Patent Application
20140288495
The present invention relates generally to the field of timed-release capsules administered in beverage preparations.
The following patent applications have been incorporated by reference: US patent 2010/0136183 by Gonus et al., US patent application 2009/0291121 by HAAS et al., US patent application 207/0071808 by Janik et al., US application 2010/0212507 by Hester et al., and US application 2005/0118268 by Percel et al.
The following US patents have been incorporated by reference. U.S. Pat. No. 6,902,751 by Schleifenbaum et al., U.S. Pat. No. 5,958,502 y Fulger et al., U.S. Pat. No. 5,709,895 by Tanaka et al. U.S. Pat. No. 5,601,865 by Fulger et al., U.S. Pat. No. 5,399,368 by Garwood et al., U.S. Pat. No. 4,232,047 by Sair et al., U.S. Pat. No. 3,431,339 by Gyarmathy et al., U.S. Pat. No. 2,004,957 by Messner, U.S. Pat. No. 5,021,249 by Bunick et al., U.S. Pat. No. 4,689,235 by Barnes et al., U.S. Pat. No. 6,204,243 by Posanski, U.S. Pat. No. 5,401,512 by Rhodes et al., U.S. Pat. No. 6,663,888 by Percel et al., U.S. Pat. No. 6,500,454 by Percel et al., and U.S. Pat. No. 7,048,945 by Percel et al.
The preparation of a beverage with ingredients that retain their flavor over a long period of time or retain a relatively mixed or homogeneous composition through the drinking process can be complicated. Additionally, while it may be desirable to orally administer pharmaceutical compounds, vitamins, or other active compounds, including herbal ingredients, in a liquid beverage, the variety of ingredients found in these beverages and the potential effect they may have on the compound being administered has prevented their use for this purpose. This is further complicated by the fact that many beverages contain a variety of ingredients with different densities that may be hydrophobic or hydrophilic substances, further adding to the difficulty of maintaining a near homogeneous mix of beverage ingredients over a period of time.
For instance, the blending of a mixed drink such as coffee or tea requires the preparer to mix together a variety of different ingredients. There is a large number of coffee recipes, each requiring different ingredients, such as for example caffè Americano, café au lait, café Bombóm, café mélange, cafe mocha, Ca phe sua da, café cortado, eiskaffee, espresso Romano, flat white, Indian filter coffee, Kopi susu, caffè macchiato mazagran, mochasippi, Turkish coffee, Vienna coffee, yuanyang, etc.
Furthermore, there are a number of coffees based on liquors including but not limited to Irish coffee (Whiskey), Brandy coffee (Brandy), keoke coffee (Brandy and Kahl a), English coffee (Gin), calypso coffee (Tia Maria or Kahl a and Rum), Jamaican coffee (Tia Maria & Rum), shin shin coffee (Rum), Baileys Irish cream coffee, monk's coffee (Benedictine), Seville coffee (Cointreau), witch's coffee (Strega), Russian coffee (Vodka), priest coffee (Brennivin), Corfu coffee (Koum Quat liquor), kaffee fertig (coffee with Swiss prune schnapps), caffe corretto. Coffee is sold and used in mixed drinks in the form of beans, ground beans, or in instant-mix powders.
There are a large number of tea recipes including but not limited to white tea, yellow tea, green tea, oolong tea, black tea, pu'er tea, and a much larger number of herbal teas. Tea and coffee additives can include sweeteners such as honey, and flavors such as mint. Tea comes in leaves, in bags or in powder.
Many other beverages exist beside mixed drinks that include coffees and teas, which require their own ingredients and are sold in their own unique packages. These include but are not limited to beer, wine, sangria, cider, hot cider, hot chocolate, holicks, etc.
Sometimes the preparation of a multi-ingredient beverage requires that a base liquid be added such as for example water, milk, soda water, wine, cider, beer, ethyl alcohol, or fruit juice.
The large range of ingredients used in beverage preparation presents a problem should the beverage also contain ingredients designed for long-term flavor delivery, color maintenance, vitamin augmentation, or delivery of pharmaceutical or herbal compounds.
In addition to the complexity of beverage preparation, is the problem of loss of taste through the phenomenon of habituation, which manifests when a sense is exposed to a stimulus for a period of time and thereby it loses its sensitivity to that stimulus. More particularly, a drink's flavor that may appear to be intense initially loses some of its intensity after the taste buds become used to that flavor. The prior art does not adequately address this problem.
Additionally, many vitamins, pharmaceutical compounds, or other active compounds including herbal ingredients might be added to a beverage for the purpose of providing ingredients that should be processed in the stomach during digestion or otherwise broken down and absorbed through the intestine in order to become efficacious. However, the prior art does not provide a method for effective delivery of these ingredients, using an oral delivery method involving a liquid beverage, in a manner that protects the relevant ingredient so that it is processed and absorbed to maximize exposure to and effectiveness of a delivered compound.
Furthermore, there are certain combinations of pharmaceutical compounds, vitamins, and other active compounds, known to have a synergistic effect, where the use of one compound influences the efficacy of another. An example of this is the relationship between codeine and paracetamol. The combination of the aforementioned compounds is known to have an increased analgesic effect. In addition, certain pharmaceutical compounds have known side effects, which may be minimized if absorbed before or after another compound known to treat those particular side effects. For example, antibiotics such as penicillin and amoxicillin are known to cause diarrhea, nausea, vomiting, and stomach pain. Nausea, for example, can be treated with bismuth subsalicylate. If bismuth subsalicylate is digested prior to the metabolism of an antibiotic, there may be a reduction in the side effects experienced by the consumer. Prior art does not address the simultaneous consumption of compounds to alleviate side effects or increase efficacy by using an oral delivery method involving a liquid beverage.
In addition, many consumers are required to take multiple medications daily, and sometimes in a particular order. There is no prior art available addressing the use of an oral delivery method involving a liquid beverage to take multiple, different compounds per day in a particular order.
It is therefore one object of this invention to simplify the task of complex drink preparation. It is another object of the invention to mitigate the phenomenon of habituation and sustain a drink's taste intensity. Additionally, the invention provides for delayed-release drink color enhancement. The invention may also be used for the oral administration of pharmaceutical compounds, vitamins, or other active compounds including herbal ingredients to a person or veterinary patient in a liquid beverage.
Further features, aspects, and advantages of the present invention over the prior art will be more fully understood when considered in light of the following detailed description and claims.
As such, considering the foregoing, it may be appreciated that there continues to be a need for novel and improved devices and methods for delivering flavors and medications.
The foregoing needs are met, to a great extent, by the present invention; wherein in aspects of this invention, enhancements are provided to the existing models of administering of flavors and medication to beverages, in the form of various embodiments of specially designed capsules and related devices.
The phenomenon of habituation is well known and well documented. It refers to a type of non-associative learning in which repeated exposure to a stimulus leads to decreased response to it. This phenomenon is responsible for after-images seen in the eyes after the retina has been exposed to an image. The same phenomenon applies to other senses, in particular, the sense of taste. Related to this, the second sip of a drink is usually less “tasty” or stimulating to the taste buds than the first. In an aspect, this invention mitigates the habituation phenomenon and sustains the intensity of a drink tasting experience by varying or modulating the taste of a beverage, over time. It utilizes time-release technologies involving capsules to expose the taste buds to flavors in a drink over an extended period, thereby exciting the sense of taste over a longer period of time.
Aspects of the present invention may be used for administration of delayed-release flavor or color enhancement of beverage preparations. It may also be used for the oral administration of pharmaceutical compounds, vitamins, or other active compounds, including herbal ingredients, to a person or animal in a liquid beverage.
In addition, aspects of this invention provide an added practical benefit in that it streamlines the task of the beverage preparer by combining, into a single capsule, a number of beverage ingredients that may be deposited into the liquid base for faster and easier preparation of mixed drinks.
In one aspect, the invention comprises a capsule filled with a matrix that contains (sequestered inside) the primary flavor, which suffuses through the beverage after the matrix has dispersed or dissolved in the beverage. Included inside this matrix are additional flavors captured in inner bodies that are designed to dissolve at later time intervals after they are released from the matrix. These inner bodies contain secondary, tertiary, and additional flavors that release after the primary beverage flavor response of the taste buds has subsided. In another beneficial aspect of the invention, a large number of inner bodies sequestered in a capsule produce a more complex flavor-time profile for the person drinking the beverage.
In this aspect, the invention comprises a capsule for delayed release of one or more flavor ingredients in a beverage, the timed releases occurring in multiple stages due to the gradual degradation or dissolution of the capsule constituents, which results in a delayed release of flavor trapped within the capsule. The capsule comprises:
The shell, matrix, and inner bodies may optionally contain additional ingredients that are released into the beverage in corresponding stages. The invention includes embodiments wherein a variety of different types of inner bodies are assembled in coating layers, each layer having a predetermined rate of dissolution that is designed to achieve the desired time-release profile for the capsule's constituent ingredients. These additional inner bodies may include color enhancers that, when released into the beverage, change the hue of the beverage over time.
In another aspect, a composite timed release capsule can include:
In yet another aspect, a composite straw can include:
In various aspects, the invention can also include capsule embodiments designed for oral administration of pharmaceutical compounds, vitamins, or other active compounds including herbal ingredients to a person or veterinary patient in a liquid beverage, according to a predetermined time profile. These compounds may be placed in inner bodies that are inserted, embedded, or floating in the matrix. Because the ingredients of these inner bodies are exposed to liquid and processed at a later time period, this timed release profile is advantageous for the delivery of compounds that should be processed in the stomach or digestive track to be efficacious. In addition, the order of which the compounds dissolve can be advantageous to increase the efficacy of the compound or compounds, or limit the potential harmful side effects of the previous or subsequent compounds. The invention could also be used to administer compounds to patients who take multiple pharmaceuticals per day and in a particular order.
There has thus been outlined, rather broadly, certain embodiments of the invention in order that the detailed description thereof herein may be better understood, and in order that the present contribution to the art may be better appreciated. There are, of course, additional embodiments of the invention that will be described below and which will form the subject matter of the claims appended hereto.
In this respect, before explaining at least one embodiment of the invention in detail, it is to be understood that the invention is not limited in its application to the details of construction and to the arrangements of the components set forth in the following description or illustrated in the drawings. The invention is capable of embodiments in addition to those described and of being practiced and carried out in various ways. In addition, it is to be understood that the phraseology and terminology employed herein, as well as the abstract, are for the purpose of description and should not be regarded as limiting.
As such, those skilled in the art will appreciate that the conception upon which this disclosure is based may readily be utilized as a basis for the designing of other structures, methods and systems for carrying out the several purposes of the present invention. It is important, therefore, that the claims be regarded as including such equivalent constructions insofar as they do not depart from the spirit and scope of the present invention.
Before describing the invention in detail, it should be observed that the present invention resides primarily in a novel and non-obvious combination of elements and process steps. So as not to obscure the disclosure with details that will readily be apparent to those skilled in the art, certain conventional elements and steps have been presented with lesser detail, while the drawings and specification describe in greater detail other elements and steps pertinent to understanding the invention.
The following embodiments are not intended to define limits as to the structure or method of the invention, but only to provide exemplary constructions. The embodiments are permissive rather than mandatory and illustrative rather than exhaustive.
In the following, we describe the structure of an embodiment of a timed release capsule 100 with reference to
An embodiment of the present invention comprises a capsule that contains the ingredients required to prepare a blended beverage that includes at least one time-release component. When the capsule is dissolved in liquid, such as for example water, milk, alcohol or juice, flavors, colors, compounds and other constituents of the capsule can be released at various time intervals.
In an embodiment, illustrated in
In various related embodiments, the water-soluble capsule shell 102 can be made of a material that dissolves easily in water. Materials suitable for use as a time-release capsule shell are well known in the art, and can for example include hydroxyethyl cellulose.
In various related embodiments, the thickness of the capsule shell 102 can depend on its desired usefulness in a beverage delivery system and on how quickly the capsule is designed to dissolve in liquid preparations. The outside diameter of a timed release capsule 100 can typically be in a range of 1.5-3.5 inches and thickness of the capsule shell 102 can typically range from 1/16 to ⅛ of an inch. In some embodiments, outside diameter and shell thickness can, depending on application, fall outside these typical ranges.
In an embodiment, the composition of the capsule shell 102 can be selected to be soluble in liquid when a predetermined condition is met, such as certain time duration, a predetermined temperature, or a certain amount of agitation of the liquid. An inner body 110120130140 typically ranges from ⅛ to ¾ of an inch in its outer diameter. These inner bodies are designed to fit well within a capsule and its constituent matrix. Optionally, these inner bodies are coated with a material that dissolves when exposed to liquid, such as hydroxyethyl cellulose.
For example, if a hot beverage is prepared, the capsule wall 102 can optionally begin to dissolve around 88° F. Alternatively, the capsule wall 102 may be designed to break open when the liquid it is contained within is vigorously shaken. In yet another embodiment of the present invention, the capsule wall can be relatively thick and only start to dissolve significantly after being exposed to liquid for at least 5 minutes.
The matrix 104 of
The matrix 104 of
In a related embodiment,
The capsule of
Additionally, the timed release capsule 100 may also be used to deliver and release pharmaceutical compounds, vitamins, or other active compounds, including herbal ingredients, to a person or animal through oral administration in a beverage, over time. Thus, a beverage may be prepared that releases compounds in the inner bodies during digestion in the stomach or in the intestine, after the capsule and matrix degrade and release the inner bodies. The present invention may be used for the oral administration of compounds to a person or animal in a liquid beverage.
In an example embodiment, a timed release capsule 100 can be designed to deliver a flavored coffee beverage by dissolving it in hot water, wherein the timed release capsule 100 further comprises:
In another example embodiment, a timed release capsule 100 can be designed to deliver a mango-flavored water, with high vitamin content, in an energy drink by dissolving the capsule in cold water, wherein the timed release capsule 100 further comprises:
In yet another example embodiment, a timed release capsule 100 can be designed to deliver an alcoholic beverage containing vitamins and flavors, by dissolving it in an alcoholic liquid, such as vodka, wherein the timed release capsule 100 further comprises:
a) A capsule shell 102, composed of the following ingredients by weight:
b) A matrix 104, comprising by weight:
In various related embodiments, even though the above narrative describes the timed release of flavors found in inner bodies in a drink, the same approach may also be used to deliver a timed release of nutrients, such as vitamins or herbs, compounds, or visual effects, such as colors. In one aspect of the invention, a change in color may be synchronized with the change in flavor to indicate, for example, the point of maximum flavor intensity for a particular flavor. These changes are driven by release of the inner bodies from the capsule matrix and degradation of any additional protective coating located directly around the inner bodies, which allows their ingredients to mix with the beverage.
In another embodiment of the present invention, the capsule contents, including at least some of the inner bodies, can provide a person or veterinary patient with an oral dosage or administration of pharmaceutical compounds, vitamins, other active compounds, or herbal ingredients in a liquid beverage.
In another embodiment, as shown in
In a related embodiment, the capsule can incorporate pharmaceutical compounds, vitamins, herbal remedies, or other compounds used for a medical treatment. The thickness of the coating 312 and the layers 302304306308310 contribute to the ability to delay release of the compounds sequestered in the inner layers. The capsule size, coating and matrix thickness, and other properties can be adjusted to achieve delayed release profiles appropriate for oral delivery of compounds to children, adults, or veterinary patients, based on their digestive systems and digestive profiles. Such compounds delivered via oral administration in a capsule placed in a liquid beverage can include cold medicine such as Robitussin, digestive aids, such as Pepto-Bismol, or any other compound that is appropriate for oral ingestion and remains active when administered via the digestive system.
In yet another embodiment, a timed release capsule 100 can be specially formulated for veterinary patients. For example, when the patient is a cat, the capsule may include taurine or catnip to promote ingestion of the formulation.
In an additional embodiment, the timed release capsule 100 may be used to deliver three separate doses of pharmaceutical compounds, vitamins, other active compounds, or any combination of the aforementioned compounds. This embodiment could be used to deliver compounds in stages to minimalize potential side effects, increase the efficacy of the compounds or subsequent compounds, ensure the consumption of medication, or ensure the correct dosage of medication in the correct order.
In an example of minimizing potential side effects, amoxicillin can be used for the treatment of bacterial infections and is known to cause potential side effects like diarrhea, vomiting, or nausea. In contrast, bismuth subsalicylate can be used to treat diarrhea, heartburn, nausea, and upset stomach. In addition, vomiting and diarrhea can cause dehydration and electrolyte imbalance, which an aqueous solution of vitamins and electrolytes could replenish. Thus, the timed release capsule 100 may comprise of a matrix 104 of flavor, which dissolves in an aqueous solution; an inner body 110 of vitamins and electrolytes, delivered when a first condition is met; an inner body 120 containing bismuth subsalicylate as the inner material 124, delivered when a second condition is met generally after the first dose; and an inner body 130 containing a liquid dosage of amoxicillin as the liquid 134, which is delivered when a third condition is met and generally after the first and second dose is delivered.
In an example of increasing the efficacy of a compound, published reports have shown that certain drugs have a low absorption at high gastric pH levels. In a related embodiment, the timed release capsule 100 may comprise of a matrix 104 of a certain flavor, which dissolves in an aqueous solution when a first condition is met; an inner body 120 comprised of a compound 124 to lower the gastric pH levels, which dissolves when a second certain condition is met; and an inner body 130 containing a compound that absorbs affectively at lower gastric pH levels, which is delivered when a third condition is met.
In an embodiment, as illustrated in
In a related embodiment, a composite timed release capsule 400, can comprise:
In a further related example embodiment, the composite timed release capsule 400, can be structured, such that:
In a further related embodiment, the outer coating 144 can be any of a plurality of well-known coatings and pharmaceutical films, which will resist dissolution in water, but will dissolve rapidly in an acidic environment, such as the stomach of a human or a pet. Similarly, the inner coating 143 can be selected from well-known enteric coatings, such as for example a pharmaceutical glaze.
In various further related embodiments, the inner bodies 110120130140 can have various densities, such that the inner bodies 110120130140 can either become suspended or floating in an aqueous liquid, or can sink or float.
In a related embodiment, a change in color can let a user know that a drink is ready. In a further related embodiment, dissolution of the third material can cause a color shift of the drink, which can indicate that the drink is ready.
In a related embodiment, a beverage can undergo two or more color shifts during dissolution of a timed release capsule 400.
In a related embodiment, a beverage can become effervescent during the dissolution of a timed release capsule 100 or a composite timed release capsule 400. In a further related embodiment, a timed release capsule 100 can be configured such that the matrix 104 contains an effervescent agent, or a composite timed release capsule can be configured such that the third material contains an effervescent agent. The effervescent agent can for example be a mixture of citric acid and sodium bicarbonate. In a related embodiment, the matrix 104 can be pressure formed, such that no further coating 102 is necessary.
In a related embodiment, a timed release capsule 400 can be so designed as to permit use for more than one personal beverage, similar to reuse of a tea bag for brewing of more than one cup of tea.
In various related embodiment, a timed release capsule 400 can be configured in a plurality of different sizes. For example, a larger size a timed release capsule 400 can be configured for use with more than one personal beverage.
In various related embodiments, a timed release capsule 400 can further comprise:
In various further related embodiments, any layer 402404406 or inner bodies 110120130140 of the timed release capsule 400 may comprise prebiotic and/or probiotic materials. In a yet further related embodiment, a timed release capsule 400 comprising both prebiotic and probiotic materials may provide a symbiotic function in the digestive system.
In a related embodiment, as shown in
In various other embodiments, the composite timed release capsule 400 can be configured with a variety of diameters, to fit inside a variety of standard straws 504, which can include thin, medium, standard, or oversize straws.
In an embodiment, a composite straw 600, as illustrated in
In an embodiment, a composite straw 700, as illustrated in
In various embodiments, the timed release capsules 100 and/or composite timed release capsules 400 can be packaged with beverages or beverage containers such that the timed release capsules 400 can be released into the beverage before consumption.
In a related embodiment, the inner bodies 120140 can have a density greater than 1 gram/cm3, such that the released inner bodies can fall through the lower stop into the beverage.
In a related embodiment, the inner bodies 120140 can have a density substantially similar to 1 gram/cm3, such that the released inner bodies can become suspended in the beverage inside the straw, and the user can subsequently ingest the inner bodies directly from the composite straw 600700.
In a related embodiment, the wall of the straw 504, can further include perforations 606, to allow for passage of dissolved parts of the timed release capsules 400 to pass into the full volume of the beverage.
In a related embodiment, the wall of the straw 504, can further include perforations 606, to allow for passage of dissolved parts of the timed release capsules 400 to pass into the full volume of the beverage.
In an embodiment, a composite straw 600 or a composite straw 700 can include a first composite timed release capsule 400, which is designed to control the flow of a beverage, for example to prevent flow of a hot beverage, such as near boiling coffee or tea. In a related embodiment, the first composite timed release capsule 400 can include a coating which has retrograde or inverse temperature dependent solubility, such that the coating is almost insoluble above a pre-determined temperature, which typically can be in a range from 68 degrees Celsius to 100 degrees Celsius. In a further related embodiment, the first material of the first composite timed release capsule 400 can have retrograde or inverse temperature dependent solubility. In a further related embodiment, the first composite timed release capsule 400, can be positioned above other timed release capsules 400, and above any perforations 606 of the straw 504 wall.
In a related example, illustrated in
One advantage of various embodiments of this invention is that they can resolve the problem of incompatible formulas, in which formula components would not be stable or form homogeneous solutions if mixed together at manufacturing time, and therefore give the manufacturer a wide range of new options concerning the various components that may be used. In other words, a capsule can be manufactured at one time and consumed at another time. Its components such as the shell, the matrix, or any one of the inner bodies could comprise chemicals or other compounds that lose some or all of their activity if they were combined or come in contact with each other during the manufacturing process. The solution provided by this invention involves the mixing of these constituents at the time of dissolution in a beverage, thereby avoiding or reducing concerns regarding loss of activity.
The many features and advantages of the invention are apparent from the detailed specification, and thus, it is intended by the appended claims to cover all such features and advantages of the invention, which fall within the true spirit and scope of the invention.
Many such alternative configurations are readily apparent, and should be considered fully included in this specification and the claims appended hereto. Accordingly, since numerous modifications and variations will readily occur to those skilled in the art, it is not desired to limit the invention to the exact construction and operation illustrated and described, and thus, all suitable modifications and equivalents may be resorted to, falling within the scope of the invention.
This application is a continuation-in-part of U.S. application Ser. No. 13/570,066, filed Aug. 8, 2012, which is the non-provisional application for U.S. Provisional Application No. 61/521,978 filed Aug. 10, 2011.
| Number | Date | Country | |
|---|---|---|---|
| 61521978 | Aug 2011 | US |
| Number | Date | Country | |
|---|---|---|---|
| Parent | 13570066 | Aug 2012 | US |
| Child | 14296392 | US |
