modulators the following aspects should be considered:

• • (i) if the candidate compound is capable of physically and structurally associating with c-Abl; and/or
  • (ii) if the compound is capable of assuming a conformation allowing it to associate with c-Abl.

Advantageously, computer modeling techniques may be used in the process of assessing these abilities for the modulator as a whole, or a fragment thereof in order to minimize efforts in the synthesis or testing of unsuccessful candidate compounds. To this end specialized computer software may be used and is well-known in the art.

Another design approach is to probe a c-Abl crystal with a variety of different chemical entities to determine optimal sites for interaction between candidate c-Abl inhibitors and the target kinase. Yet another possibility which arises from the present invention is to screen computationally small molecule data bases for chemical entities or compounds that are capable of binding, in whole or in part, to a c-Abl catalytic domain. The quality of fit to the binding site may be judged, e.g., by shape complementarity or by estimated interaction energy. Knowledge of the three-dimensional arrangement of the modifications can then be utilized for the design of new c-Abl ligands or low molecular weight compounds, such as selective inhibitors.

Chemical entities that are capable of associating with c-Abl may inhibit its interaction with naturally-occurring ligands of the protein and may inhibit biological functions mediated by such interaction. Such chemical entities are potential drug candidates. Compounds of the structures selected or designed by any of the foregoing means may be tested for their ability to bind to c-Abl and to inhibit the binding to a natural or non-natural ligand thereof, and/or inhibit a biological function mediated by c-Abl.

The following examples serve to illustrate embodiments of the present invention but should not be construed as a limitation thereof.

In practicing the present invention, many conventional techniques in molecular biology are used. These techniques are well-known and are explained in, e.g., the following texts, the contents of which are hereby incorporated by reference. See Current Protocols in Molecular Biology, Vols. I-III, Ausubel, Ed. (1997); Sambrook et al., Molecular Cloning: A Laboratory Manual, 2^nd Edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y. (1989); DNA Cloning: A Practical Approach, Vols. I and II, Glover, Ed. (1985); Oligonucleotide Synthesis, Gait, Ed. (1984); Nucleic Acid Hybridization, Hames and Higgins, Eds. (1985); Transcription and Translation, Hames and Higgins, Eds. (1984); Animal Cell Culture, Freshney, Ed. (1986); Immobilized Cells and Enzymes, IRL Press (1986); A Practical Guide to Molecular Cloning; the series, Methods in Enzymology, Perbal, Ed., Academic Press, Inc. (1984); Gene Transfer Vectors for Mammalian Cells, Miller and Calos, Eds., Cold Spring Harbor Laboratory (1987); and Methods in Enzymology, Vols. 154 and 155, Wu and Grossman, and Wu, Eds., respectively (1987). In addition, unless noted otherwise, the manufacturer's recommendations are followed when using commercially-available kits.

EXAMPLE 1

Generation of c-Abl for Expression in Insect Cells

The DNA construct comprising the kinase domain of c-Abl is cloned and expressed in the baculovirus/Sf9 system as described in Bhat et al., J Biol Chem, Vol. 27, pp. 16170-16175 (1997). Cell culture and propagation is performed as described therein with minor modifications. Specifically, Sf9 cells are grown in Excell 400 medium (JRH Biosciences) containing 5% (v/v) fetal calf serum (fcs) in Techne spinner bottles at 28° C. with rotation at 80 rpm.

To generate a high titer virus stock, an amplification protocol is applied where stepwise the Sf9 cell amounts and Excell 400 medium volumes, as well as the infecting virus supernatant volumes, are increased until a virus stock of 500 mL is generated.

Expression of recombinant c-Abl protein in Sf9 cells is carried out in a 8 L total volume bioreactor (FairMenTec GmbH, Germany). Cells are seeded at a density of 2×10⁵ cells/mL in Excell 400 medium+5% fcs and grown to a density of 2.5×10⁶ cells/mL in a volume of 5 L. The O₂ level is maintained at 36% saturation by oxygen-sensor (Cole Parmer) driven addition of O₂ as required. The culture is stirred with a pitch-blade impeller at a speed of 125 rpm throughout the culture time. The pH of the culture generally remains constant during this time when Excell 400 medium is used. The culture temperature is maintained at 28° C. by a water-jacket surrounding the culture vessel. Compressed air is added to the headroom to prevent foaming. Recombinant baculovirus harboring the gene encoding a His-tagged fragment (amino acids P218-S500) of human Abl-kinase (Swiss Prot Accession No. P00519; and Isoform IA, see Tables 1 and 2, below) is added to give a multiplicity of infection (m.o.i.) of 10.

TABLE 1
Swiss Prot Accession No. P00519; Isoform IA of Human c-Abl
[SEQ ID NO. 1]
10         20         30         40         50         60
|          |         |         |         |         |
MLEICLKLVG CKSKKGLSSS SSCYLEEALQ RPVASDFEPQ GLSEAARWNS KENLLAGPSE
70         80         90        100        110        120
|          |         |         |         |         |
NDPNLFVALY DFVASGDNTL SITKGEKLRV LGYNHNGEWC EAQTKNGQGW VPSNYITPVN
130        140        150        160        170        180
|          |         |         |         |         |
SLEKHSWYHG PVSRNAAEYL LSSGINGSFL VRESESSPGQ RSISLRYEGR VYHYRINTAS
190        200        210        220        230        240
|          |         |         |         |         |
DGKLYVSSES RFNTLAELVH HHSTVADGLI TTLHYPAPKR NKPTVYGVSP NYDKWEMERT
250        260        270        280        290        300
|          |         |         |         |         |
DITMKHKLGG GQYGEVYEGV WKKYSLTVAV KTLKEDTMEV EEFLKEAAVM KEIKHPNLVQ
310        320        330        340        350        360
|          |         |         |         |         |
LLGVCTREPP FYIITEFMTY GNLLDYLREC NRQEVNAVVL LYMATQTSSA MEYLEKKNFI
370        380        390        400        410        420
|          |         |         |         |         |
HRDLAARNCL VGENHLVKVA DFGLSRLMTG DTYTAHAGAK FPIKWTAPES LAYNKESIKS
430        440        450        460        470        480
|          |         |         |         |         |
DVWAFGVLLW EIATYGMSPY PGIDLSQVYE LLEKDYRMER PEGCPEKVYE LMRACWQWNP
490        500        510        520        530        540
|          |         |         |         |         |
SDRPSFAEIH QAFETMFQES SISDEVEKEL GKQGVRGAVS TLLQAPELPT KTRTSRRAAE
550        560        570        580        590        600
|          |         |         |         |         |
HRDTTDVPEM PHSKGQGESD PLDHEPAVSP LLPRKERGPP EGGLNEDERL LPKDKKTNLF
610        620        630        640        650        660
|          |         |         |         |         |
SALIKKKKKT APTPPKRSSS FRENDGQPER RGAGEEEGRD ISNGALAFTP LDTADPAKSP
670        680        690        700        710        720
|          |         |         |         |         |
KPSNGAGVPN GALRESGGSG FRSPHLWKKS STLTSSRLAT GEEEGGGSSS KRFLRSCSAS
730        740        750        760        770        780
|          |         |         |         |         |
CVPHGAKDTE WRSVTLPRDL QSTGRQFDSS TFGGHKSEKP ALPRKRAGEN RSDQVTRGTV
790        800        810        820        830        840
|          |         |         |         |         |
TPPPRLVKKN EEAADEVFKD IMESSPGSSP PNLTPKPLRR QVTVAPASGL PHKEEAEKGS
850        860        870        880        890        900
|          |         |         |         |         |
ALGTPAAAEP VTPTSKAGSG APGGTSKGPA EESRVRRHKH SSESPGRDKG KLSRLKPAPP
910        920        930        940        950        960
|          |         |         |         |         |
PPPAASAGKA GGKPSQSPSQ EAAGEAVLGA KTKATSLVDA VNSDAAKPSQ PGEGLKKPVL
970        980        990       1000       1010       1020
|          |         |         |         |         |
PATPKPQSAK PSGTPISPAP VPSTLPSASS ALAGDQPSST AFIPLISTRV SLRKTRQPPE
1030       1040       1050       1060       1070       1080
|          |         |         |         |         |
RIASGATTKG VVLDSTEALC LAISRNSEQM ASHSAVLEAG KNLYTFCVSY VDSTQQMRNK
1090       1100       1110       1120       1130
|          |         |         |         |
FAFREAINKL ENNLRELQIC PATAGSGPAA TQDFSKLLSS VKETSDIVQR

The c-Abl polypeptide fragment used in this invention comprises the kinase domain (proline 218 to serine 500) and also comprises an additional stretch of 27 amino acids at the N-terminus comprising a 6×His stretch to allow purification by immobilized metal affinity chromatography (IMAC), as well as a cleavage site for Factor Xa protease digestion (IEGR) to allow removal of the first 23 amino acids prior to the final purification (see SEQ ID NO. 2 and Table 2 below).

[SEQ ID NO 2]
MGYPYDVPDY AMAHHHHHHI EGRAAMD

TABLE 2
c-Abl Kinase Fragment, Amino Acids 218-500
[SEQ ID NO. 3]
Factor Xa                        Papain
↓       218         ↓
MGYPYDVPDY AMAHHHHHHI EGRAAMDPKR NKPTVYGVSP
NYDKWEMERT DITMKHKLGG GQYGEVYEGV WKKYSLTVAV KTLKEDTMEV EEFLKEAAVM
KEIKHPNLVQ LLGVCTREPP FYIITEFMTY GNLLDYLREC NRQEVNAVVL LYMATQISSA
MEYLEKKNFT HRDLAARNCL VGENHLVKVA DFGLSRLMTG DTYTAHAGAK FPIKWTAPES
LAYNKFSIKS DVWAFGVLLW
EIATYGMSPY PGTDLSQVYE LLEKDYRMER PEGCPEKVYE LMRACWQWNP SDRPSFAEIH
QAFETMFQES

While a c-Abl protein fragment may be obtained by Factor Xa cleavage, the fragment V228 to S500 obtained by cleavage of SEQ ID NO. 3 with the protease papain is found to crystallize much better than the one obtained from Factor Xa cleavage. Thus, in the present invention, the segment of the human c-Abl protein crystallized in this invention is a fragment of the kinase domain from V228 to S500 (SEQ ID NO. 4) obtained by cleavage with the protease papain. A total of 37 amino acids are removed from the N-terminus of the original construct which is expressed in insect cells and the c-Abl protein fragment obtained from papain cleavage does not contain any amino acid not originating from the human c-Abl sequence.

Human c-abl Kinase Domain (V228 to S500)

[SEQ ID NO. 4]
VSPNYDKWEM ERTDITMKHK LGGGQYGEVY EGVWKKYSLT VAVKTLKEDT MEVEEFLKEA
AVMKETKHPN LVQLLGVCTR EPPFYIITEF MTYGNLLDYL RECNRQEVNA VVLLYMATQI
SSANEYLEKK NFIHRDLAAR NCLVGENHLV KVADFGLSRL MTGDTYTAHA GAKFPIKWTA
PESLAYNKES IKSDVWAFGV LLWEIATYGM SPYPGIDLSQ VYELLEKDYR MERPEGCPEK
VYELMRACWQ WNPSDRPSFA EIHQAFETMF QES

Forty-eight (48) hours after infection, Compound A (discussed below) (10 mM in DMSO) is added to the culture to achieve a final concentration of 3 μM. Twenty-four (24) hours later, cells with a density of 1.5×10⁶ are harvested by centrifugation and the cell pellet stored at −70° C.

Compound A is added to allow complex formation between the c-Abl protein and a compound known to bind to the active site of the protein. Compound A is a polycyclic compound with anti-tumor properties and its structure and synthesis is disclosed in Example 1 of WO 99/02532, the contents of which are hereby incorporated by reference. The chemical structure of Compound A is provided below: Purification

Cells from one 5 L bioreactor (7.5×10⁹ cells total) are lysed in 180 mL of buffer A (50 mM Na-phosphate, 300 mM NaCl, 10 vol % glycerol, 10 mM 2-mercaptoethanol, pH 8) supplemented with a protease inhibitor cocktail (Complete™, EDTA-free, Roche) and 20 μM Compound A (tartrate salt) by sonication at 4-10° C. The lysate is clarified by centrifugation at 45,000×g and 4° C. for 100 minutes and is additionally filtered through a 0.45 μM membrane (Stericup, Millipore). The filtrate (250 mL) is adjusted to pH 8 with NaOH and after addition of 0.5 mL Compound A (10 mM in DMSO) is loaded onto a 18 mL column of Ni-NTA superflow resin (Quiagen) at a flow rate of 100 mL/hour at 4° C. After loading the column is subsequently washed with buffer A containing 10 mM and 15 mM imidazole to remove contaminating proteins. After an additional wash with 15 mM imidazole in buffer B (20 mM tris, 100 mM NaCl, 10 vol % glycerol, 5 mM 2-mercaptoethanol, pH 8 adjusted with HCl at 4° C.) the bound His-Abl is eluted with 50 mL of 100 mM imidazole in buffer B at a flow rate of 60 mL/hour. HPLC analysis indicates that the buffer B wash contains about 6 mg and the 100 mM imidazole eluate about 13 mg His-Abl and co-elution of Compound A is not detectable. Analysis by mass spectrometry indicates that about 50% of the isolated His-Abl is un-phosphorylated, 35% mono- and 15% di-phosphorylated. After addition of 1 mM EDTA, 2 mM DTT and 20 μM Compound A (final concentrations) both solutions are concentrated to 5 mL and 13 mL, respectively and combined. HPLC-analysis of this pool shows a concentration of about 1 mg c-Abl/mL and a molar ratio of c-Abl to Compound A of about 1:1. To remove the His-tag together with 10 amino acids from the N-terminus of c-Abl (amino acids 218-227) 18.5 μg of papain (Roche) is added and the reaction allowed to proceed at 4° C. for 4 hours Papain is inactivated by addition of anti-pain (Roche, 25 μg/mL final concentration). Five hundred (500) units of T-cell protein tyrosine phosphate (New England Biolabs) is added and incubation continued for additional 19 hours at 4° C. to dephosphorylate c-Abl. Compound A is then added to achieve a 2-fold molar excess and the reaction concentrated to 3.5 mL by ultratiltration in a centrifugal filter device with a 10 KDa MW cut-off (Amicon). The concentrate containing about 15 mg of c-Abl and a 1.25 molar excess of Compound A is loaded onto a HiLoad 16/60 Superdex 75 prep grade column (Amersham Biosciences) run in 20 mM Tris, 100 mM NaCl, 0.2 M ethyleneglycol, 1 mM EDTA, 3 mM DTT, pH 7.6 at a flow rate of 1.3 mL/min. The column is cooled by pumping ice water through the column jacket. c-Abl elutes as symmetrical peak at a elution volume corresponding to the monomeric protein, but most of Compound A is lost during size exclusion chromatography. To the Superdex 75 fractions (total 12 mL, 14 mg c-abl) is added 50 μM of Compound A to achieve a 2-fold molar excess over c-Abl, the solution concentrated to 0.6 mL by ultrafiltration and the concentrate centrifuged to remove a small amount of precipitate. HPLC analysis indicates a concentration of 24-25 mg c-Abl/mL and a molar ratio of c-Abl: Compound A of about 1:0.95. The purified c-Abl kinase is at least 95% pure judged by reducing, Coomassie stained SDS-PAGE and by reversed-phase HPLC. Mass spectrometry however shows that about 12% of the protein is still phosphorylated (expected mass: 31 642.3 Da for c-Abl (V228 to S500) unphosphorylated; measured: 31 641.9 Da (−88%); 31 721.5 Da (−12%), +79.6 Da, monophosphorylated). The c-Abl/Compound A complex at this stage of purity and homogeneity is used for crystallization.

EXAMPLE 2

Structure Determination of Human Abl Kinase in Complex with Compound A at 2.8 Å Resolution

Crystallization

Abl protein complexed with Compound A (in ˜24 mg/mL in 20 mM Tris HCl, 100 mM NaCl, 1 mM EDTA, 0.2 M ethylene glycol, pH 7.6, +3 mM DTT) produced as disclosed above is used for crystallization. Crystal growth is obtained after incubation of 1 μL of protein solution with 1 μL of reservoir solution (12% PEG 8000 (w/v), 0.2 M MgAcetate, 0.1 M HEPES pH 7.5) and equilibration through the vapor phase with 1,000 μL of the reservoir solution (12% PEG 8,000 (w/v), 0.2 M MgAcetate, 0.1 M HEPES pH 7.5) at 4° C. using methods familiar to one of skill in the art.

Data Collection

The crystals are gradually transferred over a period of 2 hours to 12% PEG 8,000 (w/v), 0.2 M MgAcetate, 0.1 M HEPES pH 7.5, 25% glycerol, then cryo cooled by dunking in liquid nitrogen and stored in liquid nitrogen. Data are collected at beamline X06SA [Swiss Light Source (SLS) Villigen, Switzerland]. The wavelength of the X-rays is 0.977789 Å and the beam current is 300 mA. The crystal to detector distance is 200 mm and the rotation range for each image is 0.75° with an exposure time of 1.5 seconds, 280 images are collected, but only 214 are used in data processing because radiation damage is obvious in the last images. Data are processed with the HKL package (Zbyszek Otwinowski, University of Texas Southwestern Medical Center, Dallas) and statistics are listed in Table 3.

TABLE 3
Data Collection Statistics
Crystal Size                     0.06 × 0.06 × 0.015 mm3
Number of crystals used for data set 1
Space group                      C2
Unit cell (a, b, c, beta)        182.56 Å, 58.33 Å,
                                 103.99 Å, 119.16°
Images used                      214 (≡160.5°)
Measurements (each partial)      291875
Unique measurements (each reflection) 63157
Unique reflections               22731
Multiplicity                     2.8
Resolution range                 40.0-2.8 Å
Refined mosaicity                1.25°
Completeness (shell 2.9-2.8 Å)   96.2% (83.3%)
Rmerge (shell 2.9-2.8 Å)         0.087 (0.335)
Percentage of data with l/sig(l) ≧ 2 77.3

Structure Determination and Refinement

Molecular replacement is performed using Abl kinase amino acids 235-380 and 401-498 (see Table 4 below).

TABLE 4
Amino Acid Sequence for Molecular Replacement Model
[SEQ ID NO. 5]
235-380:
WEMERTDITM KHKLGGGQYG EVYEGVWKKY SLTVAVKTLK EDTMEVEEFL KEAAVMKEIK
HPNLVQLLGV CTREPPFYII TEFMTYGNLL DYLRECNRQE VSAVVLLYMA TQISSAMEYL
EKKNFIHRDL AARNCLVGEN HLVKVA
[SEQ ID NO. 6]
401-498:
FPIK WTAPESLAYN KFSIKSDVWA FGVLLWEIAT
YGMSPYPGID LSQVYELLEK DYRMERPEGC PEKVYELMRA CWQWNPSDRP SFAEIHQAFE
TMFQ

Based on the cell volume, the expected number of molecules in the asymmetric unit is 3 (52.6% solvent). Molecular replacement (using MolRep, “MOLREP: an automated program for molecular replacement” [see Vagin and Teplyakov, J Appl Cryst, Vol. 30, pp. 1022-1025 (1997)], within the CCP4 suite “The CCP4 suite: Programs for Protein Crystallography” [see Collaborative Computational Project Number 4, Acta Cryst, Vol. D50, pp. 760-763 (1994) gives 2 strong and one weaker peak in the rotation function and a clearly correct solution after placing of all three molecules with the translation function (R-factor 0.485, correlation 0.422, resolution range 40.0-4.0 Å). Refinement is carried out with alternate cycles of model building on the graphics display using the program 0 [see Jones et al., Acta Cryst, vol. A47, pp. 110-119 (1991)] and restrained maximum likelihood refinement with Refmac5. See Murshudov et al., Acta Cryst, Vol. D53, pp. 240-255 (1997).

Tight NCS restraints are used in the initial cycles, but due to differences between the three molecules in the asymmetric unit, these are taken off in the last cycles. Several water molecules are identified from strong difference density and three molecules of a compound referred to herein as Compound A are found and added to the model.

A parameterization of the translation, libration and screw-rotation displacements of all three protein molecules in the asymmetric unit of the crystals is used in the final refinement cycles. See Winn, Isupov and Murshudov, Acta Cryst, Vol. D57 (2001). A summary of the refinement statistics is listed in Table 5.

TABLE 5
Refinement Statistics
Contents of model:
Abl kinase          Residues 234-248, 254-500 (2139
(chain id A)        atoms, av. B = 62.6 Å2)
Abl kinase          Residues 233-248, 254-498 (2134
(chain id B)        atoms, av. B = 56.6 Å2)
Abl kinase          Residues 234-248, 254-264, 267-274,
(chain id C)        276-500 (2115 atoms, av. B = 78.2 Å2)
Compound A          3 × 35 atoms (av. B =
(chains I, J, K)    47.7 Å2, 67.9 Å2, 81.0 Å2)
Water               19 atoms (av. B = 51.5 Å2)
(chain id W)
R-value             0.218
Free R-value        0.287
Mean B-value        63.29 Å2
r.m.s.d values:
bonds               0.020 Å
angles              1.86°
Residues in allowed 99.6% (86.3%)
region of
Ramachandran
plot (core)

Overall Structure

The final structure of Abl in these crystals contains two molecules of Abl kinase with empty ATP binding sites (chains A and C) and one molecule (chain B) with Compound A (chain I) bound in the ATP binding site. The other two Compound A molecules (chains K and J) are hydrogen bonded to the C-terminus of molecules A and C respectively, and are held in place by crystal contacts with other Abl kinase domains. Molecules A and C are related by a local two-fold symmetry axis.

The conformation of all three Abl kinase domains is very similar. There is some shift of the N-terminal lobe with respect to the C-terminal lobe, but the positions of the residues important for catalysis are very similar. A superposition with the activated Lck kinase domain [see Yamaguchi and Hendrickson (1996), supra] shows that Abl is in an active conformation (data not shown). The activation loop including the DFG motif, despite the lack of phosphorylation, follows the same path as in Lck and the catalytic residues, e.g., from helix C, are all correctly positioned.

TABLE 6
Atomic Coordinates for c-Abl Crystal Structure
HEADER		----	XX-XXX-XX xxxx
COMPND		---
REMARK	3
REMARK	3	REFINEMENT.
REMARK	3	PROGRAM:	REFMAC 5.1.9999
REMARK	3	AUTHORS:	MURSHUDOV,
REMARK	3	VAGIN,
REMARK	3	DODSON
REMARK	3
REMARK	3	REFINEMENT TARGET:	MAXIMUM
REMARK	3	LIKELIHOOD
REMARK	3
REMARK	3	DATA USED IN REFINEMENT.
REMARK	3	RESOLUTION RANGE HIGH (ANGSTROMS):	2.80
REMARK	3	RESOLUTION RANGE LOW (ANGSTROMS):	40.00
REMARK	3	DATA CUTOFF (SIGMA(F)):	NONE
REMARK	3	COMPLETENESS FOR RANGE	(%):	96.24
REMARK	3	NUMBER OF REFLECTIONS:	22372
REMARK	3
REMARK	3	FIT TO DATA USED IN REFINEMENT.
REMARK	3	CROSS-VALIDATION METHOD:	THROUGHOUT
REMARK	3	FREE R VALUE TEST SET SELECTION:	RANDOM
REMARK	3	R VALUE (WORKING + TEST SET):	0.21990
REMARK	3	R VALUE (WORKING SET):	0.21644
REMARK	3	FREE R VALUE:	0.28505
REMARK	3	FREE R VALUE TEST SET SIZE (%):	5.1
REMARK	3	FREE R VALUE TEST SET COUNT:	1203
REMARK	3
REMARK	3	FIT IN THE HIGHEST RESOLUTION BIN.
REMARK	3	TOTAL NUMBER OF BINS USED:	20
REMARK	3	BIN RESOLUTION RANGE HIGH:	2.800
REMARK	3	BIN RESOLUTION RANGE LOW:	2.872
REMARK	3	REFLECTION IN BIN (WORKING SET):	1330
REMARK	3	BIN R VALUE (WORKING SET):	0.335
REMARK	3	BIN FREE R VALUE SET COUNT:	60
REMARK	3	BIN FREE R VALUE:	0.399
REMARK	3
REMARK	3	NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.
REMARK	3	ALL ATOMS:	6518
REMARK	3
REMARK	3	B VALUES.
REMARK	3	FROM WILSON PLOT (A**2):	NULL
REMARK	3	MEAN B VALUE (OVERALL, A**2):	63.614
REMARK	3	OVERALL ANISOTROPIC B VALUE.
REMARK	3	B11 (A**2):	−1.42
REMARK	3	B22 (A**2):	6.00
REMARK	3	B33 (A**2):	−5.84
REMARK	3	B12 (A**2):	0.00
REMARK	3	B13 (A**2):	−1.30
REMARK	3	B23 (A**2):	0.00
REMARK	3
REMARK	3	ESTIMATED OVERALL COORDINATE ERROR.
REMARK	3	ESU BASED ON R VALUE (A):	NULL
REMARK	3	ESU BASED ON FREE R VALUE (A):	0.444
REMARK	3	ESU BASED ON MAXIMUM LIKELIHOOD (A):	0.326
REMARK	3	ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2):	36.309
REMARK	3
REMARK	3	CORRELATION COEFFICIENTS.
REMARK	3	CORRELATION COEFFICIENT FO-FC:	0.935
REMARK	3	CORRELATION COEFFICIENT FO-FC FREE:	0.885
REMARK	3
REMARK	3	RMS DEVIATIONS FROM IDEAL VALUES	COUNT	RMS	WEIGHT
REMARK	3	BOND LENGTHS REFINED ATOMS (A):	6680	0.020	0.022
REMARK	3	BOND LENGTHS OTHERS (A):	5965	0.003	0.020
REMARK	3	BOND ANGLES REFINED ATOMS (DEGREES):	9067	1.869	1.966
REMARK	3	BOND ANGLES OTHERS (DEGREES):	13898	1.315	3.000
REMARK	3	TORSION ANGLES, PERIOD 1 (DEGREES):	771	8.781	5.000
REMARK	3	TORSION ANGLES, PERIOD 2 (DEGREES):	308	39.831	24.156
REMARK	3	TORSION ANGLES, PERIOD 3 (DEGREES):	1169	18.050	15.000
REMARK	3	TORSION ANGLES, PERIOD 4 (DEGREES):	33	19.175	15.000
REMARK	3	CHIRAL-CENTER RESTRAINTS (A**3):	964	0.102	0.200
REMARK	3	GENERAL PLANES REFINED ATOMS (A):	7218	0.007	0.020
REMARK	3	GENERAL PLANES OTHERS (A):	1365	0.003	0.020
REMARK	3	NON-BONDED CONTACTS REFINED ATOMS (A):	1317	0.189	0.200
REMARK	3	NON-BONDED CONTACTS OTHERS (A):	5686	0.130	0.200
REMARK	3	NON-BONDED TORSION OTHERS (A):	3612	0.077	0.200
REMARK	3	H-BOND (X. . .Y) REFINED ATOMS (A):	194	0.137	0.200
REMARK	3	SYMMETRY VDW REFINED ATOMS (A):	22	0.141	0.200
REMARK	3	SYMMETRY VDW OTHERS (A):	64	0.142	0.200
REMARK	3	SYMMETRY H-BOND REFINED ATOMS (A):	7	0.159	0.200
REMARK	3
REMARK	3	ISOTROPIC THERMAL FACTOR RESTRAINTS.	COUNT	RMS	WEIGHT
REMARK	3	MAIN-CHAIN BOND REFINED ATOMS (A**2):	4498	0.765	1.500
REMARK	3	MAIN-CHAIN BOND OTHER ATOMS (A**2):	1573	0.122	1.500
REMARK	3	MAIN-CHAIN ANGLE REFINED ATOMS (A**2):	6297	1.100	2.000
REMARK	3	SIDE-CHAIN BOND REFINED ATOMS (A**2):	3667	1.368	3.000
REMARK	3	SIDE-CHAIN ANGLE REFINED ATOMS (A**2):	2770	2.264	4.500
REMARK	3
REMARK	3	NCS RESTRAINTS STATISTICS
REMARK	3	NUMBER OF NCS GROUPS: NULL
REMARK	3
REMARK	3
REMARK	3	TLS DETAILS
REMARK	3	NUMBER OF TLS GROUPS: 6
REMARK	3
REMARK	3	TLS GROUP: 1
REMARK	3	NUMBER OF COMPONENTS GROUP: 1
REMARK	3	COMPONENTS	C SSSEQI TO C SSSEQI
REMARK	3	RESIDUE RANGE:	A   234     A   318
REMARK	3	ORIGIN FOR THE GROUP (A): 33.1740	0.3010	37.1720
REMARK	3	T TENSOR
REMARK	3	T11:	−0.1258	T22:	0.1688
REMARK	3	T33:	−0.1102	T12:	0.0875
REMARK	3	T13:	−0.0254	T23:	−0.0041
REMARK	3	L TENSOR
REMARK	3	L11:	4.2002	L22:	4.5001
REMARK	3	L33:	4.3983	L12:	0.4480
REMARK	3	L13:	−0.7500	L23:	−0.3640
REMARK	3	S TENSOR
REMARK	3	S11:	0.3150	S12:	−0.2302	S13:	−0.0056
REMARK	3	S21:	0.6499	S22:	−0.1337	S23:	0.4308
REMARK	3	S31:	−0.2533	S32:	−0.4923	S33:	−0.1813
REMARK	3
REMARK	3	TLS GROUP : 2
REMARK	3	NUMBER OF COMPONENTS GROUP: 2
REMARK	3	COMPONENTS	C SSSEQI TO C SSSEQI
REMARK	3	RESIDUE RANGE:	A   319     A   500
REMARK	3	RESIDUE RANGE:	I   501     I   501
REMARK	3	ORIGIN FOR THE GROUP (A):	57.0230	0.5150	27.0400
REMARK	3	T TENSOR
REMARK	3	T11:	0.0306	T22:	−0.1866
REMARK	3	T33:	0.0244	T12:	0.0591
REMARK	3	T13:	−0.0248	T23:	0.0154
REMARK	3	L TENSOR
REMARK	3	L11:	1.7326	L22:	1.4053
REMARK	3	L33:	1.5694	L12:	−0.4819
REMARK	3	L13:	−1.0195	L23:	0.6939
REMARK	3	S TENSOR
REMARK	3	S11:	0.1908	S12:	0.2970	S13:	−0.0068
REMARK	3	S21:	−0.1108	S22:	0.1466	S23:	0.0678
REMARK	3	S31:	−0.1679	S32:	0.3014	S33:	0.0442
REMARK	3
REMARK	3	TLS GROUP : 3
REMARK	3	NUMBER OF COMPONENTS GROUP: 1
REMARK	3	COMPONENTS	C SSSEQI TO C SSSEQI
REMARK	3	RESIDUE RANGE:	B   233     B   318
REMARK	3	ORIGIN FOR THE GROUP (A):	42.7060	12.2540	65.8540
REMARK	3	T TENSOR
REMARK	3	T11:	0.0983	T22:	−0.2988
REMARK	3	T33:	0.1021	T12:	−0.0617
REMARK	3	T13:	0.0974	T23:	−0.0054
REMARK	3	L TENSOR
REMARK	3	L11:	4.3243	L22:	5.7869
REMARK	3	L33:	3.8414	L12:	0.1164
REMARK	3	L13:	−0.8713	L23:	0.5655
REMARK	3	S TENSOR
REMARK	3	S11:	−0.2374	S12:	0.5340	S13:	0.5608
REMARK	3	S21:	0.7627	S22:	−0.0670	S23:	0.2730
REMARK	3	S31:	0.3596	S32:	−0.2658	S33:	0.3043
REMARK	3
REMARK	3	TLS GROUP : 4
REMARK	3	NUMBER OF COMPONENTS GROUP: 2
REMARK	3	COMPONENTS	C SSSEQI TO C SSSEQI
REMARK	3	RESIDUE RANGE:	B   319     B   498
REMARK	3	RESIDUE RANGE:	J   501     J   501
REMARK	3	ORIGIN FOR THE GROUP (A):	49.06	33.2100	53.2640
REMARK	3	T TENSOR
REMARK	3	T11:	0.0147	T22:	ta,32 −0.1809
REMARK	3	T33:	0.0790	T12:	0.0262
REMARK	3	T13:	−0.0005	T23:	0.0182
REMARK	3	L TENSOR
REMARK	3	L11:	0.7064	L22:	1.3543
REMARK	3	L33:	0.8307	L12:	0.2355
REMARK	3	L13:	0.5106	L23:	0.4316
REMARK	3	S TENSOR
REMARK	3	S11:	0.0778	S12:	0.0331	S13:	0.0008
REMARK	3	S21:	−0.0287	S22:	0.1143	S23:	0.0500
REMARK	3	S31:	−0.1019	S32:	0.1826	S33:	0.0366
REMARK	3
REMARK	3	TLS GROUP: 5
REMARK	3	NUMBER OF COMPONENTS GROUP: 1
REMARK	3	COMPONENTS	C SSSEQI TO C SSSEQI
REMARK	3	RESIDUE RANGE:	C   234     C   318
REMARK	3	ORIGIN FOR THE GROUP (A):	38.3990	−2.2700	−4.7780
REMARK	3	T TENSOR
REMARK	3	T11:	0.0724	T22:	0.0739
REMARK	3	T33:	−0.0972	T12:	0.1733
REMARK	3	T13:	0.0996	T23:	0.1977
REMARK	3	L TENSOR
REMARK	3	L11:	3.6132	L22:	2.3842
REMARK	3	L33:	3.5724	L12:	−2.1106
REMARK	3	L13:	−1.0922	L23:	0.9867
REMARK	3	S TENSOR
REMARK	3	S11:	−0.4434	S12:	−0.4700	S13:	−0.2869
REMARK	3	S21:	−0.1804	S22:	0.1448	S23:	0.0240
REMARK	3	S31:	0.7706	S32:	0.5263	S33:	0.2986
REMARK	3
REMARK	3	TLS GROUP: 6
REMARK	3	NUMBER OF COMPONENTS GROUP: 2
REMARK	3	COMPONENTS: C SSSEQI TO C SSSEQI
REMARK	3	RESIDUE RANGE	C   319     C   500
REMARK	3	RESIDUE RANGE:	K   501     K   501
REMARK	3	ORIGIN FOR THE GROUP (A):	19.4870	10.3820	5.7900
REMARK	3	T TENSOR
REMARK	3	T11:	−0.0708	T22:	−0.1500
REMARK	3	T33:	−0.1131	T12:	−0.0134
REMARK	3	T13:	−0.0050	T23:	0.0785
REMARK	3	L TENSOR
REMARK	3	L11:	5.3830	L22:	0.2782
REMARK	3	L33:	9.0399	L12:	0.3295
REMARK	3	L13:	−5.3853	L23:	−0.7917
REMARK	3	S TENSOR
REMARK	3	S11:	−0.0185	S12:	−0.3576	S13:	0.1481
REMARK	3	S21:	−0.0292	S22:	0.0844	S23:	0.0728
REMARK	3	S31:	−0.0448	S32:	0.3330	S33:	−0.0659
REMARK	3
REMARK	3
REMARK	3	BULK SOLVENT MODELLING.
REMARK	3	METHOD USED: BABINET MODEL WITH MASK
REMARK	3	PARAMETERS FOR MASK CALCULATION
REMARK	3	VDW PROBE RADIUS: 1.20
REMARK	3	ION PROBE RADIUS: 0.80
REMARK	3	SHRINKAGE RADIUS: 0.80
REMARK	3
REMARK	3	OTHER REFINEMENT REMARKS:
REMARK	3	HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
REMARK	3
LINK		LEU A 248	GLY A 254	gap
LINK		PRO A 309	PRO A 310	PNCIS
LINK		LEU B 248	GLY B 254	gap
LINK		PRO B 309	PRO B 310	PNCIS
LINK		LEU C 248	GLY C 254	gap
LINK		TYR C 264	THR C 267	gap
LINK		LYS C 274	ASP C 276	gap
LINK		PRO C 309	PRO C 310	PNCIS
REMARK	465
REMARK	465	MISSING RESIDUES
REMARK	465	THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK	465	EXPERIMENT. (M = MODEL NUMBER; RES = RESIDUE NAME; C = CHAIN
REMARK	465	IDENTIFIER; SSSEQ = SEQUENCE NUMBER; I = INSERTION CODE.)
REMARK	465
REMARK	465	M	RES C	SSSEQI
REMARK	465		VAL A	228
REMARK	465		SER A	229
REMARK	465		PRO A	230
REMARK	465		ASN A	231
REMARK	465		TYR A	232
REMARK	465		ASP A	233
REMARK	465		GLY A	249
REMARK	465		GLY A	250
REMARK	465		GLY A	251
REMARK	465		GLN A	252
REMARK	465		TYR A	253
REMARK	465		VAL B	228
REMARK	465		SER B	229
REMARK	465		PRO B	230
REMARK	465		ASN B	231
REMARK	465		TYR B	232
REMARK	465		GLY B	249
REMARK	465		GLY B	250
REMARK	465		GLY B	251
REMARK	465		GLN B	252
REMARK	465		TYR B	253
REMARK	465		GLU B	499
REMARK	465		SER B	500
REMARK	465		VAL C	228
REMARK	465		SER C	229
REMARK	465		PRO C	230
REMARK	465		ASN C	231
REMARK	465		TYR C	232
REMARK	465		ASP C	233
REMARK	465		GLY C	249
REMARK	465		GLY C	250
REMARK	465		GLY C	251
REMARK	465		GLN C	252
REMARK	465		TYR C	253
REMARK	465		SER C	265
REMARK	465		LEU C	266
REMARK	465		GLU C	275
SEQRES	1	A	273	VAL SER PRO ASN TYR ASP LYS TRP GLU MET GLU ARG THR
SEQRES	2	A	273	ASP ILE THR MET LYS HIS LYS LEU GLY GLY GLY GLN TYR
SEQRES	3	A	273	GLY GLU VAL TYR GLU GLY VAL TRP LYS LYS TYR SER LEU
SEQRES	4	A	273	THR VAL ALA VAL LYS THR LEU LYS GLU ASP THR MET GLU
SEQRES	5	A	273	VAL GLU GLU PHE LEU LYS GLU ALA ALA VAL MET LYS GLU
SEQRES	6	A	273	ILE LYS HIS PRO ASN LEU VAL GLN LEU LEU GLY VAL CYS
SEQRES	7	A	273	THR ARG GLU PRO PRO PHE TYR ILE ILE THR GLU PHE MET
SEQRES	8	A	273	THR TYR GLY ASN LEU LEU ASP TYR LEU ARG GLU CYS ASN
SEQRES	9	A	273	ARG GLN GLU VAL ASN ALA VAL VAL LEU LEU TYR MET ALA
SEQRES	10	A	273	THR GLN ILE SER SER ALA MET GLU TYR LEU GLU LYS LYS
SEQRES	11	A	273	ASN PHE ILE HIS ARG ASP LEU ALA ALA ARG ASN CYS LEU
SEQRES	12	A	273	VAL GLY GLU ASN HIS LEU VAL LYS VAL ALA ASP PHE GLY
SEQRES	13	A	273	LEU SER ARG LEU MET THR GLY ASP THR TYR THR ALA HIS
SEQRES	14	A	273	ALA GLY ALA LYS PHE PRO ILE LYS TRP THR ALA PRO GLU
SEQRES	15	A	273	SER LEU ALA TYR ASN LYS PHE SER ILE LYS SER ASP VAL
SEQRES	16	A	273	TRP ALA PHE GLY VAL LEU LEU TRP GLU ILE ALA TER TYR
SEQRES	17	A	273	GLY MET SER PRO TYR PRO GLY ILE ASP LEU SER GLN VAL
SEQRES	18	A	273	TYR GLU LEU LEU GLU LYS ASP TYR ARG MET GLU ARG PRO
SEQRES	19	A	273	GLU GLY CYS PRO GLU LYS VAL TYR GLU LEU MET ARG ALA
SEQRES	20	A	273	CYS TRP GLN TRP ASN PRO SER ASP ARG PRO SER PHE ALA
SEQRES	21	A	273	GLU ILE HIS GLN ALA PHE GLU THR MET PHE GLN GLU SER
SEQRES	22	B	273	VAL SER PRO ASN TYR ASP LYS TRP GLU MET GLU ARG THR
SEQRES	23	B	273	ASP ILE THR MET LYS HIS LYS LEU GLY GLY GLY GLN TYR
SEQRES	24	B	273	GLY GLU VAL TYR GLU GLY VAL TRP LYS LYS TYR SER LEU
SEQRES	25	B	273	THR VAL ALA VAL LYS THR LEU LYS GLU ASP THR MET GLU
SEQRES	26	B	273	VAL GLU GLU PHE LEU LYS GLU ALA ALA VAL MET LYS GLU
SEQRES	27	B	273	ILE LYS HIS PRO ASN LEU VAL GLN LEU LEU GLY VAL CYS
SEQRES	28	B	273	THR ARG GLU PRO PRO PHE TYR ILE ILE THR GLU PHE MET
SEQRES	29	B	273	THR TYR GLY ASN LEU LEU ASP TYR LEU ARG GLU CYS ASN
SEQRES	30	B	273	ARG GLN GLU VAL ASN ALA VAL VAL LEU LEU TYR MET ALA
SEQRES	31	B	273	THR GLN ILE SEE SER ALA MET GLU TYR LEU GLU LYS LYS
SEQRES	32	B	273	ASN PHE ILE HIS ARG ASP LEU ALA ALA ARG ASN CYS LEU
SEQRES	33	B	273	VAL GLY GLU ASN HIS LEU VAL LYS VAL ALA ASP PHE GLY
SEQRES	34	B	273	LEU SER ARG LEU MET THR GLY ASP THR TYR THR ALA HIS
SEQRES	35	B	273	ALA GLY ALA LYS PHE PRO ILE LYS TRP THR ALA PRO GLU
SEQRES	36	B	273	SER LEU ALA TYR ASN LYS PHE SER ILE LYS SER ASP VAL
SEQRES	37	B	273	TRP ALA PHE GLY VAL LEU LEU TRP GLU ILE ALA THR TYR
SEQRES	38	B	273	GLY MET SER PRO TYR PRO GLY ILE ASP LEU SER GLN VAL
SEQRES	39	B	273	TYR GLU LEU LEU GLU LYS ASP TYR ARG MET GLU ARG PRO
SEQRES	40	B	273	GLU GLY CYS PRO GLU LYS VAL TYR GLU LEU MET ARG ALA
SEQRES	41	B	273	CYS TRP GLN TRP ASN PRO SER ASP ARG PRO SER PHE ALA
SEQRES	42	B	273	GLU ILE HIS GLN ALA PHE GLU THR MET PHE GLN GLU SER
SEQRES	43	C	273	VAL SER PRO ASN TYR ASP LYS TRP GLU MET GLU ARG THR
SEQRES	44	C	273	ASP ILE THR MET LYS HIS LYS LEU GLY GLY GLY GLN TYR
SEQRES	45	C	273	GLY GLU VAL TYR GLU GLY VAL TRP LYS LYS TYR SER LEU
SEQRES	46	C	273	THR VAL ALA VAL LYS THR LEU LYS GLU ASP THR MET GLU
SEQRES	47	C	273	VAL GLU GLU PHE LEU LYS GLU ALA ALA VAL MET LYS GLU
SEQRES	48	C	273	ILE LYS HIS PRO ASN LEU VAL GLN LEU LEU GLY VAL CYS
SEQRES	49	C	273	THR ARG GLU PRO PRO PHE TYR ILE ILE THR GLU PHE MET
SEQRES	50	C	273	THR TYR GLY ASN LEU LEU ASP TYR LEU ARG GLU CYS ASN
SEQRES	51	C	273	ARG GLN GLU VAL ASN ALA VAL VAL LEU LEU TYR MET ALA
SEQRES	52	C	273	THR GLN ILE SER SER ALA MET GLU TYR LEU GLU LYS LYS
SEQRES	53	C	273	ASN PHE ILE HIS ARG ASP LEU ALA ALA ARG ASN CYS LEU
SEQRES	54	C	273	VAL GLY GLU ASN HIS LEU VAL LYS VAL ALA ASP PHE GLY
SEQRES	55	C	273	LEU SER ARG LEU MET THR GLY ASP THR TYR THR ALA HIS
SEQRES	56	C	273	ALA GLY ALA LYS PHE PRO ILE LYS TRP THR ALA PRO GLU
SEQRES	57	C	273	SER LEU ALA TYR ASN LYS PHE SER ILE LYS SER ASP VAL
SEQRES	58	C	273	TRP ALA PHE GLY VAL LEU LEU TRP GLU ILE ALA THR TYR
SEQRES	59	C	273	GLY MET SER PRO TYR PRO GLY ILE ASP LEU SER GLN VAL
SEQRES	60	C	273	TYR GLU LEU LEU GLU LYS ASP TYR ARG MET GLU ARG PRO
SEQRES	61	C	273	GLU GLY CYS PRO GLU LYS VAL TYR GLU LEU MET ARG ALA
SEQRES	62	C	273	CYS TRP GLN TRP ASN PRO SER ASP ARG PRO SER PHE ALA
SEQRES	63	C	273 GLU ILE HIS GLN ALA PHE GLU THR MET PHE GLN GLU SER
CRYST1	185.447	58.853	103.977	90.00	119.02	90.00	C 1 2 1
SCALE1	0.005392	0.000000	0.002991	0.00000
SCALE2	0.000000	0.016991	0.000000	0.00000
SCALE3	0.000000	0.000000	0.010998	0.00000
ATOM	1	N	LYS	A	234	26.818	13.365	34.898	1.00	78.16	N
ATOM	2	CA	LYS	A	234	27.472	12.325	35.718	1.00	78.53	C
ATOM	4	CB	LYS	A	234	26.778	12.076	37.074	1.00	78.69	C
ATOM	7	CG	LYS	A	234	26.818	13.199	38.038	1.00	79.58	C
ATOM	10	CD	LYS	A	234	28.206	13.505	38.576	1.00	80.52	C
ATOM	13	CE	LYS	A	234	28.126	14.765	39.474	1.00	80.97	C
ATOM	16	NZ	LYS	A	234	29.426	15.471	39.604	1.00	81.71	N
ATOM	20	C	LYS	A	234	27.549	10.992	35.015	1.00	78.86	C
ATOM	21	O	LYS	A	234	26.839	10.726	34.043	1.00	78.12	O
ATOM	25	N	TRP	A	235	28.450	10.190	35.584	1.00	79.48	N
ATOM	26	CA	TRP	A	235	28.766	8.811	35.242	1.00	79.74	C
ATOM	28	CB	TRP	A	235	30.283	8.615	35.291	1.00	80.07	C
ATOM	31	CG	TRP	A	235	31.057	9.632	34.521	1.00	80.26	C
ATOM	32	CD1	TRP	A	235	31.312	10.931	34.883	1.00	80.10	C
ATOM	34	NE1	TRP	A	235	32.055	11.554	33.911	1.00	80.57	N
ATOM	36	CE2	TRP	A	235	32.303	10.660	32.902	1.00	80.38	C
ATOM	37	CD2	TRP	A	235	31.684	9.435	33.259	1.00	80.12	C
ATOM	38	CE3	TRP	A	235	31.787	8.346	32.380	1.00	80.41	C
ATOM	40	CZ3	TRP	A	235	32.502	8.511	31.189	1.00	80.75	C
ATOM	42	CH2	TRP	A	235	33.102	9.747	30.864	1.00	80.77	C
ATOM	44	CZ2	TRP	A	235	33.021	10.826	31.709	1.00	80.35	C
ATOM	46	C	TRP	A	235	28.160	7.868	36.259	1.00	79.87	C
ATOM	47	O	TRP	A	235	28.013	6.678	36.000	1.00	79.41	O
ATOM	49	N	GLU	A	236	27.923	8.397	37.458	1.00	80.54	N
ATOM	50	CA	GLU	A	236	27.007	7.819	38.431	1.00	81.08	C
ATOM	52	CB	GLU	A	236	26.608	8.856	39.505	1.00	81.08	C
ATOM	55	CG	GLU	A	236	27.618	8.953	40.647	1.00	81.29	C
ATOM	58	CD	GLU	A	236	27.762	7.660	41.444	1.00	80.91	C
ATOM	59	OE1	GLU	A	236	26.846	6.802	41.428	1.00	81.58	O
ATOM	60	OE2	GLU	A	236	28.804	7.480	42.089	1.00	79.08	O
ATOM	61	C	GLU	A	236	25.755	7.204	37.820	1.00	81.19	C
ATOM	62	O	GLU	A	236	25.034	7.862	37.062	1.00	81.13	O
ATOM	64	N	MET	A	237	25.546	5.933	38.156	1.00	81.30	N
ATOM	65	CA	MET	A	237	24.476	5.131	37.602	1.00	81.81	C
ATOM	67	CB	MET	A	237	24.896	4.640	36.209	1.00	81.98	C
ATOM	70	CG	MET	A	237	26.044	3.646	36.188	1.00	83.64	C
ATOM	73	SD	MET	A	237	25.463	1.940	36.032	1.00	87.27	S
ATOM	74	CE	MET	A	237	25.986	1.190	37.497	1.00	86.41	C
ATOM	78	C	MET	A	237	24.082	3.993	38.579	1.00	81.67	C
ATOM	79	O	MET	A	237	24.632	3.891	39.683	1.00	81.67	O
ATOM	81	N	GLU	A	238	23.140	3.150	38.163	1.00	81.49	N
ATOM	82	CA	GLU	A	238	22.421	2.269	39.068	1.00	81.47	C
ATOM	84	CB	GLU	A	238	20.909	2.315	38.738	1.00	81.55	C
ATOM	87	CG	GLU	A	238	19.998	1.412	39.562	1.00	81.65	C
ATOM	90	CD	GLU	A	238	20.276	1.457	41.059	1.00	81.86	C
ATOM	91	OE1	GLU	A	238	19.951	2.470	41.713	1.00	83.01	O
ATOM	92	OE2	GLU	A	238	20.831	0.480	41.580	1.00	80.92	O
ATOM	93	C	GLU	A	238	22.985	0.840	39.030	1.00	81.31	C
ATOM	94	O	GLU	A	238	22.810	0.112	38.048	1.00	81.40	O
ATOM	96	N	ARG	A	239	23.703	0.496	40.102	1.00	81.18	N
ATOM	97	CA	ARG	A	239	24.079	−0.872	40.513	1.00	81.06	C
ATOM	99	CB	ARG	A	239	23.987	−0.932	42.037	1.00	81.08	C
ATOM	102	CG	ARG	A	239	24.233	−2.292	42.715	1.00	80.93	C
ATOM	105	CD	ARG	A	239	24.461	−2.217	44.238	1.00	80.06	C
ATOM	108	NE	ARG	A	239	25.195	−1.006	44.639	1.00	79.61	N
ATOM	110	CZ	ARG	A	239	26.489	−0.735	44.376	1.00	77.88	C
ATOM	111	NH1	ARG	A	239	27.255	−1.600	43.701	1.00	76.95	N
ATOM	114	NH2	ARG	A	239	27.006	0.427	44.790	1.00	76.22	N
ATOM	117	C	ARG	A	239	23.245	−2.005	39.940	1.00	81.74	C
ATOM	118	O	ARG	A	239	23.794	−2.917	39.320	1.00	82.14	O
ATOM	120	N	THR	A	240	21.926	−1.917	40.158	1.00	82.28	N
ATOM	121	CA	THR	A	240	20.937	−2.963	39.827	1.00	82.51	C
ATOM	123	CB	THR	A	240	19.536	−2.506	40.239	1.00	82.46	C
ATOM	125	OG1	THR	A	240	19.579	−1.976	41.558	1.00	81.86	O
ATOM	127	CG2	THR	A	240	18.553	−3.670	40.339	1.00	82.61	C
ATOM	131	C	THR	A	240	20.877	−3.336	38.363	1.00	83.25	C
ATOM	132	O	THR	A	240	20.510	−4.462	38.049	1.00	83.29	O
ATOM	134	N	ASP	A	241	21.243	−2.409	37.472	1.00	84.25	N
ATOM	135	CA	ASP	A	241	21.297	−2.700	36.021	1.00	85.16	C
ATOM	137	CB	ASP	A	241	21.595	−1.436	35.172	1.00	85.09	C
ATOM	140	CG	ASP	A	241	20.594	−0.286	35.372	1.00	85.12	C
ATOM	141	OD1	ASP	A	241	19.460	−0.512	35.871	1.00	85.91	O
ATOM	142	OD2	ASP	A	241	20.880	0.892	35.024	1.00	82.69	O
ATOM	143	C	ASP	A	241	22.322	−3.802	35.604	1.00	85.66	C
ATOM	144	O	ASP	A	241	22.244	−4.287	34.467	1.00	86.40	O
ATOM	146	N	ILE	A	242	23.245	−4.203	36.491	1.00	85.57	N
ATOM	147	CA	ILE	A	242	24.346	−5.096	36.135	1.00	85.67	C
ATOM	149	CB	ILE	A	242	25.684	−4.390	36.511	1.00	86.01	C
ATOM	151	CG1	ILE	A	242	25.948	−3.260	35.500	1.00	86.69	C
ATOM	154	CD1	ILE	A	242	26.758	−2.134	36.054	1.00	87.46	C
ATOM	158	CG2	ILE	A	242	26.911	−5.364	36.561	1.00	85.74	C
ATOM	162	C	ILE	A	242	24.226	−6.496	36.747	1.00	85.61	C
ATOM	163	O	ILE	A	242	24.393	−6.660	37.946	1.00	85.93	O
ATOM	165	N	THR	A	243	23.963	−7.501	35.915	1.00	85.46	N
ATOM	166	CA	THR	A	243	24.156	−8.909	36.309	1.00	85.54	C
ATOM	168	CB	THR	A	243	23.537	−9.883	35.234	1.00	85.52	C
ATOM	170	OG1	THR	A	243	22.120	−9.986	35.422	1.00	84.66	O
ATOM	172	CG2	THR	A	243	24.031	−11.347	35.374	1.00	85.36	C
ATOM	176	C	THR	A	243	25.656	−9.140	36.424	1.00	85.52	C
ATOM	177	O	THR	A	243	26.337	−8.984	35.427	1.00	85.69	O
ATOM	179	N	MET	A	244	26.167	−9.499	37.603	1.00	85.53	N
ATOM	180	CA	MET	A	244	27.580	−9.934	37.728	1.00	85.86	C
ATOM	182	CB	MET	A	244	28.085	−9.803	39.170	1.00	85.70	C
ATOM	185	CG	MET	A	244	28.112	−8.375	39.709	1.00	85.54	C
ATOM	188	SD	MET	A	244	29.385	−7.266	39.012	1.00	86.87	S
ATOM	189	CE	MET	A	244	30.875	−7.696	40.018	1.00	87.07	C
ATOM	193	C	MET	A	244	27.782	−11.381	37.206	1.00	86.18	C
ATOM	194	O	MET	A	244	26.801	−12.120	37.033	1.00	86.44	O
ATOM	196	N	LYS	A	245	29.043	−11.763	36.937	1.00	86.44	N
ATOM	197	CA	LYS	A	245	29.409	−13.137	36.496	1.00	86.63	C
ATOM	199	CB	LYS	A	245	29.563	−13.206	34.970	1.00	86.76	C
ATOM	202	CG	LYS	A	245	28.215	−13.142	34.218	1.00	86.71	C
ATOM	205	CD	LYS	A	245	28.247	−13.856	32.849	1.00	86.59	C
ATOM	208	CE	LYS	A	245	26.887	−14.432	32.489	1.00	86.97	C
ATOM	211	NZ	LYS	A	245	25.759	−13.459	32.726	1.00	87.93	N
ATOM	215	C	LYS	A	245	30.615	−13.792	37.219	1.00	86.82	C
ATOM	216	O	LYS	A	245	30.406	−14.733	37.985	1.00	87.03	O
ATOM	218	N	HIS	A	246	31.846	−13.333	36.991	1.00	86.96	N
ATOM	219	CA	HIS	A	246	33.037	−14.010	37.569	1.00	87.20	C
ATOM	221	CB	HIS	A	246	33.264	−15.363	36.865	1.00	87.43	C
ATOM	224	CG	HIS	A	246	33.300	−15.259	35.370	1.00	87.88	C
ATOM	225	ND1	HIS	A	246	34.372	−14.723	34.685	1.00	87.72	N
ATOM	227	CE1	HIS	A	246	34.122	−14.751	33.390	1.00	87.65	C
ATOM	229	NE2	HIS	A	246	32.921	−15.274	33.209	1.00	88.08	N
ATOM	231	CD2	HIS	A	246	32.385	−15.598	34.431	1.00	88.07	C
ATOM	233	C	HIS	A	246	34.328	−13.205	37.466	1.00	87.24	C
ATOM	234	O	HIS	A	246	34.415	−12.279	36.659	1.00	87.14	O
ATOM	236	N	LYS	A	247	35.343	−13.649	38.217	1.00	87.30	N
ATOM	237	CA	LYS	A	247	36.687	−13.015	38.257	1.00	87.60	C
ATOM	239	CB	LYS	A	247	37.676	−13.739	39.200	1.00	87.74	C
ATOM	242	CG	LYS	A	247	37.220	−13.966	40.654	1.00	87.39	C
ATOM	245	CD	LYS	A	247	37.494	−15.411	41.116	1.00	86.50	C
ATOM	248	CE	LYS	A	247	36.404	−15.928	42.014	1.00	86.08	C
ATOM	251	NZ	LYS	A	247	36.583	−17.383	42.190	1.00	84.97	N
ATOM	255	C	LYS	A	247	37.367	−12.956	36.895	1.00	87.89	C
ATOM	256	O	LYS	A	247	37.052	−13.741	36.006	1.00	87.86	O
ATOM	258	N	LEU	A	248	38.342	−12.04	8 36.791	1.00	88.30	N
ATOM	259	CA	LEU	A	248	38.956	−11.66	3 35.524	1.00	88.54	C
ATOM	261	CB	LEU	A	248	38.469	−10.259	35.116	1.00	88.42	C
ATOM	264	CG	LEU	A	248	38.095	−10.118	33.629	1.00	89.36	C
ATOM	266	CD1	LEU	A	248	36.673	−10.649	33.379	1.00	88.25	C
ATOM	270	CD2	LEU	A	248	38.272	−8.655	33.057	1.00	89.70	C
ATOM	274	C	LEU	A	248	40.470	−11.714	35.658	1.00	88.12	C
ATOM	275	O	LEU	A	248	41.055	−12.791	35.545	1.00	87.99	O
ATOM	277	N	GLY	A	254	42.071	−4.427	44.620	1.00	88.95	N
ATOM	278	CA	GLY	A	254	40.680	−4.664	44.224	1.00	89.27	C
ATOM	281	C	GLY	A	254	40.501	−5.449	42.920	1.00	89.51	C
ATOM	282	O	GLY	A	254	41.369	−5.399	42.038	1.00	89.70	O
ATOM	284	N	GLU	A	255	39.344	−6.117	42.786	1.00	89.44	N
ATOM	285	CA	GLU	A	255	39.090	−7.168	41.755	1.00	88.99	C
ATOM	287	CB	GLU	A	255	38.439	−8.396	42.415	1.00	88.93	C
ATOM	290	CG	GLU	A	255	39.408	−9.201	43.283	1.00	89.57	C
ATOM	293	CD	GLU	A	255	38.744	−10.069	44.357	1.00	89.88	C
ATOM	294	OE1	GLU	A	255	37.533	−9.895	44.674	1.00	90.32	O
ATOM	295	OE2	GLU	A	255	39.460	−10.939	44.907	1.00	90.32	O
ATOM	296	C	GLU	A	255	38.210	−6.715	40.579	1.00	88.56	C
ATOM	297	O	GLU	A	255	37.374	−5.838	40.744	1.00	89.00	O
ATOM	299	N	VAL	A	256	38.396	−7.364	39.423	1.00	87.76	N
ATOM	300	CA	VAL	A	256	37.652	−7.123	38.175	1.00	87.33	C
ATOM	302	CB	VAL	A	256	38.621	−6.876	36.959	1.00	87.32	C
ATOM	304	CG1	VAL	A	256	37.863	−6.540	35.667	1.00	87.04	C
ATOM	308	CG2	VAL	A	256	39.615	−5.743	37.249	1.00	86.86	C
ATOM	312	C	VAL	A	256	36.752	−8.334	37.881	1.00	86.63	C
ATOM	313	O	VAL	A	256	37.148	−9.481	38.100	1.00	86.42	O
ATOM	315	N	TYR	A	257	35.541	−8.060	37.392	1.00	85.89	N
ATOM	316	CA	TYR	A	257	34.536	−9.087	37.115	1.00	85.28	C
ATOM	318	CB	TYR	A	257	33.411	−9.068	38.168	1.00	85.83	C
ATOM	321	CG	TYR	A	257	33.876	−9.525	39.535	1.00	86.28	C
ATOM	322	CD1	TYR	A	257	34.611	−8.663	40.364	1.00	86.91	C
ATOM	324	CE1	TYR	A	257	35.091	−9.076	41.611	1.00	87.58	C
ATOM	326	CZ	TYR	A	257	34.823	−10.362	42.064	1.00	87.23	C
ATOM	327	OH	TYR	A	257	35.297	−10.728	43.303	1.00	86.48	O
ATOM	329	CE2	TYR	A	257	34.085	−11.248	41.263	1.00	86.98	C
ATOM	331	CD2	TYR	A	257	33.617	−10.821	39.994	1.00	86.43	C
ATOM	333	C	TYR	A	257	33.940	−8.833	35.766	1.00	84.40	C
ATOM	334	O	TYR	A	257	33.750	−7.674	35.395	1.00	84.03	O
ATOM	336	N	GLU	A	258	33.634	−9.906	35.034	1.00	83.48	N
ATOM	337	CA	GLU	A	258	32.751	−9.785	33.867	1.00	82.83	C
ATOM	339	CB	GLU	A	258	32.700	−11.069	33.033	1.00	82.76	C
ATOM	342	CG	GLU	A	258	32.002	−10.883	31.689	1.00	83.06	C
ATOM	345	CD	GLU	A	258	31.950	−12.151	30.854	1.00	83.34	C
ATOM	346	OE1	GLU	A	258	32.996	−12.810	30.663	1.00	83.83	O
ATOM	347	OE2	GLU	A	258	30.856	−12.489	30.358	1.00	85.42	O
ATOM	348	C	GLU	A	258	31.345	−9.428	34.381	1.00	82.52	C
ATOM	349	O	GLU	A	258	30.874	−10.022	35.357	1.00	82.83	O
ATOM	351	N	GLY	A	259	30.712	−8.445	33.737	1.00	81.70	N
ATOM	352	CA	GLY	A	259	29.334	−8.023	34.026	1.00	80.99	C
ATOM	355	C	GLY	A	259	28.494	−7.888	32.756	1.00	79.87	C
ATOM	356	O	GLY	A	259	29.026	−7.932	31.638	1.00	79.33	O
ATOM	358	N	VAL	A	260	27.173	−7.756	32.955	1.00	78.85	N
ATOM	359	CA	VAL	A	260	26.187	−7.545	31.884	1.00	77.72	C
ATOM	361	CB	VAL	A	260	25.367	−8.820	31.548	1.00	77.27	C
ATOM	363	CG1	VAL	A	260	24.669	−8.654	30.210	1.00	76.96	C
ATOM	367	CG2	VAL	A	260	26.243	−10.045	31.472	1.00	77.81	C
ATOM	371	C	VAL	A	260	25.234	−6.401	32.272	1.00	77.02	C
ATOM	372	O	VAL	A	260	24.499	−6.525	33.253	1.00	76.86	O
ATOM	374	N	TRP	A	261	25.257	−5.313	31.493	1.00	76.10	N
ATOM	375	CA	TRP	A	261	24.374	−4.174	31.686	1.00	75.92	C
ATOM	377	CB	TRP	A	261	25.015	−2.881	31.122	1.00	75.41	C
ATOM	380	CG	TRP	A	261	24.434	−1.571	31.658	1.00	75.36	C
ATOM	381	CD1	TRP	A	261	23.142	−1.352	32.059	1.00	75.54	C
ATOM	383	NE1	TRP	A	261	22.975	−0.049	32.472	1.00	75.59	N
ATOM	385	CE2	TRP	A	261	24.158	0.626	32.328	1.00	74.96	C
ATOM	386	CD2	TRP	A	261	25.107	−0.296	31.810	1.00	75.43	C
ATOM	387	CE3	TRP	A	261	26.422	0.156	31.592	1.00	74.99	C
ATOM	389	CZ3	TRP	A	261	26.738	1.512	31.884	1.00	74.65	C
ATOM	391	CH2	TRP	A	261	25.759	2.393	32.383	1.00	74.88	C
ATOM	393	CZ2	TRP	A	261	24.473	1.973	32.614	1.00	74.58	C
ATOM	395	C	TRP	A	261	23.016	−4.568	31.026	1.00	76.27	C
ATOM	396	O	TRP	A	261	22.785	−4.309	29.835	1.00	76.64	O
ATOM	398	N	LYS	A	262	22.156	−5.227	31.827	1.00	76.14	N
ATOM	399	CA	LYS	A	262	20.798	−5.733	31.448	1.00	75.87	C
ATOM	401	CB	LYS	A	262	19.889	−5.798	32.700	1.00	75.99	C
ATOM	404	CG	LYS	A	262	20.218	−6.892	33.729	1.00	75.98	C
ATOM	407	CD	LYS	A	262	19.696	−6.545	35.141	1.00	75.65	C
ATOM	410	CE	LYS	A	262	20.231	−7.530	36.181	1.00	75.98	C
ATOM	413	NZ	LYS	A	262	19.984	−7.153	37.603	1.00	75.85	N
ATOM	417	C	LYS	A	262	20.056	−4.909	30.379	1.00	75.79	C
ATOM	418	O	LYS	A	262	19.639	−5.440	29.336	1.00	75.56	O
ATOM	420	N	LYS	A	263	19.927	−3.613	30.683	1.00	75.60	N
ATOM	421	CA	LYS	A	263	19.263	−2.569	29.857	1.00	75.28	C
ATOM	423	CB	LYS	A	263	19.536	−1.201	30.545	1.00	75.29	C
ATOM	426	CG	LYS	A	263	19.048	0.072	29.892	1.00	75.41	C
ATOM	429	CD	LYS	A	263	19.257	1.300	30.841	1.00	74.82	C
ATOM	432	CE	LYS	A	263	18.101	1.534	31.815	1.00	74.33	C
ATOM	435	NZ	LYS	A	263	17.792	2.983	32.047	1.00	72.65	N
ATOM	439	C	LYS	A	263	19.676	−2.563	28.363	1.00	75.05	C
ATOM	440	O	LYS	A	263	18.827	−2.439	27.489	1.00	74.92	O
ATOM	442	N	TYR	A	264	20.972	−2.757	28.098	1.00	75.05	N
ATOM	443	CA	TYR	A	264	21.581	−2.629	26.759	1.00	74.80	C
ATOM	445	CB	TYR	A	264	22.679	−1.564	26.808	1.00	74.92	C
ATOM	448	CG	TYR	A	264	22.337	−0.270	27.497	1.00	74.94	C
ATOM	449	CD1	TYR	A	264	22.498	−0.123	28.867	1.00	75.62	C
ATOM	451	CE1	TYR	A	264	22.220	1.096	29.503	1.00	75.76	C
ATOM	453	CZ	TYR	A	264	21.798	2.176	28.771	1.00	75.40	C
ATOM	454	OH	TYR	A	264	21.539	3.345	29.430	1.00	75.16	O
ATOM	456	CE2	TYR	A	264	21.657	2.070	27.402	1.00	75.92	C
ATOM	458	CD2	TYR	A	264	21.937	0.840	26.770	1.00	75.74	C
ATOM	460	C	TYR	A	264	22.211	−3.932	26.212	1.00	74.67	C
ATOM	461	O	TYR	A	264	23.180	−3.877	25.434	1.00	74.39	O
ATOM	463	N	SER	A	265	21.673	−5.087	26.627	1.00	74.64	N
ATOM	464	CA	SER	A	265	22.172	−6.457	26.279	1.00	74.05	C
ATOM	466	CB	SER	A	265	21.518	−6.904	24.950	1.00	74.19	C
ATOM	469	OG	SER	A	265	21.420	−8.318	24.842	1.00	74.38	O
ATOM	471	C	SER	A	265	23.721	−6.661	26.262	1.00	73.43	C
ATOM	472	O	SER	A	265	24.234	−7.570	25.607	1.00	73.19	O
ATOM	474	N	LEU	A	266	24.430	−5.850	27.051	1.00	72.71	N
ATOM	475	CA	LEU	A	266	25.854	−5.506	26.815	1.00	72.45	C
ATOM	477	CB	LEU	A	266	26.016	−3.971	26.872	1.00	72.46	C
ATOM	480	CG	LEU	A	266	27.398	−3.319	26.983	1.00	72.21	C
ATOM	482	CD1	LEU	A	266	28.158	−3.552	25.679	1.00	71.84	C
ATOM	486	CD2	LEU	A	266	27.239	−1.836	27.293	1.00	72.67	C
ATOM	490	C	LEU	A	266	26.793	−6.096	27.849	1.00	71.24	C
ATOM	491	O	LEU	A	266	26.587	−5.832	29.031	1.00	71.07	O
ATOM	493	N	THR	A	267	27.846	−6.804	27.413	1.00	69.96	N
ATOM	494	CA	THR	A	267	28.921	−7.217	28.317	1.00	69.27	C
ATOM	496	CB	THR	A	267	29.662	−8.485	27.811	1.00	69.35	C
ATOM	498	OG1	THR	A	267	28.791	−9.614	27.913	1.00	68.85	O
ATOM	500	CG2	THR	A	267	30.805	−8.923	28.752	1.00	69.65	C
ATOM	504	C	THR	A	267	29.892	−6.051	28.623	1.00	69.12	C
ATOM	505	O	THR	A	267	30.276	−5.267	27.741	1.00	68.18	O
ATOM	507	N	VAL	A	268	30.277	−5.987	29.902	1.00	69.34	N
ATOM	508	CA	VAL	A	268	31.144	−4.951	30.489	1.00	69.17	C
ATOM	510	CB	VAL	A	268	30.334	−3.902	31.288	1.00	68.79	C
ATOM	512	CG1	VAL	A	268	29.660	−2.936	30.364	1.00	68.30	C
ATOM	516	CG2	VAL	A	268	29.309	−4.558	32.208	1.00	68.29	C
ATOM	520	C	VAL	A	268	32.161	−5.572	31.443	1.00	69.57	C
ATOM	521	O	VAL	A	268	32.005	−6.699	31.894	1.00	69.27	O
ATOM	523	N	ALA	A	269	33.216	−4.829	31.724	1.00	70.81	N
ATOM	524	CA	ALA	A	269	34.108	−5.141	32.849	1.00	71.81	C
ATOM	526	CB	ALA	A	269	35.551	−4.853	32.484	1.00	71.50	C
ATOM	530	C	ALA	A	269	33.658	−4.259	34.006	1.00	72.55	C
ATOM	531	O	ALA	A	269	33.377	−3.086	33.789	1.00	72.88	O
ATOM	533	N	VAL	A	270	33.551	−4.821	35.209	1.00	73.46	N
ATOM	534	CA	VAL	A	270	33.347	−4.030	36.420	1.00	74.63	C
ATOM	536	CB	VAL	A	270	31.934	−4.263	37.049	1.00	74.51	C
ATOM	538	CG1	VAL	A	270	31.677	−3.297	38.215	1.00	74.25	C
ATOM	542	CG2	VAL	A	270	30.826	−4.095	35.996	1.00	74.34	C
ATOM	546	C	VAL	A	270	34.499	−4.312	37.414	1.00	75.53	C
ATOM	547	O	VAL	A	270	34.587	−5.432	37.967	1.00	75.75	O
ATOM	549	N	LYS	A	271	35.392	−3.315	37.589	1.00	76.54	N
ATOM	550	CA	LYS	A	271	36.379	−3.289	38.691	1.00	76.71	C
ATOM	552	CB	LYS	A	271	37.650	−2.423	38.405	1.00	77.09	C
ATOM	555	CG	LYS	A	271	38.873	−2.742	39.415	1.00	77.54	C
ATOM	558	CD	LYS	A	271	40.361	−2.133	39.146	1.00	77.33	C
ATOM	561	CE	LYS	A	271	41.168	−1.921	40.537	1.00	76.92	C
ATOM	564	NZ	LYS	A	271	42.674	−2.166	40.628	1.00	74.71	N
ATOM	568	C	LYS	A	271	35.653	−2.833	39.955	1.00	77.26	C
ATOM	569	O	LYS	A	271	35.034	−1.781	39.974	1.00	76.34	O
ATOM	571	N	THR	A	272	35.730	−3.670	40.985	1.00	78.63	N
ATOM	572	CA	THR	A	272	35.006	−3.516	42.236	1.00	80.00	C
ATOM	574	CB	THR	A	272	34.149	−4.817	42.470	1.00	79.55	C
ATOM	576	OG1	THR	A	272	33.042	−4.529	43.315	1.00	79.43	O
ATOM	578	CG2	THR	A	272	34.891	−5.928	43.203	1.00	79.48	C
ATOM	582	C	THR	A	272	35.991	−3.196	43.382	1.00	80.67	C
ATOM	583	O	THR	A	272	37.211	−3.413	43.241	1.00	80.64	O
ATOM	585	N	LEU	A	273	35.459	−2.668	44.490	1.00	81.70	N
ATOM	586	CA	LEU	A	273	36.216	−2.502	45.754	1.00	82.45	C
ATOM	588	CB	LEU	A	273	36.662	−1.051	45.952	1.00	82.31	C
ATOM	591	CG	LEU	A	273	37.804	−0.832	46.971	1.00	81.89	C
ATOM	593	CD1	LEU	A	273	39.194	−1.166	46.387	1.00	81.15	C
ATOM	597	CD2	LEU	A	273	37.793	0.592	47.501	1.00	81.96	C
ATOM	601	C	LEU	A	273	35.398	−2.958	46.968	1.00	83.39	C
ATOM	602	O	LEU	A	273	34.313	−2.435	47.214	1.00	83.53	O
ATOM	604	N	LYS	A	274	35.938	−3.915	47.731	1.00	84.79	N
ATOM	605	CA	LYS	A	274	35.287	−4.441	48.951	1.00	85.58	C
ATOM	607	CB	LYS	A	274	36.033	−5.677	49.490	1.00	85.72	C
ATOM	610	CG	LYS	A	274	36.039	−6.904	48.557	1.00	85.83	C
ATOM	613	CD	LYS	A	274	36.906	−8.036	49.155	1.00	85.99	C
ATOM	616	CE	LYS	A	274	37.466	−9.011	48.113	1.00	86.03	C
ATOM	619	NZ	LYS	A	274	38.640	−9.761	48.665	1.00	85.15	N
ATOM	623	C	LYS	A	274	35.210	−3.362	50.058	1.00	86.26	C
ATOM	624	O	LYS	A	274	36.247	−2.983	50.620	1.00	86.20	O
ATOM	626	N	GLU	A	275	33.981	−2.893	50.322	1.00	86.92	N
ATOM	627	CA	GLU	A	275	33.599	−1.857	51.336	1.00	87.61	C
ATOM	629	CB	GLU	A	275	32.345	−2.327	52.135	1.00	87.78	C
ATOM	632	CG	GLU	A	275	32.345	−3.772	52.662	1.00	88.17	C
ATOM	635	CD	GLU	A	275	30.958	−4.427	52.683	1.00	87.94	C
ATOM	636	OE1	GLU	A	275	30.216	−4.329	51.676	1.00	87.74	O
ATOM	637	OE2	GLU	A	275	30.611	−5.065	53.704	1.00	88.21	O
ATOM	638	C	GLU	A	275	34.635	−1.203	52.299	1.00	88.06	C
ATOM	639	O	GLU	A	275	34.982	−0.026	52.111	1.00	88.02	O
ATOM	641	N	ASP	A	276	35.098	−1.959	53.306	1.00	88.51	N
ATOM	642	CA	ASP	A	276	35.996	−1.429	54.363	1.00	88.89	C
ATOM	644	CB	ASP	A	276	36.169	−2.432	55.524	1.00	88.64	C
ATOM	647	CG	ASP	A	276	35.189	−2.193	56.648	1.00	88.36	C
ATOM	648	OD1	ASP	A	276	33.987	−2.103	56.347	1.00	88.75	O
ATOM	649	OD2	ASP	A	276	35.519	−2.081	57.854	1.00	86.74	O
ATOM	650	C	ASP	A	276	37.385	−0.997	53.876	1.00	89.58	C
ATOM	651	O	ASP	A	276	37.790	0.147	54.140	1.00	89.49	O
ATOM	653	N	THR	A	277	38.080	−1.910	53.171	1.00	90.48	N
ATOM	654	CA	THR	A	277	39.526	−1.776	52.795	1.00	90.67	C
ATOM	656	CB	THR	A	277	40.045	−3.008	51.970	1.00	90.64	C
ATOM	658	OG1	THR	A	277	39.129	−3.335	50.916	1.00	89.62	O
ATOM	660	CG2	THR	A	277	40.110	−4.275	52.855	1.00	90.49	C
ATOM	664	C	THR	A	277	39.872	−0.465	52.059	1.00	91.07	C
ATOM	665	O	THR	A	277	39.463	−0.271	50.911	1.00	90.51	O
ATOM	667	N	MET	A	278	40.638	0.406	52.750	1.00	91.74	N
ATOM	668	CA	MET	A	278	40.877	1.815	52.356	1.00	91.84	C
ATOM	670	CB	MET	A	278	41.070	2.741	53.585	1.00	91.87	C
ATOM	673	CO	MET	A	278	39.814	2.976	54.461	1.00	91.93	C
ATOM	676	SD	MET	A	278	40.170	3.936	55.999	1.00	92.15	S
ATOM	677	CE	MET	A	278	38.531	4.195	56.708	1.00	91.95	C
ATOM	681	C	MET	A	278	42.038	1.973	51.340	1.00	92.19	C
ATOM	682	O	MET	A	278	43.107	2.525	51.641	1.00	92.28	O
ATOM	684	N	GLU	A	279	41.791	1.443	50.137	1.00	92.25	N
ATOM	685	CA	GLU	A	279	42.265	2.042	48.896	1.00	91.93	C
ATOM	687	CB	GLU	A	279	42.763	0.956	47.919	1.00	92.14	C
ATOM	690	CG	GLU	A	279	43.976	0.161	48.419	1.00	92.21	C
ATOM	693	CD	GLU	A	279	43.608	−1.147	49.106	1.00	91.94	C
ATOM	694	OE1	GLU	A	279	43.319	−1.121	50.326	1.00	91.54	O
ATOM	695	OE2	GLU	A	279	43.621	−2.199	48.422	1.00	90.77	O
ATOM	696	C	GLU	A	279	41.104	2.865	48.296	1.00	91.66	C
ATOM	697	O	GLU	A	279	41.034	3.025	47.082	1.00	91.72	O
ATOM	699	N	VAL	A	280	40.228	3.409	49.158	1.00	91.38	N
ATOM	700	CA	VAL	A	280	39.082	4.262	48.790	1.00	91.44	C
ATOM	702	CB	VAL	A	280	38.187	4.573	50.059	1.00	91.62	C
ATOM	704	CG1	VAL	A	280	37.117	5.649	49.795	1.00	92.06	C
ATOM	708	CG2	VAL	A	280	37.513	3.299	50.569	1.00	92.20	C
ATOM	712	C	VAL	A	280	39.610	5.565	48.157	1.00	90.87	C
ATOM	713	O	VAL	A	280	39.104	6.025	47.127	1.00	90.63	O
ATOM	715	N	GLU	A	281	40.623	6.135	48.813	1.00	90.12	N
ATOM	716	CA	GLU	A	281	41.472	7.205	48.284	1.00	89.59	C
ATOM	718	CB	GLU	A	281	42.694	7.408	49.229	1.00	89.64	C
ATOM	721	CG	GLU	A	281	43.697	8.487	48.845	1.00	89.59	C
ATOM	724	CD	GLU	A	281	43.055	9.851	48.741	1.00	89.08	C
ATOM	725	OE1	GLU	A	281	42.905	10.507	49.789	1.00	89.29	O
ATOM	726	OE2	GLU	A	281	42.691	10.258	47.615	1.00	88.22	O
ATOM	727	C	GLU	A	281	41.937	6.866	46.873	1.00	88.92	C
ATOM	728	O	GLU	A	281	41.589	7.555	45.918	1.00	88.87	O
ATOM	730	N	GLU	A	282	42.658	5.756	46.765	1.00	88.39	N
ATOM	731	CA	GLU	A	282	43.383	5.368	45.542	1.00	87.76	C
ATOM	733	CB	GLU	A	282	44.440	4.297	45.922	1.00	88.40	C
ATOM	736	CG	GLU	A	282	45.480	3.945	44.861	1.00	89.10	C
ATOM	739	CD	GLU	A	282	46.223	5.161	44.323	1.00	90.47	C
ATOM	740	OE1	GLU	A	282	46.624	6.032	45.149	1.00	90.12	O
ATOM	741	OE2	GLU	A	282	46.384	5.238	43.079	1.00	90.36	O
ATOM	742	C	GLU	A	282	42.514	4.887	44.344	1.00	87.08	C
ATOM	743	O	GLU	A	282	42.950	4.992	43.194	1.00	86.60	O
ATOM	745	N	PHE	A	283	41.302	4.393	44.637	1.00	86.28	N
ATOM	746	CA	PHE	A	283	40.321	3.833	43.663	1.00	85.78	C
ATOM	748	CB	PHE	A	283	39.465	2.796	44.414	1.00	85.60	C
ATOM	751	CG	PHE	A	283	38.454	2.043	43.576	1.00	86.05	C
ATOM	752	CD1	PHE	A	283	37.164	2.571	43.359	1.00	85.61	C
ATOM	754	CE1	PHE	A	283	36.204	1.846	42.620	1.00	85.32	C
ATOM	756	CZ	PHE	A	283	36.520	0.571	42.123	1.00	85.38	C
ATOM	758	CE2	PHE	A	283	37.792	0.017	42.364	1.00	85.62	C
ATOM	760	CD2	PHE	A	283	38.747	0.746	43.100	1.00	85.65	C
ATOM	762	C	PHE	A	283	39.415	4.906	43.026	1.00	85.17	C
ATOM	763	O	PHE	A	283	39.115	4.836	41.837	1.00	85.20	O
ATOM	765	N	LEU	A	284	38.935	5.841	43.848	1.00	84.54	N
ATOM	766	CA	LEU	A	284	38.289	7.082	43.383	1.00	84.07	C
ATOM	768	CB	LEU	A	284	37.799	7.976	44.553	1.00	84.23	C
ATOM	771	CG	LEU	A	284	36.345	7.834	45.041	1.00	84.42	C
ATOM	773	CD1	LEU	A	284	36.217	6.760	46.133	1.00	84.04	C
ATOM	777	CD2	LEU	A	284	35.792	9.191	45.545	1.00	84.18	C
ATOM	781	C	LEU	A	284	39.204	7.937	42.510	1.00	83.56	C
ATOM	782	O	LEU	A	284	38.707	8.614	41.602	1.00	83.85	O
ATOM	784	N	LYS	A	285	40.506	7.962	42.826	1.00	82.50	N
ATOM	785	CA	LYS	A	285	41.501	8.664	41.988	1.00	81.94	C
ATOM	787	CB	LYS	A	285	42.900	8.725	42.637	1.00	81.87	C
ATOM	790	CG	LYS	A	285	43.101	9.916	43.589	1.00	83.18	C
ATOM	793	CD	LYS	A	285	43.577	11.243	42.886	1.00	84.29	C
ATOM	796	CE	LYS	A	285	42.473	12.020	42.103	1.00	84.41	C
ATOM	799	NZ	LYS	A	285	42.376	11.636	40.647	1.00	83.92	N
ATOM	803	C	LYS	A	285	41.590	8.055	40.585	1.00	80.49	C
ATOM	804	O	LYS	A	285	41.631	8.799	39.597	1.00	80.40	O
ATOM	806	N	GLU	A	286	41.590	6.717	40.509	1.00	78.57	N
ATOM	807	CA	GLU	A	286	41.571	6.025	39.229	1.00	76.92	C
ATOM	809	CB	GLU	A	286	41.609	4.509	39.390	1.00	76.80	C
ATOM	812	CG	GLU	A	286	42.068	3.853	38.111	1.00	76.55	C
ATOM	815	CD	GLU	A	286	41.897	2.357	38.076	1.00	77.14	C
ATOM	816	OE1	GLU	A	286	41.944	1.694	39.145	1.00	74.02	O
ATOM	817	OE2	GLU	A	286	41.741	1.852	36.930	1.00	79.62	O
ATOM	818	C	GLU	A	286	40.342	6.431	38.427	1.00	75.69	C
ATOM	819	O	GLU	A	286	40.471	6.886	37.293	1.00	75.74	O
ATOM	821	N	ALA	A	287	39.170	6.288	39.034	1.00	74.28	N
ATOM	822	CA	ALA	A	287	37.907	6.733	38.438	1.00	73.38	C
ATOM	824	CB	ALA	A	287	36.790	6.571	39.422	1.00	73.37	C
ATOM	828	C	ALA	A	287	37.952	8.184	37.934	1.00	72.87	C
ATOM	829	O	ALA	A	287	37.603	8.441	36.796	1.00	72.37	O
ATOM	831	N	ALA	A	288	38.419	9.104	38.775	1.00	72.65	N
ATOM	832	CA	ALA	A	288	38.531	10.538	38.428	1.00	72.79	C
ATOM	834	CB	ALA	A	288	39.084	11.327	39.614	1.00	72.97	C
ATOM	838	C	ALA	A	288	39.409	10.792	37.203	1.00	72.62	C
ATOM	839	O	ALA	A	288	39.117	11.664	36.387	1.00	73.00	O
ATOM	841	N	VAL	A	289	40.493	10.031	37.102	1.00	72.27	N
ATOM	842	CA	VAL	A	289	41.428	10.123	35.987	1.00	71.86	C
ATOM	844	CB	VAL	A	289	42.725	9.265	36.267	1.00	71.83	C
ATOM	846	CG1	VAL	A	289	43.555	9.016	35.004	1.00	72.53	C
ATOM	850	CG2	VAL	A	289	43.573	9.934	37.310	1.00	71.78	C
ATOM	854	C	VAL	A	289	40.698	9.693	34.707	1.00	71.68	C
ATOM	855	O	VAL	A	289	40.582	10.489	33.769	1.00	71.31	O
ATOM	857	N	MET	A	290	40.194	8.451	34.716	1.00	71.41	N
ATOM	858	CA	MET	A	290	39.414	7.866	33.607	1.00	71.13	C
ATOM	860	CB	MET	A	290	38.777	6.552	34.027	1.00	70.54	C
ATOM	863	CG	MET	A	290	39.772	5.449	34.104	1.00	70.96	C
ATOM	866	SD	MET	A	290	39.063	3.871	33.716	1.00	71.69	S
ATOM	867	CE	MET	A	290	39.144	3.123	35.325	1.00	72.91	C
ATOM	871	C	MET	A	290	38.329	8.765	33.020	1.00	71.20	C
ATOM	872	O	MET	A	290	38.183	8.778	31.804	1.00	71.87	O
ATOM	874	N	LYS	A	291	37.591	9.492	33.878	1.00	70.87	N
ATOM	875	CA	LYS	A	291	36.621	10.520	33.455	1.00	70.54	C
ATOM	877	CB	LYS	A	291	36.052	11.257	34.662	1.00	70.45	C
ATOM	880	CG	LYS	A	291	35.052	10.482	35.497	1.00	70.39	C
ATOM	883	CD	LYS	A	291	34.522	11.383	36.630	1.00	70.23	C
ATOM	886	CE	LYS	A	291	33.411	10.743	37.460	1.00	70.38	C
ATOM	889	NZ	LYS	A	291	33.857	10.291	38.810	1.00	70.64	N
ATOM	893	C	LYS	A	291	37.189	11.573	32.493	1.00	70.72	C
ATOM	894	O	LYS	A	291	36.508	11.949	31.557	1.00	71.37	O
ATOM	896	N	GLU	A	292	38.422	12.027	32.740	1.00	70.66	N
ATOM	897	CA	GLU	A	292	39.121	13.061	31.929	1.00	70.19	C
ATOM	899	CB	GLU	A	292	40.274	13.716	32.756	1.00	71.34	C
ATOM	902	CG	GLU	A	292	39.844	14.600	33.924	1.00	72.52	C
ATOM	905	CD	GLU	A	292	38.824	15.634	33.489	1.00	76.37	C
ATOM	906	OE1	GLU	A	292	39.064	16.293	32.443	1.00	78.86	O
ATOM	907	OE2	GLU	A	292	37.759	15.753	34.150	1.00	79.36	O
ATOM	908	C	GLU	A	292	39.726	12.617	30.602	1.00	69.45	C
ATOM	909	O	GLU	A	292	40.089	13.483	29.798	1.00	68.68	O
ATOM	911	N	ILE	A	293	39.847	11.297	30.391	1.00	68.93	N
ATOM	912	CA	ILE	A	293	40.522	10.703	29.207	1.00	68.37	C
ATOM	914	CB	ILE	A	293	41.723	9.744	29.585	1.00	68.22	C
ATOM	916	CG1	ILE	A	293	41.284	8.561	30.478	1.00	68.00	C
ATOM	919	CD1	ILE	A	293	42.408	7.534	30.814	1.00	68.00	C
ATOM	923	CG2	ILE	A	293	42.904	10.551	30.182	1.00	67.58	C
ATOM	927	C	ILE	A	293	39.533	9.946	28.344	1.00	67.75	C
ATOM	928	O	ILE	A	293	38.601	9.331	28.868	1.00	67.66	O
ATOM	930	N	LYS	A	294	39.764	9.984	27.027	1.00	67.16	N
ATOM	931	CA	LYS	A	294	38.852	9.416	26.018	1.00	66.81	C
ATOM	933	CB	LYS	A	294	37.611	10.318	25.852	1.00	66.74	C
ATOM	936	CG	LYS	A	294	36.504	9.737	25.024	1.00	66.80	C
ATOM	939	CD	LYS	A	294	35.379	10.722	24.811	1.00	67.87	C
ATOM	942	CE	LYS	A	294	34.162	10.028	24.184	1.00	69.17	C
ATOM	945	NZ	LYS	A	294	33.543	9.072	25.184	1.00	70.26	N
ATOM	949	C	LYS	A	294	39.609	9.331	24.693	1.00	66.21	C
ATOM	950	O	LYS	A	294	40.126	10.335	24.220	1.00	66.76	O
ATOM	952	N	HIS	A	295	39.684	8.140	24.111	1.00	65.16	N
ATOM	953	CA	HIS	A	295	40.510	7.880	22.920	1.00	64.11	C
ATOM	955	CB	HIS	A	295	41.991	8.048	23.269	1.00	63.82	C
ATOM	958	CG	HIS	A	295	42.905	7.962	22.100	1.00	63.30	C
ATOM	959	ND1	HIS	A	295	43.278	6.768	21.535	1.00	62.33	N
ATOM	961	CE1	HIS	A	295	44.095	6.996	20.528	1.00	62.75	C
ATOM	963	NE2	HIS	A	295	44.282	8.300	20.434	1.00	62.37	N
ATOM	965	CD2	HIS	A	295	43.547	8.925	21.404	1.00	62.78	C
ATOM	967	C	HIS	A	295	40.218	6.427	22.498	1.00	64.01	C
ATOM	968	O	HIS	A	295	40.043	5.565	23.381	1.00	64.08	O
ATOM	970	N	PRO	A	296	40.154	6.111	21.201	1.00	63.65	N
ATOM	971	CA	PRO	A	296	39.740	4.734	20.807	1.00	63.45	C
ATOM	973	CB	PRO	A	296	39.514	4.862	19.300	1.00	63.16	C
ATOM	976	CG	PRO	A	296	40.433	5.970	18.907	1.00	63.20	C
ATOM	979	CD	PRO	A	296	40.392	6.960	20.015	1.00	63.29	C
ATOM	982	C	PRO	A	296	40.720	3.583	21.158	1.00	63.15	C
ATOM	983	O	PRO	A	296	40.373	2.415	20.965	1.00	62.79	O
ATOM	984	N	ASN	A	297	41.911	3.943	21.665	1.00	63.33	N
ATOM	985	CA	ASN	A	297	42.987	3.049	22.153	1.00	62.79	C
ATOM	987	CB	ASN	A	297	44.248	3.329	21.344	1.00	62.18	C
ATOM	990	CG	ASN	A	297	44.099	2.982	19.886	1.00	61.52	C
ATOM	991	OD1	ASN	A	297	44.534	3.737	19.023	1.00	61.60	O
ATOM	992	ND2	ASN	A	297	43.518	1.830	19.601	1.00	59.64	N
ATOM	995	C	ASN	A	297	43.273	3.197	23.674	1.00	62.80	C
ATOM	996	O	ASN	A	297	44.376	2.858	24.149	1.00	62.69	O
ATOM	998	N	LEU	A	298	42.291	3.720	24.418	1.00	62.50	N
ATOM	999	CA	LEU	A	298	42.278	3.691	25.869	1.00	63.06	C
ATOM	1001	CB	LEU	A	298	42.342	5.106	26.432	1.00	63.37	C
ATOM	1004	CG	LEU	A	298	43.577	5.945	26.111	1.00	64.23	C
ATOM	1006	CD1	LEU	A	298	43.403	7.348	26.624	1.00	64.50	C
ATOM	1010	CD2	LEU	A	298	44.805	5.338	26.721	1.00	65.89	C
ATOM	1014	C	LEU	A	298	40.982	3.039	26.333	1.00	63.13	C
ATOM	1015	O	LEU	A	298	39.922	3.464	25.905	1.00	64.25	O
ATOM	1017	N	VAL	A	299	41.047	2.066	27.238	1.00	62.67	N
ATOM	1018	CA	VAL	A	299	39.845	1.394	27.732	1.00	62.56	C
ATOM	1020	CB	VAL	A	299	40.185	0.406	28.834	1.00	62.14	C
ATOM	1022	CG1	VAL	A	299	38.919	−0.124	29.535	1.00	62.99	C
ATOM	1026	CG2	VAL	A	299	40.955	−0.729	28.260	1.00	62.66	C
ATOM	1030	C	VAL	A	299	38.897	2.445	28.291	1.00	62.79	C
ATOM	1031	O	VAL	A	299	39.328	3.274	29.047	1.00	63.51	O
ATOM	1033	N	GLN	A	300	37.628	2.400	27.913	1.00	63.32	N
ATOM	1034	CA	GLN	A	300	36.685	3.500	28.127	1.00	63.63	C
ATOM	1036	CB	GLN	A	300	35.756	3.675	26.917	1.00	63.32	C
ATOM	1039	CG	GLN	A	300	34.685	4.816	27.034	1.00	63.33	C
ATOM	1042	CD	GLN	A	300	35.263	6.198	27.379	1.00	61.22	C
ATOM	1043	OE1	GLN	A	300	35.041	6.720	28.456	1.00	59.23	O
ATOM	1044	NE2	GLN	A	300	36.002	6.769	26.461	1.00	61.49	N
ATOM	1047	C	GLN	A	300	35.854	3.259	29.381	1.00	64.19	C
ATOM	1048	O	GLN	A	300	35.225	2.217	29.514	1.00	63.96	O
ATOM	1050	N	LEU	A	301	35.866	4.245	30.283	1.00	65.01	N
ATOM	1051	CA	LEU	A	301	34.946	4.310	31.400	1.00	65.66	C
ATOM	1053	CB	LEU	A	301	35.311	5.484	32.307	1.00	65.87	C
ATOM	1056	CG	LEU	A	301	34.454	5.771	33.555	1.00	65.55	C
ATOM	1058	CD1	LEU	A	301	34.585	4.634	34.534	1.00	64.53	C
ATOM	1062	CD2	LEU	A	301	34.850	7.107	34.212	1.00	65.68	C
ATOM	1066	C	LEU	A	301	33.522	4.512	30.865	1.00	66.65	C
ATOM	1067	O	LEU	A	301	33.227	5.528	30.210	1.00	66.88	O
ATOM	1069	N	LEU	A	302	32.648	3.545	31.142	1.00	67.04	N
ATOM	1070	CA	LEU	A	302	31.225	3.652	30.801	1.00	66.76	C
ATOM	1072	CB	LEU	A	302	30.670	2.307	30.378	1.00	66.20	C
ATOM	1075	CG	LEU	A	302	31.392	1.728	29.156	1.00	65.50	C
ATOM	1077	CD1	LEU	A	302	30.845	0.348	28.924	1.00	66.48	C
ATOM	1081	CD2	LEU	A	302	31.259	2.583	27.887	1.00	64.32	C
ATOM	1085	C	LEU	A	302	30.433	4.220	31.959	1.00	67.32	C
ATOM	1086	O	LEU	A	302	29.543	5.030	31.731	1.00	67.57	O
ATOM	1088	N	GLY	A	303	30.753	3.822	33.193	1.00	68.14	N
ATOM	1089	CA	GLY	A	303	29.989	4.287	34.367	1.00	68.66	C
ATOM	1092	C	GLY	A	303	30.540	3.874	35.699	1.00	69.03	C
ATOM	1093	O	GLY	A	303	31.467	3.067	35.748	1.00	68.17	O
ATOM	1095	N	VAL	A	304	29.951	4.421	36.773	1.00	70.26	N
ATOM	1096	CA	VAL	A	304	30.425	4.182	38.163	1.00	71.13	C
ATOM	1098	CB	VAL	A	304	31.456	5.263	38.660	1.00	71.03	C
ATOM	1100	CG1	VAL	A	304	32.751	5.176	37.892	1.00	70.35	C
ATOM	1104	CG2	VAL	A	304	30.868	6.707	38.606	1.00	71.13	C
ATOM	1108	C	VAL	A	304	29.327	4.097	39.212	1.00	72.12	C
ATOM	1109	O	VAL	A	304	28.233	4.594	39.006	1.00	72.20	O
ATOM	1111	N	CYS	A	305	29.657	3.453	40.333	1.00	73.76	N
ATOM	1112	CA	CYS	A	305	28.875	3.495	41.584	1.00	75.38	C
ATOM	1114	CB	CYS	A	305	28.204	2.152	41.846	1.00	75.15	C
ATOM	1117	SG	CYS	A	305	27.535	1.430	40.364	1.00	74.26	S
ATOM	1119	C	CYS	A	305	29.812	3.879	42.751	1.00	76.29	C
ATOM	1120	O	CYS	A	305	30.569	3.036	43.257	1.00	76.41	O
ATOM	1122	N	THR	A	306	29.793	5.166	43.111	1.00	77.27	N
ATOM	1123	CA	THR	A	306	30.635	5.749	44.166	1.00	78.12	C
ATOM	1125	CB	THR	A	306	31.701	6.687	43.537	1.00	78.19	C
ATOM	1127	OG1	THR	A	306	31.067	7.781	42.862	1.00	78.61	O
ATOM	1129	CG2	THR	A	306	32.499	5.995	42.440	1.00	78.02	C
ATOM	1133	C	THR	A	306	29.858	6.517	45.260	1.00	79.18	C
ATOM	1134	O	THR	A	306	30.475	7.091	46.169	1.00	79.58	O
ATOM	1136	N	ARG	A	307	28.523	6.523	45.186	1.00	79.97	N
ATOM	1137	CA	ARG	A	307	27.679	7.102	46.232	1.00	80.18	C
ATOM	1139	CB	ARG	A	307	26.207	7.111	45.821	1.00	80.34	C
ATOM	1142	CG	ARG	A	307	25.892	7.891	44.601	1.00	80.53	C
ATOM	1145	CD	ARG	A	307	25.630	9.359	44.791	1.00	81.08	C
ATOM	1148	NE	ARG	A	307	25.410	9.968	43.468	1.00	81.40	N
ATOM	1150	CZ	ARG	A	307	24.657	11.040	43.188	1.00	81.22	C
ATOM	1151	NH1	ARG	A	307	23.980	11.714	44.133	1.00	80.50	N
ATOM	1154	NH2	ARG	A	307	24.577	11.439	41.912	1.00	81.42	N
ATOM	1157	C	ARG	A	307	27.811	6.237	47.477	1.00	81.10	C
ATOM	1158	O	ARG	A	307	28.081	6.752	48.565	1.00	81.00	O
ATOM	1160	N	GLU	A	308	27.655	4.921	47.268	1.00	81.86	N
ATOM	1161	CA	GLU	A	308	27.400	3.921	48.319	1.00	82.42	C
ATOM	1163	CB	GLU	A	308	25.889	3.538	48.324	1.00	82.41	C
ATOM	1166	CG	GLU	A	308	24.962	4.452	47.501	1.00	82.71	C
ATOM	1169	CD	GLU	A	308	23.480	4.117	47.591	1.00	83.00	C
ATOM	1170	OE1	GLU	A	308	22.850	4.336	48.665	1.00	82.97	O
ATOM	1171	OE2	GLU	A	308	22.935	3.661	46.554	1.00	83.49	O
ATOM	1172	C	GLU	A	308	28.238	2.668	48.003	1.00	82.54	C
ATOM	1173	O	GLU	A	308	28.139	2.185	46.882	1.00	83.35	O
ATOM	1175	N	PRO	A	309	29.070	2.146	48.916	1.00	82.70	N
ATOM	1176	CA	PRO	A	309	29.683	0.792	48.731	1.00	82.65	C
ATOM	1178	CB	PRO	A	309	30.504	0.595	50.015	1.00	82.72	C
ATOM	1181	CG	PRO	A	309	30.808	1.986	50.483	1.00	82.78	C
ATOM	1184	CD	PRO	A	309	29.594	2.807	50.125	1.00	82.73	C
ATOM	1187	C	PRO	A	309	28.692	−0.405	48.511	1.00	82.39	C
ATOM	1188	O	PRO	A	309	27.467	−0.191	48.577	1.00	82.22	O
ATOM	1189	N	PRO	A	310	29.193	−1.637	48.268	1.00	82.03	N
ATOM	1190	CA	PRO	A	310	30.388	−1.934	47.408	1.00	81.56	C
ATOM	1192	CB	PRO	A	310	30.121	−3.390	46.937	1.00	81.53	C
ATOM	1195	CG	PRO	A	310	28.660	−3.681	47.332	1.00	81.51	C
ATOM	1198	CD	PRO	A	310	28.452	−2.885	48.579	1.00	81.90	C
ATOM	1201	C	PRO	A	310	30.600	−1.034	46.184	1.00	81.28	C
ATOM	1202	O	PRO	A	310	29.702	−0.946	45.371	1.00	81.70	O
ATOM	1203	N	PHE	A	311	31.753	−0.368	46.071	1.00	80.84	N
ATOM	1204	CA	PHE	A	311	32.013	0.562	44.941	1.00	80.50	C
ATOM	1206	CB	PHE	A	311	33.229	1.468	45.215	1.00	81.26	C
ATOM	1209	CG	PHE	A	311	33.056	2.466	46.341	1.00	81.65	C
ATOM	1210	CD1	PHE	A	311	31.836	3.143	46.568	1.00	83.07	C
ATOM	1212	CE1	PHE	A	311	31.715	4.100	47.602	1.00	83.08	C
ATOM	1214	CZ	PHE	A	311	32.832	4.407	48.406	1.00	83.12	C
ATOM	1216	CE2	PHE	A	311	34.060	3.753	48.175	1.00	82.98	C
ATOM	1218	CD2	PHE	A	311	34.162	2.795	47.138	1.00	82.23	C
ATOM	1220	C	PHE	A	311	32.287	−0.165	43.616	1.00	80.01	C
ATOM	1221	O	PHE	A	311	32.975	−1.198	43.638	1.00	80.09	O
ATOM	1223	N	TYR	A	312	31.795	0.403	42.488	1.00	78.96	N
ATOM	1224	CA	TYR	A	312	31.973	−0.142	41.095	1.00	78.21	C
ATOM	1226	CB	TYR	A	312	30.616	−0.589	40.507	1.00	78.08	C
ATOM	1229	CG	TYR	A	312	29.934	−1.847	41.023	1.00	78.36	C
ATOM	1230	CD1	TYR	A	312	30.598	−2.783	41.846	1.00	78.53	C
ATOM	1232	CE1	TYR	A	312	29.947	−3.945	42.289	1.00	78.74	C
ATOM	1234	CZ	TYR	A	312	28.638	−4.204	41.898	1.00	77.96	C
ATOM	1235	OH	TYR	A	312	28.058	−5.353	42.365	1.00	78.24	O
ATOM	1237	CE2	TYR	A	312	27.955	−3.315	41.062	1.00	77.95	C
ATOM	1239	CD2	TYR	A	312	28.606	−2.141	40.626	1.00	77.80	C
ATOM	1241	C	TYR	A	312	32.536	0.870	40.066	1.00	76.60	C
ATOM	1242	O	TYR	A	312	31.951	1.915	39.887	1.00	76.21	O
ATOM	1244	N	ILE	A	313	33.637	0.542	39.388	1.00	75.47	N
ATOM	1245	CA	ILE	A	313	33.999	1.162	38.107	1.00	75.08	C
ATOM	1247	CB	ILE	A	313	35.494	1.490	38.011	1.00	74.66	C
ATOM	1249	CG1	ILE	A	313	35.833	2.686	38.885	1.00	75.43	C
ATOM	1252	CD1	ILE	A	313	37.380	2.834	39.177	1.00	76.05	C
ATOM	1256	CG2	ILE	A	313	35.898	1.837	36.568	1.00	74.63	C
ATOM	1260	C	ILE	A	313	33.605	0.182	36.993	1.00	74.76	C
ATOM	1261	O	ILE	A	313	34.070	−0.952	36.989	1.00	74.17	O
ATOM	1263	N	ILE	A	314	32.794	0.663	36.046	1.00	74.35	N
ATOM	1264	CA	ILE	A	314	32.342	−0.090	34.888	1.00	74.17	C
ATOM	1266	CB	ILE	A	314	30.817	0.072	34.688	1.00	74.31	C
ATOM	1268	CG1	ILE	A	314	30.070	−0.402	35.951	1.00	75.01	C
ATOM	1271	CD1	ILE	A	314	29.828	0.654	37.004	1.00	75.58	C
ATOM	1275	CG2	ILE	A	314	30.341	−0.698	33.433	1.00	73.68	C
ATOM	1279	C	ILE	A	314	33.085	0.455	33.678	1.00	73.98	C
ATOM	1280	O	ILE	A	314	33.120	1.672	33.468	1.00	74.80	O
ATOM	1282	N	THR	A	315	33.682	−0.437	32.894	1.00	73.15	N
ATOM	1283	CA	THR	A	315	34.313	−0.075	31.627	1.00	72.37	C
ATOM	1285	CB	THR	A	315	35.875	−0.050	31.729	1.00	72.39	C
ATOM	1287	OG1	THR	A	315	36.382	−1.367	31.919	1.00	71.53	O
ATOM	1289	CG2	THR	A	315	36.380	0.709	32.965	1.00	73.01	C
ATOM	1293	C	THR	A	315	33.888	−1.046	30.537	1.00	71.97	C
ATOM	1294	O	THR	A	315	33.270	−2.092	30.788	1.00	71.30	O
ATOM	1296	N	GLU	A	316	34.257	−0.674	29.314	1.00	71.64	N
ATOM	1297	CA	GLU	A	316	34.007	−1.484	28.146	1.00	71.30	C
ATOM	1299	CB	GLU	A	316	34.409	−0.758	26.863	1.00	71.42	C
ATOM	1302	CG	GLU	A	316	35.900	−0.586	26.636	1.00	72.45	C
ATOM	1305	CD	GLU	A	316	36.220	0.227	25.389	1.00	73.75	C
ATOM	1306	OE1	GLU	A	316	35.465	0.194	24.394	1.00	77.94	O
ATOM	1307	OE2	GLU	A	316	37.266	0.900	25.377	1.00	78.81	O
ATOM	1308	C	GLU	A	316	34.785	−2.751	28.297	1.00	69.81	C
ATOM	1309	O	GLU	A	316	35.849	−2.728	28.870	1.00	69.06	O
ATOM	1311	N	PHE	A	317	34.220	−3.835	27.785	1.00	69.21	N
ATOM	1312	CA	PHE	A	317	34.814	−5.163	27.839	1.00	68.70	C
ATOM	1314	CB	PHE	A	317	33.709	−6.190	27.990	1.00	68.39	C
ATOM	1317	CG	PHE	A	317	34.190	−7.569	28.187	1.00	67.49	C
ATOM	1318	CD1	PHE	A	317	34.851	−7.917	29.346	1.00	68.51	C
ATOM	1320	CE1	PHE	A	317	35.289	−9.243	29.550	1.00	69.21	C
ATOM	1322	CZ	PHE	A	317	35.053	−10.219	28.571	1.00	68.33	C
ATOM	1324	CE2	PHE	A	317	34.388	−9.865	27.409	1.00	68.37	C
ATOM	1326	CD2	PHE	A	317	33.950	−8.546	27.232	1.00	68.31	C
ATOM	1328	C	PHE	A	317	35.641	−5.420	26.552	1.00	69.05	C
ATOM	1329	O	PHE	A	317	35.269	−4.944	25.454	1.00	69.34	O
ATOM	1331	N	MET	A	318	36.751	−6.163	26.725	1.00	68.64	N
ATOM	1332	CA	MET	A	318	37.743	−6.510	25.687	1.00	67.80	C
ATOM	1334	CB	MET	A	318	39.069	−5.798	26.000	1.00	68.06	C
ATOM	1337	CG	MET	A	318	38.953	−4.289	26.156	1.00	68.55	C
ATOM	1340	SD	MET	A	318	38.679	−3.484	24.554	1.00	72.31	S
ATOM	1341	CE	MET	A	318	40.286	−3.408	23.859	1.00	70.76	C
ATOM	1345	C	MET	A	318	37.913	−8.050	25.700	1.00	66.94	C
ATOM	1346	O	MET	A	318	38.691	−8.601	26.476	1.00	66.14	O
ATOM	1348	N	THR	A	319	37.139	−8.718	24.848	1.00	66.49	N
ATOM	1349	CA	THR	A	319	36.995	−10.201	24.780	1.00	66.27	C
ATOM	1351	CB	THR	A	319	36.371	−10.589	23.427	1.00	66.14	C
ATOM	1353	OG1	THR	A	319	35.224	−9.776	23.196	1.00	65.99	O
ATOM	1355	CG2	THR	A	319	35.827	−12.049	23.414	1.00	66.55	C
ATOM	1359	C	THR	A	319	38.239	−11.055	24.938	1.00	65.58	C
ATOM	1360	O	THR	A	319	38.151	−12.131	25.529	1.00	65.37	O
ATOM	1362	N	TYR	A	320	39.362	−10.590	24.373	1.00	65.07	N
ATOM	1363	CA	TYR	A	320	40.620	−11.359	24.314	1.00	64.71	C
ATOM	1365	CB	TYR	A	320	41.219	−11.253	22.899	1.00	65.92	C
ATOM	1368	CG	TYR	A	320	40.383	−12.013	21.883	1.00	66.66	C
ATOM	1369	CD1	TYR	A	320	40.394	−13.422	21.855	1.00	68.48	C
ATOM	1371	CE1	TYR	A	320	39.590	−14.163	20.920	1.00	68.46	C
ATOM	1373	CZ	TYR	A	320	38.775	−13.475	20.026	1.00	68.18	C
ATOM	1374	OH	TYR	A	320	38.018	−14.199	19.137	1.00	67.52	O
ATOM	1376	CE2	TYR	A	320	38.748	−12.062	20.048	1.00	67.89	C
ATOM	1378	CD2	TYR	A	320	39.545	−11.342	20.975	1.00	67.64	C
ATOM	1380	C	TYR	A	320	41.651	−11.030	25.394	1.00	63.30	C
ATOM	1381	O	TYR	A	320	42.745	−11.600	25.401	1.00	63.09	O
ATOM	1383	N	GLY	A	321	41.304	−10.121	26.303	1.00	61.92	N
ATOM	1384	CA GLY	A	321	42.048	−9.926	27.541	1.00	60.67	C
ATOM	1387	C	GLY	A	321	43.422	−9.371	27.281	1.00	59.66	C
ATOM	1388	O	GLY	A	321	43.613	−8.684	26.262	1.00	59.76	O
ATOM	1390	N	ASN	A	322	44.380	−9.719	28.154	1.00	58.09	N
ATOM	1391	CA	ASN	A	322	45.676	−9.014	28.227	1.00	56.58	C
ATOM	1393	CB	ASN	A	322	46.337	−9.102	29.624	1.00	56.33	C
ATOM	1396	CG	ASN	A	322	47.110	−10.393	29.846	1.00	56.31	C
ATOM	1397	OD1	ASN	A	322	48.324	−10.402	29.781	1.00	57.93	O
ATOM	1398	ND2	ASN	A	322	46.405	−11.483	30.087	1.00	53.78	N
ATOM	1401	C	ASN	A	322	46.639	−9.404	27.111	1.00	55.23	C
ATOM	1402	O	ASN	A	322	46.817	−10.572	26.818	1.00	55.23	O
ATOM	1404	N	LEU	A	323	47.256	−8.396	26.510	1.00	53.84	N
ATOM	1405	CA	LEU	A	323	48.155	−8.559	25.360	1.00	53.07	C
ATOM	1407	CB	LEU	A	323	48.701	−7.196	24.927	1.00	52.47	C
ATOM	1410	CG	LEU	A	323	49.698	−7.102	23.785	1.00	52.78	C
ATOM	1412	CD1	LEU	A	323	49.101	−7.640	22.509	1.00	52.22	C
ATOM	1416	CD2	LEU	A	323	50.106	−5.644	23.610	1.00	53.61	C
ATOM	1420	C	LEU	A	323	49.324	−9.507	25.592	1.00	52.29	C
ATOM	1421	O	LEU	A	323	49.734	−10.125	24.658	1.00	51.98	O
ATOM	1423	N	LEU	A	324	49.858	−9.599	26.811	1.00	52.01	N
ATOM	1424	CA	LEU	A	324	50.987	−10.499	27.096	1.00	52.39	C
ATOM	1426	CB	LEU	A	324	51.576	−10.263	28.491	1.00	51.92	C
ATOM	1429	CG	LEU	A	324	52.753	−11.160	28.912	1.00	51.66	C
ATOM	1431	CD1	LEU	A	324	53.991	−11.039	28.001	1.00	51.19	C
ATOM	1435	CD2	LEU	A	324	53.110	−10.832	30.311	1.00	51.89	C
ATOM	1439	C	LEU	A	324	50.602	−11.988	26.951	1.00	52.94	C
ATOM	1440	O	LEU	A	324	51.338	−12.768	26.336	1.00	52.42	O
ATOM	1442	N	ASP	A	325	49.468	−12.366	27.533	1.00	53.59	N
ATOM	1443	CA	ASP	A	325	48.974	−13.724	27.379	1.00	54.58	C
ATOM	1445	CB	ASP	A	325	47.966	−14.090	28.465	1.00	54.98	C
ATOM	1448	CG	ASP	A	325	48.583	−14.065	29.864	1.00	57.90	C
ATOM	1449	OD1	ASP	A	325	49.792	−14.422	29.992	1.00	61.26	O
ATOM	1450	OD2	ASP	A	325	47.942	−13.695	30.888	1.00	60.00	O
ATOM	1451	C	ASP	A	325	48.400	−13.933	25.998	1.00	54.49	C
ATOM	1452	O	ASP	A	325	48.471	−15.028	25.497	1.00	54.99	O
ATOM	1454	N	TYR	A	326	47.860	−12.890	25.376	1.00	54.48	N
ATOM	1455	CA	TYR	A	326	47.347	−12.987	24.023	1.00	54.35	C
ATOM	1457	CB	TYR	A	326	46.728	−11.666	23.586	1.00	55.11	C
ATOM	1460	CG	TYR	A	326	46.174	−11.719	22.197	1.00	56.05	C
ATOM	1461	CD1	TYR	A	326	44.961	−12.349	21.961	1.00	56.75	C
ATOM	1463	CE1	TYR	A	326	44.428	−12.434	20.686	1.00	56.63	C
ATOM	1465	CZ	TYR	A	326	45.102	−11.867	19.622	1.00	56.70	C
ATOM	1466	OH	TYR	A	326	44.522	−11.992	18.381	1.00	57.16	O
ATOM	1468	CE2	TYR	A	326	46.329	−11.208	19.821	1.00	56.39	C
ATOM	1470	CD2	TYR	A	326	46.868	−11.159	21.108	1.00	56.27	C
ATOM	1472	C	TYR	A	326	48.468	−13.388	23.081	1.00	53.77	C
ATOM	1473	O	TYR	A	326	48.392	−14.424	22.449	1.00	54.36	O
ATOM	1475	N	LEU	A	327	49.514	−12.577	23.041	1.00	53.12	N
ATOM	1476	CA	LEU	A	327	50.718	−12.837	22.250	1.00	52.14	C
ATOM	1478	CB	LEU	A	327	51.782	−11.815	22.588	1.00	51.78	C
ATOM	1481	CG	LEU	A	327	51.578	−10.396	22.107	1.00	52.13	C
ATOM	1483	CD1	LEU	A	327	52.612	−9.475	22.831	1.00	54.47	C
ATOM	1487	CD2	LEU	A	327	51.722	−10.316	20.642	1.00	51.88	C
ATOM	1491	C	LEU	A	327	51.350	−14.192	22.486	1.00	51.44	C
ATOM	1492	O	LEU	A	327	51.778	−14.824	21.537	1.00	51.45	0
ATOM	1494	N	ARG	A	328	51.456	−14.596	23.747	1.00	50.98	N
ATOM	1495	CA	ARG	A	328	52.064	−15.898	24.100	1.00	51.10	C
ATOM	1497	CB	ARG	A	328	52.209	−16.045	25.617	1.00	50.94	C
ATOM	1500	CG	ARG	A	328	53.410	−15.397	26.249	1.00	50.36	C
ATOM	1503	CD	ARG	A	328	53.289	−15.321	27.771	1.00	51.71	C
ATOM	1506	NE	ARG	A	328	54.501	−14.810	28.380	1.00	53.96	N
ATOM	1508	CZ	ARG	A	328	54.655	−14.481	29.664	1.00	55.35	C
ATOM	1509	NH1	ARG	A	328	53.687	−14.670	30.581	1.00	57.04	N
ATOM	1512	NH2	ARG	A	328	55.839	−13.993	30.042	1.00	54.89	N
ATOM	1515	C	ARG	A	328	51.281	−17.120	23.586	1.00	51.26	C
ATOM	1516	O	ARG	A	328	51.868	−18.100	23.195	1.00	50.00	O
ATOM	1518	N	GLU	A	329	49.954	−17.017	23.635	1.00	52.51	N
ATOM	1519	CA	GLU	A	329	49.023	−18.098	23.387	1.00	53.25	C
ATOM	1521	CB	GLU	A	329	47.780	−17.993	24.310	1.00	53.62	C
ATOM	1524	CG	GLU	A	329	47.975	−18.613	25.700	1.00	57.15	C
ATOM	1527	CD	GLU	A	329	47.579	−17.705	26.888	1.00	63.27	C
ATOM	1528	OE1	GLU	A	329	46.461	−17.105	26.890	1.00	66.10	O
ATOM	1529	OE2	GLU	A	329	48.402	−17.583	27.849	1.00	67.56	O
ATOM	1530	C	GLU	A	329	48.602	−18.156	21.936	1.00	53.37	C
ATOM	1531	O	GLU	A	329	48.052	−19.192	21.536	1.00	54.14	O
ATOM	1533	N	CYS	A	330	48.875	−17.116	21.136	1.00	53.25	N
ATOM	1534	CA	CYS	A	330	48.327	−17.031	19.766	1.00	53.54	C
ATOM	1536	CB	CYS	A	330	48.265	−15.601	19.268	1.00	53.40	C
ATOM	1539	SG	CYS	A	330	49.873	−15.008	18.732	1.00	57.08	S
ATOM	1541	C	CYS	A	330	49.058	−17.852	18.698	1.00	53.17	C
ATOM	1542	O	CYS	A	330	50.240	−18.190	18.846	1.00	52.64	O
ATOM	1544	N	ASN	A	331	48.277	−18.169	17.653	1.00	53.38	N
ATOM	1545	CA	ASN	A	331	48.710	−18.569	16.285	1.00	52.93	C
ATOM	1547	CB	ASN	A	331	47.486	−19.166	15.557	1.00	52.32	C
ATOM	1550	CG	ASN	A	331	47.676	−19.381	14.070	1.00	51.85	C
ATOM	1551	OD1	ASN	A	331	48.167	−18.533	13.346	1.00	52.00	O
ATOM	1552	ND2	ASN	A	331	47.187	−20.507	13.594	1.00	52.93	N
ATOM	1555	C	ASN	A	331	49.307	−17.330	15.535	1.00	53.24	C
ATOM	1556	O	ASN	A	331	48.568	−16.404	15.117	1.00	52.88	O
ATOM	1558	N	ARG	A	332	50.626	−17.380	15.301	1.00	53.17	N
ATOM	1559	CA	ARO	A	332	51.414	−16.231	14.795	1.00	52.68	C
ATOM	1561	CB	ARG	A	332	52.895	−16.413	15.158	1.00	52.67	C
ATOM	1564	CG	ARG	A	332	53.163	−16.648	16.633	1.00	51.10	C
ATOM	1567	CD	ARG	A	332	54.590	−16.702	16.951	1.00	49.69	C
ATOM	1570	NE	ARG	A	332	54.852	−16.927	18.369	1.00	48.10	N
ATOM	1572	CZ	ARG	A	332	56.074	−17.005	18.907	1.00	45.55	C
ATOM	1573	NH1	ARG	A	332	57.177	−16.893	18.153	1.00	46.29	N
ATOM	1576	NH2	ARG	A	332	56.197	−17.186	20.208	1.00	42.43	N
ATOM	1579	C	ARG	A	332	51.324	−16.002	13.294	1.00	53.91	C
ATOM	1580	O	ARG	A	332	51.780	−14.968	12.781	1.00	53.57	O
ATOM	1582	N	GLN	A	333	50.769	−16.986	12.590	1.00	55.31	N
ATOM	1583	CA	GLN	A	333	50.434	−16.842	11.166	1.00	56.72	C
ATOM	1585	CB	GLN	A	333	49.995	−18.169	10.503	1.00	57.03	C
ATOM	1588	CG	GLN	A	333	50.601	−19.504	11.021	1.00	59.84	C
ATOM	1591	CD	GLN	A	333	52.087	−19.444	11.422	1.00	63.22	C
ATOM	1592	OE1	GLN	A	333	52.891	−18.682	10.859	1.00	64.83	O
ATOM	1593	NE2	GLN	A	333	52.433	−20.229	12.427	1.00	64.99	N
ATOM	1596	C	GLN	A	333	49.316	−15.784	11.021	1.00	57.10	C
ATOM	1597	O	GLN	A	333	49.374	−14.939	10.124	1.00	57.29	O
ATOM	1599	N	GLU	A	334	48.333	−15.830	11.924	1.00	57.26	N
ATOM	1600	CA	GLU	A	334	47.282	−14.841	11.969	1.00	57.93	C
ATOM	1602	CB	GLU	A	334	46.093	−15.439	12.703	1.00	57.81	C
ATOM	1605	CG	GLU	A	334	44.824	−14.623	12.556	1.00	59.79	C
ATOM	1608	CD	GLU	A	334	43.711	−15.160	13.419	1.00	60.61	C
ATOM	1609	OE1	GLU	A	334	43.301	−16.310	13.150	1.00	65.79	O
ATOM	1610	OE2	GLU	A	334	43.254	−14.444	14.348	1.00	64.99	O
ATOM	1611	C	GLU	A	334	47.765	−13.495	12.616	1.00	57.92	C
ATOM	1612	O	GLU	A	334	47.579	−12.405	12.036	1.00	57.91	O
ATOM	1614	N	VAL	A	335	48.362	−13.597	13.810	1.00	57.54	N
ATOM	1615	CA	VAL	A	335	49.011	−12.481	14.520	1.00	57.11	C
ATOM	1617	CB	VAL	A	335	49.000	−12.731	16.054	1.00	56.99	C
ATOM	1619	CG1	VAL	A	335	49.665	−11.564	16.841	1.00	57.86	C
ATOM	1623	CG2	VAL	A	335	47.582	−12.975	16.563	1.00	56.72	C
ATOM	1627	C	VAL	A	335	50.463	−12.369	13.982	1.00	57.12	C
ATOM	1628	O	VAL	A	335	51.429	−12.835	14.592	1.00	57.16	O
ATOM	1630	N	ASN	A	336	50.598	−11.773	12.807	1.00	56.99	N
ATOM	1631	CA	ASN	A	336	51.851	−11.794	12.029	1.00	56.48	C
ATOM	1633	CB	ASN	A	336	51.544	−12.181	10.561	1.00	56.72	C
ATOM	1636	CG	ASN	A	336	50.867	−11.069	9.769	1.00	57.43	C
ATOM	1637	OD1	ASN	A	336	50.411	−10.071	10.331	1.00	61.57	O
ATOM	1638	ND2	ASN	A	336	50.813	−11.236	8.459	1.00	58.02	N
ATOM	1641	C	ASN	A	336	52.600	−10.467	12.132	1.00	55.12	C
ATOM	1642	O	ASN	A	336	52.102	−9.533	12.736	1.00	54.98	O
ATOM	1644	N	ALA	A	337	53.763	−10.399	11.497	1.00	54.01	N
ATOM	1645	CA	ALA	A	337	54.635	−9.224	11.525	1.00	53.69	C
ATOM	1647	CB	ALA	A	337	55.698	−9.338	10.440	1.00	53.52	C
ATOM	1651	C	ALA	A	337	53.901	−7.876	11.405	1.00	53.41	C
ATOM	1652	O	ALA	A	337	54.078	−6.979	12.231	1.00	52.79	O
ATOM	1654	N	VAL	A	338	53.053	−7.759	10.396	1.00	53.44	N
ATOM	1655	CA	VAL	A	338	52.275	−6.518	10.209	1.00	53.57	C
ATOM	1657	CB	VAL	A	338	51.583	−6.427	8.808	1.00	53.82	C
ATOM	1659	CG1	VAL	A	338	50.550	−7.553	8.573	1.00	53.74	C
ATOM	1663	CG2	VAL	A	338	50.928	−5.010	8.593	1.00	53.91	C
ATOM	1667	C	VAL	A	338	51.254	−6.268	11.341	1.00	52.91	C
ATOM	1668	O	VAL	A	338	51.054	−5.115	11.735	1.00	52.27	O
ATOM	1670	N	VAL	A	339	50.615	−7.329	11.849	1.00	52.29	N
ATOM	1671	CA	VAL	A	339	49.711	−7.161	12.985	1.00	51.79	C
ATOM	1673	CB	VAL	A	339	49.039	−8.465	13.452	1.00	51.84	C
ATOM	1675	CG1	VAL	A	339	48.353	−8.298	14.885	1.00	50.59	C
ATOM	1679	CG2	VAL	A	339	48.033	−8.914	12.421	1.00	50.16	C
ATOM	1683	C	VAL	A	339	50.459	−6.503	14.132	1.00	51.96	C
ATOM	1684	O	VAL	A	339	49.960	−5.499	14.639	1.00	51.30	O
ATOM	1686	N	LEU	A	340	51.660	−7.037	14.468	1.00	51.94	N
ATOM	1687	CA	LEU	A	340	52.527	−6.500	15.555	1.00	51.95	C
ATOM	1689	CB	LEU	A	340	53.866	−7.233	15.651	1.00	51.64	C
ATOM	1692	CG	LEU	A	340	53.886	−8.764	15.795	1.00	53.25	C
ATOM	1694	CD1	LEU	A	340	55.285	−9.281	16.075	1.00	52.63	C
ATOM	1698	CD2	LEU	A	340	52.935	−9.269	16.882	1.00	53.62	C
ATOM	1702	C	LEU	A	340	52.778	−4.996	15.420	1.00	52.11	C
ATOM	1703	O	LEU	A	340	52.789	−4.244	16.408	1.00	53.25	O
ATOM	1705	N	LEU	A	341	52.923	−4.569	14.182	1.00	51.95	N
ATOM	1706	CA	LEU	A	341	53.220	−3.212	13.848	1.00	52.33	C
ATOM	1708	CB	LEU	A	341	53.711	−3.173	12.375	1.00	52.64	C
ATOM	1711	CG	LEU	A	341	54.864	−2.267	11.892	1.00	54.23	C
ATOM	1713	CD1	LEU	A	341	56.093	−2.219	12.805	1.00	53.35	C
ATOM	1717	CD2	LEU	A	341	55.276	−2.663	10.417	1.00	53.46	C
ATOM	1721	C	LEU	A	341	51.986	−2.321	14.144	1.00	52.22	C
ATOM	1722	O	LEU	A	341	52.147	−1.225	14.669	1.00	52.70	O
ATOM	1724	N	TYR	A	342	50.773	−2.827	13.878	1.00	52.15	N
ATOM	1725	CA	TYR	A	342	49.482	−2.135	14.198	1.00	51.96	C
ATOM	1727	CB	TYR	A	342	48.299	−2.945	13.630	1.00	51.65	C
ATOM	1730	CG	TYR	A	342	46.887	−2.336	13.691	1.00	51.98	C
ATOM	1731	CD1	TYR	A	342	46.672	−0.941	13.633	1.00	51.01	C
ATOM	1733	CE1	TYR	A	342	45.374	−0.398	13.688	1.00	50.45	C
ATOM	1735	CZ	TYR	A	342	44.279	−1.244	13.754	1.00	51.02	C
ATOM	1736	OH	TYR	A	342	43.003	−0.685	13.795	1.00	51.89	O
ATOM	1738	CE2	TYR	A	342	44.460	−2.640	13.779	1.00	50.55	C
ATOM	1740	CD2	TYR	A	342	45.748	−3.178	13.743	1.00	49.97	C
ATOM	1742	C	TYR	A	342	49.269	−1.938	15.686	1.00	52.12	C
ATOM	1743	O	TYR	A	342	48.806	−0.891	16.129	1.00	52.02	O
ATOM	1745	N	MET	A	343	49.665	−2.945	16.453	1.00	52.44	N
ATOM	1746	CA	MET	A	343	49.497	−2.944	17.905	1.00	52.85	C
ATOM	1748	CB	MET	A	343	49.816	−4.314	18.488	1.00	52.17	C
ATOM	1751	CG	MET	A	343	48.860	−5.347	17.896	1.00	53.59	C
ATOM	1754	SD	MET	A	343	48.691	−6.887	18.680	1.00	55.71	S
ATOM	1755	CE	MET	A	343	50.344	−7.441	18.756	1.00	55.23	C
ATOM	1759	C	MET	A	343	50.364	−1.885	18.485	1.00	52.32	C
ATOM	1760	O	MET	A	343	49.875	−0.995	19.193	1.00	52.53	O
ATOM	1762	N	ALA	A	344	51.638	−1.933	18.111	1.00	52.07	N
ATOM	1763	CA	ALA	A	344	52.573	−0.868	18.465	1.00	51.62	C
ATOM	1765	CB	ALA	A	344	53.951	−1.153	17.878	1.00	51.90	C
ATOM	1769	C	ALA	A	344	52.081	0.516	18.037	1.00	51.28	C
ATOM	1770	O	ALA	A	344	52.253	1.469	18.782	1.00	51.72	O
ATOM	1772	N	THR	A	345	51.463	0.611	16.855	1.00	50.78	N
ATOM	1773	CA	TER	A	345	50.996	1.897	16.311	1.00	50.28	C
ATOM	1775	CB	THR	A	345	50.568	1.761	14.843	1.00	50.01	C
ATOM	1777	OG1	THR	A	345	51.645	1.230	14.077	1.00	47.39	O
ATOM	1779	CG2	THR	A	345	50.318	3.164	14.233	1.00	49.91	C
ATOM	1783	C	THR	A	345	49.819	2.471	17.078	1.00	49.83	C
ATOM	1784	O	THR	A	345	49.737	3.673	17.279	1.00	48.98	O
ATOM	1786	N	GLN	A	346	48.876	1.589	17.412	1.00	49.88	N
ATOM	1787	CA	GLN	A	346	47.711	1.939	18.243	1.00	49.50	C
ATOM	1789	CB	GLN	A	346	46.809	0.714	18.472	1.00	49.19	C
ATOM	1792	CG	GLN	A	346	46.083	0.234	17.254	1.00	48.02	C
ATOM	1795	CD	GLN	A	346	45.349	−1.060	17.521	1.00	48.89	C
ATOM	1796	OE1	GLN	A	346	44.354	−1.055	18.278	1.00	47.75	O
ATOM	1797	NE2	GLN	A	346	45.822	−2.175	16.926	1.00	44.34	N
ATOM	1800	C	GLN	A	346	48.190	2.473	19.582	1.00	49.15	C
ATOM	1801	O	GLN	A	346	47.789	3.548	20.018	1.00	49.02	O
ATOM	1803	N	ILE	A	347	49.092	1.726	20.197	1.00	48.85	N
ATOM	1804	CA	ILE	A	347	49.515	2.048	21.528	1.00	49.44	C
ATOM	1806	CB	ILE	A	347	50.322	0.900	22.152	1.00	49.65	C
ATOM	1808	CG1	ILE	A	347	49.368	−0.298	22.352	1.00	49.70	C
ATOM	1811	CD1	ILE	A	347	50.031	−1.577	22.599	1.00	50.76	C
ATOM	1815	CG2	ILE	A	347	50.904	1.315	23.523	1.00	49.56	C
ATOM	1819	C	ILE	A	347	50.224	3.382	21.536	1.00	49.59	C
ATOM	1820	O	ILE	A	347	49.936	4.202	22.404	1.00	49.17	O
ATOM	1822	N	SER	A	348	51.078	3.626	20.542	1.00	49.74	N
ATOM	1823	CA	SER	A	348	51.701	4.941	20.389	1.00	50.09	C
ATOM	1825	CB	SER	A	348	52.726	4.954	19.243	1.00	49.95	C
ATOM	1828	OG	SER	A	348	52.279	4.291	18.081	1.00	49.56	O
ATOM	1830	C	SER	A	348	50.652	6.065	20.247	1.00	50.75	C
ATOM	1831	O	SER	A	348	50.768	7.117	20.881	1.00	51.02	O
ATOM	1833	N	SER	A	349	49.595	5.816	19.485	1.00	51.78	N
ATOM	1834	CA	SER	A	349	48.547	6.817	19.294	1.00	52.48	C
ATOM	1836	CB	SER	A	349	47.418	6.287	18.444	1.00	52.11	C
ATOM	1839	OG	SER	A	349	46.588	7.370	18.164	1.00	54.26	O
ATOM	1841	C	SER	A	349	47.977	7.313	20.620	1.00	52.81	C
ATOM	1842	O	SER	A	349	47.901	8.524	20.859	1.00	52.83	O
ATOM	1844	N	ALA	A	350	47.619	6.359	21.476	1.00	53.39	N
ATOM	1845	CA	ALA	A	350	47.093	6.663	22.822	1.00	53.78	C
ATOM	1847	CB	ALA	A	350	46.609	5.393	23.480	1.00	53.95	C
ATOM	1851	C	ALA	A	350	48.063	7.372	23.779	1.00	53.96	C
ATOM	1852	O	ALA	A	350	47.615	8.035	24.722	1.00	54.73	O
ATOM	1854	N	MET	A	351	49.366	7.180	23.565	1.00	53.72	N
ATOM	1855	CA	MET	A	351	50.408	7.732	24.413	1.00	53.43	C
ATOM	1857	CB	MET	A	351	51.612	6.827	24.385	1.00	53.33	C
ATOM	1860	CG	MET	A	351	51.393	5.506	25.060	1.00	53.80	C
ATOM	1863	SD	MET	A	351	50.982	5.577	26.819	1.00	55.30	S
ATOM	1864	CE	MET	A	351	52.240	6.513	27.585	1.00	57.96	C
ATOM	1868	C	MET	A	351	50.811	9.131	23.992	1.00	53.93	C
ATOM	1869	O	MET	A	351	51.166	9.960	24.831	1.00	52.90	O
ATOM	1871	N	GLU	A	352	50.778	9.390	22.694	1.00	54.74	N
ATOM	1872	CA	GLU	A	352	50.848	10.756	22.200	1.00	56.24	C
ATOM	1874	CB	GLU	A	352	50.792	10.751	20.687	1.00	56.27	C
ATOM	1877	CG	GLU	A	352	50.817	12.126	20.017	1.00	57.41	C
ATOM	1880	CD	GLU	A	352	50.642	12.033	18.512	1.00	58.76	C
ATOM	1881	OE1	GLU	A	352	50.134	10.976	18.034	1.00	64.72	O
ATOM	1882	OE2	GLU	A	352	51.018	13.003	17.801	1.00	60.35	O
ATOM	1883	C	GLU	A	352	49.689	11.606	22.745	1.00	56.18	C
ATOM	1884	O	GLU	A	352	49.882	12.808	23.011	1.00	56.18	O
ATOM	1886	N	TYR	A	353	48.502	10.990	22.858	1.00	56.38	N
ATOM	1887	CA	TYR	A	353	47.310	11.639	23.426	1.00	56.45	C
ATOM	1889	CB	TYR	A	353	46.060	10.745	23.266	1.00	56.57	C
ATOM	1892	CG	TYR	A	353	44.797	11.231	23.969	1.00	56.99	C
ATOM	1893	CD1	TYR	A	353	44.023	12.288	23.447	1.00	57.49	C
ATOM	1895	CE1	TYR	A	353	42.856	12.744	24.111	1.00	56.27	C
ATOM	1897	CZ	TYR	A	353	42.457	12.124	25.289	1.00	56.81	C
ATOM	1898	OH	TYR	A	353	41.318	12.536	25.955	1.00	57.14	O
ATOM	1900	CE2	TYR	A	353	43.201	11.067	25.813	1.00	56.88	C
ATOM	1902	CD2	TYR	A	353	44.357	10.625	25.157	1.00	57.07	C
ATOM	1904	C	TYR	A	353	47.599	11.986	24.880	1.00	56.93	C
ATOM	1905	O	TYR	A	353	47.515	13.148	25.269	1.00	56.46	O
ATOM	1907	N	LEU	A	354	48.007	10.984	25.659	1.00	57.62	N
ATOM	1908	CA	LEU	A	354	48.389	11.199	27.063	1.00	58.03	C
ATOM	1910	CB	LEU	A	354	48.769	9.875	27.720	1.00	57.98	C
ATOM	1913	CG	LEU	A	354	47.692	9.076	28.468	1.00	59.37	C
ATOM	1915	CD1	LEU	A	354	46.305	9.179	27.855	1.00	61.13	C
ATOM	1919	CD2	LEU	A	354	48.087	7.600	28.598	1.00	58.39	C
ATOM	1923	C	LEU	A	354	49.507	12.224	27.222	1.00	58.26	C
ATOM	1924	O	LEU	A	354	49.441	13.050	28.112	1.00	58.67	O
ATOM	1926	N	GLU	A	355	50.510	12.164	26.347	1.00	58.64	N
ATOM	1927	CA	GLU	A	355	51.601	13.154	26.278	1.00	58.85	C
ATOM	1929	CB	GLU	A	355	52.604	12.715	25.190	1.00	58.98	C
ATOM	1932	CG	GLU	A	355	53.784	13.631	24.847	1.00	59.78	C
ATOM	1935	CD	GLU	A	355	54.477	13.209	23.549	1.00	61.24	C
ATOM	1936	OE1	GLU	A	355	53.920	13.513	22.451	1.00	63.60	O
ATOM	1937	OE2	GLU	A	355	55.555	12.548	23.629	1.00	63.93	O
ATOM	1938	C	GLU	A	355	51.112	14.601	26.027	1.00	58.65	C
ATOM	1939	O	GLU	A	355	51.752	15.556	26.497	1.00	57.91	O
ATOM	1941	N	LYS	A	356	50.008	14.747	25.283	1.00	58.75	N
ATOM	1942	CA	LYS	A	356	49.436	16.075	24.938	1.00	59.18	C
ATOM	1944	CB	LYS	A	356	48.437	16.005	23.758	1.00	58.87	C
ATOM	1947	CG	LYS	A	356	48.797	16.898	22.576	1.00	61.02	C
ATOM	1950	CD	LYS	A	356	47.563	17.543	21.890	1.00	62.28	C
ATOM	1953	CE	LYS	A	356	46.584	16.535	21.232	1.00	65.16	C
ATOM	1956	NZ	LYS	A	356	45.452	17.270	20.510	1.00	64.83	N
ATOM	1960	C	LYS	A	356	48.750	16.656	26.165	1.00	58.24	C
ATOM	1961	O	LYS	A	356	48.938	17.826	26.495	1.00	57.93	O
ATOM	1963	N	LYS	A	357	47.981	15.808	26.842	1.00	57.84	N
ATOM	1964	CA	LYS	A	357	47.324	16.152	28.109	1.00	57.62	C
ATOM	1966	CB	LYS	A	357	46.173	15.155	28.426	1.00	57.35	C
ATOM	1969	CG	LYS	A	357	45.115	14.990	27.333	1.00	58.70	C
ATOM	1972	CD	LYS	A	357	43.715	14.649	27.915	1.00	59.47	C
ATOM	1975	CE	LYS	A	357	42.817	15.920	28.167	1.00	61.35	C
ATOM	1978	NZ	LYS	A	357	41.740	15.731	29.238	1.00	61.43	N
ATOM	1982	C	LYS	A	357	48.279	16.235	29.323	1.00	56.77	C
ATOM	1983	O	LYS	A	357	47.819	16.557	30.398	1.00	56.59	O
ATOM	1985	N	ASN	A	358	49.570	15.936	29.164	1.00	56.33	N
ATOM	1986	CA	ASN	A	358	50.543	15.848	30.274	1.00	56.66	C
ATOM	1988	CB	ASN	A	358	50.749	17.231	30.912	1.00	56.15	C
ATOM	1991	CG	ASN	A	358	52.137	17.392	31.539	1.00	56.69	C
ATOM	1992	OD1	ASN	A	358	53.178	17.171	30.886	1.00	58.14	O
ATOM	1993	ND2	ASN	A	358	52.159	17.745	32.816	1.00	54.39	N
ATOM	1996	C	ASN	A	358	50.313	14.731	31.354	1.00	56.66	C
ATOM	1997	O	ASN	A	358	50.644	14.895	32.555	1.00	55.97	O
ATOM	1999	N	PHE	A	359	49.802	13.585	30.897	1.00	56.72	N
ATOM	2000	CA	PHE	A	359	49.605	12.415	31.746	1.00	57.52	C
ATOM	2002	CB	PHE	A	359	48.360	11.629	31.299	1.00	58.78	C
ATOM	2005	CG	PHE	A	359	47.094	12.192	31.820	1.00	59.04	C
ATOM	2006	CD1	PHE	A	359	46.622	13.418	31.332	1.00	62.61	C
ATOM	2008	CE1	PHE	A	359	45.400	14.032	31.831	1.00	61.37	C
ATOM	2010	CZ	PHE	A	359	44.687	13.399	32.845	1.00	61.22	C
ATOM	2012	CE2	PHE	A	359	45.174	12.135	33.347	1.00	62.29	C
ATOM	2014	CD2	PHE	A	359	46.371	11.545	32.818	1.00	60.64	C
ATOM	2016	C	PHE	A	359	50.845	11.515	31.702	1.00	57.59	C
ATOM	2017	O	PHE	A	359	51.493	11.460	30.685	1.00	58.75	O
ATOM	2019	N	ILE	A	360	51.192	10.839	32.787	1.00	56.99	N
ATOM	2020	CA	ILE	A	360	52.056	9.657	32.690	1.00	57.39	C
ATOM	2022	CB	ILE	A	360	53.287	9.660	33.655	1.00	57.76	C
ATOM	2024	CG1	ILE	A	360	52.897	9.824	35.137	1.00	58.11	C
ATOM	2027	CD1	ILE	A	360	54.060	9.883	36.079	1.00	58.13	C
ATOM	2031	CG2	ILE	A	360	54.282	10.703	33.229		1.00	57.51	C
ATOM	2035	C	ILE	A	360	51.153	8.527	33.012	1.00	56.96	C
ATOM	2036	O	ILE	A	360	50.271	8.718	33.828	1.00	57.32	O
ATOM	2038	N	HIS	A	361	51.325	7.394	32.335	1.00	56.59	N
ATOM	2039	CA	HIS	A	361	50.718	6.107	32.727	1.00	56.34	C
ATOM	2041	CB	HIS	A	361	50.863	5.060	31.608	1.00	56.14	C
ATOM	2044	CG	HIS	A	361	49.999	3.859	31.797	1.00	54.84	C
ATOM	2045	ND1	HIS	A	361	50.466	2.674	32.310	1.00	54.23	N
ATOM	2047	CE1	HIS	A	361	49.473	1.810	32.405	1.00	53.40	C
ATOM	2049	NE2	HIS	A	361	48.380	2.393	31.972	1.00	54.30	N
ATOM	2051	CD2	HIS	A	361	48.675	3.683	31.606	1.00	54.59	C
ATOM	2053	C	HIS	A	361	51.431	5.555	33.938	1.00	57.04	C
ATOM	2054	O	HIS	A	361	50.811	5.006	34.868	1.00	56.47	O
ATOM	2056	N	ARG	A	362	52.764	5.630	33.873	1.00	58.13	N
ATOM	2057	CA	ARG	A	362	53.670	5.149	34.936	1.00	59.12	C
ATOM	2059	CB	ARG	A	362	53.408	5.910	36.262	1.00	59.96	C
ATOM	2062	CG	ARG	A	362	54.630	6.418	37.014	1.00	61.64	C
ATOM	2065	CD	ARG	A	362	54.472	6.384	38.571	1.00	62.77	C
ATOM	2068	NE	ARG	A	362	53.174	6.872	39.071	1.00	63.86	N
ATOM	2070	CZ	ARG	A	362	52.809	6.857	40.363	1.00	64.88	C
ATOM	2071	NH1	ARG	A	362	53.623	6.402	41.314	1.00	66.44	N
ATOM	2074	NH2	ARG	A	362	51.624	7.340	40.729	1.00	65.03	N
ATOM	2077	C	ARG	A	362	53.670	3.619	35.170	1.00	57.97	C
ATOM	2078	O	ARG	A	362	54.380	3.199	36.039	1.00	58.27	O
ATOM	2080	N	ASP	A	363	52.922	2.812	34.401	1.00	57.45	N
ATOM	2081	CA	ASP	A	363	52.996	1.315	34.429	1.00	57.10	C
ATOM	2083	CB	ASP	A	363	52.150	0.679	35.577	1.00	56.55	C
ATOM	2086	CG	ASP	A	363	52.383	−0.845	35.721	1.00	58.60	C
ATOM	2087	OD1	ASP	A	363	53.440	−1.365	35.254	1.00	62.48	O
ATOM	2088	OD2	ASP	A	363	51.548	−1.632	36.226	1.00	60.76	O
ATOM	2089	C	ASP	A	363	52.651	0.684	33.036	1.00	55.60	C
ATOM	2090	O	ASP	A	363	51.767	−0.155	32.896	1.00	56.32	O
ATOM	2092	N	LEU	A	364	53.387	1.082	32.019	1.00	53.90	N
ATOM	2093	CA	LEU	A	364	53.119	0.660	30.656	1.00	53.22	C
ATOM	2095	CB	LEU	A	364	53.691	1.697	29.732	1.00	52.89	C
ATOM	2098	CG	LEU	A	364	53.155	1.663	28.334	1.00	54.86	C
ATOM	2100	CD1	LEU	A	364	51.636	1.946	28.288	1.00	55.65	C
ATOM	2104	CD2	LEU	A	364	53.947	2.720	27.538	1.00	57.12	C
ATOM	2108	C	LEU	A	364	53.776	−0.687	30.355	1.00	52.95	C
ATOM	2109	O	LEU	A	364	54.998	−0.830	30.537	1.00	54.77	O
ATOM	2111	N	ALA	A	365	53.001	−1.662	29.899	1.00	50.88	N
ATOM	2112	CA	ALA	A	365	53.495	−3.011	29.711	1.00	49.55	C
ATOM	2114	CB	ALA	A	365	53.922	−3.589	31.036	1.00	49.24	C
ATOM	2118	C	ALA	A	365	52.452	−3.937	29.063	1.00	49.17	C
ATOM	2119	O	ALA	A	365	51.256	−3.741	29.207	1.00	47.53	O
ATOM	2121	N	ALA	A	366	52.940	−4.996	28.425	1.00	49.72	N
ATOM	2122	CA	ALA	A	366	52.118	−5.946	27.658	1.00	50.24	C
ATOM	2124	CB	ALA	A	366	52.953	−7.095	27.202	1.00	49.81	C
ATOM	2128	C	ALA	A	366	50.929	−6.452	28.453	1.00	50.59	C
ATOM	2129	O	ALA	A	366	49.812	−6.330	27.982	1.00	50.28	O
ATOM	2131	N	ARG	A	367	51.185	−6.935	29.680	1.00	51.46	N
ATOM	2132	CA	ARG	A	367	50.136	−7.314	30.660	1.00	52.33	C
ATOM	2134	CB	ARG	A	367	50.773	−7.718	31.988	1.00	52.44	C
ATOM	2137	CG	ARG	A	367	51.368	−6.589	32.796	1.00	53.50	C
ATOM	2140	CD	ARG	A	367	52.072	−6.977	34.119	1.00	55.16	C
ATOM	2143	NE	ARG	A	367	52.654	−5.752	34.715	1.00	57.55	N
ATOM	2145	CZ	ARG	A	367	53.898	−5.232	34.490	1.00	59.68	C
ATOM	2146	NH1	ARG	A	367	54.814	−5.846	33.717	1.00	59.88	N
ATOM	2149	NH2	ARG	A	367	54.238	−4.072	35.086	1.00	59.93	N
ATOM	2152	C	ARG	A	367	49.023	−6.295	30.982	1.00	52.96	C
ATOM	2153	O	ARG	A	367	47.953	−6.699	31.403	1.00	53.67	O
ATOM	2155	N	ASN	A	368	49.318	−4.995	30.866	1.00	53.77	N
ATOM	2156	CA	ASN	A	368	48.353	−3.882	31.064	1.00	54.07	C
ATOM	2158	CB	ASN	A	368	49.056	−2.722	31.804	1.00	54.24	C
ATOM	2161	CG	ASN	A	368	49.390	−3.086	33.234	1.00	56.11	C
ATOM	2162	OD1	ASN	A	368 48.635	−3.843	33.883	1.00	58.47	O
ATOM	2163	ND2	ASN	A	368 50.520	−2.576	33.744	1.00	56.09	N
ATOM	2166	C	ASN	A	368	47.665	−3.363	29.782	1.00	54.37	C
ATOM	2167	O	ASN	A	368	46.982	−2.329	29.810	1.00	53.43	O
ATOM	2169	N	CYS	A	369	47.852	−4.087	28.671	1.00	54.80	N
ATOM	2170	CA	CYS	A	369	47.190	−3.807	27.400	1.00	55.20	C
ATOM	2172	CB	CYS	A	369	48.172	−3.844	26.232	1.00	55.73	C
ATOM	2175	SG	CYS	A	369	49.292	−2.416	26.161	1.00	58.82	S
ATOM	2177	C	CYS	A	369	46.173	−4.873	27.201	1.00	54.94	C
ATOM	2178	O	CYS	A	369	46.459	−6.017	27.462	1.00	54.51	O
ATOM	2180	N	LEU	A	370	45.009	−4.479	26.711	1.00	55.57	N
ATOM	2181	CA	LEU	A	370	43.898	−5.367	26.482	1.00	56.67	C
ATOM	2183	CB	LEU	A	370	42.702	−4.891	27.287	1.00	56.78	C
ATOM	2186	CC	LEU	A	370	42.893	−5.112	28.791	1.00	55.78	C
ATOM	2188	CD1	LEU	A	370	41.825	−4.348	29.533	1.00	55.28	C
ATOM	2192	CD2	LEU	A	370	42.874	−6.579	29.176	1.00	54.67	C
ATOM	2196	C	LEU	A	370	43.563	−5.419	24.998	1.00	57.88	C
ATOM	2197	O	LEU	A	370	43.827	−4.454	24.282	1.00	57.65	O
ATOM	2199	N	VAL	A	371	42.978	−6.545	24.568	1.00	59.20	N
ATOM	2200	CA	VAL	A	371	42.690	−6.836	23.152	1.00	60.77	C
ATOM	2202	CB	VAL	A	371	43.548	−8.034	22.693	1.00	61.16	C
ATOM	2204	CC1	VAL	A	371 43.586	−8.163	21.135	1.00	60.80	C
ATOM	2208	CG2	VAL	A	371 44.995	−7.922	23.261	1.00	61.81	C
ATOM	2212	C	VAL	A	371	41.186	−7.127	22.837	1.00	61.14	C
ATOM	2213	O	VAL	A	371	40.486	−7.813	23.604	1.00	61.52	O
ATOM	2215	N	GLY	A	372	40.717	−6.602	21.708	1.00	61.60	N
ATOM	2216	CA	GLY	A	372	39.396	−6.941	21.145	1.00	62.33	C
ATOM	2219	C	GLY	A	372	39.422	−7.654	19.791	1.00	63.36	C
ATOM	2220	O	GLY	A	372	40.482	−8.079	19.287	1.00	63.33	O
ATOM	2222	N	GLU	A	373	38.234	−7.769	19.192	1.00	64.32	N
ATOM	2223	CA	GLU	A	373	38.082	−8.362	17.854	1.00	64.77	C
ATOM	2225	CB	GLU	A	373	36.594	−8.462	17.420	1.00	65.14	C
ATOM	2228	CC	GLU	A	373	35.716	−9.433	18.219	1.00	66.24	C
ATOM	2231	CD	GLU	A	373	36.078	−10.916	18.038	1.00	69.46	C
ATOM	2232	OE1	GLU	A	373	36.931	−11.296	17.183	1.00	70.44	O
ATOM	2233	OE2	GLU	A	373	35.514	−11.739	18.788	1.00	72.43	O
ATOM	2234	C	GLU	A	373	38.852	−7.519	16.834	1.00	64.57	C
ATOM	2235	O	GLU	A	373	38.887	−6.269	16.931	1.00	64.10	O
ATOM	2237	N	ASN	A	374	39.455	−8.227	15.870	1.00	64.46	N
ATOM	2238	CA	ASN	A	374	40.229	−7.625	14.774	1.00	64.03	C
ATOM	2240	CB	ASN	A	374	39.313	−6.746	13.884	1.00	64.03	C
ATOM	2243	CG	ASN	A	374	37.933	−7.378	13.631	1.00	62.67	C
ATOM	2244	OD1	ASN	A	374	37.767	−8.216	12.750	1.OQ	60.24	O
ATOM	2245	ND2	ASN	A	374	36.951	−6.968	14.420	1.00	60.66	N
ATOM	2248	C	ASN	A	374	41.474	−6.853	15.286	1.00	64.05	C
ATOM	2249	O	ASN	A	374	41.811	−5.759	14.794	1.00	63.76	O
ATOM	2251	N	HIS	A	375	42.124	−7.421	16.312	1.00	63.89	N
ATOM	2252	CA	HIS	A	375	43.398	−6.909	16.852	1.00	63.66	C
ATOM	2254	CB	HIS	A	375	44.510	−7.274	15.887	1.00	63.72	C
ATOM	2257	CG	HIS	A	375	44.505	−8.729	15.567	1.00	64.44	C
ATOM	2258	ND1	HIS	A	375	44.529	−9.229	14.282	1.00	64.59	N
ATOM	2260	CE1	HIS	A	375	44.448	−10.549	14.334	1.00	66.15	C
ATOM	2262	NE2	HIS	A	375	44.334	−10.915	15.600	1.00	65.60	N
ATOM	2264	CD2	HIS	A	375	44.343	−9.791	16.386	1.00	64.61	C
ATOM	2266	C	HIS	A	375	43.379	−5.439	17.225	1.006	3.18	C
ATOM	2267	O	HIS	A	375	44.354	−4.693	17.059	1.00	62.77	O
ATOM	2269	N	LEU	A	376	42.223	−5.055	17.763	1.00	62.88	N
ATOM	2270	CA	LEU	A	376	42.065	−3.800	18.464	1.00	62.41	C
ATOM	2272	CB	LEU	A	376	40.586	−3.527	18.815	1.00	62.22	C
ATOM	2275	CG	LED	A	376	40.053	−2.113	18.583	1.00	62.21	C
ATOM	2277	CD1	LED	A	376	38.750	−1.959	19.332	1.00	62.60	C
ATOM	2281	CD2	LED	A	376	41.016	−1.004	18.977	1.00	62.02	C
ATOM	2285	C	LEU	A	376	42.903	−3.998	19.733	1.00	61.90	C
ATOM	2286	O	LEU	A	376	42.921	−5.099	20.310	1.00	61.49	O
ATOM	2288	N	VAL	A	377	43.652	−2.966	20.109	1.00	61.32	N
ATOM	2289	CA	VAL	A	377	44.405	−2.953	21.367	1.00	60.57	C
ATOM	2291	CB	VAL	A	377	45.921	−3.264	21.182	1.00	60.17	C
ATOM	2293	CG1	VAL	A	377	46.658	−3.204	22.514	1.00	60.72	C
ATOM	2297	CG2	VAL	A	377	46.122	−4.628	20.584	1.00	59.80	C
ATOM	2301	C	VAL	A	377	44.176	−1.593	22.021	1.00	60.34	C
ATOM	2302	O	VAL	A	377	44.138	−0.546	21.334	1.00	59.94	O
ATOM	2304	N	LYS	A	378	44.006	−1.632	23.343	1.00	60.16	N
ATOM	2305	CA	LYS	A	378	43.843	−0.437	24.152	1.00	60.17	C
ATOM	2307	CB	LYS	A	378	42.370	−0.222	24.518	1.00	60.54	C
ATOM	2310	CG	LYS	A	378	41.395	−0.222	23.357	1.00	60.58	C
ATOM	2313	CD	LYS	A	378	39.985	0.022	23.822	1.00	61.22	C
ATOM	2316	CE	LYS	A	378	38.995	−0.089	22.654	1.00	62.94	C
ATOM	2319	NZ	LYS	A	378	37.887	0.911	22.722	1.00	63.18	N
ATOM	2323	C	LYS	A	378	44.672	−0.516	25.424	1.00	59.64	C
ATOM	2324	O	LYS	A	378	44.861	−1.575	26.006	1.00	58.88	O
ATOM	2326	N	VAL	A	379	45.112	0.650	25.865	1.00	60.09	N
ATOM	2327	CA	VAL	A	379	45.884	0.794	27.076	1.00	60.50	C
ATOM	2329	CB	VAL	A	379	46.772	2.065	27.070	1.00	60.61	C
ATOM	2331	CG1	VAL	A	379	47.792	1.991	28.187	1.00	61.44	C
ATOM	2335	CG2	VAL	A	379	47.499	2.262	25.734	1.00	60.54	C
ATOM	2339	C	VAL	A	379	44.854	0.863	28.227	1.00	60.94	C
ATOM	2340	O	VAL	A	379	43.787	1.477	28.091	1.00	60.32	O
ATOM	2342	N	ALA	A	380	45.213	0.226	29.346	1.00	61.40	N
ATOM	2343	CA	ALA	A	380	44.341	−0.021	30.495	1.00	61.23	C
ATOM	2345	CB	ALA	A	380	43.790	−1.413	30.392	1.00	60.79	C
ATOM	2349	C	ALA	A	380	45.121	0.155	31.813	1.00	61.71	C
ATOM	2350	O	ALA	A	380	46.338	0.471	31.800	1.00	62.08	O
ATOM	2352	N	ASP	A	381	44.420	−0.068	32.930	1.00	61.96	N
ATOM	2353	CA	ASP	A	381	44.981	−0.051	34.294	1.00	61.39	C
ATOM	2355	CB	ASP	A	381	45.960	−1.225	34.529	1.00	61.73	C
ATOM	2358	CG	ASP	A	381	46.388	−1.377	36.031	1.00	64.32	C
ATOM	2359	OD1	ASP	A	381	45.914	−0.607	36.914	1.00	69.30	O
ATOM	2360	OD2	ASP	A	381	47.223	−2.231	36.435	1.00	70.09	O
ATOM	2361	C	ASP	A	381	45.566	1.312	34.669	1.00	60.20	C
ATOM	2362	O	ASP	A	381	46.757	1.485	34.749	1.00	60.44	O
ATOM	2364	N	PHE	A	382	44.695	2.265	34.944	1.00	59.40	N
ATOM	2365	CA	PHE	A	382	45.109	3.669	35.118	1.00	59.19	C
ATOM	2367	CB	PHE	A	382	44.075	4.579	34.440	1.00	59.11	C
ATOM	2370	CG	PHE	A	382	43.970	4.330	32.955	1.00	59.61	C
ATOM	2371	CD1	PHE	A	382	44.955	4.831	32.093	1.00	58.60	C
ATOM	2373	CE1	PEE	A	382	44.894	4.573	30.745	1.00	59.35	C
ATOM	2375	CZ	PHE	A	382	43.826	3.785	30.219	1.00	59.59	C
ATOM	2377	CE2	PHE	A	382	42.843	3.269	31.071	1.00	57.52	C
ATOM	2379	CD2	PHE	A	382	42.928	3.530	32.426	1.00	58.91	C
ATOM	2381	C	PHE	A	382	45.409	4.108	36.571	1.00	59.00	C
ATOM	2382	O	PHE	A	382	45.592	5.307	36.827	1.00	57.78	O
ATOM	2384	N	GLY	A	383	45.488	3.124	37.489	1.00	58.98	N
ATOM	2385	CA	GLY	A	383	45.755	3.333	38.920	1.00	58.78	C
ATOM	2388	C	GLY	A	383	46.906	4.253	39.279	1.00	58.72	C
ATOM	2389	O	GLY	A	383	46.735	5.106	40.129	1.00	58.62	O
ATOM	2391	N	LEU	A	384	48.054	4.086	38.613	1.00	58.79	N
ATOM	2392	CA	LEU	A	384	49.228	4.901	38.843	1.00	59.18	C
ATOM	2394	CB	LEU	A	384	50.506	4.080	38.670	1.00	59.34	C
ATOM	2397	CG	LEU	A	384	50.791	2.720	39.306	1.00	59.79	C
ATOM	2399	CD1	LEU	A	384	52.253	2.387	39.059	1.00	59.46	C
ATOM	2403	CD2	LEU	A	384	50.500	2.670	40.780	1.00	61.54	C
ATOM	2407	C	LEU	A	384	49.325	6.100	37.892	1.00	60.19	C
ATOM	2408	O	LEU	A	384	50.370	6.775	37.852	1.00	60.78	O
ATOM	2410	N	SER	A	385	48.297	6.358	37.087	1.00	60.74	N
ATOM	2411	CA	SER	A	385	48.351	7.453	36.128	1.00	60.72	C
ATOM	2413	CB	SER	A	385	47.319	7.294	35.052	1.00	60.64	C
ATOM	2416	OG	SER	A	385	47.427	5.988	34.565	1.00	64.31	O
ATOM	2418	C	SER	A	385	48.058	8.707	36.861	1.00	60.72	C
ATOM	2419	O	SER	A	385	47.093	8.744	37.622	1.00	61.12	O
ATOM	2421	N	ARG	A	386	48.882	9.722	36.613	1.00	60.79	N
ATOM	2422	CA	ARG	A	386	48.759	11.049	37.197	1.00	60.48	C
ATOM	2424	CB	ARG	A	386	49.986	11.336	38.053	1.00	60.63	C
ATOM	2427	CG	ARG	A	386	50.223	10.342	39.194	1.00	61.37	C
ATOM	2430	CD	ARG	A	386	49.496	10.639	40.518	1.00	62.33	C
ATOM	2433	NE	ARG	A	386	49.484	9.438	41.368	1.00	63.78	N
ATOM	2435	CZ	ARG	A	386	48.658	8.373	41.237	1.00	63.16	C
ATOM	2436	NH1	ARG	A	386	47.751	8.309	40.269	1.00	63.46	N
ATOM	2439	NH2	ARG	A	386	48.767	7.351	42.078	1.00	62.04	N
ATOM	2442	C	ARG	A	386	48.683	12.052	36.067	1.00	60.06	C
ATOM	2443	O	ARG	A	386	49.185	11.777	35.006	1.00	59.42	O
ATOM	2445	N	LEU	A	387	47.998	13.173	36.277	1.00	60.69	N
ATOM	2446	CA	LEU	A	387	48.208	14.364	35.458	1.00	61.26	C
ATOM	2448	CB	LEU	A	387	46.953	15.219	35.264	1.00	61.15	C
ATOM	2451	CG	LEU	A	387	47.238	16.599	34.593	1.00	61.19	C
ATOM	2453	CD1	LEU	A	387 46.324	16.852	33.421	1.00	62.20	C
ATOM	2457	CD2	LEU	A	387 47.169	17.767	35.585	1.00	61.56	C
ATOM	2461	C	LEU	A	387	49.236	15.160	36.213	1.00	61.64	C
ATOM	2462	O	LEU	A	387	48.963	15.583	37.322	1.00	62.25	O
ATOM	2464	N	MET	A	388	50.392	15.384	35.609	1.00	62.04	N
ATOM	2465	CA	MET	A	388	51.443	16.138	36.268	1.00	62.74	C
ATOM	2467	CB	MET	A	388	52.799	15.786	35.713	1.00	62.94	C
ATOM	2470	CG	MET	A	388	53.157	14.351	35.830	1.00	63.04	C
ATOM	2473	SD	MET	A	388	54.862	14.300	35.451	1.00	64.63	S
ATOM	2474	CE	MET	A	388	54.904	14.808	33.677	1.00	64.63	C
ATOM	2478	C	MET	A	388	51.260	17.634	36.084	1.00	62.32	C
ATOM	2479	O	MET	A	388	50.929	18.093	35.003	1.00	61.54	O
ATOM	2481	N	THR	A	389	51.460	18.362	37.171	1.00	62.55	N
ATOM	2482	CA	THR	A	389	51.901	19.742	37.116	1.00	63.55	C
ATOM	2484	CB	THR	A	389	51.387	20.489	38.326	1.00	64.05	C
ATOM	2486	OG1	THR	A	389	49.969	20.259	38.454	1.00	66.31	O
ATOM	2488	CG2	THR	A	389	51.533	21.992	38.128	1.00	64.34	C
ATOM	2492	C	THR	A	389	53.428	19.676	37.125	1.00	63.41	C
ATOM	2493	O	THR	A	389	54.011	18.898	37.927	1.00	64.15	O
ATOM	2495	N	GLY	A	390	54.067	20.434	36.224	1.00	62.43	N
ATOM	2496	CA	GLY	A	390	55.496	20.236	35.906	1.00	62.03	C
ATOM	2499	C	GLY	A	390	55.840	18.940	35.165	1.00	61.54	C
ATOM	2500	O	GLY	A	390	54.976	18.119	34.922	1.00	61.59	O
ATOM	2502	N	ASP	A	391	57.123	18.731	34.864	1.00	61.75	N
ATOM	2503	CA	ASP	A	391	57.595	17.617	33.992	1.00	61.90	C
ATOM	2505	CB	ASP	A	391	58.784	18.103	33.142	1.00	62.78	C
ATOM	2508	CG	ASP	A	391	58.349	18.819	31.894	1.00	64.21	C
ATOM	2509	OD1	ASP	A	391	57.596	18.206	31.094	1.00	65.43	O
ATOM	2510	OD2	ASP	A	391	58.732	19.982	31.631	1.00	68.16	O
ATOM	2511	C	ASP	A	391	58.000	16.325	34.677	1.00	61.28	C
ATOM	2512	O	ASP	A	391	58.539	15.424	34.015	1.00	60.82	O
ATOM	2514	N	THR	A	392	57.665	16.200	35.964	1.00	60.74	N
ATOM	2515	CA	THR	A	392	58.343	15.292	36.890	1.00	60.12	C
ATOM	2517	CB	THR	A	392	59.593	16.038	37.477	1.00	60.00	C
ATOM	2519	OG1	THR	A	392	60.513	16.348	36.429	1.00	61.67	O
ATOM	2521	CG2	THR	A	392	60.402	15.174	38.416	1.00	59.60	C
ATOM	2525	C	THR	A	392	57.429	14.914	38.047	1.00	59.38	C
ATOM	2526	O	THR	A	392	57.183	15.755	38.933	1.00	60.19	O
ATOM	2528	N	TYR	A	393	56.942	13.679	38.053	1.00	58.12	N
ATOM	2529	CA	TYR	A	393	56.362	13.070	39.252	1.00	57.57	C
ATOM	2531	CB	TYR	A	393	55.152	12.158	38.897	1.00	58.36	C
ATOM	2534	CG	TYR	A	393	54.597	11.353	40.060	1.00	58.49	C
ATOM	2535	CD1	TYR	A	393	55.248	10.199	40.485	1.00	59.65	C
ATOM	2537	CE1	TYR	A	393	54.801	9.438	41.560	1.00	60.00	C
ATOM	2539	CZ	TYR	A	393	53.671	9.805	42.255	1.00	59.96	C
ATOM	2540	OH	TYR	A	393	53.353	8.931	43.277	1.00	61.50	O
ATOM	2542	CE2	TYR	A	393	52.936	10.952	41.864	1.00	58.92	C
ATOM	2544	CD2	TYR	A	393	53.427	11.737	40.742	1.00	60.07	C
ATOM	2546	C	TYR	A	393	57.491	12.290	39.938	1.00	56.90	C
ATOM	2547	O	TYR	A	393	58.133	11.490	39.295	1.00	56.34	O
ATOM	2549	N	THR	A	394	57.674	12.502	41.244	1.00	56.49	N
ATOM	2550	CA	THR	A	394	58.640	11.778	42.088	1.00	56.57	C
ATOM	2552	CB	THR	A	394	59.473	12.799	42.937	1.00	55.92	C
ATOM	2554	OG1	THR	A	394	60.456	13.427	42.112	1.00	54.95	O
ATOM	2556	CG2	THR	A	394	60.316	12.146	44.051	1.00	55.31	C
ATOM	2560	C	THR	A	394	57.925	10.738	42.984	1.00	56.54	C
ATOM	2561	O	THR	A	394	57.113	11.092	43.797	1.00	55.96	O
ATOM	2563	N	ALA	A	395	58.251	9.453	42.848	1.00	57.70	N
ATOM	2564	CA	ALA	A	395	57.638	8.413	43.686	1.00	58.38	C
ATOM	2566	CB	ALA	A	395	57.925	7.036	43.156	1.00	58.60	C
ATOM	2570	C	ALA	A	395	58.112	8.508	45.122	1.00	60.18	C
ATOM	2571	O	ALA	A	395	59.196	9.025	45.398	1.00	60.48	O
ATOM	2573	N	HIS	A	396	57.300	8.006	46.041	1.00	62.13	N
ATOM	2574	CA	HIS	A	396	57.701	7.974	47.432	1.00	63.98	C
ATOM	2576	CB	HIS	A	396	56.511	7.723	48.374	1.00	64.98	C
ATOM	2579	CG	HIS	A	396	56.808	8.051	49.807	1.00	67.58	C
ATOM	2580	ND1	HIS	A	396	57.407	9.239	50.191	1.00	68.28	N
ATOM	2582	CE1	HIS	A	396	57.581	9.230	51.506	1.00	70.33	C
ATOM	2584	NE2	HIS	A	396	57.101	8.090	51.990	1.00	70.58	N
ATOM	2586	CD2	HIS	A	396	56.617	7.332	50.947	1.00	70.45	C
ATOM	2588	C	HIS	A	396	58.787	6.903	47.539	1.00	64.38	C
ATOM	2589	O	HIS	A	396	58.811	5.953	46.730	1.00	65.07	O
ATOM	2591	N	ALA	A	397	59.718	7.099	48.478	1.00	64.69	N
ATOM	2592	CA	ALA	A	397	60.857	6.194	48.650	1.00	64.75	C
ATOM	2594	CB	ALA	A	397	61.914	6.774	49.523	1.00	65.08	C
ATOM	2598	C	ALA	A	397	60.335	4.955	49.265	1.00	65.23	C
ATOM	2599	O	ALA	A	397	59.335	4.978	50.000	1.00	65.93	O
ATOM	2601	N	GLY	A	398	60.983	3.854	48.929	1.00	65.61	N
ATOM	2602	CA	GLY	A	398	60.417	2.557	49.211	1.00	66.37	C
ATOM	2605	C	GLY	A	398	59.133	2.249	48.450	1.00	66.61	C
ATOM	2606	O	GLY	A	398	58.406	1.332	48.842	1.00	67.56	O
ATOM	2608	N	ALA	A	399	58.854	2.972	47.356	1.00	66.29	N
ATOM	2609	CA	ALA	A	399	57.878	2.494	46.373	1.00	66.12	C
ATOM	2611	CB	ALA	A	399	57.481	3.606	45.381	1.00	65.80	C
ATOM	2615	C	ALA	A	399	58.483	1.256	45.673	1.00	65.50	C
ATOM	2616	O	ALA	A	399	59.698	1.065	45.651	1.00	65.20	O
ATOM	2618	N	LYS	A	400	57.625	0.377	45.196	1.00	65.33	N
ATOM	2619	CA	LYS	A	400	58.072	−0.848	44.518	1.00	65.47	C
ATOM	2621	CB	LYS	A	400	57.428	−2.082	45.132	1.00	65.39	C
ATOM	2624	CG	LYS	A	400	57.992	−2.423	46.515	1.00	66.42	C
ATOM	2630	C	LYS	A	400	57.705	−0.688	43.044	1.00	65.09	C
ATOM	2631	O	LYS	A	400	56.561	−0.336	42.732	1.00	66.11	O
ATOM	2633	N	PHE	A	401	58.699	−0.878	42.168	1.00	63.74	N
ATOM	2634	CA	PHE	A	401	58.560	−0.753	40.731	1.00	62.36	C
ATOM	2636	CB	PHE	A	401	59.710	0.054	40.184	1.00	62.44	C
ATOM	2639	CG	PHE	A	401	59.883	1.398	40.808	1.00	63.52	C
ATOM	2640	CD1	PHE	A	401	58.787	2.176	41.202	1.00	63.93	C
ATOM	2642	CE1	PHE	A	401	58.994	3.437	41.767	1.00	64.70	C
ATOM	2644	CZ	PHE	A	401	60.298	3.955	41.891	1.00	63.13	C
ATOM	2646	CE2	PHE	A	401	61.367	3.224	41.464	1.00	62.81	C
ATOM	2648	CD2	PHE	A	401	61.167	1.944	40.923	1.00	63.99	C
ATOM	2650	C	PHE	A	401	58.709	−2.106	40.072	1.00	61.65	C
ATOM	2651	O	PHE	A	401	59.452	−2.968	40.621	1.00	62.75	O
ATOM	2653	N	PRO	A	402	58.121	−2.291	38.875	1.00	59.69	N
ATOM	2654	CA	PRO	A	402	58.587	−3.376	37.972	1.00	57.88	C
ATOM	2656	CB	PRO	A	402	57.463	−3.482	36.939	1.00	58.48	C
ATOM	2659	CG	PRO	A	402	56.849	−2.058	36.889	1.00	58.79	C
ATOM	2662	CD	PRO	A	402	57.010	−1.520	38.275	1.00	59.09	C
ATOM	2665	C	PRO	A	402	59.942	−2.978	37.351	1.00	56.59	C
ATOM	2666	O	PRO	A	402	59.985	−2.318	36.344	1.00	55.60	O
ATOM	2667	N	ILE	A	403	61.029	−3.376	37.999	1.00	55.79	N
ATOM	2668	CA	ILE	A	403	62.403	−2.962	37.650	1.00	55.33	C
ATOM	2670	CB	ILE	A	403	63.463	−3.887	38.367	1.00	55.76	C
ATOM	2672	CG1	ILE	A	403	63.390	−3.790	39.909	1.00	56.03	C
ATOM	2675	CD1	ILE	A	403	63.737	−2.428	40.498	1.00	55.85	C
ATOM	2679	CG2	ILE	A	403	64.899	−3.579	37.888	1.00	56.38	C
ATOM	2683	C	ILE	A	403	62.668	−2.993	36.145	1.00	54.38	C
ATOM	2684	O	ILE	A	403	62.990	−1.961	35.560	1.00	53.73	O
ATOM	2686	N	LYS	A	404	62.455	−4.173	35.543	1.00	53.63	N
ATOM	2687	CA	LYS	A	404	62.794	−4.474	34.134	1.00	52.99	C
ATOM	2689	CB	LYS	A	404	62.629	−5.964	33.851	1.00	52.71	C
ATOM	2692	CG	LYS	A	404	63.702	−6.801	34.540	1.00	54.23	C
ATOM	2695	CD	LYS	A	404	63.345	−8.306	34.508	1.00	56.00	C
ATOM	2698	CE	LYS	A	404	64.416	−9.240	35.160	1.00	57.15	C
ATOM	2701	NZ	LYS	A	404	65.179	−10.091	34.197	1.00	57.27	N
ATOM	2705	C	LYS	A	404	62.063	−3.650	33.061	1.00	51.78	C
ATOM	2706	O	LYS	A	404	62.398	−3.748	31.892	1.00	51.95	O
ATOM	2708	N	TRP	A	405	61.064	−2.877	33.463	1.00	50.55	N
ATOM	2709	CA	TRP	A	405	60.387	−1.874	32.646	1.00	49.89	C
ATOM	2711	CB	TRP	A	405	58.868	−1.993	32.841	1.00	48.43 C
ATOM	2714	CG	TRP	A	405	58.321	−3.029	32.076	1.00	46.94	C
ATOM	2715	CD1	TRP	A	405	57.691	−2.891	30.900	1.00	46.16	C
ATOM	2717	NE1	TRP	A	405	57.303	−4.114	30.431	1.00	46.67	N
ATOM	2719	CE2	TRP	A	405	57.706	−5.076	31.320	1.00	47.09	C
ATOM	2720	CD2	TRP	A	405	58.354	−4.417	32.373	1.00	46.79	C
ATOM	2721	CE3	TRP	A	405	58.858	−5.186	33.438	1.00	46.32	C
ATOM	2723	CZ3	TRP	A	405	58.701	−6.510	33.414	1.00	44.90	C
ATOM	2725	CH2	TRP	A	405	58.063	−7.135	32.354	1.00	45.72	C
ATOM	2727	CZ2	TRP	A	405	57.558	−6.443	31.292	1.00	44.52	C
ATOM	2729	C	TRP	A	405	60.716	−0.479	33.046	1.00	49.55	C
ATOM	2730	O	TRP	A	405	60.271	0.426	32.377	1.00	50.62	O
ATOM	2732	N	THR	A	406	61.427	−0.287	34.153	1.00	49.74	N
ATOM	2733	CA	THR	A	406	61.627	1.037	34.747	1.00	49.85	C
ATOM	2735	CB	THR	A	406	61.574	0.931	36.291	1.00	49.94	C
ATOM	2737	OG1	THR	A	406	60.329	0.335	36.706	1.00	48.47	O
ATOM	2739	CG2	THR	A	406	61.584	2.322	36.916	1.00	49.29	C
ATOM	2743	C	THR	A	406	62.959	1.659	34.297	1.00	49.97	C
ATOM	2744	O	THR	A	406	63.996	0.948	34.302	1.00	50.67	O
ATOM	2746	N	ALA	A	407	62.919	2.960	33.983	1.00	49.61	N
ATOM	2747	CA	ALA	A	407	64.068	3.733	33.448	1.00	49.64	C
ATOM	2749	CB	ALA	A	407	63.591	5.048	32.847	1.00	49.55	C
ATOM	2753	C	ALA	A	407	65.077	4.079	34.501	1.00	49.68	C
ATOM	2754	O	ALA	A	407	64.675	4.253	35.628	1.00	50.21	O
ATOM	2756	N	PRO	A	408	66.351	4.300	34.150	1.00	50.27	N
ATOM	2757	CA	PRO	A	408	67.398	4.433	35.152	1.00	50.64	C
ATOM	2759	CB	PRO	A	408	68.669	4.651	34.313	1.00	50.13	C
ATOM	2762	CG	PRO	A	408	68.368	3.978	33.090	1.00	50.42	C
ATOM	2765	CD	PRO	A	408	66.943	4.465	32.811	1.00	50.69	C
ATOM	2768	C	PRO	A	408	67.207	5.546	36.169	1.00	51.16	C
ATOM	2769	O	PRO	A	408	67.391	5.287	37.369	1.00	52.10	O
ATOM	2770	N	GLU	A	409	66.848	6.750	35.724	1.00	51.37	N
ATOM	2771	CA	GLU	A	409	66.573	7.860	36.663	1.00	51.89	C
ATOM	2773	CB	GLU	A	409	66.367	9.212	35.970	1.00	52.46	C
ATOM	2776	CG	GLU	A	409	65.099	9.363	35.098	1.00	54.26	C
ATOM	2779	CD	GLU	A	409	65.120	8.562	33.809	1.00	52.61	C
ATOM	2780	OE1	GLU	A	409	66.165	7.944	33.500	1.00	54.56	O
ATOM	2781	OE2	GLU	A	409	64.099	8.550	33.123	1.00	50.79	O
ATOM	2782	C	GLU	A	409	65.403	7.583	37.610	1.00	51.83	C
ATOM	2783	O	GLU	A	409	65.378	8.126	38.728	1.00	52.36	O
ATOM	2785	N	SER	A	410	64.453	6.741	37.178	1.00	51.16	N
ATOM	2786	CA	SER	A	410	63.358	6.301	38.052	1.00	50.45	C
ATOM	2788	CB	SER	A	410	62.209	5.688	37.254	1.00	50.22	C
ATOM	2791	OG	SER	A	410	61.816	6.484	36.142	1.00	48.58	O
ATOM	2793	C	SER	A	410	63.895	5.319	39.092	1.00	50.93	C
ATOM	2794	O	SER	A	410	63.574	5.477	40.282	1.00	52.03	O
ATOM	2796	N	LEU	A	411	64.735	4.345	38.691	1.00	50.30	N
ATOM	2797	CA	LEU	A	411	65.378	3.423	39.685	1.00	50.08	C
ATOM	2799	CB	LEU	A	411	66.111	2.254	39.022	1.00	50.19	C
ATOM	2802	CG	LEU	A	411	65.339	1.288	38.090	1.00	51.68	C
ATOM	2804	CD1	LEU	A	411	66.281	0.454	37.196	1.00	51.31	C
ATOM	2808	CD2	LEU	A	411	64.487	0.375	38.863	1.00	52.17	C
ATOM	2812	C	LEU	A	411	66.340	4.107	40.680	1.00	49.77	C
ATOM	2813	O	LEU	A	411	66.444	3.651	41.796	1.00	50.26	O
ATOM	2815	N	ALA	A	412	67.032	5.186	40.304	1.00	49.48	N
ATOM	2816	CA	ALA	A	412	68.003	5.827	41.221	1.00	49.44	C
ATOM	2818	CB	ALA	A	412	69.140	6.443	40.459	1.00	49.50	C
ATOM	2822	C	ALA	A	412	67.342	6.873	42.088	1.00	49.35	C
ATOM	2823	O	ALA	A	412	67.481	6.859	43.302	1.00	50.56	O
ATOM	2825	N	TYR	A	413	66.589	7.762	41.459	1.00	49.00	N
ATOM	2826	CA	TYR	A	413	66.062	8.963	42.102	1.00	48.50	C
ATOM	2828	CB	TYR	A	413	66.554	10.140	41.287	1.00	47.26	C
ATOM	2831	CG	TYR	A	413	68.047	10.061	41.059	1.00	47.26	C
ATOM	2832	CD1	TYR	A	413	68.926	10.069	42.138	1.00	46.98	C
ATOM	2834	CE1	TYR	A	413	70.315	10.033	41.940	1.00	46.70	C
ATOM	2836	CZ	TYR	A	413	70.831	9.951	40.643	1.00	45.93	C
ATOM	2837	OH	TYR	A	413	72.211	9.868	40.478	1.00	47.65	O
ATOM	2839	CE2	TYR	A	413	69.979	9.932	39.559	1.00	44.66	C
ATOM	2841	CD2	TYR	A	413	68.595	9.973	39.766	1.00	46.15	C
ATOM	2843	C	TYR	A	413	64.539	9.007	42.228	1.00	48.63	C
ATOM	2844	O	TYR	A	413	63.981	10.026	42.636	1.00	48.32	O
ATOM	2846	N	ASN	A	414	63.859	7.916	41.865	1.00	49.52	N
ATOM	2847	CA	ASN	A	414	62.378	7.903	41.738	1.00	50.04	C
ATOM	2849	CB	ASN	A	414	61.698	7.874	43.109	1.00	49.50	C
ATOM	2852	CG	ASN	A	414	62.299	6.888	44.014	1.00	48.81	C
ATOM	2853	OD1	ASN	A	414	62.072	5.691	43.893	1.00	50.48	O
ATOM	2854	ND2	ASN	A	414	63.103	7.373	44.942	1.00	51.56	N
ATOM	2857	C	ASN	A	414	61.799	9.058	40.889	1.00	50.92	C
ATOM	2858	O	ASN	A	414	60.690	9.510	41.141	1.00	50.65	O
ATOM	2860	N	LYS	A	415	62.540	9.510	39.885	1.00	51.77	N
ATOM	2861	CA	LYS	A	415	62.018	10.527	38.985	1.00	53.04	C
ATOM	2863	CB	LYS	A	415	63.106	11.543	38.574	1.00	52.90	C
ATOM	2866	CG	LYS	A	415	63.119	12.820	39.508	1.00	55.05	C
ATOM	2869	CD	LYS	A	415	64.539	13.405	39.779	1.00	56.64	C
ATOM	2872	CE	LYS	A	415	65.111	14.352	38.625	1.00	60.50	C
ATOM	2875	NZ	LYS	A	415	66.036	13.655	37.638	1.00	63.58	N
ATOM	2879	C	LYS	A	415	61.292	9.797	37.823	1.00	51.91	C
ATOM	2880	O	LYS	A	415	61.906	9.052	37.065	1.00	51.90	O
ATOM	2882	N	PHE	A	416	59.969	9.991	37.768	1.00	51.15	N
ATOM	2883	CA	PHE	A	416	59.110	9.602	36.655	1.00	50.52	C
ATOM	2885	CB	PHE	A	416	57.874	8.911	37.165	1.00	50.24	C
ATOM	2888	CG	PHE	A	416	58.193	7.624	37.814	1.00	50.01	C
ATOM	2889	CD1	PHE	A	416	58.714	7.584	39.126	1.00	51.45	C
ATOM	2891	CE1	PHE	A	416	59.065	6.383	39.706	1.00	48.81	C
ATOM	2893	CZ	PHE	A	416	58.908	5.228	38.983	1.00	48.80	C
ATOM	2895	CE2	PHE	A	416	58.432	5.268	37.704	1.00	49.22	C
ATOM	2897	CD2	PHE	A	416	58.095	6.463	37.115	1.00	48.43	C
ATOM	2899	C	PHE	A	416	58.755	10.818	35.854	1.00	50.13	C
ATOM	2900	O	PHE	A	416	58.834	11.914	36.380	1.00	51.13	O
ATOM	2902	N	SER	A	417	58.439	10.599	34.568	1.00	49.55	N
ATOM	2903	CA	SER	A	417	58.114	11.629	33.547	1.00	48.43	C
ATOM	2905	CB	SER	A	417	59.363	12.349	33.188	1.00	47.84	C
ATOM	2908	OG	SER	A	417	60.183	11.494	32.429	1.00	48.45	O
ATOM	2910	C	SER	A	417	57.550	10.971	32.247	1.00	48.41	C
ATOM	2911	O	SER	A	417	57.387	9.737	32.136	1.00	48.30	O
ATOM	2913	N	ILE	A	418	57.257	11.772	31.242	1.00	48.13	N
ATOM	2914	CA	ILE	A	418	56.745	11.189	29.996	1.00	48.24	C
ATOM	2916	CB	ILE	A	418	56.293	12.302	29.062	1.00	48.42	C
ATOM	2918	CG1	ILE	A	418	55.074	13.010	29.686	1.00	50.54	C
ATOM	2921	CD1	ILE	A	418	55.021	14.519	29.436	1.00	53.60	C
ATOM	2925	CG2	ILE	A	418	55.901	11.743	27.689	1.00	48.57	C
ATOM	2929	C	ILE	A	418	57.828	10.263	29.393	1.00	47.77	C
ATOM	2930	O	ILE	A	418	57.569	9.106	29.032	1.00	47.92	O
ATOM	2932	N	LYS	A	419	59.033	10.817	29.332	1.00	46.76	N
ATOM	2933	CA	LYS	A	419	60.266	10.136	29.009	1.00	45.78	C
ATOM	2935	CB	LYS	A	419	61.442	11.062	29.322	1.00	44.69	C
ATOM	2938	CG	LYS	A	419	62.007	11.750	28.133	1.00	43.87	C
ATOM	2941	CD	LYS	A	419	61.036	12.446	27.166	1.00	41.50	C
ATOM	2944	CE	LYS	A	419	61.699	12.738	25.833	1.00	41.17	C
ATOM	2947	NZ	LYS	A	419	60.662	13.163	24.853	1.00	42.34	N
ATOM	2951	C	LYS	A	419	60.480	8.800	29.690	1.00	46.43	C
ATOM	2952	0	LYS	A	419	60.977	7.865	29.045	1.00	45.91	O
ATOM	2954	N	SER	A	420	60.122	8.700	30.968	1.00	46.65	N
ATOM	2955	CA	SER	A	420	60.267	7.426	31.662	1.00	47.64	C
ATOM	2957	CB	SER	A	420	60.252	7.623	33.183	1.00	47.41	C
ATOM	2960	OG	SER	A	420	58.940	7.729	33.718	1.00	49.07	O
ATOM	2962	C	SER	A	420	59.228	6.379	31.117	1.00	47.84	C
ATOM	2963	0	SER	A	420	59.525	5.219	30.984	1.00	48.93	O
ATOM	2965	N	ASP	A	421	58.041	6.812	30.748	1.00	48.57	N
ATOM	2966	CA	ASP	A	421	57.112	5.984	29.952	1.00	48.99	C
ATOM	2968	CB	ASP	A	421	55.701	6.662	29.830	1.00	49.45	C
ATOM	2971	CG	ASP	A	421	54.994	6.807	31.162	1.00	51.17	C
ATOM	2972	OD1	ASP	A	421	55.559	6.471	32.249	1.00	51.48	O
ATOM	2973	OD2	ASP	A	421	53.837	7.259	31.211	1.00	55.51	O
ATOM	2974	C	ASP	A	421	57.601	5.669	28.530	1.00	48.39	C
ATOM	2975	O	ASP	A	421	57.162	4.668	27.952	1.00	48.16	O
ATOM	2977	N	VAL	A	422	58.411	6.555	27.940	1.00	47.58	N
ATOM	2978	CA	VAL	A	422	59.000	6.284	26.629	1.00	47.40	C
ATOM	2980	CB	VAL	A	422	59.846	7.480	26.068	1.00	47.85	C
ATOM	2982	CG1	VAL	A	422	60.595	7.094	24.765	1.00	47.45	C
ATOM	2986	CG2	VAL	A	422	58.959	8.756	25.827	1.00	47.11	C
ATOM	2990	C	VAL	A	422	59.865	5.040	26.783	1.00	47.21	C
ATOM	2991	O	VAL	A	422	59.702	4.062	26.026	1.00	47.55	O
ATOM	2993	N	TRP	A	423	60.729	5.061	27.802	1.00	46.57	N
ATOM	2994	CA	TRP	A	423	61.530	3.895	28.192	1.00	45.98	C
ATOM	2996	CB	TRP	A	423	62.315	4.194	29.492	1.00	46.04	C
ATOM	2999	CG	TRP	A	423	63.273	3.090	29.897	1.00	47.36	C
ATOM	3000	CD1	TRP	A	423	62.929	1.889	30.432	1.00	47.55	C
ATOM	3002	NE1	TRP	A	423	64.052	1.153	30.668	1.00	48.29	N
ATOM	3004	CE2	TRP	A	423	65.153	1.846	30.261	1.00	46.14	C
ATOM	3005	CD2	TRP	A	423	64.704	3.073	29.767	1.00	46.11	C
ATOM	3006	CE3	TRP	A	423	65.652	3.985	29.303	1.00	47.79	C
ATOM	3008	CZ3	TRP	A	423	67.016	3.624	29.337	1.00	47.76	C
ATOM	3010	CH2	TRP	A	423	67.418	2.364	29.816	1.00	47.57	C
ATOM	3012	CZ2	TRP	A	423	66.506	1.470	30.276	1.00	46.69	C
ATOM	3014	C	TRP	A	423	60.692	2.604	28.297	1.00	45.21	C
ATOM	3015	O	TRP	A	423	60.979	1.595	27.654	1.00	43.59	O
ATOM	3017	N	ALA	A	424	59.642	2.709	29.101	1.00	45.77	N
ATOM	3018	CA	ALA	A	424	58.621	1.654	29.322	1.00	46.14	C
ATOM	3020	CB	ALA	A	424	57.497	2.209	30.182	1.00	46.41	C
ATOM	3024	C	ALA	A	424	58.011	1.084	28.035	1.00	46.30	C
ATOM	3025	O	ALA	A	424	57.834	−0.136	27.876	1.00	43.97	O
ATOM	3027	N	PHE	A	425	57.683	2.015	27.139	1.00	47.45	N
ATOM	3028	CA	PHE	A	425	57.122	1.689	25.828	1.00	48.30	C
ATOM	3030	CB	PHE	A	425	56.640	2.956	25.073	1.00	48.93	C
ATOM	3033	CG	PHE	A	425	56.116	2.656	23.715	1.00	50.33	C
ATOM	3034	CD1	PHE	A	425	54.797	2.214	23.550	1.00	50.66	C
ATOM	3036	CE1	PHE	A	425	54.303	1.848	22.258	1.00	50.15	C
ATOM	3038	CZ	PHE	A	425	55.157	1.935	21.131	1.00	51.09	C
ATOM	3040	CE2	PHE	A	425	56.506	2.345	21.293	1.00	50.74	C
ATOM	3042	CD2	PHE	A	425	56.974	2.705	22.591	1.00	51.55	C
ATOM	3044	C	PHE	A	425	58.144	0.879	25.018	1.00	47.58	C
ATOM	3045	O	PHE	A	425	57.793	−0.164	24.448	1.00	47.13	O
ATOM	3047	N	GLY	A	426	59.395	1.344	25.007	1.00	47.25	N
ATOM	3048	CA	GLY	A	426	60.474	0.628	24.308	1.00	47.10	C
ATOM	3051	C	GLY	A	426	60.579	−0.851	24.701	1.00	46.27	C
ATOM	3052	O	GLY	A	426	60.798	−1.720	23.857	1.00	45.66	O
ATOM	3054	N	VAL	A	427	60.405	−1.110	25.993	1.00	45.34	N
ATOM	3055	CA	VAL	A	427	60.470	−2.460	26.545	1.00	45.21	C
ATOM	3057	CB	VAL	A	427	60.648	−2.402	28.125	1.00	45.04	C
ATOM	3059	CG1	VAL	A	427	60.593	−3.814	28.824	1.00	45.31	C
ATOM	3063	CG2	VAL	A	427	61.955	−1.732	28.445	1.00	44.03	C
ATOM	3067	C	VAL	A	427	59.263	−3.311	26.097	1.00	44.99	C
ATOM	3068	O	VAL	A	427	59.430	−4.486	25.729	1.00	45.67	O
ATOM	3070	N	LEU	A	428	58.073	−2.719	26.171	1.00	44.78	N
ATOM	3071	CA	LEU	A	428	56.855	−3.254	25.548	1.00	44.69	C
ATOM	3073	CB	LEU	A	428	55.670	−2.289	25.785	1.00	45.09	C
ATOM	3076	CG	LEU	A	428	54.375	−2.388	24.956	1.00	45.86	C
ATOM	3078	CD1	LEU	A	428	53.662	−3.677	25.258	1.00	48.58	C
ATOM	3082	CD2	LEU	A	428	53.466	−1.224	25.226	1.00	45.75	C
ATOM	3086	C	LEU	A	428	57.012	−3.612	24.035	1.00	44.14	C
ATOM	3087	O	LEU	A	428	56.494	−4.647	23.593	1.00	42.31	O
ATOM	3089	N	LEU	A	429	57.711	−2.777	23.257	1.00	43.88	N
ATOM	3090	CA	LEU	A	429	58.003	−3.154	21.871	1.00	44.20	C
ATOM	3092	CB	LEU	A	429	58.809	−2.114	21.096	1.00	43.64	C
ATOM	3095	CG	LEU	A	429	58.079	−0.832	20.655	1.00	45.00	C
ATOM	3097	CD1	LEU	A	429	59.048	0.175	19.948	1.00	43.66	C
ATOM	3101	CD2	LEU	A	429	56.826	−1.102	19.746	1.00	44.75	C
ATOM	3105	C	LEU	A	429	58.757	−4.463	21.889	1.00	44.59	C
ATOM	3106	O	LEU	A	429	58.407	−5.379	21.137	1.00	45.60	O
ATOM	3108	N	TRP	A	430	59.743	−4.567	22.783	1.00	44.42	N
ATOM	3109	CA	TRP	A	430	60.551	−5.770	22.916	1.00	44.32	C
ATOM	3111	CB	TRP	A	430	61.713	−5.537	23.917	1.00	43.34	C
ATOM	3114	CG	TRP	A	430	62.747	−6.578	23.849	1.00	42.11	C
ATOM	3115	CD1	TRP	A	430	63.896	−6.518	23.155	1.00	41.67	C
ATOM	3117	NE1	TRP	A	430	64.586	−7.698	23.290	1.00	41.49	N
ATOM	3119	CE2	TRP	A	430	63.873	−8.547	24.085	1.00	39.79	C
ATOM	3120	CD2	TRP	A	430	62.704	−7.872	24.459	1.00	40.36	C
ATOM	3121	CE3	TRP	A	430	61.782	−8.541	25.275	1.00	40.59	C
ATOM	3123	CZ3	TRP	A	430	62.093	−9.840	25.723	1.00	41.66	C
ATOM	3125	CH2	TRP	A	430	63.266	−10.467	25.335	1.00	41.06	C
ATOM	3127	CZ2	TRP	A	430	64.169	−9.837	24.514	1.00	40.31	C
ATOM	3129	C	TRP	A	430	59.660	−6.980	23.286	1.00	44.66	C
ATOM	3130	O	TRP	A	430	59.860	−8.097	22.781	1.00	42.95	O
ATOM	3132	N	GLU	A	431	58.653	−6.737	24.133	1.00	45.66	N
ATOM	3133	CA	GLU	A	431	57.661	−7.788	24.447	1.00	46.28	C
ATOM	3135	CB	GLU	A	431	56.694	−7.365	25.549	1.00	45.74	C
ATOM	3138	CG	GLU	A	431	57.320	−6.917	26.868	1.00	46.68	C
ATOM	3141	CD	GLU	A	431	56.252	−6.568	27.912	1.00	48.88	C
ATOM	3142	OE1	GLU	A	431	55.767	−7.497	28.625	1.00	50.05	O
ATOM	3143	OE2	GLU	A	431	55.862	−5.351	27.986	1.00	53.25	O
ATOM	3144	C	GLU	A	431	56.868	−8.210	23.222	1.00	46.59	C
ATOM	3145	O	GLU	A	431	56.596	−9.390	23.051	1.00	48.89	O
ATOM	3147	N	ILE	A	432	56.501	−7.256	22.377	1.00	46.79	N
ATOM	3148	CA	ILE	A	432	55.615	−7.497	21.235	1.00	47.22	C
ATOM	3150	CB	ILE	A	432	55.051	−6.126	20.679	1.00	47.19	C
ATOM	3152	CG1	ILE	A	432	53.999	−5.578	21.647	1.00	47.56	C
ATOM	3155	CD1	ILE	A	432	53.571	−4.143	21.409	1.00	47.69	C
ATOM	3159	CG2	ILE	A	432	54.388	−6.299	19.338	1.00	47.88	C
ATOM	3163	C	ILE	A	432	56.387	−8.263	20.189	1.00	47.72	C
ATOM	3164	O	ILE	A	432	55.940	−9.291	19.720	1.00	47.80	O
ATOM	3166	N	ALA	A	433	57.560	−7.743	19.855	1.00	49.10	N
ATOM	3167	CA	ALA	A	433	58.541	−8.380	18.943	1.00	50.08	C
ATOM	3169	CB	ALA	A	433	59.800	−7.538	18.876	1.00	50.50	C
ATOM	3173	C	ALA	A	433	58.954	−9.799	19.243	1.00	50.16	C
ATOM	3174	O	ALA	A	433	59.299	−10.498	18.327	1.00	51.09	O
ATOM	3176	N	THR	A	434	58.933	−10.210	20.507	1.00	51.09	N
ATOM	3177	CA	THR	A	434	59.255	−11.600	20.930	1.00	51.38	C
ATOM	3179	CB	THR	A	434	60.117	−11.546	22.217	1.00	51.73	C
ATOM	3181	OG1	THR	A	434	59.392	−10.824	23.222	1.00	53.77	O
ATOM	3183	CG2	THR	A	434	61.451	−10.758	22.003	1.00	51.31	C
ATOM	3187	C	THR	A	434	58.050	−12.461	21.247	1.00	51.17	C
ATOM	3188	O	THR	A	434	58.212	−13.584	21.753	1.00	51.41	O
ATOM	3190	N	TYR	A	435	56.848	−11.948	21.010	1.00	51.51	N
ATOM	3191	CA	TYR	A	435	55.588	−12.628	21.455	1.00	51.75	C
ATOM	3193	CB	TYR	A	435	55.271	−13.902	20.633	1.00	50.84	C
ATOM	3196	CG	TYR	A	435	55.007	−13.606	19.196	1.00	49.66	C
ATOM	3197	CD1	TYR	A	435	56.054	−13.454	18.293	1.00	49.18	C
ATOM	3199	CE1	TYR	A	435	55.817	−13.172	16.960	1.00	48.20	C
ATOM	3201	CZ	TYR	A	435	54.533	−13.045	16.530	1.00	48.92	C
ATOM	3202	OH	TYR	A	435	54.287	−12.748	15.253	1.00	50.40	O
ATOM	3204	CE2	TYR	A	435	53.474	−13.177	17.389	1.00	49.60	C
ATOM	3206	CD2	TYR	A	435	53.719	−13.448	18.731	1.00	49.74	C
ATOM	3208	C	TYR	A	435	55.595	−12.949	22.942	1.00	51.79	C
ATOM	3209	O	TYR	A	435	55.373	−14.099	23.349	1.00	50.77	O
ATOM	3211	N	GLY	A	436	55.907	−11.918	23.718	1.00	52.32	N
ATOM	3212	CA	GLY	A	436	55.778	−11.971	25.161	1.00	53.64	C
ATOM	3215	C	GLY	A	436	56.827	−12.726	25.962	1.00	54.48	C
ATOM	3216	O	GLY	A	436	56.488	−13.339	26.971	1.00	54.70	O
ATOM	3218	N	MET	A	437	58.092	−12.674	25.541	1.00	55.41	N
ATOM	3219	CA	MET	A	437	59.222	−13.059	26.426	1.00	56.42	C
ATOM	3221	CB	MET	A	437	60.539	−13.157	25.647	1.00	56.49	C
ATOM	3224	CG	MET	A	437	60.745	−14.482	24.876	1.00	59.17	C
ATOM	3227	SD	MET	A	437	62.386	−14.383	23.998	1.00	62.41	S
ATOM	3228	CE	MET	A	437	63.728	−15.039	25.513	1.00	64.10	C
ATOM	3232	C	MET	A	437	59.373	−12.019	27.543	1.00	54.60	C
ATOM	3233	O	MET	A	437	59.088	−10.826	27.324	1.00	54.63	O
ATOM	3235	N	SER	A	438	59.796	−12.469	28.728	1.00	53.13	N
ATOM	3236	CA	SER	A	438	60.126	−11.562	29.839	1.00	52.40	C
ATOM	3238	CB	SER	A	438	60.311	−12.296	31.139	1.00	52.37	C
ATOM	3241	OG	SER	A	438	59.146	−13.010	31.450	1.00	56.00	O
ATOM	3243	C	SER	A	438	61.439	−10.849	29.566	1.00	51.38	C
ATOM	3244	O	SER	A	438	62.426	−11.516	29.142	1.00	51.57	O
ATOM	3246	N	PRO	A	439	61.489	−9.535	29.806	1.00	49.65	N
ATOM	3247	CA	PRO	A	439	62.725	−8.768	29.564	1.00	48.82	C
ATOM	3249	CB	PRO	A	439	62.327	−7.312	29.846	1.00	48.91	C
ATOM	3252	CG	PRO	A	439	60.891	−7.297	30.014	1.00	49.15	C
ATOM	3255	CD	PRO	A	439	60.384	−8.665	30.211	1.00	49.33	C
ATOM	3258	C	PRO	A	439	63.966	−9.199	30.380	1.00	48.32	C
ATOM	3259	O	PRO	A	439	63.831	−9.837	31.423	1.00	47.61	O
ATOM	3260	N	TYR	A	440	65.147	−8.864	29.833	1.00	47.63	N
ATOM	3261	CA	TYR	A	440	66.470	−9.221	30.382	1.00	46.71	C
ATOM	3263	CB	TYR	A	440	66.863	−8.267	31.536	1.00	46.57	C
ATOM	3266	CG	TYR	A	440	66.886	−6.885	31.098	1.00	44.68	C
ATOM	3267	CD1	TYR	A	440	67.974	−6.396	30.403	1.00	46.62	C
ATOM	3269	CE1	TYR	A	440	68.027	−5.047	29.980	1.00	47.17	C
ATOM	3271	CZ	TYR	A	440	66.919	−4.220	30.203	1.00	45.95	C
ATOM	3272	OH	TYR	A	440	66.935	−2.965	29.729	1.00	47.49	O
ATOM	3274	CE2	TYR	A	440	65.812	−4.686	30.864	1.00	45.22	C
ATOM	3276	CD2	TYR	A	440	65.797	−6.049	31.310	1.00	46.32	C
ATOM	3278	C	TYR	A	440	66.493	−10.643	30.840	1.00	44.68	C
ATOM	3279	O	TYR	A	440	66.759	−10.886	31.995	1.00	42.62	O
ATOM	3281	N	PRO	A	441	66.203	−11.568	29.927	1.00	44.78	N
ATOM	3282	CA	PRO	A	441	65.956	−12.991	30.288	1.00	45.49	C
ATOM	3284	CB	PRO	A	441	65.764	−13.703	28.939	1.00	44.71	C
ATOM	3287	CG	PRO	A	441	65.906	−12.720	27.900	1.00	43.56	C
ATOM	3290	CD	PRO	A	441	66.163	−11.371	28.474	1.00	44.55	C
ATOM	3293	C	PRO	A	441	67.132	−13.588	31.003	1.00	46.24	C
ATOM	3294	O	PRO	A	441	68.257	−13.486	30.507	1.00	46.98	O
ATOM	3295	N	GLY	A	442	66.898	−14.083	32.201	1.00	47.65	N
ATOM	3296	CA	GLY	A	442	67.916	−14.854	32.924	1.00	49.12	C
ATOM	3299	C	GLY	A	442	68.727	−14.030	33.894	1.00	50.64	C
ATOM	3300	O	GLY	A	442	69.505	−14.603	34.649	1.00	51.14	O
ATOM	3302	N	ILE	A	443	68.511	−12.711	33.901	1.00	52.0	N
ATOM	3303	CA	ILE	A	443	69.234	−11.765	34.724	1.00	53.8	C
ATOM	3305	CB	ILE	A	443	69.487	−10.475	33.908	1.00	53.6	C
ATOM	3307	CG1	ILE	A	443	70.501	−10.793	32.808	1.00	54.1	C
ATOM	3310	CD1	ILE	A	443	70.717	−9.696	31.838	1.00	54.3	C
ATOM	3314	CG2	ILE	A	443	69.945	−9.274	34.808	1.00	53.6	C
ATOM	3318	C	ILE	A	443	68.414	−11.447	35.974	1.00	54.9	C
ATOM	3319	O	ILE	A	443	67.226	−11.138	35.862	1.00	55.9	O
ATOM	3321	N	ASP	A	444	69.055	−11.498	37.148	1.00	56.0	N
ATOM	3322	CA	ASP	A	444	68.446	−11.029	38.413	1.00	56.7	C
ATOM	3324	CB	ASP	A	444	69.280	−11.414	39.667	1.00	57.8	C
ATOM	3327	CG	ASP	A	444	70.776	−10.879	39.617	1.00	62.5	C
ATOM	3328	OD1	ASP	A	444	71.319	−10.611	38.473	1.00	66.8	O
ATOM	3329	OD2	ASP	A	444	71.489	−10.731	40.670	1.00	65.1	O
ATOM	3330	C	ASP	A	444	68.233	−9.512	38.407	1.00	56.44	C
ATOM	3331	O	ASP	A	444	69.109	−8.750	37.955	1.00	55.83	O
ATOM	3333	N	LEU	A	445	67.073	−9.101	38.942	1.00	55.87	N
ATOM	3334	CA	LEU	A	445	66.749	−7.690	39.215	1.00	55.54	C
ATOM	3336	CB	LEU	A	445	65.589	−7.584	40.190	1.00	55.50	C
ATOM	3339	CG	LEU	A	445	64.288	−8.311	39.969	1.00	56.17	C
ATOM	3341	CD1	LEU	A	445	63.266	−7.790	41.002	1.00	55.87	C
ATOM	3345	CD2	LEU	A	445	63.821	−8.150	38.519	1.00	56.83	C
ATOM	3349	C	LEU	A	445	67.872	−6.862	39.831	1.00	55.12	C
ATOM	3350	O	LEU	A	445	68.017	−5.702	39.516	1.00	55.02	O
ATOM	3352	N	SER	A	446	68.617	−7.475	40.741	1.00	54.92	N
ATOM	3353	CA	SER	A	446	69.707	−6.818	41.461	1.00	54.79	C
ATOM	3355	CB	SER	A	446	70.156	−7.709	42.625	1.00	54.76	C
ATOM	3358	OG	SER	A	446	70.105	−9.061	42.203	1.00	56.56	O
ATOM	3360	C	SER	A	446	70.933	−6.446	40.619	1.00	54.57	C
ATOM	3361	O	SER	A	446	71.752	−5.686	41.109	1.00	54.74	O
ATOM	3363	N	GLN	A	447	71.082	−6.979	39.396	1.00	54.00	N
ATOM	3364	CA	GLN	A	447	72.150	−6.504	38.467	1.00	53.08	C
ATOM	3366	CB	GLN	A	447	72.994	−7.687	37.996	1.00	52.87	C
ATOM	3369	CG	GLN	A	447	73.694	−8.352	39.212	1.00	52.82	C
ATOM	3372	CD	GLN	A	447	74.741	−9.404	38.852	1.00	52.72	C
ATOM	3373	OE1	GLN	A	447	75.873	−9.059	38.407	1.00	49.36	O
ATOM	3374	NE2	GLN	A	447	74.397	−10.690	39.091	1.00	49.26	N
ATOM	3377	C	GLN	A	447	71.708	−5.553	37.322	1.00	52.34	C
ATOM	3378	O	GLN	A	447	72.546	−4.864	36.739	1.00	52.85	O
ATOM	3380	N	VAL	A	448	70.409	−5.422	37.095	1.00	51.23	N
ATOM	3381	CA	VAL	A	448	69.886	−4.681	35.952	1.00	50.51	C
ATOM	3383	CB	VAL	A	448	68.348	−4.711	35.905	1.00	49.82	C
ATOM	3385	CG1	VAL	A	448	67.820	−3.814	34.810	1.00	50.00	C
ATOM	3389	CG2	VAL	A	448	67.862	−6.132	35.644	1.00	49.15	C
ATOM	3393	C	VAL	A	448	70.428	−3.254	35.888	1.00	49.77	C
ATOM	3394	O	VAL	A	448	70.989	−2.881	34.885	1.00	49.91	O
ATOM	3396	N	TYR	A	449	70.315	−2.481	36.956	1.00	49.39	N
ATOM	3397	CA	TYR	A	449	70.724	−1.048	36.922	1.00	49.55	C
ATOM	3399	CB	TYR	A	449	70.418	−0.261	38.229	1.00	47.59	C
ATOM	3402	CG	TYR	A	449	70.910	1.191	38.208	1.00	47.42	C
ATOM	3403	CD1	TYR	A	449	72.234	1.511	38.549	1.00	44.15	C
ATOM	3405	CE1	TYR	A	449	72.701	2.803	38.502	1.00	43.51	C
ATOM	3407	CZ	TYR	A	449	71.847	3.862	38.124	1.00	44.96	C
ATOM	3408	OH	TYR	A	449	72.346	5.196	38.116	1.00	44.92	O
ATOM	3410	CE2	TYR	A	449	70.527	3.579	37.794	1.00	43.62	C
ATOM	3412	CD2	TYR	A	449	70.063	2.247	37.842	1.00	45.18	C
ATOM	3414	C	TYR	A	449	72.190	−0.953	36.566	1.00	50.41	C
ATOM	3415	O	TYR	A	449	72.508	−0.295	35.603	1.00	51.50	O
ATOM	3417	N	GLU	A	450	73.068	−1.611	37.316	1.00	51.84	N
ATOM	3418	CA	GLU	A	450	74.511	−1.628	36.982	1.00	53.36	C
ATOM	3420	CB	GLU	A	450	75.264	−2.664	37.793	1.00	54.22	C
ATOM	3423	CG	GLU	A	450	75.283	−2.370	39.276	1.00	61.11	C
ATOM	3426	CD	GLU	A	450	76.679	−2.074	39.841	1.00	69.67	C
ATOM	3427	OE1	GLU	A	450	77.608	−2.926	39.566	1.00	75.16	O
ATOM	3428	OE2	GLU	A	450	76.829	−1.029	40.578	1.00	71.51	O
ATOM	3429	C	GLU	A	450	74.794	−1.935	35.507	1.00	52.66	C
ATOM	3430	0	GLU	A	450	75.678	−1.297	34.888	1.00	53.17	O
ATOM	3432	N	LEU	A	451	74.062	−2.903	34.953	1.00	51.14	N
ATOM	3433	CA	LEU	A	451	74.248	−3.250	33.544	1.00	50.23	C
ATOM	3435	CB	LEU	A	451	73.541	−4.551	33.218	1.00	49.97	C
ATOM	3438	CG	LEU	A	451	74.094	−5.783	33.893	1.00	48.69	C
ATOM	3440	CD1	LEU	A	451	73.174	−6.955	33.683	1.00	48.35	C
ATOM	3444	CD2	LEU	A	451	75.438	−6.104	33.319	1.00	51.44	C
ATOM	3448	C	LEU	A	451	73.810	−2.131	32.595	1.00	49.31	C
ATOM	3449	O	LEU	A	451	74.529	−1.800	31.645	1.00	48.75	O
ATOM	3451	N	LEU	A	452	72.675	−1.522	32.884	1.00	48.98	N
ATOM	3452	CA	LEU	A	452	72.252	−0.304	32.141	1.00	49.73	C
ATOM	3454	CB	LEU	A	452	70.850	0.186	32.558	1.00	49.09	C
ATOM	3457	CG	LEU	A	452	69.688	−0.834	32.498	1.00	48.08	C
ATOM	3459	CD1	LEU	A	452	68.464	−0.367	33.250	1.00	47.95	C
ATOM	3463	CD2	LEU	A	452	69.302	−1.204	31.099	1.00	47.26	C
ATOM	3467	C	LEU	A	452	73.309	0.828	32.245	1.00	50.02	C
ATOM	3468	O	LEU	A	452	73.639	1.443	31.241	1.00	50.47	O
ATOM	3470	N	GLU	A	453	73.894	1.029	33.430	1.00	50.20	N
ATOM	3471	CA	GLU	A	453	74.995	2.000	33.617	1.00	50.60	C
ATOM	3473	CB	GLU	A	453	75.392	2.093	35.087	1.00	50.82	C
ATOM	3476	CG	GLU	A	453	76.242	3.328	35.399	1.00	51.95	C
ATOM	3479	CD	GLU	A	453	76.359	3.540	36.892	1.00	54.05	C
ATOM	3480	OE1	GLU	A	453	76.746	2.547	37.586	1.00	61.43	O
ATOM	3481	OE2	GLU	A	453	76.055	4.668	37.378	1.00	58.31	O
ATOM	3482	C	GLU	A	453	76.261	1.711	32.809	1.00	49.47	C
ATOM	3483	O	GLU	A	453	76.847	2.621	32.233	1.00	49.30	O
ATOM	3485	N	LYS	A	454	76.680	0.446	32.809	1.00	48.70	N
ATOM	3486	CA	LYS	A	454	77.765	−0.022	31.950	1.00	48.14	C
ATOM	3488	CB	LYS	A	454	78.368	−1.313	32.488	1.00	48.10	C
ATOM	3491	CG	LYS	A	454	78.985	−1.153	33.840	1.00	47.78	C
ATOM	3494	CD	LYS	A	454	80.230	−1.960	33.986	1.00	48.32	C
ATOM	3497	CE	LYS	A	454	80.950	−1.591	35.252	1.00	50.37	C
ATOM	3500	NZ	LYS	A	454	80.330	−2.232	36.415	1.00	51.50	N
ATOM	3504	C	LYS	A	454	77.338	−0.200	30.489	1.00	48.14	C
ATOM	3505	O	LYS	A	454	78.129	−0.660	29.674	1.00	47.25	O
ATOM	3507	N	ASP	A	455	76.091	0.149	30.159	1.00	48.43	N
ATOM	3508	CA	ASP	A	455	75.672	0.427	28.772	1.00	48.30	C
ATOM	3510	CB	ASP	A	455	76.795	1.242	28.023	1.00	48.40	C
ATOM	3513	CG	ASP	A	455	76.350	1.855	26.716	1.00	49.21	C
ATOM	3514	OD1	ASP	A	455	75.111	1.971	26.447	1.00	51.06	O
ATOM	3515	OD2	ASP	A	455	77.225	2.227	25.882	1.00	50.21	O
ATOM	3516	C	ASP	A	455	75.241	−0.873	28.061	1.00	47.27	C
ATOM	3517	O	ASP	A	455	75.527	−1.064	26.886	1.00	46.60	O
ATOM	3519	N	TYR	A	456	74.573	−1.759	28.810	1.00	46.29	N
ATOM	3520	CA	TYR	A	456	74.049	−3.012	28.282	1.00	45.50	C
ATOM	3522	CB	TYR	A	456	74.186	−4.178	29.272	1.00	45.82	C
ATOM	3525	CG	TYR	A	456	73.548	−5.448	28.732	1.00	45.17	C
ATOM	3526	CD1	TYR	A	456	74.217	−6.231	27.820	1.00	46.67	C
ATOM	3528	CE1	TYR	A	456	73.620	−7.382	27.300	1.00	48.52	C
ATOM	3530	CZ	TYR	A	456	72.330	−7.699	27.653	1.00	45.78	C
ATOM	3531	OH	TYR	A	456	71.788	−8.817	27.146	1.00	46.00	O
ATOM	3533	CE2	TYR	A	456	71.643	−6.914	28.521	1.00	46.03	C
ATOM	3535	CD2	TYR	A	456	72.246	−5.804	29.058	1.00	44.81	C
ATOM	3537	C	TYR	A	456	72.573	−2.822	27.999	1.00	45.07	C
ATOM	3538	O	TYR	A	456	71.860	−2.247	28.822	1.00	44.69	O
ATOM	3540	N	ARG	A	457	72.120	−3.335	26.852	1.00	44.67	N
ATOM	3541	CA	ARG	A	457	70.721	−3.301	26.445	1.00	44.17	C
ATOM	3543	CB	ARG	A	457	70.439	−2.169	25.473	1.00	43.75	C
ATOM	3546	CC	ARG	A	457	70.830	−0.789	25.989	1.00	41.99	C
ATOM	3549	CD	ARG	A	457	69.900	−0.329	27.047	1.00	40.73	C
ATOM	3552	NE	ARG	A	457	70.060	1.049	27.438	1.00	39.42	N
ATOM	3554	CZ	ARG	A	457	71.014	1.490	28.266	1.00	44.59	C
ATOM	3555	NH1	ARG	A	457	71.972	0.657	28.732	1.00	46.75	N
ATOM	3558	NH2	ARG	A	457	71.053	2.787	28.632	1.00	41.68	N
ATOM	3561	C	ARG	A	457	70.442	−4.614	25.776	1.00	45.28	C
ATOM	3562	O	ARG	A	457	71.338	−5.266	25.249	1.00	45.77	O
ATOM	3564	N	MET	A	458	69.174	−4.996	25.824	1.00	46.74	N
ATOM	3565	CA	MET	A	458	68.673	−6.223	25.276	1.00	47.04	C
ATOM	3567	CB	MET	A	458	67.153	−6.327	25.495	1.00	46.68	C
ATOM	3570	CG	MET	A	458	66.718	−6.782	26.905	1.00	46.91	C
ATOM	3573	SD	MET	A	458	64.868	−7.030	27.067	1.00	50.39	S
ATOM	3574	CE	MET	A	458	64.286	−5.185	27.361	1.00	50.07	C
ATOM	3578	C	MET	A	458	68.989	−6.216	23.793	1.00	47.60	C
ATOM	3579	O	MET	A	458	68.796	−5.235	23.082	1.00	48.87	O
ATOM	3581	N	GLU	A	459	69.485	−7.336	23.333	1.00	48.66	N
ATOM	3582	CA	GLU	A	459	69.792	−7.573	21.932	1.00	48.74	C
ATOM	3584	CB	GLU	A	459	70.420	−8.984	21.789	1.00	49.12	C
ATOM	3587	CG	GLU	A	459	69.491	−10.201	21.806	1.00	49.63	C
ATOM	3590	CD	GLU	A	459	68.971	−10.669	23.154	1.00	51.69	C
ATOM	3591	OE1	GLU	A	459	68.673	−9.785	23.984	1.00	51.46	O
ATOM	3592	OE2	GLU	A	459	68.825	−11.934	23.371	1.00	51.37	O
ATOM	3593	C	GLU	A	459	68.544	−7.483	21.100	1.00	48.46	C
ATOM	3594	O	GLU	A	459	67.471	−7.790	21.598	1.00	47.81	O
ATOM	3596	N	ARG	A	460	68.696	−7.061	19.850	1.00	48.70	N
ATOM	3597	CA	ARG	A	460	67.624	−7.146	18.850	1.00	49.66	C
ATOM	3599	CB	ARG	A	460	68.139	−6.651	17.514	1.00	48.54	C
ATOM	3602	CG	ARG	A	460	67.118	−6.584	16.439	1.00	51.59	C
ATOM	3605	CD	ARG	A	460	67.704	−6.694	15.030	1.00	54.46	C
ATOM	3608	NE	ARG	A	460	68.260	−5.409	14.647	1.00	59.82	N
ATOM	3610	CZ	ARG	A	460	67.883	−4.620	13.628	1.00	63.54	C
ATOM	3611	NH1	ARG	A	460	66.931	−4.991	12.762	1.00	66.66	N
ATOM	3614	NH2	ARG	A	460	68.518	−3.451	13.450	1.00	62.38	N
ATOM	3617	C	ARG	A	460	67.017	−8.594	18.728	1.00	49.50	C
ATOM	3618	O	ARG	A	460	67.725	−9.574	18.394	1.00	47.71	O
ATOM	3620	N	PRO	A	461	65.701	−8.719	18.985	1.00	50.24	N
ATOM	3621	CA	PRO	A	461	65.013	−10.050	18.867	1.00	50.10	C
ATOM	3623	CB	PRO	A	461	63.652	−9.804	19.541	1.00	50.43	C
ATOM	3626	CG	PRO	A	461	63.397	−8.320	19.350	1.00	50.15	C
ATOM	3629	CD	PRO	A	461	64.743	−7.641	19.341	1.00	49.66	C
ATOM	3632	C	PRO	A	461	64.785	−10.441	17.415	1.00	49.58	C
ATOM	3633	O	PRO	A	461	64.678	−9.554	16.571	1.00	49.88	O
ATOM	3634	N	GLU	A	462	64.672	−11.741	17.159	1.00	48.78	N
ATOM	3635	CA	GLU	A	462	64.534	−12.309	15.810	1.00	48.12	C
ATOM	3637	CB	GLU	A	462	64.095	−13.784	15.879	1.00	47.84	C
ATOM	3640	CG	GLU	A	462	63.910	−14.503	14.546	1.00	48.25	C
ATOM	3643	CD	GLU	A	462	65.141	−14.492	13.632	1.00	49.32	C
ATOM	3644	OE1	GLU	A	462	66.290	−14.437	14.105	1.00	49.65	O
ATOM	3645	OE2	GLU	A	462	64.970	−14.602	12.410	1.00	52.10	O
ATOM	3646	C	GLU	A	462	63.545	−11.573	14.961	1.00	47.92	C
ATOM	3647	O	GLU	A	462	62.391	−11.453	15.329	1.00	47.70	O
ATOM	3649	N	GLY	A	463	64.006	−11.055	13.826	1.00	48.83	N
ATOM	3650	CA	GLY	A	463	63.104	−10.503	12.810	1.00	49.16	C
ATOM	3653	C	GLY	A	463	62.495	−9.157	13.095	1.00	49.48	C
ATOM	3654	O	GLY	A	463	61.742	−8.664	12.283	1.00	50.32	O
ATOM	3656	N	CYS	A	464	62.818	−8.550	14.225	1.00	50.06	N
ATOM	3657	CA	CYS	A	464	62.429	−7.201	14.509	1.00	51.09	C
ATOM	3659	CB	CYS	A	464	63.089	−6.713	15.785	1.00	50.80	C
ATOM	3662	SG	CYS	A	464	62.533	−5.049	16.177	1.00	49.81	S
ATOM	3664	C	CYS	A	464	62.907	−6.325	13.382	1.00	52.38	C
ATOM	3665	O	CYS	A	464	64.061	−6.463	13.051	1.00	53.60	O
ATOM	3667	N	PRO	A	465	62.074	−5.486	12.753	1.00	53.51	N
ATOM	3668	CA	PRO	A	465	62.578	−4.554	11.754	1.00	55.11	C
ATOM	3670	CB	PRO	A	465	61.357	−3.692	11.419	1.00	54.64	C
ATOM	3673	CG	PRO	A	465	60.228	−4.579	11.639	1.00	53.39	C
ATOM	3676	CD	PRO	A	465	60.613	−5.394	12.852	1.00	53.16	C
ATOM	3679	C	PRO	A	465	63.729	−3.708	12.254	1.00	57.32	C
ATOM	3680	O	PRO	A	465	64.001	−3.683	13.431	1.00	58.76	O
ATOM	3681	N	GLU	A	466	64.413	−3.045	11.348	1.00	60.05	N
ATOM	3682	CA	GLU	A	466	65.592	−2.232	11.684	1.00	61.76	C
ATOM	3684	CB	GLU	A	466	66.490	−2.066	10.413	1.00	62.21	C
ATOM	3687	CG	GLU	A	466	67.817	−1.269	10.434	1.00	62.63	C
ATOM	3690	CD	GLU	A	466	68.532	−1.336	9.052	1.00	65.77	C
ATOM	3691	OE1	GLU	A	466	67.857	−1.040	8.002	1.00	70.31	O
ATOM	3692	OE2	GLU	A	466	69.752	−1.732	8.987	1.00	70.71	O
ATOM	3693	C	GLU	A	466	65.118	−0.946	12.321	1.00	61.51	C
ATOM	3694	O	GLU	A	466	65.655	−0.533	13.356	1.00	61.77	O
ATOM	3696	N	LYS	A	467	64.076	−0.355	11.757	1.00	61.30	N
ATOM	3697	CA	LYS	A	467	63.540	0.870	12.320	1.00	61.66	C
ATOM	3699	CB	LYS	A	467	62.741	1.665	11.281	1.00	61.79	C
ATOM	3702	CG	LYS	A	467	63.649	2.255	10.179	1.00	63.09	C
ATOM	3705	CD	LYS	A	467	62.947	3.410	9.409	1.00	63.74	C
ATOM	3708	CE	LYS	A	467	63.928	4.200	8.513	1.00	64.74	C
ATOM	3711	NZ	LYS	A	467	64.544	5.376	9.218	1.00	65.98	N
ATOM	3715	C	LYS	A	467	62.781	0.620	13.632	1.00	60.39	C
ATOM	3716	O	LYS	A	467	62.692	1.547	14.467	1.00	61.04	O
ATOM	3718	N	VAL	A	468	62.310	−0.614	13.869	1.00	58.38	N
ATOM	3719	CA	VAL	A	468	61.685	−0.915	15.169	1.00	57.02	C
ATOM	3721	CB	VAL	A	468	60.792	−2.157	15.123	1.00	56.81	C
ATOM	3723	CG1	VAL	A	468	60.201	−2.455	16.503	1.00	56.62	C
ATOM	3727	CG2	VAL	A	468	59.643	−1.958	14.170	1.00	56.56	C
ATOM	3731	C	VAL	A	468	62.787	−0.998	16.250	1.00	56.12	C
ATOM	3732	O	VAL	A	468	62.733	−0.259	17.251	1.00	55.88	O
ATOM	3734	N	TYR	A	469	63.798	−1.841	16.011	1.00	54.44	N
ATOM	3735	CA	TYR	A	469	64.979	−1.846	16.850	1.00	53.72	C
ATOM	3737	CB	TYR	A	469	66.038	−2.864	16.380	1.00	52.95	C
ATOM	3740	CG	TYR	A	469	67.069	−3.153	17.472	1.00	51.62	C
ATOM	3741	CD1	TYR	A	469	66.650	−3.712	18.677	1.00	51.92	C
ATOM	3743	CE1	TYR	A	469	67.533	−3.957	19.720	1.00	51.09	C
ATOM	3745	CZ	TYR	A	469	68.849	−3.666	19.575	1.00	50.41	C
ATOM	3746	OH	TYR	A	469	69.613	−3.933	20.699	1.00	50.90	O
ATOM	3748	CE2	TYR	A	469	69.316	−3.091	18.374	1.00	49.07	C
ATOM	3750	CD2	TYR	A	469	68.412	−2.834	17.334	1.00	47.04	C
ATOM	3752	C	TYR	A	469	65.633	−0.468	17.061	1.00	53.64	C
ATOM	3753	O	TYR	A	469	65.998	−0.172	18.174	1.00	53.66	O
ATOM	3755	N	GLU	A	470	65.753	0.373	16.031	1.00	54.40	N
ATOM	3756	CA	GLU	A	470	66.277	1.780	16.199	1.00	55.39	C
ATOM	3758	CB	GLU	A	470	66.272	2.617	14.893	1.00	55.85	C
ATOM	3761	CG	GLU	A	470	67.593	2.687	14.125	1.00	58.10	C
ATOM	3764	CD	GLU	A	470	67.420	3.018	12.619	1.00	58.70	C
ATOM	3765	OE1	GLU	A	470	66.577	3.927	12.274	1.00	58.60	O
ATOM	3766	OE2	GLU	A	470	68.148	2.351	11.796	1.00	59.32	O
ATOM	3767	C	GLU	A	470	65.473	2.570	17.217	1.00	55.05	C
ATOM	3768	O	GLU	A	470	66.053	3.318	18.005	1.00	54.93	O
ATOM	3770	N	LEU	A	471	64.142	2.429	17.156	1.00	54.69	N
ATOM	3771	CA	LEU	A	471	63.257	3.124	18.098	1.00	54.13	C
ATOM	3773	CB	LEU	A	471	61.781	3.052	17.700	1.00	54.07	C
ATOM	3776	CG	LEU	A	471	61.326	4.034	16.619	1.00	54.83	C
ATOM	3778	CD1	LEU	A	471	59.808	3.915	16.513	1.00	55.39	C
ATOM	3782	CD2	LEU	A	471	61.703	5.518	16.875	1.00	55.64	C
ATOM	3786	C	LEU	A	471	63.425	2.612	19.506	1.00	53.27	C
ATOM	3787	O	LEU	A	471	63.479	3.443	20.421	1.00	52.70	O
ATOM	3789	N	MET	A	472	63.519	1.279	19.662	1.00	52.60	N
ATOM	3790	CA	MET	A	472	63.811	0.657	20.954	1.00	52.58	C
ATOM	3792	CB	MET	A	472	64.038	−0.835	20.849	1.00	52.59	C
ATOM	3795	CG	MET	A	472	62.887	−1.649	20.491	1.00	52.73	C
ATOM	3798	SD	MET	A	472	63.389	−3.360	20.806	1.00	54.01	S
ATOM	3799	CE	MET	A	472	62.296	−4.161	19.742	1.00	53.53	C
ATOM	3803	C	MET	A	472	65.089	1.202	21.560	1.00	52.64	C
ATOM	3804	O	MET	A	472	65.135	1.516	22.752	1.00	52.03	O
ATOM	3806	N	ARG	A	473	66.131	1.294	20.747	1.00	52.93	N
ATOM	3807	CA	ARG	A	473	67.382	1.816	21.242	1.00	53.86	C
ATOM	3809	CB	ARG	A	473	68.525	1.437	20.307	1.00	54.51	C
ATOM	3812	CG	ARG	A	473	68.768	−0.075	20.223	1.00	55.83	C
ATOM	3815	CD	ARG	A	473	69.222	−0.757	21.543	1.00	60.55	C
ATOM	3818	NE	ARG	A	473	70.669	−1.090	21.660	1.00	63.39	N
ATOM	3820	CZ	ARG	A	473	71.625	−0.306	22.197	1.00	62.78	C
ATOM	3821	NH1	ARG	A	473	71.363	0.938	22.624	1.00	64.65	N
ATOM	3824	NH2	ARG	A	473	72.874	−0.766	22.269	1.00	61.38	N
ATOM	3827	C	ARG	A	473	67.378	3.307	21.584	1.00	54.09	C
ATOM	3828	O	ARG	A	473	68.053	3.711	22.522	1.00	54.89	O
ATOM	3830	N	ALA	A	474	66.598	4.121	20.876	1.00	54.43	N
ATOM	3831	CA	ALA	A	474	66.486	5.558	21.215	1.00	54.14	C
ATOM	3833	CB	ALA	A	474	65.930	6.381	20.037	1.00	53.93	C
ATOM	3837	C	ALA	A	474	65.608	5.702	22.459	1.00	54.26	C
ATOM	3838	O	ALA	A	474	65.831	6.604	23.308	1.00	54.45	O
ATOM	3840	N	CYS	A	475	64.615	4.814	22.568	1.00	52.81	N
ATOM	3841	CA	CYS	A	475	63.852	4.709	23.781	1.00	52.43	C
ATOM	3843	CB	CYS	A	475	62.721	3.684	23.629	1.00	53.07	C
ATOM	3846	SG	CYS	A	475	61.280	4.398	22.870	1.00	54.23	S
ATOM	3848	C	CYS	A	475	64.705	4.340	25.016	1.00	51.73	C
ATOM	3849	O	CYS	A	475	64.288	4.615	26.144	1.00	52.56	O
ATOM	3851	N	TRP	A	476	65.851	3.692	24.835	1.00	49.72	N
ATOM	3852	CA	TRP	A	476	66.674	3.329	25.965	1.00	48.31	C
ATOM	3854	CB	TRP	A	476	67.043	1.819	25.904	1.00	47.84	C
ATOM	3857	CG	TRP	A	476	65.866	0.886	25.808	1.00	45.66	C
ATOM	3858	CD1	TRP	A	476	64.620	1.116	26.282	1.00	45.95	C
ATOM	3860	NE1	TRP	A	476	63.814	0.034	26.041	1.00	46.25	N
ATOM	3862	CE2	TRP	A	476	64.538	−0.930	25.406	1.00	44.25	C
ATOM	3863	CD2	TRP	A	476	65.846	−0.416	25.236	1.00	42.39	C
ATOM	3864	CE3	TRP	A	476	66.796	−1.208	24.586	1.00	44.51	C
ATOM	3866	CZ3	TRP	A	476	66.412	−2.489	24.128	1.00	46.64	C
ATOM	3868	CH2	TRP	A	476	65.080	−2.974	24.318	1.00	46.33	C
ATOM	3870	CZ2	TRP	A	476	64.139	−2.204	24.947	1.00	45.55	C
ATOM	3872	C	TRP	A	476	67.896	4.226	26.140	1.00	48.26	C
ATOM	3873	O	TRP	A	476	68.862	3.814	26.736	1.00	47.55	O
ATOM	3875	N	GLN	A	477	67.852	5.466	25.681	1.00	48.88	N
ATOM	3876	CA	GLN	A	477	68.919	6.393	26.022	1.00	50.02	C
ATOM	3878	CB	GLN	A	477	68.749	7.740	25.320	1.00	50.10	C
ATOM	3881	CG	GLN	A	477	68.906	7.676	23.809	1.00	51.99	C
ATOM	3884	CD	GLN	A	477	70.272	7.187	23.334	1.00	53.01	C
ATOM	3885	OE1	GLN	A	477	71.301	7.563	23.864	1.00	54.29	O
ATOM	3886	NE2	GLN	A	477	70.264	6.348	22.325	1.00	54.64	N
ATOM	3889	C	GLN	A	477	68.982	6.608	27.560	1.00	50.32	C
ATOM	3890	O	GLN	A	477	67.965	6.807	28.212	1.00	49.81	O
ATOM	3892	N	TRP	A	478	70.191	6.483	28.115	1.00	50.78	N
ATOM	3893	CA	TRP	A	478	70.470	6.747	29.519	1.00	50.64	C
ATOM	3895	CB	TRP	A	478	71.995	6.699	29.789	1.00	49.49	C
ATOM	3898	CG	TRP	A	478	72.350	6.853	31.240	1.00	49.47	C
ATOM	3899	CD1	TRP	A	478	72.749	7.999	31.875	1.00	47.77	C
ATOM	3901	NE1	TRP	A	478	72.938	7.747	33.212	1.00	48.01	N
ATOM	3903	CE2	TRP	A	478	72.645	6.435	33.477	1.00	46.76	C
ATOM	3904	CD2	TRP	A	478	72.277	5.834	32.259	1.00	48.94	C
ATOM	3905	CE3	TRP	A	478	71.951	4.457	32.257	1.00	48.50	C
ATOM	3907	CZ3	TRP	A	478	72.005	3.752	33.427	1.00	47.37	C
ATOM	3909	CH2	TRP	A	478	72.399	4.374	34.610	1.00	48.27	C
ATOM	3911	CZ2	TRP	A	478	72.709	5.723	34.658	1.00	47.03	C
ATOM	3913	C	TRP	A	478	69.891	8.099	29.905	1.00	52.22	C
ATOM	3914	O	TRP	A	478	69.149	8.200	30.877	1.00	53.74	O
ATOM	3916	N	ASN	A	479	70.185	9.116	29.113	1.00	53.24	N
ATOM	3917	CA	ASN	A	479	69.860	10.481	29.463	1.00	54.64	C
ATOM	3919	CB	ASN	A	479	71.044	11.321	28.992	1.00	55.18	C
ATOM	3922	CG	ASN	A	479	70.877	12.791	29.199	1.00	58.30	C
ATOM	3923	OD1	ASN	A	479	69.817	13.342	29.634	1.00	63.42	O
ATOM	3924	ND2	ASN	A	479	71.936	13.482	28.835	1.00	62.13	N
ATOM	3927	C	ASN	A	479	68.479	10.850	28.815	1.00	54.77	C
ATOM	3928	O	ASN	A	479	68.384	10.918	27.582	1.00	54.48	O
ATOM	3930	N	PRO	A	480	67.424	11.081	29.623	1.00	54.97	N
ATOM	3931	CA	PRO	A	480	66.022	11.238	29.086	1.00	55.15	C
ATOM	3933	CB	PRO	A	480	65.139	11.515	30.323	1.00	54.60	C
ATOM	3936	CG	PRO	A	480	66.028	11.573	31.486	1.00	54.84	C
ATOM	3939	CD	PRO	A	480	67.456	11.187	31.086	1.00	54.86	C
ATOM	3942	C	PRO	A	480	65.790	12.298	28.022	1.00	55.19	C
ATOM	3943	O	PRO	A	480	64.904	12.137	27.195	1.00	55.66	O
ATOM	3944	N	SER	A	481	66.575	13.358	28.011	1.00	55.30	N
ATOM	3945	CA	SER	A	481	66.457	14.338	26.919	1.00	55.50	C
ATOM	3947	CB	SER	A	481	67.364	15.559	27.154	1.00	55.82	C
ATOM	3950	OG	SER	A	481	68.503	15.207	27.961	1.00	58.24	O
ATOM	3952	C	SER	A	481	66.741	13.626	25.586	1.00	54.92	C
ATOM	3953	O	SER	A	481	66.020	13.823	24.623	1.00	54.70	O
ATOM	3955	N	ASP	A	482	67.719	12.717	25.587	1.00	54.83	N
ATOM	3956	CA	ASP	A	482	68.109	11.961	24.376	1.00	54.45	C
ATOM	3958	CB	ASP	A	482	69.522	11.319	24.542	1.00	54.20	C
ATOM	3961	CG	ASP	A	482	70.635	12.372	24.904	1.00	54.75	C
ATOM	3962	OD1	ASP	A	482	70.452	13.571	24.551	1.00	57.92	O
ATOM	3963	OD2	ASP	A	482	71.704	12.132	25.541	1.00	51.96	O
ATOM	3964	C	ASP	A	482	67.031	10.981	23.872	1.00	53.70	C
ATOM	3965	O	ASP	A	482	67.035	10.625	22.736	1.00	54.26	O
ATOM	3967	N	ARG	A	483	66.082	10.592	24.696	1.00	53.87	N
ATOM	3968	CA	ARG	A	483	64.925	9.779	24.241	1.00	54.11	C
ATOM	3970	CB	ARG	A	483	64.112	9.271	25.458	1.00	53.35	C
ATOM	3973	CG	ARG	A	483	64.577	7.925	25.921	1.00	53.98	C
ATOM	3976	CD	ARG	A	483	64.210	7.575	27.353	1.00	54.09	C
ATOM	3979	NE	ARG	A	483	65.292	7.759	28.303	1.00	52.99	N
ATOM	3981	CZ	ARG	A	483	65.168	7.624	29.622	1.00	51.34	C
ATOM	3982	NH1	ARG	A	483	63.992	7.306	30.185	1.00	50.07	N
ATOM	3985	NH2	ARG	A	483	66.227	7.853	30.386	1.00	49.97	N
ATOM	3988	C	ARG	A	483	63.993	10.495	23.253	1.00	53.94	C
ATOM	3989	O	ARG	A	483	63.841	11.671	23.399	1.00	55.23	O
ATOM	3991	N	PRO	A	484	63.335	9.802	22.308	1.00	54.47	N
ATOM	3992	CA	PRO	A	484	62.263	10.417	21.500	1.00	54.61	C
ATOM	3994	CB	PRO	A	484	61.876	9.309	20.488	1.00	54.75	C
ATOM	3997	CG	PRO	A	484	62.285	7.993	21.153	1.00	55.15	C
ATOM	4000	CD	PRO	A	484	63.515	8.369	21.947	1.00	55.04	C
ATOM	4003	C	PRO	A	484	61.020	10.794	22.326	1.00	55.19	C
ATOM	4004	O	PRO	A	484	60.988	10.609	23.549	1.00	55.44	O
ATOM	4005	N	SER	A	485	60.020	11.341	21.638	1.00	55.35	N
ATOM	4006	CA	SER	A	485	58.719	11.660	22.207	1.00	55.13	C
ATOM	4008	CB	SER	A	485	58.364	13.078	21.815	1.00	55.10	C
ATOM	4011	OG	SER	A	485	57.848	13.045	20.505	1.00	55.57	O
ATOM	4013	C	SER	A	485	57.676	10.711	21.624	1.00	54.79	C
ATOM	4014	O	SER	A	485	57.907	10.093	20.584	1.00	53.34	O
ATOM	4016	N	PHE	A	486	56.514	10.646	22.265	1.00	54.96	N
ATOM	4017	CA	PHE	A	486	55.416	9.819	21.747	1.00	55.83	C
ATOM	4019	CB	PHE	A	486	54.340	9.602	22.801	1.00	55.92	C
ATOM	4022	CG	PHE	A	486	54.715	8.575	23.817	1.00	56.95	C
ATOM	4023	CD1	PHE	A	486	54.854	7.245	23.441	1.00	55.57	C
ATOM	4025	CE1	PHE	A	486	55.210	6.280	24.392	1.00	56.99	C
ATOM	4027	CZ	PHE	A	486	55.426	6.639	25.725	1.00	56.16	C
ATOM	4029	CE2	PHE	A	486	55.277	7.963	26.111	1.00	56.57	C
ATOM	4031	CD2	PHE	A	486	54.916	8.929	25.168	1.00	57.32	C
ATOM	4033	C	PHE	A	486	54.793	10.300	20.409	1.00	56.20	C
ATOM	4034	O	PHE	A	486	54.397	9.437	19.565	1.00	55.89	O
ATOM	4036	N	ALA	A	487	54.718	11.635	20.227	1.00	55.77	N
ATOM	4037	CA	ALA	A	487	54.428	12.232	18.914	1.00	55.99	C
ATOM	4039	CB	ALA	A	487	54.392	13.755	19.001	1.00	55.56	C
ATOM	4043	C	ALA	A	487	55.441	11.749	17.837	1.00	56.19	C
ATOM	4044	O	ALA	A	487	55.019	11.195	16.816	1.00	55.87	O
ATOM	4046	N	GLU	A	488	56.751	11.888	18.112	1.00	56.63	N
ATOM	4047	CA	GLU	A	488	57.824	11.403	17.215	1.00	57.49	C
ATOM	4049	CB	GLU	A	488	59.221	11.616	17.817	1.00	57.41	C
ATOM	4052	CG	GLU	A	488	59.751	13.040	17.893	1.00	59.42	C
ATOM	4055	CD	GLU	A	488	61.073	13.151	18.673	1.00	60.53	C
ATOM	4056	OE1	GLU	A	488	61.989	12.316	18.476	1.00	66.04	O
ATOM	4057	OE2	GLU	A	488	61.229	14.087	19.489	1.00	65.98	O
ATOM	4058	C	GLU	A	488	57.679	9.912	16.870	1.00	57.66	C
ATOM	4059	O	GLU	A	488	57.728	9.570	15.694	1.00	58.17	O
ATOM	4061	N	ILE	A	489	57.506	9.063	17.902	1.00	57.93	N
ATOM	4062	CA	ILE	A	489	57.424	7.593	17.797	1.00	57.80	C
ATOM	4064	CB	ILE	A	489	57.316	6.917	19.216	1.00	57.97	C
ATOM	4066	CG1	ILE	A	489	58.635	7.023	19.992	1.00	57.93	C
ATOM	4069	CD1	ILE	A	489	58.506	6.904	21.514	1.00	57.02	C
ATOM	4073	CG2	ILE	A	489	56.900	5.422	19.139	1.00	57.66	C
ATOM	4077	C	ILE	A	489	56.219	7.191	16.997	1.00	59.21	C
ATOM	4078	O	ILE	A	489	56.345	6.328	16.117	1.00	59.18	O
ATOM	4080	N	HIS	A	490	55.048	7.766	17.333	1.00	60.68	N
ATOM	4081	CA	HIS	A	490	53.781	7.429	16.642	1.00	61.52	C
ATOM	4083	CB	HIS	A	490	52.585	8.197	17.204	1.00	61.77	C
ATOM	4086	CG	HIS	A	490	51.278	7.876	16.521	1.00	61.77	C
ATOM	4087	ND1	HIS	A	490	50.864	6.581	16.273	1.00	62.15	N
ATOM	4089	CE1	HIS	A	490	49.683	6.601	15.685	1.00	60.38	C
ATOM	4091	NE2	HIS	A	490	49.315	7.857	15.545	1.00	60.73	N
ATOM	4093	CD2	HIS	A	490	50.294	8.677	16.052	1.00	60.01	C
ATOM	4095	C	HIS	A	490	53.876	7.716	15.150	1.00	62.34	C
ATOM	4096	O	HIS	A	490	53.542	6.847	14.332	1.00	61.47	O
ATOM	4098	N	GLN	A	491	54.343	8.936	14.842	1.00	63.75	N
ATOM	4099	CA	GLN	A	491	54.633	9.393	13.468	1.00	64.86	C
ATOM	4101	CB	GLN	A	491	55.398	10.727	13.467	1.00	64.77	C
ATOM	4104	CG	GLN	A	491	55.596	11.400	12.095	1.00	64.80	C
ATOM	4107	CD	GLN	A	491	54.293	11.834	11.434	1.00	65.11	C
ATOM	4108	OE1	GLN	A	491	53.898	11.287	10.398	1.00	64.93	O
ATOM	4109	NE2	GLN	A	491	53.624	12.805	12.037	1.00	63.54	N
ATOM	4112	C	GLN	A	491	55.445	8.383	12.696	1.00	66.25	C
ATOM	4113	O	GLN	A	491	55.044	8.004	11.603	1.00	66.66	O
ATOM	4115	N	ALA	A	492	56.575	7.963	13.280	1.00	67.77	N
ATOM	4116	CA	ALA	A	492	57.439	6.919	12.708	1.00	68.89	C
ATOM	4118	CB	ALA	A	492	58.673	6.692	13.561	1.00	68.89	C
ATOM	4122	C	ALA	A	492	56.705	5.603	12.509	1.00	69.86	C
ATOM	4123	O	ALA	A	492	56.892	4.962	11.477	1.00	70.02	O
ATOM	4125	N	PHE	A	493	55.871	5.223	13.479	1.00	70.90	N
ATOM	4126	CA	PHE	A	493	55.052	4.017	13.345	1.00	72.05	C
ATOM	4128	CB	PHE	A	493	54.393	3.598	14.664	1.00	71.47	C
ATOM	4131	CG	PHE	A	493	55.226	2.669	15.461	1.00	70.61	C
ATOM	4132	CD1	PHE	A	493	55.283	1.326	15.114	1.00	69.27	C
ATOM	4134	CE1	PHE	A	493	56.062	0.460	15.824	1.00	69.40	C
ATOM	4136	CZ	PHE	A	493	56.816	0.922	16.911	1.00	69.74	C
ATOM	4138	CE2	PHE	A	493	56.771	2.265	17.268	1.00	69.29	C
ATOM	4140	CD2	PHE	A	493	55.984	3.131	16.539	1.00	69.63	C
ATOM	4142	C	PHE	A	493	53.993	4.156	12.281	1.00	72.91	C
ATOM	4143	O	PHE	A	493	53.815	3.215	11.533	1.00	72.99	O
ATOM	4145	N	GLU	A	494	53.293	5.301	12.233	1.00	74.32	N
ATOM	4146	CA	GLU	A	494	52.277	5.592	11.184	1.00	75.23	C
ATOM	4148	CB	GLU	A	494	51.758	7.046	11.234	1.00	75.46	C
ATOM	4151	CG	GLU	A	494	50.381	7.244	11.855	1.00	75.68	C
ATOM	4154	CD	GLU	A	494	49.858	8.655	11.601	1.00	76.06	C
ATOM	4155	OE1	GLU	A	494	50.272	9.603	12.328	1.00	75.88	O
ATOM	4156	OE2	GLU	A	494	49.044	8.822	10.652	1.00	77.47	O
ATOM	4157	C	GLU	A	494	52.866	5.328	9.809	1.00	76.90	C
ATOM	4158	O	GLU	A	494	52.349	4.485	9.082	1.00	76.96	O
ATOM	4160	N	THR	A	495	53.968	6.033	9.508	1.00	78.73	N
ATOM	4161	CA	THR	A	495	54.827	5.807	8.323	1.00	80.18	C
ATOM	4163	CB	THR	A	495	56.141	6.658	8.435	1.00	79.88	C
ATOM	4165	OG1	THR	A	495	55.847	8.024	8.122	1.00	79.58	O
ATOM	4167	CG2	THR	A	495	57.216	6.267	7.395	1.00	79.47	C
ATOM	4171	C	THR	A	495	55.134	4.319	8.081	1.00	80.99	C
ATOM	4172	O	THR	A	495	54.543	3.735	7.182	1.00	80.95	O
ATOM	4174	N	MET	A	496	56.009	3.722	8.904	1.00	82.49	N
ATOM	4175	CA	MET	A	496	56.347	2.263	8.864	1.00	83.49	C
ATOM	4177	CB	MET	A	496	57.035	1.823	10.172	1.00	83.57	C
ATOM	4180	CG	MET	A	496	58.482	2.231	10.294	1.00	83.65	C
ATOM	4183	SD	MET	A	496	59.290	1.292	11.589	1.00	84.99	S
ATOM	4184	CE	MET	A	496	58.899	2.235	13.040	1.00	86.07	C
ATOM	4188	C	MET	A	496	55.165	1.310	8.645	1.00	84.97	C
ATOM	4189	O	MET	A	496	55.289	0.301	7.927	1.00	85.05	O
ATOM	4191	N	PHE	A	497	54.039	1.640	9.284	1.00	86.49	N
ATOM	4192	CA	PHE	A	497	52.826	0.834	9.204	1.00	87.64	C
ATOM	4194	CB	PHE	A	497	51.818	1.203	10.304	1.00	87.70	C
ATOM	4197	CG	PHE	A	497	50.590	0.352	10.286	1.00	87.51	C
ATOM	4198	CD1	PHE	A	497	50.704	−1.052	10.370	1.00	87.55	C
ATOM	4200	CE1	PHE	A	497	49.574	−1.878	10.322	1.00	87.67	C
ATOM	4202	CZ	PHE	A	497	48.303	−1.297	10.189	1.00	88.27	C
ATOM	4204	CE2	PHE	A	497	48.180	0.121	10.097	1.00	88.29	C
ATOM	4206	CD2	PHE	A	497	49.328	0.927	10.138	1.00	87.42	C
ATOM	4208	C	PHE	A	497	52.143	0.876	7.832	1.00	88.50	C
ATOM	4209	O	PHE	A	497	51.702	−0.175	7.344	1.00	89.13	O
ATOM	4211	N	GLN	A	498	52.045	2.055	7.217	1.00	89.15	N
ATOM	4212	CA	GLN	A	498	51.504	2.138	5.843	1.00	89.92	C
ATOM	4214	CB	GLN	A	498	51.051	3.566	5.475	1.00	89.97	C
ATOM	4217	CG	GLN	A	498	49.986	4.196	6.436	1.00	90.20	C
ATOM	4220	CD	GLN	A	498	48.601	3.502	6.466	1.00	89.97	C
ATOM	4221	OE1	GLN	A	498	48.414	2.380	5.983	1.00	89.61	O
ATOM	4222	NE2	GLN	A	498	47.632	4.196	7.050	1.00	89.92	N
ATOM	4225	C	GLN	A	498	52.416	1.531	4.746	1.00	90.23	C
ATOM	4226	O	GLN	A	498	51.903	1.173	3.688	1.00	90.77	O
ATOM	4228	N	OLU	A	499	53.724	1.386	5.005	1.00	90.48	N
ATOM	4229	CA	GLU	A	499	54.694	0.785	4.059	1.00	90.46	C
ATOM	4231	CB	GLU	A	499	56.057	1.479	4.186	1.00	90.46	C
ATOM	4234	CG	GLU	A	499	56.010	2.982	3.896	1.00	90.15	C
ATOM	4237	CD	GLU	A	499	57.265	3.740	4.314	1.00	89.99	C
ATOM	4238	OE1	GLU	A	499	58.032	3.282	5.192	1.00	89.84	O
ATOM	4239	OE2	GLU	A	499	57.479	4.831	3.765	1.00	88.66	O
ATOM	4240	C	GLU	A	499	54.805	−0.719	4.336	1.00	90.94	C
ATOM	4241	O	GLU	A	499	55.865	−1.225	4.702	1.00	91.32	O
ATOM	4243	N	SER	A	500	53.687	−1.420	4.153	1.00	91.34	N
ATOM	4244	CA	SER	A	500	53.482	−2.774	4.699	1.00	91.48	C
ATOM	4246	CB	SER	A	500	53.236	−2.676	6.225	1.00	91.48	C
ATOM	4249	OG	SER	A	500	53.852	−3.733	6.937	1.00	91.48	O
ATOM	4251	C	SER	A	500	52.331	−3.501	3.947	1.00	91.62	C
ATOM	4252	O	SER	A	500	51.229	−3.831	4.416	1.00	91.62	O
ATOM	4254	OXT	SER	A	500	52.495	−3.764	2.756	1.00	91.74	O
ATOM	4255	N	ASP	B	233	29.222	7.771	67.736	1.00	71.87	N
ATOM	4256	CA	ASP	B	233	28.675	8.257	66.421	1.00	71.71	C
ATOM	4258	CB	ASP	B	233	28.316	9.765	66.513	1.00	71.81	C
ATOM	4261	CG	ASP	B	233	29.506	10.691	66.271	1.00	71.64	C
ATOM	4262	OD1	ASP	B	233	29.858	10.923	65.103	1.00	70.89	O
ATOM	4263	OD2	ASP	B	233	30.123	11.274	67.177	1.00	73.18	O
ATOM	4264	C	ASP	B	233	29.599	7.910	65.212	1.00	71.33	C
ATOM	4265	O	ASP	B	233	30.555	7.140	65.357	1.00	70.95	O
ATOM	4269	N	LYS	B	234	29.252	8.464	64.046	1.00	70.98	N
ATOM	4270	CA	LYS	B	234	29.985	8.337	62.771	1.00	71.17	C
ATOM	4272	CB	LYS	B	234	29.605	9.502	61.831	1.00	71.49	C
ATOM	4275	CG	LYS	B	234	28.140	9.548	61.391	1.00	72.11	C
ATOM	4278	CD	LYS	B	234	27.460	10.906	61.643	1.00	72.06	C
ATOM	4281	CE	LYS	B	234	25.956	10.763	61.376	1.00	72.83	C
ATOM	4284	NZ	LYS	B	234	25.242	12.059	61.296	1.00	73.36	N
ATOM	4288	C	LYS	B	234	31.498	8.354	62.918	1.00	71.01	C
ATOM	4289	O	LYS	B	234	32.181	7.420	62.527	1.00	71.04	O
ATOM	4291	N	TRP	B	235	31.992	9.420	63.525	1.00	70.76	N
ATOM	4292	CA	TRP	B	235	33.419	9.706	63.599	1.00	70.82	C
ATOM	4294	CB	TRP	B	235	33.635	11.196	63.929	1.00	70.12	C
ATOM	4297	CG	TRP	B	235	33.097	12.052	62.851	1.00	69.28	C
ATOM	4298	CD1	TRP	B	235	31.938	12.758	62.863	1.00	68.49	C
ATOM	4300	NE1	TRP	B	235	31.756	13.392	61.656	1.00	68.33	N
ATOM	4302	CE2	TRP	B	235	32.801	13.080	60.827	1.00	68.11	C
ATOM	4303	CD2	TRP	B	235	33.661	12.217	61.550	1.00	69.02	C
ATOM	4304	CE3	TRP	B	235	34.832	11.743	60.922	1.00	68.43	C
ATOM	4306	CZ3	TRP	B	235	35.101	12.140	59.613	1.00	68.67	C
ATOM	4308	CH2	TRP	B	235	34.218	13.006	58.914	1.00	68.53	C
ATOM	4310	CZ2	TRP	B	235	33.070	13.483	59.504	1.00	68.14	C
ATOM	4312	C	TRP	B	235	34.155	8.840	64.604	1.00	71.63	C
ATOM	4313	O	TRP	B	235	35.295	8.455	64.374	1.00	72.01	O
ATOM	4315	N	GLU	B	236	33.495	8.523	65.711	1.00	72.93	N
ATOM	4316	CA	GLU	B	236	34.128	7.832	66.841	1.00	73.75	C
ATOM	4318	CB	GLU	B	236	33.185	7.742	68.038	1.00	73.42	C
ATOM	4321	CG	GLU	B	236	32.846	9.116	68.630	1.00	72.96	C
ATOM	4324	CD	GLU	B	236	33.809	9.616	69.692	1.00	71.46	C
ATOM	4325	OE1	GLU	B	236	34.782	8.902	70.093	1.00	72.48	O
ATOM	4326	OE2	GLU	B	236	33.567	10.749	70.139	1.00	67.53	O
ATOM	4327	C	GLU	B	236	34.569	6.447	66.454	1.00	75.16	C
ATOM	4328	O	GLU	B	236	33.948	5.801	65.594	1.00	75.36	O
ATOM	4330	N	MET	B	237	35.651	6.005	67.092	1.00	76.54	N
ATOM	4331	CA	MET	B	237	36.283	4.738	66.758	1.00	77.67	C
ATOM	4333	CB	MET	B	237	37.071	4.936	65.480	1.00	77.70	C
ATOM	4336	CG	MET	B	237	37.915	6.168	65.480	1.00	78.27	C
ATOM	4339	SD	MET	B	237	39.363	5.931	64.441	1.00	81.61	S
ATOM	4340	CE	MET	B	237	40.430	4.806	65.532	1.00	81.78	C
ATOM	4344	C	MET	B	237	37.207	4.205	67.848	1.00	77.29	C
ATOM	4345	O	MET	B	237	37.685	4.969	68.689	1.00	77.20	O
ATOM	4347	N	GLU	B	238	37.500	2.904	67.780	1.00	77.21	N
ATOM	4348	CA	GLU	B	238	38.237	2.233	68.843	1.00	77.20	C
ATOM	4350	CB	GLU	B	238	37.967	0.721	68.835	1.00	76.95	C
ATOM	4353	CG	GLU	B	238	38.670	−0.097	69.930	1.00	76.85	C
ATOM	4356	CD	GLU	B	238	38.468	0.427	71.356	1.00	75.50	C
ATOM	4357	OE1	GLU	B	238	37.395	0.996	71.667	1.00	73.17	O
ATOM	4358	OE2	GLU	B	238	39.397	0.264	72.175	1.00	74.62	O
ATOM	4359	C	GLU	B	238	39.743	2.551	68.819	1.00	77.16	C
ATOM	4360	O	GLU	B	238	40.409	2.421	67.799	1.00	76.61	O
ATOM	4362	N	ARG	B	239	40.225	2.979	69.983	1.00	77.90	N
ATOM	4363	CA	ARG	B	239	41.631	3.341	70.292	1.00	78.53	C
ATOM	4365	CB	ARG	B	239	41.656	3.722	71.780	1.00	78.71	C
ATOM	4368	CG	ARG	B	239	42.986	4.044	72.465	1.00	79.31	C
ATOM	4371	CD	ARG	B	239	42.787	4.405	73.935	1.00	79.93	C
ATOM	4374	NE	ARG	B	239	41.766	5.467	74.096	1.00	81.57	N
ATOM	4376	CZ	ARG	B	239	41.979	6.735	74.493	1.00	82.84	C
ATOM	4377	NH1	ARG	B	239	43.206	7.169	74.840	1.00	83.83	N
ATOM	4380	NH2	ARG	B	239	40.941	7.572	74.584	1.00	80.98	N
ATOM	4383	C	ARG	B	239	42.687	2.256	70.029	1.00	78.60	C
ATOM	4384	O	ARG	B	239	43.789	2.557	69.564	1.00	78.18	O
ATOM	4386	N	THR	B	240	42.347	1.020	70.420	1.00	79.26	N
ATOM	4387	CA	THR	B	240	43.070	−0.224	70.063	1.00	79.27	C
ATOM	4389	CB	THR	B	240	42.139	−1.433	70.234	1.00	79.22	C
ATOM	4391	OG1	THR	B	240	41.579	−1.398	71.544	1.00	79.76	O
ATOM	4393	CG2	THR	B	240	42.890	−2.790	70.153	1.00	79.35	C
ATOM	4397	C	THR	B	240	43.550	−0.215	68.627	1.00	79.68	C
ATOM	4398	O	THR	B	240	44.727	−0.444	68.381	1.00	79.72	O
ATOM	4400	N	ASP	B	241	42.632	0.108	67.706	1.00	80.02	N
ATOM	4401	CA	ASP	B	241	42.865	0.040	66.262	1.00	80.43	C
ATOM	4403	CB	ASP	B	241	41.699	0.654	65.456	1.00	80.82	C
ATOM	4406	CG	ASP	B	241	40.405	−0.193	65.517	1.00	81.92	C
ATOM	4407	OD1	ASP	B	241	40.123	−0.797	66.580	1.00	82.58	O
ATOM	4408	OD2	ASP	B	241	39.610	−0.309	64.544	1.00	82.91	O
ATOM	4409	C	ASP	B	241	44.183	0.666	65.818	1.00	80.54	C
ATOM	4410	O	ASP	B	241	44.813	0.135	64.908	1.00	80.61	O
ATOM	4412	N	ILE	B	242	44.607	1.741	66.496	1.00	80.62	N
ATOM	4413	CA	ILE	B	242	45.839	2.491	66.170	1.00	80.66	C
ATOM	4415	CB	ILE	B	242	45.614	4.029	66.403	1.00	80.79	C
ATOM	4417	CG1	ILE	B	242	44.297	4.533	65.785	1.00	81.46	C
ATOM	4420	CD1	ILE	B	242	43.630	5.535	66.665	1.00	81.89	C
ATOM	4424	CG2	ILE	B	242	46.771	4.852	65.839	1.00	80.63	C
ATOM	4428	C	ILE	B	242	47.105	2.038	66.972	1.00	80.54	C
ATOM	4429	O	ILE	B	242	47.154	2.213	68.202	1.00	80.22	O
ATOM	4431	N	THR	B	243	48.106	1.474	66.272	1.00	80.39	N
ATOM	4432	CA	THR	B	243	49.513	1.429	66.754	1.00	80.36	C
ATOM	4434	CB	THR	B	243	50.408	0.469	65.903	1.00	80.46	C
ATOM	4436	OG1	THR	B	243	49.920	−0.884	65.937	1.00	79.79	O
ATOM	4438	CG2	THR	B	243	51.839	0.364	66.481	1.00	80.52	C
ATOM	4442	C	THR	B	243	50.081	2.845	66.610	1.00	80.50	C
ATOM	4443	O	THR	B	243	49.795	3.500	65.617	1.00	80.99	O
ATOM	4445	N	MET	B	244	50.900	3.291	67.570	1.00	80.35	N
ATOM	4446	CA	MET	B	244	51.532	4.632	67.560	1.00	80.01	C
ATOM	4448	CB	MET	B	244	51.321	5.307	68.899	1.00	79.71	C
ATOM	4451	CG	MET	B	244	49.874	5.491	69.311	1.00	80.04	C
ATOM	4454	SD	MET	B	244	49.308	7.231	69.362	1.00	82.18	S
ATOM	4455	CE	MET	B	244	50.604	8.042	70.563	1.00	81.97	C
ATOM	4459	C	MET	B	244	53.047	4.515	67.305	1.00	79.70	C
ATOM	4460	O	MET	B	244	53.739	3.740	67.994	1.00	79.69	O
ATOM	4462	N	LYS	B	245	53.557	5.298	66.349	1.00	79.19	N
ATOM	4463	CA	LYS	B	245	54.965	5.245	65.924	1.00	78.77	C
ATOM	4465	CB	LYS	B	245	55.083	5.254	64.393	1.00	78.72	C
ATOM	4468	CG	LYS	B	245	54.220	4.205	63.668	1.00	78.36	C
ATOM	4471	CD	LYS	B	245	54.461	4.240	62.143	1.00	78.35	C
ATOM	4474	CE	LYS	B	245	55.620	3.359	61.703	1.00	78.65	C
ATOM	4477	NZ	LYS	B	245	55.778	3.231	60.224	1.00	78.02	N
ATOM	4481	C	LYS	B	245	55.818	6.342	66.598	1.00	78.54	C
ATOM	4482	O	LYS	B	245	56.403	6.072	67.634	1.00	79.30	O
ATOM	4484	N	HIS	B	246	55.884	7.557	66.058	1.00	78.04	N
ATOM	4485	CA	HIS	B	246	56.888	8.554	66.501	1.00	77.74	C
ATOM	4487	CB	HIS	B	246	58.214	8.416	65.721	1.00	78.75	C
ATOM	4490	CG	HIS	B	246	58.116	8.657	64.229	1.00	82.12	C
ATOM	4491	ND1 HIS	B	246	57.981	7.631	63.307	1.00	84.97	N
ATOM	4493	CE1	HIS	B	246	57.977	8.132	62.082	1.00	84.48	C
ATOM	4495	NE2	HIS	B	246	58.111	9.446	62.170	1.00	85.17	N
ATOM	4497	CD2	HIS	B	246	58.214	9.799	63.498	1.00	84.33	C
ATOM	4499	C	HIS	B	246	56.389	9.971	66.404	1.00	76.54	C
ATOM	4500	O	HIS	B	246	55.593	10.260	65.523	1.00	75.60	O
ATOM	4502	N	LYS	B	247	56.879	10.841	67.300	1.00	75.69	N
ATOM	4503	CA	LYS	B	247	56.505	12.289	67.328	1.00	75.38	C
ATOM	4505	CB	LYS	B	247	57.204	13.028	68.483	1.00	75.17	C
ATOM	4508	CG	LYS	B	247	56.697	14.423	68.746	1.00	74.61	C
ATOM	4511	CD	LYS	B	247	56.926	14.830	70.189	1.00	74.47	C
ATOM	4514	CE	LYS	B	247	56.490	16.264	70.447	1.00	73.93	C
ATOM	4517	NZ	LYS	B	247	56.085	16.466	71.853	1.00	73.65	N
ATOM	4521	C	LYS	B	247	56.852	12.983	66.024	1.00	74.82	C
ATOM	4522	O	LYS	B	247	57.855	12.626	65.394	1.00	74.48	O
ATOM	4524	N	LEU	B	248	56.029	13.966	65.638	1.00	74.77	N
ATOM	4525	CA	LEU	B	248	56.176	14.705	64.358	1.00	74.61	C
ATOM	4527	CB	LEU	B	248	54.871	14.604	63.575	1.00	74.37	C
ATOM	4530	CG	LEU	B	248	54.555	13.219	63.021	1.00	74.17	C
ATOM	4532	CD1	LEU	B	248	53.143	13.189	62.457	1.00	74.25	C
ATOM	4536	CD2	LEU	B	248	55.567	12.800	61.935	1.00	74.91	C
ATOM	4540	C	LEU	B	248	56.598	16.170	64.510	1.00	73.91	C
ATOM	4541	O	LEU	B	248	55.987	16.901	65.265	1.00	73.45	O
ATOM	4543	N	GLY	B	254	48.936	19.328	73.181	1.00	77.99	N
ATOM	4544	CA	GLY	B	254	48.713	19.228	71.730	1.00	77.76	C
ATOM	4547	C	GLY	B	254	49.841	18.596	70.904	1.00	77.93	C
ATOM	4548	O	GLY	B	254	50.200	19.145	69.859	1.00	78.38	O
ATOM	4550	N	GLU	B	255	50.361	17.435	71.349	1.00	77.65	N
ATOM	4551	CA	GLU	B	255	51.456	16.680	70.688	1.00	77.17	C
ATOM	4553	CB	GLU	B	255	52.171	15.730	71.676	1.00	77.20	C
ATOM	4556	CG	GLU	B	255	52.680	16.315	73.016	1.00	77.72	C
ATOM	4559	CD	GLU	B	255	52.676	15.300	74.193	1.00	77.55	C
ATOM	4560	OE1	GLU	B	255	52.880	14.078	73.957	1.00	76.95	O
ATOM	4561	OE2	GLU	B	255	52.456	15.714	75.367	1.00	76.25	O
ATOM	4562	C	GLU	B	255	50.870	15.826	69.551	1.00	77.31	C
ATOM	4563	O	GLU	B	255	49.748	15.323	69.686	1.00	78.20	O
ATOM	4565	N	VAL	B	256	51.621	15.642	68.451	1.00	76.73	N
ATOM	4566	CA	VAL	B	256	51.184	14.832	67.265	1.00	75.57	C
ATOM	4568	CB	VAL	B	256	51.012	15.687	65.974	1.00	74.99	C
ATOM	4570	CG1	VAL	B	256	50.371	14.879	64.828	1.00	73.24	C
ATOM	4574	CG2	VAL	B	256	50.172	16.923	66.279	1.00	75.06	C
ATOM	4578	C	VAL	B	256	52.175	13.699	66.997	1.00	74.81	C
ATOM	4579	O	VAL	B	256	53.387	13.893	67.021	1.00	74.53	O
ATOM	4581	N	TYR	B	257	51.623	12.527	66.716	1.00	74.52	N
ATOM	4582	CA	TYR	B	257	52.367	11.278	66.595	1.00	74.29	C
ATOM	4584	CB	TYR	B	257	52.022	10.342	67.773	1.00	74.06	C
ATOM	4587	CG	TYR	B	257	52.755	10.772	69.021	1.00	73.90	C
ATOM	4588	CD1	TYR	B	257	54.088	10.368	69.242	1.00	74.85	C
ATOM	4590	CE1	TYR	B	257	54.822	10.798	70.378	1.00	74.80	C
ATOM	4592	CZ	TYR	B	257	54.214	11.662	71.303	1.00	75.29	C
ATOM	4593	OH	TYR	B	257	54.941	12.068	72.400	1.00	74.81	O
ATOM	4595	CE2	TYR	B	257	52.883	12.098	71.099	1.00	74.76	C
ATOM	4597	CD2	TYR	B	257	52.165	11.646	69.950	1.00	74.28	C
ATOM	4599	C	TYR	B	257	52.033	10.660	65.255	1.00	74.33	C
ATOM	4600	O	TYR	B	257	50.946	10.893	64.700	1.00	74.16	O
ATOM	4602	N	GLU	B	258	52.988	9.916	64.711	1.00	74.51	N
ATOM	4603	CA	GLU	B	258	52.743	9.120	63.520	1.00	74.72	C
ATOM	4605	CB	GLU	B	258	54.028	8.801	62.730	1.00	74.77	C
ATOM	4608	CG	GLU	B	258	53.753	7.991	61.451	1.00	75.16	C
ATOM	4611	CD	GLU	B	258	54.916	7.954	60.456	1.00	75.83	C
ATOM	4612	OE1	GLU	B	258	55.411	9.061	60.075	1.00	74.05	O
ATOM	4613	OE2	GLU	B	258	55.303	6.812	60.031	1.00	77.61	O
ATOM	4614	C	GLU	B	258	52.104	7.872	64.046	1.00	74.19	C
ATOM	4615	O	GLU	B	258	52.585	7.321	65.022	1.00	74.34	O
ATOM	4617	N	GLY	B	259	51.003	7.461	63.427	1.00	74.27	N
ATOM	4618	CA	GLY	B	259	50.267	6.251	63.816	1.00	74.05	C
ATOM	4621	C	GLY	B	259	49.906	5.405	62.615	1.00	73.92	C
ATOM	4622	O	GLY	B	259	50.067	5.826	61.467	1.00	74.07	O
ATOM	4624	N	VAL	B	260	49.407	4.215	62.910	1.00	74.01	N
ATOM	4625	CA	VAL	B	260	49.023	3.212	61.925	1.00	74.31	C
ATOM	4627	CB	VAL	B	260	49.959	1.952	61.970	1.00	73.78	C
ATOM	4629	CG1	VAL	B	260	49.593	0.968	60.853	1.00	73.58	C
ATOM	4633	CG2	VAL	B	260	51.406	2.354	61.868	1.00	73.27	C
ATOM	4637	C	VAL	B	260	47.606	2.758	62.262	1.00	75.00	C
ATOM	4638	O	VAL	B	260	47.398	2.181	63.332	1.00	74.72	O
ATOM	4640	N	TRP	B	261	46.641	3.009	61.368	1.00	75.83	N
ATOM	4641	CA	TRP	B	261	45.303	2.381	61.462	1.00	76.03	C
ATOM	4643	CB	TRP	B	261	44.212	3.234	60.770	1.00	76.47	C
ATOM	4646	CG	TRP	B	261	42.792	2.999	61.258	1.00	76.40	C
ATOM	4647	CD1	TRP	B	261	42.312	1.907	61.913	1.00	77.18	C
ATOM	4649	NE1	TRP	B	261	40.975	2.059	62.188	1.00	76.69	N
ATOM	4651	CE2	TRP	B	261	40.560	3.258	61.687	1.00	76.04	C
ATOM	4652	CD2	TRP	B	261	41.679	3.875	61.091	1.00	76.69	C
ATOM	4653	CE3	TRP	B	261	41.512	5.139	60.508	1.00	78.52	C
ATOM	4655	CZ3	TRP	B	261	40.223	5.742	60.534	1.00	78.10	C
ATOM	4657	CH2	TRP	B	261	39.135	5.081	61.127	1.00	77.12	C
ATOM	4659	CZ2	TRP	B	261	39.287	3.851	61.712	1.00	76.77	C
ATOM	4661	C	TRP	B	261	45.418	0.944	60.893	1.00	76.08	C
ATOM	4662	O	TRP	B	261	45.013	0.658	59.755	1.00	76.05	O
ATOM	4664	N	LYS	B	262	46.005	0.073	61.733	1.00	76.08	N
ATOM	4665	CA	LYS	B	262	46.209	−1.384	61.527	1.00	75.79	C
ATOM	4667	CB	LYS	B	262	46.218	−2.122	62.894	1.00	75.92	C
ATOM	4670	CG	LYS	B	262	47.274	−1.763	63.996	1.00	75.88	C
ATOM	4673	CD	LYS	B	262	47.091	−2.742	65.220	1.00	76.26	C
ATOM	4676	CE	LYS	B	262	47.015	−2.075	66.614	1.00	76.17	C
ATOM	4679	NZ	LYS	B	262	46.269	−2.948	67.589	1.00	76.29	N
ATOM	4683	C	LYS	B	262	45.125	−2.063	60.666	1.00	75.58	C
ATOM	4684	O	LYS	B	262	45.442	−2.780	59.700	1.00	75.22	O
ATOM	4686	N	LYS	B	263	43.862	−1.809	61.058	1.00	75.43	N
ATOM	4687	CA	LYS	B	263	42.610	−2.343	60.434	1.00	75.22	C
ATOM	4689	CB	LYS	B	263	41.371	−1.672	61.094	1.00	75.29	C
ATOM	4692	CG	LYS	B	263	39.988	−1.938	60.457	1.00	75.46	C
ATOM	4695	CD	LYS	B	263	38.810	−1.709	61.457	1.00	75.52	C
ATOM	4698	CE	LYS	B	263	38.634	−2.877	62.459	1.00	76.30	C
ATOM	4701	NZ	LYS	B	263	37.203	−3.292	62.682	1.00	76.12	N
ATOM	4705	C	LYS	B	263	42.554	−2.148	58.918	1.00	74.43	C
ATOM	4706	O	LYS	B	263	42.212	−3.085	58.170	1.00	74.18	O
ATOM	4708	N	TYR	B	264	42.923	−0.936	58.497	1.00	73.31	N
ATOM	4709	CA	TYR	B	264	42.941	−0.541	57.097	1.00	72.28	C
ATOM	4711	CB	TYR	B	264	42.196	0.785	56.974	1.00	73.54	C
ATOM	4714	CG	TYR	B	264	40.779	0.744	57.526	1.00	74.52	C
ATOM	4715	CD1	TYR	B	264	39.743	0.084	56.831	1.00	75.51	C
ATOM	4717	CE1	TYR	B	264	38.422	0.065	57.338	1.00	74.65	C
ATOM	4719	CZ	TYR	B	264	38.142	0.697	58.542	1.00	74.09	C
ATOM	4720	OH	TYR	B	264	36.883	0.723	59.078	1.00	74.39	O
ATOM	4722	CE2	TYR	B	264	39.139	1.343	59.240	1.00	74.81	C
ATOM	4724	CD2	TYR	B	264	40.458	1.374	58.733	1.00	75.16	C
ATOM	4726	C	TYR	B	264	44.353	−0.432	56.468	1.00	71.56	C
ATOM	4727	O	TYR	B	264	44.480	0.121	55.358	1.00	71.76	O
ATOM	4729	N	SER	B	265	45.389	−0.954	57.146	1.00	69.99	N
ATOM	4730	CA	SER	B	265	46.770	−0.987	56.631	1.00	68.92	C
ATOM	4732	CB	SER	B	265	46.847	−2.022	55.504	1.00	68.35	C
ATOM	4735	OG	SER	B	265	48.186	−2.323	55.159	1.00	67.80	O
ATOM	4737	C	SER	B	265	47.263	0.429	56.192	1.00	67.95	C
ATOM	4738	O	SER	B	265	47.826	0.605	55.105	1.00	67.21	O
ATOM	4740	N	LEU	B	266	47.037	1.414	57.072	1.00	67.13	N
ATOM	4741	CA	LEU	B	266	47.051	2.855	56.724	1.00	67.09	C
ATOM	4743	CB	LEU	B	266	45.598	3.341	56.615	1.00	66.89	C
ATOM	4746	CG	LEU	B	266	45.310	4.839	56.477	1.00	66.36	C
ATOM	4748	CD1	LEU	B	266	45.916	5.323	55.221	1.00	66.40	C
ATOM	4752	CD2	LEU	B	266	43.815	5.120	56.465	1.00	66.34	C
ATOM	4756	C	LEU	B	266	47.812	3.731	57.747	1.00	66.82	C
ATOM	4757	O	LEU	B	266	47.629	3.568	58.948	1.00	66.59	O
ATOM	4759	N	THR	B	267	48.626	4.669	57.255	1.00	66.40	N
ATOM	4760	CA	THR	B	267	49.396	5.604	58.101	1.00	66.25	C
ATOM	4762	CB	THR	B	267	50.786	5.892	57.476	1.00	66.40	C
ATOM	4764	OG1	THR	B	267	51.426	4.657	57.129	1.00	66.77	O
ATOM	4766	CG2	THR	B	267	51.754	6.539	58.494	1.00	66.42	C
ATOM	4770	C	THR	B	267	48.657	6.926	58.333	1.00	65.66	C
ATOM	4771	O	THR	B	267	48.231	7.601	57.388	1.00	65.10	O
ATOM	4773	N	VAL	B	268	48.562	7.303	59.599	1.00	65.42	N
ATOM	4774	CA	VAL	B	268	47.797	8.470	60.027	1.00	65.52	C
ATOM	4776	CB	VAL	B	268	46.483	8.090	60.724	1.00	65.19	C
ATOM	4778	CG1	VAL	B	268	45.506	7.529	59.714	1.00	64.85	C
ATOM	4782	CG2	VAL	B	268	46.706	7.085	61.876	1.00	65.55	C
ATOM	4786	C	VAL	B	268	48.601	9.325	60.977	1.00	66.07	C
ATOM	4787	O	VAL	B	268	49.564	8.849	61.611	1.00	66.16	O
ATOM	4789	N	ALA	B	269	48.193	10.590	61.047	1.00	66.44	N
ATOM	4790	CA	ALA	B	269	48.684	11.538	62.023	1.00	66.73	C
ATOM	4792	CB	ALA	B	269	48.835	12.899	61.412	1.00	66.48	C
ATOM	4796	C	ALA	B	269	47.637	11.547	63.141	1.00	67.56	C
ATOM	4797	O	ALA	B	269	46.419	11.624	62.889	1.00	66.88	O
ATOM	4799	N	VAL	B	270	48.122	11.464	64.373	1.00	68.46	N
ATOM	4800	CA	VAL	B	270	47.264	11.350	65.529	1.00	69.21	C
ATOM	4802	CB	VAL	B	270	47.498	10.020	66.294	1.00	69.47	C
ATOM	4804	CG1	VAL	B	270	46.556	9.924	67.520	1.00	70.10	C
ATOM	4808	CG2	VAL	B	270	47.285	8.833	65.354	1.00	68.98	C
ATOM	4812	C	VAL	B	270	47.598	12.513	66.388	1.00	69.41	C
ATOM	4813	O	VAL	B	270	48.689	12.566	66.916	1.00	68.78	O
ATOM	4815	N	LYS	B	271	46.672	13.457	66.486	1.00	70.93	N
ATOM	4816	CA	LYS	B	271	46.834	14.594	67.389	1.00	72.33	C
ATOM	4818	CB	LYS	B	271	46.197	15.881	66.872	1.00	71.32	C
ATOM	4821	CG	LYS	B	271	46.305	16.998	67.905	1.00	71.61	C
ATOM	4824	CD	LYS	B	271	46.396	18.372	67.267	1.00	71.68	C
ATOM	4827	CE	LYS	B	271	46.395	19.461	68.330	1.00	69.12	C
ATOM	4830	NZ	LYS	B	271	45.648	20.556	67.814	1.00	64.94	N
ATOM	4834	C	LYS	B	271	46.258	14.187	68.734	1.00	73.84	C
ATOM	4835	O	LYS	B	271	45.140	13.710	68.799	1.00	73.97	O
ATOM	4837	N	THR	B	272	47.036	14.426	69.786	1.00	76.02	N
ATOM	4838	CA	THR	B	272	46.780	13.915	71.107	1.00	77.93	C
ATOM	4840	CB	THR	B	272	47.803	12.776	71.379	1.00	78.19	C
ATOM	4842	OG1	THR	B	272	47.194	11.783	72.221	1.00	79.95	O
ATOM	4844	CG2	THR	B	272	49.100	13.238	72.131	1.00	77.87	C
ATOM	4848	C	THR	B	272	46.816	15.027	72.165	1.00	79.55	C
ATOM	4849	O	THR	B	272	47.117	16.181	71.858	1.00	79.69	O
ATOM	4851	N	LEU	B	273	46.512	14.660	73.408	1.00	81.73	N
ATOM	4852	CA	LEU	B	273	46.434	15.622	74.511	1.00	83.33	C
ATOM	4854	CB	LEU	B	273	44.963	15.851	74.901	1.00	83.12	C
ATOM	4857	CG	LEU	B	273	44.548	17.212	75.476	1.00	82.38	C
ATOM	4859	CD1	LEU	B	273	45.077	18.405	74.660	1.00	82.39	C
ATOM	4863	CD2	LEU	B	273	43.022	17.264	75.584	1.00	82.43	C
ATOM	4867	C	LEU	B	273	47.290	15.181	75.720	1.00	84.40	C
ATOM	4868	O	LEU	B	273	47.252	13.984	76.120	1.00	84.36	O
ATOM	4870	N	LYS	B	274	48.053	16.167	76.255	1.00	85.64	N
ATOM	4871	CA	LYS	B	274	48.922	16.054	77.454	1.00	86.47	C
ATOM	4873	CB	LYS	B	274	49.579	17.415	77.801	1.00	86.83	C
ATOM	4876	CG	LYS	B	274	50.553	18.003	76.747	1.00	87.38	C
ATOM	4879	CD	LYS	B	274	50.590	19.553	76.777	1.00	87.23	C
ATOM	4882	CE	LYS	B	274	51.404	20.146	75.618	1.00	87.22	C
ATOM	4885	NZ	LYS	B	274	51.299	21.633	75.568	1.00	86.43	N
ATOM	4889	C	LYS	B	274	48.070	15.607	78.647	1.00	87.79	C
ATOM	4890	O	LYS	B	274	47.018	16.208	78.896	1.00	87.91	O
ATOM	4892	N	GLU	B	275	48.562	14.617	79.399	1.00	88.93	N
ATOM	4893	CA	GLU	B	275	47.720	13.719	80.238	1.00	90.06	C
ATOM	4895	CB	GLU	B	275	48.584	12.678	81.008	1.00	90.30	C
ATOM	4898	CG	GLU	B	275	49.502	11.795	80.147	1.00	91.26	C
ATOM	4901	CD	GLU	B	275	48.806	11.208	78.923	1.00	92.58	C
ATOM	4902	OE1	GLU	B	275	48.158	10.143	79.080	1.00	94.14	O
ATOM	4903	OE2	GLU	B	275	48.886	11.823	77.821	1.00	91.41	O
ATOM	4904	C	GLU	B	275	46.730	14.404	81.206	1.00	90.45	C
ATOM	4905	O	GLU	B	275	47.062	14.690	82.368	1.00	90.70	O
ATOM	4907	N	ASP	B	276	45.527	14.681	80.675	1.00	90.77	N
ATOM	4908	CA	ASP	B	276	44.353	15.163	81.429	1.00	90.66	C
ATOM	4910	CB	ASP	B	276	43.916	14.107	82.472	1.00	90.82	C
ATOM	4913	CG	ASP	B	276	43.807	12.673	81.872	1.00	91.31	C
ATOM	4914	OD1	ASP	B	276	43.534	12.535	80.653	1.00	92.61	O
ATOM	4915	OD2	ASP	B	276	43.986	11.629	82.541	1.00	90.49	O
ATOM	4916	C	ASP	B	276	44.575	16.578	82.019	1.00	90.66	C
ATOM	4917	O	ASP	B	276	44.516	16.787	83.237	1.00	90.58	O
ATOM	4919	N	THR	B	277	44.827	17.528	81.110	1.00	90.64	N
ATOM	4920	CA	THR	B	277	45.103	18.950	81.415	1.00	90.55	C
ATOM	4922	CB	THR	B	277	46.322	19.454	80.510	1.00	90.81	C
ATOM	4924	OG1	THR	B	277	47.362	18.465	80.488	1.00	91.55	O
ATOM	4926	CG2	THR	B	277	47.070	20.675	81.072	1.00	90.67	C
ATOM	4930	C	THR	B	277	43.803	19.778	81.191	1.00	90.34	C
ATOM	4931	O	THR	B	277	42.723	19.209	80.980	1.00	90.06	O
ATOM	4933	N	MET	B	278	43.915	21.106	81.303	1.00	90.13	N
ATOM	4934	CA	MET	B	278	42.851	22.098	80.958	1.00	89.77	C
ATOM	4936	CB	MET	B	278	43.210	23.466	81.571	1.00	89.80	C
ATOM	4939	CG	MET	B	278	44.410	24.181	80.906	1.00	90.14	C
ATOM	4942	SD	MET	B	278	44.666	25.819	81.565	1.00	91.00	S
ATOM	4943	CE	MET	B	278	43.366	26.812	80.752	1.00	91.23	C
ATOM	4947	C	MET	B	278	42.516	22.348	79.460	1.00	89.24	C
ATOM	4948	O	MET	B	278	41.521	23.028	79.154	1.00	89.00	O
ATOM	4950	N	GLU	B	279	43.325	21.817	78.537	1.00	88.58	N
ATOM	4951	CA	GLU	B	279	43.235	22.154	77.102	1.00	87.74	C
ATOM	4953	CB	GLU	B	279	44.604	21.859	76.411	1.00	87.95	C
ATOM	4956	CG	GLU	B	279	45.829	22.642	76.924	1.00	88.19	C
ATOM	4959	CD	GLU	B	279	47.176	21.917	76.715	1.00	88.45	C
ATOM	4960	OE1	GLU	B	279	47.477	21.432	75.584	1.00	89.31	O
ATOM	4961	OE2	GLU	B	279	47.952	21.826	77.703	1.00	89.33	O
ATOM	4962	C	GLU	B	279	42.078	21.407	76.373	1.00	86.89	C
ATOM	4963	O	GLU	B	279	42.118	21.256	75.144	1.00	87.26	O
ATOM	4965	N	VAL	B	280	41.025	21.002	77.092	1.00	85.58	N
ATOM	4966	CA	VAL	B	280	40.112	19.954	76.618	1.00	84.75	C
ATOM	4968	CB	VAL	B	280	39.455	19.139	77.767	1.00	84.63	C
ATOM	4970	CG1	VAL	B	280	38.671	17.938	77.194	1.00	84.05	C
ATOM	4974	CG2	VAL	B	280	40.502	18.668	78.779	1.00	84.77	C
ATOM	4978	C	VAL	B	280	39.015	20.539	75.764	1.00	82.91	C
ATOM	4979	O	VAL	B	280	38.838	20.110	74.644	1.00	82.80	O
ATOM	4981	N	GLU	B	281	38.266	21.496	76.304	1.00	81.34	N
ATOM	4982	CA	GLU	B	281	37.148	22.118	75.568	1.00	79.94	C
ATOM	4984	CB	GLU	B	281	36.496	23.257	76.373	1.00	79.79	C
ATOM	4987	CG	GLU	B	281	35.821	22.849	77.687	1.00	79.41	C
ATOM	4990	CD	GLU	B	281	34.421	22.232	77.553	1.00	78.70	C
ATOM	4991	OE1	GLU	B	281	34.014	21.806	76.454	1.00	78.74	O
ATOM	4992	OE2	GLU	B	281	33.715	22.153	78.584	1.00	77.12	O
ATOM	4993	C	GLU	B	281	37.597	22.644	74.197	1.00	79.36	C
ATOM	4994	O	GLU	B	281	36.825	22.579	73.251	1.00	79.15	O
ATOM	4996	N	GLU	B	282	38.840	23.145	74.124	1.00	78.53	N
ATOM	4997	CA	GLU	B	282	39.519	23.584	72.877	1.00	78.25	C
ATOM	4999	CB	GLU	B	282	40.877	24.243	73.215	1.00	78.32	C
ATOM	5002	CG	GLU	B	282	40.768	25.700	73.658	1.00	80.39	C
ATOM	5005	CD	GLU	B	282	40.198	26.611	72.569	1.00	84.05	C
ATOM	5006	OE1	GLU	B	282	40.394	26.303	71.354	1.00	86.18	O
ATOM	5007	OE2	GLU	B	282	39.527	27.618	72.925	1.00	85.80	O
ATOM	5008	C	GLU	B	282	39.755	22.500	71.813	1.00	76.92	C
ATOM	5009	O	GLU	B	282	39.569	22.740	70.621	1.00	76.75	O
ATOM	5011	N	PHE	B	283	40.224	21.342	72.268	1.00	75.59	N
ATOM	5012	CA	PHE	B	283	40.312	20.102	71.481	1.00	74.41	C
ATOM	5014	CB	PHE	B	283	40.786	18.973	72.403	1.00	74.84	C
ATOM	5017	CG	PHE	B	283	41.629	17.962	71.740	1.00	75.42	C
ATOM	5018	CD1	PHE	B	283	42.965	18.240	71.470	1.00	76.41	C
ATOM	5020	CE1	PHE	B	283	43.790	17.273	70.855	1.00	76.45	C
ATOM	5022	CZ	PHE	B	283	43.269	16.026	70.522	1.00	76.08	C
ATOM	5024	CE2	PHE	B	283	41.937	15.729	70.799	1.00	76.63	C
ATOM	5026	CD2	PHE	B	283	41.119	16.699	71.419	1.00	77.17	C
ATOM	5028	C	PHE	B	283	38.954	19.714	70.859	1.00	73.30	C
ATOM	5029	O	PHE	B	283	38.866	19.408	69.674	1.00	73.03	O
ATOM	5031	N	LEU	B	284	37.902	19.754	71.673	1.00	72.05	N
ATOM	5032	CA	LEU	B	284	36.526	19.531	71.208	1.00	71.23	C
ATOM	5034	CB	LEU	B	284	35.534	19.431	72.391	1.00	71.20	C
ATOM	5037	CG	LEU	B	284	35.405	18.117	73.194	1.00	71.29	C
ATOM	5039	CD1	LEU	B	284	36.622	17.826	74.085	1.00	71.13	C
ATOM	5043	CD2	LEU	B	284	34.138	18.161	74.068	1.00	71.08	C
ATOM	5047	C	LEU	B	284	36.015	20.559	70.154	1.00	71.00	C
ATOM	5048	O	LEU	B	284	35.242	20.171	69.280	1.00	71.12	O
ATOM	5050	N	LYS	B	285	36.415	21.841	70.235	1.00	70.68	N
ATOM	5051	CA	LYS	B	285	36.076	22.839	69.194	1.00	70.24	C
ATOM	5053	CB	LYS	B	285	36.551	24.255	69.535	1.00	70.03	C
ATOM	5056	CG	LYS	B	285	35.880	24.872	70.748	1.00	70.27	C
ATOM	5059	CD	LYS	B	285	36.117	26.402	70.884	1.00	69.97	C
ATOM	5062	CE	LYS	B	285	35.119	27.245	70.056	1.00	69.55	C
ATOM	5065	NZ	LYS	B	285	35.227	28.732	70.307	1.00	69.51	N
ATOM	5069	C	LYS	B	285	36.714	22.378	67.879	1.00	70.17	C
ATOM	5070	O	LYS	B	285	35.993	22.133	66.886	1.00	70.44	O
ATOM	5072	N	GLU	B	286	38.041	22.192	67.918	1.00	69.15	N
ATOM	5073	CA	GLU	B	286	38.830	21.672	66.799	1.00	68.54	C
ATOM	5075	CB	GLU	B	286	40.273	21.413	67.255	1.00	68.67	C
ATOM	5078	CG	GLU	B	286	41.242	20.889	66.203	1.00	68.83	C
ATOM	5081	CD	GLU	B	286	42.683	20.788	66.696	1.00	69.05	C
ATOM	5082	OE1	GLU	B	286	42.968	20.966	67.912	1.00	70.57	O
ATOM	5083	OE2	GLU	B	286	43.563	20.519	65.854	1.00	69.97	O
ATOM	5084	C	GLU	B	286	38.221	20.404	66.167	1.00	68.23	C
ATOM	5085	O	GLU	B	286	37.965	20.381	64.975	1.00	68.32	O
ATOM	5087	N	ALA	B	287	37.948	19.378	66.963	1.00	67.62	N
ATOM	5088	CA	ALA	B	287	37.365	18.125	66.423	1.00	67.12	C
ATOM	5090	CB	ALA	B	287	37.233	17.064	67.512	1.00	66.71	C
ATOM	5094	C	ALA	B	287	36.018	18.361	65.724	1.00	66.31	C
ATOM	5095	O	ALA	B	287	35.804	17.901	64.613	1.00	66.49	O
ATOM	5097	N	ALA	B	288	35.143	19.124	66.358	1.00	65.71	N
ATOM	5098	CA	ALA	B	288	33.847	19.497	65.763	1.00	65.18	C
ATOM	5100	CB	ALA	B	288	33.025	20.351	66.759	1.00	65.49	C
ATOM	5104	C	ALA	B	288	33.970	20.242	64.431	1.00	64.17	C
ATOM	5105	O	ALA	B	288	33.212	19.960	63.495	1.00	63.27	O
ATOM	5107	N	VAL	B	289	34.908	21.196	64.385	1.00	63.11	N
ATOM	5108	CA	VAL	B	289	35.193	21.987	63.182	1.00	62.82	C
ATOM	5110	CB	VAL	B	289	36.317	23.069	63.430	1.00	63.30	C
ATOM	5112	CG1	VAL	B	289	36.849	23.716	62.117	1.00	63.73	C
ATOM	5116	CG2	VAL	B	289	35.806	24.187	64.358	1.00	62.91	C
ATOM	5120	C	VAL	B	289	35.576	21.096	62.026	1.00	62.35	C
ATOM	5121	O	VAL	B	289	35.101	21.297	60.927	1.00	61.52	O
ATOM	5123	N	MET	B	290	36.415	20.102	62.321	1.00	62.83	N
ATOM	5124	CA	MET	B	290	36.942	19.129	61.349	1.00	62.80	C
ATOM	5126	CB	MET	B	290	38.136	18.372	61.947	1.00	62.65	C
ATOM	5129	CG	MET	B	290	39.351	19.253	62.368	1.00	63.93	C
ATOM	5132	SD	MET	B	290	40.994	18.621	61.814	1.00	68.60	S
ATOM	5133	CE	MET	B	290	41.333	17.490	62.871	1.00	68.54	C
ATOM	5137	C	MET	B	290	35.906	18.131	60.840	1.00	61.96	C
ATOM	5138	O	MET	B	290	36.104	17.547	59.760	1.00	62.57	O
ATOM	5140	N	LYS	B	291	34.834	17.908	61.616	1.00	61.17	N
ATOM	5141	CA	LYS	B	291	33.659	17.115	61.175	1.00	60.27	C
ATOM	5143	CB	LYS	B	291	32.762	16.722	62.351	1.00	59.69	C
ATOM	5146	CG	LYS	B	291	33.405	15.873	63.427	1.00	59.63	C
ATOM	5149	CD	LYS	B	291	32.538	15.794	64.699	1.00	60.23	C
ATOM	5152	CE	LYS	B	291	33.222	14.982	65.824	1.00	60.65	C
ATOM	5155	NZ	LYS	B	291	32.474	15.027	67.119	1.00	59.38	N
ATOM	5159	C	LYS	B	291	32.819	17.874	60.151	1.00	59.66	C
ATOM	5160	O	LYS	B	291	32.310	17.266	59.238	1.00	59.59	O
ATOM	5162	N	GLU	B	292	32.696	19.197	60.299	1.00	59.75	N
ATOM	5163	CA	GLU	B	292	31.893	20.058	59.407	1.00	60.03	C
ATOM	5165	CB	GLU	B	292	31.372	21.292	60.201	1.00	60.78	C
ATOM	5168	CG	GLU	B	292	30.267	20.978	61.214	1.00	63.30	C
ATOM	5171	CD	GLU	B	292	29.051	20.319	60.559	1.00	66.86	C
ATOM	5172	OE1	GLU	B	292	28.521	20.912	59.574	1.00	68.26	O
ATOM	5173	OE2	GLU	B	292	28.659	19.199	60.994	1.00	67.37	O
ATOM	5174	C	GLU	B	292	32.565	20.547	58.115	1.00	59.79	C
ATOM	5175	O	GLU	B	292	31.937	21.314	57.348	1.00	60.02	O
ATOM	5177	N	ILE	B	293	33.817	20.140	57.870	1.00	59.28	N
ATOM	5178	CA	ILE	B	293	34.606	20.641	56.731	1.00	58.88	C
ATOM	5180	CB	ILE	B	293	35.615	21.691	57.150	1.00	58.86	C
ATOM	5182	CG1	ILE	B	293	36.639	21.136	58.121	1.00	58.71	C
ATOM	5185	CD1	ILE	B	293	37.583	22.215	58.633	1.00	59.08	C
ATOM	5189	CG2	ILE	B	293	34.871	22.933	57.710	1.00	60.28	C
ATOM	5193	C	ILE	B	293	35.293	19.552	55.939	1.00	57.99	C
ATOM	5194	O	ILE	B	293	35.839	18.596	56.511	1.00	57.96	O
ATOM	5196	N	LYS	B	294	35.223	19.723	54.613	1.00	56.92	N
ATOM	5197	CA	LYS	B	294	35.668	18.738	53.625	1.00	56.22	C
ATOM	5199	CB	LYS	B	294	34.612	17.629	53.439	1.00	56.16	C
ATOM	5202	CG	LYS	B	294	34.927	16.475	52.462	1.00	55.99	C
ATOM	5205	CD	LYS	B	294	34.259	15.139	52.974	1.00	57.03	C
ATOM	5208	CE	LYS	B	294	34.386	13.885	52.043	1.00	56.31	C
ATOM	5211	NZ	LYS	B	294	33.211	13.792	51.129	1.00	56.01	N
ATOM	5215	C	LYS	B	294	35.967	19.542	52.337	1.00	54.90	C
ATOM	5216	O	LYS	B	294	35.079	20.130	51.702	1.00	53.43	O
ATOM	5218	N	HIS	B	295	37.262	19.604	52.039	1.00	54.29	N
ATOM	5219	CA	HIS	B	295	37.804	20.192	50.821	1.00	53.92	C
ATOM	5221	CB	HIS	B	295	38.096	21.644	51.096	1.00	53.38	C
ATOM	5224	CG	HIS	B	295	38.482	22.394	49.883	1.00	53.43	C
ATOM	5225	ND1	HIS	B	295	39.783	22.447	49.438	1.00	52.74	N
ATOM	5227	CE1	HIS	B	295	39.830	23.161	48.332	1.00	54.00	C
ATOM	5229	NE2	HIS	B	295	38.604	23.574	48.048	1.00	54.59	N
ATOM	5231	CD2	HIS	B	295	37.739	23.091	48.993	1.00	53.24	C
ATOM	5233	C	HIS	B	295	39.105	19.432	50.431	1.00	53.86	C
ATOM	5234	O	HIS	B	295	39.801	18.952	51.332	1.00	53.84	O
ATOM	5236	N	PRO	B	296	39.467	19.319	49.144	1.00	53.90	N
ATOM	5237	CA	PRO	B	296	40.706	18.590	48.771	1.00	53.93	C
ATOM	5239	CB	PRO	B	296	40.670	18.604	47.230	1.00	53.67	C
ATOM	5242	CG	PRO	B	296	39.307	18.852	46.896	1.00	53.33	C
ATOM	5245	CD	PRO	B	296	38.776	19.798	47.928	1.00	53.79	C
ATOM	5248	C	PRO	B	296	42.027	19.177	49.221	1.00	53.85	C
ATOM	5249	O	PRO	B	296	43.019	18.576	49.013	1.00	53.95	O
ATOM	5250	N	ASN	B	297	42.020	20.365	49.788	1.00	55.34	N
ATOM	5251	CA	ASN	B	297	43.218	21.103	50.217	1.00	56.36	C
ATOM	5253	CB	ASN	B	297	43.438	22.343	49.329	1.00	56.22	C
ATOM	5256	CG	ASN	B	297	43.525	21.988	47.856	1.00	56.12	C
ATOM	5257	OD1	ASN	B	297	42.500	21.876	47.190	1.00	55.87	O
ATOM	5258	ND2	ASN	B	297	44.736	21.800	47.351	1.00	55.34	N
ATOM	5261	C	ASN	B	297	43.156	21.471	51.710	1.00	56.46	C
ATOM	5262	O	ASN	B	297	43.820	22.407	52.137	1.00	56.41	O
ATOM	5264	N	LEU	B	298	42.362	20.715	52.481	1.00	56.71	N
ATOM	5265	CA	LEU	B	298	42.359	20.763	53.930	1.00	56.79	C
ATOM	5267	CB	LEU	B	298	41.026	21.246	54.423	1.00	56.14	C
ATOM	5270	CG	LEU	B	298	40.658	22.630	53.993	1.00	56.05	C
ATOM	5272	CD1	LEU	B	298	39.256	22.879	54.438	1.00	57.74	C
ATOM	5276	CD2	LEU	B	298	41.626	23.707	54.573	1.00	57.13	C
ATOM	5280	C	LEU	B	298	42.586	19.352	54.414	1.00	57.67	C
ATOM	5281	O	LEU	B	298	41.859	18.440	53.996	1.00	57.07	O
ATOM	5283	N	VAL	B	299	43.593	19.169	55.276	1.00	59.06	N
ATOM	5284	CA	VAL	B	299	43.886	17.826	55.869	1.00	60.00	C
ATOM	5286	CB	VAL	B	299	45.078	17.814	56.882	1.00	59.76	C
ATOM	5288	CG1	VAL	B	299	44.963	18.914	57.870	1.00	64.35	C
ATOM	5292	CG2	VAL	B	299	45.129	16.539	57.678	1.00	59.64	C
ATOM	5296	C	VAL	B	299	42.602	17.305	56.477	1.00	60.10	C
ATOM	5297	O	VAL	B	299	41.877	18.052	57.106	1.00	60.50	O
ATOM	5299	N	GLN	B	300	42.297	16.047	56.204	1.00	61.87	N
ATOM	5300	CA	GLN	B	300	40.955	15.473	56.399	1.00	62.49	C
ATOM	5302	CB	GLN	B	300	40.507	14.660	55.169	1.00	61.97	C
ATOM	5305	CG	GLN	B	300	39.081	14.054	55.300	1.00	62.54	C
ATOM	5308	CD	GLN	B	300	37.958	15.033	55.030	1.00	63.67	C
ATOM	5309	OE1	GLN	B	300	37.810	15.493	53.892	1.00	67.89	O
ATOM	5310	NE2	GLN	B	300	37.122	15.301	56.038	1.00	60.56	N
ATOM	5313	C	GLN	B	300	40.889	14.629	57.676	1.00	63.05	C
ATOM	5314	O	GLN	B	300	41.739	13.773	57.912	1.00	61.84	O
ATOM	5316	N	LEU	B	301	39.833	14.885	58.453	1.00	64.73	N
ATOM	5317	CA	LEU	B	301	39.482	14.089	59.604	1.00	65.54	C
ATOM	5319	CB	LEU	B	301	38.363	14.768	60.361	1.00	65.78	C
ATOM	5322	CG	LEU	B	301	37.798	14.077	61.611	1.00	67.12	C
ATOM	5324	CD1	LEU	B	301	38.899	13.861	62.670	1.00	69.43	C
ATOM	5328	CD2	LEU	B	301	36.615	14.917	62.183	1.00	67.01	C
ATOM	5332	C	LEU	B	301	39.009	12.718	59.146	1.00	66.39	C
ATOM	5333	O	LEU	B	301	38.188	12.610	58.231	1.00	66.26	O
ATOM	5335	N	LEU	B	302	39.557	11.691	59.786	1.00	67.35	N
ATOM	5336	CA	LEU	B	302	39.168	10.303	59.597	1.00	68.11	C
ATOM	5338	CB	LEU	B	302	40.405	9.477	59.260	1.00	68.69	C
ATOM	5341	CG	LEU	B	302	41.315	9.944	58.133	1.00	69.48	C
ATOM	5343	CD1	LEU	B	302	42.592	9.098	58.153	1.00	69.38	C
ATOM	5347	CD2	LEU	B	302	40.570	9.817	56.786	1.00	70.13	C
ATOM	5351	C	LEU	B	302	38.533	9.658	60.828	1.00	68.40	C
ATOM	5352	O	LEU	B	302	37.843	8.650	60.694	1.00	68.99	O
ATOM	5354	N	GLY	B	303	38.817	10.160	62.021	1.00	68.75	N
ATOM	5355	CA	GLY	B	303	38.275	9.549	63.231	1.00	69.49	C
ATOM	5358	C	GLY	B	303	38.666	10.295	64.476	1.00	70.27	C
ATOM	5359	O	GLY	B	303	39.460	11.249	64.410	1.00	70.16	O
ATOM	5361	N	VAL	B	304	38.072	9.890	65.596	1.00	71.26	N
ATOM	5362	CA	VAL	B	304	38.339	10.511	66.914	1.00	72.27	C
ATOM	5364	CB	VAL	B	304	37.415	11.765	67.239	1.00	72.22	C
ATOM	5366	CG1	VAL	B	304	37.713	12.972	66.328	1.00	71.24	C
ATOM	5370	CG2	VAL	B	304	35.913	11.397	67.209	1.00	71.95	C
ATOM	5374	C	VAL	B	304	38.147	9.512	68.034	1.00	73.39	C
ATOM	5375	O	VAL	B	304	37.552	8.443	67.827	1.00	73.23	O
ATOM	5377	N	CYS	B	305	38.653	9.877	69.213	1.00	75.11	N
ATOM	5378	CA	CYS	B	305	38.310	9.202	70.487	1.00	76.71	C
ATOM	5380	CB	CYS	B	305	39.469	8.304	70.923	1.00	76.71	C
ATOM	5383	SG	CYS	B	305	40.061	7.284	69.567	1.00	80.06	S
ATOM	5385	C	CYS	B	305	37.991	10.242	71.563	1.00	76.81	C
ATOM	5386	O	CYS	B	305	38.886	10.647	72.298	1.00	76.76	O
ATOM	5388	N	THR	B	306	36.729	10.686	71.625	1.00	77.27	N
ATOM	5389	CA	THR	B	306	36.302	11.767	72.552	1.00	77.61	C
ATOM	5391	CB	THR	B	306	35.975	13.086	71.769	1.00	77.86	C
ATOM	5393	OG1	THR	B	306	34.943	12.872	70.795	1.00	77.79	O
ATOM	5395	CG2	THR	B	306	37.209	13.576	70.950	1.00	77.27	C
ATOM	5399	C	THR	B	306	35.195	11.350	73.553	1.00	78.19	C
ATOM	5400	O	THR	B	306	34.187	12.049	73.742	1.00	78.09	O
ATOM	5402	N	ARG	B	307	35.434	10.193	74.185	1.00	78.84	N
ATOM	5403	CA	ARG	B	307	34.690	9.699	75.354	1.00	79.28	C
ATOM	5405	CB	ARG	B	307	33.957	8.374	75.040	1.00	79.16	C
ATOM	5408	CG	ARG	B	307	32.560	8.541	74.401	1.00	79.65	C
ATOM	5411	CD	ARG	B	307	32.486	8.360	72.864	1.00	79.25	C
ATOM	5414	NE	ARG	B	307	31.243	8.928	72.288	1.00	78.87	N
ATOM	5416	CZ	ARG	B	307	30.468	8.387	71.319	1.00	77.88	C
ATOM	5417	NH1	ARG	B	307	30.743	7.199	70.748	1.00	77.45	N
ATOM	5420	NH2	ARG	B	307	29.382	9.058	70.917	1.00	77.41	N
ATOM	5423	C	ARG	B	307	35.683	9.529	76.513	1.00	79.49	C
ATOM	5424	O	ARG	B	307	35.660	10.323	77.465	1.00	79.71	O
ATOM	5426	N	GLU	B	308	36.579	8.540	76.393	1.00	79.48	N
ATOM	5427	CA	GLU	B	308	37.615	8.276	77.411	1.00	79.30	C
ATOM	5429	CB	GLU	B	308	38.102	6.807	77.455	1.00	79.29	C
ATOM	5432	CG	GLU	B	308	37.172	5.716	76.913	1.00	79.56	C
ATOM	5435	CD	GLU	B	308	37.372	5.446	75.423	1.00	79.93	C
ATOM	5436	OE1	GLU	B	308	37.704	6.396	74.674	1.00	80.96	O
ATOM	5437	OE2	GLU	B	308	37.198	4.291	74.994	1.00	79.29	O
ATOM	5438	C	GLU	B	308	38.805	9.194	77.061	1.00	79.29	C
ATOM	5439	O	GLU	B	308	39.079	9.383	75.869	1.00	79.13	O
ATOM	5441	N	PRO	B	309	39.486	9.782	78.058	1.00	79.04	N
ATOM	5442	CA	PRO	B	309	40.865	10.284	77.868	1.00	78.98	C
ATOM	5444	CB	PRO	B	309	41.143	11.049	79.174	1.00	78.80	C
ATOM	5447	CG	PRO	B	309	39.823	11.298	79.759	1.00	78.63	C
ATOM	5450	CD	PRO	B	309	38.989	10.114	79.403	1.00	78.87	C
ATOM	5453	C	PRO	B	309	41.898	9.149	77.675	1.00	78.88	C
ATOM	5454	O	PRO	B	309	41.570	7.995	77.959	1.00	78.52	O
ATOM	5455	N	PRO	B	310	43.137	9.450	77.258	1.00	78.99	N
ATOM	5456	CA	PRO	B	310	43.547	10.648	76.466	1.00	79.02	C
ATOM	5458	CB	PRO	B	310	45.081	10.508	76.412	1.00	79.17	C
ATOM	5461	CG	PRO	B	310	45.358	9.153	77.021	1.00	79.45	C
ATOM	5464	CD	PRO	B	310	44.271	8.926	78.033	1.00	79.06	C
ATOM	5467	C	PRO	B	310	43.008	10.798	75.027	1.00	78.50	C
ATOM	5468	O	PRO	B	310	43.185	9.906	74.193	1.00	78.68	O
ATOM	5469	N	PHE	B	311	42.457	11.967	74.723	1.00	77.83	N
ATOM	5470	CA	PHE	B	311	41.713	12.178	73.478	1.00	77.56	C
ATOM	5472	CB	PHE	B	311	40.849	13.464	73.554	1.00	78.13	C
ATOM	5475	CG	PHE	B	311	39.906	13.495	74.763	1.00	78.77	C
ATOM	5476	CD1	PHE	B	311	39.007	12.439	74.999	1.00	79.88	C
ATOM	5478	CE1	PHE	B	311	38.142	12.430	76.120	1.00	79.52	C
ATOM	5480	CZ	PHE	B	311	38.180	13.483	77.031	1.00	79.10	C
ATOM	5482	CE2	PHE	B	311	39.083	14.538	76.820	1.00	78.86	C
ATOM	5484	CD2	PHE	B	311	39.944	14.542	75.689	1.00	78.70	C
ATOM	5486	C	PHE	B	311	42.619	12.144	72.220	1.00	76.93	C
ATOM	5487	O	PHE	B	311	43.850	12.305	72.298	1.00	77.27	O
ATOM	5489	N	TYR	B	312	41.988	11.877	71.078	1.00	75.60	N
ATOM	5490	CA	TYR	B	312	42.671	11.619	69.810	1.00	74.16	C
ATOM	5492	CB	TYR	B	312	42.716	10.106	69.500	1.00	74.48	C
ATOM	5495	CG	TYR	B	312	43.797	9.223	70.111	1.00	74.54	C
ATOM	5496	CD1	TYR	B	312	44.983	9.726	70.698	1.00	74.24	C
ATOM	5498	CE1	TYR	B	312	45.946	8.839	71.221	1.00	74.30	C
ATOM	5500	CZ	TYR	B	312	45.713	7.452	71.129	1.00	74.47	C
ATOM	5501	OH	TYR	B	312	46.575	6.503	71.609	1.00	74.29	O
ATOM	5503	CE2	TYR	B	312	44.570	6.971	70.553	1.00	73.85	C
ATOM	5505	CD2	TYR	B	312	43.640	7.841	70.044	1.00	73.73	C
ATOM	5507	C	TYR	B	312	41.869	12.238	68.680	1.00	72.73	C
ATOM	5508	O	TYR	B	312	40.640	12.100	68.647	1.00	72.52	O
ATOM	5510	N	ILE	B	313	42.580	12.868	67.750	1.00	70.96	N
ATOM	5511	CA	ILE	B	313	42.081	13.184	66.422	1.00	69.57	C
ATOM	5513	CB	ILE	B	313	42.190	14.692	66.183	1.00	69.43	C
ATOM	5515	CG1	ILE	B	313	41.189	15.478	67.065	1.00	68.90	C
ATOM	5518	CD1	ILE	B	313	41.571	16.948	67.330	1.00	68.29	C
ATOM	5522	CG2	ILE	B	313	41.978	14.999	64.721	1.00	68.84	C
ATOM	5526	C	ILE	B	313	42.954	12.445	65.390	1.00	68.99	C
ATOM	5527	O	ILE	B	313	44.139	12.741	65.273	1.00	69.34	O
ATOM	5529	N	ILE	B	314	42.360	11.548	64.613	1.00	67.46	N
ATOM	5530	CA	ILE	B	314	43.078	10.837	63.569	1.00	67.04	C
ATOM	5532	CB	ILE	B	314	42.600	9.337	63.471	1.00	67.19	C
ATOM	5534	CG1	ILE	B	314	43.132	8.495	64.633	1.00	67.44	C
ATOM	5537	CD1	ILE	B	314	42.847	9.003	65.998	1.00	67.98	C
ATOM	5541	CG2	ILE	B	314	43.120	8.637	62.198	1.00	66.89	C
ATOM	5545	C	ILE	B	314	42.795	11.572	62.283	1.00	66.44	C
ATOM	5546	O	ILE	B	314	41.642	11.656	61.898	1.00	66.69	O
ATOM	5548	N	THR	B	315	43.826	12.078	61.608	1.00	66.12	N
ATOM	5549	CA	THR	B	315	43.684	12.584	60.227	1.00	66.33	C
ATOM	5551	CB	THR	B	315	44.067	14.093	60.139	1.00	65.90	C
ATOM	5553	OG1	THR	B	315	45.466	14.232	60.300	1.00	67.05	O
ATOM	5555	CG2	THR	B	315	43.512	14.924	61.295	1.00	66.14	C
ATOM	5559	C	THR	B	315	44.516	11.764	59.200	1.00	66.52	C
ATOM	5560	O	THR	B	315	45.261	10.845	59.553	1.00	66.67	O
ATOM	5562	N	GLU	B	316	44.391	12.119	57.923	1.00	66.70	N
ATOM	5563	CA	GLU	B	316	45.316	11.623	56.887	1.00	66.85	C
ATOM	5565	CB	GLU	B	316	44.898	12.091	55.471	1.00	67.10	C
ATOM	5568	CG	GLU	B	316	44.974	13.593	55.192	1.00	67.03	C
ATOM	5571	CD	GLU	B	316	44.267	13.993	53.884	1.00	68.03	C
ATOM	5572	OE1	GLU	B	316	44.448	13.319	52.841	1.00	66.56	O
ATOM	5573	OE2	GLU	B	316	43.523	15.003	53.879	1.00	72.06	O
ATOM	5574	C	GLU	B	316	46.760	12.061	57.177	1.00	66.17	C
ATOM	5575	O	GLU	B	316	46.978	13.125	57.759	1.00	66.38	O
ATOM	5577	N	PHE	B	317	47.709	11.239	56.743	1.00	65.06	N
ATOM	5578	CA	PHE	B	317	49.127	11.482	56.905	1.00	64.62	C
ATOM	5580	CB	PHE	B	317	49.872	10.176	57.245	1.00	65.17	C
ATOM	5583	CG	PHE	B	317	51.356	10.356	57.383	1.00	66.01	C
ATOM	5584	CD1	PHE	B	317	51.876	11.177	58.388	1.00	67.15	C
ATOM	5586	CE1	PHE	B	317	53.259	11.380	58.497	1.00	67.42	C
ATOM	5588	CZ	PHE	B	317	54.125	10.773	57.587	1.00	67.18	C
ATOM	5590	CE2	PHE	B	317	53.610	9.963	56.573	1.00	66.79	C
ATOM	5592	CD2	PHE	B	317	52.234	9.775	56.466	1.00	66.42	C
ATOM	5594	C	PHE	B	317	49.673	12.074	55.608	1.00	63.60	C
ATOM	5595	O	PHE	B	317	49.302	11.640	54.523	1.00	63.73	O
ATOM	5597	N	MET	B	318	50.605	13.010	55.741	1.00	62.40	N
ATOM	5598	CA	MET	B	318	51.143	13.760	54.636	1.00	61.97	C
ATOM	5600	CB	MET	B	318	51.043	15.250	54.937	1.00	62.09	C
ATOM	5603	CG	MET	B	318	49.586	15.701	55.031	1.00	62.79	C
ATOM	5606	SD	MET	B	318	48.566	15.458	53.539	1.00	65.59	S
ATOM	5607	CE	MET	B	318	49.495	16.137	52.238	1.00	65.71	C
ATOM	5611	C	MET	B	318	52.576	13.309	54.380	1.00	61.63	C
ATOM	5612	O	MET	B	318	53.450	13.382	55.259	1.00	62.01	O
ATOM	5614	N	THR	B	319	52.800	12.860	53.144	1.00	60.85	N
ATOM	5615	CA	THR	B	319	53.886	11.929	52.803	1.00	59.80	C
ATOM	5617	CB	THR	B	319	53.416	11.105	51.607	1.00	59.64	C
ATOM	5619	OG1	THR	B	319	52.476	10.139	52.082	1.00	58.47	O
ATOM	5621	CG2	THR	B	319	54.476	10.241	51.024	1.00	61.13	C
ATOM	5625	C	THR	B	319	55.212	12.633	52.554	1.00	59.25	C
ATOM	5626	O	THR	B	319	56.258	12.011	52.679	1.00	59.56	O
ATOM	5628	N	TYR	B	320	55.150	13.929	52.232	1.00	58.42	N
ATOM	5629	CA	TYR	B	320	56.288	14.741	51.866	1.00	56.99	C
ATOM	5631	CB	TYR	B	320	56.071	15.244	50.428	1.00	57.33	C
ATOM	5634	CG	TYR	B	320	56.125	14.111	49.371	1.00	57.70	C
ATOM	5635	CD1	TYR	B	320	55.032	13.267	49.158	1.00	58.13	C
ATOM	5637	CE1	TYR	B	320	55.074	12.230	48.192	1.00	58.84	C
ATOM	5639	CZ	TYR	B	320	56.231	12.023	47.418	1.00	58.72	C
ATOM	5640	OH	TYR	B	320	56.268	10.955	46.480	1.00	57.02	O
ATOM	5642	CE2	TYR	B	320	57.330	12.878	47.608	1.00	57.30	C
ATOM	5644	CD2	TYR	B	320	57.276	13.899	48.577	1.00	57.97	C
ATOM	5646	C	TYR	B	320	56.585	15.883	52.881	1.00	56.79	C
ATOM	5647	O	TYR	B	320	57.490	16.690	52.630	1.00	57.93	O
ATOM	5649	N	GLY	B	321	55.894	15.950	54.027	1.00	55.52	N
ATOM	5650	CA	GLY	B	321	56.308	16.828	55.126	1.00	55.01	C
ATOM	5653	C	GLY	B	321	55.853	18.255	54.962	1.00	54.92	C
ATOM	5654	O	GLY	B	321	54.983	18.522	54.167	1.00	55.89	O
ATOM	5656	N	ASN	B	322	56.392	19.193	55.715	1.00	54.81	N
ATOM	5657	CA	ASN	B	322	55.813	20.531	55.676	1.00	55.82	C
ATOM	5659	CB	ASN	B	322	55.934	21.333	56.986	1.00	56.67	C
ATOM	5662	CG	ASN	B	322	57.322	21.772	57.250	1.00	59.45	C
ATOM	5663	OD1	ASN	B	322	58.230	20.945	57.291	1.00	60.95	O
ATOM	5664	ND2	ASN	B	322	57.515	23.073	57.444	1.00	64.38	N
ATOM	5667	C	ASN	B	322	56.409	21.290	54.573	1.00	55.03	C
ATOM	5668	O	ASN	B	322	57.461	20.940	54.090	1.00	55.55	O
ATOM	5670	N	LEU	B	323	55.737	22.375	54.238	1.00	54.09	N
ATOM	5671	CA	LEU	B	323	56.062	23.151	53.094	1.00	53.43	C
ATOM	5673	CB	LEU	B	323	54.852	24.022	52.759	1.00	53.53	C
ATOM	5676	CG	LEU	B	323	54.774	24.640	51.372	1.00	54.13	C
ATOM	5678	CD1	LEU	B	323	54.537	23.519	50.346	1.00	55.21	C
ATOM	5682	CD2	LEU	B	323	53.712	25.776	51.301	1.00	53.75	C
ATOM	5686	C	LEU	B	323	57.364	23.990	53.260	1.00	53.45	C
ATOM	5687	O	LEU	B	323	57.955	24.354	52.260	1.00	54.68	O
ATOM	5689	N	LEU	B	324	57.838	24.290	54.466	1.00	52.58	N
ATOM	5690	CA	LEU	B	324	59.178	24.900	54.606	1.00	52.25	C
ATOM	5692	CB	LEU	B	324	59.474	25.354	56.034	1.00	52.59	C
ATOM	5695	CG	LEU	B	324	58.666	26.544	56.508	1.00	53.69	C
ATOM	5697	CD1	LEU	B	324	59.289	27.008	57.822	1.00	53.57	C
ATOM	5701	CD2	LEU	B	324	58.671	27.696	55.448	1.00	54.16	C
ATOM	5705	C	LEU	B	324	60.324	24.014	54.212	1.00	50.92	C
ATOM	5706	O	LEU	B	324	61.124	24.372	53.366	1.00	50.69	O
ATOM	5708	N	ASP	B	325	60.403	22.865	54.844	1.00	49.78	N
ATOM	5709	CA	ASP	B	325	61.489	21.928	54.584	1.00	49.19	C
ATOM	5711	CB	ASP	B	325	61.417	20.724	55.515	1.00	49.24	C
ATOM	5714	CG	ASP	B	325	61.399	21.108	56.992	1.00	52.83	C
ATOM	5715	OD1	ASP	B	325	61.737	22.282	57.394	1.00	59.64	O
ATOM	5716	OD2	ASP	B	325	61.047	20.265	57.845	1.00	59.33	O
ATOM	5717	C	ASP	B	325	61.472	21.465	53.122	1.00	47.84	C
ATOM	5718	O	ASP	B	325	62.532	21.397	52.472	1.00	47.41	O
ATOM	5720	N	TYR	B	326	60.277	21.212	52.603	1.00	45.92	N
ATOM	5721	CA	TYR	B	326	60.129	20.872	51.208	1.00	45.83	C
ATOM	5723	CB	TYR	B	326	58.652	20.647	50.891	1.00	46.16	C
ATOM	5726	CG	TYR	B	326	58.355	20.096	49.526	1.00	45.58	C
ATOM	5727	CD1	TYR	B	326	58.442	18.737	49.281	1.00	46.52	C
ATOM	5729	CE1	TYR	B	326	58.129	18.213	48.019	1.00	46.47	C
ATOM	5731	CZ	TYR	B	326	57.722	19.076	46.997	1.00	45.99	C
ATOM	5732	OH	TYR	B	326	57.453	18.570	45.769	1.00	46.68	O
ATOM	5734	CE2	TYR	B	326	57.605	20.416	47.219	1.00	44.66	C
ATOM	5736	CD2	TYR	B	326	57.920	20.930	48.490	1.00	45.75	C
ATOM	5738	C	TYR	B	326	60.712	21.964	50.294	1.00	45.56	C
ATOM	5739	O	TYR	B	326	61.575	21.694	49.457	1.00	45.86	O
ATOM	5741	N	LEU	B	327	60.214	23.182	50.458	1.00	44.81	N
ATOM	5742	CA	LEU	B	327	60.671	24.294	49.695	1.00	44.18	C
ATOM	5744	CB	LEU	B	327	59.825	25.512	50.065	1.00	44.60	C
ATOM	5747	CG	LEU	B	327	58.433	25.703	49.440	1.00	44.78	C
ATOM	5749	CD1	LEU	B	327	57.741	26.874	50.137	1.00	45.05	C
ATOM	5753	CD2	LEU	B	327	58.490	25.999	47.889	1.00	43.39	C
ATOM	5757	C	LEU	B	327	62.201	24.597	49.873	1.00	44.18	C
ATOM	5758	O	LEU	B	327	62.865	24.960	48.915	1.00	43.53	O
ATOM	5760	N	ARG	B	328	62.722	24.462	51.097	1.00	44.12	N
ATOM	5761	CA	ARG	B	328	64.140	24.635	51.413	1.00	44.29	C
ATOM	5763	CB	ARG	B	328	64.356	24.590	52.918	1.00	44.11	C
ATOM	5766	CG	ARG	B	328	63.912	25.845	53.614	1.00	47.22	C
ATOM	5769	CD	ARG	B	328	63.732	25.780	55.147	1.00	47.72	C
ATOM	5772	NE	ARG	B	328	63.628	27.155	55.679	1.00	51.89	N
ATOM	5774	CZ	ARG	B	328	63.153	27.526	56.888	1.00	54.30	C
ATOM	5775	NH1	ARG	B	328	62.702	26.633	57.767	1.00	56.91	N
ATOM	5778	NH2	ARG	B	328	63.115	28.828	57.222	1.00	52.31	N
ATOM	5781	C	ARG	B	328	65.040	23.596	50.811	1.00	44.28	C
ATOM	5782	O	ARG	B	328	66.183	23.872	50.626	1.00	44.29	O
ATOM	5784	N	GLU	B	329	64.537	22.393	50.546	1.00	44.77	N
ATOM	5785	CA	GLU	B	329	65.337	21.253	50.088	1.00	45.63	C
ATOM	5787	CB	GLU	B	329	65.060	20.085	51.011	1.00	45.67	C
ATOM	5790	CG	GLU	B	329	65.517	20.396	52.413	1.00	48.46	C
ATOM	5793	CD	GLU	B	329	65.010	19.450	53.485	1.00	49.88	C
ATOM	5794	OE1	GLU	B	329	64.371	18.373	53.188	1.00	53.29	O
ATOM	5795	OE2	GLU	B	329	65.275	19.841	54.664	1.00	54.85	O
ATOM	5796	C	GLU	B	329	65.113	20.774	48.649	1.00	45.25	C
ATOM	5797	O	GLU	B	329	65.888	19.921	48.163	1.00	45.50	O
ATOM	5799	N	CYS	B	330	64.080	21.304	47.977	1.00	44.83	N
ATOM	5800	CA	CYS	B	330	63.706	20.921	46.607	1.00	44.55	C
ATOM	5802	CB	CYS	B	330	62.419	21.641	46.161	1.00	43.80	C
ATOM	5805	SG	CYS	B	330	62.531	23.462	46.036	1.00	46.00	S
ATOM	5807	C	CYS	B	330	64.848	21.192	45.601	1.00	43.89	C
ATOM	5808	O	CYS	B	330	65.846	21.878	45.933	1.00	44.55	O
ATOM	5810	N	ASN	B	331	64.721	20.577	44.416	1.00	42.32	N
ATOM	5811	CA	ASN	B	331	65.487	20.922	43.219	1.00	40.75	C
ATOM	5813	CB	ASN	B	331	65.657	19.689	42.328	1.00	39.93	C
ATOM	5816	CG	ASN	B	331	66.144	20.001	40.951	1.00	39.67	C
ATOM	5817	OD1	ASN	B	331	65.978	21.101	40.449	1.00	43.10	O
ATOM	5818	ND2	ASN	B	331	66.706	19.018	40.297	1.00	37.26	N
ATOM	5821	C	ASN	B	331	64.633	21.993	42.561	1.00	40.34	C
ATOM	5822	O	ASN	B	331	63.588	21.680	42.047	1.00	40.60	O
ATOM	5824	N	ARG	B	332	65.090	23.240	42.536	1.00	40.06	N
ATOM	5825	CA	ARG	B	332	64.279	24.347	41.983	1.00	39.76	C
ATOM	5827	CB	ARG	B	332	64.928	25.666	42.286	1.00	39.53	C
ATOM	5830	CG	ARG	B	332	64.934	26.006	43.725	1.00	39.04	C
ATOM	5833	CD	ARG	B	332	65.345	27.407	43.966	1.00	41.30	C
ATOM	5836	NE	ARG	B	332	65.672	27.656	45.356	1.00	43.82	N
ATOM	5838	CZ	ARG	B	332	65.843	28.878	45.889	1.00	47.86	C
ATOM	5839	NH1	ARG	B	332	65.742	30.022	45.172	1.00	47.83	N
ATOM	5842	NH2	ARG	B	332	66.159	28.966	47.172	1.00	49.85	N
ATOM	5845	C	ARG	B	332	63.972	24.290	40.483	1.00	40.24	C
ATOM	5846	O	ARG	B	332	63.041	24.939	40.018	1.00	40.19	O
ATOM	5848	N	GLN	B	333	64.733	23.503	39.724	1.00	41.33	N
ATOM	5849	CA	GLN	B	333	64.370	23.213	38.330	1.00	41.60	C
ATOM	5851	CB	GLN	B	333	65.489	22.565	37.522	1.00	40.28	C
ATOM	5854	CG	GLN	B	333	66.789	23.316	37.497	1.00	38.01	C
ATOM	5857	CD	GLN	B	333	66.645	24.810	37.158	1.00	37.58	C
ATOM	5858	OE1	GLN	B	333	66.093	25.151	36.116	1.00	35.75	O
ATOM	5859	NE2	GLN	B	333	67.171	25.695	38.029	1.00	35.24	N
ATOM	5862	C	GLN	B	333	63.105	22.376	38.286	1.00	42.51	C
ATOM	5863	O	GLN	B	333	62.363	22.545	37.327	1.00	43.43	O
ATOM	5865	N	GLU	B	334	62.842	21.555	39.325	1.00	43.09	N
ATOM	5866	CA	GLU	B	334	61.606	20.735	39.448	1.00	44.04	C
ATOM	5868	CB	GLU	B	334	61.828	19.470	40.279	1.00	44.33	C
ATOM	5871	CG	GLU	B	334	62.490	18.317	39.555	1.00	46.10	C
ATOM	5874	CD	GLU	B	334	62.823	17.154	40.514	1.00	48.08	C
ATOM	5875	OE1	GLU	B	334	62.444	17.225	41.719	1.00	55.37	O
ATOM	5876	OE2	GLU	B	334	63.442	16.147	40.080	1.00	50.14	O
ATOM	5877	C	GLU	B	334	60.440	21.485	40.078	1.00	43.28	C
ATOM	5878	O	GLU	B	334	59.386	21.585	39.471	1.00	44.76	O
ATOM	5880	N	VAL	B	335	60.610	21.957	41.298	1.00	42.40	N
ATOM	5881	CA	VAL	B	335	59.660	22.865	41.981	1.00	42.46	C
ATOM	5883	CB	VAL	B	335	59.798	22.721	43.549	1.00	42.61	C
ATOM	5885	CG1	VAL	B	335	58.921	23.659	44.308	1.00	42.12	C
ATOM	5889	CG2	VAL	B	335	59.534	21.219	43.992	1.00	43.74	C
ATOM	5893	C	VAL	B	335	59.942	24.319	41.437	1.00	42.51	C
ATOM	5894	O	VAL	B	335	60.405	25.248	42.120	1.00	41.41	O
ATOM	5896	N	ASN	B	336	59.612	24.459	40.166	1.00	42.36	N
ATOM	5897	CA	ASN	B	336	59.837	25.615	39.388	1.00	42.47	C
ATOM	5899	CB	ASN	B	336	59.970	25.155	37.927	1.00	44.16	C
ATOM	5902	CG	ASN	B	336	58.659	24.742	37.293	1.00	46.84	C
ATOM	5903	OD1	ASN	B	336	57.598	24.835	37.910	1.00	55.00	O
ATOM	5904	ND2	ASN	B	336	58.724	24.310	36.036	1.00	50.06	N
ATOM	5907	C	ASN	B	336	58.704	26.570	39.596	1.00	41.56	C
ATOM	5908	O	ASN	B	336	57.872	26.321	40.421	1.00	40.53	O
ATOM	5910	N	ALA	B	337	58.638	27.626	38.792	1.00	42.68	N
ATOM	5911	CA	ALA	B	337	57.631	28.727	38.966	1.00	42.87	C
ATOM	5913	CB	ALA	B	337	57.964	29.860	38.099	1.00	42.22	C
ATOM	5917	C	ALA	B	337	56.167	28.344	38.756	1.00	43.30	C
ATOM	5918	O	ALA	B	337	55.346	28.765	39.533	1.00	43.77	O
ATOM	5920	N	VAL	B	338	55.848	27.533	37.738	1.00	44.16	N
ATOM	5921	CA	VAL	B	338	54.505	26.912	37.614	1.00	44.19	C
ATOM	5923	CB	VAL	B	338	54.259	26.004	36.301	1.00	44.55	C
ATOM	5925	CG1	VAL	B	338	54.770	26.659	35.022	1.00	44.40	C
ATOM	5929	CG2	VAL	B	338	54.826	24.581	36.388	1.00	44.72	C
ATOM	5933	C	VAL	B	338	54.100	26.078	38.845	1.00	44.51	C
ATOM	5934	O	VAL	B	338	52.889	26.042	39.199	1.00	45.32	O
ATOM	5936	N	VAL	B	339	55.065	25.389	39.473	1.00	43.40	N
ATOM	5937	CA	VAL	B	339	54.722	24.623	40.691	1.00	43.21	C
ATOM	5939	CB	VAL	B	339	55.724	23.478	41.042	1.00	42.87	C
ATOM	5941	CG1	VAL	B	339	55.446	22.861	42.423	1.00	42.90	C
ATOM	5945	CG2	VAL	B	339	55.642	22.382	39.993	1.00	40.89	C
ATOM	5949	C	VAL	B	339	54.457	25.598	41.821	1.00	43.20	C
ATOM	5950	O	VAL	B	339	53.534	25.366	42.580	1.00	43.94	O
ATOM	5952	N	LEU	B	340	55.158	26.738	41.874	1.00	43.09	N
ATOM	5953	CA	LEU	B	340	54.842	27.770	42.888	1.00	42.40	C
ATOM	5955	CB	LEU	B	340	55.845	28.926	42.934	1.00	41.12	C
ATOM	5958	CG	LEU	B	340	57.322	28.614	43.315	1.00	39.97	C
ATOM	5960	CD1	LEU	B	340	58.098	29.797	43.795	1.00	38.85	C
ATOM	5964	CD2	LEU	B	340	57.498	27.526	44.373	1.00	42.87	C
ATOM	5968	C	LEU	B	340	53.406	28.209	42.740	1.00	43.14	C
ATOM	5969	O	LEU	B	340	52.626	28.062	43.675	1.00	44.25	O
ATOM	5971	N	LEU	B	341	53.017	28.593	41.539	1.00	44.01	N
ATOM	5972	CA	LEU	B	341	51.602	28.939	41.251	1.00	44.25	C
ATOM	5974	CB	LEU	B	341	51.427	29.244	39.772	1.00	44.45	C
ATOM	5977	CG	LEU	B	341	51.424	30.705	39.334	1.00	44.97	C
ATOM	5979	CD1	LEU	B	341	51.875	31.764	40.380	1.00	45.03	C
ATOM	5983	CD2	LEU	B	341	52.213	30.804	38.040	1.00	44.69	C
ATOM	5987	C	LEU	B	341	50.565	27.911	41.613	1.00	44.44	C
ATOM	5988	O	LEU	B	341	49.511	28.255	42.131	1.00	44.14	O
ATOM	5990	N	TYR	B	342	50.854	26.660	41.298	1.00	45.44	N
ATOM	5991	CA	TYR	B	342	49.938	25.570	41.607	1.00	46.41	C
ATOM	5993	CB	TYR	B	342	50.537	24.274	41.136	1.00	46.60	C
ATOM	5996	CG	TYR	B	342	49.769	23.017	41.450	1.00	46.39	C
ATOM	5997	CD1	TYR	B	342	48.386	22.919	41.265	1.00	46.14	C
ATOM	5999	CE1	TYR	B	342	47.700	21.707	41.523	1.00	46.60	C
ATOM	6001	CZ	TYR	B	342	48.425	20.600	41.977	1.00	49.02	C
ATOM	6002	OH	TYR	B	342	47.880	19.372	42.285	1.00	48.62	O
ATOM	6004	CE2	TYR	B	342	49.798	20.703	42.174	1.00	50.27	C
ATOM	6006	CD2	TYR	B	342	50.452	21.898	41.905	1.00	48.65	C
ATOM	6008	C	TYR	B	342	49.651	25.518	43.104	1.00	47.73	C
ATOM	6009	O	TYR	B	342	48.497	25.476	43.512	1.00	48.70	O
ATOM	6011	N	MET	B	343	50.711	25.573	43.904	1.00	48.51	N
ATOM	6012	CA	MET	B	343	50.605	25.521	45.352	1.00	49.05	C
ATOM	6014	CB	MET	B	343	51.991	25.524	46.003	1.00	49.15	C
ATOM	6017	CG	MET	B	343	52.855	24.302	45.668	1.00	50.17	C
ATOM	6020	SD	MET	B	343	54.574	24.212	46.372	1.00	52.32	S
ATOM	6021	CE	MET	B	343	54.747	25.849	47.112	1.00	52.41	C
ATOM	6025	C	MET	B	343	49.757	26.684	45.876	1.00	48.46	C
ATOM	6026	O	MET	B	343	48.854	26.447	46.683	1.00	48.89	O
ATOM	6028	N	ALA	B	344	49.986	27.908	45.391	1.00	47.96	N
ATOM	6029	CA	ALA	B	344	49.137	29.068	45.812	1.00	48.14	C
ATOM	6031	CB	ALA	B	344	49.692	30.374	45.307	1.00	47.60	C
ATOM	6035	C	ALA	B	344	47.647	28.936	45.416	1.00	47.93	C
ATOM	6036	O	ALA	B	344	46.763	29.323	46.171	1.00	46.98	O
ATOM	6038	N	THR	B	345	47.394	28.386	44.229	1.00	48.52	N
ATOM	6039	CA	THR	B	345	46.020	28.110	43.751	1.00	48.85	C
ATOM	6041	CB	THR	B	345	46.072	27.503	42.305	1.00	49.34	C
ATOM	6043	OG1	THR	B	345	46.775	28.402	41.425	1.00	50.75	O
ATOM	6045	CG2	THR	B	345	44.662	27.353	41.681	1.00	49.27	C
ATOM	6049	C	THR	B	345	45.299	27.147	44.682	1.00	48.53	C
ATOM	6050	O	THR	B	345	44.197	27.403	45.101	1.00	48.04	O
ATOM	6052	N	GLN	B	346	45.974	26.037	44.968	1.00	48.90	N
ATOM	6053	CA	GLN	B	346	45.546	25.016	45.902	1.00	48.82	C
ATOM	6055	CB	GLN	B	346	46.674	24.013	46.063	1.00	48.55	C
ATOM	6058	CG	GLN	B	346	46.773	23.068	44.929	1.00	49.36	C
ATOM	6061	CD	GLN	B	346	47.798	22.005	45.183	1.00	50.50	C
ATOM	6062	OE1	GLN	B	346	47.441	20.937	45.655	1.00	49.75	O
ATOM	6063	NE2	GLN	B	346	49.079	22.303	44.919	1.00	50.51	N
ATOM	6066	C	GLN	B	346	45.158	25.569	47.264	1.00	48.96	C
ATOM	6067	O	GLN	B	346	44.048	25.340	47.764	1.00	48.28	O
ATOM	6069	N	ILE	B	347	46.077	26.325	47.840	1.00	48.93	N
ATOM	6070	CA	ILE	B	347	45.830	26.931	49.139	1.00	49.62	C
ATOM	6072	CB	ILE	B	347	47.162	27.485	49.770	1.00	49.74	C
ATOM	6074	CG	ILE	B	347	48.200	26.360	49.961	1.00	50.81	C
ATOM	6077	CD1	ILE	B	347	49.677	26.934	50.135	1.00	51.35	C
ATOM	6081	CG2	ILE	B	347	46.926	28.232	51.120	1.00	48.40	C
ATOM	6085	C	ILE	B	347	44.723	28.029	49.076	1.00	49.56	C
ATOM	6086	O	ILE	B	347	43.999	28.147	50.049	1.00	50.95	O
ATOM	6088	N	SER	B	348	44.594	28.819	47.999	1.00	48.93	N
ATOM	6089	CA	SER	B	348	43.551	29.886	47.934	1.00	49.05	C
ATOM	6091	CB	SER	B	348	43.887	30.951	46.913	1.00	48.89	C
ATOM	6094	OG	SER	B	348	43.851	30.401	45.627	1.00	48.89	O
ATOM	6096	C	SER	B	348	42.145	29.347	47.632	1.00	49.20	C
ATOM	6097	O	SER	B	348	41.154	29.951	48.032	1.00	49.48	O
ATOM	6099	N	SER	B	349	42.074	28.242	46.890	1.00	49.19	N
ATOM	6100	CA	SER	B	349	40.882	27.372	46.803	1.00	49.07	C
ATOM	6102	CB	SER	B	349	41.258	26.118	45.992	1.00	49.03	C
ATOM	6105	OG	SER	B	349	40.277	25.100	45.988	1.00	49.12	O
ATOM	6107	C	SER	B	349	40.283	26.988	48.196	1.00	48.88	C
ATOM	6108	O	SER	B	349	39.081	27.181	48.446	1.00	48.10	O
ATOM	6110	N	ALA	B	350	41.140	26.468	49.072	1.00	48.93	N
ATOM	6111	CA	ALA	B	350	40.793	26.139	50.472	1.00	49.59	C
ATOM	6113	CB	ALA	B	350	41.998	25.554	51.173	1.00	49.82	C
ATOM	6117	C	ALA	B	350	40.272	27.304	51.317	1.00	50.55	C
ATOM	6118	O	ALA	B	350	39.359	27.153	52.084	1.00	50.92	O
ATOM	6120	N	MET	B	351	40.875	28.465	51.196	1.00	51.81	N
ATOM	6121	CA	MET	B	351	40.407	29.631	51.948	1.00	53.08	C
ATOM	6123	CB	MET	B	351	41.488	30.702	51.953	1.00	53.27	C
ATOM	6126	CG	MET	B	351	42.854	30.281	52.488	1.00	53.87	C
ATOM	6129	SD	MET	B	351	42.848	29.434	54.059	1.00	56.31	S
ATOM	6130	CE	MET	B	351	41.865	30.640	55.056	1.00	56.23	C
ATOM	6134	C	MET	B	351	39.088	30.222	51.435	1.00	53.48	C
ATOM	6135	O	MET	B	351	38.281	30.708	52.223	1.00	53.66	O
ATOM	6137	N	GLU	B	352	38.906	30.206	50.111	1.00	53.97	N
ATOM	6138	CA	GLU	B	352	37.602	30.514	49.439	1.00	53.40	C
ATOM	6140	CB	GLU	B	352	37.771	30.494	47.890	1.00	53.34	C
ATOM	6143	CG	GLU	B	352	36.566	30.105	47.048	1.00	54.31	C
ATOM	6146	CD	GLU	B	352	36.716	30.498	45.569	1.00	56.26	C
ATOM	6147	OE1	GLU	B	352	37.489	29.828	44.818	1.00	59.72	O
ATOM	6148	OE2	GLU	B	352	36.030	31.469	45.138	1.00	59.48	O
ATOM	6149	C	GLU	B	352	36.469	29.597	49.941	1.00	52.20	C
ATOM	6150	O	GLU	B	352	35.371	30.066	50.161	1.00	51.51	O
ATOM	6152	N	TYR	B	353	36.770	28.315	50.156	1.00	51.58	N
ATOM	6153	CA	TYR	B	353	35.809	27.337	50.729	1.00	51.45	C
ATOM	6155	CB	TYR	B	353	36.384	25.923	50.699	1.00	51.05	C
ATOM	6158	CG	TYR	B	353	35.607	24.901	51.471	1.00	51.39	C
ATOM	6159	CD1	TYR	B	353	34.509	24.255	50.895	1.00	51.40	C
ATOM	6161	CE1	TYR	B	353	33.768	23.290	51.592	1.00	50.75	C
ATOM	6163	CZ	TYR	B	353	34.129	22.941	52.873	1.00	51.95	C
ATOM	6164	OH	TYR	B	353	33.369	21.992	53.527	1.00	52.48	O
ATOM	6166	CE2	TYR	B	353	35.220	23.568	53.492	1.00	52.52	C
ATOM	6168	CD2	TYR	B	353	35.961	24.557	52.773	1.00	52.17	C
ATOM	6170	C	TYR	B	353	35.437	27.694	52.156	1.00	51.34	C
ATOM	6171	O	TYR	B	353	34.274	27.788	52.494	1.00	51.21	O
ATOM	6173	N	LEU	B	354	36.451	27.882	52.990	1.00	51.70	N
ATOM	6174	CA	LEU	B	354	36.257	28.360	54.360	1.00	51.19	C
ATOM	6176	CB	LEU	B	354	37.551	28.250	55.193	1.00	51.56	C
ATOM	6179	CG	LEU	B	354	38.239	26.878	55.370	1.00	51.86	C
ATOM	6181	CD1	LEU	B	354	39.385	27.006	56.340	1.00	51.42	C
ATOM	6185	CD2	LEU	B	354	37.307	25.780	55.855	1.00	53.30	C
ATOM	6189	C	LEU	B	354	35.698	29.771	54.429	1.00	50.03	C
ATOM	6190	O	LEU	B	354	35.057	30.068	55.402	1.00	49.16	O
ATOM	6192	N	GLU	B	355	35.897	30.600	53.411	1.00	49.71	N
ATOM	6193	CA	GLU	B	355	35.271	31.952	53.373	1.00	50.98	C
ATOM	6195	CB	GLU	B	355	35.909	32.823	52.275	1.00	50.57	C
ATOM	6198	CG	GLU	B	355	35.242	34.151	51.974	1.00	50.42	C
ATOM	6201	CD	GLU	B	355	36.038	34.989	50.948	1.00	52.55	C
ATOM	6202	OE1	GLU	B	355	35.944	34.744	49.697	1.00	52.19	O
ATOM	6203	OE2	GLU	B	355	36.759	35.920	51.400	1.00	54.21	O
ATOM	6204	C	GLU	B	355	33.743	31.823	53.191	1.00	51.27	C
ATOM	6205	O	GLU	B	355	32.951	32.272	54.019	1.00	50.91	O
ATOM	6207	N	LYS	B	356	33.367	31.153	52.114	1.00	52.39	N
ATOM	6208	CA	LYS	B	356	31.977	30.731	51.825	1.00	53.31	C
ATOM	6210	CB	LYS	B	356	31.986	29.672	50.687	1.00	52.80	C
ATOM	6213	CG	LYS	B	356	30.627	29.364	50.137	1.00	53.68	C
ATOM	6216	CD	LYS	B	356	30.670	28.890	48.684	1.00	55.06	C
ATOM	6219	CE	LYS	B	356	29.532	29.459	47.790	1.00	56.66	C
ATOM	6222	NZ	LYS	B	356	29.865	29.136	46.331	1.00	56.17	N
ATOM	6226	C	LYS	B	356	31.190	30.186	53.043	1.00	53.11	C
ATOM	6227	O	LYS	B	356	30.049	30.609	53.262	1.00	52.88	O
ATOM	6229	N	LYS	B	357	31.814	29.269	53.805	1.00	52.97	N
ATOM	6230	CA	LYS	B	357	31.265	28.740	55.068	1.00	53.04	C
ATOM	6232	CB	LYS	B	357	31.754	27.318	55.300	1.00	53.30	C
ATOM	6235	CG	LYS	B	357	31.395	26.364	54.178	1.00	53.20	C
ATOM	6238	CD	LYS	B	357	31.640	24.927	54.581	1.00	53.36	C
ATOM	6241	CE	LYS	B	357	30.365	24.066	54.751	1.00	55.93	C
ATOM	6244	NZ	LYS	B	357	30.544	22.695	54.049	1.00	56.88	N
ATOM	6248	C	LYS	B	357	31.533	29.566	56.335	1.00	53.17	C
ATOM	6249	O	LYS	B	357	31.205	29.120	57.439	1.00	52.57	O
ATOM	6251	N	ASN	B	358	32.102	30.770	56.165	1.00	53.61	N
ATOM	6252	CA	ASN	B	358	32.346	31.762	57.223	1.00	53.33	C
ATOM	6254	CB	ASN	B	358	30.996	32.319	57.722	1.00	53.57	C
ATOM	6257	CG	ASN	B	358	31.061	33.796	58.198	1.00	54.20	C
ATOM	6258	OD1	ASN	B	358	31.934	34.571	57.823	1.00	55.77	O
ATOM	6259	ND2	ASN	B	358	30.100	34.174	59.025	1.00	55.88	N
ATOM	6262	C	ASN	B	358	33.235	31.243	58.373	1.00	53.42	C
ATOM	6263	O	ASN	B	358	33.070	31.643	59.528	1.00	54.20	O
ATOM	6265	N	PHE	B	359	34.180	30.360	58.033	1.00	53.10	N
ATOM	6266	CA	PHE	B	359	35.257	29.919	58.931	1.00	52.82	C
ATOM	6268	CB	PHE	B	359	35.672	28.475	58.604	1.00	54.17	C
ATOM	6271	CG	PHE	B	359	34.776	27.459	59.203	1.00	55.27	C
ATOM	6272	CD1	PHE	B	359	35.010	26.992	60.490	1.00	58.03	C
ATOM	6274	CE1	PHE	B	359	34.145	26.029	61.088	1.00	58.89	C
ATOM	6276	CZ	PHE	B	359	33.018	25.528	60.384	1.00	57.33	C
ATOM	6278	CE2	PHE	B	359	32.776	25.992	59.078	1.00	58.10	C
ATOM	6280	CD2	PHE	B	359	33.662	26.984	58.502	1.00	58.68	C
ATOM	6282	C	PHE	B	359	36.494	30.827	58.866	1.00	51.31	C
ATOM	6283	O	PHE	B	359	36.817	31.361	57.814	1.00	50.90	O
ATOM	6285	N	ILE	B	360	37.175	30.989	60.000	1.00	50.15	N
ATOM	6286	CA	ILE	B	360	38.554	31.492	60.022	1.00	49.77	C
ATOM	6288	CB	ILE	B	360	38.667	32.846	60.724	1.00	49.77	C
ATOM	6290	CG1	ILE	B	360	38.110	32.814	62.147	1.00	49.19	C
ATOM	6293	CD1	ILE	B	360	38.574	34.039	62.973	1.00	49.80	C
ATOM	6297	CG2	ILE	B	360	37.968	33.933	59.880	1.00	50.05	C
ATOM	6301	C	ILE	B	360	39.536	30.427	60.580	1.00	49.72	C
ATOM	6302	O	ILE	B	360	39.151	29.571	61.365	1.00	49.63	O
ATOM	6304	N	HIS	B	361	40.780	30.469	60.097	1.00	49.57	N
ATOM	6305	CA	HIS	B	361	41.831	29.491	60.399	1.00	49.53	C
ATOM	6307	CB	HIS	B	361	42.713	29.247	59.156	1.00	49.65	C
ATOM	6310	CG	HIS	B	361	43.741	28.165	59.336	1.00	49.95	C
ATOM	6311	ND1	HIS	B	361	45.051	28.417	59.704	1.00	48.80	N
ATOM	6313	CE1	HIS	B	361	45.706	27.271	59.800	1.00	50.27	C
ATOM	6315	NE2	HIS	B	361	44.879	26.292	59.479	1.00	51.03	N
ATOM	6317	CD2	HIS	B	361	43.640	26.823	59.201	1.00	49.19	C
ATOM	6319	C	HIS	B	361	42.712	29.993	61.516	1.00	49.42	C
ATOM	6320	O	HIS	B	361	43.087	29.231	62.399	1.00	49.10	O
ATOM	6322	N	ARG	B	362	43.124	31.250	61.392	1.00	49.61	N
ATOM	6323	CA	ARG	B	362	43.966	31.971	62.352	1.00	50.28	C
ATOM	6325	CB	ARG	B	362	43.237	32.151	63.676	1.00	49.95	C
ATOM	6328	CG	ARG	B	362	42.136	33.185	63.627	1.00	50.78	C
ATOM	6331	CD	ARG	B	362	41.712	33.622	64.985	1.00	49.91	C
ATOM	6334	NE	ARG	B	362	41.403	32.439	65.765	1.00	48.95	N
ATOM	6336	CZ	ARG	B	362	41.544	32.320	67.073	1.00	51.46	C
ATOM	6337	NH1	ARG	B	362 41.959	33.343	67.845	1.00	51.57	N
ATOM	6340	NH2	ARG	B	362 41.204	31.155	67.652	1.00	53.04	N
ATOM	6343	C	ARG	B	362	45.423	31.551	62.600	1.00	50.31	C
ATOM	6344	O	ARG	B	362	46.092	32.245	63.322	1.00	50.08	O
ATOM	6346	N	ASP	B	363	45.922	30.460	62.027	1.00	51.58	N
ATOM	6347	CA	ASP	B	363	47.366	30.115	62.113	1.00	51.84	C
ATOM	6349	CB	ASP	B	363	47.617	29.114	63.244	1.00	52.50	C
ATOM	6352	CG	ASP	B	363	49.102	28.894	63.547	1.00	53.49	C
ATOM	6353	OD1	ASP	B	363 49.938	29.812	63.306	1.00	57.02	O
ATOM	6354	OD2	ASP	B	363	49.504	27.792	64.015	1.00	56.95	O
ATOM	6355	C	ASP	B	363	47.897	29.633	60.761	1.00	52.05	C
ATOM	6356	O	ASP	B	363	48.505	28.566	60.627	1.00	52.49	O
ATOM	6358	N	LEU	B	364	47.670	30.481	59.760	1.00	52.12	N
ATOM	6359	CA	LEU	B	364	48.019	30.201	58.365	1.00	51.31	C
ATOM	6361	CB	LEU	B	364	47.076	30.978	57.462	1.00	51.80	C
ATOM	6364	CG	LEU	B	364	47.074	30.765	55.958	1.00	52.67	C
ATOM	6366	CD1	LEU	B	364	46.666	29.353	55.618	1.00	53.11	C
ATOM	6370	CD2	LEU	B	364	46.135	31.827	55.295	1.00	52.29	C
ATOM	6374	C	LEU	B	364	49.444	30.664	58.179	1.00	49.67	C
ATOM	6375	O	LEU	B	364	49.782	31.761	58.531	1.00	51.46	O
ATOM	6377	N	ALA	B	365	50.256	29.818	57.607	1.00	47.82	N
ATOM	6378	CA	ALA	B	365	51.678	29.910	57.600	1.00	46.42	C
ATOM	6380	CB	ALA	B	365	52.218	29.956	59.018	1.00	46.55	C
ATOM	6384	C	ALA	B	365	52.179	28.635	56.894	1.00	46.17	C
ATOM	6385	O	ALA	B	365	51.540	27.601	56.905	1.00	45.40	O
ATOM	6387	N	ALA	B	366	53.338	28.741	56.295	1.00	46.80	N
ATOM	6388	CA	ALA	B	366	53.968	27.668	55.553	1.00	47.57	C
ATOM	6390	CB	ALA	B	366	55.289	28.178	54.995	1.00	48.13	C
ATOM	6394	C	ALA	B	366	54.210	26.412	56.390	1.00	47.64	C
ATOM	6395	O	ALA	B	366	53.971	25.321	55.923	1.00	46.90	O
ATOM	6397	N	ARG	B	367	54.630	26.594	57.644	1.00	48.44	N
ATOM	6398	CA	ARG	B	367	54.877	25.484	58.591	1.00	48.55	C
ATOM	6400	CB	ARG	B	367	55.465	25.985	59.918	1.00	47.93	C
ATOM	6403	CG	ARG	B	367	54.529	26.841	60.743	1.00	48.51	C
ATOM	6406	CD	ARG	B	367	55.139	27.555	61.948	1.00	49.87	C
ATOM	6409	NE	ARG	B	367	54.230	28.591	62.482	1.00	53.28	N
ATOM	6411	CZ	ARG	B	367	54.195	29.908	62.124	1.00	56.39	C
ATOM	6412	NH1	ARG	B	367	55.028	30.401	61.219	1.00	60.35	N
ATOM	6415	NH2	ARG	B	367	53.327	30.753	62.691	1.00	54.63	N
ATOM	6418	C	ARG	B	367	53.637	24.628	58.867	1.00	49.35	C
ATOM	6419	O	ARG	B	367	53.770	23.501	59.339	1.00	50.07	O
ATOM	6421	N	ASN	B	368	52.456	25.170	58.577	1.00	50.19	N
ATOM	6422	CA	ASN	B	368	51.185	24.477	58.690	1.00	50.81	C
ATOM	6424	CB	ASN	B	368	50.199	25.378	59.430	1.00	51.14	C
ATOM	6427	CG	ASN	B	368	50.632	25.657	60.800	1.00	50.73	C
ATOM	6428	OD1	ASN	B	368	51.332	24.859	61.397	1.00	51.15	O
ATOM	6429	ND2	ASN	B	368	50.247	26.803	61.320	1.00	52.40	N
ATOM	6432	C	ASN	B	368	50.574	24.057	57.376	1.00	51.32	C
ATOM	6433	O	ASN	B	368	49.427	23.572	57.371	1.00	51.72	O
ATOM	6435	N	CYS	B	369	51.291	24.253	56.271	1.00	51.29	N
ATOM	6436	CA	CYS	B	369	50.941	23.578	55.029	1.00	51.65	C
ATOM	6438	CB	CYS	B	369	51.193	24.467	53.868	1.00	51.65	C
ATOM	6441	SG	CYS	B	369	50.343	26.038	54.159	1.00	55.03	S
ATOM	6443	C	CYS	B	369	51.767	22.321	54.967	1.00	51.55	C
ATOM	6444	O	CYS	B	369	52.938	22.302	55.365	1.00	52.33	O
ATOM	6446	N	LEU	B	370	51.129	21.250	54.536	1.00	51.32	N
ATOM	6447	CA	LEU	B	370	51.765	19.950	54.394	1.00	51.06	C
ATOM	6449	CB	LEU	B	370	51.035	18.921	55.264	1.00	50.98	C
ATOM	6452	CG	LEU	B	370	51.435	18.640	56.729	1.00	49.93	C
ATOM	6454	CD1	LEU	B	370	52.580	19.493	57.203	1.00	50.05	C
ATOM	6458	CD2	LEU	B	370	50.261	18.733	57.695	1.00	48.45	C
ATOM	6462	C	LEU	B	370	51.717	19.555	52.947	1.00	50.86	C
ATOM	6463	O	LEU	B	370	50.873	20.029	52.230	1.00	50.99	O
ATOM	6465	N	VAL	B	371	52.619	18.680	52.530	1.00	51.51	N
ATOM	6466	CA	VAL	B	371	52.728	18.301	51.124	1.00	52.17	C
ATOM	6468	CB	VAL	B	371	54.115	18.636	50.523	1.00	52.20	C
ATOM	6470	CG1	VAL	B	371	54.047	18.603	48.967	1.00	50.93	C
ATOM	6474	CG2	VAL	B	371	54.611	20.017	51.023	1.00	51.52	C
ATOM	6478	C	VAL	B	371	52.414	16.831	50.916	1.00	52.80	C
ATOM	6479	O	VAL	B	371	52.650	15.996	51.789	1.00	53.35	O
ATOM	6481	N	GLY	B	372	51.847	16.543	49.751	1.00	53.47	N
ATOM	6482	CA	GLY	B	372	51.628	15.198	49.269	1.00	53.68	C
ATOM	6485	C	GLY	B	372	52.151	14.945	47.857	1.00	54.31	C
ATOM	6486	O	GLY	B	372	53.022	15.660	47.308	1.00	54.45	O
ATOM	6488	N	GLU	B	373	51.587	13.887	47.282	1.00	55.20	N
ATOM	6489	CA	GLU	B	373	52.038	13.267	46.036	1.00	54.98	C
ATOM	6491	CB	GLU	B	373	51.226	11.984	45.831	1.00	55.64	C
ATOM	6494	CG	GLU	B	373	51.939	10.896	45.093	1.00	60.09	C
ATOM	6497	CD	GLU	B	373	52.608	9.877	46.012	1.00	65.91	C
ATOM	6498	OE1	GLU	B	373	51.839	9.118	46.668	1.00	69.45	O
ATOM	6499	OE2	GLU	B	373	53.887	9.796	46.022	1.00	67.34	O
ATOM	6500	C	GLU	B	373	51.769	14.295	44.924	1.00	54.34	C
ATOM	6501	O	GLU	B	373	50.716	14.940	44.963	1.00	53.24	O
ATOM	6503	N	ASN	B	374	52.740	14.500	44.018	1.00	54.00	N
ATOM	6504	CA	ASN	B	374	52.634	15.459	42.861	1.00	53.84	C
ATOM	6506	CB	ASN	B	374	51.625	14.915	41.841	1.00	54.18	C
ATOM	6509	CG	ASN	B	374	51.793	15.505	40.413	1.00	54.64	C
ATOM	6510	OD1	ASN	B	374	52.830	16.110	40.050	1.00	52.89	O
ATOM	6511	ND2	ASN	B	374	50.752	15.282	39.583	1.00	54.67	N
ATOM	6514	C	ASN	B	374	52.285	16.935	43.213	1.00	53.43	C
ATOM	6515	O	ASN	B	374	51.356	17.542	42.657	1.00	53.15	O
ATOM	6517	N	HIS	B	375	53.026	17.471	44.178	1.00	53.02	N
ATOM	6518	CA	HIS	B	375	52.927	18.885	44.630	1.00	52.54	C
ATOM	6520	CB	HIS	B	375	53.354	19.854	43.499	1.00	52.15	C
ATOM	6523	CG	HIS	B	375	54.723	19.572	42.966	1.00	50.07	C
ATOM	6524	ND1	HIS	B	375	55.052	19.591	41.622	1.00	49.30	N
ATOM	6526	CE1	HIS	B	375	56.336	19.304	41.487	1.00	46.42	C
ATOM	6528	NE2	HIS	B	375	56.844	19.111	42.691	1.00	45.04	N
ATOM	6530	CD2	HIS	B	375	55.850	19.260	43.623	1.00	45.68	C
ATOM	6532	C	HIS	B	375	51.590	19.295	45.260	1.00	51.78	C
ATOM	6533	O	HIS	B	375	51.246	20.495	45.279	1.00	52.18	O
ATOM	6535	N	LEU	B	376	50.878	18.308	45.810	1.00	50.84	N
ATOM	6536	CA	LEU	B	376	49.586	18.537	46.471	1.00	50.31	C
ATOM	6538	CB	LEU	B	376	48.863	17.225	46.712	1.00	50.27	C
ATOM	6541	CG	LEU	B	376	47.485	17.292	47.362	1.00	50.31	C
ATOM	6543	CD1	LEU	B	376	46.401	17.526	46.278	1.00	52.32	C
ATOM	6547	CD2	LEU	B	376	47.229	16.042	48.150	1.00	47.19	C
ATOM	6551	C	LEU	B	376	49.865	19.188	47.811	1.00	49.98	C
ATOM	6552	O	LEU	B	376	50.608	18.609	48.605	1.00	49.49	O
ATOM	6554	N	VAL	B	377	49.297	20.382	48.048	1.00	49.71	N
ATOM	6555	CA	VAL	B	377	49.464	21.111	49.313	1.00	48.98	C
ATOM	6557	CB	VAL	B	377	49.951	22.505	49.065	1.00	48.72	C
ATOM	6559	CG1	VAL	B	377	50.284	23.171	50.389	1.00	49.65	C
ATOM	6563	CG2	VAL	B	377	51.186	22.473	48.230	1.00	49.10	C
ATOM	6567	C	VAL	B	377	48.121	21.139	50.057	1.00	49.03	C
ATOM	6568	O	VAL	B	377	47.067	21.367	49.430	1.00	49.97	O
ATOM	6570	N	LYS	B	378	48.139	20.909	51.368	1.00	48.50	N
ATOM	6571	CA	LYS	B	378	46.901	20.909	52.182	1.00	48.97	C
ATOM	6573	CB	LYS	B	378	46.442	19.477	52.544	1.00	49.43	C
ATOM	6576	CG	LYS	B	378	45.891	18.589	51.382	1.00	48.53	C
ATOM	6579	CD	LYS	B	378	45.476	17.235	51.865	1.00	48.74	C
ATOM	6582	CE	LYS	B	378	44.525	16.545	50.870	1.00	50.27	C
ATOM	6585	NZ	LYS	B	378	44.505	15.040	50.986	1.00	48.11	N
ATOM	6589	C	LYS	B	378	47.127	21.744	53.456	1.00	49.71	C
ATOM	6590	O	LYS	B	378	48.116	21.551	54.175	1.00	49.45	O
ATOM	6592	N	VAL	B	379	46.219	22.687	53.728	1.00	50.43	N
ATOM	6593	CA	VAL	B	379	46.322	23.521	54.918	1.00	50.48	C
ATOM	6595	CB	VAL	B	379	45.451	24.765	54.819	1.00	50.54	C
ATOM	6597	CG1	VAL	B	379	45.571	25.628	56.115	1.00	50.67	C
ATOM	6601	CG2	VAL	B	379	45.875	25.595	53.617	1.00	49.61	C
ATOM	6605	C	VAL	B	379	45.927	22.643	56.096	1.00	50.97	C
ATOM	6606	O	VAL	B	379	45.002	21.844	55.964	1.00	52.24	O
ATOM	6608	N	ALA	B	380	46.649	22.776	57.213	1.00	51.10	N
ATOM	6609	CA	ALA	B	380	46.445	21.979	58.428	1.00	51.04	C
ATOM	6611	CB	ALA	B	380	47.484	20.875	58.463	1.00	51.41	C
ATOM	6615	C	ALA	B	380	46.489	22.804	59.723	1.00	51.52	C
ATOM	6616	O	ALA	B	380	46.702	24.016	59.683	1.00	52.60	O
ATOM	6618	N	ASP	B	381	46.267	22.126	60.856	1.00	51.45	N
ATOM	6619	CA	ASP	B	381	46.149	22.705	62.208	1.00	50.86	C
ATOM	6621	CB	ASP	B	381	47.409	23.351	62.729	1.00	50.30	C
ATOM	6624	CG	ASP	B	381	47.380	23.487	64.223	1.00	51.47	C
ATOM	6625	OD1	ASP	B	381	46.285	23.684	64.799	1.00	54.38	O
ATOM	6626	OD2	ASP	B	381	48.382	23.345	64.942	1.00	53.95	O
ATOM	6627	C	ASP	B	381	44.995	23.652	62.386	1.00	51.12	C
ATOM	6628	O	ASP	B	381	45.120	24.881	62.225	1.00	51.58	O
ATOM	6630	N	PHE	B	382	43.892	23.077	62.828	1.00	51.55	N
ATOM	6631	CA	PHE	B	382	42.697	23.851	63.157	1.00	52.00	C
ATOM	6633	CB	PHE	B	382	41.475	23.145	62.538	1.00	52.71	C
ATOM	6636	CG	PHE	B	382	41.644	22.888	61.065	1.00	53.02	C
ATOM	6637	CD1	PHE	B	382	41.472	23.916	60.136	1.00	53.82	C
ATOM	6639	CE1	PHE	B	382	41.659	23.692	58.770	1.00	54.21	C
ATOM	6641	CZ	PHE	B	382	42.037	22.422	58.319	1.00	55.25	C
ATOM	6643	CE2	PHE	B	382	42.215	21.371	59.246	1.00	55.72	C
ATOM	6645	CD2	PHE	B	382	42.016	21.636	60.615	1.00	54.93	C
ATOM	6647	C	PHE	B	382	42.546	24.126	64.671	1.00	51.17	C
ATOM	6648	O	PHE	B	382	41.470	24.487	65.113	1.00	50.81	O
ATOM	6650	N	GLY	B	383	43.616	23.969	65.452	1.00	50.11	N
ATOM	6651	CA	GLY	B	383	43.568	24.290	66.852	1.00	50.07	C
ATOM	6654	C	GLY	B	383	42.989	25.674	67.182	1.00	50.37	C
ATOM	6655	O	GLY	B	383	42.260	25.794	68.162	1.00	50.65	O
ATOM	6657	N	LEU	B	384	43.308	26.689	66.365	1.00	50.10	N
ATOM	6658	CA	LEU	B	384	42.789	28.045	66.481	1.00	49.79	C
ATOM	6660	CB	LEU	B	384	43.962	29.027	66.313	1.00	49.37	C
ATOM	6663	CG	LEU	B	384	45.110	28.956	67.327	1.00	48.94	C
ATOM	6665	CD1	LEU	B	384	46.200	29.933	66.909	1.00	46.27	C
ATOM	6669	CD2	LEU	B	384	44.683	29.258	68.792	1.00	47.51	C
ATOM	6673	C	LEU	B	384	41.684	28.407	65.460	1.00	50.29	C
ATOM	6674	O	LEU	B	384	41.532	29.575	65.152	1.00	51.84	O
ATOM	6676	N	SER	B	385	40.914	27.459	64.931	1.00	50.11	N
ATOM	6677	CA	SER	B	385	39.796	27.771	64.000	1.00	50.06	C
ATOM	6679	CB	SER	B	385	39.511	26.576	63.121	1.00	50.19	C
ATOM	6682	OG	SER	B	385	40.484	26.549	62.112	1.00	52.84	O
ATOM	6684	C	SER	B	385	38.492	28.155	64.674	1.00	50.19	C
ATOM	6685	O	SER	B	385	38.322	27.893	65.823	1.00	50.01	O
ATOM	6687	N	ARG	B	386	37.565	28.751	63.935	1.00	50.70	N
ATOM	6688	CA	ARG	B	386	36.320	29.245	64.495	1.00	51.56	C
ATOM	6690	CB	ARG	B	386	36.490	30.653	65.102	1.00	52.33	C
ATOM	6693	CG	ARG	B	386	37.356	30.849	66.347	1.00	53.70	C
ATOM	6696	CD	ARG	B	386	36.924	30.111	67.622	1.00	56.86	C
ATOM	6699	NE	ARG	B	386	38.031	30.117	68.611	1.00	58.12	N
ATOM	6701	CZ	ARG	B	386	38.727	29.053	69.062	1.00	58.91	C
ATOM	6702	NH1	ARG	B	386	38.488	27.799	68.667	1.00	60.42	N
ATOM	6705	NH2	ARG	B	386	39.681	29.254	69.960	1.00	58.46	N
ATOM	6708	C	ARG	B	386	35.250	29.385	63.430	1.00	51.77	C
ATOM	6709	O	ARG	B	386	35.504	30.031	62.435	1.00	50.96	O
ATOM	6711	N	LEU	B	387	34.049	28.840	63.685	1.00	52.61	N
ATOM	6712	CA	LEU	B	387	32.814	29.222	62.940	1.00	52.85	C
ATOM	6714	CB	LEU	B	387	31.737	28.117	63.004	1.00	53.13	C
ATOM	6717	CG	LEU	B	387	30.313	28.476	62.473	1.00	53.38	C
ATOM	6719	CD1	LEU	B	387	29.917	27.755	61.206	1.00	53.46	C
ATOM	6723	CD2	LEU	B	387	29.265	28.208	63.541	1.00	55.37	C
ATOM	6727	C	LEU	B	387	32.215	30.545	63.461	1.00	52.49	C
ATOM	6728	O	LEU	B	387	31.588	30.577	64.502	1.00	52.24	O
ATOM	6730	N	MET	B	388	32.328	31.600	62.675	1.00	52.75	N
ATOM	6731	CA	MET	B	388	31.924	32.932	63.103	1.00	52.92	C
ATOM	6733	CB	MET	B	388	32.722	33.953	62.342	1.00	52.61	C
ATOM	6736	CG	MET	B	388	34.166	33.938	62.605	1.00	51.08	C
ATOM	6739	SD	MET	B	388	34.704	35.491	61.919	1.00	53.35	S
ATOM	6740	CE	MET	B	388	34.695	35.103	60.168	1.00	54.32	C
ATOM	6744	C	MET	B	388	30.462	33.298	62.858	1.00	53.68	C
ATOM	6745	O	MET	B	388	29.956	33.085	61.771	1.00	53.92	O
ATOM	6747	N	THR	B	389	29.825	33.873	63.882	1.00	54.77	N
ATOM	6748	CA	THR	B	389	28.690	34.787	63.746	1.00	55.77	C
ATOM	6750	CB	THR	B	389	27.921	34.924	65.088	1.00	55.87	C
ATOM	6752	OG1	THR	B	389	27.549	33.639	65.598	1.00	56.78	O
ATOM	6754	CG2	THR	B	389	26.577	35.630	64.905	1.00	56.50	C
ATOM	6758	C	THR	B	389	29.277	36.147	63.397	1.00	56.91	C
ATOM	6759	O	THR	B	389	30.169	36.636	64.104	1.00	57.57	O
ATOM	6761	N	GLY	B	390	28.798	36.769	62.321	1.00	58.00	N
ATOM	6762	CA	GLY	B	390	29.391	38.023	61.812	1.00	58.88	C
ATOM	6765	C	GLY	B	390	30.722	37.727	61.148	1.00	59.36	C
ATOM	6766	O	GLY	B	390	31.070	36.552	61.018	1.00	59.78	O
ATOM	6768	N	ASP	B	391	31.464	38.759	60.724	1.00	60.07	N
ATOM	6769	CA	ASP	B	391	32.888	38.567	60.320	1.00	60.19	C
ATOM	6771	CB	ASP	B	391	33.184	39.124	58.896	1.00	61.19	C
ATOM	6774	CG	ASP	B	391	34.574	38.627	58.296	1.00	61.68	C
ATOM	6775	OD1	ASP	B	391	34.740	37.375	58.117	1.00	62.75	O
ATOM	6776	OD2	ASP	B	391	35.521	39.433	57.957	1.00	61.66	O
ATOM	6777	C	ASP	B	391	33.831	39.157	61.353	1.00	59.13	C
ATOM	6778	O	ASP	B	391	34.836	39.765	61.005	1.00	60.25	O
ATOM	6780	N	THR	B	392	33.504	39.004	62.630	1.00	57.77	N
ATOM	6781	CA	THR	B	392	34.487	39.166	63.691	1.00	56.07	C
ATOM	6783	CB	THR	B	392	34.283	40.466	64.415	1.00	55.55	C
ATOM	6785	OG1	THR	B	392	34.437	41.524	63.475	1.00	54.07	O
ATOM	6787	CG2	THR	B	392	35.391	40.737	65.435	1.00	54.91	C
ATOM	6791	C	THR	B	392	34.437	37.958	64.623	1.00	55.94	C
ATOM	6792	O	THR	B	392	33.358	37.354	64.878	1.00	55.72	O
ATOM	6794	N	TYR	B	393	35.643	37.548	65.011	1.00	55.20	N
ATOM	6795	CA	TYR	B	393	35.894	36.786	66.218	1.00	54.75	C
ATOM	6797	CB	TYR	B	393	36.452	35.416	65.860	1.00	54.46	C
ATOM	6800	CG	TYR	B	393	36.644	34.571	67.068	1.00	54.65	C
ATOM	6801	CD1	TYR	B	393	35.581	33.863	67.614	1.00	53.91	C
ATOM	6803	CE1	TYR	B	393	35.748	33.090	68.769	1.00	55.30	C
ATOM	6805	CZ	TYR	B	393	36.996	33.055	69.405	1.00	55.84	C
ATOM	6806	OH	TYR	B	393	37.172	32.279	70.513	1.00	56.63	O
ATOM	6808	CE2	TYR	B	393	38.073	33.756	68.890	1.00	55.57	C
ATOM	6810	CD2	TYR	B	393	37.889	34.524	67.726	1.00	55.87	C
ATOM	6812	C	TYR	B	393	36.901	37.602	67.027	1.00	54.29	C
ATOM	6813	O	TYR	B	393	37.869	38.065	66.453	1.00	54.77	O
ATOM	6815	N	THR	B	394	36.686	37.792	68.332	1.00	54.39	N
ATOM	6816	CA	THR	B	394	37.691	38.462	69.188	1.00	54.91	C
ATOM	6818	CB	THR	B	394	37.208	39.849	69.686	1.00	54.76	C
ATOM	6820	OG1	THR	B	394	37.009	40.709	68.562	1.00	56.00	O
ATOM	6822	CG2	THR	B	394	38.295	40.629	70.406	1.00	54.43	C
ATOM	6826	C	THR	B	394	38.206	37.560	70.324	1.00	55.16	C
ATOM	6827	O	THR	B	394	37.426	37.024	71.117	1.00	55.43	O
ATOM	6829	N	ALA	B	395	39.535	37.437	70.378	1.00	55.30	N
ATOM	6830	CA	ALA	B	395	40.227	36.603	71.326	1.00	55.97	C
ATOM	6832	CB	ALA	B	395	41.565	36.166	70.749	1.00	56.01	C
ATOM	6836	C	ALA	B	395	40.466	37.359	72.597	1.00	57.10	C
ATOM	6837	O	ALA	B	395	40.604	38.590	72.571	1.00	57.98	O
ATOM	6839	N	HIS	B	396	40.555	36.622	73.705	1.00	57.90	N
ATOM	6840	CA	HIS	B	396	41.182	37.101	74.953	1.00	58.76	C
ATOM	6842	CB	HIS	B	396	41.481	35.912	75.896	1.00	59.30	C
ATOM	6845	CG	HIS	B	396	41.427	36.276	77.338	1.00	61.44	C
ATOM	6846	ND1	HIS	B	396	42.542	36.646	78.058	1.00	62.79	N
ATOM	6848	CE1	HIS	B	396	42.186	36.981	79.286	1.00	64.22	C
ATOM	6850	NE2	HIS	B	396	40.872	36.857	79.384	1.00	66.20	N
ATOM	6852	CD2	HIS	B	396	40.373	36.417	78.177	1.00	64.67	C
ATOM	6854	C	HIS	B	396	42.490	37.907	74.758	1.00	58.74	C
ATOM	6855	O	HIS	B	396	43.220	37.691	73.779	1.00	58.79	O
ATOM	6857	N	ALA	B	397	42.767	38.848	75.670	1.00	58.96	N
ATOM	6858	CA	ALA	B	397	44.137	39.420	75.810	1.00	58.93	C
ATOM	6860	CB	ALA	B	397	44.137	40.701	76.581	1.00	58.43	C
ATOM	6864	C	ALA	B	397	45.053	38.376	76.479	1.00	59.16	C
ATOM	6865	O	ALA	B	397	44.610	37.341	76.984	1.00	58.04	O
ATOM	6867	N	GLY	B	398	46.352	38.583	76.393	1.00	60.00	N
ATOM	6868	CA	GLY	B	398	47.292	37.534	76.813	1.00	60.70	C
ATOM	6871	C	GLY	B	398	47.303	36.267	75.966	1.00	60.73	C
ATOM	6872	O	GLY	B	398	48.161	35.418	76.176	1.00	60.77	O
ATOM	6874	N	ALA	B	399	46.328	36.105	75.060	1.00	60.88	N
ATOM	6875	CA	ALA	B	399	46.495	35.287	73.858	1.00	60.56	C
ATOM	6877	CB	ALA	B	399	45.196	35.173	73.074	1.00	60.48	C
ATOM	6881	C	ALA	B	399	47.528	35.999	73.026	1.00	59.93	C
ATOM	6882	O	ALA	B	399	47.247	37.080	72.529	1.00	60.40	O
ATOM	6884	N	LYS	B	400	48.727	35.415	72.942	1.00	59.18	N
ATOM	6885	CA	LYS	B	400	49.809	35.905	72.085	1.00	58.43	C
ATOM	6887	CB	LYS	B	400	51.172	35.723	72.780	1.00	59.26	C
ATOM	6890	CG	LYS	B	400	51.437	36.689	74.000	1.00	60.73	C
ATOM	6893	CD	LYS	B	400	51.132	38.147	73.671	1.00	61.59	C
ATOM	6896	CE	LYS	B	400	51.857	39.114	74.622	1.00	63.68	C
ATOM	6899	NZ	LYS	B	400	51.721	40.562	74.159	1.00	63.82	N
ATOM	6903	C	LYS	B	400	49.782	35.191	70.734	1.00	57.05	C
ATOM	6904	O	LYS	B	400	49.522	33.996	70.665	1.00	56.84	O
ATOM	6906	N	PHE	B	401	50.031	35.941	69.660	1.00	55.67	N
ATOM	6907	CA	PHE	B	401	50.090	35.403	68.308	1.00	54.70	C
ATOM	6909	CB	PHE	B	401	48.921	35.953	67.524	1.00	55.18	C
ATOM	6912	CG	PHE	B	401	47.620	35.512	68.066	1.00	55.72	C
ATOM	6913	CD1	PHE	B	401	47.185	34.172	67.850	1.00	57.74	C
ATOM	6915	CE1	PHE	B	401	45.937	33.698	68.383	1.00	57.37	C
ATOM	6917	CZ	PHE	B	401	45.134	34.587	69.173	1.00	57.21	C
ATOM	6919	CE2	PHE B	401	45.587	35.950	69.400	1.00	57.49	C
ATOM	6921	CD2	PHE	B	401	46.829	36.391	68.841	1.00	56.67	C
ATOM	6923	C	PHE	B	401	51.431	35.730	67.632	1.00	54.26	C
ATOM	6924	O	PHE	B	401	52.051	36.739	68.018	1.00	54.77	O
ATOM	6926	N	PRO	B	402	51.891	34.909	66.659	1.00	52.89	N
ATOM	6927	CA	PRO	B	402	53.141	35.165	65.939	1.00	52.59	C
ATOM	6929	CB	PRO	B	402	53.244	33.985	64.980	1.00	52.04	C
ATOM	6932	CG	PRO	B	402	51.915	33.574	64.804	1.00	52.25	C
ATOM	6935	CD	PRO	B	402	51.306	33.666	66.162	1.00	52.70	C
ATOM	6938	C	PRO	B	402	53.158	36.473	65.167	1.00	51.28	C
ATOM	6939	O	PRO	B	402	52.410	36.655	64.223	1.00	50.93	O
ATOM	6940	N	ILE	B	403	54.068	37.347	65.564	1.00	50.49	N
ATOM	6941	CA	ILE	B	403	54.118	38.711	65.066	1.00	49.71	C
ATOM	6943	CB	ILE	B	403	55.214	39.513	65.779	1.00	49.57	C
ATOM	6945	CG1	ILE	B	403	54.852	39.605	67.274	1.00	48.53	C
ATOM	6948	CD1	ILE	B	403	55.784	40.361	68.113	1.00	48.55	C
ATOM	6952	CG2	ILE	B	403	55.381	40.942	65.131	1.00	50.49	C
ATOM	6956	C	ILE	B	403	54.230	38.792	63.554	1.00	49.87	C
ATOM	6957	O	ILE	B	403	53.558	39.637	62.925	1.00	51.16	O
ATOM	6959	N	LYS	B	404	55.039	37.919	62.963	1.00	49.88	N
ATOM	6960	CA	LYS	B	404	55.349	38.027	61.518	1.00	49.82	C
ATOM	6962	CB	LYS	B	404	56.691	37.389	61.196	1.00	50.80	C
ATOM	6965	CG	LYS	B	404	57.835	38.174	61.804	1.00	53.31	C
ATOM	6968	CD	LYS	B	404	59.118	37.480	61.460	1.00	58.47	C
ATOM	6971	CE	LYS	B	404	60.368	38.173	62.014	1.00	58.71	C
ATOM	6974	NZ	LYS	B	404	61.326	37.028	62.268	1.00	63.21	N
ATOM	6978	C	LYS	B	404	54.256	37.540	60.584	1.00	47.84	C
ATOM	6979	O	LYS	B	404	54.318	37.752	59.415	1.00	47.75	O
ATOM	6981	N	TRP	B	405	53.258	36.895	61.114	1.00	46.55	N
ATOM	6982	CA	TRP	B	405	52.202	36.345	60.315	1.00	46.04	C
ATOM	6984	CB	TRP	B	405	52.140	34.829	60.550	1.00	45.86	C
ATOM	6987	CG	TRP	B	405	53.214	34.119	59.790	1.00	44.84	C
ATOM	6988	CD1	TRP	B	405	53.122	33.677	58.527	1.00	45.06	C
ATOM	6990	NE1	TRP	B	405	54.284	33.051	58.141	1.00	45.50	N
ATOM	6992	CE2	TRP	B	405	55.185	33.142	59.157	1.00	44.92	C
ATOM	6993	CD2	TRP	B	405	54.535	33.832	60.219	1.00	44.66	C
ATOM	6994	CE3	TRP	B	405	55.246	34.046	61.408	1.00	46.33	C
ATOM	6996	CZ3	TRP	B	405	56.603	33.566	61.487	1.00	45.72	C
ATOM	6998	CH2	TRP	B	405	57.203	32.901	60.398	1.00	43.78	C
ATOM	7000	CZ2	TRP	B	405	56.521	32.691	59.231	1.00	43.41	C
ATOM	7002	C	TRP	B	405	50.885	36.969	60.586	1.00	45.54	C
ATOM	7003	O	TRP	B	405	50.030	36.874	59.728	1.00	46.42	O
ATOM	7005	N	THR	B	406	50.726	37.619	61.740	1.00	45.08	N
ATOM	7006	CA	THR	B	406	49.462	38.119	62.190	1.00	44.69	C
ATOM	7008	CB	THR	B	406	49.469	38.239	63.669	1.00	44.33	C
ATOM	7010	OG1	THR	B	406	49.883	37.006	64.260	1.00	46.89	O
ATOM	7012	CG2	THR	B	406	48.074	38.480	64.206	1.00	44.14	C
ATOM	7016	C	THR	B	406	49.297	39.492	61.646	1.00	45.36	C
ATOM	7017	O	THR	B	406	50.269	40.294	61.610	1.00	46.48	O
ATOM	7019	N	ALA	B	407	48.038	39.821	61.347	1.00	45.45	N
ATOM	7020	CA	ALA	B	407	47.699	41.135	60.814	1.00	44.77	C
ATOM	7022	CB	ALA	B	407	46.327	41.129	60.222	1.00	44.93	C
ATOM	7026	C	ALA	B	407	47.770	42.114	61.939	1.00	44.66	C
ATOM	7027	O	ALA	B	407	47.586	41.691	63.045	1.00	44.40	O
ATOM	7029	N	PRO	B	408	48.028	43.404	61.658	1.00	45.22	N
ATOM	7030	CA	PRO	B	408	48.116	44.459	62.644	1.00	44.88	C
ATOM	7032	CB	PRO	B	408	48.069	45.723	61.779	1.00	44.93	C
ATOM	7035	CG	PRO	B	408	48.610	45.368	60.579	1.00	44.95	C
ATOM	7038	CD	PRO	B	408	48.293	43.958	60.327	1.00	45.57	C
ATOM	7041	C	PRO	B	408	46.998	44.512	63.659	1.00	45.59	C
ATOM	7042	O	PRO	B	408	47.247	44.430	64.864	1.00	45.08	O
ATOM	7043	N	GLU	B	409	45.771	44.635	63.170	1.00	46.70	N
ATOM	7044	CA	GLU	B	409	44.604	44.803	64.043	1.00	47.26	C
ATOM	7046	CB	GLU	B	409	43.363	45.231	63.255	1.00	46.76	C
ATOM	7049	CG	GLU	B	409	42.746	44.214	62.324	1.00	47.23	C
ATOM	7052	CD	GLU	B	409	43.528	43.953	61.050	1.00	50.93	C
ATOM	7053	OE1	GLU	B	409	44.494	44.705	60.771	1.00	54.85	O
ATOM	7054	OE2	GLU	B	409	43.193	42.970	60.336	1.00	51.60	O
ATOM	7055	C	GLU	B	409	44.359	43.532	64.896	1.00	48.10	C
ATOM	7056	O	GLU	B	409	43.832	43.628	66.033	1.00	47.56	O
ATOM	7058	N	SER	B	410	44.729	42.365	64.339	1.00	48.23	N
ATOM	7059	CA	SER	B	410	44.772	41.165	65.126	1.00	49.12	C
ATOM	7061	CB	SER	B	410	44.946	39.959	64.260	1.00	49.42	C
ATOM	7064	OG	SER	B	410	43.798	39.792	63.472	1.00	52.68	O
ATOM	7066	C	SER	B	410	45.849	41.215	66.202	1.00	49.38	C
ATOM	7067	O	SER	B	410	45.574	40.776	67.308	1.00	50.23	O
ATOM	7069	N	LEU	B	411	47.045	41.742	65.902	1.00	49.54	N
ATOM	7070	CA	LEU	B	411	48.091	42.022	66.943	1.00	49.72	C
ATOM	7072	CB	LEU	B	411	49.476	42.437	66.336	1.00	49.50	C
ATOM	7075	CG	LEU	B	411	50.296	41.378	65.561	1.00	51.21	C
ATOM	7077	CD1	LEU	B	411	51.634	41.935	65.153	1.00	51.19	C
ATOM	7081	CD2	LEU	B	411	50.523	40.053	66.360	1.00	52.38	C
ATOM	7085	C	LEU	B	411	47.679	43.078	67.992	1.00	49.70	C
ATOM	7086	O	LEU	B	411	48.017	42.935	69.152	1.00	49.53	O
ATOM	7088	N	ALA	B	412	46.966	44.117	67.571	1.00	49.85	N
ATOM	7089	CA	ALA	B	412	46.724	45.306	68.383	1.00	50.42	C
ATOM	7091	CB	ALA	B	412	46.709	46.573	67.487	1.00	49.98	C
ATOM	7095	C	ALA	B	412	45.431	45.222	69.209	1.00	51.15	C
ATOM	7096	O	ALA	B	412	45.399	45.719	70.328	1.00	52.64	O
ATOM	7098	N	TYR	B	413	44.374	44.622	68.662	1.00	51.39	N
ATOM	7099	CA	TYR	B	413	43.081	44.502	69.316	1.00	51.21	C
ATOM	7101	CB	TYR	B	413	42.055	45.369	68.581	1.00	52.01	C
ATOM	7104	CG	TYR	B	413	42.568	46.726	68.223	1.00	53.18	C
ATOM	7105	CD1	TYR	B	413	42.447	47.793	69.110	1.00	54.41	C
ATOM	7107	CE1	TYR	B	413	42.942	49.062	68.786	1.00	53.23	C
ATOM	7109	CZ	TYR	B	413	43.573	49.266	67.575	1.00	53.15	C
ATOM	7110	OH	TYR	B	413	44.061	50.514	67.270	1.00	54.57	O
ATOM	7112	CE2	TYR	B 413	43.719	48.219	66.676	1.00	54.14	C
ATOM	7114	CD2	TYR	B	413	43.209	46.953	67.001	1.00	53.77	C
ATOM	7116	C	TYR	B	413	42.560	43.063	69.370	1.00	51.19	C
ATOM	7117	O	TYR	B	413	41.400	42.883	69.706	1.00	51.03	O
ATOM	7119	N	ASN	B	414	43.365	42.045	69.043	1.00	51.30	N
ATOM	7120	CA	ASN	B	414	42.890	40.646	69.001	1.00	51.62	C
ATOM	7122	CB	ASN	B	414	42.772	40.090	70.441	1.00	52.08	C
ATOM	7125	CG	ASN	B	414	44.121	39.975	71.137	1.00	52.36	C
ATOM	7126	OD1	ASN	B	414	44.768	38.937	71.079	1.00	49.91	O
ATOM	7127	ND2	ASN	B	414	44.563	41.065	71.769	1.00	53.70	N
ATOM	7130	C	ASN	B	414	41.571	40.456	68.211	1.00	51.85	C
ATOM	7131	O	ASN	B	414	40.753	39.628	68.560	1.00	52.68	O
ATOM	7133	N	LYS	B	415	41.373	41.247	67.155	1.00	51.82	N
ATOM	7134	CA	LYS	B	415	40.178	41.186	66.287	1.00	51.60	C
ATOM	7136	CB	LYS	B	415	39.743	42.600	65.801	1.00	52.48	C
ATOM	7139	CG	LYS	B	415	38.839	43.413	66.764	1.00	53.82	C
ATOM	7142	CD	LYS	B	415	38.122	44.554	66.037	1.00	53.50	C
ATOM	7145	CE	LYS	B	415	37.629	45.612	67.050	1.00	56.22	C
ATOM	7148	NZ	LYS	B	415	37.256	46.951	66.440	1.00	56.46	N
ATOM	7152	C	LYS	B	415	40.565	40.368	65.075	1.00	49.64	C
ATOM	7153	O	LYS	B	415	41.317	40.844	64.231	1.00	49.81	O
ATOM	7155	N	PHE	B	416	40.056	39.156	64.987	1.00	47.61	N
ATOM	7156	CA	PHE	B	416	40.281	38.314	63.824	1.00	46.43	C
ATOM	7158	CB	PHE	B	416	40.632	36.907	64.272	1.00	45.58	C
ATOM	7161	CG	PHE	B	416	41.909	36.847	65.011	1.00	44.03	C
ATOM	7162	CD1	PHE	B	416	41.941	37.043	66.388	1.00	42.39	C
ATOM	7164	CE1	PHE	B	416	43.128	36.977	67.054	1.00	41.98	C
ATOM	7166	CZ	PHE	B	416	44.331	36.777	66.314	1.00	41.32	C
ATOM	7168	CE2	PHE	B	416	44.287	36.628	64.964	1.00	39.81	C
ATOM	7170	CD2	PHE	B	416	43.092	36.651	64.323	1.00	41.51	C
ATOM	7172	C	PHE	B	416	39.075	38.336	62.869	1.00	46.31	C
ATOM	7173	O	PHE	B	416	37.962	38.718	63.242	1.00	45.52	O
ATOM	7175	N	SER	B	417	39.340	37.972	61.620	1.00	46.14	N
ATOM	7176	CA	SER	B	417	38.333	38.003	60.577	1.00	46.57	C
ATOM	7178	CB	SER	B	417	38.034	39.480	60.174	1.00	46.06	C
ATOM	7181	OG	SER	B	417	38.993	40.002	59.267	1.00	45.60	O
ATOM	7183	C	SER	B	417	38.778	37.141	59.368	1.00	46.88	C
ATOM	7184	O	SER	B	417	39.834	36.551	59.367	1.00	47.28	O
ATOM	7186	N	ILE	B	418	37.964	37.077	58.335	1.00	47.08	N
ATOM	7187	CA	ILE	B	418	38.432	36.562	57.055	1.00	47.50	C
ATOM	7189	CB	ILE	B	418	37.235	36.318	56.105	1.00	46.99	C
ATOM	7191	CG	ILE	B	418	36.518	35.059	56.641	1.00	49.87	C
ATOM	7194	CD1	ILE	B	418	35.104	34.786	56.134	1.00	50.68	C
ATOM	7198	CG2	ILE	B	418	37.704	36.060	54.691	1.00	46.24	C
ATOM	7202	C	ILE	B	418	39.552	37.430	56.486	1.00	46.42	C
ATOM	7203	O	ILE	B	418	40.550	36.903	56.018	1.00	48.00	O
ATOM	7205	N	LYS	B	419	39.442	38.741	56.620	1.00	45.30	N
ATOM	7206	CA	LYS	B	419	40.518	39.632	56.178	1.00	44.18	C
ATOM	7208	CB	LYS	B	419	40.096	41.082	56.210	1.00	43.26	C
ATOM	7211	CG	LYS	B	419	38.797	41.379	55.479	1.00	43.63	C
ATOM	7214	CD	LYS	B	419	38.754	40.859	54.036	1.00	43.15	C
ATOM	7217	CE	LYS	B	419	37.933	41.751	53.104	1.00	41.60	C
ATOM	7220	NZ	LYS	B	419	38.179	41.398	51.699	1.00	39.80	N
ATOM	7224	C	LYS	B	419	41.813	39.447	56.972	1.00	43.94	C
ATOM	7225	O	LYS	B	419	42.877	39.653	56.415	1.00	43.27	O
ATOM	7227	N	SER	B	420	41.754	39.024	58.235	1.00	44.25	N
ATOM	7228	CA	SER	B	420	43.013	38.800	58.970	1.00	45.21	C
ATOM	7230	CB	SER	B	420	42.827	38.644	60.481	1.00	44.92	C
ATOM	7233	OG	SER	B	420	42.397	37.343	60.798	1.00	47.44	O
ATOM	7235	C	SER	B	420	43.757	37.624	58.330	1.00	45.51	C
ATOM	7236	O	SER	B	420	44.928	37.772	58.019	1.00	46.91	O
ATOM	7238	N	ASP	B	421	43.066	36.520	58.045	1.00	45.42	N
ATOM	7239	CA	ASP	B	421	43.659	35.395	57.297	1.00	45.45	C
ATOM	7241	CB	ASP	B	421	42.666	34.235	57.143	1.00	46.29	C
ATOM	7244	CG	ASP	B	421	42.386	33.503	58.463	1.00	49.26	C
ATOM	7245	OD1	ASP	B	421	42.682	34.047	59.592	1.00	53.74	O
ATOM	7246	OD2	ASP	B	421	41.798	32.398	58.445	1.00	49.93	O
ATOM	7247	C	ASP	B	421	44.181	35.753	55.913	1.00	44.47	C
ATOM	7248	O	ASP	B	421	45.185	35.198	55.478	1.00	45.25	O
ATOM	7250	N	VAL	B	422	43.513	36.649	55.209	1.00	42.85	N
ATOM	7251	CA	VAL	B	422	44.069	37.171	53.948	1.00	42.15	C
ATOM	7253	CB	VAL	B	422	42.993	38.103	53.269	1.00	42.62	C
ATOM	7255	CG1	VAL	B	422	43.566	39.073	52.223	1.00	43.05	C
ATOM	7259	CG2	VAL	B	422	41.884	37.257	52.682	1.00	41.64	C
ATOM	7263	C	VAL	B	422	45.511	37.823	54.122	1.00	41.82	C
ATOM	7264	O	VAL	B	422	46.427	37.657	53.260	1.00	41.08	O
ATOM	7266	N	TRP	B	423	45.719	38.520	55.239	1.00	40.82	N
ATOM	7267	CA	TRP	B	423	47.052	39.077	55.542	1.00	40.53	C
ATOM	7269	CB	TRP	B	423	47.053	39.849	56.846	1.00	39.80	C
ATOM	7272	CG	TRP	B	423	48.333	40.436	57.171	1.00	39.83	C
ATOM	7273	CD1	TRP	B	423	49.423	39.796	57.666	1.00	40.26	C
ATOM	7275	NE1	TRP	B	423	50.440	40.690	57.889	1.00	40.52	N
ATOM	7277	CE2	TRP	B	423	50.008	41.941	57.569	1.00	39.09	C
ATOM	7278	CD2	TRP	B	423	48.674	41.815	57.119	1.00	41.19	C
ATOM	7279	CE3	TRP	B	423	47.978	42.978	56.762	1.00	41.01	C
ATOM	7281	CZ3	TRP	B	423	48.656	44.231	56.820	1.00	40.90	C
ATOM	7283	CH2	TRP	B	423	49.996	44.310	57.244	1.00	40.22	C
ATOM	7285	CZ2	TRP	B	423	50.682	43.170	57.631	1.00	40.16	C
ATOM	7287	C	TRP	B	423	48.086	37.966	55.600	1.00	39.71	C
ATOM	7288	O	TRP	B	423	49.107	38.043	54.933	1.00	38.99	O
ATOM	7290	N	ALA	B	424	47.793	36.971	56.431	1.00	39.53	N
ATOM	7291	CA	ALA	B	424	48.636	35.802	56.644	1.00	39.67	C
ATOM	7293	CB	ALA	B	424	47.987	34.810	57.591	1.00	39.62	C
ATOM	7297	C	ALA	B	424	48.884	35.121	55.322	1.00	39.93	C
ATOM	7298	O	ALA	B	424	50.023	34.868	54.959	1.00	39.41	O
ATOM	7300	N	PHE	B	425	47.817	34.893	54.569	1.00	40.73	N
ATOM	7301	CA	PHE	B	425	47.956	34.337	53.246	1.00	41.46	C
ATOM	7303	CB	PHE	B	425	46.618	34.271	52.520	1.00	41.19	C
ATOM	7306	CG	PHE	B	425	46.756	33.764	51.148	1.00	42.09	C
ATOM	7307	CD1	PHE	B	425	46.779	32.342	50.915	1.00	41.45	C
ATOM	7309	CE1	PHE	B	425	46.987	31.816	49.655	1.00	38.78	C
ATOM	7311	CZ	PHE	B	425	47.195	32.712	48.583	1.00	40.92	C
ATOM	7313	CE2	PHE	B	425	47.229	34.167	48.814	1.00	41.74	C
ATOM	7315	CD2	PHE	B	425	47.012	34.670	50.092	1.00	39.72	C
ATOM	7317	C	PHE	B	425	49.006	35.123	52.451	1.00	41.98	C
ATOM	7318	O	PHE	B	425	49.854	34.516	51.846	1.00	42.33	O
ATOM	7320	N	GLY	B	426	48.955	36.469	52.503	1.00	43.52	N
ATOM	7321	CA	GLY	B	426	50.014	37.371	51.959	1.00	42.94	C
ATOM	7324	C	GLY	B	426	51.440	36.975	52.290	1.00	43.22	C
ATOM	7325	O	GLY	B	426	52.302	36.952	51.416	1.00	43.25	O
ATOM	7327	N	VAL	B	427	51.660	36.623	53.554	1.00	43.45	N
ATOM	7328	CA	VAL	B	427	52.980	36.205	54.077	1.00	43.77	C
ATOM	7330	CB	VAL	B	427	53.063	36.327	55.624	1.00	43.99	C
ATOM	7332	CG1	VAL	B	427	54.468	35.973	56.147	1.00	45.40	C
ATOM	7336	CG2	VAL	B	427	52.687	37.756	56.071	1.00	44.09	C
ATOM	7340	C	VAL	B	427	53.298	34.771	53.670	1.00	43.37	C
ATOM	7341	O	VAL	B	427	54.451	34.429	53.416	1.00	43.04	O
ATOM	7343	N	LEU	B	428	52.278	33.942	53.600	1.00	43.10	N
ATOM	7344	CA	LEU	B	428	52.428	32.630	53.060	1.00	43.80	C
ATOM	7346	CB	LEU	B	428	51.119	31.860	53.084	1.00	43.17	C
ATOM	7349	CG	LEU	B	428	51.174	30.429	52.564	1.00	45.01	C
ATOM	7351	CD1	LEU	B	428	52.486	29.666	52.813	1.00	46.52	C
ATOM	7355	CD2	LEU	B	428	50.029	29.630	53.231	1.00	45.52	C
ATOM	7359	C	LEU	B	428	52.962	32.708	51.642	1.00	44.29	C
ATOM	7360	O	LEU	B	428	53.845	31.915	51.263	1.00	45.65	O
ATOM	7362	N	LEU	B	429	52.469	33.663	50.862	1.00	43.82	N
ATOM	7363	CA	LEU	B	429	52.914	33.770	49.485	1.00	43.60	C
ATOM	7365	CB	LEU	B	429	52.122	34.824	48.722	1.00	43.53	C
ATOM	7368	CG	LEU	B	429	50.752	34.486	48.209	1.00	42.53	C
ATOM	7370	CD1	LEU	B	429	50.241	35.683	47.456	1.00	43.70	C
ATOM	7374	CD2	LEU	B	429	50.817	33.249	47.285	1.00	42.23	C
ATOM	7378	C	LEU	B	429	54.376	34.135	49.422	1.00	44.23	C
ATOM	7379	O	LEU	B	429	55.088	33.695	48.492	1.00	44.56	O
ATOM	7381	N	TRP	B	430	54.790	34.963	50.392	1.00	44.50	N
ATOM	7382	CA	TRP	B	430	56.149	35.466	50.486	1.00	44.13	C
ATOM	7384	CB	TRP	B	430	56.278	36.578	51.556	1.00	45.43	C
ATOM	7387	CG	TRP	B	430	57.602	37.287	51.497	1.00	45.49	C
ATOM	7388	CD1	TRP	B	430	57.918	38.322	50.703	1.00	46.10	C
ATOM	7390	NE1	TRP	B	430	59.233	38.684	50.878	1.00	46.68	N
ATOM	7392	CE2	TRP	B	430	59.805	37.841	51.787	1.00	45.24	C
ATOM	7393	CD2	TRP	B	430	58.795	36.939	52.206	1.00	45.96	C
ATOM	7394	CE3	TRP	B	430	59.116	35.952	53.166	1.00	46.57	C
ATOM	7396	CZ3	TRP	B	430	60.409	35.916	53.675	1.00	46.75	C
ATOM	7398	CH2	TRP	B	430	61.401	36.864	53.230	1.00	46.23	C
ATOM	7400	CZ2	TRP	B	430	61.105	37.823	52.298	1.00	45.00	C
ATOM	7402	C	TRP	B	430	57.072	34.358	50.804	1.00	42.97	C
ATOM	7403	O	TRP	B	430	58.144	34.331	50.280	1.00	41.66	O
ATOM	7405	N	GLU	B	431	56.647	33.443	51.662	1.00	43.57	N
ATOM	7406	CA	GLU	B	431	57.500	32.285	52.048	1.00	44.58	C
ATOM	7408	CB	GLU	B	431	56.921	31.499	53.217	1.00	43.57	C
ATOM	7411	CG	GLU	B	431	56.872	32.230	54.558	1.00	45.47	C
ATOM	7414	CD	GLU	B	431	56.223	31.363	55.657	1.00	48.63	C
ATOM	7415	OE1	GLU	B	431	54.937	31.250	55.709	1.00	50.27	O
ATOM	7416	OE2	GLU	B	431	57.023	30.744	56.443	1.00	54.96	O
ATOM	7417	C	GLU	B	431	57.667	31.347	50.884	1.00	44.43	C
ATOM	7418	O	GLU	B	431	58.723	30.745	50.727	1.00	45.17	O
ATOM	7420	N	ILE	B	432	56.613	31.213	50.076	1.00	44.85	N
ATOM	7421	CA	ILE	B	432	56.627	30.325	48.900	1.00	44.73	C
ATOM	7423	CB	ILE	B	432	55.170	30.162	48.341	1.00	44.71	C
ATOM	7425	CG1	ILE	B	432	54.386	29.291	49.294	1.00	44.20	C
ATOM	7428	CD1	ILE	B	432	52.932	29.328	49.080	1.00	46.03	C
ATOM	7432	CG2	ILE	B	432	55.139	29.575	46.912	1.00	44.97	C
ATOM	7436	C	ILE	B	432	57.638	30.917	47.877	1.00	44.53	C
ATOM	7437	O	ILE	B	432	58.600	30.193	47.437	1.00	44.41	O
ATOM	7439	N	ALA	B	433	57.432	32.208	47.567	1.00	42.33	N
ATOM	7440	CA	ALA	B	433	58.303	32.959	46.700	1.00	42.53	C
ATOM	7442	CB	ALA	B	433	57.874	34.460	46.671	1.00	43.90	C
ATOM	7446	C	ALA	B	433	59.797	32.889	47.022	1.00	42.39	C
ATOM	7447	O	ALA	B	433	60.628	32.843	46.112	1.00	44.01	O
ATOM	7449	N	THR	B	434	60.150	32.904	48.292	1.00	41.40	N
ATOM	7450	CA	THR	B	434	61.538	32.810	48.692	1.00	40.51	C
ATOM	7452	CB	THR	B	434	61.744	33.673	49.936	1.00	39.64	C
ATOM	7454	OG1	THR	B	434	60.861	33.275	50.996	1.00	38.03	O
ATOM	7456	CG2	THR	B	434	61.323	35.111	49.673	1.00	39.97	C
ATOM	7460	C	THR	B	434	61.968	31.349	48.959	1.00	41.24	C
ATOM	7461	O	THR	B	434	62.990	31.152	49.586	1.00	41.64	O
ATOM	7463	N	TYR	B	435	61.209	30.320	48.547	1.00	41.60	N
ATOM	7464	CA	TYR	B	435	61.531	28.902	48.933	1.00	41.87	C
ATOM	7466	CB	TYR	B	435	62.670	28.341	48.072	1.00	40.58	C
ATOM	7469	CG	TYR	B	435	62.278	28.202	46.638	1.00	39.86	C
ATOM	7470	CD1	TYR	B	435	62.362	29.303	45.747	1.00	38.77	C
ATOM	7472	CE1	TYR	B	435	61.971	29.189	44.422	1.00	37.75	C
ATOM	7474	CZ	TYR	B	435	61.502	27.938	43.967	1.00	39.39	C
ATOM	7475	OH	TYR	B	435	61.126	27.771	42.670	1.00	39.34	O
ATOM	7477	CE2	TYR	B	435	61.410	26.839	44.829	1.00	37.30	C
ATOM	7479	CD2	TYR	B	435	61.780	26.981	46.155	1.00	37.41	C
ATOM	7481	C	TYR	B	435	61.842	28.732	50.438	1.00	43.41	C
ATOM	7482	O	TYR	B	435	62.779	27.989	50.849	1.00	43.02	O
ATOM	7484	N	GLY	B	436	61.067	29.472	51.239	1.00	44.71	N
ATOM	7485	CA	GLY	B	436	61.017	29.303	52.684	1.00	46.27	C
ATOM	7488	C	GLY	B	436	61.947	30.147	53.533	1.00	47.33	C
ATOM	7489	O	GLY	B	436	62.348	29.748	54.636	1.00	48.29	O
ATOM	7491	N	MET	B	437	62.285	31.331	53.071	1.00	48.59	N
ATOM	7492	CA	MET	B	437	62.949	32.247	53.967	1.00	49.82	C
ATOM	7494	CB	MET	B	437	63.387	33.490	53.264	1.00	49.54	C
ATOM	7497	CG	MET	B	437	64.617	33.284	52.389	1.00	52.30	C
ATOM	7500	SD	MET	B	437	65.234	34.919	51.796	1.00	55.51	S
ATOM	7501	CE	MET	B	437	65.384	35.857	53.375	1.00	58.82	C
ATOM	7505	C	MET	B	437	62.029	32.627	55.103	1.00	48.51	C
ATOM	7506	O	MET	B	437	60.857	32.759	54.919	1.00	49.50	O
ATOM	7508	N	SER	B	438	62.603	32.790	56.279	1.00	48.19	N
ATOM	7509	CA	SER	B	438	61.949	33.390	57.432	1.00	47.57	C
ATOM	7511	CB	SER	B	438	62.906	33.253	58.609	1.00	47.24	C
ATOM	7514	OG	SER	B	438	62.259	33.689	59.777	1.00	52.44	O
ATOM	7516	C	SER	B	438	61.598	34.907	57.174	1.00	46.76	C
ATOM	7517	O	SER	B	438	62.484	35.664	56.763	1.00	46.75	O
ATOM	7519	N	PRO	B	439	60.343	35.333	57.326	1.00	45.74	N
ATOM	7520	CA	PRO	B	439	59.949	36.745	57.049	1.00	45.91	C
ATOM	7522	CB	PRO	B	439	58.420	36.797	57.333	1.00	45.79	C
ATOM	7525	CG	PRO	B	439	58.012	35.479	57.802	1.00	46.45	C
ATOM	7528	CD	PRO	B	439	59.186	34.501	57.681	1.00	46.24	C
ATOM	7531	C	PRO	B	439	60.682	37.859	57.831	1.00	45.00	C
ATOM	7532	O	PRO	B	439	61.295	37.614	58.875	1.00	45.64	O
ATOM	7533	N	TYR	B	440	60.634	39.056	57.274	1.00	43.58	N
ATOM	7534	CA	TYR	B	440	61.341	40.215	57.787	1.00	43.59	C
ATOM	7536	CB	TYR	B	440	60.533	40.869	58.897	1.00	43.85	C
ATOM	7539	CG	TYR	B	440	59.109	41.156	58.513	1.00	45.19	C
ATOM	7540	CD1	TYR	B	440	58.745	42.332	57.850	1.00	48.24	C
ATOM	7542	CE1	TYR	B	440	57.416	42.572	57.496	1.00	46.93	C
ATOM	7544	CZ	TYR	B	440	56.464	41.632	57.826	1.00	45.57	C
ATOM	7545	OH	TYR	B	440	55.138	41.789	57.542	1.00	47.40	O
ATOM	7547	CE2	TYR	B	440	56.803	40.509	58.484	1.00	47.26	C
ATOM	7549	CD2	TYR	B	440	58.117	40.264	58.808	1.00	47.98	C
ATOM	7551	C	TYR	B	440	62.753	39.898	58.249	1.00	42.40	C
ATOM	7552	O	TYR	B	440	63.159	40.328	59.316	1.00	41.59	O
ATOM	7554	N	PRO	B	441	63.507	39.155	57.439	1.00	41.60	N
ATOM	7555	CA	PRO	B	441	64.761	38.512	57.925	1.00	41.97	C
ATOM	7557	CB	PRO	B	441	65.323	37.833	56.678	1.00	41.25	C
ATOM	7560	CG	PRO	B	441	64.672	38.557	55.539	1.00	41.33	C
ATOM	7563	CD	PRO	B	441	63.302	38.941	55.997	1.00	41.06	C
ATOM	7566	C	PRO	B	441	65.692	39.594	58.449	1.00	42.48	C
ATOM	7567	O	PRO	B	441	65.757	40.689	57.825	1.00	44.88	O
ATOM	7568	N	GLY	B	442	66.284	39.377	59.620	1.00	42.00	N
ATOM	7569	CA	GLY	B	442	67.190	40.354	60.207	1.00	42.52	C
ATOM	7572	C	GLY	B	442	66.545	41.421	61.066	1.00	42.98	C
ATOM	7573	O	GLY	B	442	67.246	42.073	61.816	1.00	43.85	O
ATOM	7575	N	ILE	B	443	65.223	41.583	60.991	1.00	43.59	N
ATOM	7576	CA	ILE	B	443	64.467	42.596	61.729	1.00	43.65	C
ATOM	7578	CB	ILE	B	443	63.274	43.076	60.912	1.00	43.19	C
ATOM	7580	CG1	LE	B	443	63.781	43.664	59.594	1.00	44.00	C
ATOM	7583	CD1	ILE	B	443	62.727	43.878	58.504	1.00	45.01	C
ATOM	7587	CG2	ILE	B	443	62.455	44.126	61.687	1.00	43.94	C
ATOM	7591	C	ILE	B	443	63.977	41.980	63.042	1.00	44.13	C
ATOM	7592	O	ILE	B	443	63.406	40.930	63.021	1.00	44.69	O
ATOM	7594	N	ASP	B	444	64.176	42.678	64.165	1.00	45.09	N
ATOM	7595	CA	ASP	B	444	63.785	42.217	65.479	1.00	45.27	C
ATOM	7597	CB	ASP	B	444	64.455	43.059	66.580	1.00	46.01	C
ATOM	7600	CG	ASP	B	444	64.394	42.383	67.976	1.00	50.38	C
ATOM	7601	OD1	ASP	B	444	65.232	41.480	68.279	1.00	54.48	O
ATOM	7602	OD2	ASP	B	444	63.532	42.693	68.846	1.00	56.55	O
ATOM	7603	C	ASP	B	444	62.252	42.284	65.609	1.00	45.10	C
ATOM	7604	O	ASP	B	444	61.603	43.248	65.149	1.00	45.64	O
ATOM	7606	N	LEU	B	445	61.691	41.263	66.265	1.00	44.14	N
ATOM	7607	CA	LEU	B	445	60.263	41.178	66.522	1.00	43.02	C
ATOM	7609	CB	LEU	B	445	59.897	39.974	67.410	1.00	42.94	C
ATOM	7612	CG	LEU	B	445	60.355	38.578	67.000	1.00	39.91	C
ATOM	7614	CD1	LEU	B	445	59.679	37.598	67.838	1.00	39.50	C
ATOM	7618	CD2	LEU	B	445	60.056	38.313	65.593	1.00	39.23	C
ATOM	7622	C	LEU	B	445	59.739	42.397	67.185	1.00	42.88	C
ATOM	7623	O	LEU	B	445	58.654	42.778	66.854	1.00	43.96	O
ATOM	7625	N	SER	B	446	60.510	43.031	68.076	1.00	42.48	N
ATOM	7626	CA	SER	B	446	60.078	44.261	68.708	1.00	43.16	C
ATOM	7628	CB	SER	B	446	61.125	44.808	69.675	1.00	43.32	C
ATOM	7631	OG	SER	B	446	62.318	45.279	69.026	1.00	46.55	O
ATOM	7633	C	SER	B	446	59.696	45.358	67.734	1.00	43.33	C
ATOM	7634	O	SER	B	446	58.947	46.232	68.121	1.00	43.82	O
ATOM	7636	N	GLN	B	447	60.201	45.311	66.490	1.00	43.85	N
ATOM	7637	CA	GLN	B	447	60.074	46.422	65.502	1.00	43.96	C
ATOM	7639	CB	GLN	B	447	61.444	46.701	64.829	1.00	44.59	C
ATOM	7642	CG	GLN	B	447	62.549	47.135	65.804	1.00	44.79	C
ATOM	7645	CD	GLN	B	447	62.113	48.281	66.696	1.00	46.24	C
ATOM	7646	OE1	GLN	B	447	62.196	49.447	66.282	1.00	50.99	O
ATOM	7647	NE2	GLN	B	447	61.599	47.959	67.897	1.00	41.42	N
ATOM	7650	C	GLN	B	447	59.020	46.256	64.446	1.00	43.16	C
ATOM	7651	O	GLN	B	447	58.540	47.242	63.898	1.00	42.27	O
ATOM	7653	N	VAL	B	448	58.601	45.015	64.256	1.00	43.37	N
ATOM	7654	CA	VAL	B	448	57.756	44.597	63.149	1.00	43.31	C
ATOM	7656	CB	VAL	B	448	57.659	43.063	63.125	1.00	43.23	C
ATOM	7658	CG1	VAL	B	448	56.556	42.551	62.179	1.00	45.60	C
ATOM	7662	CG2	VAL	B	448	59.015	42.492	62.716	1.00	42.14	C
ATOM	7666	C	VAL	B	448	56.418	45.326	63.165	1.00	43.28	C
ATOM	7667	O	VAL	B	448	56.092	45.929	62.166	1.00	44.31	O
ATOM	7669	N	TYR	B	449	55.689	45.383	64.276	1.00	43.80	N
ATOM	7670	CA	TYR	B	449	54.501	46.281	64.301	1.00	45.14	C
ATOM	7672	CB	TYR	B	449	53.691	46.215	65.614	1.00	44.90	C
ATOM	7675	CG	TYR	B	449	52.313	46.898	65.541	1.00	44.12	C
ATOM	7676	CD1	TYR	B	449	52.189	48.255	65.779	1.00	46.97	C
ATOM	7678	CE1	TYR	B	449	50.943	48.910	65.720	1.00	46.64	C
ATOM	7680	CZ	TYR	B	449	49.815	48.190	65.447	1.00	45.85	C
ATOM	7681	OH	TYR	B	449	48.665	48.911	65.395	1.00	46.60	O
ATOM	7683	CE2	TYR	B	449	49.885	46.829	65.221	1.00	44.32	C
ATOM	7685	CD2	TYR	B	449	51.136	46.187	65.266	1.00	44.41	C
ATOM	7687	C	TYR	B	449	54.789	47.778	63.894	1.00	46.61	C
ATOM	7688	O	TYR	B	449	54.067	48.298	63.000	1.00	47.56	O
ATOM	7690	N	GLU	B	450	55.802	48.442	64.500	1.00	46.75	N
ATOM	7691	CA	GLU	B	450	56.031	49.886	64.271	1.00	46.77	C
ATOM	7693	CB	GLU	B	450	57.232	50.432	65.055	1.00	47.02	C
ATOM	7696	CG	GLU	B	450	57.189	51.947	65.277	1.00	47.82	C
ATOM	7699	CD	GLU	B	450	58.484	52.545	65.899	1.00	49.42	C
ATOM	7700	OE1	GLU	B	450	59.260	51.671	66.456	1.00	51.76	O
ATOM	7701	OE2	GLU	B	450	58.720	53.847	65.828	1.00	42.12	O
ATOM	7702	C	GLU	B	450	56.266	50.117	62.807	1.00	46.93	C
ATOM	7703	O	GLU	B	450	55.646	50.986	62.191	1.00	46.71	O
ATOM	7705	N	LEU	B	451	57.138	49.276	62.251	1.00	46.89	N
ATOM	7706	CA	LEU	B	451	57.477	49.294	60.816	1.00	46.73	C
ATOM	7708	CB	LEU	B	451	58.482	48.152	60.492	1.00	46.28	C
ATOM	7711	CG	LEU	B	451	59.903	48.347	61.060	1.00	44.24	C
ATOM	7713	CD1	LEU	B 451	60.763	47.101	60.918	1.00	42.25	C
ATOM	7717	CD2	LEU	B	451	60.600	49.581	60.468	1.00	42.74	C
ATOM	7721	C	LEU	B	451	56.228	49.244	59.919	1.00	47.03	C
ATOM	7722	O	LEU	B	451	56.016	50.176	59.149	1.00	47.32	O
ATOM	7724	N	LEU	B	452	55.376	48.218	60.099	1.00	47.10	N
ATOM	7725	CA	LEU	B	452	54.067	48.137	59.379	1.00	46.82	C
ATOM	7727	CB	LEU	B	452	53.324	46.825	59.660	1.00	45.75	C
ATOM	7730	CG	LEU	B	452	54.040	45.512	59.327	1.00	46.16	C
ATOM	7732	CD1	LEU	B	452	53.516	44.364	60.152	1.00	43.64	C
ATOM	7736	CD2	LEU	B	452	53.973	45.160	57.846	1.00	45.86	C
ATOM	7740	C	LEU	B	452	53.134	49.344	59.645	1.00	46.45	C
ATOM	7741	O	LEU	B	452	52.453	49.735	58.761	1.00	46.63	O
ATOM	7743	N	GLU	B	453	53.111	49.942	60.832	1.00	47.02	N
ATOM	7744	CA	GLU	B	453	52.306	51.169	61.015	1.00	47.90	C
ATOM	7746	CB	GLU	B	453	52.112	51.543	62.504	1.00	48.34	C
ATOM	7749	CG	GLU	B	453	51.057	52.632	62.779	1.00	49.22	C
ATOM	7752	CD	GLU	B	453	50.411	52.592	64.195	1.00	52.09	C
ATOM	7753	OE1	GLU	B	453	51.162	52.344	65.194	1.00	58.06	O
ATOM	7754	OE2	GLU	B	453	49.143	52.831	64.318	1.00	55.89	O
ATOM	7755	C	GLU	B	453	52.869	52.355	60.211	1.00	46.91	C
ATOM	7756	O	GLU	B	453	52.130	53.220	59.837	1.00	46.20	O
ATOM	7758	N	LYS	B	454	54.166	52.338	59.909	1.00	47.09	N
ATOM	7759	CA	LYS	B	454	54.834	53.390	59.145	1.00	47.08	C
ATOM	7761	CB	LYS	B	454	56.171	53.760	59.815	1.00	47.46	C
ATOM	7764	CG	LYS	B	454	56.225	53.921	61.415	1.00	47.21	C
ATOM	7767	CD	LYS	B	454	55.745	55.278	61.931	1.00	48.77	C
ATOM	7770	CE	LYS	B	454	56.629	55.854	63.085	1.00	50.17	C
ATOM	7773	NZ	LYS	B	454	56.923	54.873	64.195	1.00	51.07	N
ATOM	7777	C	LYS	B	454	55.034	52.974	57.677	1.00	47.19	C
ATOM	7778	O	LYS	B	454	55.969	53.404	57.020	1.00	48.03	O
ATOM	7780	N	ASP	B	455	54.151	52.123	57.163	1.00	47.51	N
ATOM	7781	CA	ASP	B	455	54.164	51.640	55.768	1.00	47.30	C
ATOM	7783	CB	ASP	B	455	53.938	52.815	54.813	1.00	47.68	C
ATOM	7786	CG	ASP	B	455	52.559	53.454	54.985	1.00	49.87	C
ATOM	7787	OD1	ASP	B	455	51.545	52.693	55.063	1.00	50.99	O
ATOM	7788	OD2	ASP	B	455	52.385	54.708	55.004	1.00	52.92	O
ATOM	7789	C	ASP	B	455	55.312	50.716	55.278	1.00	47.15	C
ATOM	7790	O	ASP	B	455	55.389	50.416	54.075	1.00	46.98	O
ATOM	7792	N	TYR	B	456	56.155	50.209	56.183	1.00	46.38	N
ATOM	7793	CA	TYR	B	456	57.193	49.272	55.763	1.00	46.01	C
ATOM	7795	CB	TYR	B	456	58.177	48.922	56.880	1.00	45.30	C
ATOM	7798	CG	TYR	B	456	59.257	47.970	56.385	1.00	43.90	C
ATOM	7799	CD1	TYR	B	456	60.371	48.432	55.661	1.00	43.05	C
ATOM	7801	CE1	TYR	B	456	61.309	47.535	55.153	1.00	44.00	C
ATOM	7803	CZ	TYR	B	456	61.103	46.157	55.386	1.00	43.33	C
ATOM	7804	OH	TYR	B	456	61.934	45.186	54.973	1.00	41.19	O
ATOM	7806	CE2	TYR	B	456	60.028	45.724	56.105	1.00	44.07	C
ATOM	7808	CD2	TYR	B	456	59.122	46.613	56.584	1.00	42.69	C
ATOM	7810	C	TYR	B	456	56.532	47.988	55.299	1.00	46.18	C
ATOM	7811	O	TYR	B	456	55.739	47.438	56.010	1.00	47.32	O
ATOM	7813	N	ARG	B	457	56.863	47.516	54.115	1.00	45.87	N
ATOM	7814	CA	ARG	B	457	56.539	46.162	53.718	1.00	45.60	C
ATOM	7816	CB	ARG	B	457	55.344	46.125	52.767	1.00	45.00	C
ATOM	7819	CG	ARG	B	457	54.072	46.825	53.212	1.00	44.26	C
ATOM	7822	CD	ARG	B	457	53.132	45.939	54.022	1.00	44.61	C
ATOM	7825	NE	ARG	B	457	51.867	46.571	54.412	1.00	43.28	N
ATOM	7827	CZ	ARG	B	457	51.750	47.491	55.356	1.00	43.74	C
ATOM	7828	NH1	ARG	B	457	52.821	47.969	55.988	1.00	44.12	N
ATOM	7831	NH2	ARG	B	457	50.551	47.985	55.648	1.00	43.36	N
ATOM	7834	C	ARG	B	457	57.767	45.558	53.025	1.00	46.59	C
ATOM	7835	O	ARG	B	457	58.593	46.286	52.414	1.00	46.60	O
ATOM	7837	N	MET	B	458	57.823	44.223	53.098	1.00	47.07	N
ATOM	7838	CA	MET	B	458	58.823	43.403	52.448	1.00	47.52	C
ATOM	7840	CB	MET	B	458	58.515	41.912	52.654	1.00	46.61	C
ATOM	7843	CG	MET	B	458	58.680	41.536	54.097	1.00	46.82	C
ATOM	7846	SD	MET	B	458	58.772	39.806	54.462	1.00	49.50	S
ATOM	7847	CE	MET	B	458	57.034	39.367	54.436	1.00	52.19	C
ATOM	7851	C	MET	B	458	58.901	43.704	50.969	1.00	48.40	C
ATOM	7852	O	MET	B	458	57.869	43.829	50.313	1.00	47.93	O
ATOM	7854	N	GLU	B	459	60.136	43.863	50.482	1.00	49.94	N
ATOM	7855	CA	GLU	B	459	60.465	43.939	49.059	1.00	51.52	C
ATOM	7857	CB	GLU	B	459	61.978	44.017	48.864	1.00	51.77	C
ATOM	7860	CG	GLU	B	459	62.653	45.350	49.118	1.00	53.89	C
ATOM	7863	CD	GLU	B	459	64.184	45.195	49.212	1.00	56.32	C
ATOM	7864	OE1	GLU	B	459	64.651	44.347	50.059	1.00	61.08	O
ATOM	7865	OE2	GLU	B	459	64.922	45.939	48.476	1.00	61.82	O
ATOM	7866	C	GLU	B	459	60.040	42.681	48.308	1.00	51.00	C
ATOM	7867	O	GLU	B	459	59.965	41.589	48.878	1.00	50.53	O
ATOM	7869	N	ARG	B	460	59.824	42.852	47.008	1.00	51.42	N
ATOM	7870	CA	ARG	B	460	59.517	41.747	46.112	1.00	52.12	C
ATOM	7872	CB	ARG	B	460	59.191	42.238	44.703	1.00	51.56	C
ATOM	7875	CG	ARG	B	460	58.867	41.133	43.748	1.00	53.27	C
ATOM	7878	CD	ARG	B	460	58.227	41.557	42.401	1.00	55.17	C
ATOM	7881	NE	ARG	B	460	59.137	42.265	41.499	1.00	58.14	N
ATOM	7883	CZ	ARG	B	460	60.200	41.729	40.875	1.00	60.71	C
ATOM	7884	NH1	ARG	B	460	60.555	40.436	41.024	1.00	63.60	N
ATOM	7887	NH2	ARG	B	460	60.939	42.502	40.084	1.00	59.53	N
ATOM	7890	C	ARG	B	460	60.735	40.817	46.110	1.00	51.66	C
ATOM	7891	O	ARG	B	460	61.842	41.308	45.908	1.00	52.31	O
ATOM	7893	N	PRO	B	461	60.564	39.527	46.404	1.00	50.97	N
ATOM	7894	CA	PRO	B	461	61.670	38.586	46.289	1.00	51.56	C
ATOM	7896	CB	PRO	B	461	61.064	37.273	46.789	1.00	51.60	C
ATOM	7899	CG	PRO	B	461	59.939	37.687	47.600	1.00	51.63	C
ATOM	7902	CD	PRO	B	461	59.360	38.881	46.949	1.00	50.26	C
ATOM	7905	C	PRO	B	461	62.135	38.391	44.870	1.00	52.44	C
ATOM	7906	O	PRO	B	461	61.319	38.473	43.965	1.00	53.32	O
ATOM	7907	N	GLU	B	462	63.410	38.080	44.675	1.00	53.32	N
ATOM	7908	CA	GLU	B	462	63.896	37.742	43.347	1.00	55.00	C
ATOM	7910	CB	GLU	B	462	65.366	37.234	43.365	1.00	56.22	C
ATOM	7913	CG	GLU	B	462	66.410	38.183	43.949	1.00	60.07	C
ATOM	7916	CD	GLU	B	462	66.221	39.622	43.490	1.00	65.95	C
ATOM	7917	OE1	GLU	B	462	66.238	39.824	42.249	1.00	71.53	O
ATOM	7918	OE2	GLU	B	462	66.020	40.538	44.347	1.00	68.75	O
ATOM	7919	C	GLU	B	462	63.029	36.654	42.741	1.00	54.43	C
ATOM	7920	O	GLU	B	462	62.689	35.715	43.414	1.00	54.88	O
ATOM	7922	N	GLY	B	463	62.644	36.816	41.490	1.00	54.46	N
ATOM	7923	CA	GLY	B	463	61.936	35.782	40.759	1.00	54.77	C
ATOM	7926	C	GLY	B	463	60.438	35.916	40.849	1.00	55.50	C
ATOM	7927	O	GLY	B	463	59.733	35.283	40.076	1.00	56.51	O
ATOM	7929	N	CYS	B	464	59.937	36.745	41.764	1.00	55.65	N
ATOM	7930	CA	CYS	B	464	58.516	36.818	42.024	1.00	55.75	C
ATOM	7932	CB	CYS	B	464	58.234	37.571	43.317	1.00	55.49	C
ATOM	7935	SG	CYS	B	464	56.483	37.585	43.734	1.00	55.19	S
ATOM	7937	C	CYS	B	464	57.867	37.558	40.872	1.00	55.99	C
ATOM	7938	O	CYS	B	464	58.243	38.693	40.633	1.00	57.00	O
ATOM	7940	N	PRO	B	465	56.906	36.954	40.155	1.00	55.91	N
ATOM	7941	CA	PRO	B	465	56.206	37.657	39.086	1.00	55.39	C
ATOM	7943	CB	PRO	B	465	55.098	36.677	38.734	1.00	55.24	C
ATOM	7946	CG	PRO	B	465	55.657	35.352	39.061	1.00	54.51	C
ATOM	7949	CD	PRO	B	465	56.393	35.571	40.294	1.00	55.51	C
ATOM	7952	C	PRO	B	465	55.609	38.942	39.589	1.00	55.73	C
ATOM	7953	O	PRO	B	465	55.166	38.954	40.707	1.00	56.93	O
ATOM	7954	N	GLU	B	466	55.606	40.009	38.807	1.00	56.49	N
ATOM	7955	CA	GLU	B	466	54.979	41.266	39.245	1.00	57.21	C
ATOM	7957	CB	GLU	B	466	55.014	42.369	38.153	1.00	57.15	C
ATOM	7960	CG	GLU	B	466	54.784	43.809	38.667	1.00	57.94	C
ATOM	7963	CD	GLU	B	466	54.686	44.919	37.545	1.00	60.39	C
ATOM	7964	OE1	GLU	B	466	55.141	44.722	36.373	1.00	63.82	O
ATOM	7965	OE2	GLU	B	466	54.140	46.036	37.836	1.00	62.32	O
ATOM	7966	C	GLU	B	466	53.533	41.095	39.782	1.00	56.91	C
ATOM	7967	O	GLU	B	466	53.201	41.717	40.805	1.00	57.75	O
ATOM	7969	N	LYS	B	467	52.695	40.279	39.128	1.00	55.96	N
ATOM	7970	CA	LYS	B	467	51.253	40.223	39.480	1.00	55.82	C
ATOM	7972	CB	LYS	B	467	50.407	39.508	38.409	1.00	56.45	C
ATOM	7975	CG	LYS	B	467	50.496	40.106	36.968	1.00	58.90	C
ATOM	7978	CD	LYS	B	467	49.677	41.455	36.725	1.00	61.23	C
ATOM	7981	CE	LYS	B	467	50.190	42.236	35.437	1.00	60.98	C
ATOM	7984	NZ	LYS	B	467	49.391	43.432	34.959	1.00	60.57	N
ATOM	7988	C	LYS	B	467	51.042	39.580	40.865	1.00	54.38	C
ATOM	7989	O	LYS	B	467	50.220	40.057	41.665	1.00	54.26	O
ATOM	7991	N	VAL	B	468	51.817	38.532	41.151	1.00	52.45	N
ATOM	7992	CA	VAL	B	468	51.845	37.905	42.480	1.00	50.89	C
ATOM	7994	CB	VAL	B	468	52.756	36.667	42.556	1.00	49.97	C
ATOM	7996	CG1	VAL	B	468	52.663	36.048	43.927	1.00	49.26	C
ATOM	8000	CG2	VAL	B	468	52.377	35.630	41.523	1.00	49.97	C
ATOM	8004	C	VAL	B	468	52.327	38.902	43.543	1.00	50.42	C
ATOM	8005	O	VAL	B	468	51.791	38.933	44.641	1.00	50.86	O
ATOM	8007	N	TYR	B	469	53.341	39.702	43.241	1.00	49.56	N
ATOM	8008	CA	TYR	B	469	53.744	40.711	44.203	1.00	49.49	C
ATOM	8010	CB	TYR	B	469	55.086	41.340	43.854	1.00	48.31	C
ATOM	8013	CG	TYR	B	469	55.537	42.273	44.950	1.00	46.63	C
ATOM	8014	CD1	TYR	B	469	56.017	41.773	46.159	1.00	44.76	C
ATOM	8016	CE1	TYR	B	469	56.417	42.620	47.191	1.00	45.47	C
ATOM	8018	CZ	TYR	B	469	56.318	43.999	47.018	1.00	45.67	C
ATOM	8019	OH	TYR	B	469	56.707	44.844	48.020	1.00	45.88	O
ATOM	8021	CE2	TYR	B	469	55.823	44.521	45.831	1.00	44.67	C
ATOM	8023	CD2	TYR	B	469	55.423	43.651	44.805	1.00	44.44	C
ATOM	8025	C	TYR	B	469	52.650	41.777	44.455	1.00	49.56	C
ATOM	8026	O	TYR	B	469	52.408	42.098	45.605	1.00	49.84	O
ATOM	8028	N	GLU	B	470	51.975	42.280	43.412	1.00	50.08	N
ATOM	8029	CA	GLU	B	470	50.776	43.167	43.604	1.00	51.03	C
ATOM	8031	CB	GLU	B	470	50.042	43.479	42.294	1.00	51.25	C
ATOM	8034	CG	GLU	B	470	50.761	44.178	41.155	1.00	52.80	C
ATOM	8037	CD	GLU	B	470	49.904	44.177	39.865	1.00	54.27	C
ATOM	8038	OE1	GLU	B	470	48.620	44.263	39.963	1.00	57.20	O
ATOM	8039	OE2	GLU	B	470	50.512	44.065	38.748	1.00	57.98	O
ATOM	8040	C	GLU	B	470	49.693	42.555	44.530	1.00	50.19	C
ATOM	8041	O	GLU	B	470	48.992	43.248	45.228	1.00	49.47	O
ATOM	8043	N	LEU	B	471	49.555	41.246	44.468	1.00	50.05	N
ATOM	8044	CA	LEU	B	471	48.568	40.516	45.245	1.00	50.26	C
ATOM	8046	CB	LEU	B	471	48.442	39.125	44.632	1.00	50.49	C
ATOM	8049	CG	LEU	B	471	47.186	38.353	44.948	1.00	52.40	C
ATOM	8051	CD1	LEU	B	471	46.063	38.682	44.017	1.00	53.17	C
ATOM	8055	CD2	LEU	B	471	47.481	36.903	44.856	1.00	54.74	C
ATOM	8059	C	LEU	B	471	48.995	40.438	46.719	1.00	49.96	C
ATOM	8060	O	LEU	B	471	48.180	40.571	47.639	1.00	49.37	O
ATOM	8062	N	MET	B	472	50.288	40.192	46.932	1.00	50.03	N
ATOM	8063	CA	MET	B	472	50.899	40.318	48.270	1.00	49.75	C
ATOM	8065	CB	MET	B	472	52.400	40.062	48.205	1.00	49.58	C
ATOM	8068	CG	MET	B	472	52.765	38.643	48.319	1.00	50.04	C
ATOM	8071	SD	MET	B	472	54.588	38.660	48.414	1.00	51.23	S
ATOM	8072	CE	MET	B	472	54.948	37.798	46.897	1.00	50.71	C
ATOM	8076	C	MET	B	472	50.643	41.681	48.954	1.00	48.16	C
ATOM	8077	O	MET	B	472	50.235	41.719	50.119	1.00	48.22	O
ATOM	8079	N	ARG	B	473	50.845	42.765	48.231	1.00	46.63	N
ATOM	8080	CA	ARG	B	473	50.634	44.086	48.813	1.00	47.12	C
ATOM	8082	CB	ARG	B	473	51.240	45.172	47.934	1.00	46.99	C
ATOM	8085	CG	ARG	B	473	52.727	45.018	47.741	1.00	46.95	C
ATOM	8088	CD	ARG	B	473	53.568	45.322	48.972	1.00	48.50	C
ATOM	8091	NE	ARG	B	473	54.309	46.574	48.824	1.00	49.47	N
ATOM	8093	CZ	ARG	B	473	53.871	47.795	49.135	1.00	51.77	C
ATOM	8094	NH1	ARG	B	473	52.659	48.006	49.626	1.00	57.09	N
ATOM	8097	NH2	ARG	B	473	54.670	48.841	48.960	1.00	51.95	N
ATOM	8100	C	ARG	B	473	49.143	44.358	49.091	1.00	47.30	C
ATOM	8101	O	ARG	B	473	48.779	44.882	50.154	1.00	48.08	O
ATOM	8103	N	ALA	B	474	48.296	43.963	48.148	1.00	47.28	N
ATOM	8104	CA	ALA	B	474	46.858	43.844	48.357	1.00	47.10	C
ATOM	8106	CB	ALA	B	474	46.203	43.046	47.217	1.00	46.89	C
ATOM	8110	C	ALA	B	474	46.547	43.180	49.676	1.00	47.08	C
ATOM	8111	O	ALA	B	474	45.931	43.801	50.502	1.00	48.05	O
ATOM	8113	N	CYS	B	475	47.006	41.943	49.877	1.00	46.53	N
ATOM	8114	CA	CYS	B	475	46.862	41.252	51.155	1.00	46.29	C
ATOM	8116	CB	CYS	B	475	47.602	39.930	51.108	1.00	47.03	C
ATOM	8119	SG	CYS	B	475	46.791	38.773	50.037	1.00	46.81	S
ATOM	8121	C	CYS B	475	47.370	41.986	52.394	1.00	45.96	C
ATOM	8122	O	CYS	B	475	46.812	41.803	53.470	1.00	46.32	O
ATOM	8124	N	TRP	B	476	48.435	42.774	52.253	1.00	45.16	N
ATOM	8125	CA	TRP	B	476	49.005	43.505	53.373	1.00	44.35	C
ATOM	8127	CB	TRP	B	476	50.538	43.489	53.294	1.00	43.69	C
ATOM	8130	CG	TRP	B	476	51.166	42.135	53.267	1.00	42.95	C
ATOM	8131	CD1	TRP	B	476	50.685	40.958	53.826	1.00	42.95	C
ATOM	8133	NE1	TRP	B	476	51.552	39.915	53.589	1.00	41.25	N
ATOM	8135	CE2	TRP	B	476	52.626	40.400	52.890	1.00	42.10	C
ATOM	8136	CD2	TRP	B	476	52.413	41.810	52.688	1.00	41.95	C
ATOM	8137	CE3	TRP	B	476	53.383	42.551	51.997	1.00	40.35	C
ATOM	8139	CZ3	TRP	B	476	54.509	41.906	51.542	1.00	41.78	C
ATOM	8141	CH2	TRP	B	476	54.705	40.507	51.761	1.00	42.29	C
ATOM	8143	CZ2	TRP	B	476	53.774	39.745	52.431	1.00	42.28	C
ATOM	8145	C	TRP	B	476	48.475	44.933	53.528	1.00	44.73	C
ATOM	8146	O	TRP	B	476	49.132	45.766	54.161	1.00	45.30	O
ATOM	8148	N	GLN	B	477	47.279	45.232	53.011	1.00	45.10	N
ATOM	8149	CA	GLN	B	477	46.660	46.557	53.191	1.00	44.33	C
ATOM	8151	CB	GLN	B	477	45.328	46.697	52.439	1.00	44.15	C
ATOM	8154	CG	GLN	B	477	45.390	46.869	50.951	1.00	44.14	C
ATOM	8157	CD	GLN	B	477	46.267	47.992	50.544	1.00	45.70	C
ATOM	8158	OE1	GLN	B	477	45.975	49.174	50.840	1.00	48.54	O
ATOM	8159	NE2	GLN	B	477	47.374	47.654	49.883	1.00	45.18	N
ATOM	8162	C	GLN	B	477	46.369	46.770	54.666	1.00	44.57	C
ATOM	8163	O	GLN	B	477	45.794	45.920	55.300	1.00	42.91	O
ATOM	8165	N	TRP	B	478	46.739	47.949	55.170	1.00	45.68	N
ATOM	8166	CA	TRP	B	478	46.503	48.331	56.549	1.00	46.05	C
ATOM	8168	CB	TRP	B	478	46.877	49.800	56.805	1.00	44.79	C
ATOM	8171	CG	TRP	B	478	46.815	50.101	58.282	1.00	44.68	C
ATOM	8172	CD1	TRP	B	478	45.826	50.765	58.950	1.00	43.03	C
ATOM	8174	NE1	TRP	B	478	46.086	50.754	60.301	1.00	42.19	N
ATOM	8176	CE2	TRP	B	478	47.267	50.096	60.533	1.00	42.05	C
ATOM	8177	CD2	TRP	B	478	47.743	49.642	59.288	1.00	43.64	C
ATOM	8178	CE3	TRP	B	478	48.950	48.912	59.253	1.00	42.44	C
ATOM	8180	CZ3	TRP	B	478	49.624	48.656	60.432	1.00	41.99	C
ATOM	8182	CH2	TRP	B	478	49.119	49.106	61.652	1.00	43.86	C
ATOM	8184	CZ2	TRP	B	478	47.951	49.851	61.724	1.00	43.39	C
ATOM	8186	C	TRP	B	478	45.066	48.075	56.984	1.00	46.83	C
ATOM	8187	O	TRP	B	478	44.876	47.405	58.001	1.00	48.39	O
ATOM	8189	N	ASN	B	479	44.081	48.548	56.210	1.00	47.58	N
ATOM	8190	CA	ASN	B	479	42.655	48.343	56.531	1.00	48.38	C
ATOM	8192	CB	ASN	B	479	41.773	49.455	55.969	1.00	49.73	C
ATOM	8195	CG	ASN	B	479	40.468	49.605	56.752	1.00	54.19	C
ATOM	8196	OD1	ASN	B	479	40.455	50.208	57.827	1.00	61.13	O
ATOM	8197	ND2	ASN	B	479	39.377	49.021	56.241	1.00	57.99	N
ATOM	8200	C	ASN	B	479	42.104	46.992	56.012	1.00	48.60	C
ATOM	8201	O	ASN	B	479	42.282	46.670	54.822	1.00	49.02	O
ATOM	8203	N	PRO	B	480	41.410	46.222	56.850	1.00	47.90	N
ATOM	8204	CA	PRO	B	480	40.840	44.936	56.406	1.00	47.89	C
ATOM	8206	CB	PRO	B	480	40.102	44.449	57.643	1.00	47.90	C
ATOM	8209	CG	PRO	B	480	40.791	45.134	58.780	1.00	47.61	C
ATOM	8212	CD	PRO	B	480	41.119	46.488	58.270	1.00	47.35	C
ATOM	8215	C	PRO	B	480	39.873	45.005	55.208	1.00	48.18	C
ATOM	8216	O	PRO	B	480	39.925	44.141	54.331	1.00	48.11	O
ATOM	8217	N	SER	B	481	39.018	46.032	55.158	1.00	48.48	N
ATOM	8218	CA	SER	B	481	38.078	46.196	54.032	1.00	48.57	C
ATOM	8220	CB	SER	B	481	37.100	47.322	54.277	1.00	48.17	C
ATOM	8223	OG	SER	B	481	37.739	48.562	54.140	1.00	49.08	O
ATOM	8225	C	SER	B	481	38.771	46.377	52.677	1.00	49.17	C
ATOM	8226	O	SER	B	481	38.201	45.959	51.659	1.00	49.48	O
ATOM	8228	N	ASP	B	482	40.004	46.938	52.679	1.00	49.58	N
ATOM	8229	CA	ASP	B	482	40.827	47.113	51.447	1.00	49.26	C
ATOM	8231	CB	ASP	B	482	42.024	48.071	51.609	1.00	49.40	C
ATOM	8234	CG	ASP	B	482	41.651	49.465	52.133	1.00	50.76	C
ATOM	8235	OD1	ASP	B	482	40.531	49.993	51.875	1.00	51.54	O
ATOM	8236	OD2	ASP	B	482	42.497	50.105	52.813	1.00	51.94	O
ATOM	8237	C	ASP	B	482	41.410	45.834	50.882	1.00	48.65	C
ATOM	8238	O	ASP	B	482	41.828	45.838	49.734	1.00	48.82	O
ATOM	8240	N	ARG	B	483	41.482	44.761	51.655	1.00	48.25	N
ATOM	8241	CA	ARG	B	483	42.185	43.571	51.187	1.00	48.07	C
ATOM	8243	CB	ARG	B	483	42.632	42.728	52.350	1.00	48.03	C
ATOM	8246	CG	ARG	B	483	43.693	43.359	53.210	1.00	48.47	C
ATOM	8249	CD	ARG	B	483	43.895	42.633	54.535	1.00	48.62	C
ATOM	8252	NE	ARG	B	483	44.537	43.512	55.501	1.00	49.16	N
ATOM	8254	CZ	ARG	B	483	44.435	43.400	56.824	1.00	51.38	C
ATOM	8255	NH1	ARG	B	483	43.804	42.358	57.380	1.00	52.50	N
ATOM	8258	NH2	ARG	B	483	45.004	44.314	57.618	1.00	49.87	N
ATOM	8261	C	ARG	B	483	41.197	42.774	50.385	1.00	48.15	C
ATOM	8262	O	ARG	B	483	40.048	42.787	50.764	1.00	48.56	O
ATOM	8264	N	PRO	B	484	41.609	42.029	49.350	1.00	48.11	N
ATOM	8265	CA	PRO	B	484	40.670	41.164	48.603	1.00	48.16	C
ATOM	8267	CB	PRO	B	484	41.561	40.497	47.539	1.00	47.97	C
ATOM	8270	CG	PRO	B	484	42.861	40.506	48.145	1.00	47.84	C
ATOM	8273	CD	PRO	B	484	42.973	41.879	48.813	1.00	48.09	C
ATOM	8276	C	PRO	B	484	40.040	40.051	49.414	1.00	47.96	C
ATOM	8277	O	PRO	B	484	40.546	39.719	50.492	1.00	48.09	O
ATOM	8278	N	SER	B	485	38.965	39.485	48.867	1.00	47.74	N
ATOM	8279	CA	SER	B	485	38.386	38.228	49.351	1.00	47.65	C
ATOM	8281	CB	SER	B	485	36.955	38.066	48.844	1.00	47.31	C
ATOM	8284	OC	SER	B	485	36.897	37.963	47.424	1.00	46.10	O
ATOM	8286	C	SER	B	485	39.222	37.055	48.839	1.00	48.37	C
ATOM	8287	O	SER	B	485	39.935	37.184	47.856	1.00	48.58	O
ATOM	8289	N	PHE	B	486	39.106	35.903	49.490	1.00	49.19	N
ATOM	8290	CA	PHE	B	486	39.660	34.647	48.950	1.00	49.76	C
ATOM	8292	CB	PHE	B	486	39.599	33.515	49.981	1.00	49.30	C
ATOM	8295	CG	PHE	B	486	40.568	33.703	51.121	1.00	50.33	C
ATOM	8296	CD1	PHE	B	486	41.954	33.747	50.883	1.00	48.94	C
ATOM	8298	CE1	PHE	B	486	42.839	33.875	51.903	1.00	47.01	C
ATOM	8300	CZ	PHE	B	486	42.382	33.986	53.195	1.00	48.38	C
ATOM	8302	CE2	PHE	B	486	41.028	33.983	53.462	1.00	48.35	C
ATOM	8304	CD2	PHE	B	486 40.124	33.834	52.430	1.00	50.31	C
ATOM	8306	C	PHE	B	486	39.044	34.192	47.628	1.00	50.28	C
ATOM	8307	O	PHE	B	486	39.702	33.471	46.863	1.00	51.07	O
ATOM	8309	N	ALA	B	487	37.806	34.588	47.341	1.00	50.36	N
ATOM	8310	CA	ALA	B	487	37.247	34.302	46.016	1.00	50.69	C
ATOM	8312	CB	ALA	B	487	35.755	34.530	46.003	1.00	50.39	C
ATOM	8316	C	ALA	B	487	37.979	35.102	44.898	1.00	50.78	C
ATOM	8317	O	ALA	B	487	38.420	34.493	43.928	1.00	49.54	O
ATOM	8319	N	GLU	B	488	38.135	36.431	45.085	1.00	51.52	N
ATOM	8320	CA	GLU	B	488	39.005	37.289	44.240	1.00	52.17	C
ATOM	8322	CB	GLU	B	488	39.145	38.688	44.813	1.00	51.76	C
ATOM	8325	CG	GLU	B	488	37.907	39.516	44.683	1.00	53.55	C
ATOM	8328	CD	GLU	B	488	38.055	40.919	45.282	1.00	54.38	C
ATOM	8329	OE1	GLU	B	488 38.337	41.060	46.496	1.00	55.44	O
ATOM	8330	OE2	GLU	B	488	37.839	41.891	44.537	1.00	57.21	O
ATOM	8331	C	GLU	B	488	40.422	36.736	44.054	1.00	52.57	C
ATOM	8332	O	GLU	B	488	40.920	36.674	42.921	1.00	52.92	O
ATOM	8334	N	ILE	B	489	41.051	36.333	45.158	1.00	52.71	N
ATOM	8335	CA	ILE	B	489	42.428	35.817	45.131	1.00	53.14	C
ATOM	8337	CB	ILE	B	489	42.987	35.627	46.603	1.00	53.22	C
ATOM	8339	CG1	ILE	B	489	43.368	36.993	47.203	1.00	52.71	C
ATOM	8342	CD1	ILE	B	489	43.384	37.040	48.717	1.00	51.77	C
ATOM	8346	CG2	ILE	B	489	44.204	34.702	46.652	1.00	52.99	C
ATOM	8350	C	ILE	B	489	42.562	34.534	44.263	1.00	53.84	C
ATOM	8351	O	ILE	B	489	43.386	34.477	43.355	1.00	54.34	O
ATOM	8353	N	HIS	B	490	41.751	33.528	44.549	1.00	54.21	N
ATOM	8354	CA	HIS	B	490	41.764	32.273	43.810	1.00	54.31	C
ATOM	8356	CB	HIS	B	490	40.716	31.326	44.397	1.00	55.03	C
ATOM	8359	CG	HIS	B	490	40.501	30.087	43.597	1.00	54.84	C
ATOM	8360	ND1	HIS	B	490	41.315	28.977	43.714	1.00	56.14	N
ATOM	8362	CE1	HIS	B	490	40.889	28.039	42.890	1.00	57.22	C
ATOM	8364	NE2	HIS	B	490	39.842	28.508	42.234	1.00	57.57	N
ATOM	8366	CD2	HIS	B	490	39.582	29.790	42.658	1.00	54.81	C
ATOM	8368	C	HIS	B	490	41.483	32.468	42.345	1.00	54.84	C
ATOM	8369	O	HIS	B	490	42.070	31.800	41.533	1.00	55.20	O
ATOM	8371	N	GLN	B	491	40.554	33.359	42.017	1.00	55.89	N
ATOM	8372	CA	GLN	B	491	40.334	33.791	40.648	1.00	56.45	C
ATOM	8374	CB	GLN	B	491	39.240	34.837	40.598	1.00	57.05	C
ATOM	8377	CG	GLN	B	491	38.861	35.359	39.224	1.00	59.32	C
ATOM	8380	CD	GLN	B	491	37.944	34.413	38.494	1.00	62.51	C
ATOM	8381	OE1	GLN	B	491	38.357	33.291	38.086	1.00	62.20	O
ATOM	8382	NE2	GLN	B	491	36.678	34.851	38.321	1.00	63.92	N
ATOM	8385	C	GLN	B	491	41.625	34.362	40.082	1.00	56.93	C
ATOM	8386	O	GLN	B	491	42.054	33.934	39.034	1.00	56.92	O
ATOM	8388	N	ALA	B	492	42.277	35.291	40.772	1.00	57.65	N
ATOM	8389	CA	ALA	B	492	43.565	35.795	40.265	1.00	58.86	C
ATOM	8391	CB	ALA	B	492	44.256	36.723	41.272	1.00	58.37	C
ATOM	8395	C	ALA	B	492	44.506	34.646	39.863	1.00	59.63	C
ATOM	8396	O	ALA	B	492	45.083	34.693	38.783	1.00	60.12	O
ATOM	8398	N	PHE	B	493	44.596	33.612	40.715	1.00	60.62	N
ATOM	8399	CA	PHE	B	493	45.524	32.474	40.544	1.00	61.20	C
ATOM	8401	CB	PHE	B	493	45.811	31.756	41.872	1.00	60.84	C
ATOM	8404	CG	PHE	B	493	46.787	32.481	42.736	1.00	60.62	C
ATOM	8405	CD1	PHE	B	493	48.144	32.458	42.438	1.00	60.75	C
ATOM	8407	CE1	PHE	B	493	49.063	33.153	43.247	1.00	60.89	C
ATOM	8409	CZ	PHE	B	493	48.614	33.853	44.357	1.00	59.58	C
ATOM	8411	CE2	PHE	B	493	47.270	33.854	44.653	1.00	58.93	C
ATOM	8413	CD2	PHE	B	493	46.367	33.198	43.841	1.00	59.95	C
ATOM	8415	C	PHE	B	493	45.095	31.444	39.520	1.00	63.06	C
ATOM	8416	O	PHE	B	493	45.962	30.859	38.849	1.00	63.12	O
ATOM	8418	N	GLU	B	494	43.782	31.191	39.433	1.00	64.65	N
ATOM	8419	CA	GLU	B	494	43.219	30.444	38.314	1.00	65.94	C
ATOM	8421	CB	GLU	B	494	41.690	30.316	38.405	1.00	65.82	C
ATOM	8424	CG	GLU	B	494	41.198	28.897	38.755	1.00	67.78	C
ATOM	8427	CD	GLU	B	494	39.682	28.697	38.542	1.00	68.60	C
ATOM	8428	OE1	GLU	B	494	39.075	29.320	37.621	1.00	69.70	O
ATOM	8429	OE2	GLU	B	494	39.080	27.899	39.305	1.00	72.77	O
ATOM	8430	C	GLU	B	494	43.698	31.046	36.963	1.00	65.78	C
ATOM	8431	O	GLU	B	494	44.485	30.390	36.285	1.00	66.61	O
ATOM	8433	N	THR	B	495	43.305	32.281	36.638	1.00	65.70	N
ATOM	8434	CA	THR	B	495	43.771	33.022	35.445	1.00	66.27	C
ATOM	8436	CB	THR	B	495	43.591	34.550	35.668	1.00	66.55	C
ATOM	8438	OG1	THR	B	495	42.235	34.865	36.035	1.00	67.15	O
ATOM	8440	CG2	THR	B	495	43.865	35.370	34.391	1.00	66.40	C
ATOM	8444	C	THR	B	495	45.253	32.777	35.097	1.00	67.37	C
ATOM	8445	O	THR	B	495	45.593	32.295	33.992	1.00	68.13	O
ATOM	8447	N	MET	B	496	46.113	33.062	36.081	1.00	68.02	N
ATOM	8448	CA	MET	B	496	47.569	32.920	35.961	1.00	67.97	C
ATOM	8450	CB	MET	B	496	48.274	33.481	37.192	1.00	67.57	C
ATOM	8453	CG	MET	B	496	48.155	34.951	37.332	1.00	65.98	C
ATOM	8456	SD	MET	B	496	49.115	35.559	38.741	1.00	65.69	S
ATOM	8457	CE	MET	B	496	48.124	35.222	40.160	1.00	62.73	C
ATOM	8461	C	MET	B	496	48.018	31.471	35.754	1.00	68.66	C
ATOM	8462	O	MET	B	496	48.618	31.199	34.750	1.00	69.04	O
ATOM	8464	N	PHE	B	497	47.716	30.547	36.673	1.00	69.72	N
ATOM	8465	CA	PHE	B	497	48.080	29.094	36.512	1.00	70.34	C
ATOM	8467	CB	PHE	B	497	47.719	28.262	37.806	1.00	70.36	C
ATOM	8470	CG	PHE	B	497	47.975	26.747	37.700	1.00	70.15	C
ATOM	8471	CD1	PHE	B	497	49.278	26.237	37.610	1.00	70.56	C
ATOM	8473	CE1	PHE	B	497	49.515	24.808	37.482	1.00	70.09	C
ATOM	8475	CZ	PHE	B	497	48.439	23.906	37.448	1.00	69.28	C
ATOM	8477	CE2	PHE	B	497	47.129	24.400	37.545	1.00	69.73	C
ATOM	8479	CD2	PHE	B	497	46.902	25.825	37.670	1.00	71.15	C
ATOM	8481	C	PHE	B	497	47.540	28.450	35.169	1.00	71.18	C
ATOM	8482	O	PHE	B	497	47.983	27.338	34.786	1.00	71.42	O
ATOM	8484	N	GLN	B	498	46.615	29.140	34.469	1.00	71.40	N
ATOM	8485	CA	GLN	B	498	46.359	28.898	33.037	1.00	71.65	C
ATOM	8487	CB	GLN	B	498	44.851	28.828	32.725	1.00	72.74	C
ATOM	8490	CG	GLN	B	498	43.847	28.239	33.798	1.00	74.51	C
ATOM	8493	CD	GLN	B	498	44.388	27.082	34.648	1.00	77.50	C
ATOM	8494	OE1	GLN	B	498	45.270	26.323	34.203	1.00	79.28	O
ATOM	8495	NE2	GLN	B	498	43.854	26.947	35.882	1.00	77.78	N
ATOM	8498	C	GLN	B	498	47.014	29.997	32.193	1.00	71.23	C
ATOM	8499	O	GLN	B	498	48.215	29.953	31.932	1.00	70.66	O
ATOM	8501	N	LYS	C	234	51.161	5.079	−3.312	1.00	84.86	N
ATOM	8502	CA	LYS	C	234	50.027	4.587	−4.152	1.00	84.92	C
ATOM	8504	CB	LYS	C	234	50.371	4.575	−5.645	1.00	84.78	C
ATOM	8507	CG	LYS	C	234	50.545	5.970	−6.208	1.00	84.60	C
ATOM	8510	CD	LYS	C	234	50.956	5.950	−7.682	1.00	84.78	C
ATOM	8513	CE	LYS	C	234	51.581	7.283	−8.093	1.00	84.70	C
ATOM	8516	NZ	LYS	C	234	51.871	7.382	−9.548	1.00	84.28	N
ATOM	8520	C	LYS	C	234	49.515	3.216	−3.700	1.00	85.24	C
ATOM	8521	O	LYS	C	234	50.263	2.365	−3.200	1.00	84.78	O
ATOM	8525	N	TRP	C	235	48.224	3.016	−3.958	1.00	85.50	N
ATOM	8526	CA	TRP	C	235	47.381	2.035	−3.268	1.00	85.45	C
ATOM	8528	CB	TRP	C	235	45.952	2.617	−3.092	1.00	84.79	C
ATOM	8531	CG	TRP	C	235	45.869	3.990	−2.438	1.00	83.98	C
ATOM	8532	CD1	TRP	C	235	46.366	5.193	−2.912	1.00	83.64	C
ATOM	8534	NE1	TRP	C	235	46.083	6.211	−2.035	1.00	83.11	N
ATOM	8536	CE2	TRP	C	235	45.389	5.693	−0.979	1.00	82.49	C
ATOM	8537	CD2	TRP	C	235	45.232	4.293	−1.209	1.00	82.73	C
ATOM	8538	CE3	TRP	C	235	44.547	3.524	−0.256	1.00	82.49	C
ATOM	8540	CZ3	TRP	C	235	44.046	4.153	0.870	1.00	83.44	C
ATOM	8542	CH2	TRP	C	235	44.206	5.550	1.060	1.00	84.32	C
ATOM	8544	CZ2	TRP	C	235	44.883	6.328	0.145	1.00	83.50	C
ATOM	8546	C	TRP	C	235	47.322	0.719	−4.064	1.00	86.06	C
ATOM	8547	O	TRP	C	235	46.552	−0.210	−3.737	1.00	86.09	O
ATOM	8549	N	GLU	C	236	48.166	0.629	−5.086	1.00	86.66	N
ATOM	8550	CA	GLU	C	236	47.990	−0.326	−6.142	1.00	87.32	C
ATOM	8552	CB	GLU	C	236	48.817	0.068	−7.355	1.00	87.50	C
ATOM	8555	CG	GLU	C	236	48.494	1.443	−7.921	1.00	88.15	C
ATOM	8558	CD	GLU	C	236	47.187	1.514	−8.696	1.00	88.82	C
ATOM	8559	OE1	GLU	C	236	46.855	0.570	−9.457	1.00	87.60	O
ATOM	8560	OE2	GLU	C	236	46.509	2.556	−8.571	1.00	90.25	O
ATOM	8561	C	GLU	C	236	48.490	−1.618	−5.585	1.00	87.71	C
ATOM	8562	O	GLU	C	236	49.439	−1.609	−4.823	1.00	87.64	O
ATOM	8564	N	MET	C	237	47.822	−2.710	−5.922	1.00	88.54	N
ATOM	8565	CA	MET	C	237	48.209	−4.032	−5.447	1.00	89.45	C
ATOM	8567	CB	MET	C	237	47.386	−4.415	−4.218	1.00	89.64	C
ATOM	8570	CG	MET	C	237	45.857	−4.382	−4.406	1.00	89.90	C
ATOM	8573	SD	MET	C	237	45.033	−5.712	−3.492	1.00	90.93	S
ATOM	8574	CE	MET	C	237	45.433	−7.061	−4.384	1.00	90.25	C
ATOM	8578	C	MET	C	237	48.009	−5.048	−6.528	1.00	89.63	C
ATOM	8579	O	MET	C	237	47.304	−4.783	−7.487	1.00	89.93	O
ATOM	8581	N	GLU	C	238	48.590	−6.223	−6.331	1.00	90.33	N
ATOM	8582	CA	GLU	C	238	48.585	−7.291	−7.333	1.00	90.87	C
ATOM	8584	CB	GLU	C	238	49.825	−8.188	−7.129	1.00	90.62	C
ATOM	8587	CG	GLU	C	238	49.892	−9.462	−7.957	1.00	90.54	C
ATOM	8590	CD	GLU	C	238	49.932	−9.205	−9.453	1.00	90.68	C
ATOM	8591	OE1	GLU	C	238	48.896	−8.788	−10.040	1.00	92.10	O
ATOM	8592	OE2	GLU	C	238	51.006	−9.429	−10.046	1.00	88.72	O
ATOM	8593	C	GLU	C	238	47.302	−8.097	−7.171	1.00	91.22	C
ATOM	8594	O	GLU	C	238	47.096	−8.642	−6.092	1.00	91.62	O
ATOM	8596	N	ARG	C	239	46.479	−8.229	−8.221	1.00	91.41	N
ATOM	8597	CA	ARG	C	239	45.197	−8.969	−8.097	1.00	91.90	C
ATOM	8599	CB	ARG	C	239	44.330	−8.842	−9.358	1.00	91.80	C
ATOM	8602	CG	ARG	C	239	44.650	−9.812	−10.504	1.00	91.37	C
ATOM	8605	CD	ARG	C	239	43.938	−9.499	−11.809	1.00	91.13	C
ATOM	8608	NE	ARG	C	239	44.486	−8.314	−12.483	1.00	90.38	N
ATOM	8610	CZ	ARG	C	239	44.040	−7.045	−12.398	1.00	89.51	C
ATOM	8611	NH1	ARG	C	239	42.993	−6.708	−11.645	1.00	88.88	N
ATOM	8614	NH2	ARG	C	239	44.668	−6.086	−13.088	1.00	89.27	N
ATOM	8617	C	ARG	C	239	45.336	−10.459	−7.666	1.00	92.76	C
ATOM	8618	O	ARG	C	239	44.423	−10.983	−7.017	1.00	93.07	O
ATOM	8620	N	THR	C	240	46.456	−11.110	−8.032	1.00	93.35	N
ATOM	8621	CA	THR	C	240	46.890	−12.431	−7.489	1.00	93.82	C
ATOM	8623	CB	THR	C	240	48.349	−12.753	−7.912	1.00	93.80	C
ATOM	8625	OG1	THR	C	240	48.529	−12.458	−9.302	1.00	93.48	O
ATOM	8627	CG2	THR	C	240	48.678	−14.266	−7.766	1.00	93.29	C
ATOM	8631	C	THR	C	240	46.849	−12.587	−5.962	1.00	94.63	C
ATOM	8632	O	THR	C	240	46.531	−13.682	−5.464	1.00	95.01	O
ATOM	8634	N	ASP	C	241	47.217	−11.520	−5.236	1.00	95.30	N
ATOM	8635	CA	ASP	C	241	47.161	−11.491	−3.745	1.00	95.66	C
ATOM	8637	CB	ASP	C	241	47.511	−10.103	−3.171	1.00	95.85	C
ATOM	8640	CG	ASP	C	241	48.958	−9.702	−3.402	1.00	96.55	C
ATOM	8641	OD1	ASP	C	241	49.661	−10.326	4.240	1.00	97.52	O
ATOM	8642	OD2	ASP	C	241	49.468	−8.745	−2.779	1.00	97.25	O
ATOM	8643	C	ASP	C	241	45.800	−11.868	−3.181	1.00	96.34	C
ATOM	8644	O	ASP	C	241	45.731	−12.486	−2.122	1.00	96.64	O
ATOM	8646	N	ILE	C	242	44.739	−11.471	−3.891	1.00	97.13	N
ATOM	8647	CA	ILE	C	242	43.357	−11.621	−3.449	1.00	97.68	C
ATOM	8649	CB	ILE	C	242	42.579	−10.273	−3.727	1.00	97.53	C
ATOM	8651	CG1	ILE	C	242	42.828	−9.326	−2.539	1.00	97.60	C
ATOM	8654	CD1	ILE	C	242	42.359	−7.914	−2.715	1.00	97.66	C
ATOM	8658	CG2	ILE	C	242	41.070	−10.486	−3.975	1.00	97.64	C
ATOM	8662	C	ILE	C	242	42.688	−12.892	−4.035	1.00	98.04	C
ATOM	8663	O	ILE	C	242	42.739	−13.128	−5.251	1.00	98.30	O
ATOM	8665	N	THR	C	243	42.086	−13.698	−3.144	1.00	98.38	N
ATOM	8666	CA	THR	C	243	41.250	−14.847	−3.508	1.00	98.44	C
ATOM	8668	CB	THR	C	243	41.141	−15.895	−2.322	1.00	98.54	C
ATOM	8670	OG1	THR	C	243	42.442	−16.311	−1.868	1.00	97.80	O
ATOM	8672	CG2	THR	C	243	40.488	−17.202	2.780	1.00	98.33	C
ATOM	8676	C	THR	C	243	39.867	−14.288	−3.841	1.00	98.81	C
ATOM	8677	O	THR	C	243	39.232	−13.673	−2.981	1.00	98.69	O
ATOM	8679	N	MET	C	244	39.417	−14.475	−5.080	1.00	99.22	N
ATOM	8680	CA	MET	C	244	38.030	−14.169	−5.444	1.00	99.77	C
ATOM	8682	CB	MET	C	244	37.907	−13.907	−6.950	1.00	100.08	C
ATOM	8685	CG	MET	C	244	38.687	−12.680	−7.415	1.00	100.91	C
ATOM	8688	SD	MET	C	244	38.463	−11.154	−6.350	1.00	103.39	S
ATOM	8689	CE	MET	C	244	36.662	−10.947	−6.325	1.00	102.89	C
ATOM	8693	C	MET	C	244	37.116	−15.304	−4.992	1.00	99.81	C
ATOM	8694	O	MET	C	244	37.443	−16.478	−5.213	1.00	99.88	O
ATOM	8696	N	LYS	C	245	35.991	−14.943	−4.351	1.00	99.88	N
ATOM	8697	CA	LYS	C	245	35.077	−15.899	−3.684	1.00	99.95	C
ATOM	8699	CB	LYS	C	245	35.139	−15.733	−2.163	1.00	99.90	C
ATOM	8702	CG	LYS	C	245	36.526	−15.978	1.559	1.00	99.53	C
ATOM	8705	CD	LYS	C	245	36.455	−16.198	−0.025	1.00	99.67	C
ATOM	8708	CE	LYS	C	245	37.304	−17.390	0.454	1.00	98.83	C
ATOM	8711	NZ	LYS	C	245	37.046	−17.716	1.894	1.00	98.04	N
ATOM	8715	C	LYS	C	245	33.603	−15.885	−4.190	1.00	100.18	C
ATOM	8716	O	LYS	C	245	33.170	−16.886	−4.793	1.00	100.45	O
ATOM	8718	N	HIS	C	246	32.832	−14.811	−3.936	1.00	100.00	N
ATOM	8719	CA	HIS	C	246	31.441	−14.722	−4.456	1.00	99.79	C
ATOM	8721	CB	HIS	C	246	30.484	−15.648	−3.673	1.00	99.90	C
ATOM	8724	CG	HIS	C	246	30.236	−15.239	−2.252	1.00	100.29	C
ATOM	8725	ND1	HIS	C	246	29.176	−14.436	1.886	1.00	100.70	N
ATOM	8727	CE1	HIS	C	246	29.187	−14.262	0.576	1.00	100.31	C
ATOM	8729	NE2	HIS	C	246	30.210	−14.933	−0.076	1.00	100.44	N
ATOM	8731	CD2	HIS	C	246	30.876	−15.562	1.102	1.00100.68	C
ATOM	8733	C	HIS	C	246	30.827	−13.321	−4.569	1.00	99.47	C
ATOM	8734	O	HIS	C	246	31.271	−12.390	−3.915	1.00	99.03	O
ATOM	8736	N	LYS	C	247	29.802	−13.228	−5.427	1.00	99.43	N
ATOM	8737	CA	LYS	C	247	28.957	−12.017	−5.661	1.00	99.45	C
ATOM	8739	CB	LYS	C	247	27.947	−12.289	−6.822	1.00	99.46	C
ATOM	8742	CG	LYS	C	247	26.634	−11.451	−6.936	1.00	99.38	C
ATOM	8745	CD	LYS	C	247	25.562	−12.201	−7.758	1.00	99.19	C
ATOM	8748	CE	LYS	C	247	24.199	−11.546	−7.634	1.00	98.82	C
ATOM	8751	NZ	LYS	C	247	24.245	−10.137	−8.111	1.00	98.80	N
ATOM	8755	C	LYS	C	247	28.239	−11.559	−4.384	1.00	99.32	C
ATOM	8756	O	LYS	C	247	27.975	−12.357	−3.483	1.00	99.35	O
ATOM	8758	N	LEU	C	248	27.922	−10.268	−4.329	1.00	99.34	N
ATOM	8759	CA	LEU	C	248	27.407	−9.629	−3.114	1.00	99.22	C
ATOM	8761	CB	LEU	C	248	28.536	−9.560	−2.059	1.00	99.35	C
ATOM	8764	CG	LEU	C	248	28.159	−9.351	−0.580	1.00	99.81	C
ATOM	8766	CD1	LEU	C	248	29.043	−10.214	0.371	1.00	99.31	C
ATOM	8770	CD2	LEU	C	248	28.172	−7.838	−0.173	1.00	100.61	C
ATOM	8774	C	LEU	C	248	26.857	−8.218	−3.407	1.00	99.06	C
ATOM	8775	O	LEU	C	248	25.662	−7.946	−3.277	1.00	98.76	O
ATOM	8777	N	GLY	C	254	24.384	−6.467	−7.591	1.00	108.36	N
ATOM	8778	CA	GLY	C	254	25.451	−5.599	−8.104	1.00	108.51	C
ATOM	8781	C	GLY	C	254	26.846	−6.211	−8.142	1.00	108.59	C
ATOM	8782	O	GLY	C	254	27.044	−7.356	−7.686	1.00	108.70	O
ATOM	8784	N	GLU	C	255	27.812	−5.418	−8.639	1.00	108.45	N
ATOM	8785	CA	GLU	C	255	29.218	−5.854	−8.911	1.00	108.34	C
ATOM	8787	CB	GLU	C	255	29.758	−5.083	−10.140	1.00	108.26	C
ATOM	8790	CG	GLU	C	255	28.939	−5.286	−11.415	1.00	109.15	C
ATOM	8793	CD	GLU	C	255	28.803	−6.756	−11.842	1.00	110.72	C
ATOM	8794	OE1	GLU	C	255	29.692	−7.591	−11.506	1.00	110.51	O
ATOM	8795	OE2	GLU	C	255	27.793	−7.085	−12.515	1.00	111.23	O
ATOM	8796	C	GLU	C	255	30.227	−5.811	−7.714	1.00	107.99	C
ATOM	8797	O	GLU	C	255	31.435	−5.555	−7.877	1.00	107.25	O
ATOM	8799	N	VAL	C	256	29.703	−6.122	−6.526	1.00	107.88	N
ATOM	8800	CA	VAL	C	256	30.454	−6.183	−5.272	1.00	107.97	C
ATOM	8802	CB	VAL	C	256	29.633	−5.545	−4.096	1.00	107.99	C
ATOM	8804	CG1	VAL	C	256	30.308	−5.763	−2.713	1.00	108.35	C
ATOM	8808	CG2	VAL	C	256	29.400	−4.045	−4.348	1.00	108.16	C
ATOM	8812	C	VAL	C	256	30.768	−7.671	−5.004	1.00	107.74	C
ATOM	8813	O	VAL	C	256	29.921	−8.554	−5.256	1.00	107.77	O
ATOM	8815	N	TYR	C	257	31.983	−7.934	−4.514	1.00	107.19	N
ATOM	8816	CA	TYR	C	257	32.472	−9.292	−4.302	1.00	106.96	C
ATOM	8818	CB	TYR	C	257	33.331	−9.729	−5.513	1.00	107.49	C
ATOM	8821	CG	TYR	C	257	32.518	−10.065	−6.777	1.00	108.24	C
ATOM	8822	CD	TYR	C	257	32.095	−9.049	−7.668	1.00	108.98	C
ATOM	8824	CE1	TYR	C	257	31.328	−9.353	−8.833	1.00	108.46	C
ATOM	8826	CZ	TYR	C	257	30.997	−10.681	−9.111	1.00	108.09	C
ATOM	8827	OH	TYR	C	257	30.263	−10.958	−10.234	1.00	108.03	O
ATOM	8829	CE2	TYR	C	257	31.406	−11.710	−8.253	1.00	108.05	C
ATOM	8831	CD2	TYR	C	257	32.166	−11.400	−7.089	1.00	108.45	C
ATOM	8833	C	TYR	C	257	33.252	−9.402	−2.979	1.00	106.19	C
ATOM	8834	O	TYR	C	257	34.246	−8.701	−2.790	1.00	105.86	O
ATOM	8836	N	GLU	C	258	32.784	−10.259	−2.062	1.00	105.32	N
ATOM	8837	CA	GLU	C	258	33.590	−10.648	−0.907	1.00	104.86	C
ATOM	8839	CB	GLU	C	258	32.860	−11.570	0.080	1.00	104.83	C
ATOM	8842	CG	GLU	C	258	33.647	−11.806	1.379	1.00	104.93	C
ATOM	8845	CD	GLU	C	258	33.613	−13.241	1.910	1.00	104.95	C
ATOM	8846	OE1	GLU	C	258	33.985	−14.192	1.188	1.00	105.36	O
ATOM	8847	OE2	GLU	C	258	33.249	−13.421	3.085	1.00	104.39	O
ATOM	8848	C	GLU	C	258	34.774	−11.397	−1.471	1.00	104.59	C
ATOM	8849	O	GLU	C	258	34.597	−12.419	−2.137	1.00	104.59	O
ATOM	8851	N	GLY	C	259	35.959	−10.841	−1.265	1.00	104.01	N
ATOM	8852	CA	GLY	C	259	37.198	−11.559	−1.483	1.00	103.54	C
ATOM	8855	C	GLY	C	259	37.780	−11.997	−0.157	1.00	103.14	C
ATOM	8856	O	GLY	C	259	37.152	−11.880	0.902	1.00	103.00	O
ATOM	8858	N	VAL	C	260	38.976	−12.562	−0.251	1.00	102.66	N
ATOM	8859	CA	VAL	C	260	39.933	−12.614	0.852	1.00	102.10	C
ATOM	8861	CB	VAL	C	260	40.083	−14.086	1.401	1.00	102.14	C
ATOM	8863	CG1	VAL	C	260	41.466	−14.380	2.010	1.00	101.62	C
ATOM	8867	CG2	VAL	C	260	38.974	−14.371	2.424	1.00	101.91	C
ATOM	8871	C	VAL	C	260	41.224	−11.982	0.301	1.00	101.87	C
ATOM	8872	O	VAL	C	260	41.472	−12.057	−0.901	1.00	101.80	O
ATOM	8874	N	TRP	C	261	41.979	−11.306	1.172	1.00	101.46	N
ATOM	8875	CA	TRP	C	261	43.363	−10.883	0.906	1.00	101.15	C
ATOM	8877	CB	TRP	C	261	43.607	−9.452	1.424	1.00	100.56	C
ATOM	8880	CG	TRP	C	261	44.820	−8.751	0.859	1.00	100.08	C
ATOM	8881	CD1	TRP	C	261	46.019	−9.314	0.508	1.00	99.76	C
ATOM	8883	NE1	TRP	C	261	46.878	−8.349	0.038	1.00	99.88	N
ATOM	8885	CE2	TRP	C	261	46.257	−7.128	0.090	1.00	99.91	C
ATOM	8886	CD2	TRP	C	261	44.954	−7.343	0.609	1.00	100.10	C
ATOM	8887	CE3	TRP	C	261	44.095	−6.230	0.755	1.00	99.78	C
ATOM	8889	CZ3	TRP	C	261	44.568	−4.948	0.385	1.00	99.66	C
ATOM	8891	CH2	TRP	C	261	45.877	−4.776	−0.121	1.00	99.48	C
ATOM	8893	CZ2	TRP	C	261	46.731	−5.844	−0.276	1.00	99.65	C
ATOM	8895	C	TRP	C	261	44.226	−11.944	1.612	1.00	101.19	C
ATOM	8896	O	TRP	C	261	44.649	−11.759	2.763	1.00	101.16	O
ATOM	8898	N	LYS	C	262	44.470	−13.051	0.892	1.00	101.20	N
ATOM	8899	CA	LYS	C	262	45.018	−14.337	1.437	1.00	100.96	C
ATOM	8901	CB	LYS	C	262	45.228	−15.345	0.272	1.00	100.90	C
ATOM	8904	CG	LYS	C	262	45.455	−16.811	0.659	1.00	100.96	C
ATOM	8907	CD	LYS	C	262	44.226	−17.514	1.252	1.00	100.64	C
ATOM	8910	CE	LYS	C	262	44.633	−18.893	1.816	1.00	100.87	C
ATOM	8913	NZ	LYS	C	262	43.535	−19.675	2.475	1.00	100.56	N
ATOM	8917	C	LYS	C	262	46.296	−14.217	2.320	1.00	100.80	C
ATOM	8918	O	LYS	C	262	46.505	−15.024	3.228	1.00	100.85	O
ATOM	8920	N	LYS	C	263	47.124	−13.211	2.028	1.00	100.60	N
ATOM	8921	CA	LYS	C	263	48.274	−12.755	2.866	1.00	100.26	C
ATOM	8923	CB	LYS	C	263	48.863	−11.503	2.191	1.00	100.47	C
ATOM	8926	CG	LYS	C	263	50.044	−10.758	2.825	1.00	100.44	C
ATOM	8929	CD	LYS	C	263	50.305	−9.545	1.911	1.00	100.63	C
ATOM	8932	CE	LYS	C	263	51.438	−8.650	2.334	1.00	100.87	C
ATOM	8935	NZ	LYS	C	263	51.427	−7.416	1.478	1.00	100.34	N
ATOM	8939	C	LYS	C	263	47.950	−12.444	4.347	1.00	99.91	C
ATOM	8940	O	LYS	C	263	48.749	−12.766	5.226	1.00	99.93	O
ATOM	8942	N	TYR	C	264	46.804	−11.805	4.599	1.00	99.27	N
ATOM	8943	CA	TYR	C	264	46.383	−11.395	5.945	1.00	98.82	C
ATOM	8945	CB	TYR	C	264	45.985	−9.913	5.942	1.00	98.51	C
ATOM	8948	CG	TYR	C	264	46.981	−8.964	5.277	1.00	98.09	C
ATOM	8949	CD1	TYR	C	264	48.279	−8.790	5.778	1.00	97.70	C
ATOM	8951	CE1	TYR	C	264	49.196	−7.886	5.159	1.00	97.83	C
ATOM	8953	CZ	TYR	C	264	48.804	−7.154	4.037	1.00	97.99	C
ATOM	8954	OH	TYR	C	264	49.659	−6.270	3.408	1.00	97.04	O
ATOM	8956	CE2	TYR	C	264	47.524	−7.322	3.530	1.00	98.60	C
ATOM	8958	CD2	TYR	C	264	46.615	−8.215	4.155	1.00	98.55	C
ATOM	8960	C	TYR	C	264	45.220	−12.285	6.406	1.00	98.17	C
ATOM	8961	O	TYR	C	264	44.418	−11.920	7.266	1.00	97.16	O
ATOM	8963	N	THR	C	267	39.439	−11.242	5.086	1.00	99.88	N
ATOM	8964	CA	THR	C	267	38.257	−10.991	4.264	1.00	99.96	C
ATOM	8966	CB	THR	C	267	36.983	−11.599	4.941	1.00	99.78	C
ATOM	8968	OG1	THR	C	267	37.096	−13.029	4.981	1.00	99.22	O
ATOM	8970	CG2	THR	C	267	35.719	−11.381	4.112	1.00	99.73	C
ATOM	8974	C	THR	C	267	38.110	−9.482	3.952	1.00	100.07	C
ATOM	8975	O	THR	C	267	38.279	−8.631	4.839	1.00	99.68	O
ATOM	8977	N	VAL	C	268	37.819	−9.182	2.678	1.00	100.39	N
ATOM	8978	CA	VAL	C	268	37.606	−7.806	2.172	1.00	100.41	C
ATOM	8980	CB	VAL	C	268	38.913	−7.181	1.584	1.00	100.39	C
ATOM	8982	CG1 VAL	C	268	39.827	−6.698	2.699	1.00	100.54	C
ATOM	8986	CG2	VAL	C	268	39.654	−8.154	0.667	1.00	100.69	C
ATOM	8990	C	VAL	C	268	36.471	−7.719	1.127	1.00	100.62	C
ATOM	8991	O	VAL	C	268	36.095	−8.730	0.514	1.00	100.73	O
ATOM	8993	N	ALA	C	269	35.937	−6.506	0.955	1.00	100.66	N
ATOM	8994	CA	ALA	C	269	34.895	−6.222	−0.021	1.00	100.97	C
ATOM	8996	CB	ALA	C	269	33.877	−5.299	0.567	1.00	101.03	C
ATOM	9000	C	ALA	C	269	35.572	−5.600	−1.235	1.00	101.13	C
ATOM	9001	O	ALA	C	269	36.315	−4.637	−1.089	1.00	101.10	O
ATOM	9003	N	VAL	C	270	35.324	−6.169	−2.420	1.00	101.70	N
ATOM	9004	CA	VAL	C	270	36.025	−5.817	−3.676	1.00	102.13	C
ATOM	9006	CB	VAL	C	270	36.998	−6.957	−4.133	1.00	102.14	C
ATOM	9008	CG1	VAL	C	270	37.547	−6.727	−5.542	1.00	101.98	C
ATOM	9012	CG2	VAL	C	270	38.151	−7.090	−3.151	1.00	102.21	C
ATOM	9016	C	VAL	C	270	35.020	−5.481	−4.796	1.00	102.60	C
ATOM	9017	O	VAL	C	270	34.208	−6.337	−5.167	1.00	102.80	O
ATOM	9019	N	LYS	C	271	35.109	−4.258	−5.338	1.00	103.03	N
ATOM	9020	CA	LYS	C	271	34.179	−3.746	−6.359	1.00	103.33	C
ATOM	9022	CB	LYS	C	271	33.759	−2.290	−6.035	1.00	103.24	C
ATOM	9025	CG	LYS	C	271	33.252	−1.490	−7.262	1.00	103.58	C
ATOM	9028	CD	LYS	C	271	32.318	−0.341	−6.950	1.00	103.33	C
ATOM	9031	CE	LYS	C	271	31.850	0.292	−8.250	1.00	102.48	C
ATOM	9034	NZ	LYS	C	271	30.685	1.115	−7.974	1.00	103.09	N
ATOM	9038	C	LYS	C	271	34.833	−3.833	−7.751	1.00	103.68	C
ATOM	9039	O	LYS	C	271	35.926	−3.315	−7.922	1.00	103.32	O
ATOM	9041	N	THR	C	272	34.121	−4.421	−8.729	1.00	104.18	N
ATOM	9042	CA	THR	C	272	34.618	−4.642	−10.115	1.00	104.48	C
ATOM	9044	CB	THR	C	272	34.731	−6.195	−10.452	1.00	104.62	C
ATOM	9046	OG1	THR	C	272	35.540	−6.390	−11.620	1.00	104.99	O
ATOM	9048	CG2	THR	C	272	33.376	−6.856	−10.830	1.00	104.16	C
ATOM	9052	C	THR	C	272	33.798	−3.895	−11.194	1.00	104.84	C
ATOM	9053	O	THR	C	272	32.619	−3.570	−10.976	1.00	104.74	O
ATOM	9055	N	LEU	C	273	34.447	−3.662	−12.349	1.00	105.16	N
ATOM	9056	CA	LEU	C	273	33.908	−2.897	−13.493	1.00	105.15	C
ATOM	9058	CB	LEU	C	273	34.895	−1.787	−13.890	1.00	105.19	C
ATOM	9061	CG	LEU	C	273	34.521	−0.752	−14.975	1.00	105.28	C
ATOM	9063	CD1	LEU	C	273	33.257	0.030	−14.681	1.00	105.26	C
ATOM	9067	CD2	LEU	C	273	35.670	0.225	−15.203	1.00	105.19	C
ATOM	9071	C	LEU	C	273	33.668	−3.836	−14.684	1.00	105.40	C
ATOM	9072	O	LEU	C	273	34.472	−4.753	−14.934	1.00	105.48	O
ATOM	9074	N	LYS	C	274	32.592	−3.573	−15.438	1.00	105.39	N
ATOM	9075	CA	LYS	C	274	32.065	−4.521	−16.448	1.00	105.24	C
ATOM	9077	CB	LYS	C	274	30.558	−4.266	−16.698	1.00	105.27	C
ATOM	9080	CG	LYS	C	274	29.675	−4.302	−15.411	1.00	105.20	C
ATOM	9083	CD	LYS	C	274	28.191	−4.025	−15.698	1.00	105.02	C
ATOM	9086	CE	LYS	C	274	27.350	−4.012	−14.428	1.00	104.29	C
ATOM	9089	NZ	LYS	C	274	27.736	−2.929	−13.483	1.00	103.53	N
ATOM	9093	C	LYS	C	274	32.869	−4.464	−17.753	1.00	105.09	C
ATOM	9094	O	LYS	C	274	32.383	−4.826	−18.830	1.00	104.84	O
ATOM	9096	N	ASP	C	276	35.241	−3.799	−19.931	1.00	100.89	N
ATOM	9097	CA	ASP	C	276	35.626	−2.705	−20.846	1.00	100.82	C
ATOM	9099	CB	ASP	C	276	35.925	−3.262	−22.265	1.00	100.90	C
ATOM	9102	CG	ASP	C	276	34.764	−4.076	−22.860	1.00	100.82	C
ATOM	9103	OD1	ASP	C	276	34.413	−5.145	−22.302	1.00	100.23	O
ATOM	9104	OD2	ASP	C	276	34.162	−3.730	−23.897	1.00	100.56	O
ATOM	9105	C	ASP	C	276	34.644	−1.498	−20.939	1.00	100.83	C
ATOM	9106	O	ASP	C	276	34.994	−0.466	−21.530	1.00	100.85	O
ATOM	9108	N	THR	C	277	33.464	−1.594	−20.316	1.00	100.64	N
ATOM	9109	CA	THR	C	277	32.297	−0.797	−20.735	1.00	100.50	C
ATOM	9111	CB	THR	C	277	30.975	−1.542	−20.343	1.00	100.49	C
ATOM	9113	OG1	THR	C	277	30.951	−2.833	−20.975	1.00	100.09	O
ATOM	9115	CG2	THR	C	277	29.706	−0.850	−20.894	1.00	100.30	C
ATOM	9119	C	THR	C	277	32.292	0.694	−20.285	1.00	100.56	C
ATOM	9120	O	THR	C	277	32.822	1.047	−19.219	1.00	100.64	O
ATOM	9122	N	MET	C	278	31.705	1.516	−21.174	1.00	100.38	N
ATOM	9123	CA	MET	C	278	31.380	2.979	−21.083	1.00	100.16	C
ATOM	9125	CB	MET	C	278	29.871	3.166	−21.318	1.00	100.17	C
ATOM	9128	CG	MET	C	278	29.471	3.092	−22.784	1.00	101.06	C
ATOM	9131	SD	MET	C	278	27.691	3.284	−22.990	1.00	102.76	S
ATOM	9132	CE	MET	C	278	27.050	1.702	−22.153	1.00	102.46	C
ATOM	9136	C	MET	C	278	31.775	3.893	−19.913	1.00	99.41	C
ATOM	9137	O	MET	C	278	32.518	4.861	−20.112	1.00	99.48	O
ATOM	9139	N	GLU	C	279	31.235	3.626	−18.725	1.00	98.50	N
ATOM	9140	CA	GLU	C	279	31.389	4.522	−17.553	1.00	97.55	C
ATOM	9142	CB	GLU	C	279	30.063	4.561	−16.754	1.00	97.90	C
ATOM	9145	CG	GLU	C	279	28.897	5.263	−17.484	1.00	98.44	C
ATOM	9148	CD	GLU	C	279	27.518	4.724	−17.074	1.00	99.13	C
ATOM	9149	OE1	GLU	C 279	27.188	3.580	−17.489	1.00	101.98	O
ATOM	9150	OE2	GLU	C 279	26.762	5.422	−16.339	1.00	99.66	O
ATOM	9151	C	GLU	C	279	32.632	4.140	−16.692	1.00	96.00	C
ATOM	9152	O	GLU	C	279	32.555	4.014	−15.470	1.00	95.28	O
ATOM	9154	N	VAL	C	280	33.775	4.001	−17.374	1.00	94.45	N
ATOM	9155	CA	VAL	C	280	35.097	3.737	−16.777	1.00	93.59	C
ATOM	9157	CB	VAL	C	280	36.198	3.456	−17.881	1.00	93.13	C
ATOM	9159	CG1	VAL	C	280	37.595	3.243	−17.266	1.00	92.50	C
ATOM	9163	CG2	VAL	C	280	35.806	2.256	−18.785	1.00	93.44	C
ATOM	9167	C	VAL	C	280	35.546	4.933	−15.940	1.00	91.75	C
ATOM	9168	O	VAL	C	280	36.192	4.775	−14.907	1.00	91.50	O
ATOM	9170	N	GLU	C	281	35.224	6.133	−16.405	1.00	90.30	N
ATOM	9171	CA	GLU	C	281	35.582	7.332	−15.686	1.00	88.98	C
ATOM	9173	CB	GLU	C	281	35.353	8.560	−16.572	1.00	88.85	C
ATOM	9176	CG	GLU	C	281	35.815	9.872	−15.959	1.00	90.21	C
ATOM	9179	CD	GLU	C	281	37.148	9.766	−15.214	1.00	91.90	C
ATOM	9180	OE1	GLU	C	281	38.147	9.338	−15.874	1.00	92.80	O
ATOM	9181	OE2	GLU	C	281	37.179	10.100	−13.988	1.00	90.02	O
ATOM	9182	C	GLU	C	281	34.867	7.450	−14.324	1.00	87.72	C
ATOM	9183	O	GLU	C	281	35.468	7.900	−13.350	1.00	87.59	O
ATOM	9185	N	GLU	C	282	33.613	7.011	−14.253	1.00	86.25	N
ATOM	9186	CA	GLU	C	282	32.860	7.029	−13.003	1.00	85.24	C
ATOM	9188	CB	GLU	C	282	31.431	6.515	−13.180	1.00	85.21	C
ATOM	9191	CG	GLU	C	282	30.548	7.259	−14.171	1.00	85.95	C
ATOM	9194	CD	GLU	C	282	30.460	8.745	−13.908	1.00	87.00	C
ATOM	9195	OE1	GLU	C	282	30.426	9.147	−12.725	1.00	87.53	O
ATOM	9196	OE2	GLU	C	282	30.421	9.514	−14.895	1.00	88.12	O
ATOM	9197	C	GLU	C	282	33.532	6.151	−11.975	1.00	84.64	C
ATOM	9198	O	GLU	C	282	33.686	6.547	−10.825	1.00	85.03	O
ATOM	9200	N	PHE	C	283	33.925	4.957	−12.401	1.00	83.65	N
ATOM	9201	CA	PHE	C	283	34.620	3.995	−11.544	1.00	82.99	C
ATOM	9203	CB	PHE	C	283	34.991	2.782	−12.374	1.00	83.26	C
ATOM	9206	CG	PHE	C	283	35.366	1.600	−11.578	1.00	83.65	C
ATOM	9207	CD1	PHE	C	283	34.394	0.682	−11.186	1.00	84.25	C
ATOM	9209	CE1	PHE	C	283	34.749	−0.459	−10.470	1.00	85.52	C
ATOM	9211	CZ	PHE	C	283	36.105	−0.685	−10.142	1.00	85.31	C
ATOM	9213	CE2	PHE	C	283	37.079	0.224	−10.551	1.00	84.69	C
ATOM	9215	CD2	PHE	C	283	36.704	1.359	−11.263	1.00	84.21	C
ATOM	9217	C	PHE	C	283	35.872	4.613	−10.934	1.00	82.29	C
ATOM	9218	O	PHE	C	283	36.105	4.566	−9.712	1.00	81.85	O
ATOM	9220	N	LEU	C	284	36.653	5.225	−11.811	1.00	81.41	N
ATOM	9221	CA	LEU	C	284	37.845	5.923	−11.401	1.00	80.93	C
ATOM	9223	CB	LEU	C	284	38.697	6.302	−12.616	1.00	80.65	C
ATOM	9226	CG	LEU	C	284	39.420	5.138	−13.302	1.00	78.38	C
ATOM	9228	CD1	LEU	C	284	39.918	5.580	−14.627	1.00	76.78	C
ATOM	9232	CD2	LEU	C	284	40.571	4.623	−12.459	1.00	77.49	C
ATOM	9236	C	LEU	C	284	37.584	7.139	−10.495	1.00	81.17	C
ATOM	9237	O	LEU	C	284	38.293	7.269	−9.507	1.00	81.27	O
ATOM	9239	N	LYS	C	285	36.596	8.007	−10.793	1.00	81.33	N
ATOM	9240	CA	LYS	C	285	36.178	9.061	−9.812	1.00	81.30	C
ATOM	9242	CB	LYS	C	285	35.007	9.937	−10.302	1.00	81.06	C
ATOM	9245	CG	LYS	C	285	35.422	11.235	−11.006	1.00	81.70	C
ATOM	9248	CD	LYS	C	285	34.722	12.505	−10.454	1.00	80.22	C
ATOM	9251	CE	LYS	C	285	35.368	13.793	−11.032	1.00	79.42	C
ATOM	9254	NZ	LYS	C	285	35.194	14.966	−10.156	1.00	77.51	N
ATOM	9258	C	LYS	C	285	35.840	8.493	−8.406	1.00	81.57	C
ATOM	9259	O	LYS	C	285	36.190	9.109	−7.401	1.00	81.77	O
ATOM	9261	N	GLU	C	286	35.224	7.311	−8.352	1.00	81.38	N
ATOM	9262	CA	GLU	C	286	34.880	6.684	−7.091	1.00	81.53	C
ATOM	9264	CB	GLU	C	286	33.965	5.480	−7.316	1.00	81.68	C
ATOM	9267	CG	GLU	C	286	33.207	5.051	−6.081	1.00	81.50	C
ATOM	9270	CD	GLU	C	286	32.427	3.760	−6.256	1.00	82.69	C
ATOM	9271	OE1	GLU	C	286	32.273	3.269	−7.400	1.00	81.77	O
ATOM	9272	OE2	GLU	C	286	31.944	3.233	−5.217	1.00	87.14	O
ATOM	9273	C	GLU	C	286	36.129	6.271	−6.290	1.00	81.65	C
ATOM	9274	O	GLU	C	286	36.240	6.612	−5.106	1.00	81.94	O
ATOM	9276	N	ALA	C	287	37.056	5.548	−6.930	1.00	81.64	N
ATOM	9277	CA	ALA	C	287	38.339	5.171	−6.299	1.00	81.16	C
ATOM	9279	CB	ALA	C	287	39.245	4.470	−7.292	1.00	80.91	C
ATOM	9283	C	ALA	C	287	39.035	6.407	−5.730	1.00	81.03	C
ATOM	9284	O	ALA	C	287	39.408	6.426	−4.563	1.00	81.57	O
ATOM	9286	N	ALA	C	288	39.122	7.455	−6.546	1.00	80.81	N
ATOM	9287	CA	ALA	C	288	39.813	8.696	−6.206	1.00	80.72	C
ATOM	9289	CB	ALA	C	288	39.877	9.580	−7.419	1.00	80.90	C
ATOM	9293	C	ALA	C	288	39.209	9.475	−5.043	1.00	80.79	C
ATOM	9294	O	ALA	C	288	39.939	10.133	−4.317	1.00	80.49	O
ATOM	9296	N	VAL	C	289	37.886	9.436	−4.887	1.00	81.36	N
ATOM	9297	CA	VAL	C	289	37.220	9.983	−3.683	1.00	81.52	C
ATOM	9299	CB	VAL	C	289	35.658	10.008	−3.795	1.00	81.36	C
ATOM	9301	CG1	VAL	C	289	34.962	10.338	−2.406	1.00	81.72	C
ATOM	9305	CG2	VAL	C	289	35.220	11.026	−4.844	1.00	81.07	C
ATOM	9309	C	VAL	C	289	37.652	9.191	−2.445	1.00	81.83	C
ATOM	9310	O	VAL	C	289	38.088	9.792	−1.461	1.00	81.84	O
ATOM	9312	N	MET	C	290	37.542	7.863	−2.507	1.00	82.18	N
ATOM	9313	CA	MET	C	290	37.907	6.987	−1.378	1.00	82.68	C
ATOM	9315	CB	MET	C	290	37.620	5.538	−1.731	1.00	82.45	C
ATOM	9318	CG	MET	C	290	36.156	5.229	−1.871	1.00	82.92	C
ATOM	9321	SD	MET	C	290	35.864	3.459	−1.850	1.00	82.66	S
ATOM	9322	CE	MET	C	290	34.174	3.303	−2.618	1.00	83.15	C
ATOM	9326	C	MET	C	290	39.366	7.121	−0.849	1.00	83.48	C
ATOM	9327	O	MET	C	290	39.639	6.856	0.342	1.00	84.08	O
ATOM	9329	N	LYS	C	291	40.278	7.544	−1.729	1.00	83.75	N
ATOM	9330	CA	LYS	C	291	41.650	7.895	−1.357	1.00	83.84	C
ATOM	9332	CB	LYS	C	291	42.520	8.030	−2.632	1.00	83.93	C
ATOM	9335	CG	LYS	C	291	42.704	6.740	−3.451	1.00	83.65	C
ATOM	9338	CD	LYS	C	291	43.407	7.008	−4.791	1.00	83.63	C
ATOM	9341	CE	LYS	C	291	43.795	5.708	−5.536	1.00	83.90	C
ATOM	9344	NZ	LYS	C	291	44.183	5.879	−7.001	1.00	82.56	N
ATOM	9348	C	LYS	C	291	41.815	9.178	−0.494	1.00	84.12	C
ATOM	9349	O	LYS	C	291	42.919	9.433	−0.030	1.00	84.75	O
ATOM	9351	N	GLU	C	292	40.771	9.988	−0.294	1.00	84.59	N
ATOM	9352	CA	GLU	C	292	40.839	11.265	0.502	1.00	85.16	C
ATOM	9354	CB	GLU	C	292	40.205	12.440	−0.297	1.00	85.84	C
ATOM	9357	CG	GLU	C	292	40.640	12.654	−1.760	1.00	87.07	C
ATOM	9360	CD	GLU	C	292	42.015	13.272	−1.934	1.00	88.47	C
ATOM	9361	OE1	GLU	C	292	42.611	13.696	−0.926	1.00	89.14	O
ATOM	9362	OE2	GLU	C	292	42.499	13.331	−3.099	1.00	90.13	O
ATOM	9363	C	GLU	C	292	40.109	11.224	1.892	1.00	85.46	C
ATOM	9364	O	GLU	C	292	40.016	12.271	2.588	1.00	85.32	O
ATOM	9366	N	ILE	C	293	39.579	10.051	2.276	1.00	85.38	N
ATOM	9367	CA	ILE	C	293	38.576	9.943	3.345	1.00	85.03	C
ATOM	9369	CB	ILE	C	293	37.117	9.688	2.767	1.00	84.91	C
ATOM	9371	CG1	ILE	C	293	36.957	8.296	2.117	1.00	84.84	C
ATOM	9374	CD1	ILE	C	293	35.563	8.007	1.542	1.00	84.81	C
ATOM	9378	CG2	ILE	C	293	36.728	10.815	1.796	1.00	84.36	C
ATOM	9382	C	ILE	C	293	39.011	8.869	4.326	1.00	85.06	C
ATOM	9383	O	ILE	C	293	39.334	7.741	3.908	1.00	85.46	O
ATOM	9385	N	LYS	C	294	39.035	9.239	5.613	1.00	84.87	N
ATOM	9386	CA	LYS	C	294	39.474	8.368	6.708	1.00	84.53	C
ATOM	9388	CB	LYS	C	294	40.950	8.663	7.056	1.00	84.40	C
ATOM	9391	CG	LYS	C	294	41.664	7.516	7.716	1.00	84.15	C
ATOM	9394	CD	LYS	C	294	43.006	7.922	8.303	1.00	84.31	C
ATOM	9397	CE	LYS	C	294	43.656	6.763	9.084	1.00	83.87	C
ATOM	9400	NZ	LYS	C	294	45.123	6.933	9.192	1.00	83.28	N
ATOM	9404	C	LYS	C	294	38.552	8.636	7.893	1.00	84.42	C
ATOM	9405	O	LYS	C	294	38.587	9.734	8.459	1.00	84.14	O
ATOM	9407	N	HIS	C	295	37.696	7.659	8.217	1.00	84.45	N
ATOM	9408	CA	HIS	C	295	36.768	7.741	9.370	1.00	84.30	C
ATOM	9410	CB	HIS	C	295	35.633	8.732	9.066	1.00	84.68	C
ATOM	9413	CG	HIS	C	295	34.858	9.145	10.270	1.00	84.83	C
ATOM	9414	ND1	HIS	C	295	33.906	8.334	10.840	1.00	84.57	N
ATOM	9416	CE1	HIS	C	295	33.390	8.937	11.890	1.00	85.47	C
ATOM	9418	NE2	HIS	C	295	33.974	10.114	12.026	1.00	85.78	N
ATOM	9420	CD2	HIS	C	295	34.899	10.268	11.023	1.00	85.29	C
ATOM	9422	C	HIS	C	295	36.174	6.343	9.689	1.00	84.03	C
ATOM	9423	O	HIS	C	295	35.891	5.585	8.756	1.00	84.23	O
ATOM	9425	N	PRO	C	296	35.994	5.975	10.961	1.00	83.71	N
ATOM	9426	CA	PRO	C	296	35.501	4.621	11.272	1.00	83.67	C
ATOM	9428	CB	PRO	C	296	35.956	4.396	12.732	1.00	83.24	C
ATOM	9431	CG	PRO	C	296	36.028	5.738	13.322	1.00	83.35	C
ATOM	9434	CD	PRO	C	296	36.326	6.708	12.200	1.00	83.94	C
ATOM	9437	C	PRO	C	296	33.995	4.371	11.093	1.00	83.72	C
ATOM	9438	O	PRO	C	296	33.537	3.290	11.468	1.00	84.53	O
ATOM	9439	N	ASN	C	297	33.234	5.335	10.568	1.00	83.07	N
ATOM	9440	CA	ASN	C	297	31.884	5.081	10.031	1.00	82.79	C
ATOM	9442	CB	ASN	C	297	30.834	5.758	10.874	1.00	82.41	C
ATOM	9445	CG	ASN	C	297	30.949	5.387	12.295	1.00	80.98	C
ATOM	9446	OD1	ASN	C	297	31.191	6.246	13.133	1.00	80.80	O
ATOM	9447	ND2	ASN	C	297	30.821	4.099	12.591	1.00	77.48	N
ATOM	9450	C	ASN	C	297	31.753	5.465	8.560	1.00	82.84	C
ATOM	9451	O	ASN	C	297	30.671	5.855	8.104	1.00	82.20	O
ATOM	9453	N	LEU	C	298	32.888	5.356	7.848	1.00	83.10	N
ATOM	9454	CA	LEU	C	298	32.971	5.276	6.389	1.00	83.04	C
ATOM	9456	CB	LEU	C	298	33.848	6.399	5.847	1.00	82.80	C
ATOM	9459	CG	LEU	C	298	33.422	7.831	6.152	1.00	83.15	C
ATOM	9461	CD1	LEU	C	298	34.525	8.812	5.783	1.00	83.39	C
ATOM	9465	CD2	LEU	C	298	32.156	8.195	5.409	1.00	83.91	C
ATOM	9469	C	LEU	C	298	33.642	3.956	6.096	1.00	83.10	C
ATOM	9470	O	LEU	C	298	34.708	3.687	6.661	1.00	83.47	O
ATOM	9472	N	VAL	C	299	33.033	3.117	5.265	1.00	83.23	N
ATOM	9473	CA	VAL	C	299	33.712	1.899	4.810	1.00	83.99	C
ATOM	9475	CB	VAL	C	299	32.786	0.994	3.935	1.00	83.47	C
ATOM	9477	CG1	VAL	C	299	32.363	1.660	2.668	1.00	84.36	C
ATOM	9481	CG2	VAL	C	299	33.458	−0.313	3.603	1.00	83.89	C
ATOM	9485	C	VAL	C	299	35.086	2.293	4.157	1.00	84.34	C
ATOM	9486	O	VAL	C	299	35.114	3.102	3.236	1.00	84.19	O
ATOM	9488	N	GLN	C	300	36.202	1.793	4.724	1.00	85.15	N
ATOM	9489	CA	GLN	C	300	37.594	2.247	4.393	1.00	85.42	C
ATOM	9491	CB	GLN	C	300	38.551	2.012	5.561	1.00	85.44	C
ATOM	9494	CG	GLN	C	300	40.012	2.492	5.361	1.00	85.30	C
ATOM	9497	CD	GLN	C	300	40.191	3.984	5.534	1.00	86.17	C
ATOM	9498	OE1	GLN	C	300	39.772	4.773	4.689	1.00	85.60	O
ATOM	9499	NE2	GLN	C	300	40.828	4.377	6.640	1.00	87.22	N
ATOM	9502	C	GLN	C	300	38.222	1.575	3.169	1.00	86.32	C
ATOM	9503	O	GLN	C	300	38.295	0.352	3.109	1.00	86.15	O
ATOM	9505	N	LEU	C	301	38.739	2.403	2.255	1.00	87.35	N
ATOM	9506	CA	LEU	C	301	39.483	1.955	1.084	1.00	87.93	C
ATOM	9508	CB	LEU	C	301	39.600	3.079	0.048	1.00	87.94	C
ATOM	9511	CG	LEU	C	301	40.529	2.915	−1.179	1.00	87.74	C
ATOM	9513	CD1	LEU	C	301	39.862	2.041	−2.211	1.00	87.12	C
ATOM	9517	CD2	LEU	C	301	40.999	4.272	−1.781	1.00	87.33	C
ATOM	9521	C	LEU	C	301	40.863	1.533	1.554	1.00	88.89	C
ATOM	9522	O	LEU	C	301	41.549	2.317	2.223	1.00	88.74	O
ATOM	9524	N	LEU	C	302	41.248	0.304	1.188	1.00	89.99	N
ATOM	9525	CA	LEU	C	302	42.517	−0.319	1.596	1.00	91.16	C
ATOM	9527	CB	LEU	C	302	42.293	−1.774	2.074	1.00	91.12	C
ATOM	9530	CG	LEU	C	302	41.389	−2.061	3.288	1.00	91.10	C
ATOM	9532	CD1	LEU	C	302	41.454	−3.549	3.654	1.00	91.13	C
ATOM	9536	CD2	LEU	C	302	41.752	−1.209	4.495	1.00	90.37	C
ATOM	9540	C	LEU	C	302	43.513	−0.301	0.426	1.00	91.99	C
ATOM	9541	O	LEU	C	302	44.646	0.156	0.563	1.00	92.67	O
ATOM	9543	N	GLY	C	303	43.085	−0.834	−0.711	1.00	92.59	N
ATOM	9544	CA	GLY	C	303	43.860	−0.796	−1.943	1.00	92.82	C
ATOM	9547	C	GLY	C	303	42.980	−0.508	−3.134	1.00	93.16	C
ATOM	9548	O	GLY	C	303	41.748	−0.367	−3.005	1.00	93.17	O
ATOM	9550	N	VAL	C	304	43.636	−0.394	−4.290	1.00	93.28	N
ATOM	9551	CA	VAL	C	304	42.973	−0.369	−5.604	1.00	93.02	C
ATOM	9553	CB	VAL	C	304	42.904	1.096	−6.214	1.00	93.03	C
ATOM	9555	CG1	VAL	C	304	42.186	2.059	−5.269	1.00	93.17	C
ATOM	9559	CG2	VAL	C	304	44.291	1.645	−6.591	1.00	92.49	C
ATOM	9563	C	VAL	C	304	43.736	−1.303	−6.534	1.00	92.96	C
ATOM	9564	O	VAL	C	304	44.642	−2.044	−6.106	1.00	93.24	O
ATOM	9566	N	CYS	C	305	43.328	−1.289	−7.796	1.00	92.69	N
ATOM	9567	CA	CYS	C	305	44.228	−1.603	−8.911	1.00	92.47	C
ATOM	9569	CB	CYS	C	305	44.451	−3.103	−9.056	1.00	92.39	C
ATOM	9572	SC	CYS	C	305	43.066	−4.049	−8.444	1.00	90.89	S
ATOM	9574	C	CYS	C	305	43.662	−0.947	−10.184	1.00	92.60	C
ATOM	9575	O	CYS	C	305	42.544	−1.268	−10.615	1.00	92.41	O
ATOM	9577	N	THR	C	306	44.416	0.021	−10.712	1.00	92.67	N
ATOM	9578	CA	THR	C	306	44.011	0.850	−11.848	1.00	92.76	C
ATOM	9580	CB	THR	C	306	43.475	2.261	−11.355	1.00	92.56	C
ATOM	9582	OG1	THR	C	306	44.459	2.938	−10.573	1.00	93.21	O
ATOM	9584	CG2	THR	C	306	42.300	2.139	−10.374	1.00	91.24	C
ATOM	9588	C	THR	C	306	45.204	0.913	−12.849	1.00	92.99	C
ATOM	9589	O	THR	C	306	45.743	1.988	−13.163	1.00	92.97	O
ATOM	9591	N	ARG	C	307	45.604	−0.286	−13.304	1.00	93.31	N
ATOM	9592	CA	ARG	C	307	46.707	−0.517	−14.258	1.00	93.28	C
ATOM	9594	CB	ARG	C	307	47.810	−1.358	−13.609	1.00	93.84	C
ATOM	9597	CG	ARG	C	307	48.458	−0.723	−12.382	1.00	95.22	C
ATOM	9600	CD	ARG	C	307	49.180	0.592	−12.670	1.00	97.34	C
ATOM	9603	NE	ARG	C	307	49.671	1.286	−11.474	1.00	97.61	N
ATOM	9605	CZ	ARG	C	307	50.232	2.509	−11.476	1.00	99.72	C
ATOM	9606	NH1	ARG	C	307	50.403	3.196	−12.617	1.00	101.42	N
ATOM	9609	NH2	ARG	C	307	50.644	3.062	−10.332	1.00	99.75	N
ATOM	9612	C	ARG	C	307	46.217	−1.222	−15.525	1.00	93.16	C
ATOM	9613	O	ARG	C	307	46.427	−0.710	−16.625	1.00	93.34	O
ATOM	9615	N	GLU	C	308	45.581	−2.388	−15.367	1.00	92.61	N
ATOM	9616	CA	GLU	C	308	44.915	−3.114	−16.465	1.00	92.40	C
ATOM	9618	CB	GLU	C	308	45.757	−4.334	−16.867	1.00	92.53	C
ATOM	9621	CG	GLU	C	308	47.184	−4.034	−17.373	1.00	92.41	C
ATOM	9624	CD	GLU	C	308	48.320	−4.730	−16.597	1.00	91.68	C
ATOM	9625	OE1	GLU	C	308	48.223	−4.918	−15.347	1.00	90.95	O
ATOM	9626	OE2	GLU	C	308	49.342	−5.052	−17.245	1.00	88.64	O
ATOM	9627	C	GLU	C	308	43.511	−3.592	−16.022	1.00	92.15	C
ATOM	9628	O	GLU	C	308	43.261	−3.674	−14.823	1.00	92.01	O
ATOM	9630	N	PRO	C	309	42.591	−3.887	−16.954	1.00	92.14	N
ATOM	9631	CA	PRO	C	309	41.321	−4.592	−16.630	1.00	92.09	C
ATOM	9633	CE	PRO	C	309	40.690	−4.826	−18.008	1.00	91.93	C
ATOM	9636	CG	PRO	C	309	41.192	−3.701	−18.823	1.00	92.00	C
ATOM	9639	CD	PRO	C	309	42.616	−3.493	−18.376	1.00	92.16	C
ATOM	9642	C	PRO	C	309	41.458	−5.945	−15.912	1.00	92.14	C
ATOM	9643	O	PRO	C	309	42.584	−6.437	−15.765	1.00	92.29	O
ATOM	9644	N	PRO	C	310	40.332	−6.545	−15.489	1.00	92.18	N
ATOM	9645	CA	PRO	C	310	39.238	−5.811	−14.839	1.00	92.25	C
ATOM	9647	CE	PRO	C	310	38.274	−6.926	−14.412	1.00	92.12	C
ATOM	9650	CG	PRO	C	310	39.140	−8.108	−14.185	1.00	91.93	C
ATOM	9653	CD	PRO	C	310	40.248	−7.989	−15.183	1.00	92.22	C
ATOM	9656	C	PRO	C	310	39.724	−5.018	−13.621	1.00	92.32	C
ATOM	9657	O	PRO	C	310	40.419	−5.584	−12.772	1.00	92.31	O
ATOM	9658	N	PHE	C	311	39.375	−3.729	−13.555	1.00	92.21	N
ATOM	9659	CA	PHE	C	311	39.746	−2.882	−12.413	1.00	92.09	C
ATOM	9661	CB	PHE	C	311	39.547	−1.388	−12.700	1.00	92.42	C
ATOM	9664	CG	PHE	C	311	40.360	−0.869	−13.864	1.00	93.34	C
ATOM	9665	CD1	PHE	C	311	41.756	−1.048	−13.905	1.00	93.57	C
ATOM	9667	CE1	PHE	C	311	42.533	−0.548	−14.976	1.00	92.67	C
ATOM	9669	CZ	PHE	C	311	41.917	0.122	−16.023	1.00	92.85	C
ATOM	9671	CE2	PHE	C	311	40.512	0.312	−16.004	1.00	93.36	C
ATOM	9673	CD2	PHE	C	311	39.742	−0.182	−14.923	1.00	93.83	C
ATOM	9675	C	PHE	C	311	38.903	−3.273	−11.202	1.00	91.71	C
ATOM	9676	O	PHE	C	311	37.706	−3.574	−11.336	1.00	91.53	O
ATOM	9678	N	TYR	C	312	39.554	−3.288	−10.038	1.00	91.20	N
ATOM	9679	CA	TYR	C	312	38.928	−3.593	−8.769	1.00	90.49	C
ATOM	9681	CE	TYR	C	312	39.545	−4.847	−8.144	1.00	90.91	C
ATOM	9684	CG	TYR	C	312	39.337	−6.184	−8.834	1.00	90.84	C
ATOM	9685	CD1	TYR	C	312	38.110	−6.518	−9.458	1.00	91.22	C
ATOM	9687	CE1	TYR	C	312	37.926	−7.792	−10.072	1.00	92.03	C
ATOM	9689	CZ	TYR	C	312	38.968	−8.745	−10.027	1.00	92.15	C
ATOM	9690	OH	TYR	C	312	38.771	−9.973	−10.618	1.00	91.23	O
ATOM	9692	CE2	TYR	C	312	40.190	−8.440	−9.388	1.00	91.24	C
ATOM	9694	CD2	TYR	C	312	40.358	−7.172	−8.788	1.00	90.88	C
ATOM	9696	C	TYR	C	312	39.170	−2.433	−7.808	1.00	90.16	C
ATOM	9697	O	TYR	C	312	40.242	−1.808	−7.867	1.00	90.00	O
ATOM	9699	N	ILE	C	313	38.194	−2.176	−6.924	1.00	89.63	N
ATOM	9700	CA	ILE	C	313	38.387	−1.366	−5.682	1.00	89.39	C
ATOM	9702	CE	ILE	C	313	37.358	−0.178	−5.591	1.00	89.36	C
ATOM	9704	CG1	ILE	C	313	37.629	0.838	−6.735	1.00	89.57	C
ATOM	9707	CD1	ILE	C	313	36.619	2.005	−6.926	1.00	89.51	C
ATOM	9711	CG2	ILE	C	313	37.443	0.498	−4.208	1.00	89.15	C
ATOM	9715	C	ILE	C	313	38.311	−2.311	−4.454	1.00	89.06	C
ATOM	9716	O	ILE	C	313	37.475	−3.207	−4.453	1.00	89.05	O
ATOM	9718	N	ILE	C	314	39.172	−2.079	−3.438	1.00	88.44	N
ATOM	9719	CA	ILE	C	314	39.324	−2.934	−2.224	1.00	87.99	C
ATOM	9721	CE	ILE	C	314	40.779	−3.598	−2.172	1.00	87.83	C
ATOM	9723	CG1	ILE	C	314	41.060	−4.429	−3.441	1.00	86.23	C
ATOM	9726	CD1	ILE	C	314	41.724	−3.697	−4.562	1.00	84.95	C
ATOM	9730	CG2	ILE	C	314	40.951	−4.475	−0.887	1.00	88.16	C
ATOM	9734	C	ILE	C	314	39.003	−2.136	−0.921	1.00	87.48	C
ATOM	9735	O	ILE	C	314	39.612	−1.108	−0.644	1.00	87.48	O
ATOM	9737	N	THR	C	315	38.040	−2.620	−0.141	1.00	87.12	N
ATOM	9738	CA	THR	C	315	37.628	−1.978	1.120	1.00	86.89	C
ATOM	9740	CB	THR	C	315	36.275	−1.256	0.960	1.00	86.53	C
ATOM	9742	OG1	THR	C	315	35.257	−2.195	0.584	1.00	86.33	O
ATOM	9744	CG2	THR	C	315	36.294	−0.257	−0.170	1.00	86.32	C
ATOM	9748	C	THR	C	315	37.534	−3.012	2.246	1.00	86.80	C
ATOM	9749	O	THR	C	315	37.877	−4.179	2.051	1.00	86.76	O
ATOM	9751	N	GLU	C	316	37.113	−2.571	3.433	1.00	86.79	N
ATOM	9752	CA	GLU	C	316	36.806	−3.495	4.538	1.00	86.54	C
ATOM	9754	CB	GLU	C	316	36.905	−2.827	5.916	1.00	86.52	C
ATOM	9757	CG	GLU	C	316	35.863	−1.772	6.245	1.00	86.61	C
ATOM	9760	CD	GLU	C	316	36.200	−1.022	7.517	1.00	86.68	C
ATOM	9761	OE1	GLU	C	316	36.892	−1.616	8.394	1.00	85.47	O
ATOM	9762	OE2	GLU	C	316	35.777	0.158	7.624	1.00	85.42	O
ATOM	9763	C	GLU	C	316	35.442	−4.155	4.366	1.00	86.06	C
ATOM	9764	O	GLU	C	316	34.471	−3.507	3.953	1.00	86.19	O
ATOM	9766	N	PHE	C	317	35.392	−5.443	4.709	1.00	85.49	N
ATOM	9767	CA	PHE	C	317	34.172	−6.230	4.678	1.00	84.92	C
ATOM	9769	CB	PHE	C	317	34.495	−7.745	4.633	1.00	84.90	C
ATOM	9772	CG	PHE	C	317	33.302	−8.621	4.311	1.00	85.05	C
ATOM	9773	CD1	PHE	C	317	32.553	−8.403	3.135	1.00	85.38	C
ATOM	9775	CE1	PHE	C	317	31.431	−9.200	2.826	1.00	85.11	C
ATOM	9777	CZ	PHE	C	317	31.062	−10.249	3.684	1.00	85.25	C
ATOM	9779	CE2	PHE	C	317	31.814	−10.487	4.870	1.00	84.79	C
ATOM	9781	CD2	PHE	C	317	32.927	−9.674	5.172	1.00	84.54	C
ATOM	9783	C	PHE	C	317	33.376	−5.846	5.923	1.00	84.24	C
ATOM	9784	O	PHE	C	317	33.946	−5.733	7.003	1.00	83.85	O
ATOM	9786	N	MET	C	318	32.087	−5.570	5.731	1.00	83.83	N
ATOM	9787	CA	MET	C	318	31.137	−5.298	6.798	1.00	83.70	C
ATOM	9789	CB	MET	C	318	30.418	−3.955	6.565	1.00	83.48	C
ATOM	9792	CG	MET	C	318	31.346	−2.682	6.394	1.00	83.11	C
ATOM	9795	SD	MET	C	318	32.376	−2.013	7.823	1.00	81.83	S
ATOM	9796	CE	MET	C	318	31.217	−2.174	9.211	1.00	81.59	C
ATOM	9800	C	MET	C	318	30.167	−6.495	6.759	1.00	83.94	C
ATOM	9801	O	MET	C	318	29.463	−6.693	5.748	1.00	84.32	O
ATOM	9803	N	THR	C	319	30.142	−7.261	7.861	1.00	83.69	N
ATOM	9804	CA	THR	C	319	29.595	−8.639	7.931	1.00	83.56	C
ATOM	9806	CB	THR	C	319	29.991	−9.265	9.310	1.00	83.70	C
ATOM	9808	OG1	THR	C	319	31.420	−9.355	9.387	1.00	83.22	O
ATOM	9810	CG2	THR	C	319	29.516	−10.729	9.486	1.00	83.74	C
ATOM	9814	C	THR	C	319	28.087	−8.825	7.683	1.00	83.59	C
ATOM	9815	O	THR	C	319	27.685	−9.863	7.136	1.00	83.60	O
ATOM	9817	N	TYR	C	320	27.268	−7.852	8.091	1.00	83.42	N
ATOM	9818	CA	TYR	C	320	25.806	−7.958	7.978	1.00	83.17	C
ATOM	9820	CB	TYR	C	320	25.157	−7.657	9.333	1.00	83.46	C
ATOM	9823	CG	TYR	C	320	25.235	−8.774	10.363	1.00	84.01	C
ATOM	9824	CD1	TYR	C	320	24.911	−10.111	10.030	1.00	84.90	C
ATOM	9826	CE1	TYR	C	320	24.960	−11.154	11.001	1.00	84.37	C
ATOM	9828	CZ	TYR	C	320	25.306	−10.855	12.322	1.00	84.33	C
ATOM	9829	OH	TYR	C	320	25.341	−11.873	13.248	1.00	83.75	O
ATOM	9831	CE2	TYR	C	320	25.614	−9.530	12.689	1.00	84.41	C
ATOM	9833	CD2	TYR	C	320	25.574	−8.496	11.707	1.00	84.47	C
ATOM	9835	C	TYR	C	320	25.142	−7.144	6.847	1.00	83.05	C
ATOM	9836	O	TYR	C	320	23.930	−7.282	6.637	1.00	83.20	O
ATOM	9838	N	GLY	C	321	25.896	−6.322	6.115	1.00	82.56	N
ATOM	9839	CA	GLY	C	321	25.395	−5.753	4.846	1.00	82.09	C
ATOM	9842	C	GLY	C	321	24.358	−4.640	4.957	1.00	81.49	C
ATOM	9843	O	GLY	C	321	24.407	−3.865	5.901	1.00	81.37	O
ATOM	9845	N	ASN	C	322	23.409	−4.585	4.008	1.00	81.02	N
ATOM	9846	CA	ASN	C	322	22.479	−3.429	3.866	1.00	80.75	C
ATOM	9848	CB	ASN	C	322	21.835	−3.339	2.465	1.00	80.57	C
ATOM	9851	CG	ASN	C	322	20.545	−4.113	2.350	1.00	80.95	C
ATOM	9852	OD1	ASN	C	322	19.456	−3.541	2.458	1.00	80.49	O
ATOM	9853	ND2	ASN	C	322	20.656	−5.427	2.177	1.00	81.05	N
ATOM	9856	C	ASN	C	322	21.413	−3.251	4.981	1.00	80.02	C
ATOM	9857	O	ASN	C	322	20.684	−4.195	5.381	1.00	80.29	O
ATOM	9859	N	LEU	C	323	21.312	−2.015	5.445	1.00	79.02	N
ATOM	9860	CA	LEU	C	323	20.506	−1.684	6.597	1.00	78.19	C
ATOM	9862	CB	LEU	C	323	20.880	−0.296	7.089	1.00	77.86	C
ATOM	9865	CG	LEU	C	323	20.253	0.236	8.348	1.00	77.61	C
ATOM	9867	CD1	LEU	C	323	20.475	−0.736	9.479	1.00	78.62	C
ATOM	9871	CD2	LEU	C	323	20.857	1.583	8.661	1.00	77.66	C
ATOM	9875	C	LEU	C	323	19.001	−1.797	6.329	1.00	78.14	C
ATOM	9876	O	LEU	C	323	18.295	−2.294	7.187	1.00	77.83	O
ATOM	9878	N	LEU	C	324	18.528	−1.403	5.135	1.00	78.17	N
ATOM	9879	CA	LEU	C	324	17.086	−1.479	4.784	1.00	78.17	C
ATOM	9881	CB	LEU	C	324	16.827	−1.074	3.333	1.00	77.78	C
ATOM	9884	CG	LEU	C	324	15.365	−1.026	2.833	1.00	78.07	C
ATOM	9886	CD1	LEU	C	324	14.469	−0.175	3.718	1.00	79.07	C
ATOM	9890	CD2	LEU	C	324	15.282	−0.487	1.410	1.00	78.50	C
ATOM	9894	C	LEU	C	324	16.502	−2.870	4.997	1.00	78.66	C
ATOM	9895	O	LEU	C	324	15.457	−3.018	5.631	1.00	78.63	O
ATOM	9897	N	ASP	C	325	17.193	−3.877	4.465	1.00	79.37	N
ATOM	9898	CA	ASP	C	325	16.776	−5.271	4.605	1.00	79.67	C
ATOM	9900	CB	ASP	C	325	17.438	−6.167	3.551	1.00	79.61	C
ATOM	9903	CG	ASP	C	325	16.722	−6.108	2.200	1.00	79.91	C
ATOM	9904	OD1	ASP	C	325	15.468	−6.143	2.187	1.00	79.60	O
ATOM	9905	OD2	ASP	C	325	17.321	−6.040	1.095	1.00	79.90	O
ATOM	9906	C	ASP	C	325	17.019	−5.779	6.016	1.00	80.19	C
ATOM	9907	O	ASP	C	325	16.120	−6.397	6.603	1.00	80.11	O
ATOM	9909	N	TYR	C	326	18.192	−5.477	6.578	1.00	80.58	N
ATOM	9910	CA	TYR	C	326	18.494	−5.820	7.986	1.00	80.89	C
ATOM	9912	CB	TYR	C	326	19.780	−5.127	8.424	1.00	81.17	C
ATOM	9915	CG	TYR	C	326	20.129	−5.348	9.861	1.00	81.76	C
ATOM	9916	CD1	TYR	C	326	20.414	−6.632	10.339	1.00	82.98	C
ATOM	9918	CE1	TYR	C	326	20.742	−6.857	11.696	1.00	82.86	C
ATOM	9920	CZ	TYR	C	326	20.786	−5.773	12.576	1.00	82.65	C
ATOM	9921	OH	TYR	C	326	21.110	−5.955	13.897	1.00	82.36	O
ATOM	9923	CE2	TYR	C	326	20.501	−4.486	12.116	1.00	83.06	C
ATOM	9925	CD2	TYR	C	326	20.171	−4.282	10.763	1.00	83.08	C
ATOM	9927	C	TYR	C	326	17.346	−5.487	8.962	1.00	80.83	C
ATOM	9928	O	TYR	C	326	16.886	−6.353	9.691	1.00	80.90	O
ATOM	9930	N	LEU	C	327	16.865	−4.248	8.899	1.00	80.99	N
ATOM	9931	CA	LEU	C	327	15.818	−3.747	9.790	1.00	80.99	C
ATOM	9933	CB	LEU	C	327	15.716	−2.224	9.710	1.00	80.94	C
ATOM	9936	CG	LEU	C	327	16.940	−1.388	10.066	1.00	80.79	C
ATOM	9938	CD1	LEU	C	327	16.554	0.115	9.947	1.00	80.32	C
ATOM	9942	CD2	LEU	C	327	17.565	−1.734	11.426	1.00	79.34	C
ATOM	9946	C	LEU	C	327	14.425	−4.301	9.564	1.00	81.13	C
ATOM	9947	O	LEU	C	327	13.681	−4.459	10.525	1.00	81.44	O
ATOM	9949	N	ARG	C	328	14.048	−4.549	8.314	1.00	81.25	N
ATOM	9950	CA	ARG	C	328	12.784	−5.263	8.019	1.00	81.26	C
ATOM	9952	CB	ARG	C	328	12.502	−5.295	6.508	1.00	81.52	C
ATOM	9955	CG	ARG	C	328	12.184	−3.983	5.867	1.00	81.59	C
ATOM	9958	CD	ARG	C	328	12.262	−4.028	4.326	1.00	81.90	C
ATOM	9961	NE	ARG	C	328	11.474	−2.945	3.734	1.00	82.65	N
ATOM	9963	CZ	ARG	C	328	11.581	−2.467	2.493	1.00	83.03	C
ATOM	9964	NH1	ARG	C	328	12.429	−2.992	1.604	1.00	84.29	N
ATOM	9967	NH2	ARG	C	328	10.793	−1.449	2.127	1.00	82.82	N
ATOM	9970	C	ARG	C	328	12.744	−6.722	8.537	1.00	80.91	C
ATOM	9971	O	ARG	C	328	11.656	−7.248	8.754	1.00	80.39	O
ATOM	9973	N	GLU	C	329	13.918	−7.350	8.701	1.00	80.81	N
ATOM	9974	CA	GLU	C	329	14.063	−8.790	8.965	1.00	80.82	C
ATOM	9976	CB	GLU	C	329	14.887	−9.419	7.812	1.00	80.80	C
ATOM	9979	CG	GLU	C	329	14.088	−9.542	6.498	1.00	81.37	C
ATOM	9982	CD	GLU	C	329	14.928	−9.587	5.207	1.00	81.66	C
ATOM	9983	OE1	GLU	C	329	15.730	−8.671	4.942	1.00	82.08	O
ATOM	9984	OE2	GLU	C	329	14.764	−10.539	4.406	1.00	84.53	O
ATOM	9985	C	GLU	C	329	14.628	−9.163	10.372	1.00	80.55	C
ATOM	9986	O	GLU	C	329	14.541	−10.332	10.772	1.00	80.06	O
ATOM	9988	N	CYS	C	330	15.155	−8.188	11.129	1.00	80.37	N
ATOM	9989	CA	CYS	C	330	15.718	−8.442	12.488	1.00	80.24	C
ATOM	9991	CB	CYS	C	330	16.596	−7.274	12.948	1.00	80.30	C
ATOM	9994	SG	CYS	C	330	15.644	−5.808	13.446	1.00	81.52	S
ATOM	9996	C	CYS	C	330	14.676	−8.663	13.589	1.00	79.48	C
ATOM	9997	O	CYS	C	330	13.488	−8.409	13.401	1.00	79.59	O
ATOM	9999	N	ASN	C	331	15.168	−9.104	14.749	1.00	78.73	N
ATOM	10000	CA	ASN	C	331	14.391	−9.184	16.008	1.00	77.75	C
ATOM	10002	CB	ASN	C	331	14.915	−10.353	16.899	1.00	77.66	C
ATOM	10005	CG	ASN	C	331	14.625	−10.167	18.386	1.00	77.54	C
ATOM	10006	OD1	ASN	C	331	15.512	−10.333	9.220	1.00	77.10	O
ATOM	10007	ND2	ASN	C	331	13.391	−9.817	18.720	1.00	77.59	N
ATOM	10010	C	ASN	C	331	14.448	−7.796	16.691	1.00	77.16	C
ATOM	10011	O	ASN	C	331	15.529	−7.347	17.117	1.00	76.53	O
ATOM	10013	N	ARG	C	332	13.284	−7.142	16.796	1.00	76.69	N
ATOM	10014	CA	ARG	C	332	13.203	−5.711	17.226	1.00	76.31	C
ATOM	10016	CB	ARG	C	332	11.859	−5.081	16.828	1.00	75.91	C
ATOM	10019	CG	ARG	C	332	11.649	−4.872	15.325	1.00	75.57	C
ATOM	10022	CD	ARG	C	332	10.316	−4.214	15.008	1.00	74.80	C
ATOM	10025	NE	ARG	C	332	9.983	−4.122	13.586	1.00	73.35	N
ATOM	10027	CZ	ARG	C	332	8.838	−3.614	13.084	1.00	71.59	C
ATOM	10028	NH1	ARG	C	332	7.871	−3.132	13.873	1.00	69.71	N
ATOM	10031	NH2	ARG	C	332	8.655	−3.578	11.764	1.00	72.20	N
ATOM	10034	C	ARG	C	332	13.450	−5.468	18.724	1.00	76.10	C
ATOM	10035	O	ARG	C	332	13.802	−4.362	19.115	1.00	75.59	O
ATOM	10037	N	GLN	C	333	13.277	−6.502	19.547	1.00	76.33	N
ATOM	10038	CA	GLN	C	333	13.566	−6.418	20.996	1.00	76.44	C
ATOM	10040	CB	GLN	C	333	13.025	−7.623	21.833	1.00	76.35	C
ATOM	10043	CG	GLN	C	333	11.688	−8.350	21.423	1.00	75.65	C
ATOM	10046	CD	GLN	C	333	10.584	−7.486	20.776	1.00	74.62	C
ATOM	10047	OE1	GLN	C	333	10.422	−6.299	21.073	1.00	72.82	O
ATOM	10048	NE2	GLN	C	333	9.822	−8.111	19.889	1.00	74.15	N
ATOM	10051	C	GLN	C	333	15.087	−6.269	21.203	1.00	76.50	C
ATOM	10052	O	GLN	C	333	15.529	−5.465	22.034	1.00	76.59	O
ATOM	10054	N	GLU	C	334	15.862	−7.050	20.442	1.00	76.41	N
ATOM	10055	CA	GLU	C	334	17.320	−6.913	20.396	1.00	76.20	C
ATOM	10057	CB	GLU	C	334	17.939	−8.078	19.623	1.00	76.25	C
ATOM	10060	CG	GLU	C	334	19.451	−8.183	19.705	1.00	76.71	C
ATOM	10063	CD	GLU	C	334	20.020	−9.130	18.658	1.00	76.69	C
ATOM	10064	OE1	GLU	C	334	19.728	−10.345	18.756	1.00	77.74	O
ATOM	10065	OE2	GLU	C	334	20.754	−8.664	17.747	1.00	76.51	O
ATOM	10066	C	GLU	C	334	17.712	−5.560	19.781	1.00	75.98	C
ATOM	10067	O	GLU	C	334	18.501	−4.824	20.381	1.00	76.15	O
ATOM	10069	N	VAL	C	335	17.130	−5.215	18.629	1.00	75.62	N
ATOM	10070	CA	VAL	C	335	17.397	−3.915	17.952	1.00	75.32	C
ATOM	10072	CB	VAL	C	335	17.297	−4.066	16.375	1.00	75.27	C
ATOM	10074	CG1	VAL	C	335	17.718	−2.807	15.658	1.00	75.23	C
ATOM	10078	CG2	VAL	C	335	18.180	−5.229	15.866	1.00	75.52	C
ATOM	10082	C	VAL	C	335	16.482	−2.791	18.547	1.00	75.06	C
ATOM	10083	O	VAL	C	335	15.638	−2.212	17.867	1.00	75.10	O
ATOM	10085	N	ASN	C	336	16.674	−2.490	19.832	1.00	74.73	N
ATOM	10086	CA	ASN	C	336	15.763	−1.607	20.611	1.00	74.22	C
ATOM	10088	CE	ASN	C	336	15.884	−1.893	22.138	1.00	74.35	C
ATOM	10091	CG	ASN	C	336	17.267	−1.521	22.738	1.00	75.94	C
ATOM	10092	OD1	ASN	C	336	17.971	−0.647	22.236	1.00	79.80	O
ATOM	10093	ND2	ASN	C	336	17.647	−2.203	23.820	1.00	78.06	N
ATOM	10096	C	ASN	C	336	15.973	−0.123	20.314	1.00	73.19	C
ATOM	10097	O	ASN	C	336	16.865	0.224	19.570	1.00	72.58	O
ATOM	10099	N	ALA	C	337	15.186	0.734	20.956	1.00	72.76	N
ATOM	10100	CA	ALA	C	337	15.293	2.203	20.813	1.00	73.06	C
ATOM	10102	CB	ALA	C	337	14.387	2.911	21.840	1.00	72.88	C
ATOM	10106	C	ALA	C	337	16.707	2.766	20.913	1.00	72.75	C
ATOM	10107	O	ALA	C	337	17.073	3.670	20.148	1.00	72.35	O
ATOM	10109	N	VAL	C	338	17.480	2.210	21.847	1.00	72.56	N
ATOM	10110	CA	VAL	C	338	18.890	2.591	22.063	1.00	72.58	C
ATOM	10112	CE	VAL	C	338	19.493	1.957	23.383	1.00	72.88	C
ATOM	10114	CG1	VAL	C	338	20.966	2.362	23.575	1.00	73.53	C
ATOM	10118	CG2	VAL	C	338	18.665	2.365	24.613	1.00	73.40	C
ATOM	10122	C	VAL	C	338	19.802	2.245	20.859	1.00	72.27	C
ATOM	10123	O	VAL	C	338	20.727	3.014	20.548	1.00	71.86	O
ATOM	10125	N	VAL	C	339	19.529	1.110	20.200	1.00	71.90	N
ATOM	10126	CA	VAL	C	339	20.356	0.604	19.082	1.00	71.33	C
ATOM	10128	CE	VAL	C	339	20.026	−0.892	18.716	1.00	71.06	C
ATOM	10130	CG1	VAL	C	339	20.961	−1.414	17.614	1.00	71.19	C
ATOM	10134	CG2	VAL	C	339	20.111	−1.808	19.923	1.00	70.45	C
ATOM	10138	C	VAL	C	339	20.169	1.534	17.857	1.00	71.09	C
ATOM	10139	O	VAL	C	339	21.152	2.029	17.296	1.00	70.89	O
ATOM	10141	N	LEU	C	340	18.906	1.790	17.492	1.00	70.69	N
ATOM	10142	CA	LEU	C	340	18.519	2.804	16.472	1.00	70.43	C
ATOM	10144	CE	LEU	C	340	16.995	2.970	16.406	1.00	70.31	C
ATOM	10147	CG	LEU	C	340	16.056	1.753	16.257	1.00	69.85	C
ATOM	10149	CD1	LEU	C	340	14.685	2.196	15.764	1.00	69.59	C
ATOM	10153	CD2	LEU	C	340	16.609	0.664	15.349	1.00	68.71	C
ATOM	10157	C	LEU	C	340	19.129	4.184	16.726	1.00	70.14	C
ATOM	10158	O	LEU	C	340	19.513	4.877	15.801	1.00	70.05	O
ATOM	10160	N	LEU	C	341	19.214	4.551	17.999	1.00	70.16	N
ATOM	10161	CA	LEU	C	341	19.878	5.783	18.433	1.00	70.26	C
ATOM	10163	CE	LEU	C	341	19.663	6.006	19.937	1.00	70.28	C
ATOM	10166	CG	LEU	C	341	19.355	7.363	20.574	1.00	70.49	C
ATOM	10168	CD1	LEU	C	341	18.625	8.345	19.687	1.00	70.21	C
ATOM	10172	CD2	LEU	C	341	18.556	7.138	21.884	1.00	70.41	C
ATOM	10176	C	LEU	C	341	21.358	5.748	18.127	1.00	70.36	C
ATOM	10177	O	LEU	C	341	21.909	6.762	17.709	1.00	70.74	O
ATOM	10179	N	TYR	C	342	21.981	4.581	18.337	1.00	70.76	N
ATOM	10180	CA	TYR	C	342	23.438	4.360	18.135	1.00	70.71	C
ATOM	10182	CE	TYR	C	342	23.887	3.049	18.842	1.00	70.78	C
ATOM	10185	CG	TYR	C	342	25.372	2.652	18.725	1.00	71.23	C
ATOM	10186	CD1	TYR	C	342	26.417	3.570	19.031	1.00	71.51	C
ATOM	10188	CE1	TYR	C	342	27.794	3.201	18.909	1.00	70.48	C
ATOM	10190	CZ	TYR	C	342	28.124	1.903	18.498	1.00	71.24	C
ATOM	10191	OH	TYR	C	342	29.446	1.519	18.373	1.00	70.81	O
ATOM	10193	CE2	TYR	C	342	27.112	0.974	18.202	1.00	71.30	C
ATOM	10195	CD2	TYR	C	342	25.743	1.343	18.323	1.00	70.62	C
ATOM	10197	C	TYR	C	342	23.792	4.358	16.646	1.00	70.80	C
ATOM	10198	O	TYR	C	342	24.716	5.074	16.215	1.00	70.45	O
ATOM	10200	N	MET	C	343	23.021	3.587	15.870	1.00	70.97	N
ATOM	10201	CA	MET	C	343	23.162	3.515	14.390	1.00	70.93	C
ATOM	10203	CE	MET	C	343	22.140	2.545	13.770	1.00	70.47	C
ATOM	10206	CG	MET	C	343	22.282	1.068	14.308	1.00	71.90	C
ATOM	10209	SD	MET	C	343	21.151	−0.272	13.701	1.00	72.79	S
ATOM	10210	CE	MET	C	343	19.689	0.704	13.188	1.00	72.30	C
ATOM	10214	C	MET	C	343	23.047	4.912	13.780	1.00	70.21	C
ATOM	10215	O	MET	C	343	23.850	5.283	12.959	1.00	70.22	O
ATOM	10217	N	ALA	C	344	22.092	5.701	14.255	1.00	70.12	N
ATOM	10218	CA	ALA	C	344	21.969	7.125	13.886	1.00	70.11	C
ATOM	10220	CB	ALA	C	344	20.672	7.692	14.444	1.00	70.28	C
ATOM	10224	C	ALA	C	344	23.131	8.006	14.318	1.00	69.84	C
ATOM	10225	O	ALA	C	344	23.493	8.930	13.616	1.00	69.08	O
ATOM	10227	N	THR	C	345	23.691	7.738	15.485	1.00	70.52	N
ATOM	10228	CA	THR	C	345	24.843	8.521	15.972	1.00	71.46	C
ATOM	10230	CB	THR	C	345	25.074	8.262	17.470	1.00	71.52	C
ATOM	10232	OG1	THR	C	345	23.839	8.468	18.174	1.00	71.80	O
ATOM	10234	CG2	THR	C	345	26.024	9.311	18.080	1.00	71.23	C
ATOM	10238	C	THR	C	345	26.133	8.289	15.159	1.00	71.79	C
ATOM	10239	O	THR	C	345	26.860	9.237	14.857	1.00	71.96	O
ATOM	10241	N	GLN	C	346	26.382	7.034	14.801	1.00	72.01	N
ATOM	10242	CA	GLN	C	346	27.511	6.654	13.944	1.00	72.36	C
ATOM	10244	CB	GLN	C	346	27.539	5.134	13.830	1.00	72.56	C
ATOM	10247	CG	GLN	C	346	27.932	4.469	15.128	1.00	73.45	C
ATOM	10250	CD	GLN	C	346	27.904	2.990	15.014	1.00	73.76	C
ATOM	10251	OE1	GLN	C	346	28.916	2.387	14.674	1.00	73.65	O
ATOM	10252	NE2	GLN	C	346	26.740	2.394	15.236	1.00	73.05	N
ATOM	10255	C	GLN	C	346	27.494	7.278	12.523	1.00	72.65	C
ATOM	10256	O	GLN	C	346	28.533	7.702	11.971	1.00	72.77	O
ATOM	10258	N	ILE	C	347	26.304	7.328	11.944	1.00	72.39	N
ATOM	10259	CA	ILE	C	347	26.118	7.905	10.630	1.00	72.43	C
ATOM	10261	CB	ILE	C	347	24.815	7.336	9.978	1.00	72.24	C
ATOM	10263	CG1	ILE	C	347	25.001	5.817	9.826	1.00	72.40	C
ATOM	10266	CD1	ILE	C	347	23.817	5.074	9.312	1.00	73.30	C
ATOM	10270	CG2	ILE	C	347	24.541	7.954	8.594	1.00	71.56	C
ATOM	10274	C	ILE	C	347	26.226	9.449	10.694	1.00	72.26	C
ATOM	10275	O	ILE	C	347	26.833	10.028	9.806	1.00	72.44	O
ATOM	10277	N	SER	C	348	25.714	10.093	11.747	1.00	72.15	N
ATOM	10278	CA	SER	C	348	25.851	11.560	11.911	1.00	72.19	C
ATOM	10280	CB	SER	C	348	24.971	12.077	13.075	1.00	72.10	C
ATOM	10283	OG	SER	C	348	25.368	11.574	14.344	1.00	71.81	O
ATOM	10285	C	SER	C	348	27.328	12.074	12.043	1.00	72.34	C
ATOM	10286	O	SER	C	348	27.621	13.241	11.687	1.00	72.39	O
ATOM	10288	N	SER	C	349	28.236	11.208	12.517	1.00	72.20	N
ATOM	10289	CA	SER	C	349	29.665	11.549	12.701	1.00	72.36	C
ATOM	10291	CB	SER	C	349	30.323	10.638	13.752	1.00	72.44	C
ATOM	10294	OG	SER	C	349	30.655	9.362	13.232	1.00	72.96	O
ATOM	10296	C	SER	C	349	30.458	11.471	11.399	1.00	72.29	C
ATOM	10297	O	SER	C	349	31.247	12.367	11.102	1.00	72.14	O
ATOM	10299	N	ALA	C	350	30.270	10.376	10.657	1.00	72.27	N
ATOM	10300	CA	ALA	C	350	30.787	10.254	9.283	1.00	72.61	C
ATOM	10302	CB	ALA	C	350	30.339	8.953	8.643	1.00	72.71	C
ATOM	10306	C	ALA	C	350	30.335	11.422	8.419	1.00	72.60	C
ATOM	10307	O	ALA	C	350	31.152	12.036	7.743	1.00	72.58	O
ATOM	10309	N	MET	C	351	29.041	11.741	8.483	1.00	72.70	N
ATOM	10310	CA	MET	C	351	28.504	12.923	7.797	1.00	72.96	C
ATOM	10312	CB	MET	C	351	26.968	12.955	7.806	1.00	73.10	C
ATOM	10315	CG	MET	C	351	26.247	11.814	7.071	1.00	73.38	C
ATOM	10318	SD	MET	C	351	26.945	11.372	5.455	1.00	75.16	S
ATOM	10319	CE	MET	C	351	26.928	12.955	4.573	1.00	75.75	C
ATOM	10323	C	MET	C	351	29.044	14.251	8.307	1.00	72.97	C
ATOM	10324	O	MET	C	351	29.214	15.163	7.505	1.00	73.31	O
ATOM	10326	N	GLU	C	352	29.312	14.375	9.607	1.00	72.98	N
ATOM	10327	CA	GLU	C	352	30.055	15.544	10.107	1.00	72.93	C
ATOM	10329	CB	GLU	C	352	30.152	15.584	11.647	1.00	73.13	C
ATOM	10332	CG	GLU	C	352	31.057	16.710	12.172	1.00	72.88	C
ATOM	10335	CD	GLU	C	352	30.852	17.082	13.616	1.00	73.46	C
ATOM	10336	OE1	GLU	C	352	30.371	16.263	14.423	1.00	75.64	O
ATOM	10337	OE2	GLU	C	352	31.207	18.224	13.954	1.00	75.68	O
ATOM	10338	C	GLU	C	352	31.464	15.615	9.510	1.00	72.87	C
ATOM	10339	O	GLU	C	352	31.947	16.732	9.244	1.00	72.91	O
ATOM	10341	N	TYR	C	353	32.117	14.449	9.336	1.00	72.62	N
ATOM	10342	CA	TYR	C	353	33.496	14.382	8.790	1.00	72.32	C
ATOM	10344	CB	TYR	C	353	34.094	12.973	8.912	1.00	72.24	C
ATOM	10347	CG	TYR	C	353	35.396	12.801	8.154	1.00	72.49	C
ATOM	10348	CD1	TYR	C	353	36.608	13.294	8.670	1.00	72.59	C
ATOM	10350	CE1	TYR	C	353	37.818	13.140	7.976	1.00	72.54	C
ATOM	10352	CZ	TYR	C	353	37.814	12.499	6.733	1.00	73.30	C
ATOM	10353	OH	TYR	C	353	38.986	12.324	6.016	1.00	72.72	O
ATOM	10355	CE2	TYR	C	353	36.614	12.007	6.204	1.00	73.19	C
ATOM	10357	CD2	TYR	C	353	35.418	12.168	6.914	1.00	72.62	C
ATOM	10359	C	TYR	C	353	33.555	14.862	7.338	1.00	71.93	C
ATOM	10360	O	TYR	C	353	34.338	15.753	7.008	1.00	71.48	O
ATOM	10362	N	LEU	C	354	32.715	14.255	6.497	1.00	71.67	N
ATOM	10363	CA	LEU	C	354	32.591	14.624	5.094	1.00	71.36	C
ATOM	10365	CB	LEU	C	354	31.526	13.777	4.410	1.00	70.90	C
ATOM	10368	CG	LEU	C	354	31.820	12.279	4.253	1.00	70.54	C
ATOM	10370	CD1	LEU	C	354	30.573	11.504	3.917	1.00	68.88	C
ATOM	10374	CD2	LEU	C	354	32.848	12.013	3.183	1.00	71.21	C
ATOM	10378	C	LEU	C	354	32.273	16.113	4.935	1.00	71.44	C
ATOM	10379	O	LEU	C	354	32.910	16.789	4.129	1.00	71.35	O
ATOM	10381	N	GLU	C	355	31.329	16.614	5.730	1.00	71.78	N
ATOM	10382	CA	GLU	C	355	30.929	18.043	5.708	1.00	72.31	C
ATOM	10384	CB	GLU	C	355	29.827	18.307	6.747	1.00	72.29	C
ATOM	10387	CG	GLU	C	355	29.172	19.691	6.685	1.00	72.38	C
ATOM	10390	CD	GLU	C	355	28.545	20.086	8.015	1.00	73.12	C
ATOM	10391	OE1	GLU	C	355	29.304	20.313	8.990	1.00	75.54	O
ATOM	10392	OE2	GLU	C	355	27.305	20.165	8.093	1.00	72.31	O
ATOM	10393	C	GLU	C	355	32.115	19.007	5.942	1.00	72.72	C
ATOM	10394	O	GLU	C	355	32.291	19.999	5.219	1.00	72.01	O
ATOM	10396	N	LYS	C	356	32.908	18.685	6.963	1.00	73.41	N
ATOM	10397	CA	LYS	C	356	34.162	19.383	7.264	1.00	73.76	C
ATOM	10399	CB	LYS	C	356	34.844	18.757	8.495	1.00	73.70	C
ATOM	10402	CG	LYS	C	356	35.861	19.656	9.159	1.00	74.42	C
ATOM	10405	CD	LYS	C	356	36.885	18.875	10.002	1.00	74.54	C
ATOM	10408	CE	LYS	C	356	38.243	19.608	10.103	1.00	74.52	C
ATOM	10411	NZ	LYS	C	356	39.325	18.699	10.610	1.00	74.51	N
ATOM	10415	C	LYS	C	356	35.105	19.387	6.043	1.00	73.73	C
ATOM	10416	O	LYS	C	356	35.679	20.430	5.728	1.00	73.92	O
ATOM	10418	N	LYS	C	357	35.204	18.244	5.344	1.00	73.81	N
ATOM	10419	CA	LYS	C	357	36.031	18.095	4.109	1.00	73.75	C
ATOM	10421	CB	LYS	C	357	36.407	16.609	3.882	1.00	73.68	C
ATOM	10424	CG	LYS	C	357	37.355	15.991	4.901	1.00	73.75	C
ATOM	10427	CD	LYS	C	357	38.412	15.095	4.208	1.00	75.02	C
ATOM	10430	CE	LYS	C	357	39.583	15.925	3.544	1.00	75.77	C
ATOM	10433	NZ	LYS	C	357	40.144	15.386	2.221	1.00	74.30	N
ATOM	10437	C	LYS	C	357	35.431	18.676	2.785	1.00	73.60	C
ATOM	10438	O	LYS	C	357	36.046	18.553	1.718	1.00	73.29	O
ATOM	10440	N	ASN	C	358	34.262	19.309	2.859	1.00	73.62	N
ATOM	10441	CA	ASN	C	358	33.518	19.796	1.689	1.00	73.61	C
ATOM	10443	CB	ASN	C	358	34.198	21.059	1.114	1.00	73.51	C
ATOM	10446	CG	ASN	C	358	33.189	22.118	0.630	1.00	73.98	C
ATOM	10447	OD1	ASN	C	358	32.285	22.523	1.366	1.00	73.68	O
ATOM	10448	ND2	ASN	C	358	33.361	22.583	−0.606	1.00	74.99	N
ATOM	10451	C	ASN	C	358	33.223	18.711	0.622	1.00	73.66	C
ATOM	10452	O	ASN	C	358	33.336	18.966	−0.576	1.00	73.82	O
ATOM	10454	N	PHE	C	359	32.846	17.507	1.097	1.00	73.84	N
ATOM	10455	CA	PHE	C	359	32.330	16.385	0.269	1.00	73.50	C
ATOM	10457	CB	PHE	C	359	32.934	15.039	0.691	1.00	74.08	C
ATOM	10460	CG	PHE	C	359	34.325	14.844	0.215	1.00	74.97	C
ATOM	10461	CD1	PHE	C	359	35.358	15.531	0.823	1.00	76.55	C
ATOM	10463	CE1	PHE	C	359	36.685	15.383	0.390	1.00	76.77	C
ATOM	10465	CZ	PHE	C	359	36.975	14.541	−0.691	1.00	76.55	C
ATOM	10467	CE2	PHE	C	359	35.942	13.847	−1.317	1.00	77.48	C
ATOM	10469	CD2	PHE	C	359	34.616	13.997	−0.855	1.00	77.20	C
ATOM	10471	C	PHE	C	359	30.816	16.241	0.371	1.00	72.79	C
ATOM	10472	O	PHE	C	359	30.250	16.539	1.430	1.00	73.12	O
ATOM	10474	N	ILE	C	360	30.191	15.789	−0.733	1.00	71.60	N
ATOM	10475	CA	ILE	C	360	28.814	15.278	−0.781	1.00	70.28	C
ATOM	10477	CB	ILE	C	360	28.011	15.872	−1.958	1.00	70.65	C
ATOM	10479	CG1	ILE	C	360	28.187	17.361	−2.091	1.00	70.74	C
ATOM	10482	CD1	ILE	C	360	27.859	18.118	−0.801	1.00	71.56	C
ATOM	10486	CG2	ILE	C	360	26.498	15.586	−1.750	1.00	73.25	C
ATOM	10490	C	ILE	C	360	28.853	13.782	−1.011	1.00	68.87	C
ATOM	10491	O	ILE	C	360	29.685	13.310	−1.769	1.00	68.78	O
ATOM	10493	N	HIS	C	361	27.920	13.052	−0.412	1.00	67.13	N
ATOM	10494	CA	HIS	C	361	27.726	11.631	−0.711	1.00	65.94	C
ATOM	10496	CB	HIS	C	361	27.259	10.873	0.529	1.00	65.39	C
ATOM	10499	CG	HIS	C	361	27.172	9.399	0.342	1.00	62.87	C
ATOM	10500	ND1	HIS	C	361	26.174	8.802	−0.393	1.00	62.74	N
ATOM	10502	CE1	HIS	C	361	26.344	7.497	−0.396	1.00	62.57	C
ATOM	10504	NE2	HIS	C	361	27.410	7.225	0.328	1.00	62.24	N
ATOM	10506	CD2	HIS	C	361	27.952	8.400	0.792	1.00	61.19	C
ATOM	10508	C	HIS	C	361	26.725	11.419	−1.832	1.00	65.91	C
ATOM	10509	O	HIS	C	361	26.912	10.526	−2.648	1.00	65.95	O
ATOM	10511	N	ARG	C	362	25.610	12.151	−1.799	1.00	65.73	N
ATOM	10512	CA	ARG	C	362	24.551	12.109	−2.852	1.00	65.41	C
ATOM	10514	CB	ARG	C	362	25.102	12.519	−4.242	1.00	65.29	C
ATOM	10517	CG	ARG	C	362	25.276	14.025	−4.434	1.00	64.75	C
ATOM	10520	CD	ARG	C	362	25.170	14.478	−5.830	1.00	64.51	C
ATOM	10523	NE	ARG	C	362	26.181	13.800	−6.623	1.00	63.60	N
ATOM	10525	CZ	ARG	C	362	26.090	13.564	−7.919	1.00	65.57	C
ATOM	10526	NH1	ARG	C	362	25.044	13.989	−8.636	1.00	65.63	N
ATOM	10529	NH2	ARG	C	362	27.079	12.909	−8.529	1.00	66.33	N
ATOM	10532	C	ARG	C	362	23.716	10.841	−2.982	1.00	65.05	C
ATOM	10533	O	ARG	C	362	22.864	10.770	−3.837	1.00	64.64	O
ATOM	10535	N	ASP	C	363	23.916	9.859	−2.122	1.00	66.16	N
ATOM	10536	CA	ASP	C	363	23.138	8.580	−2.178	1.00	66.80	C
ATOM	10538	CB	ASP	C	363	23.724	7.584	−3.209	1.00	67.10	C
ATOM	10541	CG	ASP	C	363	22.657	6.736	−3.891	1.00	67.76	C
ATOM	10542	OD1	ASP	C	363	21.472	7.119	−3.971	1.00	69.17	O
ATOM	10543	OD2	ASP	C	363	22.937	5.648	−4.402	1.00	73.12	O
ATOM	10544	C	ASP	C	363	22.960	7.926	−0.825	1.00	66.80	C
ATOM	10545	O	ASP	C	363	22.964	6.712	−0.691	1.00	67.07	O
ATOM	10547	N	LEU	C	364	22.700	8.779	0.150	1.00	67.11	N
ATOM	10548	CA	LEU	C	364	22.548	8.401	1.528	1.00	67.33	C
ATOM	10550	CB	LEU	C	364	22.754	9.631	2.383	1.00	67.25	C
ATOM	10553	CG	LEU	C	364	22.844	9.456	3.874	1.00	68.89	C
ATOM	10555	CD1	LEU	C	364	24.041	8.596	4.243	1.00	69.80	C
ATOM	10559	CD2	LEU	C	364	22.929	10.869	4.506	1.00	68.61	C
ATOM	10563	C	LEU	C	364	21.144	7.808	1.729	1.00	66.91	C
ATOM	10564	O	LEU	C	364	20.124	8.484	1.554	1.00	67.30	O
ATOM	10566	N	ALA	C	365	21.115	6.531	2.070	1.00	66.28	N
ATOM	10567	CA	ALA	C	365	19.890	5.777	2.236	1.00	65.79	C
ATOM	10569	CB	ALA	C	365	19.366	5.381	0.892	1.00	65.60	C
ATOM	10573	C	ALA	C	365	20.212	4.541	3.073	1.00	65.63	C
ATOM	10574	O	ALA	C	365	21.365	4.140	3.175	1.00	65.09	O
ATOM	10576	N	ALA	C	366	19.191	3.955	3.679	1.00	66.17	N
ATOM	10577	CA	ALA	C	366	19.353	2.743	4.498	1.00	66.60	C
ATOM	10579	CB	ALA	C	366	18.080	2.387	5.214	1.00	66.17	C
ATOM	10583	C	ALA	C	366	19.820	1.582	3.629	1.00	67.39	C
ATOM	10584	O	ALA	C	366	20.728	0.864	4.006	1.00	66.90	O
ATOM	10586	N	ARG	C	367	19.265	1.461	2.429	1.00	68.85	N
ATOM	10587	CA	ARG	C	367	19.756	0.458	1.457	1.00	70.33	C
ATOM	10589	CB	ARG	C	367	18.864	0.397	0.178	1.00	70.25	C
ATOM	10592	CG	ARG	C	367	19.265	1.360	−0.917	1.00	70.79	C
ATOM	10595	CD	ARG	C	367	18.181	1.725	−1.920	1.00	71.07	C
ATOM	10598	NE	ARG	C	367	18.608	2.979	−2.535	1.00	70.84	N
ATOM	10600	CZ	ARG	C	367	18.080	4.191	−2.371	1.00	70.63	C
ATOM	10601	NH1	ARG	C	367	16.980	4.418	−1.668	1.00	70.61	N
ATOM	10604	NH2	ARG	C	367	18.660	5.223	−2.988	1.00	73.40	N
ATOM	10607	C	ARG	C	367	21.273	0.583	1.108	1.00	70.73	C
ATOM	10608	O	ARG	C	367	21.873	−0.421	0.677	1.00	70.95	O
ATOM	10610	N	ASN	C	368	21.843	1.797	1.286	1.00	71.08	N
ATOM	10611	CA	ASN	C	368	23.283	2.097	1.122	1.00	71.28	C
ATOM	10613	CB	ASN	C	368	23.455	3.417	0.334	1.00	71.74	C
ATOM	10616	CG	ASN	C	368	23.137	3.275	−1.149	1.00	73.25	C
ATOM	10617	OD1	ASN	C	368	23.290	2.201	−1.746	1.00	75.56	O
ATOM	10618	ND2	ASN	C	368	22.707	4.375	−1.760	1.00	74.86	N
ATOM	10621	C	ASN	C	368	24.130	2.159	2.408	1.00	71.83	C
ATOM	10622	O	ASN	C	368	25.313	2.532	2.356	1.00	71.11	O
ATOM	10624	N	CYS	C	369	23.562	1.766	3.549	1.00	72.84	N
ATOM	10625	CA	CYS	C	369	24.367	1.535	4.759	1.00	73.90	C
ATOM	10627	CB	CYS	C	369	23.640	2.028	5.973	1.00	74.12	C
ATOM	10630	SG	CYS	C	369	23.632	3.814	5.925	1.00	78.42	S
ATOM	10632	C	CYS	C	369	24.843	0.088	4.969	1.00	74.14	C
ATOM	10633	O	CYS	C	369	24.259	−0.877	4.468	1.00	73.66	O
ATOM	10635	N	LEU	C	370	25.943	−0.022	5.706	1.00	74.47	N
ATOM	10636	CA	LEU	C	370	26.578	−1.286	5.976	1.00	74.69	C
ATOM	10638	CB	LEU	C	370	27.912	−1.380	5.235	1.00	74.94	C
ATOM	10641	CG	LEU	C	370	27.828	−1.627	3.713	1.00	74.82	C
ATOM	10643	CD1	LEU	C	370	29.253	−1.663	3.119	1.00	75.15	C
ATOM	10647	CD2	LEU	C	370	27.085	−2.897	3.325	1.00	74.34	C
ATOM	10651	C	LEU	C	370	26.744	−1.451	7.471	1.00	74.91	C
ATOM	10652	O	LEU	C	370	27.175	−0.515	8.155	1.00	74.32	O
ATOM	10654	N	VAL	C	371	26.395	−2.658	7.944	1.00	75.51	N
ATOM	10655	CA	VAL	C	371	26.285	−3.003	9.358	1.00	75.78	C
ATOM	10657	CB	VAL	C	371	24.894	−3.598	9.672	1.00	75.87	C
ATOM	10659	CG1	VAL	C	371	24.737	−3.873	11.190	1.00	76.53	C
ATOM	10663	CG2	VAL	C	371	23.761	−2.682	9.164	1.00	76.14	C
ATOM	10667	C	VAL	C	371	27.345	−4.052	9.668	1.00	76.10	C
ATOM	10668	O	VAL	C	371	27.380	−5.104	9.017	1.00	75.96	O
ATOM	10670	N	GLY	C	372	28.216	−3.740	10.628	1.00	76.55	N
ATOM	10671	CA	GLY	C	372	29.107	−4.719	11.235	1.00	77.27	C
ATOM	10674	C	GLY	C	372	28.423	−5.477	12.380	1.00	77.98	C
ATOM	10675	O	GLY	C	372	27.396	−5.025	12.914	1.00	78.29	O
ATOM	10677	N	GLU	C	373	28.999	−6.620	12.773	1.00	78.31	N
ATOM	10678	CA	GLU	C	373	28.630	−7.290	14.025	1.00	78.90	C
ATOM	10680	CB	GLU	C	373	29.574	−8.460	14.335	1.00	79.37	C
ATOM	10683	CG	GLU	C	373	29.536	−9.627	13.339	1.00	80.54	C
ATOM	10686	CD	GLU	C	373	28.849	−10.904	13.837	1.00	81.77	C
ATOM	10687	OE1	GLU	C	373	28.742	−11.152	15.063	1.00	81.02	O
ATOM	10688	OE2	GLU	C	373	28.440	−11.707	12.965	1.00	83.70	O
ATOM	10689	C	GLU	C	373	28.703	−6.273	15.180	1.00	79.06	C
ATOM	10690	O	GLU	C	373	29.473	−5.293	15.102	1.00	79.11	O
ATOM	10692	N	ASN	C	374	27.887	−6.499	16.218	1.00	78.78	N
ATOM	10693	CA	ASN	C	374	27.778	−5.593	17.376	1.00	78.46	C
ATOM	10695	CB	ASN	C	374	29.088	−5.614	18.201	1.00	78.69	C
ATOM	10698	CG	ASN	C	374	29.434	−7.000	18.745	1.00	79.41	C
ATOM	10699	OD1	ASN	C	374	28.619	−7.924	18.715	1.00	80.93	O
ATOM	10700	ND2	ASN	C	374	30.638	−7.131	19.289	1.00	80.02	N
ATOM	10703	C	ASN	C	374	27.375	−4.158	17.009	1.00	77.73	C
ATOM	10704	O	ASN	C	374	27.845	−3.181	17.608	1.00	77.21	O
ATOM	10706	N	HIS	C	375	26.537	−4.045	15.981	1.00	77.30	N
ATOM	10707	CA	HIS	C	375	25.909	−2.782	15.588	1.00	77.05	C
ATOM	10709	CB	HIS	C	375	24.803	−2.437	16.595	1.00	77.01	C
ATOM	10712	CG	HIS	C	375	23.865	−3.576	16.838	1.00	77.05	C
ATOM	10713	ND1	HIS	C	375	23.476	−3.971	18.099	1.00	76.76	N
ATOM	10715	CE1	HIS	C	375	22.676	−5.019	18.003	1.00	77.09	C
ATOM	10717	NE2	HIS	C	375	22.547	−5.328	16.725	1.00	77.39	N
ATOM	10719	CD2	HIS	C	375	23.291	−4.449	15.976	1.00	77.16	C
ATOM	10721	C	HIS	C	375	26.854	−1.592	15.335	1.00	76.87	C
ATOM	10722	O	HIS	C	375	26.455	−0.434	15.512	1.00	77.07	O
ATOM	10724	N	LEU	C	376	28.089	−1.881	14.889	1.00	76.49	N
ATOM	10725	CA	LEU	C	376	28.924	−0.871	14.198	1.00	75.58	C
ATOM	10727	CB	LEU	C	376	30.389	−1.317	14.033	1.00	75.43	C
ATOM	10730	CG	LEU	C	376	31.433	−0.190	14.069	1.00	75.58	C
ATOM	10732	CD1	LEU	C	376	32.865	−0.754	14.175	1.00	75.63	C
ATOM	10736	CD2	LEU	C	376	31.320	0.730	12.864	1.00	75.97	C
ATOM	10740	C	LEU	C	376	28.247	−0.622	12.842	1.00	75.01	C
ATOM	10741	O	LEU	C	376	27.794	−1.570	12.197	1.00	74.60	O
ATOM	10743	N	VAL	C	377	28.130	0.645	12.450	1.00	74.55	N
ATOM	10744	CA	VAL	C	377	27.545	1.036	11.149	1.00	74.53	C
ATOM	10746	CB	VAL	C	377	26.158	1.697	11.350	1.00	74.35	C
ATOM	10748	CG1	VAL	C	377	25.383	1.752	10.052	1.00	74.07	C
ATOM	10752	CG2	VAL	C	377	25.353	0.911	12.363	1.00	74.99	C
ATOM	10756	C	VAL	C	377	28.491	1.980	10.366	1.00	74.29	C
ATOM	10757	O	VAL	C	377	29.067	2.905	10.957	1.00	74.83	O
ATOM	10759	N	LYS	C	378	28.673	1.728	9.061	1.00	73.71	N
ATOM	10760	CA	LYS	C	378	29.444	2.635	8.164	1.00	73.37	C
ATOM	10762	CB	LYS	C	378	30.814	2.062	7.770	1.00	72.70	C
ATOM	10765	CG	LYS	C	378	31.599	1.521	8.945	1.00	72.86	C
ATOM	10768	CD	LYS	C	378	33.097	1.644	8.812	1.00	72.42	C
ATOM	10771	CE	LYS	C	378	33.810	0.793	9.861	1.00	71.56	C
ATOM	10774	NZ	LYS	C	378	35.156	1.343	10.150	1.00	71.67	N
ATOM	10778	C	LYS	C	378	28.661	2.974	6.903	1.00	73.28	C
ATOM	10779	O	LYS	C	378	27.950	2.130	6.340	1.00	73.06	O
ATOM	10781	N	VAL	C	379	28.817	4.218	6.454	1.00	73.58	N
ATOM	10782	CA	VAL	C	379	28.185	4.692	5.226	1.00	73.90	C
ATOM	10784	CB	VAL	C	379	28.190	6.240	5.116	1.00	73.92	C
ATOM	10786	CG1	VAL	C	379	27.599	6.705	3.767	1.00	73.30	C
ATOM	10790	CG2	VAL	C	379	27.419	6.856	6.303	1.00	74.15	C
ATOM	10794	C	VAL	C	379	28.969	4.077	4.070	1.00	74.27	C
ATOM	10795	O	VAL	C	379	30.213	4.164	4.048	1.00	74.38	O
ATOM	10797	N	ALA	C	380	28.237	3.449	3.144	1.00	74.28	N
ATOM	10798	CA	ALA	C	380	28.809	2.844	1.946	1.00	74.06	C
ATOM	10800	CB	ALA	C	380	28.313	1.399	1.793	1.00	73.97	C
ATOM	10804	C	ALA	C	380	28.498	3.659	0.680	1.00	73.73	C
ATOM	10805	O	ALA	C	380	27.893	4.728	0.733	1.00	73.31	O
ATOM	10807	N	ASP	C	381	29.020	3.135	−0.429	1.00	73.47	N
ATOM	10808	CA	ASP	C	381	28.584	3.382	−1.796	1.00	72.91	C
ATOM	10810	CB	ASP	C	381	27.106	3.040	−2.002	1.00	73.22	C
ATOM	10813	CG	ASP	C	381	26.776	2.794	−3.467	1.00	74.76	C
ATOM	10814	OD1	ASP	C	381	27.282	3.542	−4.354	1.00	75.68	O
ATOM	10815	OD2	ASP	C	381	26.040	1.839	−3.818	1.00	77.52	O
ATOM	10816	C	ASP	C	381	28.879	4.766	−2.232	1.00	72.08	C
ATOM	10817	O	ASP	C	381	27.959	5.598	−2.326	1.00	72.39	O
ATOM	10819	N	PHE	C	382	30.156	5.004	−2.534	1.00	71.02	N
ATOM	10820	CA	PHE	C	382	30.617	6.353	−2.851	1.00	70.16	C
ATOM	10822	CB	PHE	C	382	31.970	6.601	−2.205	1.00	69.45	C
ATOM	10825	CG	PHE	C	382	31.903	6.582	−0.712	1.00	68.96	C
ATOM	10826	CD1	PHE	C	382	31.587	7.743	0.000	1.00	68.39	C
ATOM	10828	CE1	PHE	C	382	31.500	7.723	1.385	1.00	67.82	C
ATOM	10830	CZ	PHE	C	382	31.705	6.530	2.066	1.00	68.20	C
ATOM	10832	CE2	PHE	C	382	32.001	5.363	1.359	1.00	67.57	C
ATOM	10834	CD2	PHE	C	382	32.080	5.392	−0.008	1.00	68.35	C
ATOM	10836	C	PHE	C	382	30.559	6.713	−4.344	1.00	70.25	C
ATOM	10837	O	PHE	C	382	30.979	7.799	−4.717	1.00	70.36	O
ATOM	10839	N	GLY	C	383	29.954	5.846	−5.169	1.00	70.23	N
ATOM	10840	CA	GLY	C	383	29.744	6.062	−6.607	1.00	70.11	C
ATOM	10843	C	GLY	C	383	29.261	7.402	−7.128	1.00	70.15	C
ATOM	10844	O	GLY	C	383	29.461	7.684	−8.312	1.00	70.61	O
ATOM	10846	N	LEU	C	384	28.597	8.197	−6.281	1.00	69.98	N
ATOM	10847	CA	LEU	C	384	28.139	9.559	−6.625	1.00	69.89	C
ATOM	10849	CB	LEU	C	384	26.610	9.651	−6.474	1.00	69.79	C
ATOM	10852	CG	LEU	C	384	25.830	8.862	−7.506	1.00	69.31	C
ATOM	10854	CD1	LEU	C	384	24.400	8.774	−7.093	1.00	69.27	C
ATOM	10858	CD2	LEU	C	384	25.970	9.511	−8.880	1.00	70.35	C
ATOM	10862	C	LEU	C	384	28.762	10.639	−5.777	1.00	69.86	C
ATOM	10863	O	LEU	C	384	28.367	11.803	−5.878	1.00	69.99	O
ATOM	10865	N	SER	C	385	29.735	10.278	−4.953	1.00	69.52	N
ATOM	10866	CA	SER	C	385	30.379	11.250	−4.087	1.00	69.55	C
ATOM	10868	CB	SER	C	385	31.167	10.544	−3.006	1.00	69.26	C
ATOM	10871	OG	SER	C	385	30.332	9.564	−2.437	1.00	69.75	O
ATOM	10873	C	SER	C	385	31.267	12.203	−4.879	1.00	69.52	C
ATOM	10874	O	SER	C	385	31.755	11.854	−5.930	1.00	68.74	O
ATOM	10876	N	ARG	C	386	31.398	13.426	−4.379	1.00	70.34	N
ATOM	10877	CA	ARG	C	386	32.196	14.475	−4.999	1.00	71.15	C
ATOM	10879	CB	ARG	C	386	31.304	15.433	−5.794	1.00	71.46	C
ATOM	10882	CG	ARG	C	386	30.439	14.805	−6.875	1.00	72.73	C
ATOM	10885	CD	ARG	C	386	31.220	14.228	−8.046	1.00	74.32	C
ATOM	10888	NE	ARG	C	386	30.539	13.065	−8.607	1.00	74.51	N
ATOM	10890	CZ	ARG	C	386	30.572	12.689	−9.876	1.00	76.36	C
ATOM	10891	NH1	ARG	C	386	31.252	13.366	−10.800	1.00	79.35	N
ATOM	10894	NH2	ARG	C	386	29.883	11.616	−10.248	1.00	77.73	N
ATOM	10897	C	ARG	C	386	32.856	15.296	−3.927	1.00	71.72	C
ATOM	10898	O	ARG	C	386	32.207	15.587	−2.945	1.00	71.34	O
ATOM	10900	N	LEU	C	387	34.124	15.681	−4.128	1.00	73.15	N
ATOM	10901	CA	LEU	C	387	34.720	16.828	−3.416	1.00	73.54	C
ATOM	10903	CB	LEU	C	387	36.251	16.863	−3.510	1.00	73.60	C
ATOM	10906	CG	LEU	C	387	36.900	18.178	−2.998	1.00	73.83	C
ATOM	10908	CD1	LEU	C	387	36.768	18.339	−1.476	1.00	74.41	C
ATOM	10912	CD2	LEU	C	387	38.360	18.305	−3.433	1.00	73.71	C
ATOM	10916	C	LEU	C	387	34.174	18.079	−4.056	1.00	73.78	C
ATOM	10917	O	LEU	C	387	34.561	18.398	−5.170	1.00	74.01	O
ATOM	10919	N	MET	C	388	33.302	18.794	−3.361	1.00	74.42	N
ATOM	10920	CA	MET	C	388	32.767	20.044	−3.905	1.00	75.15	C
ATOM	10922	CB	MET	C	388	31.679	20.612	−3.017	1.00	75.17	C
ATOM	10925	CG	MET	C	388	30.451	19.808	−2.933	1.00	74.40	C
ATOM	10928	SD	MET	C	388	29.102	20.928	−2.553	1.00	75.17	S
ATOM	10929	CE	MET	C	388	29.417	21.270	−0.715	1.00	74.55	C
ATOM	10933	C	MET	C	388	33.827	21.135	−4.025	1.00	75.66	C
ATOM	10934	O	MET	C	388	34.751	21.177	−3.219	1.00	75.82	O
ATOM	10936	N	THR	C	389	33.654	22.017	−5.011	1.00	76.25	N
ATOM	10937	CA	THR	C	389	34.418	23.268	−5.117	1.00	76.88	C
ATOM	10939	CB	THR	C	389	35.008	23.414	−6.535	1.00	76.76	C
ATOM	10941	OG1	THR	C	389	35.764	22.243	−6.875	1.00	76.73	O
ATOM	10943	CG2	THR	C	389	36.018	24.535	−6.586	1.00	76.81	C
ATOM	10947	C	THR	C	389	33.472	24.416	−4.775	1.00	77.50	C
ATOM	10948	O	THR	C	389	33.001	25.140	−5.655	1.00	77.75	O
ATOM	10950	N	GLY	C	390	33.184	24.555	−3.483	1.00	78.25	N
ATOM	10951	CA	GLY	C	390	32.197	25.517	−2.975	1.00	78.69	C
ATOM	10954	C	GLY	C	390	30.979	24.790	−2.434	1.00	79.20	C
ATOM	10955	O	GLY	C	390	31.119	23.718	−1.829	1.00	79.08	O
ATOM	10957	N	ASP	C	391	29.789	25.348	−2.697	1.00	79.60	N
ATOM	10958	CA	ASP	C	391	28.526	24.998	−1.983	1.00	79.61	C
ATOM	10960	CB	ASP	C	391	28.034	26.214	−1.135	1.00	80.08	C
ATOM	10963	CG	ASP	C	391	27.940	27.537	−1.942	1.00	82.30	C
ATOM	10964	OD1	ASP	C	391	27.487	27.497	−3.131	1.00	85.80	O
ATOM	10965	OD2	ASP	C	391	28.318	28.658	−1.465	1.00	83.20	O
ATOM	10966	C	ASP	C	391	27.421	24.480	−2.922	1.00	79.02	C
ATOM	10967	O	ASP	C	391	26.227	24.621	−2.623	1.00	79.50	O
ATOM	10969	N	THR	C	392	27.819	23.860	−4.034	1.00	77.94	N
ATOM	10970	CA	THR	C	392	26.911	23.557	−5.138	1.00	77.36	C
ATOM	10972	CB	THR	C	392	26.555	24.870	−5.872	1.00	77.79	C
ATOM	10974	OG1	THR	C	392	25.635	25.633	−5.088	1.00	78.85	O
ATOM	10976	CG2	THR	C	392	25.765	24.645	−7.176	1.00	79.48	C
ATOM	10980	C	THR	C	392	27.638	22.630	−6.083	1.00	76.29	C
ATOM	10981	O	THR	C	392	28.693	23.010	−6.589	1.00	76.52	O
ATOM	10983	N	TYR	C	393	27.103	21.424	−6.287	1.00	74.87	N
ATOM	10984	CA	TYR	C	393	27.511	20.533	−7.385	1.00	73.85	C
ATOM	10986	CB	TYR	C	393	28.140	19.238	−6.894	1.00	73.35	C
ATOM	10989	CG	TYR	C	393	28.539	18.283	−8.026	1.00	74.10	C
ATOM	10990	CD1	TYR	C	393	27.597	17.374	−8.610	1.00	73.98	C
ATOM	10992	CE1	TYR	C	393	27.974	16.496	−9.669	1.00	73.05	C
ATOM	10994	CZ	TYR	C	393	29.308	16.514	−10.140	1.00	72.95	C
ATOM	10995	OH	TYR	C	393	29.723	15.674	−11.135	1.00	72.05	O
ATOM	10997	CE2	TYR	C	393	30.252	17.386	−9.578	1.00	73.02	C
ATOM	10999	CD2	TYR	C	393	29.865	18.267	−8.523	1.00	73.85	C
ATOM	11001	C	TYR	C	393	26.272	20.199	−8.191	1.00	73.27	C
ATOM	11002	O	TYR	C	393	25.302	19.655	−7.643	1.00	73.14	O
ATOM	11004	N	THR	C	394	26.352	20.452	−9.498	1.00	72.58	N
ATOM	11005	CA	THR	C	394	25.208	20.425	−10.387	1.00	71.86	C
ATOM	11007	CB	THR	C	394	25.176	21.689	−11.259	1.00	71.93	C
ATOM	11009	OG1	THR	C	394	25.353	22.860	−10.442	1.00	70.42	O
ATOM	11011	CG2	THR	C	394	23.787	21.853	−11.943	1.00	72.24	C
ATOM	11015	C	THR	C	394	25.329	19.195	−11.248	1.00	71.33	C
ATOM	11016	O	THR	C	394	26.324	19.027	−11.978	1.00	71.13	O
ATOM	11018	N	ALA	C	395	24.321	18.325	−11.145	1.00	70.98	N
ATOM	11019	CA	ALA	C	395	24.228	17.136	−12.002	1.00	70.55	C
ATOM	11021	CB	ALA	C	395	23.264	16.075	−11.389	1.00	70.05	C
ATOM	11025	C	ALA	C	395	23.782	17.571	−13.408	1.00	69.91	C
ATOM	11026	O	ALA	C	395	23.225	18.653	−13.586	1.00	70.86	O
ATOM	11028	N	HIS	C	396	24.078	16.746	−14.401	1.00	69.20	N
ATOM	11029	CA	HIS	C	396	23.505	16.847	−15.752	1.00	68.85	C
ATOM	11031	CB	HIS	C	396	24.065	15.686	−16.596	1.00	68.90	C
ATOM	11034	CG	HIS	C	396	23.862	15.805	−18.069	1.00	67.91	C
ATOM	11035	ND1	HIS	C	396	24.410	16.820	−18.808	1.00	69.95	N
ATOM	11037	CE1	HIS	C	396	24.127	16.636	−20.084	1.00	69.30	C
ATOM	11039	NE2	HIS	C	396	23.412	15.536	−20.200	1.00	68.35	N
ATOM	11041	CD2	HIS	C	396	23.276	14.972	−18.959	1.00	68.13	C
ATOM	11043	C	HIS	C	396	21.958	16.770	−15.686	1.00	68.93	C
ATOM	11044	O	HIS	C	396	21.388	16.187	−14.745	1.00	68.51	O
ATOM	11046	N	ALA	C	397	21.297	17.409	−16.663	1.00	69.13	N
ATOM	11047	CA	ALA	C	397	19.879	17.141	−16.992	1.00	68.99	C
ATOM	11049	CB	ALA	C	397	19.431	18.012	−18.156	1.00	68.62	C
ATOM	11053	C	ALA	C	397	19.805	15.681	−17.393	1.00	69.26	C
ATOM	11054	O	ALA	C	397	20.767	15.146	−17.877	1.00	69.54	O
ATOM	11056	N	GLY	C	398	18.706	14.990	−17.167	1.00	69.84	N
ATOM	11057	CA	GLY	C	398	18.670	13.539	−17.489	1.00	70.32	C
ATOM	11060	C	GLY	C	398	19.658	12.642	−16.733	1.00	70.29	C
ATOM	11061	O	GLY	C	398	20.011	11.569	−17.204	1.00	70.14	O
ATOM	11063	N	ALA	C	399	20.153	13.129	−15.598	1.00	70.65	N
ATOM	11064	CA	ALA	C	399	20.597	12.289	−14.501	1.00	70.68	C
ATOM	11066	CB	ALA	C	399	21.698	12.961	−13.703	1.00	70.53	C
ATOM	11070	C	ALA	C	399	19.316	12.190	−13.704	1.00	70.69	C
ATOM	11071	O	ALA	C	399	18.622	13.204	−13.536	1.00	70.86	O
ATOM	11073	N	LYS	C	400	18.987	10.974	−13.280	1.00	70.64	N
ATOM	11074	CA	LYS	C	400	17.739	10.662	−12.605	1.00	70.72	C
ATOM	11076	CB	LYS	C	400	16.939	9.709	−13.484	1.00	70.39	C
ATOM	11079	CG	LYS	C	400	16.344	10.387	−14.742	1.00	69.61	C
ATOM	11085	C	LYS	C	400	18.062	10.077	−11.219	1.00	71.47	C
ATOM	11086	O	LYS	C	400	19.159	9.522	−11.011	1.00	72.39	O
ATOM	11088	N	PHE	C	401	17.136	10.221	−10.264	1.00	71.61	N
ATOM	11089	CA	PHE	C	401	17.444	10.011	−8.833	1.00	71.70	C
ATOM	11091	CB	PHE	C	401	17.774	11.362	−8.183	1.00	72.45	C
ATOM	11094	CG	PHE	C	401	19.085	11.921	−8.646	1.00	73.32	C
ATOM	11095	CD1	PHE	C	401	20.301	11.378	−8.149	1.00	72.55	C
ATOM	11097	CE1	PHE	C	401	21.549	11.858	−8.584	1.00	72.75	C
ATOM	11099	CZ	PHE	C	401	21.592	12.874	−9.566	1.00	73.50	C
ATOM	11101	CE2	PHE	C	401	20.367	13.422	−10.090	1.00	74.20	C
ATOM	11103	CD2	PHE	C	401	19.123	12.929	−9.633	1.00	73.60	C
ATOM	11105	C	PHE	C	401	16.325	9.360	−8.051	1.00	71.66	C
ATOM	11106	O	PHE	C	401	15.184	9.375	−8.540	1.00	71.81	O
ATOM	11108	N	PRO	C	402	16.634	8.790	−6.859	1.00	71.00	N
ATOM	11109	CA	PRO	C	402	15.576	8.365	−5.893	1.00	70.25	C
ATOM	11111	CB	PRO	C	402	16.356	7.729	−4.727	1.00	70.20	C
ATOM	11114	CG	PRO	C	402	17.805	8.042	−4.962	1.00	70.93	C
ATOM	11117	CD	PRO	C	402	17.990	8.440	−6.382	1.00	70.75	C
ATOM	11120	C	PRO	C	402	14.765	9.564	−5.421	1.00	69.78	C
ATOM	11121	O	PRO	C	402	15.288	10.402	−4.716	1.00	69.93	O
ATOM	11122	N	ILE	C	403	13.516	9.646	−5.864	1.00	69.19	N
ATOM	11123	CA	ILE	C	403	12.581	10.755	−5.554	1.00	68.73	C
ATOM	11125	CB	ILE	C	403	11.183	10.428	−6.224	1.00	68.84	C
ATOM	11127	CG1	ILE	C	403	11.235	10.562	−7.753	1.00	68.58	C
ATOM	11130	CD1	ILE	C	403	11.256	11.996	−8.261	1.00	69.05	C
ATOM	11134	CG2	ILE	C	403	10.016	11.267	−5.635	1.00	69.41	C
ATOM	11138	C	ILE	C	403	12.379	10.958	−4.047	1.00	67.74	C
ATOM	11139	O	ILE	C	403	12.536	12.075	−3.516	1.00	67.49	O
ATOM	11141	N	LYS	C	404	11.986	9.859	−3.398	1.00	67.02	N
ATOM	11142	CA	LYS	C	404	11.675	9.800	−1.957	1.00	66.38	C
ATOM	11144	CB	LYS	C	404	11.238	8.362	−1.537	1.00	67.26	C
ATOM	11147	CG	LYS	C	404	9.679	8.043	−1.625	1.00	67.27	C
ATOM	11150	CD	LYS	C	404	9.274	7.204	−2.843	1.00	67.48	C
ATOM	11153	CE	LYS	C	404	7.829	6.564	−2.722	1.00	68.82	C
ATOM	11156	NZ	LYS	C	404	6.592	7.470	−2.719	1.00	67.65	N
ATOM	11160	C	LYS	C	404	12.789	10.296	−1.025	1.00	65.74	C
ATOM	11161	O	LYS	C	404	12.488	10.806	0.040	1.00	65.72	O
ATOM	11163	N	TRP	C	405	14.047	10.166	−1.445	1.00	65.01	N
ATOM	11164	CA	TRP	C	405	15.240	10.572	−0.670	1.00	64.62	C
ATOM	11166	CB	TRP	C	405	16.323	9.513	−0.823	1.00	64.67	C
ATOM	11169	CG	TRP	C	405	16.049	8.320	−0.095	1.00	64.45	C
ATOM	11170	CD1	TRP	C	405	16.520	8.012	1.120	1.00	65.58	C
ATOM	11172	NE1	TRP	C	405	16.051	6.786	1.510	1.00	65.01	N
ATOM	11174	CE2	TRP	C	405	15.250	6.290	0.527	1.00	63.89	C
ATOM	11175	CD2	TRP	C	405	15.226	7.242	−0.500	1.00	64.50	C
ATOM	11176	CE3	TRP	C	405	14.450	6.974	−1.639	1.00	67.12	C
ATOM	11178	CZ3	TRP	C	405	13.739	5.750	−1.714	1.00	65.92	C
ATOM	11180	CH2	TRP	C	405	13.802	4.824	−0.670	1.00	65.18	C
ATOM	11182	CZ2	TRP	C	405	14.545	5.077	0.458	1.00	65.58	C
ATOM	11184	C	TRP	C	405	15.861	11.904	−1.082	1.00	63.51	C
ATOM	11185	O	TRP	C	405	16.639	12.463	−0.340	1.00	63.56	O
ATOM	11187	N	THR	C	406	15.537	12.394	−2.266	1.00	62.80	N
ATOM	11188	CA	THR	C	406	16.234	13.526	−2.872	1.00	62.12	C
ATOM	11190	CB	THR	C	406	16.311	13.308	−4.359	1.00	61.77	C
ATOM	11192	OG1	THR	C	406	16.999	12.068	−4.619	1.00	62.35	O
ATOM	11194	CG2	THR	C	406	17.162	14.374	−5.014	1.00	62.34	C
ATOM	11198	C	THR	C	406	15.523	14.838	−2.590	1.00	61.42	C
ATOM	11199	O	THR	C	406	14.342	14.942	−2.881	1.00	61.79	O
ATOM	11201	N	ALA	C	407	16.284	15.823	−2.101	1.00	60.77	N
ATOM	11202	CA	ALA	C	407	15.812	17.123	−1.636	1.00	60.47	C
ATOM	11204	CB	ALA	C	407	16.955	17.906	−1.038	1.00	60.58	C
ATOM	11208	C	ALA	C	407	15.239	17.915	−2.770	1.00	60.58	C
ATOM	11209	O	ALA	C	407	15.708	17.750	−3.867	1.00	60.96	O
ATOM	11211	N	PRO	C	408	14.280	18.803	−2.522	1.00	61.15	N
ATOM	11212	CA	PRO	C	408	13.472	19.377	−3.608	1.00	61.80	C
ATOM	11214	CB	PRO	C	408	12.451	20.271	−2.881	1.00	61.86	C
ATOM	11217	CG	PRO	C	408	12.507	19.862	−1.453	1.00	62.01	C
ATOM	11220	CD	PRO	C	408	13.913	19.389	−1.220	1.00	61.47	C
ATOM	11223	C	PRO	C	408	14.297	20.189	−4.601	1.00	62.35	C
ATOM	11224	O	PRO	C	408	14.228	19.910	−5.812	1.00	62.82	O
ATOM	11225	N	GLU	C	409	15.114	21.127	−4.109	1.00	62.31	N
ATOM	11226	CA	GLU	C	409	16.021	21.857	−5.012	1.00	62.90	C
ATOM	11228	CB	GLU	C	409	16.902	22.887	−4.293	1.00	63.27	C
ATOM	11231	CG	GLU	C	409	18.113	22.355	−3.525	1.00	64.22	C
ATOM	11234	CD	GLU	C	409	17.762	21.616	−2.264	1.00	65.78	C
ATOM	11235	OE1	GLU	C	409	16.585	21.657	−1.816	1.00	67.23	O
ATOM	11236	OE2	GLU	C	409	18.701	21.013	−1.718	1.00	66.21	O
ATOM	11237	C	GLU	C	409	16.888	20.948	−5.896	1.00	62.99	C
ATOM	11238	O	GLU	C	409	17.278	21.347	−6.989	1.00	62.76	O
ATOM	11240	N	SER	C	410	17.192	19.743	−5.415	1.00	63.15	N
ATOM	11241	CA	SER	C	410	17.865	18.753	−6.240	1.00	63.25	C
ATOM	11243	CB	SER	C	410	18.477	17.663	−5.410	1.00	63.19	C
ATOM	11246	OG	SER	C	410	19.269	18.227	−4.376	1.00	63.97	O
ATOM	11248	C	SER	C	410	16.941	18.209	−7.300	1.00	63.52	C
ATOM	11249	O	SER	C	410	17.303	18.201	−8.465	1.00	63.50	O
ATOM	11251	N	LEU	C	411	15.731	17.821	−6.926	1.00	63.76	N
ATOM	11252	CA	LEU	C	411	14.762	17.304	−7.917	1.00	64.03	C
ATOM	11254	CB	LEU	C	411	13.449	16.909	−7.253	1.00	64.14	C
ATOM	11257	CG	LEU	C	411	13.414	15.864	−6.162	1.00	64.13	C
ATOM	11259	CD1	LEU	C	411	11.990	15.856	−5.602	1.00	64.88	C
ATOM	11263	CD2	LEU	C	411	13.827	14.511	−6.689	1.00	63.93	C
ATOM	11267	C	LEU	C	411	14.416	18.309	−9.027	1.00	64.15	C
ATOM	11268	O	LEU	C	411	14.305	17.931	−10.190	1.00	63.79	O
ATOM	11270	N	ALA	C	412	14.217	19.571	−8.647	1.00	64.50	N
ATOM	11271	CA	ALA	C	412	13.785	20.597	−9.591	1.00	64.93	C
ATOM	11273	CB	ALA	C	412	12.992	21.694	−8.887	1.00	65.10	C
ATOM	11277	C	ALA	C	412	15.013	21.156	−10.279	1.00	65.29	C
ATOM	11278	O	ALA	C	412	15.191	20.925	−11.470	1.00	65.59	O
ATOM	11280	N	TYR	C	413	15.889	21.802	−9.493	1.00	65.68	N
ATOM	11281	CA	TYR	C	413	17.092	22.540	−9.975	1.00	65.29	C
ATOM	11283	CB	TYR	C	413	17.447	23.672	−8.945	1.00	66.55	C
ATOM	11286	CG	TYR	C	413	18.031	24.943	−9.522	1.00	67.76	C
ATOM	11287	CD1	TYR	C	413	19.430	25.064	−9.731	1.00	69.64	C
ATOM	11289	CE1	TYR	C	413	20.002	26.240	−10.304	1.00	69.05	C
ATOM	11291	CZ	TYR	C	413	19.167	27.314	−10.662	1.00	68.46	C
ATOM	11292	OH	TYR	C	413	19.744	28.441	−11.203	1.00	67.66	O
ATOM	11294	CE2	TYR	C	413	17.769	27.226	−10.462	1.00	68.13	C
ATOM	11296	CD2	TYR	C	413	17.207	26.039	−9.873	1.00	68.59	C
ATOM	11298	C	TYR	C	413	18.332	21.635	−10.303	1.00	64.82	C
ATOM	11299	O	TYR	C	413	19.337	22.147	−10.793	1.00	63.99	O
ATOM	11301	N	ASN	C	414	18.247	20.309	−10.043	1.00	64.70	N
ATOM	11302	CA	ASN	C	414	19.322	19.296	−10.289	1.00	64.39	C
ATOM	11304	CB	ASN	C	414	19.393	18.954	−11.797	1.00	64.22	C
ATOM	11307	CG	ASN	C	414	19.396	17.421	−12.092	1.00	65.28	C
ATOM	11308	OD1	ASN	C	414	19.724	16.597	−11.254	1.00	69.93	O
ATOM	11309	ND2	ASN	C	414	19.037	17.061	−13.300	1.00	66.74	N
ATOM	11312	C	ASN	C	414	20.702	19.644	−9.632	1.00	64.39	C
ATOM	11313	O	ASN	C	414	21.788	19.360	−10.171	1.00	64.68	O
ATOM	11315	N	LYS	C	415	20.611	20.251	−8.445	1.00	63.86	N
ATOM	11316	CA	LYS	C	415	21.721	20.904	−7.742	1.00	63.81	C
ATOM	11318	CB	LYS	C	415	21.437	22.421	−7.596	1.00	63.79	C
ATOM	11321	CG	LYS	C	415	22.135	23.135	−6.425	1.00	63.57	C
ATOM	11324	CD	LYS	C	415	22.243	24.640	−6.601	1.00	64.50	C
ATOM	11327	CE	LYS	C	415	20.908	25.402	−6.506	1.00	65.40	C
ATOM	11330	NZ	LYS	C	415	21.060	26.771	−7.204	1.00	63.55	N
ATOM	11334	C	LYS	C	415	21.845	20.248	−6.388	1.00	63.23	C
ATOM	11335	O	LYS	C	415	20.854	20.063	−5.710	1.00	63.74	O
ATOM	11337	N	PHE	C	416	23.060	19.934	−5.980	1.00	62.99	N
ATOM	11338	CA	PHE	C	416	23.292	19.177	−4.764	1.00	62.98	C
ATOM	11340	CB	PHE	C	416	23.854	17.811	−5.116	1.00	63.16	C
ATOM	11343	CG	PHE	C	416	22.850	16.910	−5.759	1.00	61.73	C
ATOM	11344	CD1	PHE	C	416	22.690	16.893	−7.125	1.00	62.22	C
ATOM	11346	CE1	PHE	C	416	21.758	16.076	−7.730	1.00	61.97	C
ATOM	11348	CZ	PHE	C	416	20.981	15.232	−6.962	1.00	63.09	C
ATOM	11350	CE2	PHE	C	416	21.135	15.225	−5.590	1.00	64.18	C
ATOM	11352	CD2	PHE	C	416	22.065	16.084	−4.995	1.00	63.42	C
ATOM	11354	C	PHE	C	416	24.230	19.944	−3.872	1.00	63.57	C
ATOM	11355	O	PHE	C	416	25.089	20.686	−4.353	1.00	63.90	O
ATOM	11357	N	SER	C	417	24.012	19.811	−2.568	1.00	64.17	N
ATOM	11358	CA	SER	C	417	24.756	20.573	−1.528	1.00	64.65	C
ATOM	11360	CB	SER	C	417	24.024	21.868	−1.089	1.00	64.47	C
ATOM	11363	OG	SER	C	417	22.686	21.628	−0.683	1.00	63.36	O
ATOM	11365	C	SER	C	417	24.949	19.641	−0.373	1.00	64.77	C
ATOM	11366	O	SER	C	417	24.451	18.516	−0.393	1.00	66.61	O
ATOM	11368	N	ILE	C	418	25.695	20.056	0.620	1.00	64.58	N
ATOM	11369	CA	ILE	C	418	25.841	19.221	1.803	1.00	65.24	C
ATOM	11371	CB	ILE	C	418	27.126	19.634	2.597	1.00	65.52	C
ATOM	11373	CG	ILE	C	418	27.825	18.414	3.190	1.00	65.99	C
ATOM	11376	CD1	ILE	C	418	26.993	17.587	4.069	1.00	66.69	C
ATOM	11380	CG2	ILE	C	418	26.866	20.795	3.589	1.00	66.57	C
ATOM	11384	C	ILE	C	418	24.496	19.256	2.574	1.00	65.30	C
ATOM	11385	O	ILE	C	418	24.092	18.278	3.197	1.00	65.56	O
ATOM	11387	N	LYS	C	419	23.794	20.387	2.455	1.00	65.61	N
ATOM	11388	CA	LYS	C	419	22.362	20.529	2.822	1.00	65.17	C
ATOM	11390	CB	LYS	C	419	21.902	22.011	2.643	1.00	64.70	C
ATOM	11393	CG	LYS	C	419	22.002	22.901	3.904	1.00	64.72	C
ATOM	11396	CD	LYS	C	419	23.183	22.584	4.862	1.00	65.40	C
ATOM	11399	CE	LYS	C	419	23.324	23.640	5.973	1.00	65.56	C
ATOM	11402	NZ	LYS	C	419	24.144	23.236	7.162	1.00	65.98	N
ATOM	11406	C	LYS	C	419	21.390	19.537	2.147	1.00	64.78	C
ATOM	11407	O	LYS	C	419	20.423	19.128	2.771	1.00	64.66	O
ATOM	11409	N	SER	C	420	21.643	19.155	0.902	1.00	64.79	N
ATOM	11410	CA	SER	C	420	20.840	18.127	0.244	1.00	65.00	C
ATOM	11412	CB	SER	C	420	21.082	18.090	−1.256	1.00	65.01	C
ATOM	11415	OG	SER	C	420	22.237	17.329	−1.552	1.00	65.99	O
ATOM	11417	C	SER	C	420	21.108	16.741	0.832	1.00	65.13	C
ATOM	11418	O	SER	C	420	20.180	15.937	0.877	1.00	65.68	O
ATOM	11420	N	ASP	C	421	22.359	16.452	1.232	1.00	64.87	N
ATOM	11421	CA	ASP	C	421	22.668	15.238	2.063	1.00	64.62	C
ATOM	11423	CB	ASP	C	421	24.188	15.056	2.284	1.00	64.75	C
ATOM	11426	CG	ASP	C	421	24.875	14.179	1.210	1.00	66.91	C
ATOM	11427	OD1	ASP	C	421	24.308	13.811	0.143	1.00	65.03	O
ATOM	11428	OD2	ASP	C	421	26.070	13.823	1.363	1.00	71.00	O
ATOM	11429	C	ASP	C	421	21.967	15.247	3.435	1.00	64.01	C
ATOM	11430	O	ASP	C	421	21.677	14.179	3.999	1.00	62.96	O
ATOM	11432	N	VAL	C	422	21.731	16.451	3.972	1.00	63.60	N
ATOM	11433	CA	VAL	C	422	21.019	16.628	5.252	1.00	63.45	C
ATOM	11435	CB	VAL	C	422	21.172	18.101	5.807	1.00	63.50	C
ATOM	11437	CG1	VAL	C	422	20.125	18.478	6.875	1.00	63.36	C
ATOM	11441	CG2	VAL	C	422	22.569	18.282	6.354	1.00	63.53	C
ATOM	11445	C	VAL	C	422	19.570	16.166	5.108	1.00	62.50	C
ATOM	11446	O	VAL	C	422	19.112	15.324	5.869	1.00	62.85	O
ATOM	11448	N	TRP	C	423	18.877	16.670	4.106	1.00	61.37	N
ATOM	11449	CA	TRP	C	423	17.556	16.158	3.768	1.00	60.68	C
ATOM	11451	CB	TRP	C	423	17.077	16.748	2.448	1.00	60.79	C
ATOM	11454	CG	TRP	C	423	15.678	16.387	2.096	1.00	60.20	C
ATOM	11455	CD1	TRP	C	423	15.198	15.157	1.722	1.00	60.05	C
ATOM	11457	NE1	TRP	C	423	13.849	15.226	1.496	1.00	60.53	N
ATOM	11459	CE2	TRP	C	423	13.445	16.518	1.699	1.00	60.68	C
ATOM	11460	CD2	TRP	C	423	14.585	17.265	2.075	1.00	59.41	C
ATOM	11461	CE3	TRP	C	423	14.435	18.619	2.353	1.00	60.05	C
ATOM	11463	CZ3	TRP	C	423	13.167	19.192	2.247	1.00	60.92	C
ATOM	11465	CH2	TRP	C	423	12.046	18.422	1.866	1.00	60.42	C
ATOM	11467	CZ2	TRP	C	423	12.164	17.092	1.584	1.00	60.72	C
ATOM	11469	C	TRP	C	423	17.564	14.630	3.665	1.00	60.18	C
ATOM	11470	O	TRP	C	423	16.725	13.966	4.300	1.00	60.57	O
ATOM	11472	N	ALA	C	424	18.488	14.088	2.872	1.00	59.04	N
ATOM	11473	CA	ALA	C	424	18.608	12.633	2.728	1.00	59.02	C
ATOM	11475	CB	ALA	C	424	19.723	12.287	1.796	1.00	58.35	C
ATOM	11479	C	ALA	C	424	18.804	11.917	4.089	1.00	59.41	C
ATOM	11480	O	ALA	C	424	18.193	10.865	4.343	1.00	59.00	O
ATOM	11482	N	PHE	C	425	19.641	12.510	4.960	1.00	59.99	N
ATOM	11483	CA	PHE	C	425	19.869	11.987	6.331	1.00	60.03	C
ATOM	11485	CB	PHE	C	425	20.888	12.820	7.128	1.00	59.91	C
ATOM	11488	CG	PHE	C	425	21.224	12.231	8.475	1.00	59.16	C
ATOM	11489	CD1	PHE	C	425	22.074	11.138	8.577	1.00	57.62	C
ATOM	11491	CE1	PHE	C	425	22.385	10.583	9.830	1.00	57.67	C
ATOM	11493	CZ	PHE	C	425	21.812	11.107	10.977	1.00	58.54	C
ATOM	11495	CE2	PHE	C	425	20.953	12.192	10.892	1.00	58.25	C
ATOM	11497	CD2	PHE	C	425	20.683	12.768	9.642	1.00	59.67	C
ATOM	11499	C	PHE	C	425	18.569	11.931	7.110	1.00	60.64	C
ATOM	11500	O	PHE	C	425	18.291	10.899	7.761	1.00	61.54	O
ATOM	11502	N	GLY	C	426	17.782	13.017	7.019	1.00	60.36	N
ATOM	11503	CA	GLY	C	426	16.415	13.066	7.557	1.00	60.23	C
ATOM	11506	C	GLY	C	426	15.568	11.865	7.162	1.00	60.14	C
ATOM	11507	O	GLY	C	426	14.963	11.247	8.014	1.00	59.96	O
ATOM	11509	N	VAL	C	427	15.569	11.520	5.872	1.00	60.35	N
ATOM	11510	CA	VAL	C	427	14.756	10.425	5.349	1.00	60.65	C
ATOM	11512	CB	VAL	C	427	14.727	10.377	3.798	1.00	60.79	C
ATOM	11514	CG1	VAL	C	427	14.020	9.087	3.261	1.00	60.27	C
ATOM	11518	CG2	VAL	C	427	14.028	11.611	3.252	1.00	59.88	C
ATOM	11522	C	VAL	C	427	15.304	9.143	5.865	1.00	61.60	C
ATOM	11523	O	VAL	C	427	14.541	8.252	6.252	1.00	61.44	O
ATOM	11525	N	LEU	C	428	16.633	9.048	5.869	1.00	63.04	N
ATOM	11526	CA	LEU	C	428	17.318	7.884	6.450	1.00	63.78	C
ATOM	11528	CB	LEU	C	428	18.837	8.032	6.316	1.00	63.91	C
ATOM	11531	CG	LEU	C	428	19.753	7.050	7.039	1.00	63.83	C
ATOM	11533	CD1	LEU	C	428	19.481	5.669	6.545	1.00	65.35	C
ATOM	11537	CD2	LEU	C	428	21.219	7.426	6.782	1.00	64.37	C
ATOM	11541	C	LEU	C	428	16.912	7.659	7.905	1.00	64.10	C
ATOM	11542	O	LEU	C	428	16.733	6.515	8.301	1.00	64.36	O
ATOM	11544	N	LEU	C	429	16.741	8.732	8.692	1.00	64.22	N
ATOM	11545	CA	LEU	C	429	16.229	8.553	10.056	1.00	64.70	C
ATOM	11547	CB	LEU	C	429	16.039	9.852	10.831	1.00	64.27	C
ATOM	11550	CG	LEU	C	429	17.265	10.653	11.206	1.00	64.56	C
ATOM	11552	CD1	LEU	C	429	16.773	11.829	12.074	1.00	66.15	C
ATOM	11556	CD2	LEU	C	429	18.326	9.836	11.951	1.00	62.69	C
ATOM	11560	C	LEU	C	429	14.900	7.836	10.030	1.00	65.09	C
ATOM	11561	O	LEU	C	429	14.733	6.855	10.750	1.00	65.48	O
ATOM	11563	N	TRP	C	430	13.996	8.329	9.176	1.00	65.33	N
ATOM	11564	CA	TRP	C	430	12.631	7.820	9.059	1.00	65.18	C
ATOM	11566	CB	TRP	C	430	11.816	8.641	8.039	1.00	65.11	C
ATOM	11569	CG	TRP	C	430	10.343	8.417	8.125	1.00	65.31	C
ATOM	11570	CD1	TRP	C	430	9.414	9.164	8.812	1.00	64.90	C
ATOM	11572	NE1	TRP	C	430	8.157	8.628	8.652	1.00	64.23	N
ATOM	11574	CE2	TRP	C	430	8.253	7.516	7.856	1.00	64.09	C
ATOM	11575	CD2	TRP	C	430	9.618	7.359	7.501	1.00	65.33	C
ATOM	11576	CE3	TRP	C	430	9.985	6.281	6.667	1.00	64.19	C
ATOM	11578	CZ3	TRP	C	430	9.006	5.425	6.216	1.00	64.96	C
ATOM	11580	CH2	TRP	C	430	7.652	5.616	6.584	1.00	65.28	C
ATOM	11582	CZ2	TRP	C	430	7.264	6.658	7.399	1.00	64.42	C
ATOM	11584	C	TRP	C	430	12.670	6.338	8.734	1.00	65.08	C
ATOM	11585	O	TRP	C	430	12.027	5.565	9.424	1.00	65.21	O
ATOM	11587	N	GLU	C	431	13.493	5.931	7.771	1.00	65.64	N
ATOM	11588	CA	GLU	C	431	13.718	4.484	7.514	1.00	66.77	C
ATOM	11590	CB	GLU	C	431	14.783	4.217	6.449	1.00	66.67	C
ATOM	11593	CG	GLU	C	431	14.378	4.435	4.994	1.00	67.87	C
ATOM	11596	CD	GLU	C	431	15.589	4.299	4.062	1.00	69.49	C
ATOM	11597	OE1	GLU	C	431	16.544	5.131	4.187	1.00	72.37	O
ATOM	11598	OE2	GLU	C	431	15.630	3.342	3.230	1.00	74.52	O
ATOM	11599	C	GLU	C	431	14.135	3.764	8.790	1.00	66.48	C
ATOM	11600	O	GLU	C	431	13.500	2.773	9.144	1.00	66.86	O
ATOM	11602	N	ILE	C	432	15.153	4.285	9.493	1.00	66.47	N
ATOM	11603	CA	ILE	C	432	15.586	3.679	10.766	1.00	66.46	C
ATOM	11605	CB	ILE	C	432	16.751	4.416	11.469	1.00	66.66	C
ATOM	11607	CG1	ILE	C	432	18.040	4.318	10.652	1.00	67.24	C
ATOM	11610	CD1	ILE	C	432	19.270	5.023	11.265	1.00	66.69	C
ATOM	11614	CG2	ILE	C	432	17.019	3.767	12.860	1.00	66.74	C
ATOM	11618	C	ILE	C	432	14.438	3.580	11.741	1.00	66.30	C
ATOM	11619	O	ILE	C	432	14.201	2.504	12.247	1.00	66.62	O
ATOM	11621	N	ALA	C	433	13.776	4.714	12.008	1.00	66.57	N
ATOM	11622	CA	ALA	C	433	12.605	4.827	12.911	1.00	66.43	C
ATOM	11624	CB	ALA	C	433	11.978	6.198	12.808	1.00	66.42	C
ATOM	11628	C	ALA	C	433	11.551	3.768	12.660	1.00	66.85	C
ATOM	11629	O	ALA	C	433	11.168	3.039	13.578	1.00	67.30	O
ATOM	11631	N	THR	C	434	11.167	3.609	11.397	1.00	67.29	N
ATOM	11632	CA	THR	C	434	10.130	2.621	11.000	1.00	67.68	C
ATOM	11634	CB	THR	C	434	9.569	3.023	9.653	1.00	67.35	C
ATOM	11636	OG1	THR	C	434	10.649	3.146	8.720	1.00	65.05	O
ATOM	11638	CG2	THR	C	434	8.922	4.411	9.720	1.00	67.46	C
ATOM	11642	C	THR	C	434	10.579	1.156	10.872	1.00	68.37	C
ATOM	11643	O	THR	C	434	9.754	0.314	10.524	1.00	68.47	O
ATOM	11645	N	TYR	C	435	11.859	0.860	11.140	1.00	69.30	N
ATOM	11646	CA	TYR	C	435	12.511	−0.399	10.767	1.00	69.71	C
ATOM	11648	CB	TYR	C	435	12.085	−1.533	11.703	1.00	70.66	C
ATOM	11651	CG	TYR	C	435	12.405	−1.389	13.176	1.00	71.44	C
ATOM	11652	CD1	TYR	C	435	11.530	−0.717	14.046	1.00	71.73	C
ATOM	11654	CE1	TYR	C	435	11.801	−0.635	15.422	1.00	71.50	C
ATOM	11656	CZ	TYR	C	435	12.955	−1.240	15.942	1.00	71.43	C
ATOM	11657	OH	TYR	C	435	13.233	−1.159	17.285	1.00	70.91	O
ATOM	11659	CE2	TYR	C	435	13.837	−1.908	15.102	1.00	71.38	C
ATOM	11661	CD2	TYR	C	435	13.551	−1.994	13.725	1.00	71.86	C
ATOM	11663	C	TYR	C	435	12.242	−0.812	9.310	1.00	70.16	C
ATOM	11664	O	TYR	C	435	11.748	−1.917	9.038	1.00	70.08	O
ATOM	11666	N	GLY	C	436	12.522	0.107	8.389	1.00	70.74	N
ATOM	11667	CA	GLY	C	436	12.554	−0.182	6.942	1.00	71.05	C
ATOM	11670	C	GLY	C	436	11.288	−0.010	6.112	1.00	71.37	C
ATOM	11671	O	GLY	C	436	11.169	−0.636	5.068	1.00	71.52	O
ATOM	11673	N	MET	C	437	10.354	0.846	6.532	1.00	71.88	N
ATOM	11674	CA	MET	C	437	9.205	1.230	5.669	1.00	72.07	C
ATOM	11676	CB	MET	C	437	8.093	1.942	6.466	1.00	72.35	C
ATOM	11679	CG	MET	C	437	7.304	1.032	7.388	1.00	73.14	C
ATOM	11682	SD	MET	C	437	5.718	0.449	6.710	1.00	77.41	S
ATOM	11683	CE	MET	C	437	6.067	−0.178	4.944	1.00	76.82	C
ATOM	11687	C	MET	C	437	9.624	2.111	4.462	1.00	72.11	C
ATOM	11688	O	MET	C	437	10.638	2.812	4.486	1.00	70.63	O
ATOM	11690	N	SER	C	438	8.811	2.028	3.410	1.00	72.63	N
ATOM	11691	CA	SER	C	438	9.010	2.809	2.205	1.00	72.91	C
ATOM	11693	CB	SER	C	438	8.191	2.267	1.024	1.00	73.08	C
ATOM	11696	OG	SER	C	438	9.050	1.809	−0.003	1.00	74.83	O
ATOM	11698	C	SER	C	438	8.593	4.236	2.534	1.00	72.89	C
ATOM	11699	O	SER	C	438	7.476	4.461	3.031	1.00	73.11	O
ATOM	11701	N	PRO	C	439	9.470	5.203	2.296	1.00	72.80	N
ATOM	11702	CA	PRO	C	439	9.097	6.606	2.504	1.00	72.72	C
ATOM	11704	CB	PRO	C	439	10.348	7.387	2.125	1.00	72.54	C
ATOM	11707	CG	PRO	C	439	11.441	6.388	1.993	1.00	72.87	C
ATOM	11710	CD	PRO	C	439	10.877	5.047	1.887	1.00	72.60	C
ATOM	11713	C	PRO	C	439	7.895	7.063	1.685	1.00	72.94	C
ATOM	11714	O	PRO	C	439	7.567	6.447	0.667	1.00	72.60	O
ATOM	11715	N	TYR	C	440	7.244	8.120	2.187	1.00	73.33	N
ATOM	11716	CA	TYR	C	440	5.986	8.680	1.650	1.00	73.29	C
ATOM	11718	CB	TYR	C	440	6.280	9.555	0.460	1.00	72.16	C
ATOM	11721	CG	TYR	C	440	7.163	10.684	0.865	1.00	70.93	C
ATOM	11722	CD1	TYR	C	440	6.627	11.844	1.412	1.00	69.86	C
ATOM	11724	CE1	TYR	C	440	7.445	12.891	1.799	1.00	69.75	C
ATOM	11726	CZ	TYR	C	440	8.807	12.755	1.657	1.00	69.27	C
ATOM	11727	OH	TYR	C	440	9.648	13.757	2.022	1.00	70.36	O
ATOM	11729	CE2	TYR	C	440	9.348	11.613	1.125	1.00	68.81	C
ATOM	11731	CD2	TYR	C	440	8.541	10.588	0.741	1.00	69.21	C
ATOM	11733	C	TYR	C	440	4.973	7.566	1.341	1.00	74.44	C
ATOM	11734	O	TYR	C	440	4.634	7.306	0.177	1.00	74.58	O
ATOM	11736	N	PRO	C	441	4.499	6.922	2.414	1.00	75.25	N
ATOM	11737	CA	PRO	C	441	4.168	5.498	2.356	1.00	75.45	C
ATOM	11739	CB	PRO	C	441	3.908	5.136	3.829	1.00	75.52	C
ATOM	11742	CG	PRO	C	441	3.434	6.432	4.472	1.00	75.73	C
ATOM	11745	CD	PRO	C	441	4.162	7.523	3.726	1.00	75.29	C
ATOM	11748	C	PRO	C	441	2.943	5.272	1.487	1.00	75.26	C
ATOM	11749	O	PRO	C	441	1.896	5.849	1.785	1.00	75.41	O
ATOM	11750	N	GLY	C	442	3.107	4.516	0.390	1.00	74.66	N
ATOM	11751	CA	GLY	C	442	2.006	4.244	−0.553	1.00	73.91	C
ATOM	11754	C	GLY	C	442	1.546	5.350	−1.512	1.00	73.50	C
ATOM	11755	O	GLY	C	442	0.620	5.106	−2.264	1.00	73.42	O
ATOM	11757	N	ILE	C	443	2.173	6.536	−1.484	1.00	72.83	N
ATOM	11758	CA	ILE	C	443	1.964	7.623	−2.465	1.00	72.68	C
ATOM	11760	CB	ILE	C	443	2.508	8.994	−1.877	1.00	72.68	C
ATOM	11762	CG1	ILE	C	443	1.696	9.415	−0.643	1.00	73.33	C
ATOM	11765	CD1	ILE	C	443	2.469	10.303	0.333	1.00	73.03	C
ATOM	11769	CG2	ILE	C	443	2.533	10.148	−2.908	1.00	71.95	C
ATOM	11773	C	ILE	C	443	2.702	7.278	−3.778	1.00	72.68	C
ATOM	11774	O	ILE	C	443	3.798	6.689	−3.736	1.00	73.04	O
ATOM	11776	N	ASP	C	444	2.103	7.653	−4.924	1.00	72.20	N
ATOM	11777	CA	ASP	C	444	2.781	7.666	−6.249	1.00	71.48	C
ATOM	11779	CB	ASP	C	444	1.748	7.630	−7.388	1.00	71.56	C
ATOM	11782	CG	ASP	C	444	2.346	7.189	−8.740	1.00	71.74	C
ATOM	11783	OD1	ASP	C	444	3.204	7.909	−9.324	1.00	70.76	O
ATOM	11784	OD2	ASP	C	444	1.971	6.134	−9.304	1.00	70.66	O
ATOM	11785	C	ASP	C	444	3.702	8.901	−6.427	1.00	71.12	C
ATOM	11786	O	ASP	C	444	3.314	10.059	−6.125	1.00	71.08	O
ATOM	11788	N	LEU	C	445	4.869	8.639	−7.030	1.00	70.44	N
ATOM	11789	CA	LEU	C	445	6.037	9.556	−7.048	1.00	69.70	C
ATOM	11791	CB	LEU	C	445	7.239	8.884	−7.743	1.00	69.72	C
ATOM	11794	CG	LEU	C	445	7.709	7.414	−7.577	1.00	69.95	C
ATOM	11796	CD1	LEU	C	445	8.511	6.945	−8.799	1.00	70.38	C
ATOM	11800	CD2	LEU	C	445	8.549	7.202	−6.353	1.00	70.42	C
ATOM	11804	C	LEU	C	445	5.808	10.916	−7.736	1.00	69.14	C
ATOM	11805	O	LEU	C	445	6.550	11.872	−7.499	1.00	68.61	O
ATOM	11807	N	SER	C	446	4.818	10.973	−8.628	1.00	68.94	N
ATOM	11808	CA	SER	C	446	4.480	12.185	−9.408	1.00	68.68	C
ATOM	11810	CB	SER	C	446	3.322	11.878	−10.377	1.00	68.33	C
ATOM	11813	OG	SER	C	446	2.610	10.707	−9.993	1.00	66.71	O
ATOM	11815	C	SER	C	446	4.179	13.435	−8.562	1.00	68.68	C
ATOM	11816	O	SER	C	446	4.671	14.521	−8.878	1.00	68.00	O
ATOM	11818	N	GLN	C	447	3.412	13.250	−7.477	1.00	69.14	N
ATOM	11819	CA	GLN	C	447	2.890	14.370	−6.643	1.00	69.10	C
ATOM	11821	CB	GLN	C	447	1.428	14.121	−6.220	1.00	69.68	C
ATOM	11824	CG	GLN	C	447	0.381	14.835	−7.112	1.00	69.97	C
ATOM	11827	CD	GLN	C	447	0.572	13.881	−7.777	1.00	71.82	C
ATOM	11828	OE1	GLN	C	447	1.789	14.051	−7.689	1.00	74.10	O
ATOM	11829	NE2	GLN	C	447	0.023	12.880	−8.468	1.00	72.26	N
ATOM	11832	C	GLN	C	447	3.716	14.718	−5.427	1.00	68.57	C
ATOM	11833	O	GLN	C	447	3.575	15.845	−4.897	1.00	67.56	O
ATOM	11835	N	VAL	C	448	4.567	13.767	−5.013	1.00	68.40	N
ATOM	11836	CA	VAL	C	448	5.646	13.994	−4.024	1.00	68.20	C
ATOM	11838	CB	VAL	C	448	6.845	12.975	−4.162	1.00	67.98	C
ATOM	11840	CG1	VAL	C	448	8.033	13.380	−3.272	1.00	68.25	C
ATOM	11844	CG2	VAL	C	448	6.436	11.526	−3.795	1.00	67.75	C
ATOM	11848	C	VAL	C	448	6.167	15.436	−4.063	1.00	68.40	C
ATOM	11849	O	VAL	C	448	6.131	16.118	−3.043	1.00	68.13	O
ATOM	11851	N	TYR	C	449	6.591	15.907	−5.236	1.00	68.99	N
ATOM	11852	CA	TYR	C	449	7.249	17.211	−5.302	1.00	69.83	C
ATOM	11854	CB	TYR	C	449	7.898	17.492	−6.659	1.00	69.69	C
ATOM	11857	CG	TYR	C	449	8.546	18.863	−6.639	1.00	69.63	C
ATOM	11858	CD1	TYR	C	449	9.765	19.070	−5.995	1.00	69.64	C
ATOM	11860	CE1	TYR	C	449	10.356	20.342	−5.938	1.00	70.72	C
ATOM	11862	CZ	TYR	C	449	9.706	21.433	−6.525	1.00	70.88	C
ATOM	11863	OH	TYR	C	449	10.264	22.683	−6.483	1.00	70.21	O
ATOM	11865	CE2	TYR	C	449	8.486	21.258	−7.164	1.00	71.25	C
ATOM	11867	CD2	TYR	C	449	7.905	19.973	−7.207	1.00	71.50	C
ATOM	11869	C	TYR	C	449	6.370	18.408	−4.855	1.00	70.32	C
ATOM	11870	O	TYR	C	449	6.768	19.125	−3.928	1.00	70.47	O
ATOM	11872	N	GLU	C	450	5.225	18.630	−5.521	1.00	70.76	N
ATOM	11873	CA	GLU	C	450	4.280	19.732	−5.165	1.00	70.83	C
ATOM	11875	CB	GLU	C	450	2.957	19.618	−5.961	1.00	71.40	C
ATOM	11878	CG	GLU	C	450	3.006	20.014	−7.440	1.00	71.50	C
ATOM	11881	CD	GLU	C	450	1.624	20.038	−8.111	1.00	71.27	C
ATOM	11882	OE1	GLU	C	450	0.693	19.345	−7.614	1.00	70.67	O
ATOM	11883	OE2	GLU	C	450	1.468	20.751	−9.146	1.00	71.43	O
ATOM	11884	C	GLU	C	450	3.928	19.764	−3.665	1.00	70.68	C
ATOM	11885	O	GLU	C	450	3.851	20.841	−3.056	1.00	70.17	O
ATOM	11887	N	LEU	C	451	3.721	18.570	−3.100	1.00	70.51	N
ATOM	11888	CA	LEU	C	451	3.449	18.394	−1.655	1.00	70.44	C
ATOM	11890	CB	LEU	C	451	3.351	16.895	−1.272	1.00	70.04	C
ATOM	11893	CG	LEU	C	451	2.254	16.027	−1.918	1.00	69.02	C
ATOM	11895	CD1	LEU	C	451	2.368	14.526	−1.632	1.00	67.63	C
ATOM	11899	CD2	LEU	C	451	0.933	16.539	−1.478	1.00	69.55	C
ATOM	11903	C	LEU	C	451	4.470	19.080	−0.738	1.00	70.53	C
ATOM	11904	O	LEU	C	451	4.075	19.780	0.218	1.00	70.27	O
ATOM	11906	N	LEU	C	452	5.761	18.886	−1.034	1.00	70.54	N
ATOM	11907	CA	LEU	C	452	6.832	19.363	−0.142	1.00	70.96	C
ATOM	11909	CB	LEU	C	452	8.207	18.767	−0.516	1.00	71.07	C
ATOM	11912	CG	LEU	C	452	8.374	17.222	−0.627	1.00	72.07	C
ATOM	11914	CD1	LEU	C	452	9.673	16.841	−1.365	1.00	72.21	C
ATOM	11918	CD2	LEU	C	452	8.326	16.466	0.699	1.00	71.84	C
ATOM	11922	C	LEU	C	452	6.841	20.898	−0.177	1.00	70.95	C
ATOM	11923	O	LEU	C	452	6.716	21.548	0.863	1.00	70.56	O
ATOM	11925	N	GLU	C	453	6.933	21.442	−1.397	1.00	71.21	N
ATOM	11926	CA	GLU	C	453	6.697	22.881	−1.749	1.00	70.99	C
ATOM	11928	CB	GLU	C	453	6.450	22.966	−3.278	1.00	71.38	C
ATOM	11931	CG	GLU	C	453	5.913	24.262	−3.895	1.00	71.65	C
ATOM	11934	CD	GLU	C	453	4.792	23.980	−4.882	1.00	73.32	C
ATOM	11935	OE1	GLU	C	453	5.035	23.209	−5.847	1.00	74.16	O
ATOM	11936	OE2	GLU	C	453	3.671	24.512	−4.680	1.00	73.67	O
ATOM	11937	C	GLU	C	453	5.564	23.566	−0.987	1.00	70.18	C
ATOM	11938	O	GLU	C	453	5.691	24.727	−0.572	1.00	69.70	O
ATOM	11940	N	LYS	C	454	4.472	22.831	−0.815	1.00	69.51	N
ATOM	11941	CA	LYS	C	454	3.303	23.317	−0.100	1.00	69.10	C
ATOM	11943	CB	LYS	C	454	2.058	22.969	−0.952	1.00	69.19	C
ATOM	11946	CG	LYS	C	454	1.065	24.130	−1.167	1.00	69.12	C
ATOM	11949	CD	LYS	C	454	1.209	25.098	−2.339	1.00	68.69	C
ATOM	11952	CE	LYS	C	454	0.105	26.203	−2.160	1.00	69.15	C
ATOM	11955	NZ	LYS	C	454	0.032	27.209	−3.262	1.00	68.95	N
ATOM	11959	C	LYS	C	454	3.246	22.823	1.401	1.00	69.04	C
ATOM	11960	O	LYS	C	454	2.178	22.740	1.997	1.00	69.22	O
ATOM	11962	N	ASP	C	455	4.409	22.519	1.995	1.00	68.69	N
ATOM	11963	CA	ASP	C	455	4.631	22.334	3.451	1.00	68.14	C
ATOM	11965	CB	ASP	C	455	3.957	23.472	4.274	1.00	68.19	C
ATOM	11968	CG	ASP	C	455	4.923	24.172	5.225	1.00	68.33	C
ATOM	11969	OD1	ASP	C	455	5.255	23.636	6.292	1.00	68.67	O
ATOM	11970	OD2	ASP	C	455	5.404	25.285	4.984	1.00	69.69	O
ATOM	11971	C	ASP	C	455	4.366	20.941	4.084	1.00	67.67	C
ATOM	11972	O	ASP	C	455	4.740	20.740	5.245	1.00	67.12	O
ATOM	11974	N	TYR	C	456	3.786	19.986	3.346	1.00	67.16	N
ATOM	11975	CA	TYR	C	456	3.597	18.598	3.867	1.00	67.09	C
ATOM	11977	CB	TYR	C	456	2.656	17.787	2.963	1.00	67.19	C
ATOM	11980	CG	TYR	C	456	2.590	16.288	3.222	1.00	67.17	C
ATOM	11981	CD1	TYR	C	456	1.757	15.737	4.208	1.00	67.80	C
ATOM	11983	CE1	TYR	C	456	1.712	14.316	4.418	1.00	67.65	C
ATOM	11985	CZ	TYR	C	456	2.503	13.469	3.627	1.00	68.06	C
ATOM	11986	OH	TYR	C	456	2.491	12.097	3.781	1.00	68.80	O
ATOM	11988	CE2	TYR	C	456	3.320	13.998	2.662	1.00	67.61	C
ATOM	11990	CD2	TYR	C	456	3.360	15.404	2.462	1.00	68.37	C
ATOM	11992	C	TYR	C	456	4.911	17.820	4.047	1.00	67.06	C
ATOM	11993	O	TYR	C	456	5.767	17.863	3.171	1.00	67.59	O
ATOM	11995	N	ARG	C	457	5.022	17.082	5.158	1.00	66.75	N
ATOM	11996	CA	ARG	C	457	6.137	16.169	5.463	1.00	66.44	C
ATOM	11998	CB	ARG	C	457	6.932	16.726	6.615	1.00	66.18	C
ATOM	12001	CG	ARG	C	457	7.534	18.069	6.355	1.00	65.80	C
ATOM	12004	CD	ARG	C	457	8.660	18.096	5.332	1.00	64.15	C
ATOM	12007	NE	ARG	C	457	9.058	19.492	5.153	1.00	62.26	N
ATOM	12009	CZ	ARG	C	457	8.821	20.270	4.088	1.00	60.48	C
ATOM	12010	NH1	ARG	C	457	8.243	19.823	2.979	1.00	58.51	N
ATOM	12013	NH2	ARG	C	457	9.228	21.538	4.132	1.00	61.69	N
ATOM	12016	C	ARG	C	457	5.605	14.815	5.895	1.00	66.76	C
ATOM	12017	O	ARG	C	457	4.389	14.639	5.979	1.00	67.72	O
ATOM	12019	N	MET	C	458	6.487	13.850	6.163	1.00	66.57	N
ATOM	12020	CA	MET	C	458	6.034	12.584	6.743	1.00	66.37	C
ATOM	12022	CB	MET	C	458	7.068	11.479	6.604	1.00	66.36	C
ATOM	12025	CG	MET	C	458	7.355	11.139	5.176	1.00	65.86	C
ATOM	12028	SD	MET	C	458	8.109	9.513	4.975	1.00	64.58	S
ATOM	12029	CE	MET	C	458	9.858	9.899	5.056	1.00	64.48	C
ATOM	12033	C	MET	C	458	5.701	12.817	8.201	1.00	67.09	C
ATOM	12034	O	MET	C	458	6.309	13.647	8.859	1.00	67.08	O
ATOM	12036	N	GLU	C	459	4.691	12.110	8.681	1.00	68.27	N
ATOM	12037	CA	GLU	C	459	4.270	12.183	10.090	1.00	69.09	C
ATOM	12039	CB	GLU	C	459	2.801	11.718	10.259	1.00	69.05	C
ATOM	12042	CG	GLU	C	459	2.512	10.212	10.330	1.00	70.70	C
ATOM	12045	CD	GLU	C	459	2.699	9.472	9.015	1.00	73.90	C
ATOM	12046	OE1	GLU	C	459	3.878	9.284	8.570	1.00	77.47	O
ATOM	12047	OE2	GLU	C	459	1.668	9.061	8.419	1.00	73.86	O
ATOM	12048	C	GLU	C	459	5.264	11.387	10.957	1.00	69.28	C
ATOM	12049	O	GLU	C	459	5.896	10.429	10.468	1.00	69.90	O
ATOM	12051	N	ARG	C	460	5.406	11.803	12.216	1.00	69.16	N
ATOM	12052	CA	ARG	C	460	6.280	11.135	13.212	1.00	69.20	C
ATOM	12054	CB	ARG	C	460	6.142	11.874	14.557	1.00	68.99	C
ATOM	12057	CG	ARG	C	460	7.000	11.363	15.729	1.00	70.15	C
ATOM	12060	CD	ARG	C	460	6.706	11.935	17.153	1.00	71.58	C
ATOM	12063	NE	ARG	C	460	5.288	12.203	17.298	1.00	75.72	N
ATOM	12065	CZ	ARG	C	460	4.298	11.269	17.264	1.00	79.30	C
ATOM	12066	NH1	ARG	C	460	4.578	9.946	17.144	1.00	81.87	N
ATOM	12069	NH2	ARG	C	460	3.007	11.667	17.378	1.00	76.78	N
ATOM	12072	C	ARG	C	460	5.881	9.676	13.385	1.00	68.21	C
ATOM	12073	O	ARG	C	460	4.777	9.423	13.820	1.00	69.06	O
ATOM	12075	N	PRO	C	461	6.733	8.708	13.072	1.00	67.64	N
ATOM	12076	CA	PRO	C	461	6.346	7.298	13.220	1.00	67.50	C
ATOM	12078	CB	PRO	C	461	7.504	6.533	12.559	1.00	67.37	C
ATOM	12081	CG	PRO	C	461	8.644	7.403	12.621	1.00	67.48	C
ATOM	12084	CD	PRO	C	461	8.123	8.829	12.611	1.00	67.94	C
ATOM	12087	C	PRO	C	461	6.182	6.896	14.697	1.00	67.77	C
ATOM	12088	O	PRO	C	461	6.638	7.639	15.583	1.00	68.41	O
ATOM	12089	N	GLU	C	462	5.518	5.755	14.941	1.00	67.31	N
ATOM	12090	CA	GLU	C	462	5.213	5.279	16.294	1.00	66.76	C
ATOM	12092	CB	GLU	C	462	4.457	3.943	16.269	1.00	66.38	C
ATOM	12095	CG	GLU	C	462	3.833	3.562	17.614	1.00	66.74	C
ATOM	12098	CD	GLU	C	462	2.325	3.796	17.750	1.00	69.26	C
ATOM	12099	OE1	GLU	C	462	1.587	3.914	16.728	1.00	70.12	O
ATOM	12100	OE2	GLU	C	462	1.840	3.828	18.921	1.00	71.30	O
ATOM	12101	C	GLU	C	462	6.496	5.142	17.143	1.00	66.47	C
ATOM	12102	O	GLU	C	462	7.492	4.587	16.696	1.00	66.02	O
ATOM	12104	N	GLY	C	463	6.454	5.695	18.352	1.00	66.38	N
ATOM	12105	CA	GLY	C	463	7.542	5.590	19.297	1.00	66.62	C
ATOM	12108	C	GLY	C	463	8.801	6.338	18.955	1.00	66.75	C
ATOM	12109	O	GLY	C	463	9.857	6.016	19.447	1.00	67.13	O
ATOM	12111	N	CYS	C	464	8.691	7.348	18.115	1.00	67.75	N
ATOM	12112	CA	CYS	C	464	9.825	8.169	17.752	1.00	67.86	C
ATOM	12114	CB	CYS	C	464	9.634	8.710	16.355	1.00	67.42	C
ATOM	12117	SC	CYS	C	464	11.197	9.330	15.788	1.00	69.17	S
ATOM	12119	C	CYS	C	464	9.993	9.334	18.759	1.00	67.83	C
ATOM	12120	O	CYS	C	464	9.058	10.150	18.903	1.00	67.66	O
ATOM	12122	N	PRO	C	465	11.146	9.421	19.440	1.00	67.97	N
ATOM	12123	CA	PRO	C	465	11.409	10.500	20.401	1.00	68.39	C
ATOM	12125	CB	PRO	C	465	12.908	10.371	20.683	1.00	68.08	C
ATOM	12128	CG	PRO	C	465	13.238	8.975	20.406	1.00	68.19	C
ATOM	12131	CD	PRO	C	465	12.288	8.492	19.355	1.00	67.90	C
ATOM	12134	C	PRO	C	465	11.131	11.930	19.897	1.00	69.79	C
ATOM	12135	O	PRO	C	465	11.483	12.291	18.758	1.00	69.38	O
ATOM	12136	N	GLU	C	466	10.462	12.707	20.755	1.00	71.40	N
ATOM	12137	CA	GLU	C	466	10.374	14.174	20.667	1.00	71.53	C
ATOM	12139	CB	GLU	C	466	10.379	14.769	22.103	1.00	71.76	C
ATOM	12142	CG	GLU	C	466	10.123	16.278	22.199	1.00	72.25	C
ATOM	12145	CD	GLU	C	466	8.677	16.680	21.877	1.00	73.86	C
ATOM	12146	OE1	GLU	C	466	7.817	16.620	22.810	1.00	73.77	O
ATOM	12147	OE2	GLU	C	466	8.404	17.080	20.708	1.00	73.17	O
ATOM	12148	C	GLU	C	466	11.507	14.791	19.813	1.00	71.19	C
ATOM	12149	O	GLU	C	466	11.256	15.308	18.722	1.00	71.29	O
ATOM	12151	N	LYS	C	467	12.744	14.660	20.286	1.00	70.44	N
ATOM	12152	CA	LYS	C	467	13.873	15.383	19.685	1.00	70.16	C
ATOM	12154	CB	LYS	C	467	15.091	15.489	20.653	1.00	70.52	C
ATOM	12157	CG	LYS	C	467	14.897	16.529	21.834	1.00	70.46	C
ATOM	12160	CD	LYS	C	467	16.244	17.098	22.383	1.00	70.57	C
ATOM	12163	CE	LYS	C	467	17.029	16.136	23.315	1.00	69.61	C
ATOM	12166	NZ	LYS	C	467	17.144	16.586	24.724	1.00	67.96	N
ATOM	12170	C	LYS	C	467	14.273	14.842	18.314	1.00	69.43	C
ATOM	12171	O	LYS	C	467	14.567	15.639	17.417	1.00	68.74	O
ATOM	12173	N	VAL	C	468	14.232	13.513	18.164	1.00	69.21	N
ATOM	12174	CA	VAL	C	468	14.552	12.809	16.903	1.00	69.27	C
ATOM	12176	CB	VAL	C	468	14.448	11.229	17.031	1.00	68.89	C
ATOM	12178	CG1	VAL	C	468	14.752	10.519	15.700	1.00	68.40	C
ATOM	12182	CG2	VAL	C	468	15.382	10.659	18.063	1.00	68.24	C
ATOM	12186	C	VAL	C	468	13.648	13.296	15.758	1.00	69.33	C
ATOM	12187	O	VAL	C	468	14.129	13.519	14.671	1.00	69.32	O
ATOM	12189	N	TYR	C	469	12.357	13.468	16.019	1.00	70.46	N
ATOM	12190	CA	TYR	C	469	11.410	13.999	15.027	1.00	70.99	C
ATOM	12192	CB	TYR	C	469	9.949	13.802	15.463	1.00	71.48	C
ATOM	12195	CG	TYR	C	469	8.939	14.134	14.360	1.00	71.27	C
ATOM	12196	CD1	TYR	C	469	8.949	13.412	13.161	1.00	71.53	C
ATOM	12198	CE1	TYR	C	469	8.045	13.698	12.121	1.00	72.46	C
ATOM	12200	CZ	TYR	C	469	7.096	14.708	12.263	1.00	72.16	C
ATOM	12201	OH	TYR	C	469	6.256	14.894	11.183	1.00	71.86	O
ATOM	12203	CE2	TYR	C	469	7.042	15.466	13.455	1.00	71.21	C
ATOM	12205	CD2	TYR	C	469	7.983	15.179	14.500	1.00	71.42	C
ATOM	12207	C	TYR	C	469	11.578	15.467	14.728	1.00	71.93	C
ATOM	12208	O	TYR	C	469	11.388	15.869	13.609	1.00	72.06	O
ATOM	12210	N	GLU	C	470	11.852	16.287	15.734	1.00	73.68	N
ATOM	12211	CA	GLU	C	470	12.160	17.720	15.501	1.00	74.92	C
ATOM	12213	CB	GLU	C	470	12.503	18.436	16.801	1.00	75.20	C
ATOM	12216	CG	GLU	C	470	11.422	18.556	17.878	1.00	76.43	C
ATOM	12219	CD	GLU	C	470	12.030	18.974	19.245	1.00	77.35	C
ATOM	12220	OE1	GLU	C	470	13.208	19.476	19.281	1.00	79.25	O
ATOM	12221	OE2	GLU	C	470	11.341	18.814	20.295	1.00	80.28	O
ATOM	12222	C	GLU	C	470	13.383	17.857	14.583	1.00	74.65	C
ATOM	12223	O	GLU	C	470	13.410	18.735	13.711	1.00	74.84	O
ATOM	12225	N	LEU	C	471	14.379	16.987	14.828	1.00	74.33	N
ATOM	12226	CA	LEU	C	471	15.585	16.853	13.996	1.00	74.11	C
ATOM	12228	CB	LEU	C	471	16.599	15.856	14.604	1.00	74.28	C
ATOM	12231	CG	LEU	C	471	18.068	16.300	14.577	1.00	75.50	C
ATOM	12233	CD	LEU	C	471	18.355	17.503	15.530	1.00	75.50	C
ATOM	12237	CD2	LEU	C	471	18.962	15.098	14.927	1.00	75.06	C
ATOM	12241	C	LEU	C	471	15.224	16.459	12.557	1.00	73.85	C
ATOM	12242	O	LEU	C	471	15.440	17.265	11.626	1.00	74.55	O
ATOM	12244	N	MET	C	472	14.635	15.273	12.373	1.00	72.81	N
ATOM	12245	CA	MET	C	472	14.066	14.865	11.080	1.00	72.36	C
ATOM	12247	CB	MET	C	472	12.905	13.874	11.270	1.00	72.08	C
ATOM	12250	CG	MET	C	472	13.287	12.430	11.308	1.00	71.91	C
ATOM	12253	SD	MET	C	472	11.855	11.396	11.046	1.00	71.34	S
ATOM	12254	CE	MET	C	472	12.366	9.958	11.937	1.00	72.31	C
ATOM	12258	C	MET	C	472	13.516	16.052	10.291	1.00	72.27	C
ATOM	12259	O	MET	C	472	13.913	16.293	9.147	1.00	73.38	O
ATOM	12261	N	ARG	C	473	12.627	16.794	10.951	1.00	71.39	N
ATOM	12262	CA	ARG	C	473	11.841	17.851	10.345	1.00	70.33	C
ATOM	12264	CB	ARG	C	473	10.665	18.194	11.272	1.00	70.31	C
ATOM	12267	CG	ARG	C	473	9.604	17.112	11.314	1.00	70.11	C
ATOM	12270	CD	ARG	C	473	8.584	17.201	10.216	1.00	72.05	C
ATOM	12273	NE	ARG	C	473	7.575	18.243	10.502	1.00	72.85	N
ATOM	12275	CZ	ARG	C	473	7.559	19.508	10.030	1.00	73.03	C
ATOM	12276	NH1	ARG	C	473	8.492	19.989	9.191	1.00	74.44	N
ATOM	12279	NH2	ARG	C	473	6.580	20.323	10.412	1.00	73.45	N
ATOM	12282	C	ARG	C	473	12.645	19.099	10.019	1.00	69.73	C
ATOM	12283	O	ARG	C	473	12.229	19.869	9.150	1.00	68.83	O
ATOM	12285	N	ALA	C	474	13.749	19.309	10.744	1.00	69.65	N
ATOM	12286	CA	ALA	C	474	14.685	20.437	10.502	1.00	70.05	C
ATOM	12288	CB	ALA	C	474	15.608	20.669	11.692	1.00	69.86	C
ATOM	12292	C	ALA	C	474	15.523	20.214	9.248	1.00	70.15	C
ATOM	12293	O	ALA	C	474	15.889	21.175	8.561	1.00	69.64	O
ATOM	12295	N	CYS	C	475	15.840	18.943	8.977	1.00	70.10	N
ATOM	12296	CA	CYS	C	475	16.419	18.546	7.685	1.00	69.60	C
ATOM	12298	CB	CYS	C	475	16.917	17.102	7.703	1.00	69.70	C
ATOM	12301	SG	CYS	C	475	17.878	16.729	9.138	1.00	68.18	S
ATOM	12303	C	CYS	C	475	15.443	18.631	6.547	1.00	69.09	C
ATOM	12304	O	CYS	C	475	15.879	18.750	5.414	1.00	70.18	O
ATOM	12306	N	TRP	C	476	14.153	18.472	6.812	1.00	68.08	N
ATOM	12307	CA	TRP	C	476	13.183	18.593	5.752	1.00	68.22	C
ATOM	12309	CB	TRP	C	476	12.051	17.606	5.937	1.00	67.38	C
ATOM	12312	CG	TRP	C	476	12.453	16.191	6.015	1.00	66.38	C
ATOM	12313	CD1	TRP	C	476	13.592	15.618	5.510	1.00	66.01	C
ATOM	12315	NE1	TRP	C	476	13.594	14.272	5.751	1.00	65.52	N
ATOM	12317	CE2	TRP	C	476	12.435	13.937	6.400	1.00	65.24	C
ATOM	12318	CD2	TRP	C	476	11.685	15.134	6.561	1.00	65.93	C
ATOM	12319	CE3	TRP	C	476	10.426	15.061	7.183	1.00	66.49	C
ATOM	12321	CZ3	TRP	C	476	9.960	13.792	7.628	1.00	66.31	C
ATOM	12323	CH2	TRP	C	476	10.740	12.625	7.448	1.00	65.24	C
ATOM	12325	CZ2	TRP	C	476	11.972	12.681	6.842	1.00	64.81	C
ATOM	12327	C	TRP	C	476	12.654	20.022	5.580	1.00	69.63	C
ATOM	12328	O	TRP	C	476	11.665	20.207	4.866	1.00	69.57	O
ATOM	12330	N	GLN	C	477	13.304	21.035	6.184	1.00	70.75	N
ATOM	12331	CA	GLN	C	477	12.910	22.404	5.933	1.00	71.84	C
ATOM	12333	CB	GLN	C	477	13.539	23.419	6.905	1.00	72.13	C
ATOM	12336	CG	GLN	C	477	12.784	23.544	8.248	1.00	73.41	C
ATOM	12339	CD	GLN	C	477	11.260	23.795	8.093	1.00	73.82	C
ATOM	12340	OE1	GLN	C	477	10.856	24.741	7.418	1.00	73.55	O
ATOM	12341	NE2	GLN	C	477	10.435	22.925	8.690	1.00	72.81	N
ATOM	12344	C	GLN	C	477	13.198	22.736	4.473	1.00	72.57	C
ATOM	12345	O	GLN	C	477	14.325	22.623	4.023	1.00	72.58	O
ATOM	12347	N	TRP	C	478	12.121	23.095	3.769	1.00	73.54	N
ATOM	12348	CA	TRP	C	478	12.055	23.424	2.332	1.00	73.97	C
ATOM	12350	CB	TRP	C	478	10.848	24.347	2.115	1.00	73.47	C
ATOM	12353	CG	TRP	C	478	10.754	24.864	0.756	1.00	73.34	C
ATOM	12354	CD	TRP	C 478	10.940	26.170	0.331	1.00	72.98	C
ATOM	12356	NE1	TRP	C 478	10.756	26.245	−1.027	1.00	72.16	N
ATOM	12358	CE2	TRP	C 478	10.469	24.988	−1.506	1.00	72.89	C
ATOM	12359	CD2	TRP	C 478	10.465	24.099	−0.398	1.00	72.99	C
ATOM	12360	CE3	TRP	C 478	10.177	22.740	−0.620	1.00	72.89	C
ATOM	12362	CZ3	TRP	C 478	9.932	22.302	−1.933	1.00	72.88	C
ATOM	12364	CH2	TRP	C 478	9.952	23.208	−3.012	1.00	72.80	C
ATOM	12366	CZ2	TRP	C 478	10.218	24.550	−2.820	1.00	73.06	C
ATOM	12368	C	TRP	C	478	13.276	24.124	1.754	1.00	74.71	C
ATOM	12369	O	TRP	C	478	13.869	23.681	0.754	1.00	75.24	O
ATOM	12371	N	ASN	C	479	13.629	25.228	2.395	1.00	75.11	N
ATOM	12372	CA	ASN	C	479	14.726	26.036	1.937	1.00	75.48	C
ATOM	12374	CB	ASN	C	479	14.473	27.488	2.355	1.00	75.37	C
ATOM	12377	CG	ASN	C	479	15.418	28.449	1.731	1.00	74.29	C
ATOM	12378	OD1	ASN	C	479	15.844	28.291	0.590	1.00	73.05	O
ATOM	12379	ND2	ASN	C	479	15.758	29.473	2.481	1.00	73.74	N
ATOM	12382	C	ASN	C	479	16.024	25.437	2.539	1.00	75.90	C
ATOM	12383	O	ASN	C	479	16.097	25.337	3.770	1.00	75.97	O
ATOM	12385	N	PRO	C	480	17.000	24.990	1.708	1.00	76.07	N
ATOM	12386	CA	PRO	C	480	18.353	24.611	2.187	1.00	76.06	C
ATOM	12388	CB	PRO	C	480	19.233	24.807	0.934	1.00	75.67	C
ATOM	12391	CG	PRO	C	480	18.345	24.568	−0.213	1.00	75.45	C
ATOM	12394	CD	PRO	C	480	16.914	24.769	0.246	1.00	76.08	C
ATOM	12397	C	PRO	C	480	18.926	25.437	3.341	1.00	76.36	C
ATOM	12398	O	PRO	C	480	19.365	24.847	4.340	1.00	75.80	O
ATOM	12399	N	SER	C	481	18.869	26.777	3.199	1.00	76.68	N
ATOM	12400	CA	SER	C	481	19.385	27.743	4.191	1.00	77.15	C
ATOM	12402	CB	SER	C	481	18.914	29.166	3.891	1.00	77.22	C
ATOM	12405	OG	SER	C	481	19.306	29.598	2.605	1.00	77.53	O
ATOM	12407	C	SER	C	481	18.992	27.420	5.632	1.00	77.64	C
ATOM	12408	O	SER	C	481	19.786	27.634	6.551	1.00	77.97	0
ATOM	12410	N	ASP	C	482	17.767	26.911	5.806	1.00	78.01	N
ATOM	12411	CA	ASP	C	482	17.201	26.556	7.128	1.00	78.31	C
ATOM	12413	CB	ASP	C	482	15.763	25.992	7.004	1.00	78.82	C
ATOM	12416	CG	ASP	C	482	14.806	26.925	6.261	1.00	80.70	C
ATOM	12417	OD1	ASP	C	482	14.795	28.169	6.514	1.00	79.60	O
ATOM	12418	OD2	ASP	C	482	14.036	26.458	5.385	1.00	84.01	0
ATOM	12419	C	ASP	C	482	18.013	25.490	7.858	1.00	77.92	C
ATOM	12420	O	ASP	C	482	18.431	25.692	8.994	1.00	78.44	0
ATOM	12422	N	ARG	C	483	18.263	24.391	7.152	1.00	77.04	N
ATOM	12423	CA	ARG	C	483	18.598	23.096	7.739	1.00	76.48	C
ATOM	12425	CB	ARG	C	483	18.844	22.077	6.613	1.00	76.55	C
ATOM	12428	CG	ARG	C	483	17.615	21.728	5.743	1.00	76.73	C
ATOM	12431	CD	ARG	C	483	17.972	21.022	4.423	1.00	77.29	C
ATOM	12434	NE	ARG	C	483	16.899	21.219	3.455	1.00	78.39	N
ATOM	12436	CZ	ARG	C	483	17.019	21.221	2.116	1.00	79.19	C
ATOM	12437	NH1	ARG	C	483	18.171	20.962	1.501	1.00	78.83	N
ATOM	12440	NH2	ARG	C	483	15.934	21.472	1.376	1.00	79.47	N
ATOM	12443	C	ARG	C	483	19.816	23.131	8.649	1.00	75.73	C
ATOM	12444	O	ARG	C	483	20.659	23.998	8.488	1.00	75.54	O
ATOM	12446	N	PRO	C	484	19.940	22.183	9.579	1.00	75.37	N
ATOM	12447	CA	PRO	C	484	21.086	22.173	10.472	1.00	75.01	C
ATOM	12449	CB	PRO	C	484	20.677	21.181	11.564	1.00	75.00	C
ATOM	12452	CG	PRO	C	484	19.846	20.200	10.856	1.00	75.41	C
ATOM	12455	CD	PRO	C	484	19.065	21.021	9.845	1.00	75.69	C
ATOM	12458	C	PRO	C	484	22.307	21.663	9.736	1.00	74.47	C
ATOM	12459	O	PRO	C	484	22.203	21.202	8.610	1.00	74.36	O
ATOM	12460	N	SER	C	485	23.449	21.783	10.389	1.00	74.07	N
ATOM	12461	CA	SER	C	485	24.686	21.199	9.930	1.00	73.51	C
ATOM	12463	CB	SER	C	485	25.881	22.030	10.419	1.00	73.50	C
ATOM	12466	OG	SER	C	485	25.722	22.407	11.770	1.00	72.87	O
ATOM	12468	C	SER	C	485	24.746	19.802	10.496	1.00	73.26	C
ATOM	12469	O	SER	C	485	24.110	19.507	11.502	1.00	72.75	O
ATOM	12471	N	PHE	C	486	25.526	18.950	9.839	1.00	73.47	N
ATOM	12472	CA	PHE	C	486	25.917	17.650	10.392	1.00	73.80	C
ATOM	12474	CB	PHE	C	486	26.637	16.777	9.360	1.00	73.84	C
ATOM	12477	CG	PHE	C	486	25.704	16.128	8.370	1.00	74.33	C
ATOM	12478	CD1	PHE	C	486	24.739	15.207	8.804	1.00	74.58	C
ATOM	12480	CE1	PHE	C	486	23.874	14.586	7.900	1.00	73.37	C
ATOM	12482	CZ	PHE	C	486	23.957	14.870	6.565	1.00	72.96	C
ATOM	12484	CE2	PHE	C	486	24.915	15.779	6.109	1.00	73.34	C
ATOM	12486	CD2	PHE	C	486	25.787	16.405	7.011	1.00	73.39	C
ATOM	12488	C	PHE	C	486	26.776	17.767	11.631	1.00	74.22	C
ATOM	12489	O	PHE	C	486	26.900	16.777	12.371	1.00	74.51	O
ATOM	12491	N	ALA	C	487	27.404	18.943	11.809	1.00	74.41	N
ATOM	12492	CA	ALA	C	487	27.946	19.402	13.099	1.00	74.38	C
ATOM	12494	CB	ALA	C	487	28.663	20.742	12.910	1.00	74.38	C
ATOM	12498	C	ALA	C	487	26.884	19.511	14.213	1.00	74.17	C
ATOM	12499	O	ALA	C	487	27.055	18.956	15.294	1.00	73.60	O
ATOM	12501	N	GLU	C	488	25.796	20.224	13.934	1.00	74.48	N
ATOM	12502	CA	GLU	C	488	24.611	20.232	14.816	1.00	75.02	C
ATOM	12504	CB	GLU	C	488	23.537	21.228	14.299	1.00	75.18	C
ATOM	12507	CG	GLU	C	488	23.884	22.709	14.492	1.00	75.87	C
ATOM	12510	CD	GLU	C	488	23.055	23.678	13.633	1.00	75.88	C
ATOM	12511	OE1	GLU	C	488	21.796	23.548	13.591	1.00	75.64	O
ATOM	12512	OE2	GLU	C	488	23.674	24.595	13.016	1.00	76.33	O
ATOM	12513	C	GLU	C	488	23.981	18.825	15.021	1.00	75.06	C
ATOM	12514	O	GLU	C	488	23.632	18.458	16.146	1.00	74.98	O
ATOM	12516	N	ILE	C	489	23.862	18.046	13.944	1.00	75.01	N
ATOM	12517	CA	ILE	C	489	23.168	16.743	13.985	1.00	75.07	C
ATOM	12519	CB	ILE	C	489	22.870	16.224	12.523	1.00	75.14	C
ATOM	12521	CG1	ILE	C	489	21.895	17.158	11.784	1.00	74.44	C
ATOM	12524	CD1	ILE	C	489	22.041	17.116	10.282	1.00	74.50	C
ATOM	12528	CG2	ILE	C	489	22.303	14.788	12.512	1.00	75.22	C
ATOM	12532	C	ILE	C	489	23.936	15.704	14.833	1.00	75.35	C
ATOM	12533	O	ILE	C	489	23.339	14.968	15.598	1.00	75.25	O
ATOM	12535	N	HIS	C	490	25.250	15.647	14.687	1.00	75.80	N
ATOM	12536	CA	HIS	C	490	26.088	14.850	15.583	1.00	76.30	C
ATOM	12538	CB	HIS	C	490	27.563	14.905	15.147	1.00	76.62	C
ATOM	12541	CG	HIS	C	490	28.450	13.918	15.855	1.00	77.40	C
ATOM	12542	ND1	HIS	C	490	28.200	12.559	15.865	1.00	78.16	N
ATOM	12544	CE1	HIS	C	490	29.142	11.946	16.562	1.00	77.55	C
ATOM	12546	NE2	HIS	C	490	30.006	12.852	16.982	1.00	77.45	N
ATOM	12548	CD2	HIS	C	490	29.596	14.093	16.557	1.00	77.25	C
ATOM	12550	C	HIS	C	490	25.976	15.328	17.033	1.00	76.29	C
ATOM	12551	O	HIS	C	490	26.026	14.510	17.949	1.00	76.24	O
ATOM	12553	N	GLN	C	491	25.831	16.641	17.232	1.00	76.39	N
ATOM	12554	CA	GLN	C	491	25.763	17.228	18.586	1.00	76.44	C
ATOM	12556	CB	GLN	C	491	25.732	18.773	18.542	1.00	76.44	C
ATOM	12559	CG	GLN	C	491	25.997	19.472	19.858	1.00	76.35	C
ATOM	12562	CD	GLN	C	491	27.330	19.112	20.475	1.00	76.73	C
ATOM	12563	OE1	GLN	C	491	27.474	19.155	21.689	1.00	77.27	O
ATOM	12564	NE2	GLN	C	491	28.305	18.751	19.646	1.00	77.64	N
ATOM	12567	C	GLN	C	491	24.556	16.718	19.354	1.00	76.13	C
ATOM	12568	O	GLN	C	491	24.700	16.209	20.460	1.00	76.22	O
ATOM	12570	N	ALA	C	492	23.388	16.853	18.738	1.00	75.69	N
ATOM	12571	CA	ALA	C	492	22.165	16.288	19.250	1.00	75.71	C
ATOM	12573	CB	ALA	C	492	21.039	16.526	18.278	1.00	75.71	C
ATOM	12577	C	ALA	C	492	22.322	14.795	19.507	1.00	76.10	C
ATOM	12578	O	ALA	C	492	22.096	14.329	20.630	1.00	76.68	O
ATOM	12580	N	PHE	C	493	22.746	14.061	18.486	1.00	76.26	N
ATOM	12581	CA	PHE	C	493	22.816	12.596	18.566	1.00	76.75	C
ATOM	12583	CB	PHE	C	493	22.950	11.929	17.172	1.00	76.94	C
ATOM	12586	CG	PHE	C	493	21.636	11.535	16.567	1.00	76.69	C
ATOM	12587	CD1	PHE	C	493	20.961	10.400	17.042	1.00	78.13	C
ATOM	12589	CE1	PHE	C	493	19.711	10.024	16.520	1.00	77.96	C
ATOM	12591	CZ	PHE	C	493	19.144	10.772	15.515	1.00	77.10	C
ATOM	12593	CE2	PHE	C	493	19.810	11.913	15.040	1.00	77.24	C
ATOM	12595	CD2	PHE	C	493	21.049	12.289	15.562	1.00	76.21	C
ATOM	12597	C	PHE	C	493	23.880	12.049	19.506	1.00	76.93	C
ATOM	12598	O	PHE	C	493	23.703	10.939	19.989	1.00	76.69	O
ATOM	12600	N	GLU	C	494	24.973	12.790	19.745	1.00	77.61	N
ATOM	12601	CA	GLU	C	494	25.955	12.420	20.801	1.00	77.86	C
ATOM	12603	CB	GLU	C	494	27.312	13.194	20.695	1.00	77.92	C
ATOM	12606	CG	GLU	C	494	28.551	12.383	21.147	1.00	78.10	C
ATOM	12609	CD	GLU	C	494	29.859	13.185	21.333	1.00	78.45	C
ATOM	12610	OE1	GLU	C	494	29.861	14.231	22.018	1.00	79.49	O
ATOM	12611	OE2	GLU	C	494	30.924	12.752	20.831	1.00	78.61	O
ATOM	12612	C	GLU	C	494	25.261	12.606	22.175	1.00	77.87	C
ATOM	12613	O	GLU	C	494	25.228	11.666	22.977	1.00	77.35	O
ATOM	12615	N	THR	C	495	24.658	13.787	22.388	1.00	78.20	N
ATOM	12616	CA	THR	C	495	23.856	14.098	23.593	1.00	78.66	C
ATOM	12618	CB	THR	C	495	23.254	15.537	23.530	1.00	78.21	C
ATOM	12620	OG1	THR	C	495	24.249	16.469	23.101	1.00	77.25	O
ATOM	12622	CG2	THR	C	495	22.871	16.045	24.907	1.00	77.26	C
ATOM	12626	C	THR	C	495	22.747	13.060	23.861	1.00	79.40	C
ATOM	12627	O	THR	C	495	22.860	12.310	24.836	1.00	79.36	O
ATOM	12629	N	MET	C	496	21.733	12.980	22.983	1.00	80.22	N
ATOM	12630	CA	MET	C	496	20.602	12.025	23.134	1.00	81.03	C
ATOM	12632	CB	MET	C	496	19.734	11.959	21.877	1.00	81.25	C
ATOM	12635	CG	MET	C	496	18.940	13.203	21.537	1.00	82.06	C
ATOM	12638	SD	MET	C	496	17.636	12.796	20.286	1.00	82.93	S
ATOM	12639	CE	MET	C	496	18.091	13.928	18.988	1.00	82.16	C
ATOM	12643	C	MET	C	496	21.005	10.583	23.441	1.00	81.63	C
ATOM	12644	O	MET	C	496	20.317	9.902	24.181	1.00	81.71	O
ATOM	12646	N	PHE	C	497	22.102	10.133	22.843	1.00	82.65	N
ATOM	12647	CA	PHE	C	497	22.613	8.762	23.010	1.00	83.43	C
ATOM	12649	CB	PHE	C	497	23.761	8.518	22.025	1.00	83.60	C
ATOM	12652	CG	PHE	C	497	24.385	7.164	22.131	1.00	83.70	C
ATOM	12653	CD1	PHE	C	497	23.603	6.015	21.985	1.00	83.53	C
ATOM	12655	CE1	PHE	C	497	24.180	4.748	22.055	1.00	83.37	C
ATOM	12657	CZ	PHE	C	497	25.554	4.622	22.248	1.00	83.54	C
ATOM	12659	CE2	PHE	C	497	26.355	5.773	22.397	1.00	83.62	C
ATOM	12661	CD2	PHE	C	497	25.764	7.032	22.336	1.00	84.04	C
ATOM	12663	C	PHE	C	497	23.063	8.396	24.432	1.00	83.69	C
ATOM	12664	O	PHE	C	497	22.361	7.635	25.092	1.00	83.94	O
ATOM	12666	N	GLN	C	498	24.213	8.917	24.890	1.00	83.93	N
ATOM	12667	CA	GLN	C	498	24.795	8.523	26.211	1.00	83.93	C
ATOM	12669	CB	GLN	C	498	26.308	8.849	26.298	1.00	84.04	C
ATOM	12672	CG	GLN	C	498	26.682	10.349	26.294	1.00	83.90	C
ATOM	12675	CD	GLN	C	498	28.121	10.635	25.841	1.00	83.20	C
ATOM	12676	OE1	GLN	C	498	28.516	10.274	24.737	1.00	80.32	O
ATOM	12677	NE2	GLN	C	498	28.886	11.309	26.689	1.00	82.58	N
ATOM	12680	C	GLN	C	498	24.009	9.016	27.459	1.00	84.24	C
ATOM	12681	O	GLN	C	498	24.255	8.538	28.575	1.00	84.05	O
ATOM	12683	N	GLN	C	499	23.082	9.963	27.262	1.00	84.51	N
ATOM	12684	CA	GLN	C	499	21.974	10.190	28.200	1.00	84.91	C
ATOM	12686	CB	GLN	C	499	21.136	11.414	27.819	1.00	84.75	C
ATOM	12689	CG	GLU	C	499	21.851	12.736	28.050	1.00	84.75	C
ATOM	12692	CD	GLU	C	499	20.996	13.945	27.686	1.00	84.95	C
ATOM	12693	OE1	GLU	C	499	20.417	13.974	26.573	1.00	86.01	O
ATOM	12694	OE2	GLU	C	499	20.907	14.884	28.504	1.00	83.89	O
ATOM	12695	C	GLU	C	499	21.080	8.954	28.247	1.00	85.30	C
ATOM	12696	O	GLU	C	499	20.837	8.413	29.326	1.00	85.69	O
ATOM	12698	N	SER	C	500	20.615	8.514	27.078	1.00	85.74	N
ATOM	12699	CA	SER	C	500	19.830	7.265	26.939	1.00	86.35	C
ATOM	12701	CB	SER	C	500	19.173	7.153	25.534	1.00	86.69	C
ATOM	12704	OG	SER	C	500	18.794	5.823	25.197	1.00	87.87	O
ATOM	12706	C	SER	C	500	20.697	6.044	27.233	1.00	86.23	C
ATOM	12707	O	SER	C	500	20.791	5.621	28.378	1.00	86.31	O
ATOM	12709	O27	INH	I	501	50.633	14.353	58.105	1.00	47.28	O
ATOM	12710	C26	INH	I	501	50.065	15.076	58.915	1.00	47.55	C
ATOM	12711	N24	INH	I	501	48.744	15.160	59.089	1.00	47.40	N
ATOM	12713	C21	INH	I	501	48.278	16.088	60.124	1.00	47.21	C
ATOM	12716	C9	INH	I	501	49.607	16.598	60.592	1.00	47.20	C
ATOM	12717	C10	INH	I	501	49.830	17.559	61.607	1.00	47.36	C
ATOM	12718	C2	INH	I	501	51.202	17.896	61.884	1.00	47.25	C
ATOM	12719	C8	INH	I	501	50.655	16.010	59.876	1.00	47.56	C
ATOM	12720	C7	INH	I	501	52.013	16.352	60.146	1.00	47.51	C
ATOM	12721	C3	INH	I	501	52.224	17.321	61.199	1.00	47.43	C
ATOM	12722	C6	INH	I	501	53.330	15.986	59.668	1.00	47.48	C
ATOM	12723	C28	INH	I	501	53.690	15.014	58.565	1.00	47.38	C
ATOM	12726	C31	INH	I	501	55.197	14.809	58.362	1.00	46.70	C
ATOM	12729	C34	INH	I	501	56.003	16.072	58.728	1.00	46.96	C
ATOM	12732	C37	INH	I	501	55.723	16.581	60.155	1.00	47.49	C
ATOM	12735	C5	INH	I	501	54.233	16.697	60.372	1.00	47.31	C
ATOM	12736	N4	INH	I	501	53.599	17.5O5	61.275	1.00	47.53	N
ATOM	12737	C40	INH	I	501	54.292	18.373	62.200	1.00	47.38	C
ATOM	12739	C48	INH	I	501	54.785	19.665	61.519	1.00	46.93	C
ATOM	12742	C46	INH	I	501	54.362	20.848	62.393	1.00	47.05	C
ATOM	12744	NS1	INH	I	501	54.763	22.190	61.909	1.00	48.18	N
ATOM	12746	C53	INH	I	501	56.125	22.499	61.406	1.00	48.59	C
ATOM	127S0	C44	INH	I	501	52.842	20.770	62.664	1.00	47.40	C
ATOM	12752	O57	INH	I	501	51.888	21.195	61.632	1.00	45.70	O
ATOM	12753	C58	INH	I	501	51.800	20.708	60.301	1.00	42.85	C
ATOM	12757	C43	INH	I	501	52.442	19.448	63.439	1.00	47.56	C
ATOM	12758	O42	INH	I	501	53.515	18.461	63.411	1.00	45.24	O
ATOM	12759	C62	INH	I	501	52.390	19.715	64.974	1.00	47.79	C
ATOM	12763	N1	INH	I	501	51.174	18.860	62.912	1.00	47.89	N
ATOM	12764	C12	INH	I	501	49.815	19.129	63.256	1.00	47.31	C
ATOM	12765	C11	INH	I	501	48.994	18.348	62.500	1.00	47.60	C
ATOM	12766	C19	INH	I	501	47.577	18.361	62.613	1.00	47.54	C
ATOM	12768	C17	INH	I	501	46.986	19.219	63.567	1.00	47.59	C
ATOM	12770	C15	INH	I	501	47.814	20.022	64.375	1.00	47.42	C
ATOM	12772	C13	INH	I	501	49.219	19.978	64.214	1.00	47.09	C
ATOM	12774	O27	INH	J	501	31.430	6.054	23.367	1.00	65.83	O
ATOM	12775	C26	INH	J	501	30.619	5.142	23.223	1.00	65.94	C
ATOM	12776	N24	INH	J	501	30.418	4.380	22.131	1.00	65.75	N
ATOM	12778	C21	INH	J	501	29.363	3.368	22.235	1.00	65.64	C
ATOM	12781	C9	INH	J	501	28.946	3.650	23.658	1.00	65.97	C
ATOM	12782	C10	INH	J	501	27.927	3.002	24.392	1.00	65.87	C
ATOM	12783	C2	INH	J	501	27.699	3.458	25.741	1.00	65.78	C
ATOM	12784	C8	INH	J	501	29.680	4.697	24.228	1.00	66.06	C
ATOM	1278S	C7	INH	J	501	29.473	5.161	25.562	1.00	65.85	C
ATOM	12786	C3	INH	J	501	28.431	4.475	26.290	1.00	65.75	C
ATOM	12787	C6	INH	J	501	30.017	6.167	26.456	1.00	65.73	C
ATOM	12788	C28	INH	J	501	31.121	7.174	26.228	1.00	65.76	C
ATOM	12791	C31	INH	J	501	31.413	8.124	27.424	1.00	66.61	C
ATOM	12794	C34	INH	J	501	30.214	8.311	28.377	1.00	66.11	C
ATOM	12797	C37	INH	J	501	29.605	6.968	28.813	1.00	65.84	C
ATOM	12800	C5	INH	J	501	29.326	6.082	27.612	1.00	65.78	C
ATOM	12801	N4	INH	J	501	28.370	5.096	27.533	1.00	65.85	N
ATOM	12802	C40	INH	J	501	27.535	4.687	28.654	1.00	65.93	C
ATOM	12804	C48	INH	J	501	26.385	5.605	29.134	1.00	66.61	C
ATOM	12807	C46	INH	J	501	25.090	4.773	29.114	1.00	68.12	C
ATOM	12809	N51	INH	J	501	23.828	5.541	29.276	1.00	70.21	N
ATOM	12811	C53	INH	J	501	23.236	5.886	30.583	1.00	70.99	C
ATOM	12815	C44	INH	J	501	25.082	4.032	27.776	1.00	67.83	C
ATOM	12817	O57	INH	J	501	25.080	5.052	26.758	1.00	69.18	O
ATOM	12818	C58	INH	J	501	24.560	4.758	25.465	1.00	71.16	C
ATOM	12822	C43	INH	J	501	26.159	2.889	27.624	1.00	66.11	C
ATOM	12823	O42	INH	J	501	27.265	3.274	28.459	1.00	64.71	O
ATOM	12824	C62	INH	J	501	25.767	1.588	28.354	1.00	66.69	C
ATOM	12828	N1	INH	J	501	26.659	2.665	26.247	1.00	65.99	N
ATOM	12829	C12	INH	J	501	26.251	1.760	25.235	1.00	65.93	C
ATOM	12830	C11	INH	J	501	27.011	1.935	24.122	1.00	65.86	C
ATOM	12831	C19	INH	J	501	26.855	1.173	22.927	1.00	66.04	C
ATOM	12833	C17	INH	J	501	25.863	0.151	22.866	1.00	65.95	C
ATOM	12835	C15	INH	J	501	25.063	−0.078	24.014	1.00	66.05	C
ATOM	12837	C13	INH	J	501	25.255	0.728	25.186	1.00	66.17	C
ATOM	12839	O27	INH	K	501	43.601	2.446	9.301	1.00	77.97	O
ATOM	12840	C26	INH	K	501	43.897	1.265	9.367	1.00	78.00	C
ATOM	12841	N24	INH	K	501	43.794	0.503	10.446	1.00	77.96	N
ATOM	12843	C21	INH	K	501	44.213	−0.892	10.274	1.00	78.01	C
ATOM	12846	C9	INH	K	501	44.615	−0.853	8.822	1.00	78.18	C
ATOM	12847	C10	INH	K	501	45.134	−1.918	8.017	1.00	78.28	C
ATOM	12848	C2	INH	K	501	45.446	−1.616	6.640	1.00	78.12	C
ATOM	12849	C8	INH	K	501	44.417	0.425	8.307	1.00	78.13	C
ATOM	12850	C7	INH	K	501	44.728	0.735	6.960	1.00	78.08	C
ATOM	12851	C3	INH	K	501	45.250	−0.354	6.160	1.00	77.92	C
ATOM	128S2	C6	INH	K	501	44.663	1.901	6.098	1.00	78.20	C
ATOM	128S3	C28	INH	K	501	44.195	3.321	6.391	1.00	78.22	C
ATOM	12856	C31	INH	K	501	44.099	4.248	5.162	1.00	78.11	C
ATOM	12859	C34	INH	K	501	45.265	3.941	4.212	1.00	78.58	C
ATOM	12862	C37	INH	K	501	45.184	2.479	3.721	1.00	78.23	C
ATOM	1286S	C5	INH	K	501	45.115	1.515	4.893	1.00	78.13	C
ATOM	12866	N4	INH	K	501	45.483	0.183	4.908	1.00	78.01	N
ATOM	12867	C40	INH	K	501	45.973	−0.554	3.749	1.00	78.06	C
ATOM	12869	C48	INH	K	501	47.444	−0.321	3.349	1.00	77.48	C
ATOM	12872	C46	INH	K	501	48.109	−1.688	3.091	1.00	77.40	C
ATOM	12874	N51	INH	K	501	49.532	−1.613	2.693	1.00	76.83	N
ATOM	12876	C53	INH	K	501	49.991	−1.553	1.286	1.00	76.02	C
ATOM	12880	C44	INH	K	501	47.890	−2.661	4.287	1.00	77.97	C
ATOM	12882	O57	INH	K	501	48.747	−2.548	5.462	1.00	78.78	O
ATOM	12883	C58	INH	K	501	49.004	−1.304	6.139	1.00	78.56	C
ATOM	12887	C43	INH	K	501	46.362	−2.896	4.617	1.00	78.08	C
ATOM	12888	O42	INH	K	501	45.574	−1.935	3.867	1.00	78.81	O
ATOM	12889	C62	INH	K	501	45.792	−4.164	3.906	1.00	77.58	C
ATOM	12893	N1	INH	K	501	45.942	−2.807	6.050	1.00	78.18	N
ATOM	12894	C12	INH	K	501	45.935	−3.816	7.036	1.00	78.13	C
ATOM	12895	C11	INH	K	501	45.458	−3.313	8.208	1.00	78.12	C
ATOM	12896	C19	INH	K	501	45.334	−4.091	9.380	1.00	78.17	C
ATOM	12898	C17	INH	K	501	45.719	−5.454	9.337	1.00	78.18	C
ATOM	12900	C15	INH	K	501	46.213	−6.008	8.130	1.00	78.05	C
ATOM	12902	C13	INH	K	501	46.324	−5.193	6.985	1.00	78.09	C
ATOM	12904	OW0	HOH	W	1	57.692	14.791	31.508	1.00	41.12	O
ATOM	12907	OW0	HOH	W	3	28.042	8.415	−3.283	1.00	59.59	O
ATOM	12910	OW0	NOH	W	4	22.748	−4.409	−8.825	1.00	75.73	O
ATOM	12913	OW0	HOH	W	5	56.632	35.487	64.325	1.00	33.00	O
ATOM	12916	OW0	HOH	W	7	66.942	23.762	47.746	1.00	30.02	O
ATOM	12919	OW0	HOH	W	8	21.929	26.143	5.046	1.00	70.15	O
ATOM	12922	OW0	HOH	W	9	40.405	38.256	40.391	1.00	43.52	O
ATOM	12925	OW0	HOH	W	13	43.665	20.198	63.123	1.00	45.69	O
ATOM	12928	OW0	HOH	W	14	0.193	20.597	3.471	1.00	53.03	O
ATOM	12931	OW0	HOH	W	16	53.621	7.095	−11.697	1.00	60.56	O
ATOM	12934	OW0	HOH	W	17	22.336	11.823	0.006	1.00	39.36	O
ATOM	12937	OW0	HOH	W	18	57.603	27.959	35.248	1.00	51.37	O
ATOM	12940	OW0	HOH	W	19	38.197	44.115	47.189	1.00	53.19	O
ATOM	12943	OW0	HOH	W	24	12.584	7.112	−4.961	1.00	53.80	O
ATOM	12946	OW0	HOH	W	25	36.268	42.784	58.457	1.00	56.23	O
ATOM	12949	OW0	HOH	W	26	48.815	45.938	45.437	1.00	38.06	O
ATOM	12952	OW0	HOH	W	28	50.349	38.734	70.174	1.00	51.33	O
ATOM	12955	OW0	HOH	W	29	43.332	33.410	75.800	1.00	65.57	O
ATOM	12958	OW0	HOH	W	30	40.879	−10.564	17.504	1.00	68.76	O

EXAMPLE 3

Identification and Design of Specific Inhibitors to c-Abl by Virtual Screening

Using the three dimensional information provided herein, in whole or in part, and conventional techniques of molecular modeling and/or molecular replacement, one can design a specific inhibitor of c-Abl which does not bind to other tyrosine kinases. This may be achieved, e.g., by generation of a model structure for high-throughput docking (HTD).

Generation of the Model Structure for HTD

The program ICM v3.0-25d [see Abagyan and Totrov, Curr Opin Chem Biol, Vol. 5, pp. 375-382 (2001)] is used for creation of the HTD model from a pdb file containing the 2.8 Å resolution structure of human c-Abl kinase co-crystallized with Compound A described in Table 6. The pdb file is read into ICM and all water molecules are deleted. The monomer of a c-Abl kinase (chain B) in the pdb file containing an inhibitor (chain I) bound to the ATP binding site is selected as the model for HTD. The remaining monomers (chains A and C) and inhibitors (chains J and K) are deleted. Hydrogen atoms are added to the remaining c-Abl/inhibitor complex and their coordinates are optimized using ICM. The resulting complex is converted to an ICM-formatted object in preparation of the receptor for HTD. The binding site is defined by selecting all residues of c-Abl kinase with any atoms within 5.0 Å of the inhibitor. The size and location of the box used to define the volume of the electrostatic maps for docking is refined manually in order to focus on the ATP binding site. The electrostatic maps are generated using a grid cell size of 0.5 Å.

Testing the Accuracy of the Receptor Docking Model in ICM

A critical means of assessing the accuracy of HTD algorithms is their ability to reproduce experimentally determined binding poses for compounds which bind to the active site of the receptor. The crystallographically determined coordinates of the ligand, Compound A are extracted from the complex structure used to generate the docking model. Covalent bonds are edited interactively in ICM to generate correct connectivity and bond order. Hydrogen atoms are then added and partial charges are assigned. Docking is carried out against the receptor model through the graphical user interface. The resulting docked structure closely matched the crystallographically determined crystal structure, yielding an RMSD of 0.55 Å. As a result, the receptor model is judged to be sufficiently accurate to proceed with HTD on large databases.

Pre-Processing of the Compound Databases for HTD

The Available Chemicals Directory (ACD) (MDL Information Systems, Inc. Available Chemicals Directory, 2003. San Leandro, Calif.) and a proprietary Novartis Corporate Database (CDB) are screened for compounds with potential inhibitory activity against human c-Abl kinase. These compounds are filtered so that salts are stripped and duplicates are removed. Unity v4.3 (Tripos, Inc. 2003. St. Louis, Mo.) is then used to filter compounds which are either present in mixtures, contain metals, are isotopes, do not possess any carbon atoms, have a ClogP greater than 5.0, or do not possess a molecular weight between 50 Daltons and 500 Daltons. This results in a database containing 140,219 compounds from the ACD and 686,100 compounds from the CDB. The CDB is further processed with Pipeline Pilot v3.0 (Scitegic, Inc. Pipeline Pilot 3.0 2003, San Diego, Calif.) to generate a maximally diverse subset containing 343,050 compounds.

HTD with ICM

All HTD calculations are carried out on a 92 processor Linux cluster consisting of 46 dual-processor Xeon CPUs (2.4 GHz) using the Linux 2.4.20 operating system. The ACD and CDB databases are submitted to docking with ICM against the receptor model of human c-Abl kinase. Partial charges are assigned to the atoms of each compound at the time of docking within ICM. Only the top scoring pose for each compound is retained. The resulting docked poses are written to binary output files and the scores for each compound are written to text files.

Analysis of HTD Results

The top scoring compounds from each database are taken to be those with a score corresponding to three standard deviations below the mean score. This resulted in 76 compounds and 724 compounds selected from the ACD and CDB, respectively. Extended connectivity fingerprints (ECFPs) (Scitegic, Inc. Pipeline Pilot 3.0 2003, San Diego, Calif.) with a neighborhood size of 6 are calculated, as implemented in Pipeline Pilot v3.0. The top scoring compounds from each database are clustered according to their ECFPs in Pipeline Pilot, yielding a total of 4 clusters and 37 clusters for the ACD and CDB, respectively. The top 200 scoring compounds from the combined ACD and CDB datasets are evaluated interactively using molecular graphics, and 48 were selected for further testing.

The top scoring poses are evaluated interactively using molecular graphics to select those compounds which formed favorable intermolecular hydrogen bonds and van der Waals interactions with the c-Abl kinase receptor model, as well as to eliminate compounds containing cis-amides and non-aromatic tautomers. Compounds are also selected for desirable drug-like properties, such as size, lipophilicity and chemical stability. The resulting “hit” compounds are confirmed as leads for drug optimization, by their in vitro evaluation in a test for activity against c-Abl protein tyrosine kinase. The test is conducted as a filter binding assay as follows: The His-tagged kinase domain of c-Abl is cloned and expressed in the baculovirus/Sf9 system. See Bhat et al., J Biol Chem, Vol. 27, pp. 16170-16175 (1997). A protein of 37 kD (c-Abl kinase) is purified by a two-step procedure over a Cobalt metal chelate column followed by an anion exchange column with a yield of 1-2 mg/L of Sf9 cells. The purity of the c-Abl kinase is >90% as judged by SDS-PAGE after Coomassie blue staining. The assay contains: c-Abl kinase (50 ng), 20 mM Tris.HCl, pH 7.5, 10 mM MgCl₂, 10 μM Na₃VO₄, 1 mM DTT and 0.06 μCi/assay [³²P]-ATP (5 μM ATP) using 30 μg/mL poly-Ala,Glu,Lys,Tyr-6:2:5:1 (Poly-AEKY, Sigma P1152) in the presence of 1% DMSO, total volume of 30 μL. Reactions are terminated by adding 10 μL of 250 mM EDTA, and 30 μL of the reaction mixture is transferred onto Immobilon-PVDF membrane (Millipore, Bedford, Mass., USA) previously soaked for 5 minutes with methanol, rinsed with water, then soaked for 5 minutes with 0.5% H₃PO₄ and mounted on vacuum manifold with disconnected vacuum source. After spotting all samples, vacuum is connected and each well-rinsed with 200 μL 0.5% H₃PO₄. Membranes are removed and washed on a shaker with 0.5% H₃PO₄ (4 times) and once with ethanol. Membranes are counted after drying at ambient temperature, mounting in Packard TopCount 96-well frame, and addition of 10 μL/well of Microscint™ (Packard). The activity of the compounds is quantified as IC₅₀ and IC₉₀ values, as determined from their dose response curves by graphical extrapolation. Thus, IC₅₀ values are determined by linear regression analysis of the percentages for the inhibition of each compound in at least four concentrations (as a rule 0.01, 0.1, 1.0 and 10 mol).

Results

Results of virtual screening has identified at least three specific inhibitors of c-Abl kinase. One of these 2-[[2-[3-[4-amino-5-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-7-yl]phenoxy]ethyl]amino]-ethanol, is disclosed in WO 97/49706 and is known to be a tyrosine kinase inhibitor, thus validating the methods disclosed herein.

Claims

1. A crystal of c-Abl comprising unit cell dimensions: a=182.6 Å, b=58.3 Å, c=104.0 Å, beta=119.2°, with space group C2.

2. A three-dimensional structure of c-Abl comprising the atomic structure coordinates of Table 6.

3. A crystal of c-Abl comprising an active conformation of DFG motif.

4. A crystal of claim 3 bound to at least one ligand or low molecular weight compound.

5. A computer readable medium comprising data storage material encoded with computer readable data, wherein said data comprises the atomic coordinates of c-Abl as disclosed in Table 6.

6. A method of determining the three-dimensional structure of c-Abl comprising: (a) crystallization of a polypeptide of c-Abl, the amino acid sequence of which comprises SEQ ID NO. 4 or a mutant, fragment or homologue thereof; and (b) utilizing the atomic coordinates of Table 6 in whole or in part to determine the three-dimensional structure of said polypeptide.

7. A method of determining the three-dimensional structure of a complex comprising a polypeptide of c-Abl, the amino acid sequence of which comprises SEQ ID NO. 4, a mutant, fragment or homologue thereof, bound to at least one ligand comprising: (a) obtaining x-ray diffraction data for crystals of the complex; and (b) utilizing the atomic coordinates of Table 6 in whole or in part to define the three-dimensional structure of the complex.

8. A method of identifying a ligand or low molecular weight compound that binds to c-Abl comprising: (a) utilizing the three-dimensional structure of c-Abl derived in whole or in part from the set of atomic coordinates in Table 6 to identify a potential ligand or low molecular weight compound that binds to c-Abl; and (b) selecting those ligands or low molecular weight compounds that bind to c-Abl.

9. The method of claim 8, wherein the ligand or low molecular weight compound is identified in silico.

10. A method of identifying a ligand or low molecular weight compound that selectively binds to c-Abl comprising: (a) utilizing the three-dimensional structure of c-Abl derived in whole or in part from the set of atomic coordinates in Table 6 to identify a potential ligand or low molecular weight compound that binds selectively to c-Abl; and (b) selecting only those ligands or low molecular weight compounds which bind selectively to c-Abl and to no other tyrosine kinase.

11. The method of claim 10, wherein the ligand or low molecular weight compound is identified in silico.

12. A method of designing a ligand or low molecular weight compound capable of binding to c-Abl comprising: (a) using the atomic coordinates of Table 6 in whole or in part to determine the three dimensional structure of c-Abl; (b) screening said c-Abl with candidate ligands or low molecular weight compounds to determine which bind to c-Abl; (c) selecting those ligands or low molecular weight compounds which bind to c-Abl; and (d) modifying those ligands or low molecular weight compounds which bind to maximize physical properties such as solubility, affinity, specificity or potency.

13. The method of claim 12, wherein the ligand or low molecular weight compound is designed in silico.

14. A method of designing a ligand or low molecular weight compound capable of binding selectively to c-Abl comprising: (a) using the atomic coordinates of Table 6 in whole or in part to determine the three-dimensional structure of c-Abl; (b) screening said c-Abl with candidate ligands or low molecular weight compounds to determine which bind selectively to c-Abl and not to any other tyrosine kinase; (c) selecting those ligands or low molecular weight compounds which bind selectively to c-Abl; and (d) modifying those ligands or low molecular weight compounds which bind to maximize physical properties, such as solubility, affinity, specificity or potency.

15. The method of claim 14, wherein the ligand or low molecular weight compound is identified in silico.