THROUGHPUT SCREENING TO IDENTIFY COCAINE ANTAGONISTS

Information

• Research Project
• 6085793

• ApplicationId

  6085793

• Core Project Number

  R43DA011615

• Full Project Number

  3R43DA011615-01S1

• Serial Number

  11615

• FOA Number

• Sub Project Id

• Project Start Date

  9/30/1997 - 27 years ago

• Project End Date

  3/31/2000 - 24 years ago

• Program Officer Name

  BISWAS, JAMIE

• Budget Start Date

  9/30/1997 - 27 years ago

• Budget End Date

  3/31/2000 - 24 years ago

• Fiscal Year

  1999

• Support Year

  1

• Suffix

  S1

• Award Notice Date

  7/23/1999 - 25 years ago

Organizations

• Guilford Pharmaceuticals Inc.

DESCRIPTION: Although cocaine addiction and overdose represent a significant health problem in the United States, there is currently no available pharmacologic treatment. This Phase I proposal is aimed at testing a large number of compounds using a high throughput screening (HTS) technique to find selective cocaine antagonists or agonist/ antagonists that may be useful in treating cocaine addiction and overdose. Compounds from in vitro binding and uptake studies will be used in in vivo behavior tests to identify potentially useful compounds.

IC Name

• Activity

  R43

• Administering IC

  DA

• Application Type

  3

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  279

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  ZRG2

• Study Section Name

• Organization Name

  GUILFORD PHARMACEUTICALS, INC.

• Organization Department

• Organization DUNS

• Organization City

  BALTIMORE

• Organization State

  MD

• Organization Country

  UNITED STATES

• Organization Zip Code

  21014

• Organization District

  UNITED STATES