TREA

Tissue rejection

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Information

  • Patent Grant
  • 7666596
  • Patent Number
    7,666,596
  • Date Filed
    Monday, May 15, 2006
    18 years ago
  • Date Issued
    Tuesday, February 23, 2010
    14 years ago
Information
Abstract
This document relates to methods and materials involved in detecting tissue rejection (e.g., organ rejection). For example, this document relates to methods and materials involved in the early detection of kidney tissue rejection.
Description
TECHNICAL FIELD

This document relates to methods and materials involved in tissue rejection (e.g., organ rejection) and detecting tissue rejection.


BACKGROUND

The transplantation of tissue from one mammal to another has been used for years to save lives and to improve the quality of lives. For example, the first successful kidney transplant was performed in the mid-1950s between identical twin brothers. Since then, donors have grown to include not only close relatives but also distant relatives, friends, and total strangers. In some cases, the recipient may reject the transplanted tissue. Thus, tissue rejection is a concern for any recipient of transplanted tissue. If a doctor is able to recognize early signs of tissue rejection, anti-rejection medication often can be used to reverse tissue rejection.


SUMMARY

This document relates to methods and materials involved in detecting tissue rejection (e.g., organ rejection). More particularly, this document relates to methods and materials involved in the early detection of tissue rejection (e.g., kidney rejection) and the assessment of a mammal's probability of rejecting tissue such as a transplanted organ. For example, this document provides nucleic acid arrays that can be used to diagnose tissue rejection in a mammal. Such arrays can allow clinicians to diagnose tissue rejection early based on a determination of the expression levels of nucleic acids that are differentially expressed in tissue being rejected as compared to control tissue not being rejected. The differential expression of such nucleic acids can be detected in tissue being rejected prior to the emergence of visually-observable, histological signs of tissue rejection. Early diagnosis of patients rejecting transplanted tissue (e.g., a kidney) can help clinicians determine appropriate treatments for those patients. For example, a clinician who diagnoses a patient as rejecting transplanted tissue can treat that patient with medication that suppresses tissue rejection (e.g., immunosuppressants).


The description provided herein is based, in part, on the discovery of nucleic acids that are differentially expressed in tissue being rejected as compared to control tissue that is not being rejected. Such nucleic acids can be nucleic acids that are induced by, for example, gamma interferon (IFN-γ). The term “gamma interferon induced transcripts” or “GITs” as used herein refers to transcripts that are expressed in kidneys of mammals treated with IFN-γ at a level at least 2-fold greater than the level of expression in normal kidney tissue. In some embodiments, a “GIT” is identified based expression that is increased at least two-fold in response to IFN-γ in normal kidneys of one or more particular strains (e.g., B6, CBA, and/or BALB/c) as compared to the level of expression in untreated normal kidney. The term “rejection induced transcripts” or “RITs” as used herein refers to transcripts that are elevated at least 2-fold in WT kidney allografts at day 5 post transplant in WT hosts vs. normal kidneys. In some embodiments, a “RIT” is identified based on expression that is increased at least two-fold in WT allografts from one or more particular strains (e.g., B6, CBA, and/or BALB/c) as compared to the level of expression in normal kidney. The term “injury and repair-induced transcripts” or “IRITs” refers to transcripts that are increased at least two-fold in isografts at least once between day 1 and day 21, as compared to normal kidney, and also are increased at least two-fold in CBA allografts at day 5 as compared to normal kidneys.


The term “gamma interferon and rejection induced transcripts” or “GRITs” as used herein refers to IFN-γ and rejection-inducible transcripts. These transcripts are (a) expressed at a level at least 2-fold greater in kidney tissue of mammals treated with IFN-γ than in kidney tissue of untreated mammals, (b) elevated at least 2-fold in tissue from WT kidney allografts at day 5 post transplant in WT hosts as compared to normal kidney tissue, and (c) expressed at levels at least 2-fold lower in kidney tissue from IFN-γ-deficient (GKO) D5 allografts as compared to WT D5 allografts. Thus, the expression of GRITs is affected by the presence or absence of IFN-γ in allografts. The term “GRIT-like” transcripts as used herein refers to transcripts that are (a) expressed at a level at least 2-fold greater in kidney tissue of mammals treated with IFN-γ than in kidney tissue of untreated mammals, (b) elevated at least 2-fold in tissue from WT kidney allografts at day 5 post transplant in WT hosts as compared to normal kidney tissue, and (c) not lower or even increased when IFN-γ is absent in GKO D5 allografts compared to WT D5 allografts. GRIT-like transcripts, despite being inducible by rIFN-γ, are increased in allografts by mechanisms largely independent of IFN-γ.


The term “transcript” as used herein refers to an mRNA identified by one or more numbered Affymetrix probe sets, while a “unique transcript” is an mRNA identified by only one probe set. The term “true interferon gamma dependent and rejection-induced transcripts” or “tGRITs” refers to rejection-induced transcripts that are IFN-γ-dependent in rejection, and also are unique transcripts that are increased at least 2-fold by rIFN-γ. The term “occult interferon gamma dependent and rejection-induced transcripts” or “oGRITs” refers to GRITs that are unique transcripts, but that are not 2-fold induced by rIFN-γ in normal kidneys.


The description provided herein also is based, in part, on the discovery that the expression levels of RITs can be used to distinguish transplanted tissue that is being rejected from transplanted tissue that is not being rejected. For example, the expression levels of nucleic acids listed in Table 2, Table 7, and/or Table 11 can be assessed in transplanted tissue to determine whether or not that transplanted tissue is being rejected. In addition, the description provided herein is based, in part, on the discovery that the expression levels of RITs (e.g., those listed in Table 2, Table 7, and/or Table 11) can be used to distinguish transplanted tissue that is being rejected from transplanted tissue that is not being rejected at a time point prior to the emergence of any visually-observable, histological sign of tissue rejection (e.g., tubulitis for kidney rejection). In some embodiments, expression levels of GRITs or GRIT-like transcripts, including, for example, those listed in Tables 4, 5, and 9 can be assessed to determine whether or not transplanted tissue is being rejected or to distinguish transplanted tissue that is being rejected from transplanted tissue that is not being rejected.


In one aspect, this document features a method for detecting tissue rejection. The method can include determining whether or not tissue transplanted into a mammal contains cells that express at least two of the nucleic acids listed in Table 2 or Table 11 at elevated levels, wherein the presence of the cells indicates that the tissue is being rejected. The mammal can be a human. The tissue can be kidney tissue or a kidney. The method can include determining whether or not the tissue contains cells that express at least five of the nucleic acids, at least ten of the nucleic acids, or at least twenty of the nucleic acids. The determining step can include measuring the level of mRNA expressed from the at least two nucleic acids or measuring the level of polypeptide expressed from the at least two nucleic acids. The method can include determining whether or not the tissue contains cells that express at least two of the nucleic acids at a level greater than the average level of expression exhibited in cells from control tissue that has not been transplanted.


In another aspect, this document features a method for detecting tissue rejection. The method can include determining whether or not a sample contains cells that express at least two of the nucleic acids listed in Table 2 or Table 11 at elevated levels, wherein the sample contains cells, was obtained from tissue that was transplanted into a mammal, and was obtained from the tissue within fifteen days of the tissue being transplanted into the mammal, and wherein the presence of the cells indicates that the tissue is being rejected. The mammal can be a human. The tissue can be kidney tissue or a kidney. The method can include determining whether or not the sample contains cells that express at least five of the nucleic acids, at least ten of the nucleic acids, or at least twenty of the nucleic acids. The determining step can include measuring the level of mRNA expressed from the at least two nucleic acids or measuring the level of polypeptide expressed from the at least two nucleic acids. The sample can be obtained from the tissue within ten days of the tissue being transplanted into the mammal or within five days of the tissue being transplanted into the mammal. The method can include determining whether or not the sample contains cells that express at least two of the nucleic acids at a level greater than the average level of expression exhibited in cells from control tissue that has not been transplanted.


In another aspect, this document features a nucleic acid array containing at least 20 nucleic acid molecules, wherein each of the at least 20 nucleic acid molecules has a different nucleic acid sequence, and wherein at least 50 percent of the nucleic acid molecules of the array contain a sequence from nucleic acid selected from the group consisting of the nucleic acids listed in Table 2 and Table 11. The array can contain at least 50 nucleic acid molecules, wherein each of the at least 50 nucleic acid molecules has a different nucleic acid sequence. The array can contain at least 100 nucleic acid molecules, wherein each of the at least 100 nucleic acid molecules has a different nucleic acid sequence. Each of the nucleic acid molecules that contain a sequence from a nucleic acid selected from the group can contain no more than three mismatches. At least 75 percent of the nucleic acid molecules of the array can contain a sequence from nucleic acid selected from the group. At least 95 percent of the nucleic acid molecules of the array can contain a sequence from nucleic acid selected from the group. The array can include glass. The at least 20 nucleic acid molecules can contain a sequence present in a human.


In another aspect, this document features a computer-readable storage medium having instructions stored thereon for causing a programmable processor to determine whether one or more nucleic acids listed in Table 2 or Table 11 are detected in a sample, wherein the sample is from a transplanted tissue. The computer-readable storage medium can further have instructions stored thereon for causing a programmable processor to determine whether one or more of the nucleic acids listed in Table 2 or Table 11 is expressed at a greater level in the sample than in a control sample of non-transplanted tissue.


This document also features an apparatus for determining whether a transplanted tissue is being rejected. The apparatus can include one or more collectors for obtaining signals representative of the presence of one or more nucleic acids listed in Table 2 or Table 11 in a sample from the transplanted tissue, and a processor for analyzing the signals and determining whether the tissue is being rejected. The one or more collectors can be configured to obtain further signals representative of the presence of the one or more nucleic acids in a control sample from non-transplanted tissue.


Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention, suitable methods and materials are described below. All publications, patent applications, patents, and other references mentioned herein are incorporated by reference in their entirety. In case of conflict, the present specification, including definitions, will control. In addition, the materials, methods, and examples are illustrative only and not intended to be limiting.


The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the invention will be apparent from the description and drawings, and from the claims.





DESCRIPTION OF DRAWINGS


FIG. 1 is a depiction of selection criteria used for identification of GRITs and GRIT-like transcripts. WT D5—wild type allografts, GKO D5—IFN-γ-deficient allografts.



FIG. 2A is a depiction of an unsupervised hierarchical clustering of GRITs. FIG. 2B is a graph showing an expression time course of GRITs in injury and rejection. FIG. 2C is a graph showing the signal strength of IFN-γ over the time course of in injury and rejection. Clustering was based on distance as the similarity measure. ISO—isografts, WT—allografts, NCBA—control kidneys.



FIG. 3A is a depiction of an unsupervised hierarchical clustering of GRIT-like transcripts. FIG. 3B is a graph showing an expression time course of GRIT-like transcripts in injury and rejection. Normalized values are shown. Clustering was based on distance as the similarity measure. ISO—isografts, WT—allografts, NCBA—control kidneys.



FIGS. 4A, 4B, and 4C are graphs showing expression profiles of IFN-γ, GRITs, and GRIT-like transcripts, respectively, early after transplantation. ISO—isografts, WT—allografts, GKO D5—IFN-γ deficient grafts, NCBA—control kidneys.



FIG. 5A is a depiction of an unsupervised hierarchical clustering of injury-induced RIT. FIG. 5B is a graph showing an expression time course of RIT in injury and rejection. Normalized values are shown. Clustering was based on distance as the similarity measure. ISO—isografts, WT—allografts, NCBA—control kidneys.



FIG. 6A is a graph showing expression profiles of acute phase markers in isografts and allografts. FIG. 6B is a graph showing the expression profiles of Tgfbi and the average expression profile of injury-induced RIT in isografts and allografts. Normalized values are shown in both graphs. ISO—isografts, WT—allografts, NCBA—control kidneys.



FIG. 7A is a graph showing an expression profile of Tgfbi superimposed on that for injury-induced RIT. FIG. 7B is a graph showing an expression profile of STAT-1 superimposed on that for injury-induced RIT.



FIG. 8A is a diagram of an algorithm for identifying GRITs. FIG. 8B is a diagram of an algorithm for identifying RITs. FIG. 8C is a diagram of an algorithm for identifying tGRITs and oGRITs.



FIG. 9 is a diagram of an algorithm for identifying IRITs.





DETAILED DESCRIPTION

This description provides methods and materials involved in detecting tissue rejection (e.g., organ rejection). For example, this description provides methods and materials that can be used to diagnose a mammal (e.g., a human) as having transplanted tissue that is being rejected. A mammal can be diagnosed as having transplanted tissue that is being rejected if it is determined that the tissue contains cells that express elevated levels of one or more RITs or that express elevated levels one or more of the nucleic acids listed in Table 2, Table 7, or Table 11. In some embodiments, a mammal can be diagnosed as having transplanted tissue that is being rejected if it is determined that the tissue contains cells that express elevated levels of one or more GRITs, GRIT-like, true GRIT, or occult GRIT transcripts including, without limitation, those listed in Tables 4, 5, 9, or 10, respectively.


The methods and materials provided herein can be used to detect tissue rejection in any mammal such as a human, monkey, horse, dog, cat, cow, pig, mouse, or rat. In addition, the methods and materials provided herein can be used to detect rejection of any type of transplanted tissue including, without limitation, kidney, heart, liver, pancreas, and lung tissue. For example, the methods and materials provided herein can be used to determine whether or not a human who received a kidney transplant is rejecting that transplanted kidney.


Any type of sample containing cells can be used to determine whether or not transplanted tissue contains cells that express one or more RITs or that express one or more of the nucleic acids listed in Table 2, Table 7, or Table 11 at elevated levels. Similarly, any type of sample containing cells can be used to determine whether or not transplanted tissue contains cells that express one or more GRITs, GRIT-like, true GRIT, or occult GRIT transcripts, or that express one or more of the nucleic acids listed in Table 4, Table 5, Table 9, or Table 10 at elevated levels. For example, biopsy (e.g., punch biopsy, aspiration biopsy, excision biopsy, needle biopsy, or shave biopsy), tissue section, lymph fluid, blood, and synovial fluid samples can be used. In some embodiments, a tissue biopsy sample can be obtained directly from the transplanted tissue. In some embodiments, a lymph fluid sample can be obtained from one or more lymph vessels that drain from the transplanted tissue. A sample can contain any type of cell including, without limitation, cytotoxic T lymphocytes, CD4+ T cells, B cells, peripheral blood mononuclear cells, macrophages, kidney cells, lymph node cells, or endothelial cells.


As explained herein, a RIT refers to a transcript that is elevated at least 2-fold in WT kidney allografts at day 5 post transplant in WT hosts vs. normal kidneys. Examples of RITs include, without limitation, those listed in Tables 2, 7, and 11. A GRIT refers to an IFN-γ and rejection induced transcript that is (a) expressed at a level at least 2-fold greater in kidney tissue of mammals treated with IFN-γ than in kidney tissue of untreated mammals, (b) elevated at least 2-fold in tissue from WT kidney allografts at day 5 post transplant in WT hosts as compared to normal kidney tissue, and (c) expressed at levels at least 2-fold lower in kidney tissue from IFN-γ-deficient (GKO) D5 allografts as compared to WT D5 allografts. Examples of GRITs include, without limitation, the nucleic acids listed in Table 4. A GRIT-like transcript refers to a transcript that is (a) expressed at a level at least 2-fold greater in kidney tissue of mammals treated with IFN-γ than in kidney tissue of untreated mammals, (b) elevated at least 2-fold in tissue from WT kidney allografts at day 5 post transplant in WT hosts as compared to normal kidney tissue, and (c) not lower or even increased when IFN-γ is absent in GKO D5 allografts compared to WT D5 allografts. Examples of GRIT-like transcripts include, without limitation, those listed in Table 5. Additional examples of RITs, GRITs, and GRIT-like transcripts can be identified using the procedures described herein. For example, the procedures described in Example 1 can be used to identify RITs, GRITs, and GRIT-like transcripts other than those listed in Tables 2, 4, 5, and 7.


A tGRIT refers to a unique transcript that is rejection-induced and IFN-γ-dependent in rejection, and also is increased at least two-fold by rIFN-γ. Examples of tGRITs include, without limitation, those listed in Table 9. An oGRIT refers to a GRIT that is a unique transcript, but that is not induced at least 2-fold by rIFN-γ in normal kidneys. Examples of oGRITs include, without limitation, those listed in Table 10. An IRIT refers to a transcript that is increased at least two-fold in isografts at least once between day 1 and day 21, as compared to normal kidney, and also increased at least two-fold in CBA allografts at day 5 as compared to normal kidneys. Examples of IRITs include, without limitation, those listed in Table 11. The procedures described in Example 2 can be used to identify RITs, IRITs, GRITs, true GRITs, and occult GRITs other than those listed in Tables 9, 10, and 11.


The expression of any number of RITs, IRITs, GRITs, GRIT-like transcripts, tGRITs, oGRITs, or nucleic acids listed in Tables 2, 4, 5, 7, 9, 10, and/or 11 can be evaluated to determine whether or not transplanted tissue will be rejected. For example, the expression of one or more than one (e.g., two, three, four, five, six, seven, eight, nine, ten, 15, 20, 25, 30, 40, 50, 75, 100, or more than 100) of the nucleic acids listed in Table 2 can be used. In some embodiments, determining that a nucleic acid listed in Table 2 is expressed in a sample at a detectable level can indicate that the transplanted tissue will be rejected. In some embodiments, transplanted tissue can be evaluated by determining whether or not the tissue contains cells that express a nucleic acid listed in Table 2 at an elevated level, i.e., a level that is greater than the average expression level observed in control cells obtained from tissue that has not been transplanted. Typically, a nucleic acid can be classified as being expressed at a level that is greater than the average level observed in control cells if the expression levels differ by at least 1-fold (e.g., 1.5-fold, 2-fold, 3-fold, or more than 3-fold). Control cells typically are the same type of cells as those being evaluated. In some cases, the control cells can be isolated from kidney tissue that has not been transplanted into a mammal. Any number of tissues can be used to obtain control cells. For example, control cells can be obtained from one or more tissue samples (e.g., at least 5, 6, 7, 8, 9, 10, or more tissue samples) obtained from one or more healthy mammals (e.g., at least 5, 6, 7, 8, 9, 10, or more healthy mammals).


Any suitable method can be used to determine whether or not a particular nucleic acid is expressed at a detectable level or at a level that is greater than the average level of expression observed in control cells. For example, expression of a particular nucleic acid can be measured by assessing mRNA expression. mRNA expression can be evaluated using, for example, northern blotting, slot blotting, quantitative reverse transcriptase polymerase chain reaction (RT-PCR), real-time RT-PCR, or chip hybridization techniques. Methods for chip hybridization assays include, without limitation, those described herein. Such methods can be used to determine simultaneously the relative expression levels of multiple mRNAs. Alternatively, expression of a particular nucleic acid can be measured by assessing polypeptide levels. For example, polypeptide levels can be measured using any method such as immuno-based assays (e.g., ELISA), western blotting, or silver staining.


The methods and materials provided herein can be used at any time following a tissue transplantation to determine whether or not the transplanted tissue will be rejected. For example, a sample obtained from transplanted tissue at any time following the tissue transplantation can be assessed for the presence of cells expressing elevated levels of a nucleic acid listed in Table 2. In some cases, a sample can be obtained from transplanted tissue 1, 2, 3, 4, 5, 6, 7, 8, or more hours after the transplanted tissue was transplanted. In some cases, a sample can be obtained from transplanted tissue one or more days (e.g., 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 40, or more days) after the transplanted tissue was transplanted. Typically, a sample can be obtained from transplanted tissue 2 to 7 days (e.g., 5 to 7 days) after transplantation and assessed for the presence of cells expressing elevated levels of one or more RITs or expressing elevated levels of one or more nucleic acids listed in Table 2.


This description also provides nucleic acid arrays. The arrays provided herein can be two-dimensional arrays, and can contain at least 10 different nucleic acid molecules (e.g., at least 20, at least 30, at least 50, at least 100, or at least 200 different nucleic acid molecules). Each nucleic acid molecule can have any length. For example, each nucleic acid molecule can be between 10 and 250 nucleotides (e.g., between 12 and 200, 14 and 175, 15 and 150, 16 and 125, 18 and 100, 20 and 75, or 25 and 50 nucleotides) in length. In addition, each nucleic acid molecule can have any sequence. For example, the nucleic acid molecules of the arrays provided herein can contain sequences that are present within the nucleic acids listed in Table 2, Table 4, Table 5, Table 7, Table 9, Table 10, and/or Table 11. For the purpose of this document, a sequence is considered present within a nucleic acid listed in, for example, Table 2 when the sequence is present within either the coding or non-coding strand. For example, both sense and anti-sense oligonucleotides designed to human Abp1 nucleic acid are considered present within Abp1 nucleic acid.


Typically, at least 25% (e.g., at least 30%, at least 40%, at least 50%, at least 60%, at least 75%, at least 80%, at least 90%, at least 95%, or 100%) of the nucleic acid molecules of an array provided herein contain a sequence that is (1) at least 10 nucleotides (e.g., at least 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 25, or more nucleotides) in length and (2) at least about 95 percent (e.g., at least about 96, 97, 98, 99, or 100) percent identical, over that length, to a sequence present within a nucleic acid listed in Table 2, Table 4, Table 5, Table 7, Table 9, Table 10, or Table 11. For example, an array can contain 100 nucleic acid molecules located in known positions, where each of the 100 nucleic acid molecules is 100 nucleotides in length while containing a sequence that is (1) 30 nucleotides in length, and (2) 100 percent identical, over that 30 nucleotide length, to a sequence of one of the nucleic acids listed in Table 2. A nucleic acid molecule of an array provided herein can contain a sequence present within a nucleic acid listed in Table 2, where that sequence contains one or more (e.g., one, two, three, four, or more) mismatches.


The nucleic acid arrays provided herein can contain nucleic acid molecules attached to any suitable surface (e.g., plastic or glass). In addition, any method can be use to make a nucleic acid array. For example, spotting techniques and in situ synthesis techniques can be used to make nucleic acid arrays. Further, the methods disclosed in U.S. Pat. Nos. 5,744,305 and 5,143,854 can be used to make nucleic acid arrays.


Computer-Readable Medium and an Apparatus for Predicting Rejection


This disclosure further provides a computer-readable storage medium configured with instructions for causing a programmable processor to determine whether a transplanted tissue is being or is likely to be rejected. The determination of whether a transplanted tissue is being or will be rejected can be carried out as described herein; that is, by determining whether one or more of the nucleic acids listed in Table 2 or Table 11 is detected in a sample (e.g., a sample of the tissue), or is expressed at a level that is greater than the level of expression in a corresponding tissue that is not transplanted. The processor also can be designed to perform functions such as removing baseline noise from detection signals.


Instructions carried on a computer-readable storage medium (e.g., for detecting signals) can be implemented in a high level procedural or object oriented programming language to communicate with a computer system. Alternatively, such instructions can be implemented in assembly or machine language. The language further can be compiled or interpreted language.


The nucleic acid detection signals can be obtained using an apparatus (e.g., a chip reader) and a determination of tissue rejection can be generated using a separate processor (e.g., a computer). Alternatively, a single apparatus having a programmable processor can both obtain the detection signals and process the signals to generate a determination of whether rejection is occurring or is likely to occur. In addition, the processing step can be performed simultaneously with the step of collecting the detection signals (e.g., “real-time”).


Any suitable process can be used to determine whether a transplanted tissue is being or is likely to be rejected. In some embodiments, for example, a process can include determining whether a pre-determined number (e.g., one, two, three, four, five, six, seven, eight, nine, ten, 15, 20, 25, 30, 40, 50, 75, 100, or more than 100) of the nucleic acids listed in Table 2 or Table 11 is expressed in a sample (e.g., a sample of transplanted tissue) at a detectable level. If the number of nucleic acids that are expressed in the sample is equal to or exceeds the pre-determined number, the transplanted tissue can be predicted to be rejected. If the number of nucleic acids that are expressed in the sample is less than the pre-determined number, the transplanted tissue can be predicted to not be rejected. The steps of this process (e.g., the detection, or non-detection, of each of the nucleic acids listed in Table 2 or Table 11) can be carried out in any suitable order. In some embodiments, a process can include determining whether a pre-determined number of the nucleic acids listed in Table 2 or Table 11 is expressed in a sample at a level that is greater than the average level observed in control cells (e.g., cells obtained from tissue that has not been transplanted. If the number of nucleic acids having increased levels of expression in the sample is equal to or exceeds the pre-determined number, the transplanted tissue can be predicted to be rejected. If the number of nucleic acids having increased expression levels in the sample is less than the pre-determined number, the transplanted tissue can be predicted to not be rejected. Again, the steps of this process can be carried out in any suitable order.


Also provided herein, therefore, is an apparatus for determining whether a transplanted tissue is being or is likely to be rejected. An apparatus for determining whether tissue rejection will occur can include one or more collectors for obtaining signals from a sample (e.g., a sample of nucleic acids hybridized to nucleic acid probes on a substrate such as a chip) and a processor for analyzing the signals and determining whether rejection will occur. By way of example, the collectors can include collection optics for collecting signals (e.g., fluorescence) emitted from the surface of the substrate, separation optics for separating the signal from background focusing the signal, and a recorder responsive to the signal, for recording the amount of signal. The collector can obtain signals representative of the presence of one or more nucleic acids listed in Table 2 or Table 11 (e.g., in samples from transplanted and/or non-transplanted tissue). The apparatus further can generate a visual or graphical display of the signals, such as a digitized representation. The apparatus further can include a display. In some embodiments, the apparatus can be portable.


The invention will be further described in the following examples, which do not limit the scope of the invention described in the claims.


EXAMPLES
Example 1
Interactions Between IFN-γ-Induced Transcripts and Injury Effects

The roles of IFN-γ were investigated in a mouse kidney allograft model that develops the pathologic lesions that are diagnostic in human graft rejection. Basically, a comparison of mouse kidney pathology to the mouse transcriptome was used to guide understanding of the relationship of lesions to transcriptome changes in human rejection. Recombinant IFN-γ (rIFN-γ) was administered to WT mice to identify the GITs in the kidney and examined how the GITs changed during graft rejection, comparing WT to IFN-γ deficient grafts. These experiments have provided insight into some of the complex relationships between IFN-γ inducibility during rejection and in tissue injury and regulation of GITs by non IFN-γ dependent factors during kidney transplantation.


Materials and Methods


Mice: Male CBA/J (CBA) and C57Bl/6 (B6) mice were obtained from the Jackson Laboratory (Bar Harbor, Me.). IFN-γ deficient mice (BALB/c.GKO) and (B6.129S7-IFNgtm1Ts; B6.GKO) were bred in the Health Sciences Laboratory Animal Services at the University of Alberta. Mice maintenance and experiments were in conformity with approved animal care protocols. CBA (H-2K, I-Ak) into C57Bl/6 (B6; H-2KbDb, I-Ab) mice strain combinations, BALB/c.GKO into B6.GKO were studied across full MHC and non-MHC disparities.


Renal transplantation: Renal transplantation was performed as a non life-supporting transplant model. Recovered mice were killed at day 5, 7, 14, 21 or 42 post-transplant. Kidneys were removed, snap frozen in liquid nitrogen and stored at −70° C. No mice received immunosuppressive therapy. Kidneys with technical complications or infection at the time of harvesting were removed from the study.


Treatment with recombinant IFN-γ. CBA mice were injected i.p with 300,000 I.U. of recombinant INF-γ at 0 and 24 hours. rIFN-γ was a generous gift from Dr. T. Stewart at Genentech (South San Francisco, Calif.). Mice were sacrificed after 48 hours.


Microarrays: High-density oligonucleotide Genechip 430A and 430 2.0 arrays, GeneChip T7-Oligo(dT) Promotor Primer Kit, Enzo BioArray HighYield RNA Transcript Labeling Kit, IVT Labeling KIT, GeneChip Sample Cleanup Module, IVT cRNA Cleanup Kit were purchased from Affymetrix (Santa Clara, Calif.). RNeasy Mini Kit was from Qiagen (Ont, Canada), Superscript II, E. coli DNA ligase, E. coli DNA polymerase I, E. coli Rnase H, T4 DNA polymerase, 5× second strand buffer, and dNTPs were from Invitrogen Life Technologies.


RNA preparation and hybridization: Total RNA was extracted from individual kidneys using the guanidinium-cesium chloride method and purified RNA using the RNeasy Mini Kit (Quiagen, Ont. Canada). RNA yields were measured by UV absorbance. The quality was assessed by calculating the absorbance ratio at 260 nm and 280 nm, as well as by using an Agilent BioAnalyzer to evaluate 18S and 28S RNA integrity.


For each array, RNA from 3 mice was pooled. RNA processing, labeling and hybridization to MOE430A or MOE430 2.0 arrays was carried out according to the protocols included in the Affymetrix GeneChip Expression Analysis Technical Manual (available on the World Wide Web at affymetrix.com). cRNA used for Moe 430 2.0 arrays was labeled and fragmented using an IVT Labeling Kit and IVT cRNA Cleanup Kit.


Sample designation: Normal control kidneys were obtained from CBA mice and designated as NCBA. Allografts rejecting in wild type hosts (B6) at day 5 through day 42 post transplant were designated as WT D5, D7, D14, D21 and D42, respectively. Corresponding isografts were designated Iso D5, D7 and D21. Kidneys from mice treated with recombinant IFN-γ and harvested after 48 h were designated rIFN-γ. BALB/c-GKO kidneys (deficient in IFN-7) rejecting in IFN-γ-deficient B6 hosts at day 5 were designated as GKO D5 and corresponding isografts were designated ISO.GKO D5. The following samples (each consisting of RNA pooled from 3 mice) were analyzed by the Moe 430A arrays: two biological replicates of Iso D7, WT (D7, D14, D21 and D42); three replicates for NCBA and WT D5, single samples for Iso D5 and D21. Samples analyzed by the Moe 430 2.0 were NCBA (three replicates), WT D5, GKO D5, ISO.GKO D5 and rIFN-γ (two replicates each).


Sample analysis: Microarray Suite Expression Analysis 5.0 software was used for analysis of Moe 430A arrays (MAS 5.0, Affymetrix), and Gene Chip Operating software (GCOS 2.0, Affymetrix) was used for analysis of Moe 430 2.0 arrays to calculate absolute signal strength and transcripts flagging. Normalization per chip and per gene (GeneSpring™ 7.2, Agilent, Palo Alto Calif.) and to the control samples (NCBA) were described previously. The mean normalized value for further analysis of replicate samples.


Transcripts of interest were selected based on 2-fold differences and significance by Welch's t-test (Anova parametric test, variances not assumed equal). Groups of selected transcripts were then compared for individual time points using the univariate analysis of variance (Unianova with Bonferroni post hoc tests, for log transformed normalized data, SSPS 1.0 statistical package).


Hierarchical cluster analysis was performed using GeneSpring 7.2. Data were log transformed and similarity of transcript expression between experimental groups and between individual transcripts was visualized by a condition and gene tree diagram. Similarity measurements were based on distance. Trajectory clustering (expression pattern comparison, 0.95 correlation coefficient) was performed using the “find similar gene” feature in GeneSpring package.


Results


Terminology: rIFN-γ induced transcripts (GITs) were identified as those increased 48 hours after two injections of rIFN-7, spaced 24 hours apart. Rejection induced transcripts (RITs) were identified as those increased in allografts at day 5. Injury-induced transcripts were identified as those induced in isografts at days 5 and/or 7. The rejection induced transcripts thus include effects of transplant-related stress as well as alloimmune related changes.


Identification of transcripts induced by IFN-γ in vivo in rejecting kidney allografts. Identification of IFN-γ induced transcripts in kidney allografts was based on data obtained from the Moe 430 2.0 arrays, with cytotoxic T lymphocyte associated transcripts (CATs) deleted from all lists to avoid overlap. First, the rIFN-γ-induced transcripts were identified: 342 transcripts flagged present and increased 2-fold in normal kidneys from mice treated with rIFN-γ (significant by ANOVA) (Table 1). RITs were then selected, defined as transcripts that were elevated 2-fold in WT allografts at day 5 post transplant in WT hosts vs. normal kidneys (significant by Anova). 2040 transcripts, flagged present in the allografts, fulfilled these criteria (Table 2). To determine how many of these transcripts were IFN-γ inducible, they were compared to the GITs. This comparison yielded 163 common transcripts that were induced by rIFN-γ treatment and increased in rejecting kidneys at day 5. Thus, 179 GITs were not significantly induced in rejecting kidneys by these criteria, in spite of the strong IFN-γ response in the allograft.


Validation of IFN-γ induced transcripts in mouse kidney allografts: To verify that the increased expression of 163 transcripts in day 5 allografts was at least partially dependent on IFN-γ, IFN-γ-deficient kidney allografts grafted into IFN-γ-deficient hosts were studied. In these grafts, neither the donor nor the host cells can make IFN-γ. After removing CATs, 570 transcripts were expressed at least 2-fold lower in GKO D5 compared to WT D5 (significant by ANOVA), indicating that the expression of these transcripts was affected by the presence or absence of IFN-γ in allografts (Table 3). Of the 163 previously defined rIFN-γ- and rejection-induced transcripts, 74 were decreased in GKO D5, indicating that they were at least partially dependent on IFN-γ in WT D5 allografts. These were termed IFN-γ and rejection-inducible transcripts (GRITs). On the other hand, 89 transcripts, despite being rIFN-γ-inducible, were not lower or were even increased when IFN-γ was absent in GKO D5 allografts compared to WT D5 allografts. These were termed GRIT-like transcripts. Thus, the GRIT-like transcripts, despite being inducible by rIFN-γ, were increased in allografts by mechanisms largely independent of IFN-γ. The algorithm used for transcript selection is shown in FIG. 1.


Functional classification of GRIT and GRIT-like: The list of GRITs (Table 4) summarizes local effects of IFN-γ on transcription in the isografts and the allografts, as well as systemic effects on the normal rejecting kidney. The transcripts represent genes for several major classes of proteins: (a) MHCs and their related factors (B2m Psmb8-9, Tapbp) and other ubiquitination/proteolysis-related factors (Parp14, Psmb10, Ubd, Ub11); (b) guanylate binding proteins (Gbp2), interferon-induced GTPases (Igtp, Iigp1, Tgtp) and other so called IFN-γ-induced proteins (Ifi1 and Ifi47); (c) cytokines and chemokines: Cc15, Cc18, Cxc19, Cxc110, interleukin-18 binding protein (I118 bp), Arts1; (d) other immune functions: complement components (C1r, C1s, C2); and (e) transcription factors and activators: Irf7 (ISRE sites), Stat1 (GAS sites), class II transactivator C2ta.


The list of GRIT-like transcripts (Table 5) includes complement components (C1qb, C1qg, Serping1); cytokine, chemokine and receptor related transcripts (Tnfsf13b, Ccr5, Cxci 14, Socs2); some interferon-induced transcripts (Ifi27, Ifitm1, Ifitm6); and Tgfbi, a transcript whose expression is regulated by Tgfb1.


Expression profiles of GRIT and GRIT-like in the isografts and the allografts: The time course of changes in these transcripts post transplant was studied by querying a previously established database from MOE 430A arrays containing the expression values of all transcripts in isografts and allografts, at different times post transplant. Previously identified GRITs were “translated” (using the GeneSpring translation feature) to Moe 430A arrays, and these increased at least 2 fold (significant by Anova) in WT D5 allografts vs NCBA were selected. This permitted creation of a final list of 59 GRITs (Table 4) and 42 GRIT-like transcripts (Table 5). The lower number of transcripts was due to a lack of certain probe sets interrogating Riken sequences in Moe 430A arrays, and perhaps also to the lower sensitivity of the M430A arrays.


Analysis of the expression time course of GRITs and GRIT-like transcripts in isografts and allografts permitted comparison of the impact of transplant-related stress and/or injury on rejection. First, unsupervised clustering of all isografts and allografts was performed based on GRITs and GRIT-like lists (FIG. 2 and FIG. 3). Kidney samples were grouped into two clusters. One powerful cluster included all of the allografts, indicating strong and consistent expression of the GRITs and GRIT-like transcripts in all allografts at all times tested. Surprisingly, ISO D5 clustered with all allografts for the GRITs (FIG. 2). ISO D21 co-clustered with NCBA, indicating recovery of kidneys from injury. ISO D7 was more similar to this group. On the other hand, GRIT-like list yielded good separation of the all isografts from the allografts, clustering ISO D5 and ISO D7 in one subgroup (FIG. 3). This indicated a stronger relation of GRIT expression in ISO D5 to rejecting allografts, compared to GRIT-like expression.


Time course of GRIT expression parallels IFN-γ expression: The time course of GRIT expression supported the cluster organization and the conclusion that there were differences in regulation of GRITs (FIG. 2) versus GRIT-like transcripts (FIG. 3). In the isografts, expression of many GRITs peaked at D5 post transplant and sharply declined at D7 and D21. Thirty-nine and 11 GRITs were increased at least 2-fold at ISO D5 and ISO D7, respectively. Mean expression of GRITs in ISO D5 samples was higher than in ISO D7 and D21 (p<0.01). GRIT expression in the allografts, however, was sustained throughout the observation period, with no significant differences among the samples except for a small peak at D14 (p<0.05). In addition, GRIT expression in the allografts showed 4-fold higher mean expression compared to ISO D5 (p<0.02, corrected for multiple comparisons).


For the comparison, FIG. 2A demonstrates the time course of IFN-γ expression in the isografts D5 throughout D21 and the allografts day 5 throughout day 42. Isograft IFN-γ transcript levels peaked at D5 and declined from D7 on (FIGS. 2B and 2C). However, IFN-γ transcript levels were 5-fold higher in WT D5 allografts compared to ISO D5, and remained high at all allograft time points, with some increase at day 14. Thus GRIT expression parallels that of IFN-γ.


IFN-γ expression also was assessed in WT allografts at early times post transplant. IFN-γ signal strength increased about 8 fold in D5 compared to D3 allografts (FIG. 4A), indicating that the IFN-γ expression was established at D5 post transplant.


Time course of GRIT-like transcripts parallels TGF-β1 expression: GRIT-like transcripts were analyzed over the time course shown in FIG. 3A, and showed consistent expression in all allografts. However, they differed in isografts: there was no statistically significant difference between their mean expression at ISO D5 and ISO D7 (FIG. 3B). 17 GRIT-like allografts were increased at least 2-fold either in ISO D5 or ISO D7 samples. Mean GRIT-like expression was 2 fold higher compared to ISO D5 or ISO D7 (p<0.02, corrected for multiple comparisons). However, GRIT-like mean expression in the isografts and the allografts was lower by 2-fold compared to GRITs.


The appearance of Tgfbi in the GRIT-like list suggests that Tgfb1 may be playing a role in the regulation of some of these transcripts. Moreover, the GRIT-like transcripts, by definition, are not significantly reduced in the absence of IFN-γ, indicating that they are induced by other factors, one candidate being Tgf-β1. The expression profile of Tgfbi was reminiscent of Tgfb1, i.e., it demonstrated a similar peak in ISO D7 and strong increase in the allografts, like many of the GRIT-like transcripts.


The expression time course of GRIT/GRIT-like in WT allografts at early times post transplant demonstrated a step-wise increase from day 3 to day 4 to day 5 post transplant (FIGS. 4B and 4C).


Expression of GRITs and GRIT-like in the isografts differ in response to IFN-γ: To confirm that the elevated expression of GRIT in wild type isografts is dependent on IFN-7, the expression of GRITs was assessed in the IFN-γ-deficient D5 isografts (ISO.GKO D5) by Moe 430 2.0 arrays and compared to GRIT expression in wild type isografts D5. Transcripts that were increased at least 2-fold in WT D5 vs to ISO.GKO D5 were translated to Moe 430A arrays. It was observed that 36 out of 59 GRITs (Table 4) were expressed at least 2-fold higher in WT D5 isografts compared to ISO.GKO D5. Notably, only 10 GRIT-like transcripts fulfilled these criteria (Table 5). Thus, the majority (66%) of GRITs and only a fraction (25%) of GRIT-like transcripts seemed to be dependent on IFN-γ produced in the isografts.


Regulation of the expression of injury and rejection induced transcripts that are not IFN-γ regulated by these criteria: Due to the uniformity with which the GRITs and GRIT-like transcripts were increased in the isografts (albeit to a varying degree in ISO D5 and ISO D7 samples), the analysis of transplant stress/injury to rejection was extended by analyzing all transcripts flagged present and elevated 2-fold either in isografts at days 5 or 7 and increased 2-fold in WT D5 (significant by Anova). GRITs, GRIT-like and CATs were eliminated from this list. Moreover, transcripts were detected that were decreased 2-fold or more in GKO D5 compared to WT D5, but were not affected by rIFNγ administration. One hundred ten of these transcripts translated to Moe 430A arrays (Table 6) and were eliminated from the RIT list.


The analysis yielded many transcripts that behaved like the GRIT-like transcripts, with a peak at day 7 and consistent high expression in all allografts. As listed in Table 7, 147 injury-induced RITs met these conditions in Moe 430A database. Unsupervised clustering based on this list grouped ISO D7 samples with the allografts (FIG. 5A). Expression pattern of these transcripts confirmed the clustering result. Injury-induced RITs peaked in ISO D7 isografts rather than ISO D5 (FIG. 5B; significant by Anova). One hundred forty RITs were increased 2-fold or more at ISO D7, including the acute-phase response markers: serum amyloids 1-3 and ceruloplasmin, while 54 were increased at ISO D5. The mean expression of RITs was more elevated and sustained in the allografts compared to ISO D7 and ISO D5, with a peak in WT D14 allografts (FIG. 5B, significant by Anova). A Medline-assisted literature search revealed that expression of the injury-induced RITs transcripts could be dependent on either IFN-γ or Tgfb1, or both. IFN-γ control was reported for Vim, Cc12, Arrb2 (also reported as a possible marker of human heart rejection), ceruloplasmin, Fn1, Fos, Socs3, Timp1, Ncf2, Fcgr3, Plek, and Casp12. Tgfb1 control was reported for transcripts Tgfbi, collagen type 1a2 and 3a1, Socs3, Lox, Cspg2, Fn1, Postn (periostin, homologous to Tgfbi) (Table 8).


The expression profiles of these transcripts were then analyzed, and it was observed that the average expression pattern of injury-induced RITs was significantly similar to the Tgfbi expression profile, as assessed by the trajectory profiling i.e. “find similar gene(s)” feature of GeneSpring (FIGS. 6A and 6B). Next, the expression profiles of a selected prototypic GRIT (Stat1, which was elevated in isografts) and a prototypic GRIT-like transcript (Tgfbi) were compared to the expression profiles of injury-induced RITs. Using the trajectory clustering, 50 transcripts were found with patterns similar to that of Tgfbi (FIG. 7A), and 43 transcripts were found with patterns similar to that of STAT-1 (FIG. 7B). RITs showing Stat-1-like profiles had substantial overlap (39 transcripts) with Tgfbi-like profiles.









TABLE 1







rIFN-γ-induced transcripts (GITs)














rIFNg



Gene Symbol

NCBA
vs


Affymetrix
Gene Title Affymetrix
Raw
NCBA
Genbank














—
—
1241
3.2
AV290571


—
—
855
3.0
AV227574


—
—
12
2.2
BB416480


—
—
127
2.0
BB291656


—
—
219
3.0
BB533460


—
—
25
2.8
AW554440


—
—
83
2.3
BB308208


Oasl2
2′-5′ oligoadenylate synthetase-like 2
209
2.2
BQ033138


Hmgcr
3-hydroxy-3-methylglutaryl-Coenzyme A
291
2.8
BB123978



reductase


Hmgcs2
3-hydroxy-3-methylglutaryl-Coenzyme A
83
5.8
BC014714



synthase 2


Arf3
ADP-ribosylation factor 3
107
2.6
BQ175059


Akr1c18
aldo-keto reductase family 1, member C18
314
7.9
NM_134066


Akr1c20
aldo-keto reductase family 1, member C20
28
15.8
BC021607


Angptl3
angiopoietin-like 3
253
3.7
BC019491


Arg2
arginase type II
85
9.3
AV002218


Arvcf
armadillo repeat gene deleted in velo-
153
2.0
BE947943



cardio-facial syndrome


Astn1
astrotactin 1
21
2.7
NM_007495


Atp8a1
ATPase, aminophospholipid transporter
150
2.1
BQ176779



(APLT), class I, type 8A, member 1


Atp1a2
ATPase, Na+/K+ transporting, alpha 2
33
3.3
AV325919



polypeptide


Abcb1a
ATP-binding cassette, sub-family B
40
3.9
M30697



(MDR/TAP), member 1A


Abcb1a
ATP-binding cassette, sub-family B
142
3.8
M30697



(MDR/TAP), member 1A


Abcc3
ATP-binding cassette, sub-family C
130
17.7
AK006128



(CFTR/MRP), member 3


Bhlhb5
basic helix-loop-helix domain containing,
113
2.0
NM_021560



class B5


B2m
beta-2 microglobulin
9650
2.6
AI099111


B2m
beta-2 microglobulin
71
3.5
AA170322


B2m
beta-2 microglobulin
13469
2.0
BF715219


Bhmt
betaine-homocysteine methyltransferase
331
9.6
NM_016668


Bace
beta-site APP cleaving enzyme
152
4.1
BB114336


Baat
bile acid-Coenzyme A: amino acid N-
17
11.2
NM_007519



acyltransferase


Cdh11
cadherin 11
381
2.0
NM_009866


Car5a
carbonic anhydrase 5a, mitochondrial
98
2.2
NM_007608


Cart1
cartilage homeo protein 1
57
2.4
BB366930


Ctss
cathepsin S
838
2.6
NM_021281


BC011209
cDNA sequence BC011209
437
2.0
BC011209


BC021340
cDNA sequence BC021340
256
2.2
BC021340


BC060267
cDNA sequence BC060267
59
2.2
BB124106


Ceacam1
CEA-related cell adhesion molecule 1
296
3.0
M77196


Ceacam1
CEA-related cell adhesion molecule 1
377
2.3
BC016891


Ceacam1
CEA-related cell adhesion molecule 1
670
2.5
NM_011926


Ceacam2
CEA-related cell adhesion molecule 2
100
3.1
NM_007543


Ceacam2
CEA-related cell adhesion molecule 2
733
2.6
BC024320


Cp
ceruloplasmin
232
2.1
BB332449


Ccl21a
chemokine (C—C motif) ligand 21a (serine)
368
2.0
NM_011335


Ccl5
chemokine (C—C motif) ligand 5
34
6.0
NM_013653


Ccl8
chemokine (C—C motif) ligand 8
115
2.3
NM_021443


Ccr5
chemokine (C—C motif) receptor 5
73
2.6
D83648


Cxcl10
chemokine (C—X—C motif) ligand 10
162
2.2
NM_021274


Cxcl12
chemokine (C—X—C motif) ligand 12
1335
2.2
NM_013655


Cxcl14
chemokine (C—X—C motif) ligand 14
260
2.1
AF252873


Cxcl14
chemokine (C—X—C motif) ligand 14
124
2.4
AF252873


Cxcl9
chemokine (C—X—C motif) ligand 9
125
6.5
NM_008599


CRAD-L
cis-retinol/3alpha hydroxysterol short-chain
2243
4.5
BC018263



dehydrogenase-like


C2ta
class II transactivator
89
2.0
AF042158


C1qb
complement component 1, q
363
2.8
NM_009777



subcomponent, beta polypeptide


C1qg
complement component 1, q
185
4.0
NM_007574



subcomponent, gamma polypeptide


C1r
complement component 1, r
148
2.8
BB558917



subcomponent


C1r
complement component 1, r
382
3.1
NM_023143



subcomponent


C1s
complement component 1, s
395
2.3
BC022123



subcomponent


C2
complement component 2 (within H-2S)
1215
2.6
NM_013484


Coro1a
coronin, actin binding protein 1A
168
2.2
BB740218


Coro1a
coronin, actin binding protein 1A
239
2.2
BC002136


Cugbp2
CUG triplet repeat, RNA binding protein 2
161
2.1
BB644164


Cdkn1c
cyclin-dependent kinase inhibitor 1C (P57)
367
2.1
NM_009876


Cox8b
cytochrome c oxidase, subunit VIIIb
47
6.0
NM_007751


Cyp4a10
cytochrome P450, family 4, subfamily a,
573
2.0
BC013476



polypeptide 10


Cyp4a14
cytochrome P450, family 4, subfamily a,
47
148.5
AI327006



polypeptide 14


Dach1
dachshund 1 (Drosophila)
91
2.0
BB522228


Dock10
dedicator of cytokinesis 10
145
2.6
BF715043


D10Bwg1379e
DNA segment, Chr 10, Brigham &
25
3.9
BB125269



Women's Genetics 1379 expressed


D12Ertd647e
DNA segment, Chr 12, ERATO Doi 647,
953
4.9
AW554405



expressed


D12Ertd647e
DNA segment, Chr 12, ERATO Doi 647,
1414
3.4
BI655075



expressed


D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's
52
2.4
BQ175587



Genetics 0562 expressed


D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's
178
3.1
BB238462



Genetics 0562 expressed


D7Bwg0421e
DNA segment, Chr 7, Brigham & Women's
64
2.0
AK017222



Genetics 0421 expressed


Duf6
DUF6 containing protein
112
2.2
BB758319


Edaradd
EDAR (ectodysplasin-A receptor)-
28
3.1
NM_133643



associated death domain


Emr4
EGF-like module containing, mucin-like,
20
3.5
AF396935



hormone receptor-like sequence 4


Elovl2
elongation of very long chain fatty acids
951
2.3
NM_019423



(FEN1/Elo2, SUR4/Elo3, yeast)-like 2


Elovl6
ELOVL family member 6, elongation of
323
3.2
NM_130450



long chain fatty acids (yeast)


Enah
enabled homolog (Drosophila)
81
2.1
AV329519


Ednra
endothelin receptor type A
18
3.6
BC008277


Eva
epithelial V-like antigen
371
2.0
BC015076


Eva
epithelial V-like antigen
490
2.0
BC015076


AI481100
expressed sequence AI481100
365
5.2
NM_019440


AI788959
expressed sequence AI788959
914
2.8
BC028826


AI789751
expressed sequence AI789751
326
9.9
AI789751


AI987712
expressed sequence AI987712
92
28.2
AW554594


AU040377
expressed sequence AU040377
141
2.1
AV024806


AW111922
expressed sequence AW111922
361
8.0
BM239828


AW111922
expressed sequence AW111922
885
7.5
BM239828


AW413625
expressed sequence AW413625
80
2.7
NM_026640


Fabp7
fatty acid binding protein 7, brain
795
2.1
NM_021272


Facl2
fatty acid Coenzyme A ligase, long chain 2
5896
2.3
BC006692


Facl2
fatty acid Coenzyme A ligase, long chain 2
1417
2.1
BI413218


Fer1l3
fer-1-like 3, myoferlin (C. elegans)
208
1.9
BI555209


Fgl2
fibrinogen-like protein 2
114
2.5
BF136544


Foxd1
forkhead box D1
36
2.8
BB662927


Foxq1
forkhead box Q1
219
2.5
NM_008239


Foxq1
forkhead box Q1
142
3.8
AV009267


Gpr135
G protein-coupled receptor 135
45
2.9
AV221890


Gsto1
glutathione S-transferase omega 1
1328
2.1
AV003026


Gpm6b
glycoprotein m6b
232
2.2
AK016567


Gzma
granzyme A
68
3.6
NM_010370


Gc
group specific component
554
6.0
AI195150


Gbp2
guanylate nucleotide binding protein 2
321
23.0
NM_010260


Gbp2
guanylate nucleotide binding protein 2
272
22.9
BE197524


Hck
hemopoietic cell kinase
117
2.1
NM_010407


Hdgfrp3
hepatoma-derived growth factor, related
93
2.6
BB291880



protein 3


H2-Aa
histocompatibility 2, class II antigen A,
2137
4.3
AF119253



alpha


H2-Aa
histocompatibility 2, class II antigen A,
3501
4.3
BE688749



alpha


H2-Ab1
histocompatibility 2, class II antigen A,
421
8.2
M15848



beta 1


H2-Ab1
histocompatibility 2, class II antigen A,
950
7.9
NM_010379



beta 1


H2-Ab1
histocompatibility 2, class II antigen A,
659
10.9
M15848



beta 1


H2-Eb1
histocompatibility 2, class II antigen E beta
1760
3.7
NM_010382


H2-DMa
histocompatibility 2, class II, locus DMa
261
9.0
NM_010386


H2-DMb1
histocompatibility 2, class II, locus Mb1
121
14.5
NM_010388


H2-DMb1
histocompatibility 2, class II, locus Mb1
159
15.2
BB734586


H2-DMb1
histocompatibility 2, class II, locus Mb1
116
8.9
NM_010387


H2-DMb1
histocompatibility 2, class II, locus Mb1
87
20.1
BB734586


H2-DMb1
histocompatibility 2, class II, locus Mb1
347
7.4
NM_010388


H2-K
histocompatibility 2, K region
626
10.3
L23495


H2-T10
histocompatibility 2, T region locus 10
2355
2.3
NM_010395


H2-T23
histocompatibility 2, T region locus 23
2198
5.2
NM_010398


Hist1h2ae
histone 1, H2ae
525
2.3
W91024


Hoxd3
homeo box D3
127
1.9
J03770


Hrasls3
HRAS like suppressor 3
504
6.9
BC024581


Hrasls3
HRAS like suppressor 3
372
7.1
BB404920


Hpgd
hydroxyprostaglandin dehydrogenase 15
556
2.7
AV026552



(NAD)


9830126M18
hypothetical protein 9830126M18
113
2.0
BM224662


A330067P21
hypothetical protein A330067P21
65
2.0
BG085812


A330075D07
hypothetical protein A330075D07
34
2.7
BB193024


D630002G06
hypothetical protein D630002G06
712
6.1
AB056443


D630002G06
hypothetical protein D630002G06
650
5.4
AB056443


D630002G06
hypothetical protein D630002G06
136
3.6
NM_134256


D730019B10
hypothetical protein D730019B10
23
2.5
BB508669


MGC6357
hypothetical protein MGC6357
68
2.2
BB667558


Ii
Ia-associated invariant chain
3790
4.3
BC003476


Idb3
inhibitor of DNA binding 3
1075
2.1
NM_008321


Idb4
inhibitor of DNA binding 4
175
2.1
BB306828


Idb4
inhibitor of DNA binding 4
1179
2.2
BB121406


Igf1
insulin-like growth factor 1
398
2.1
BG092677


Igfals
insulin-like growth factor binding protein,
214
2.4
NM_008340



acid labile subunit


Itga6
integrin alpha 6
2198
2.0
BM935811


Itgax
integrin alpha X
80
2.6
NM_021334


Igtp
interferon gamma induced GTPase
905
5.6
NM_018738


Ifi1
interferon inducible protein 1
1151
3.8
NM_008326


Irf7
interferon regulatory factor 7
198
4.0
NM_016850


G1p2
interferon, alpha-inducible protein
112
3.3
AK019325


Ifit1
interferon-induced protein with
93
6.2
NM_008331



tetratricopeptide repeats 1


Ifit2
interferon-induced protein with
271
2.9
NM_008332



tetratricopeptide repeats 2


Il18bp
interleukin 18 binding protein
122
12.2
AF110803


Kcnip2
Kv channel-interacting protein 2
94
2.8
AW490636


Kcnip2
Kv channel-interacting protein 2
28
2.8
AF439339


Kynu
kynureninase (L-kynurenine hydrolase)
202
4.1
AV227891


Lrp8
low density lipoprotein receptor-related
84
2.8
BB750940



protein 8, apolipoprotein e receptor


Ly6e
lymphocyte antigen 6 complex, locus E
1793
3.2
BM245572


Ly6f
lymphocyte antigen 6 complex, locus F
24
7.1
NM_008530


—

M. musculus mRNA for testis-specific
4515
2.1
AV148480



thymosin beta-10


Mpeg1
macrophage expressed gene 1
402
4.5
L20315


Mme
membrane metallo endopeptidase
2038
2.0
AV174022


Ms4a11
membrane-spanning 4-domains, subfamily
50
2.3
NM_026835



A, member 11


Ms4a4d
membrane-spanning 4-domains, subfamily
96
2.6
NM_025658



A, member 4D


Ms4a6b
membrane-spanning 4-domains, subfamily
126
2.8
NM_027209



A, member 6B


—
MHC I = H-2Kd homolog {alternatively
435
10.0
S70184



spliced, deletion of exon 3} [mice, DBA/2,



L1210 lymphoma, mRNA Mutant, 855 nt]


Mmd
monocyte to macrophage differentiation-
662
2.3
BC021914



associated


—

Mus musculus 0 day neonate head cDNA,
420
2.5
BB109391



RIKEN full-length enriched library,



clone: 4833430O13 product: unknown EST,



full insert sequence


—

Mus musculus 0 day neonate kidney
39
2.3
BB500101



cDNA, RIKEN full-length enriched library,



clone: D630024M22 product: unclassifiable,



full insert sequence


—

Mus musculus 0 day neonate kidney
153
2.1
BB820846



cDNA, RIKEN full-length enriched library,



clone: D630033M22 product: hypothetical



protein, full insert sequence


—

Mus musculus 0 day neonate kidney
54
2.9
BB504342



cDNA, RIKEN full-length enriched library,



clone: D630047M14 product: unclassifiable,



full insert sequence


—

Mus musculus 0 day neonate lung cDNA,
70
2.0
BI452538



RIKEN full-length enriched library,



clone: E030022N22 product: unclassifiable,



full insert sequence


—

Mus musculus 0 day neonate thymus
112
2.7
AK020789



cDNA, RIKEN full-length enriched library,



clone: A430110A21 product: unclassifiable,



full insert sequence


—

Mus musculus 10 days neonate
38
2.7
BM201103



cerebellum cDNA, RIKEN full-length



enriched library, clone: B930059K21



product: unknown EST, fuil insert sequence


—

Mus musculus 12 days embryo spinal
56
2.0
BB454099



ganglion cDNA, RIKEN full-length enriched



library, clone: D130028L22



product: unclassifiable, full insert sequence


—

Mus musculus 16 days embryo head
110
2.3
BB208251



cDNA, RIKEN full-length enriched library,



clone: C130051K14 product: unknown EST,



full insert sequence


—

Mus musculus 16 days embryo head
71
2.6
BB374879



cDNA, RIKEN full-length enriched library,



clone: C130077H22 product: unclassifiable,



full insert sequence


—

Mus musculus 16 days neonate
128
2.1
AV118079



cerebellum cDNA, RIKEN full-length



enriched library, clone: 9630032E14



product: unknown EST, full insert sequence


—

Mus musculus 16 days neonate thymus
56
2.4
BB162048



cDNA, RIKEN full-length enriched library,



clone: A130086M19 product: unknown EST,



full insert sequence


—

Mus musculus 18-day embryo whole body
157
2.2
BM730637



cDNA, RIKEN full-length enriched library,



clone: 1110059G02 product: unclassifiable,



full insert sequence


—

Mus musculus 2 days pregnant adult
55
2.2
BB053468



female oviduct cDNA, RIKEN full-length



enriched library, clone: E230038I17



product: unknown EST, full insert sequence


—

Mus musculus 3 days neonate thymus
172
2.8
BI151331



cDNA, RIKEN full-length enriched library,



clone: A630040D01 product: unknown EST,



full insert sequence


—

Mus musculus 4 days neonate male
87
2.0
BB326079



adipose cDNA, RIKEN full-length enriched



library, clone: B430203I24



product: unknown EST, full insert sequence


—

Mus musculus 6 days neonate head
85
2.1
AK017417



cDNA, RIKEN full-length enriched library,



clone: 5430440L12 product: unknown EST,



full insert sequence


—

Mus musculus 7 days embryo whole body
124
2.2
BB408240



cDNA, RIKEN full-length enriched library,



clone: C430005H19 product: unknown EST,



full insert sequence


—

Mus musculus adult male bone cDNA,
55
2.3
BB134628



RIKEN full-length enriched library,



clone: 9830116N24 product: unclassifiable,



full insert sequence


—

Mus musculus adult male corpora
64
2.6
AI323288



quadrigemina cDNA, RIKEN full-length



enriched library, clone: B230339M22



product: inhibitor of DNA binding 4, full



insert sequence


—

Mus musculus adult male medulla
26
2.2
AV332226



oblongata cDNA, RIKEN full-length



enriched library, clone: 6330531L09



product: unknown EST, full insert sequence


—

Mus musculus adult male olfactory brain
26
1.9
AV237721



cDNA, RIKEN full-length enriched library,



clone: 6430566E03 product: unknown EST,



full insert sequence


—

Mus musculus Corpos mRNA, 3′
59
2.2
BM220939



untranslated region


—

Mus musculus NOD-derived CD11c +ve
223
2.1
AK004894



dendritic cells cDNA, RIKEN full-length



enriched library, clone: F630107D10



product: similar to UBIQUITIN-



ACTIVATING ENZYME E1 [Homo




sapiens], full insert sequence


—

Mus musculus similar to Aldo-keto
907
2.1
BG073853



reductase family 1 member C13



(LOC238465), mRNA


—

Mus musculus similar to hypothetical
716
2.5
BM243674



protein (LOC243374), mRNA


—

Mus musculus similar to hypothetical
25
2.4
BE197771



protein FLJ31208 (LOC225602), mRNA


—

Mus musculus transcribed sequence
31
3.5
AI790337


—

Mus musculus transcribed sequence with
47
3.3
BG063622



strong similarity to protein sp: P00722 (E. coli)



BGAL_ECOLI Beta-galactosidase



(Lactase)


—

Mus musculus transcribed sequence with
44
4.7
BB210623



weak similarity to protein ref: NP_036400.1



(H. sapiens) similar to vaccinia virus



HindIII K4L ORF [Homo sapiens]


—

Mus musculus transcribed sequence with
191
45.8
BM241485



weak similarity to protein sp: P32456



(H. sapiens) GBP2_HUMAN Interferon-



induced guanylate-binding protein 2



(Guanine nucleotide-binding protein 2)


—

Mus musculus transcribed sequences
35
2.5
BB460538


—

Mus musculus transcribed sequences
90
2.1
BB485280


—

Mus musculus transcribed sequences
46
2.0
BM218007


—

Mus musculus transcribed sequences
87
3.4
AV277444


—

Mus musculus transcribed sequences
438
4.5
BE688358


—

Mus musculus transcribed sequences
182
2.1
AW492955


—

Mus musculus transcribed sequences
58
4.5
BI134319


—

Mus musculus transcribed sequences
91
2.0
BB497148


—

Mus musculus transcribed sequences
63
2.4
BG069383


—

Mus musculus transcribed sequences
67
2.1
BM220820


—

Mus musculus transcribed sequences
25
2.2
BB553888


—

Mus musculus transcribed sequences
18
2.2
BB767194


—

Mus musculus transcribed sequences
44
2.0
BM730703


—

Mus musculus transcribed sequences
102
1.9
BG068971


—

Mus musculus transcribed sequences
339
27.6
BG092512


—

Mus musculus transcribed sequences
130
2.0
AW546127


—

Mus musculus transcribed sequences
72
2.3
AW543171


—

Mus musculus transcribed sequences
150
2.1
BI664122


—

Mus musculus transcribed sequences
193
2.0
AV291009


—

Mus musculus transcribed sequences
54
2.0
AU041975


—

Mus musculus transcribed sequences
95
2.0
AV352204


—

Mus musculus transcribed sequences
20
2.1
BB043509


—

Mus musculus transcribed sequences
217
2.0
BM119402


—

Mus musculus transcribed sequences
32
2.5
AV300631


—

Mus musculus transcribed sequences
82
4.6
BG067157


—

Mus musculus transcribed sequences
115
2.2
AW111920


—

Mus musculus transcribed sequences
35
3.5
BM225081


—

Mus musculus transcribed sequences
133
2.0
AW556334


—

Mus musculus transcribed sequences
27
3.0
AI118114


—

Mus musculus transcribed sequences
18
3.1
BB520952


—

Mus musculus transcribed sequences
142
2.2
AV264768


—

Mus musculus, clone IMAGE: 4507681,
32
3.0
BG071655



mRNA


Mll
myeloid/lymphoid or mixed-lineage
128
2.1
AK017541



leukemia


Npnt
nephronectin
1459
2.0
AA223007


Npnt
nephronectin


BB433705


Ntf3
neurotrophin 3
49
3.3
NM_008742


Odz3
odd Oz/ten-m homolog 3 (Drosophila)
9
3.2
BB472509


Olfr56
olfactory receptor 56
336
3.4
NM_008330


Padi2
peptidyl arginine deiminase, type II
110
3.0
NM_008812


Ppicap
peptidylprolyl isomerase C-associated
1079
3.2
NM_011150



protein


Pte2a
peroxisomal acyl-CoA thioesterase 2A
780
2.7
NM_134246


Pck1
phosphoenolpyruvate carboxykinase 1,
46
6.8
BB225177



cytosolic


Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
64
3.0
BI684288


Pigr
polymeric immunoglobulin receptor
3030
2.1
AV027632


Kcnk1
potassium channel, subfamily K, member 1
708
4.0
AU043100


Prickle1
prickle like 1 (Drosophila)
144
2.3
BC022643


Prickle1
prickle like 1 (Drosophila)
40
2.9
BE992966


Pdcd1lg1
programmed cell death 1 ligand 1
73
4.4
NM_021893


Prom1
prominin 1
2598
2.7
NM_008935


Psmb10
proteasome (prosome, macropain)
525
3.2
NM_013640



subunit, beta type 10


Psmb8
proteosome (prosome, macropain)
17
5.1
AV068122



subunit, beta type 8 (large multifunctional



protease 7)


Psmb8
proteosome (prosome, macropain)
461
9.9
NM_010724



subunit, beta type 8 (large multifunctional



protease 7)


Psmb9
proteosome (prosome, macropain)
298
4.5
NM_013585



subunit, beta type 9 (large multifunctional



protease 2)


Arhgef6
Rac/Cdc42 guanine nucleotide exchange
142
2.8
BM246754



factor (GEF) 6


Rai2
retinoic acid induced 2
59
2.0
BB770528


1110004C05Rik
RIKEN cDNA 1110004C05 gene
3701
2.3
BC010291


1110036C17Rik
RIKEN cDNA 1110036C17 gene
622
2.7
BC027285


1110036O03Rik
RIKEN cDNA 1110036O03 gene
115
2.0
BE951265


1110063G11Rik
RIKEN cDNA 1110063G11 gene
81
2.0
AK004359


1190005J19Rik
RIKEN cDNA 1190005J19 gene
31
2.0
NM_007819


1200015N20Rik
RIKEN cDNA 1200015N20 gene
39
2.2
BB461323


1600020H07Rik
RIKEN cDNA 1600020H07 gene
1301
2.7
NM_019975


1700003F17Rik
RIKEN cDNA 1700003F17 gene
64
2.9
AV220213


1700007J06Rik
RIKEN cDNA 1700007J06 gene
27
2.2
AK005720


1700019D03Rik
RIKEN cDNA 1700019D03 gene
20
2.4
AK006110


1810037B05Rik
RIKEN cDNA 1810037B05 gene
50
3.0
AK007714


2010204K13Rik
RIKEN cDNA 2010204K13 gene
249
2.3
NM_023450


2310007B03Rik
RIKEN cDNA 2310007B03 gene
78
2.3
AK009193


2310008H04Rik
RIKEN cDNA 2310008H04 gene
246
5.7
BC026877


2310015I10Rik
RIKEN cDNA 2310015I10 gene
269
5.7
BC008532


2310022A04Rik
RIKEN cDNA 2310022A04 gene
327
2.0
AK007542


2310035M22Rik
RIKEN cDNA 2310035M22 gene
44
2.2
NM_025863


2310046K10Rik
RIKEN cDNA 2310046K10 gene
63
2.2
AK017174


2310046K10Rik
RIKEN cDNA 2310046K10 gene
106
2.1
BF020640


2310061N23Rik
RIKEN cDNA 2310061N23 gene
219
4.2
AY090098


2410041A17Rik
RIKEN cDNA 2410041A17 gene
556
3.4
NM_133348


2510038N07Rik
RIKEN cDNA 2510038N07 gene
161
2.5
AW208668


2610030H06Rik
RIKEN cDNA 2610030H06 gene
510
2.3
BB429625


2700038M07Rik
RIKEN cDNA 2700038M07 gene
786
2.0
BC019601


2810002E22Rik
RIKEN cDNA 2810002E22 gene
543
2.2
NM_133859


2810030E01Rik
RIKEN cDNA 2810030E01 gene
76
2.1
BB255999


3300001H21Rik
RIKEN cDNA 3300001H21 gene
106
2.3
NM_027334


4631422C05Rik
RIKEN cDNA 4631422C05 gene
716
1.9
BI648645


4930513H15Rik
RIKEN cDNA 4930513H15 gene
49
2.4
AK017117


4931406H21Rik
RIKEN cDNA 4931406H21 gene
75
2.0
BG076071


4931408A02Rik
RIKEN cDNA 4931408A02 gene
58
3.7
AK016443


4933402B14Rik
RIKEN cDNA 4933402B14 gene
45
2.2
AV278444


5430425C04Rik
RIKEN cDNA 5430425C04 gene
44
2.9
AK017334


5830458K16Rik
RIKEN cDNA 5830458K16 gene
525
2.6
BC024872


6330407A03Rik
RIKEN cDNA 6330407A03 gene
60
2.2
AW519657


6720477E09Rik
RIKEN cDNA 6720477E09 gene
132
2.3
BB053506


9230117N10Rik
RIKEN cDNA 9230117N10 gene
222
2.2
NM_133775


9330174J19Rik
RIKEN cDNA 9330174J19 gene
39
4.4
BE687891


A330021E22Rik
RIKEN cDNA A330021E22 gene
52
2.0
BB561281


A830021K08Rik
RIKEN cDNA A830021K08 gene
825
2.4
BB291885


A930021H16Rik
RIKEN cDNA A930021H16 gene
54
2.1
BB513585


B830010L13Rik
RIKEN cDNA B830010L13 gene
144
2.6
BB333374


C330012H03Rik
RIKEN cDNA C330012H03 gene
69
2.0
BB098431


D430019H16Rik
RIKEN cDNA D430019H16 gene
57
2.5
BM116882


D730043B02Rik
RIKEN cDNA D730043B02 gene
104
2.2
AK021336


E530005C20Rik
RIKEN cDNA E530005C20 gene
56
2.0
BB662566


Robo2
roundabout homolog 2 (Drosophila)
22
2.3
BB366379


Sall1
sal-like 1 (Drosophila)
687
2.1
BB739342


Sema3e
sema domain, immunoglobulin domain
60
2.0
NM_011348



(Ig), short basic domain, secreted,



(semaphorin) 3E


Serpina10
serine (or cysteine) proteinase inhibitor,
211
7.6
BC018416



clade A (alpha-1 antiproteinase,



antitrypsin), member 10


Serpina3g
serine (or cysteine) proteinase inhibitor,
92
4.5
BC002065



clade A, member 3G


Serpinb9
serine (or cysteine) proteinase inhibitor,
323
2.1
BE686716



clade B, member 9


Serping1
serine (or cysteine) proteinase inhibitor,
2372
3.8
NM_009776



clade G, member 1


Stard13
serologically defined colon cancer antigen
151
2.0
BB667840



13


Stat1
signal transducer and activator of
171
3.8
AW214029



transcription 1


Stat1
signal transducer and activator of
915
2.7
AW214029



transcription 1


Stat1
signal transducer and activator of
808
2.8
AW214029



transcription 1


Slamf8
SLAM family member 8
27
3.3
BC024587


Slc7a12
solute carrier family 7 (cationic amino acid
290
29.4
NM_080852



transporter, y+ system), member 12


Slco2a1
solute carrier organic anion transporter
349
2.1
NM_033314



family, member 2a1


Stab2
stabilin 2
230
1.9
NM_138673


Scd1
stearoyl-Coenzyme A desaturase 1
2255
5.6
NM_009127


Scd1
stearoyl-Coenzyme A desaturase 1
389
3.5
NM_009127


Socs2
suppressor of cytokine signaling 2
478
3.7
NM_007706


Socs2
suppressor of cytokine signaling 2
354
4.7
NM_007706


Syt13
synaptotagmin 13
37
3.3
BB244585


Tapbp
TAP binding protein
2304
3.5
AF043943


Tbx3
T-box 3
58
2.1
BB728182


Tgtp
T-cell specific GTPase
1220
8.9
NM_011579


Thoc1
THO complex 1
33
2.2
BB647938


Thbs1
thrombospondin 1
727
2.1
AI385532


Tmsb10
thymosin, beta 10
941
2.4
NM_025284


Top2a
topoisomerase (DNA) II alpha
142
2.0
BM211413


Tle2
transducin-like enhancer of split 2,
150
2.1
AU067681



homolog of Drosophila E(spl)


Tgfbi
transforming growth factor, beta induced
294
2.3
NM_009369


Tgfbi
transforming growth factor, beta induced
229
2.5
NM_009369


Tm4sf3
transmembrane 4 superfamily member 3
124
2.1
C76990


Tap1
transporter 1, ATP-binding cassette, sub-
127
5.7
AW048052



family B (MDR/TAP)


Tmlhe
trimethyllysine hydroxylase, epsilon
66
1.9
BC005497


Tpm2
tropomyosin 2, beta
307
2.1
BC024358


Tubb2
tubulin, beta 2
969
2.3
BC003475


Tnfsf13b
tumor necrosis factor (ligand) superfamily,
101
2.4
NM_033622



member 13b


Arts1
type 1 tumor necrosis factor receptor
444
2.3
NM_030711



shedding aminopeptidase regulator


Arts1
type 1 tumor necrosis factor receptor
221
2.8
AV287655



shedding aminopeptidase regulator


Ubd
ubiquitin D
121
11.5
NM_023137


Utx
ubiquitously transcribed tetratricopeptide
22
2.6
BB306686



repeat gene, X chromosome


Vcam1
vascular cell adhesion molecule 1
268
2.6
BB250384


Was
Wiskott-Aldrich syndrome homolog
25
3.8
NM_009515



(human)


Xdh
xanthine dehydrogenase
167
4.7
AV286265


Zbp1
Z-DNA binding protein 1
49
5.1
AK008179


Zdhhc6
zinc finger, DHHC domain containing 6
70
2.0
BB251023
















TABLE 2







Rejection-induced transcripts (RITs)
















WT D5



Gene Symbol


NCBA
vs


Affymetrix
Common
Gene Title Affymetrix
Raw
NCBA
Genbank















0610009C03Rik
0610009C03Rik
RIKEN cDNA 0610009C03 gene
538
2.0
AK002371


0610025L06Rik
0610025L06Rik
RIKEN cDNA 0610025L06 gene
277
5.2
AK012581


0610033I05Rik
0610033I05Rik
RIKEN cDNA 0610033I05 gene
407
3.0
BC003333


0610037M15Rik
0610037M15Rik
RIKEN cDNA 0610037M15 gene
169
15.6
BG916808


0610039P13Rik
0610039P13Rik
RIKEN cDNA 0610039P13 gene
141
3.4
BC021548


—
0910001A06Rik

Mus musculus 3 days neonate thymus
60
4.2
BB229269




cDNA, RIKEN full-length enriched library,




clone: A630020J17 product: unknown




EST, full insert sequence


0910001A06Rik
0910001A06Rik
RIKEN cDNA 0910001A06 gene
663
6.7
BC011343


0910001A06Rik
0910001A06Rik
RIKEN cDNA 0910001A06 gene
63
2.3
AV033641


1100001H23Rik
1100001H23Rik
RIKEN cDNA 1100001H23 gene
988
4.4
NM_025806


1100001I19Rik
1100001I19Rik
RIKEN cDNA 1100001I19 gene
288
2.1
BM119324


1100001I19Rik
1100001I19Rik
RIKEN cDNA 1100001I19 gene
219
2.8
BE949451


1110006O17Rik
1110006O17Rik
RIKEN cDNA 1110006O17 gene
199
5.1
BB736636


1110007F12Rik
1110007F12Rik
RIKEN cDNA 1110007F12 gene
30
4.0
BB765808


1110007F12Rik
1110007F12Rik
RIKEN cDNA 1110007F12 gene
1154
3.0
BC020080


—
1110007H17Rik

Mus musculus 0 day neonate lung cDNA,
97
2.1
BI466783




RIKEN full-length enriched library,




clone: E030022F06 product: inferred:




exchange factor for ARF6 {Rattus





norvegicus}, full insert sequence


1110008F13Rik
1110008F13Rik
RIKEN cDNA 1110008F13 gene
16
6.7
AV316605


1110013L07Rik
1110013L07Rik
RIKEN cDNA 1110013L07 gene
165
3.0
BB765852


—
1110033M05Rik

Mus musculus transcribed sequences
34
2.1
BM220862


1200002N14Rik
1200002N14Rik
RIKEN cDNA 1200002N14 gene
470
4.3
BC021433


1200008O12Rik
1200008O12Rik
RIKEN cDNA 1200008O12 gene
44
16.3
AK004655


1200009I06Rik
1200009I06Rik
RIKEN cDNA 1200009I06 gene
270
2.0
AK005443


1200013B08Rik
1200013B08Rik
RIKEN cDNA 1200013B08 gene
183
8.3
AK004734


1300002K09Rik
1300002K09Rik
RIKEN cDNA 1300002K09 gene
141
3.6
AV222559


1500001L15Rik
1500001L15Rik
RIKEN cDNA 1500001L15 gene
921
2.1
BB559925


1500002B03Rik
1500002B03Rik
RIKEN cDNA 1500002B03 gene
175
2.4
AK005105


1500004A08Rik
1500004A08Rik
RIKEN cDNA 1500004A08 gene
219
2.3
BB030508


1500031M22Rik
1500031M22Rik
RIKEN cDNA 1500031M22 gene
119
2.1
AK015145


1700013H19Rik
1700013H19Rik
RIKEN cDNA 1700013H19 gene
144
2.3
AK005954


1700022C02Rik
1700022C02Rik
RIKEN cDNA 1700022C02 gene
24
3.9
AK014919


1700025G04Rik
1700025G04Rik
RIKEN cDNA 1700025G04 gene
110
2.0
AW557527


1700001M19Rik
1700029K01Rik
RIKEN cDNA 1700001M19 gene
59
2.0
BG075808


1700047I17Rik
1700047I17Rik
RIKEN cDNA 1700047I17 gene
65
3.8
BB824055


1700061I17Rik
1700061I17Rik
RIKEN cDNA 1700061I17 gene
27
2.5
AK006854


—
1700091G21Rik

Mus musculus 16 days neonate thymus
97
4.3
BG075562




cDNA, RIKEN full-length enriched library,




clone: A130042K22 product: unknown




EST, full insert sequence


1700095N21Rik
1700095N21Rik
RIKEN cDNA 1700095N21 gene
151
2.3
NM_029682


—
1700097N02Rik

Mus musculus adult male testis cDNA,
16
5.0
AA266367




RIKEN full-length enriched library,




clone: 1700122G02 product: unknown




EST, full insert sequence


1810019A08Rik
1810019A08Rik
RIKEN cDNA 1810019A08 gene
80
5.1
AK007540


1810033B17Rik
1810033B17Rik
RIKEN cDNA 1810033B17 gene
38
6.4
BB533148


1810037B05Rik
1810037B05Rik
RIKEN cDNA 1810037B05 gene
50
3.1
AK007714


1810049K24Rik
1810049K24Rik
RIKEN cDNA 1810049K24 gene
484
2.4
BB558800


1810054D07Rik
1810054D07Rik
RIKEN cDNA 1810054D07 gene
40
5.0
AK007856


1810054D07Rik
1810054D07Rik
RIKEN cDNA 1810054D07 gene
45
5.4
BB397062


1810054D07Rik
1810054D07Rik
RIKEN cDNA 1810054D07 gene
99
4.5
BB259628


—
1810057P16Rik

Mus musculus 10 days neonate cortex
94
2.6
BB275943




cDNA, RIKEN full-length enriched library,




clone: A830095F23 product: unknown




EST, full insert sequence


1810062O14Rik
1810062O14Rik
RIKEN cDNA 1810062O14 gene
99
7.4
AV060417


2010012C16Rik
2010012C16Rik
RIKEN cDNA 2010012C16 gene
187
3.0
AK006303


—
2010012F05Rik

Mus musculus adult male colon cDNA,
54
2.2
AK018542




RIKEN full-length enriched library,




clone: 9030607L20 product: weakly similar




to MHC CLASS I T7 ANTIGEN




(FRAGMENT) [Mus musculus], full insert




sequence


2010106G01Rik
2010106G01Rik
RIKEN cDNA 2010106G01 gene
1397
2.0
NM_023220


2010109K11Rik
2010109K11Rik
RIKEN cDNA 2010109K11 gene
256
3.2
BB174749


2010308M01Rik
2010308M01Rik
RIKEN cDNA 2010308M01 gene
163
2.3
BC008266


A430106J12Rik
2010316F05Rik
RIKEN cDNA A430106J12 gene
41
3.5
BB228331


2200002D01Rik
2200002D01Rik
RIKEN cDNA 2200002D01 gene
189
2.3
AK008617


2210421G13Rik
2210421G13Rik
RIKEN cDNA 2210421G13 gene
19
9.3
AV081797


2310014H01Rik
2310014H01Rik
RIKEN cDNA 2310014H01 gene
331
3.3
AK009340


2310015N21Rik
2310015N21Rik
RIKEN cDNA 2310015N21 gene
300
2.9
AK009372


2310031L18Rik
2310031L18Rik
RIKEN cDNA 2310031L18 gene
76
3.4
BC027435


2310032F03Rik
2310032F03Rik
RIKEN cDNA 2310032F03 gene
36
7.7
BE633038


2310043D08Rik
2310043D08Rik
RIKEN cDNA 2310043D08 gene
28
5.6
BF021255


—
2310047A01Rik

Mus musculus similar to hypothetical
81
2.0
BB813478




protein FLJ90798 (LOC382857), mRNA


2310047O13Rik
2310047O13Rik
RIKEN cDNA 2310047O13 gene
18
2.9
AW554864


2310061F22Rik
2310061F22Rik
RIKEN cDNA 2310061F22 gene
734
2.1
BB253397


2310067E08Rik
2310067E08Rik
RIKEN cDNA 2310067E08 gene
246
2.5
BF168366


2310075C12Rik
2310075C12Rik
RIKEN cDNA 2310075C12 gene
850
2.2
NM_133739


2400006A19Rik
2400006A19Rik
RIKEN cDNA 2400006A19 gene
288
7.5
BC006869


2410002M20Rik
2410002M20Rik
RIKEN cDNA 2410002M20 gene
637
2.2
BM209793


2410002O22Rik
2410002O22Rik
RIKEN cDNA 2410002O22 gene
48
2.4
AK012141


2410004I17Rik
2410004I17Rik
RIKEN cDNA 2410004I17 gene
26
6.8
AK010391


—
2410006H16Rik

Mus musculus ES cells cDNA, RIKEN
359
2.3
AA939619




full-length enriched library,




clone: 2410006H16 product: unknown




EST, full insert sequence


2410012M04Rik
2410012M04Rik
RIKEN cDNA 2410012M04 gene
58
2.0
BG229936


B230342M21Rik
2410024N18Rik
RIKEN cDNA B230342M21 gene
40
3.2
AK010587


2410030K01Rik
2410030K01Rik
RIKEN cDNA 2410030K01 gene
130
2.4
BF577722


—
2410129E14Rik

Mus musculus transcribed sequence with
374
3.2
AA986082




strong similarity to protein




ref: NP_001060.1 (H. sapiens) tubulin,




beta polypeptide [Homo sapiens]


2600005O03Rik
2600005O03Rik
RIKEN cDNA 2600005O03 gene
22
5.5
AK011162


—
2610002F03Rik

Mus musculus ES cells cDNA, RIKEN
24
3.7
AV011566




full-length enriched library,




clone: 2410046H18 product: unknown




EST, full insert sequence


2610028H07Rik
2610028H07Rik
RIKEN cDNA 2610028H07 gene
365
2.9
BC006738


2610029G23Rik
2610029G23Rik
RIKEN cDNA 2610029G23 gene
582
2.0
NM_026312


—
2610036L11Rik

Mus musculus adult male testis cDNA,
68
3.7
BF453953




RIKEN full-length enriched library,




clone: 1700015C21 product: unknown




EST, full insert sequence


2610039C10Rik
2610039C10Rik
RIKEN cDNA 2610039C10 gene
153
3.9
AK012533


2610040C18Rik
2610040C18Rik
RIKEN cDNA 2610040C18 gene
25
4.3
AU043467


2610042L04Rik
2610042L04Rik
RIKEN cDNA 2610042L04 gene
203
5.0
BM195235


2610042L04Rik
2610042L04Rik
RIKEN cDNA 2610042L04 gene
337
4.9
BM195235


2610206B13Rik
2610206B13Rik
RIKEN cDNA 2610206B13 gene
105
2.6
AK011896


2610208M17Rik
2610208M17Rik
RIKEN cDNA 2610208M17 gene
227
2.8
BI104583


2610208M17Rik
2610208M17Rik
RIKEN cDNA 2610208M17 gene
610
3.5
BI104583


2610208M17Rik
2610208M17Rik
RIKEN cDNA 2610208M17 gene
114
3.1
BQ129438


2610300B10Rik
2610300B10Rik
RIKEN cDNA 2610300B10 gene
87
2.6
BB538449


—
2610307O08Rik
—
47
18.7
AV300716


2610307O08Rik
2610307O08Rik
RIKEN cDNA 2610307O08 gene
246
6.8
AK012006


—
2610318C08Rik

Mus musculus adult male small intestine
156
2.5
AA197362




cDNA, RIKEN full-length enriched library,




clone: 2010016H04 product: unknown




EST, full insert sequence


2610318N02Rik
2610318N02Rik
RIKEN cDNA 2610318N02 gene
21
7.0
AK012048


2610510H01Rik
2610510H01Rik
RIKEN cDNA 2610510H01 gene
214
2.1
AV122997


2610510H01Rik
2610510H01Rik
RIKEN cDNA 2610510H01 gene
253
2.4
AV122997


2610510J17Rik
2610510J17Rik
RIKEN cDNA 2610510J17 gene
155
3.0
BM230253


2700019D07Rik
2700019D07Rik
RIKEN cDNA 2700019D07 gene
369
2.7
BM937429


—
2700038G22Rik

Mus musculus adult retina cDNA, RIKEN
141
2.3
AK012332




full-length enriched library,




clone: A930033E24




product: unclassifiable, full insert




sequence


2700049P18Rik
2700049P18Rik
RIKEN cDNA 2700049P18 gene
73
2.4
AV127670


2810026P18Rik
2810026P18Rik
RIKEN cDNA 2810026P18 gene
209
3.1
AK012825


2810047L02Rik
2810047L02Rik
RIKEN cDNA 2810047L02 gene
19
8.8
AV270035


2810052M02Rik
2810052M02Rik
RIKEN cDNA 2810052M02 gene
99
4.6
NM_023320


2810406C15Rik
2810406C15Rik
RIKEN cDNA 2810406C15 gene
103
5.4
BC025460


2810417H13Rik
2810417H13Rik
RIKEN cDNA 2810417H13 gene
165
23.4
AK017673


2810417H13Rik
2810417H13Rik
RIKEN cDNA 2810417H13 gene
44
17.7
AK017673


2810418N01Rik
2810418N01Rik
RIKEN cDNA 2810418N01 gene
115
3.2
AK013116


A330067P21
2810453L12Rik
hypothetical protein A330067P21
65
2.2
BG085812


2810457I06Rik
2810457I06Rik
RIKEN cDNA 2810457I06 gene
186
2.6
AK013361


2810457I06Rik
2810457I06Rik
RIKEN cDNA 2810457I06 gene
180
3.0
AW045947


6720435I21Rik
2810474O19Rik
RIKEN cDNA 6720435I21 gene
860
2.2
AA509870


2900024D24Rik
2900024D24Rik
RIKEN cDNA 2900024D24 gene
48
10.4
BB134696


2900024D24Rik
2900024D24Rik
RIKEN cDNA 2900024D24 gene
82
4.3
AI449126


Krc
2900056N03Rik
kappa B and Rss recognition component
88
5.0
BB164127


3110010F15Rik
3110010F15Rik
RIKEN cDNA 3110010F15 gene
173
2.6
BF320755


3110010F15Rik
3110010F15Rik
RIKEN cDNA 3110010F15 gene
307
2.0
BF320755


3110037K17Rik
3110037K17Rik
RIKEN cDNA 3110037K17 gene
58
21.7
AK014135


3300001P08Rik
3300001P08Rik
RIKEN cDNA 3300001P08 gene
64
2.4
BM213851


4432406C08Rik
4432406C08Rik
RIKEN cDNA 4432406C08 gene
16
10.0
BM247465


4631422C13Rik
4631422C13Rik
RIKEN cDNA 4631422C13 gene
27
2.8
BB154962


AW413625
4632417K18Rik
expressed sequence AW413625
80
15.2
NM_026640


4632428N05Rik
4632428N05Rik
RIKEN cDNA 4632428N05 gene
139
2.6
BC003967


4632434I11Rik
4632434I11Rik
RIKEN cDNA 4632434I11 gene
20
2.8
BB463610


4732429D16Rik
4732429D16Rik
RIKEN cDNA 4732429D16 gene
130
2.0
BC019814


4732490P18Rik
4732490P18Rik
RIKEN cDNA 4732490P18 gene
31
2.1
BB009703


—
4833403J16Rik

Mus musculus 0 day neonate head
41
2.5
AK014653




cDNA, RIKEN full-length enriched library,




clone: 4833403J16 product: unknown




EST, full insert sequence


4833427B12Rik
4833427B12Rik
RIKEN cDNA 4833427B12 gene
24
7.7
AW488914


4921501M20Rik
4921501M20Rik
RIKEN cDNA 4921501M20 gene
46
3.5
AF361364


—
4921511E18Rik

Mus musculus adult male testis cDNA,
107
2.2
AK014868




RIKEN full-length enriched library,




clone: 4921511E18




product: unclassifiable, full insert




sequence


4930427A07Rik
4930427A07Rik
RIKEN cDNA 4930427A07 gene
58
2.9
BE951637


4930477M19
4930477M19
hypothetical protein 4930477M19
66
2.4
BB017021


4930503L19Rik
4930503L19Rik
RIKEN cDNA 4930503L19 gene
42
3.5
AI450962


4930503L19Rik
4930503L19Rik
RIKEN cDNA 4930503L19 gene
27
6.4
AI450962


4930547N16Rik
4930547N16Rik
RIKEN cDNA 4930547N16 gene
10
6.9
BM205349


4930547N16Rik
4930547N16Rik
RIKEN cDNA 4930547N16 gene
25
3.5
BM877490


4930553M18Rik
4930553M18Rik
RIKEN cDNA 4930553M18 gene
83
2.1
BG065617


—
4930571N24Rik

Mus musculus transcribed sequence with
20
3.5
BE687174




moderate similarity to protein sp: P00722




(E. coli) BGAL_ECOLI Beta-




galactosidase (Lactase)


4930579G24Rik
4930579G24Rik
RIKEN cDNA 4930579G24 gene
99
3.0
BB821996


4931400A14Rik
4931400A14Rik
RIKEN cDNA 4931400A14 gene
533
2.8
AK016419


—
4933412E12Rik

Mus musculus 13 days embryo heart
197
2.2
AK016788




cDNA, RIKEN full-length enriched library,




clone: D330011B05 product: unknown




EST, full insert sequence


4933426L22Rik
4933426L22Rik
RIKEN cDNA 4933426L22 gene
88
3.8
BB361436


4933426L22Rik
4933426L22Rik
RIKEN cDNA 4933426L22 gene
40
5.6
BB667247


4933430F08Rik
4933430F08Rik
RIKEN cDNA 4933430F08 gene
31
37.4
AK016990


4933431N12Rik
4933431N12Rik
RIKEN cDNA 4933431N12 gene
38
4.1
BE853276


5033406L14Rik
5033406L14Rik
RIKEN cDNA 5033406L14 gene
101
3.1
BB667600


—
5033413D16Rik

Mus musculus 0 day neonate eyeball
144
2.4
AK017164




cDNA, RIKEN full-length enriched library,




clone: E130011D04 product: unknown




EST, full insert sequence


—
5230400M03Rik

Mus musculus adult male xiphoid
57
2.9
BB312292




cartilage cDNA, RIKEN full-length




enriched library, clone: 5230400M03




product: unclassifiable, full insert




sequence


A630029F06
5330417K06Rik
hypothetical protein A630029F06
182
3.0
BB023868


5430427O19Rik
5430427O19Rik
RIKEN cDNA 5430427O19 gene
23
7.3
AI645098


5430435G22Rik
5430435G22Rik
RIKEN cDNA 5430435G22 gene
53
7.4
BB128517


—
5430437J10Rik

Mus musculus, clone IMAGE: 5356629,
12
4.9
BF227338




mRNA


—
5730405O12Rik

Mus musculus 0 day neonate eyeball
19
3.1
AK017499




cDNA, RIKEN full-length enriched library,




clone: E130007N07




product: unclassifiable, full insert




sequence


5730466H23Rik
5730466H23Rik
RIKEN cDNA 5730466H23 gene
26
2.1
BB079695


—
5730507H05Rik

Mus musculus adult male hypothalamus
25
10.1
BB702347




cDNA, RIKEN full-length enriched library,




clone: A230105F24 product: hypothetical




protein, full insert sequence


5730508B09Rik
5730508B09Rik
RIKEN cDNA 5730508B09 gene
179
3.5
AK017758


5730508B09Rik
5730508B09Rik
RIKEN cDNA 5730508B09 gene
47
11.2
C80506


—
5730601F06Rik

Mus musculus 16 days embryo head
71
2.2
BB374879




cDNA, RIKEN full-length enriched library,




clone: C130077H22




product: unclassifiable, full insert




sequence


5830405N20Rik
5830405N20Rik
RIKEN cDNA 5830405N20 gene
49
2.5
BB202848


5830405N20Rik
5830405N20Rik
RIKEN cDNA 5830405N20 gene
19
5.9
AK017900


9630005B12Rik
5830411O09Rik
RIKEN cDNA 9630005B12 gene
139
2.4
BB431654


9630005812Rik
5830411O09Rik
RIKEN cDNA 9630005B12 gene
114
2.7
BB431654


5830426I05Rik
5830426I05Rik
RIKEN cDNA 5830426I05 gene
102
6.9
NM_133762


AI595338
5830443L24Rik
expressed sequence AI595338
174
75.0
NM_029509


5830458K16Rik
5830458K16Rik
RIKEN cDNA 5830458K16 gene
23
4.8
BC024872


5830458K16Rik
5830458K16Rik
RIKEN cDNA 5830458K16 gene
525
9.1
BC024872


5830482F20Rik
5830482F20Rik
RIKEN cDNA 5830482F20 gene
122
3.6
AW493583


5830484A20Rik
5830484A20Rik
RIKEN cDNA 5830484A20 gene
99
4.8
AW909306


—
6030405P05Rik

Mus musculus 13 days embryo male
125
7.5
BM244999




testis cDNA, RIKEN full-length enriched




library, clone: 6030405P05




product: unclassifiable, full insert




sequence


6030423D04Rik
6030423D04Rik
RIKEN cDNA 6030423D04 gene
48
6.1
BE986588


6230416J20Rik
6230416J20Rik
RIKEN cDNA 6230416J20 gene
37
2.2
BB794620


6330406L22Rik
6330406L22Rik
RIKEN cDNA 6330406L22 gene
56
7.7
AK018130


6330407A03Rik
6330407A03Rik
RIKEN cDNA 6330407A03 gene
60
3.3
AW519657


6330412F12Rik
6330412F12Rik
RIKEN cDNA 6330412F12 gene
303
2.0
BG066220


6330442E10Rik
6330442E10Rik
RIKEN cDNA 6330442E10 gene
22
7.5
AV328515


—
6330442E10Rik
—
82
4.2
BB302103


6330500D04Rik
6330500D04Rik
RIKEN cDNA 6330500D04 gene
87
2.8
BB867666


6330500D04Rik
6330500D04Rik
RIKEN cDNA 6330500D04 gene
104
3.9
BM242294


6330500D04Rik
6330500D04Rik
RIKEN cDNA 6330500D04 gene
66
2.3
AV329070


6330503K22Rik
6330503K22Rik
RIKEN cDNA 6330503K22 gene
182
2.3
BG070835


6330583I20Rik
6330583I20Rik
RIKEN cDNA 6330583I20 gene
43
2.5
BM248637


—
6430570G24

Mus musculus adult male olfactory brain
241
3.1
BG069663




cDNA, RIKEN full-length enriched library,




clone: 6430570G24 product: unknown




EST, full insert sequence


—
6430570G24

Mus musculus adult male olfactory brain
606
3.8
BG069663




cDNA, RIKEN full-length enriched library,




clone: 6430570G24 product: unknown




EST, full insert sequence


MGC66590
6430706D22Rik
Unknown (protein for MGC: 66590)
24
2.3
BC004768


MGC66590
6430706D22Rik
Unknown (protein for MGC: 66590)
271
2.3
BM248225


6530401D17Rik
6530401D17Rik
RIKEN cDNA 6530401D17 gene
34
2.7
AK013740


6820428D13
6820428D13
hypothetical protein 6820428D13
39
2.7
BG064903


—
8030448K23Rik

Mus musculus transcribed sequences
98
2.1
BM204579


8430437G11Rik
8430437G11Rik
RIKEN cDNA 8430437G11 gene
271
2.2
BC007160


9030408N13Rik
9030408N13Rik
RIKEN cDNA 9030408N13 gene
66
7.0
NM_025779


9030625A04Rik
9030625A04Rik
RIKEN cDNA 9030625A04 gene
217
2.0
AV373606


9130002C22Rik
9130002C22Rik
RIKEN cDNA 9130002C22 gene
476
24.4
BM243571


9130017N09Rik
9130017N09Rik
RIKEN cDNA 9130017N09 gene
339
2.5
BQ030875


9130019I15Rik
9130019I15Rik
RIKEN cDNA 9130019I15 gene
16
46.3
AK018636


9130022K13Rik
9130022K13Rik
RIKEN cDNA 9130022K13 gene
65
5.6
AK018646


—
9130211I03Rik

Mus musculus similar to Jun dimerization
64
4.9
AK020278




protein 1 gene (LOC381319), mRNA


9130422G05Rik
9130422G05Rik
RIKEN cDNA 9130422G05 gene
177
5.0
AK018685


9130422G05Rik
9130422G05Rik
RIKEN cDNA 9130422G05 gene
195
4.4
AK018685


9230105E10Rik
9230105E10Rik
RIKEN cDNA 9230105E10 gene
108
3.6
BB433710


—
9230110J10

Mus musculus transcribed sequences
58
4.4
BG967674


9230117N10Rik
9230117N10Rik
RIKEN cDNA 9230117N10 gene
222
7.6
NM_133775


9330132E09Rik
9330132E09Rik
RIKEN cDNA 9330132E09 gene
189
2.3
AV336691


9330175E14Rik
9330175E14Rik
RIKEN cDNA 9330175E14 gene
11
8.0
BB082472


MGC6357
9430034N14Rik
hypothetical protein MGC6357
68
2.2
BB667558


—
9430065F17Rik

Mus musculus 12 days embryo
30
2.1
AK021377




embryonic body between diaphragm




region and neck cDNA, RIKEN full-length




enriched library, clone: 9430065F17




product: unclassifiable, full insert




sequence


9430077D24Rik
9430077D24Rik
RIKEN cDNA 9430077D24 gene
559
2.0
BG865652


—
9530028C05

Mus musculus adult male testis cDNA,
278
3.9
BQ175154




RIKEN full-length enriched library,




clone: 4921508F21 product: similar to




HISTOCOMPATIBILITY 2, CLASS II




ANTIGEN E BETA [Mus musculus], full




insert sequence


—
9530028C05

Mus musculus adult male testis cDNA,
228
4.6
BQ175154




RIKEN full-length enriched library,




clone: 4921508F21 product: similar to




HISTOCOMPATIBILITY 2, CLASS II




ANTIGEN E BETA [Mus musculus], full




insert sequence


—
9530053H05Rik
—
108
4.5
AK020608


9630044O09Rik
9630044O09Rik
RIKEN cDNA 9630044O09 gene
71
3.0
BB704967


AI645720
9630054F20Rik
expressed sequence AI645720
106
2.1
BB131620


—
9630055N22Rik

Mus musculus adult retina cDNA, RIKEN
523
1.9
BB276950




full-length enriched library,




clone: A930001C09 product: TAIL




FIBROBLAST RECEPTOR FOR FELINE




LEUKEMIA VIRUS SUBGROUP C




homolog [Mus dunni], full insert sequence


9830147J24Rik
9830147J24Rik
RIKEN cDNA 9830147J24 gene
83
38.2
BC010229


—
A130052D22

Mus musculus transcribed sequence with
448
2.1
BB194075




strong similarity to protein




ref: NP_057365.1 (H. sapiens) STE20-like




kinase; STE2-like kinase [Homo sapiens]


A130092J06Rik
A130092J06Rik
RIKEN cDNA A130092J06 gene
141
3.6
BI111848


A130096K20
A130096K20
hypothetical protein A130096K20
576
2.5
AV256780


—
A230061C15Rik

Mus musculus adult male hypothalamus
112
3.2
BB153043




cDNA, RIKEN full-length enriched library,




clone: A230061C15 product: unknown




EST, full insert sequence


A330021E22Rik
A330021E22Rik
RIKEN cDNA A330021E22 gene
52
2.2
BB561281


A330042H22
A330042H22
hypothetical protein A330042H22
87
11.3
AW743924


—
A330042I21Rik

Mus musculus adult male spinal cord
1523
3.6
AI645293




cDNA, RIKEN full-length enriched library,




clone: A330042I21 product: unknown EST,




full insert sequence


A330102K04
A330102K04Rik
hypothetical protein A330102K04
35
5.5
AA214835


—
A430093F15Rik

Mus musculus 0 day neonate thymus
54
4.9
BB209605




cDNA, RIKEN full-length enriched library,




clone: A430093F15 product: hypothetical




protein, full insert sequence


A430106J12Rik
A430106J12Rik
RIKEN cDNA A430106J12 gene
140
2.1
BB498608


A430107D22Rik
A430107D22Rik
RIKEN cDNA A430107D22 gene
68
4.8
AI481597


A430107D22Rik
A430107D22Rik
RIKEN cDNA A430107D22 gene
26
16.4
AV312663


—
A530052I06Rik

Mus musculus adult male aorta and vein
14
3.3
BM239855




cDNA, RIKEN full-length enriched library,




clone: A530052I06 product: unknown EST,




full insert sequence


A630077B13Rik
A630077B13Rik
RIKEN cDNA A630077B13 gene
5
183.1
BB239429


Znfn1a2
A730095J18Rik
zinc finger protein, subfamily 1A, 2
59
3.6
BB291816




(Helios)


Znfn1a2
A730095J18Rik
zinc finger protein, subfamily 1A, 2
273
2.4
BB319935




(Helios)


—
AA536717

Mus musculus 3 days neonate thymus
31
3.2
BB201845




cDNA, RIKEN full-length enriched library,




clone: A630021I17 product: unknown EST,




full insert sequence


AA536743
AA536743
expressed sequence AA536743
368
2.6
BI248354


AA536743
AA536743
expressed sequence AA536743
543
3.0
BI248354


AA589481
AA589481
expressed sequence AA589481
123
2.1
BB826899


—
AB124611

Mus musculus 13 days embryo male
65
10.6
BM246462




testis cDNA, RIKEN full-length enriched




library, clone: 6030438F01




product: unclassifiable, full insert




sequence


Abp1
Abp1
amiloride binding protein 1 (amine
188
8.7
BC021880




oxidase, copper-containing)


Facl4
Acsl4
fatty acid-Coenzyme A ligase, long chain 4
174
2.2
AB033886


Facl5
Acsl5; ACS2;
fatty acid Coenzyme A ligase, long chain 5
2295
2.1
AK006541



ACS5; Facl5;



1700030F05Rik


Strm
Actn1
striamin
153
2.0
BC003232


Actr3
Actr3
ARP3 actin-related protein 3 homolog
4339
2.2
BE372352




(yeast)


Actr3
Actr3
ARP3 actin-related protein 3 homolog
3734
2.2
BE372352




(yeast)


Adam12
Adam12
a disintegrin and metalloproteinase
141
2.4
NM_007400




domain 12 (meltrin alpha)


Adam8
Adam8
a disintegrin and metalloprotease domain 8
54
4.4
NM_007403


Adamts1
Adamts1
a disintegrin-like and metalloprotease
863
4.5
D67076




(reprolysin type) with thrombospondin




type 1 motif, 1


Adamts2
Adamts2
a disintegrin-like and metalloprotease
139
2.3
BM125019




(reprolysin type) with thrombospondin




type 1 motif, 2


Adamts4
Adamts4
a disintegrin-like and metalloprotease
60
5.6
BB443585




(reprolysin type) with thrombospondin




type 1 motif, 4


Adamts6
Adamts6
a disintegrin-like and metalloprotease
22
3.0
BB227648




(reprolysin type) with thrombospondin




type 1 motif, 6


—
Adar

Mus musculus transcribed sequence with
103
3.5
BB308291




weak similarity to protein




ref: NP_081764.1 (M. musculus) RIKEN




cDNA 5730493B19 [Mus musculus]


Adcy7
Adcy7
adenylate cyclase 7
118
17.3
BB746807


Adfp
Adfp
adipose differentiation related protein
1090
2.7
NM_007408


Adrbk1
Adrbk1
adrenergic receptor kinase, beta 1
490
2.1
AF333028


4833444A01Rik
Adrbk2
RIKEN cDNA 4833444A01 gene
235
2.0
BG073639


Agpat4
Agpat4
1-acylglycerol-3-phosphate O-
241
2.5
BE994529




acyltransferase 1 (lysophosphatidic acid




acyltransferase, delta)


AI114950
AI114950
expressed sequence AI114950
244
2.7
BB224153


—
AI132321

Mus musculus transcribed sequence with
44
27.8
BB210623




weak similarity to protein




ref: NP_036400.1 (H. sapiens) similar to




vaccinia virus HindIII K4L ORF [Homo





sapiens]


AI854251
AI413582
expressed sequence AI854251
116
2.4
AV039444


—
AI426953

Mus musculus 2 days neonate thymus
38
2.4
BE632903




thymic cells cDNA, RIKEN full-length




enriched library, clone: E430023L24




product: unknown EST, full insert




sequence


—
AI447881

Mus musculus transcribed sequences
102
2.7
AI447881


AI447904
AI447904
expressed sequence AI447904
59
26.2
BM241008


AI447904
AI447904
expressed sequence AI447904
7
70.3
BM241008


—
AI449310

Mus musculus transcribed sequences
72
2.4
AW552116


AI449441
AI449441
expressed sequence AI449441
91
2.5
AV094878


—
AI451557

Mus musculus transcribed sequences
87
24.1
AV277444


AI452102
AI452102
expressed sequence AI452102
45
3.3
BB312740


AI467606
AI467606
expressed sequence AI467606
168
10.2
BB234337


AI467606
AI467606
expressed sequence AI467606
25
9.5
BB234337


—
AI504062

Mus musculus 9 days embryo whole
415
2.7
BM238926




body cDNA, RIKEN full-length enriched




library, clone: D030050E20




product: unclassifiable, full insert




sequence


AI504432
AI504432
expressed sequence AI504432
30
15.1
BB202185


Kcna3
AI504432
potassium voltage-gated channel,
23
18.8
AI323624




shaker-related subfamily, member 3


AI597013
AI597013
expressed sequence AI597013
47
6.1
BB014626


AI597013
AI597013
expressed sequence AI597013
77
7.9
BB014626


LOC226691
AI607873
interferon-activatable protein
15
28.9
AI607873


AI661017
AI661017
expressed sequence AI661017
21
15.4
AV173260


—
AI661384

Mus musculus transcribed sequences
11
14.9
BB034038


—
AI848100

Mus musculus transcribed sequences
128
2.2
BB538816


Aif1
Aif1
allograft inflammatory factor 1
71
36.5
NM_019467


Aim1
Aim1
absent in melanoma 1
294
2.8
BM233292


Akr1c20
Akr1c20
aldo-keto reductase family 1, member
28
8.0
BC021607




C20


Akt3
Akt3
thymoma viral proto-oncogene 3
60
3.2
AF124142


Akt3
Akt3
thymoma viral proto-oncogene 3
47
4.1
AF124142


Sdccag8
Akt3
serologically defined colon cancer
171
3.6
BB521695




antigen 8


AL024069
AL024069
expressed sequence AL024069
314
2.8
AI504908


Aldh1a2
Aldh1a2
aldehyde dehydrogenase family 1,
303
5.9
NM_009022




subfamily A2


Aldh1b1
Aldh1b1
aldehyde dehydrogenase 1 family,
115
2.7
BC020001




member B1


Alox5ap
Alox5ap
arachidonate 5-lipoxygenase activating
181
13.7
BC026209




protein


Ankrd1
Ankrd1
ankyrin repeat domain 1 (cardiac muscle)
44
5.7
AK009959


2900037I21Rik
Anln
RIKEN cDNA 2900037I21 gene
62
7.4
BI690018


Anp32b
Anp32b
acidic nuclear phosphoprotein 32 family,
1716
2.1
NM_130889




member B


Anxa1
Anxa1
annexin A1
878
2.9
NM_010730


Anxa2
Anxa2
annexin A2
2454
2.9
NM_007585


Ap1s2
Ap1s2
adaptor-related protein complex 1, sigma
188
2.0
BE655707




2 subunit


Ap1s2
Ap1s2; EST1;
adaptor-related protein complex 1, sigma
151
6.4
AK005223



1500012A13Rik
2 subunit


Apaf1
Apaf1
apoptotic protease activating factor 1
274
2.1
AK018076


Apob48r
Apob48r
apolipoprotein B48 receptor
95
3.6
NM_138310


Apobec1
Apobec1
apolipoprotein B editing complex 1
235
3.2
BC003792


App
App
amyloid beta (A4) precursor protein
26
2.3
AV348729


Arf3
Arf3
ADP-ribosylation factor 3
107
2.4
BQ175059


Arf6
Arf6
ADP-ribosylation factor 6
3548
2.1
BI248938


Arg2
Arg2
arginase type II
85
4.3
AV002218


Arg2
Arg2
arginase type II
145
4.3
NM_009705


6530401L14Rik
Arhgap11a
RIKEN cDNA 6530401L14 gene
62
8.0
AV349116


—
Arhgap15

Mus musculus 16 days neonate thymus
38
5.4
BB234837




cDNA, RIKEN full-length enriched library,




clone: A130024J05 product: hypothetical




protein, full insert sequence


—
Arhgap15

Mus musculus 16 days neonate thymus
58
3.1
BB234837




cDNA, RIKEN full-length enriched library,




clone: A130024J05 product: hypothetical




protein, full insert sequence


4933411B03Rik
Arhgap19
RIKEN cDNA 4933411B03 gene
35
4.1
BG072763


A130039I20Rik
Arhgap25
RIKEN cDNA A130039I20 gene
84
3.7
BM241218


Arhgap4
Arhgap4
Rho GTPase activating protein 4
117
2.6
NM_138630


AU043488
Arhgap9
expressed sequence AU043488
84
8.7
BB327418


Gli
Arhgap9
GLI-Kruppel family member GLI
24
11.5
AU043488


Gli
Arhgap9
GLI-Kruppel family member GLI
12
14.6
AU043488


Arhgdib
Arhgdib
Rho, GDP dissociation inhibitor (GDI)
1160
7.7
AK002516




beta


Arhgef6
Arhgef6
Rac/Cdc42 guanine nucleotide exchange
142
4.5
BM246754




factor (GEF) 6


D430024K22Rik
Arid5a
RIKEN cDNA D430024K22 gene
56
8.3
BC027152


Desrt
Arid5b
developmentally and sexually retarded
19
2.7
BB257077




with transient immune abnormalities


A630084M22Rik
Arl7
RIKEN cDNA A630084M22 gene
254
2.8
BQ176306


1200015K23Rik
Armc8
RIKEN cDNA 1200015K23 gene
115
2.2
BE995635


Arrb2
Arrb2
arrestin, beta 2
240
3.5
BC016642


Arts1
Arts1
type 1 tumor necrosis factor receptor
444
4.8
NM_030711




shedding aminopeptidase regulator


Arts1
Arts1
type 1 tumor necrosis factor receptor
221
4.1
AV287655




shedding aminopeptidase regulator


Asf1b
Asf1b
ASF1 anti-silencing function 1 homolog B
111
5.0
BC003428




(S. cerevisiae)


Asns
Asns
asparagine synthetase
329
2.3
BC005552


Asns
Asns
asparagine synthetase
103
4.0
AV212753


2610509G12Rik
Atad2
RIKEN cDNA 2610509G12 gene
127
6.0
BM206009


Atf3
Atf3
activating transcription factor 3
109
6.6
BC019946


Atp10a
Atp10a
ATPase, class V, type 10A
37
5.7
BB487289


Atp10a
Atp10a
ATPase, class V, type 10A
26
3.5
BM249532


Atp8b2
Atp8b2
Atpase, class I, type 8B, member 2
248
2.6
BQ178970


—
Atr

Mus musculus 16 days neonate thymus
33
2.3
BM197239




cDNA, RIKEN full-length enriched library,




clone: A130049K15




product: unclassifiable, full insert




sequence


—
AU020206

Mus musculus 3 days neonate thymus
172
10.7
BI151331




cDNA, RIKEN full-length enriched library,




clone: A630040D01 product: unknown




EST, full insert sequence


Aurkb
Aurkb
aurora kinase B
21
9.6
BC003261


Aurkb
Aurkb
aurora kinase B
30
11.7
BC003261


—
AW049306

Mus musculus transcribed sequences
20
3.9
BE457612


—
AW112010

Mus musculus transcribed sequences
438
32.5
BE688358


—
AW121567

Mus musculus 12 days embryo spinal
33
2.9
BB461295




ganglion cDNA, RIKEN full-length




enriched library, clone: D130071A17




product: unknown EST, full insert




sequence


AW212607
AW212607
expressed sequence AW212607
64
3.1
AV325152


AW212607
AW212607
expressed sequence AW212607
74
5.9
BB308532


1810048P08Rik
AW490415
RIKEN cDNA 1810048P08 gene
49
3.2
AK010874


—
AW492955

Mus musculus transcribed sequences
182
2.1
AW492955


—
AW547186

Mus musculus 13 days embryo male
47
3.4
BB044338




testis cDNA, RIKEN full-length enriched




library, clone: 6030487A22




product: unclassifiable, full insert




sequence


Srr
AW550801
serine racemase
191
2.3
BM213835


Axud1
Axud1
AXIN1 up-regulated 1
100
4.5
BG070296


IkappaBNS
AY078069
NF-kappa B inhibitor
26
9.0
AW495632


B230217C12Rik
B230217C12Rik
RIKEN cDNA B230217C12 gene
24
6.2
BB376573


Cugbp2
8230218O03
CUG triplet repeat, RNA binding protein 2
91
8.2
BB644164


Cugbp2
8230218O03
CUG triplet repeat, RNA binding protein 2
161
7.9
BB644164


B230315M08Rik
B230315M08Rik
RIKEN cDNA B230315M08 gene
113
2.8
AI536469


B2m
B2m
beta-2 microglobulin
71
11.6
AA170322


B2m
B2m
beta-2 microglobulin
9650
2.7
AI099111


B3gnt5
B3gnt5
UDP-GlcNAc: betaGal beta-1,3-N-
40
3.7
BM214359




acetylglucosaminyltransferase 5


Bak1
Bak1
BCL2-antagonist/killer 1
113
2.1
AF402617


Bak1
Bak1
BCL2-antagonist/killer 1
93
5.6
NM_007523


A530094C12Rik
Bank1
RIKEN cDNA A530094C12 gene
74
2.0
AI451642


—
Basp1

Mus musculus 10 days neonate medulla
143
9.4
AK011545




oblongata cDNA, RIKEN full-length




enriched library, clone: B830039F09




product: BRAIN ACID SOLUBLE




PROTEIN 1 (BASP1 PROTEIN)




(NEURONAL AXONAL MEMBRANE




PROTEIN NAP-22) homolog [Rattus





norvegicus], full insert sequence


BB146404
BB146404
expressed sequence BB146404
17
4.5
BC025893


—
BB220380

Mus musculus adult male bone cDNA,
33
3.7
AV281292




RIKEN full-length enriched library,




clone: 9830142N16




product: unclassifiable, full insert




sequence


BC003236
BC003236
cDNA sequence BC003236
999
2.4
BB231897


BC004701
BC004701
cDNA sequence BC004701
41
5.9
BC004701


BC006779
BC006779
cDNA sequence BC006779
296
3.8
BE853170


BC010462
BC010462
cDNA sequence BC010462
208
3.5
BC010462


A530020G20Rik
BC010552
RIKEN cDNA A530020G20 gene
21
3.3
AV256906


BC010552
BC010552
cDNA sequence BC010552
133
3.6
BC025548


BC013672
BC013672
cDNA sequence BC013672
9
8.7
BC013672


BC013712
BC013712
cDNA sequence BC013712
130
12.3
BB262491


BC023105
BC023105
cDNA sequence BC023105
46
70.3
BC023105


BC023179
BC023179
cDNA sequence BC023179
39
2.0
BC023179


BC023741
BC023741
cDNA sequence BC023741
208
11.7
BB705351


BC023882
BC023882
cDNA sequence BC023882
238
2.8
BC027393


BC027057
BC027057
cDNA sequence BC027057
80
3.1
BE133443


BC027057
BC027057
cDNA sequence BC027057
33
8.4
BB040051


L259
BC028528
L259
146
4.1
BC028528


BC031748
BC031748
cDNA sequence BC031748
46
2.5
BB709811


—
BC031781
—
246
2.0
AV312901


BC032204
BC032204
cDNA sequence BC032204
91
9.3
BG066664


—
BC033596

Mus musculus 16 days neonate thymus
56
2.6
BB162048




cDNA, RIKEN full-length enriched library,




clone: A130086M19 product: unknown




EST, full insert sequence


BC037703
BC037703
cDNA sequence BC037703
87
2.5
AV231983


9830126M18
BC052328
hypothetical protein 9830126M18
113
6.4
BM224662


B930060C03
BC065123
hypothetical protein B930060C03
354
3.9
BM239162


Baz1a
BC065123
bromodomain adjacent to zinc finger
340
2.5
AV357135




domain 1A


4732427B05
BC066140
hypothetical protein 4732427B05
68
2.3
AV114409


—
BC067047

Mus musculus adult male testis cDNA,
142
3.6
BB794978




RIKEN full-length enriched library,




clone: 4930413J11 product: mitochondria




located 1 homolog (human), full insert




sequence


—
BC068171

Mus musculus similar to DYSKERIN
501
2.2
BG068512




(LOC245474), mRNA


Bcl11b
Bcl11b
B-cell leukemia/lymphoma 11B
160
2.2
BM117007


Bcl2l11
Bcl2l11
BCL2-like 11 (apoptosis facilitator)
62
2.6
BB667581


Bcl2l11
Bcl2l11
BCL2-like 11 (apoptosis facilitator)
114
3.4
BM120925


Bcl2l11
Bcl2l11
BCL2-like 11 (apoptosis facilitator)
481
2.5
BM120925


Bcl2l11
Bcl2l11
BCL2-like 11 (apoptosis facilitator)
401
3.9
BB667581


Bcl3
Bcl3
B-cell leukemia/lymphoma 3
203
3.8
NM_033601


Bcor
Bcor
Bcl6 interacting corepressor
181
2.2
AK018370


Bgn
Bgn
biglycan
2040
3.2
AI931862


Bgn
Bgn
biglycan
2268
2.8
BC019502


Birc1b
Birc1b
baculoviral IAP repeat-containing 1b
148
2.3
NM_010872


Birc1e
Birc1e
baculoviral IAP repeat-containing 1e
59
2.2
NM_010870


Birc1f
Birc1f
baculoviral IAP repeat-containing 1f
79
2.5
AI451585


Birc3
Birc2
baculoviral IAP repeat-containing 3
824
2.3
NM_007465


Birc2
Birc3
baculoviral IAP repeat-containing 2
628
5.7
NM_007464


Birc5
Birc5
baculoviral IAP repeat-containing 5
58
18.6
BC004702


Bnip2
Bnip2
BCL2/adenovirus E1B 19 kDa-interacting
724
2.4
AV144704




protein 1, NIP2


Bnip2
Bnip2; Nip21;
BCL2/adenovirus E1B 19 kDa-interacting
667
2.2
AK014659



BNIP2beta;
protein 1, NIP2



5730523P12Rik


2310015I10Rik
Brd4
RIKEN cDNA 2310015I10 gene
269
13.8
BC008532


A730011O11Rik
Brrn1
RIKEN cDNA A730011O11 gene
204
4.6
BB725358


A730011O11Rik
Brrn1
RIKEN cDNA A730011O11 gene
81
3.6
BC021499


Bspry
Bspry
B-box and SPRY domain containing
552
3.3
NM_138653


Bst1
Bst1
bone marrow stromal cell antigen 1
167
4.5
AI647987


Btg1
Btg1
B-cell translocation gene 1, anti-
3872
2.3
L16846




proliferative


Btk
Btk
Bruton agammaglobulinemia tyrosine
26
8.8
NM_013482




kinase


Btla
Btla
B and T lymphocyte associated
91
7.9
BM240873


Bub1b
Bub1b
budding uninhibited by benzimidazoles 1
6
12.3
AU045529




homolog, beta (S. cerevisiae)


Bub3
Bub3
budding uninhibited by benzimidazoles 3
20
3.6
BB449877




homolog (S. cerevisiae)


Bzrp
Bzrp
benzodiazepine receptor, peripheral
1248
2.1
BB132602


—
C030046G05

Mus musculus adult male corpus striatum
89
3.4
BE691546




cDNA, RIKEN full-length enriched library,




clone: C030046G05 product: unknown




EST, full insert sequence


C130032J12Rik
C130032J12Rik
RIKEN cDNA C130032J12 gene
202
2.0
BB192700


C130036J11
C130036J11
hypothetical protein C130036J11
8
8.1
BB072624


C1qa
C1qa
complement component 1, q
489
8.8
NM_007572




subcomponent, alpha polypeptide


C1qb
C1qb
complement component 1, q
147
34.3
BB111335




subcomponent, beta polypeptide


C1qb
C1qb
complement component 1, q
420
6.7
AW227993




subcomponent, beta polypeptide


C1qb
C1qb
complement component 1, q
363
14.1
NM_009777




subcomponent, beta polypeptide


C1qg
C1qg
complement component 1, q
185
20.8
NM_007574




subcomponent, gamma polypeptide


C1r
C1r
complement component 1, r
382
9.4
NM_023143




subcomponent


C1s
C1s
complement component 1, s
395
12.7
BC022123




subcomponent


C2
C2
complement component 2 (within H-2S)
1215
3.5
NM_013484


—
C2
—
1241
4.6
AV290571


—
C2
—
855
4.4
AV227574


C2ta
C2ta
class II transactivator
43
13.2
AF042158


C2ta
C2ta
class II transactivator
89
10.8
AF042158


C3
C3
complement component 3
437
29.7
K02782


C330012H03Rik
C330012H03Rik
RIKEN cDNA C330012H03 gene
69
2.8
BB098431


C330027C09Rik
C330027C09Rik
RIKEN cDNA C330027C09 gene
53
5.5
AU018569


C3ar1
C3ar1
complement component 3a receptor 1
113
3.5
NM_009779


C3ar1
C3ar1
complement component 3a receptor 1
38
10.2
BB333624


C3ar1
C3ar1
complement component 3a receptor 1
50
10.0
NM_009779


C4
C4
complement component 4 (within H-2S)
894
8.4
NM_009780


C5r1
C5r1; C5aR;
complement component 5, receptor 1
41
3.4
NM_007577



Cd88


C630016B22Rik
C630016B22Rik
RIKEN cDNA C630016B22 gene
523
2.0
BB711990


C630016B22Rik
C630016B22Rik
RIKEN cDNA C630016B22 gene
786
2.3
BB771888


—
C730049O14Rik

Mus musculus adult male liver tumor
167
4.8
BB200607




cDNA, RIKEN full-length enriched library,




clone: C730049O14 product: unknown




EST, full insert sequence


C79407
C79407
expressed sequence C79407
51
3.3
BB540053


C79407
C79407
expressed sequence C79407
45
6.4
BE951628


—
C79445

Mus musculus 18-day embryo whole
166
3.7
C79445




body cDNA, RIKEN full-length enriched




library, clone: 1100001P14




product: TUBULIN, BETA 5 homolog




[Homo sapiens], full insert sequence


C80638
C80638
expressed sequence C80638
38
3.5
AV251613


B130036O03
C86302
hypothetical protein B130036O03
256
2.6
BB295220


—
C86813; FM2;
—
45
3.0
C86813



lerepo1


—
C86813; FM2;
—
284
5.6
C86813



lerepo1


—
Cacnb2

Mus musculus adult male hippocampus
7
2.8
AV154947




cDNA, RIKEN full-length enriched library,




clone: 2900072G11 product: unknown




EST, full insert sequence


Calm1
Calm1
calmodulin 1
2311
2.2
AU079514


Calmbp1
Calmbp1
calmodulin binding protein 1
21
4.2
BB648052


E030025C11Rik
Camk1d
RIKEN cDNA E030025C11 gene
47
4.7
BG071931


Camk2d
Camk2d
calcium/calmodulin-dependent protein
69
2.0
BB373572




kinase II, delta


Capg
Capg
capping protein (actin filament), gelsolin-
221
7.7
NM_007599




like


Capg
Capg
capping protein (actin filament), gelsolin-
77
2.1
BB136012




like


Cappa1
Capza1
capping protein alpha 1
2195
2.5
AV267494


—
Capza1
—
2695
2.2
AI463215


Car13
Car13
carbonic anhydrase 13
132
2.3
AK010166


Card11
Card11
caspase recruitment domain family,
24
4.6
AV095659




member 11


Card4
Card4
caspase recruitment domain 4
228
3.2
BB138330


Casp1
Casp1
caspase 1
94
9.4
BC008152


Casp12
Casp12
caspase 12
122
3.6
NM_009808


Casp12
Casp12
caspase 12
145
6.8
NM_009808


Casp3
Casp3
caspase 3, apoptosis related cysteine
312
2.2
D86352




protease


Casp3
Casp3
caspase 3, apoptosis related cysteine
707
2.6
BG070529




protease


Casp4
Casp4
caspase 4, apoptosis-related cysteine
82
13.6
NM_007609




protease


Casp7
Casp7
caspase 7
234
3.7
U67321


Casp7
Casp7
caspase 7
528
2.8
NM_007611


Cbfb
Cbfb
core binding factor beta
1387
2.3
NM_022309


—
Cblb

Mus musculus transcribed sequences
134
3.5
BB205662


Cblb
Cblb
Casitas B-lineage lymphoma b
258
2.1
AW545867


Ccl11
Ccl11
small chemokine (C—C motif) ligand 11
21
4.7
NM_011330


Ccl12
Ccl12
chemokine (C—C motif) ligand 12
11
49.6
U50712


Ccl2
Ccl2
chemokine (C—C motif) ligand 2
43
28.9
AF065933


Ccl4
Ccl4
chemokine (C—C motif) ligand 4
95
4.5
AF128218


Ccl5
Ccl5
chemokine (C—C motif) ligand 5
34
140.5
NM_013653


Ccl6
Ccl6
chemokine (C—C motif) ligand 6
85
8.9
BC002073


Ccl7
Ccl7
chemokine (C—C motif) ligand 7
54
6.2
AF128193


Ccl8
Ccl8
chemokine (C—C motif) ligand 8
115
16.0
NM_021443


Ccl9
Ccl9
chemokine (C—C motif) ligand 9
25
15.6
AF128196


Ccl9
Ccl9
chemokine (C—C motif) ligand 9
70
9.8
AF128196


Ccnb1
Ccnb1
cyclin B1
102
7.1
NM_007629


Ccnb1
Ccnb1
cyclin B1
55
12.1
NM_007629


Ccnb1
Ccnb1
cyclin B1
14
22.1
AU015121


Ccnd2
Ccnd2
cyclin D2
420
2.3
BQ175880


—
Ccne1
—
70
3.9
BB293079


Ccne2
Ccne2
cyclin E2
47
4.5
AF091432


Ccnf
Ccnf
cyclin F
11
9.5
NM_007634


Ccr1
Ccr1
chemokine (C—C motif) receptor 1
81
9.2
AV231648


Ccr2
Ccr2
chemokine (C—C) receptor 2
123
23.0
BB148128


Ccr2
Ccr2
chemokine (C—C) receptor 2
87
7.6
BB148128


Ccr2
Ccr2
chemokine (C—C) receptor 2
70
24.5
BB148128


Ccr5
Ccr5
chemokine (C—C motif) receptor 5
41
16.8
X94151


Ccr5
Ccr5
chemokine (C—C motif) receptor 5
31
7.6
X94151


Ccr5
Ccr5
chemokine (C—C motif) receptor 5
73
18.6
D83648


Ccr9
Ccr9
chemokine (C—C motif) receptor 9
30
4.6
AJ131357


Ccrl2
Ccrl2
chemokine (C—C motif) receptor-like 2
138
2.5
AJ318863


Cd14
Cd14
CD14 antigen
359
16.5
NM_009841


Cd160
Cd160
CD160 antigen
121
2.4
NM_018767


Cd160
Cd160
CD160 antigen
16
9.7
AU045688


Cd1d1
Cd1d1
CD1d1 antigen
67
4.1
NM_007639


Mox2
Cd200
antigen identified by monoclonal antibody
591
2.2
AF004023




MRC OX-2


F630003A18Rik
Cd200r1
RIKEN cDNA F630003A18 gene
21
5.2
BB770873


Cd22
Cd22
CD22 antigen
97
2.0
AF102134


Cd244
Cd244
CD244 natural killer cell receptor 2B4
14
7.0
NM_018729


Cd28
Cd28
CD28 antigen
16
26.5
AV313615


Cd28
Cd28
CD28 antigen
43
22.1
NM_007642


Cd38
Cd38
CD38 antigen
191
2.7
NM_007646


Cd38
Cd38
CD38 antigen
455
3.7
BB256012


Cd3e
Cd3e
CD3 antigen, epsilon polypeptide
31
27.4
NM_007648


Cd44
Cd44
CD44 antigen
117
15.9
AW146109


Cd47
Cd47
CD47 antigen (Rh-related antigen,
1584
2.1
NM_010581




integrin-associated signal transducer)


Cd47
Cd47
CD47 antigen (Rh-related antigen,
2922
2.4
NM_010581




integrin-associated signal transducer)


Cd48
Cd48
CD48 antigen
82
20.7
BE634960


Cd5
Cd5
CD5 antigen
77
6.3
NM_007650


Cd52
Cd52
CD52 antigen
474
28.2
NM_013706


—
Cd53

Mus musculus transcribed sequences
13
7.7
BM239715


Cd6
Cd6
CD6 antigen
18
11.9
U12434


Cd68
Cd68
CD68 antigen
189
7.9
BC021637


Cd69
Cd69
CD69 antigen
22
13.0
AK017979


Cd72
Cd72
CD72 antigen
51
10.7
BC003824


Cd79b
Cd79b
CD79B antigen
54
2.7
NM_008339


Cd83
Cd83
CD83 antigen
94
7.4
NM_009856


Cd84
Cd84
CD84 antigen
44
8.2
NM_013489


Cd86
Cd86
CD86 antigen
53
10.4
NM_019388


Cd86
Cd86
CD86 antigen
38
11.2
NM_019388


Cd8a
Cd8a
CD8 antigen, alpha chain
96
11.3
BB154331


Cd8a
Cd8a
CD8 antigen, alpha chain
71
18.2
M12825


Cd8a
Cd8a
CD8 antigen, alpha chain
60
31.2
M12825


1700109I12Rik
Cd96
RIKEN cDNA 1700109I12 gene
99
2.9
NM_032465


Elovl1
Cdc20
elongation of very long chain fatty acids
307
5.7
BB041150




(FEN1/Elo2, SUR4/Elo3, yeast)-like 1


Cdc20
Cdc20
cell division cycle 20 homolog (S. cerevisiae)
302
3.1
NM_023223


Cdc25b
Cdc25b
cell division cycle 25 homolog B (S. cerevisiae)
110
2.8
NM_023117


Cdc2a
Cdc2a
cell division cycle 2 homolog A (S. pombe)
170
5.9
NM_007659


Cdc45l
Cdc45l
cell division cycle 45 homolog (S. cerevisiae)-
104
2.8
NM_009862




like


Cdc7
Cdc7
cell division cycle 7 (S. cerevisiae)
45
5.1
AB018574


2610311M19Rik
Cdca2
RIKEN cDNA 2610311M19 gene
58
5.2
BG065056


2610311M19Rik
Cdca2
RIKEN cDNA 2610311M19 gene
27
6.7
BG065056


Cdca3
Cdca3
cell division cycle associated 3
200
3.4
BI081061


Cdca4
Cdca4
cell division cycle associated 4
200
2.1
BB329505


Cdca4
Cdca4
cell division cycle associated 4
280
3.2
AF322238


D4Ertd421e
Cdca8
DNA segment, Chr 4, ERATO Doi 421,
57
12.2
AV307110




expressed


D4Ertd421e
Cdca8
DNA segment, Chr 4, ERATO Doi 421,
105
8.3
BB702047




expressed


D4Ertd421e
Cdca8
DNA segment, Chr 4, ERATO Doi 421,
67
4.8
AV307110




expressed


Cdh11
Cdh11
cadherin 11
381
2.8
NM_009866


Cdk6
Cdk6
cyclin-dependent kinase 6
16
3.0
NM_009873


Cdkn1a
Cdkn1a
cyclin-dependent kinase inhibitor 1A
231
3.9
AK007630




(P21)


Cds1
Cds1
CDP-diacylglycerol synthase 1
324
2.0
BI152841


Cdyl
Cdyl
chromodomain protein, Y chromosome-
188
2.1
AF081260




like


Cebpb
Cebpb
CCAAT/enhancer binding protein
672
3.6
NM_009883




(C/EBP), beta


Cebpb
Cebpb
CCAAT/enhancer binding protein
214
2.9
AB012278




(C/EBP), beta


Cebpd
Cebpd
CCAAT/enhancer binding protein
236
5.5
BB831146




(C/EBP), delta


Cenpa
Cenpa
centromere autoantigen A
75
8.8
AV132173


BC049989
Cenpe
cDNA sequence BC049989
13
2.3
BG068387


BC049989
Cenpe
cDNA sequence BC049989
136
3.1
BG916502


Lek1
Cenpf
leucine, glutamic acid, lysine family 1
89
3.4
BE848253




protein


Cenph
Cenph
centromere autoantigen H
22
5.1
BC025084


Centb1
Centb1
centaurin, beta 1
228
2.4
BB757196


Kctd11
Centb1
potassium channel tetramerisation
110
5.9
BB115902




domain containing 11


AA968343
Cep1
expressed sequence AA968343
166
2.2
BB466021


Cfi
Cfi
complement component factor i
364
3.3
NM_007686


Ch25h
Ch25h
cholesterol 25-hydroxylase
90
17.6
NM_009890


Chaf1b
Chaf1b
chromatin assembly factor 1, subunit B
81
3.3
BC013532




(p60)


Chek1
Chek1
checkpoint kinase 1 homolog (S. pombe)
29
4.7
NM_007691


Chi3l3
Chi3l3
chitinase 3-like 3
15
64.7
NM_009892


Chi3l4
Chi3l4
chitinase 3-like 4
76
13.4
AY065557


Chsy1
Chsy1
carbohydrate (chondroitin) synthase 1
640
2.0
BQ174991


Ckap2
Ckap2
cytoskeleton associated protein 2
121
2.8
BM208103


1700001C14Rik
Cklf
RIKEN cDNA 1700001C14 gene
169
2.1
AY047360


Cklfsf7
Cklfsf7
chemokine-like factor super family 7
48
3.2
BC026773


Cks1
Cks1b
CDC28 protein kinase 1
181
4.6
NM_016904


Cks1
Cks1b
CDC28 protein kinase 1
323
6.2
NM_016904


Clca2
Clca2
chloride channel calcium activated 2
39
3.1
AF108501


Cldn1
Cldn1
claudin 1
471
3.0
AV227581


Clecsf10
Clecsf10
C-type (calcium dependent, carbohydrate
68
6.8
NM_020001




recognition domain) lectin, superfamily




member 10


Clecsf10
Clecsf10
C-type (calcium dependent, carbohydrate
16
11.7
AF240358




recognition domain) lectin, superfamily




member 10


Clecsf12
Clecsf12
C-type (calcium dependent, carbohydrate
197
9.5
NM_020008




recognition domain) lectin, superfamily




member 12


Clecsf5
Clecsf5
C-type (calcium dependent,
56
10.9
NM_021364




carbohydrate-recognition domain) lectin,




superfamily member 5


1810046I24Rik
Clecsf6
RIKEN cDNA 1810046I24 gene
29
7.2
BC006623


Clecsf6
Clecsf6
C-type (calcium dependent, carbohydrate
65
4.6
NM_011999




recognition domain) lectin, superfamily




member 6


Clecsf8
Clecsf8
C-type (calcium dependent, carbohydrate
25
4.5
NM_010819




recognition domain) lectin, superfamily




member 8


Clecsf9
Clecsf9
C-type (calcium dependent, carbohydrate
38
3.4
NM_019948




recognition domain) lectin, superfamily




member 9


Clecsf9
Clecsf9
C-type (calcium dependent, carbohydrate
17
30.6
NM_019948




recognition domain) lectin, superfamily




member 9


Clic1
Clic1
chloride intracellular channel 1
3468
2.6
NM_033444


E130314M08Rik
Clspn
RIKEN cDNA E130314M08 gene
40
7.0
BG067086


Cnn2
Cnn2
calponin 2
626
3.8
BI663014


4932442K20Rik
Cnot6l
RIKEN cDNA 4932442K20 gene
322
2.0
BC018506


Cnp1
Cnp1
cyclic nucleotide phosphodiesterase 1
113
2.5
M58045


Col15a1
Col15a1
procollagen, type XV
247
2.1
AF011450


Col1a2
Col1a2
procollagen, type I, alpha 2
1460
4.5
BF227507


Col1a2
Col1a2
procollagen, type I, alpha 2
392
8.6
BF227507


Col3a1
Col3a1
procollagen, type III, alpha 1
165
7.9
AW550625


Col3a1
Col3a1
procollagen, type III, alpha 1
1468
5.7
AW550625


Col5a1
Col5a1
procollagen, type V, alpha 1
242
3.6
AW744319


Col5a2
Col5a2
procollagen, type V, alpha 2
65
3.8
AV229424


Col5a2
Col5a2
procollagen, type V, alpha 2
150
6.7
AV229424


Col6a2
Col6a2
procollagen, type VI, alpha 2
363
3.4
BI455189


Col6a3
Col6a3
procollagen, type VI, alpha 3
657
2.6
AF064749


—
Col8a1

Mus musculus 6 days neonate head
211
4.4
AV292255




cDNA, RIKEN full-length enriched library,




clone: 5430419M07 product: unknown




EST, full insert sequence


Colec12
Colec12
collectin sub-family member 12
134
2.4
NM_130449


Copeb
Copeb
core promoter element binding protein
198
4.4
AF072403


Copeb
Copeb
core promoter element binding protein
501
6.3
AV025472


Copeb
Copeb
core promoter element binding protein
298
5.5
NM_011803


Coro1a
Coro1a
coronin, actin binding protein 1A
26
3.9
BB740218


Coro1a
Coro1a
coronin, actin binding protein 1A
168
24.0
BB740218


5830400N10Rik
Coro2a
RIKEN cDNA 5830400N10 gene
69
4.1
AU042532


5830400N10Rik
Coro2a
RIKEN cDNA 5830400N10 gene
68
4.2
AI316747


Cp
Cp
ceruloplasmin
727
3.9
BB009037


Cpne2
Cpne2
copine II
100
1.9
BC023348


Crem
Crem
cAMP responsive element modulator
373
3.3
AI467599


Crem
Crem
cAMP responsive element modulator
221
3.3
AI467599


Crip1
Crip1
cysteine-rich protein 1 (intestinal)
1191
3.7
NM_007763


Crlf1
Crlf1
cytokine receptor-like factor 1
63
10.0
NM_018827


—
Crlf3

Mus musculus transcribed sequences
110
2.8
BG094104


Crlf3
Crlf3
cytokine receptor-like factor 3
426
2.4
BB161253


Crtam
Crtam
cytotoxic and regulatory T cell molecule
54
5.0
NM_019465


Csf1
Csf1
colony stimulating factor 1 (macrophage)
138
2.9
BM233698


Csf1
Csf1
colony stimulating factor 1 (macrophage)
73
3.2
M21149


Csf1
Csf1
colony stimulating factor 1 (macrophage)
213
5.5
BM233698


Csf2rb1
Csf2rb1
colony stimulating factor 2 receptor, beta
7
11.5
NM_007780




1, low-affinity (granulocyte-macrophage)


Csf2rb1
Csf2rb1
colony stimulating factor 2 receptor, beta
68
14.7
BB769628




1, low-affinity (granulocyte-macrophage)


Csf2rb2
Csf2rb2
colony stimulating factor 2 receptor, beta
43
11.4
NM_007781




2, low-affinity (granulocyte-macrophage)


Csf3r
Csf3r
colony stimulating factor 3 receptor
26
12.4
NM_007782




(granulocyte)


Cspg2
Cspg2
chondroitin sulfate proteoglycan 2
42
7.2
NM_019389


Cspg2
Cspg2
chondroitin sulfate proteoglycan 2
59
8.2
BM251152


Cstb
Cstb
cystatin B
5561
2.3
NM_007793


Cstb
Cstb
cystatin B
2587
2.9
NM_007793


Cstf3
Cstf3
cleavage stimulation factor, 3′ pre-RNA,
51
2.5
BM218423




subunit 3


Tpbpb
Ctla2a
trophoblast specific protein beta
81
2.9
BG064656


Ctla4
Ctla4
cytotoxic T-lymphocyte-associated
26
21.0
NM_009843




protein 4


—
Ctsc

Mus musculus transcribed sequences
11
14.6
BG070233


Ctsc
Ctsc
cathepsin C
1593
8.7
NM_009982


—
Ctsc

Mus musculus transcribed sequences
32
5.3
AV367948


—
Ctsc

Mus musculus transcribed sequences
98
6.5
BM237633


Ctss
Ctss
cathepsin S
838
16.7
NM_021281


Cx3cl1
Cx3cl1
chemokine (C—X3—C motif) ligand 1
705
2.4
AF010586


Cx3cr1
Cx3cr1
chemokine (C—X3—C) receptor 1
139
2.4
BC012653


Cxcl1
Cxcl1
chemokine (C—X—C motif) ligand 1
177
2.7
BB554288


Cxcl1
Cxcl1
chemokine (C—X—C motif) ligand 1
74
6.2
NM_008176


Cxcl10
Cxcl10
chemokine (C—X—C motif) ligand 10
162
81.6
NM_021274


Cxcl11
Cxcl11
chemokine (C—X—C motif) ligand 11
46
10.5
NM_019494


Cxcl11
Cxcl11
chemokine (C—X—C motif) ligand 11
144
99.2
NM_019494


Cxcl13
Cxcl13
chemokine (C—X—C motif) ligand 13
68
4.4
AF030636


Cxcl14
Cxcl14
chemokine (C—X—C motif) ligand 14
260
3.1
AF252873


Cxcl14
Cxcl14
chemokine (C—X—C motif) ligand 14
124
9.2
AF252873


Cxcl16
Cxcl16
chemokine (C—X—C motif) ligand 16
1027
2.9
BC019961


Cxcl16
Cxcl16
chemokine (C—X—C motif) ligand 16
1429
3.7
BC019961


Cxcl16
Cxcl16
chemokine (C—X—C motif) ligand 16
199
2.9
AI662455


Cxcl9
Cxcl9
chemokine (C—X—C motif) ligand 9
125
176.4
NM_008599


Cxcr3
Cxcr3
chemokine (C—X—C motif) receptor 3
137
10.2
NM_009910


Cxcr4
Cxcr4
chemokine (C—X—C motif) receptor 4
133
3.6
D87747


Cybb
Cybb
cytochrome b-245, beta polypeptide
283
21.3
AV373944


Cybb
Cybb
cytochrome b-245, beta polypeptide
153
14.2
NM_007807


Cybb
Cybb
cytochrome b-245, beta polypeptide
161
9.1
AV373944


Cyp1b1
Cyp1b1
cytochrome P450, family 1, subfamily b,
259
3.4
BI251808




polypeptide 1


Cyp4f18
Cyp4f18
cytochrome P450, family 4, subfamily f,
19
26.1
NM_024444




polypeptide 18


Cyp4v3
Cyp4v3
cytochrome P450, family 4, subfamily v,
300
3.1
NM_133969




polypeptide 3


Cyp4v3
Cyp4v3
cytochrome P450, family 4, subfamily v,
137
3.9
NM_133969




polypeptide 3


Cyr61
Cyr61
cysteine rich protein 61
384
2.5
BM202770


Cysltr1
Cysltr1
cysteinyl leukotriene receptor 1
13
4.8
BC027102


Cysltr1
Cysltr1
cysteinyl leukotriene receptor 1
12
4.9
BC027102


—
D030064D06Rik

Mus musculus 9 days embryo whole
92
2.3
AW987520




body cDNA, RIKEN full-length enriched




library, clone: D030064D06




product: unknown EST, full insert




sequence


D11Ertd461e
D11Ertd461e
DNA segment, Chr 11, ERATO Doi 461,
26
5.5
C87579




expressed


D11Ertd759e
D11Ertd759e
DNA segment, Chr 11, ERATO Doi 759,
922
4.9
AW556558




expressed


D11Lgp2e
D11Lgp2e
DNA segment, Chr 11, Lothar
27
6.1
NM_030150




Hennighausen 2, expressed


D11Lgp2e
D11Lgp2e
DNA segment, Chr 11, Lothar
55
10.0
AF316999




Hennighausen 2, expressed


D11Wsu99e
D11Wsu99e
DNA segment, Chr 11, Wayne State
232
2.6
AV225714




University 99, expressed


D12Ertd551e
D12Ertd551e
DNA segment, Chr 12, ERATO Doi 551,
660
2.1
BI102044




expressed


—
D12Ertd551e

Mus musculus adult male tongue cDNA,
20
5.5
BQ175646




RIKEN full-length enriched library,




clone: 2310058N22 product: unknown




EST, full insert sequence


D12Ertd647e
D12Ertd647e
DNA segment, Chr 12, ERATO Doi 647,
953
5.8
AW554405




expressed


D12Ertd647e
D12Ertd647e
DNA segment, Chr 12, ERATO Doi 647,
1414
4.1
BI655075




expressed


4930513H15Rik
D14Ertd581e
RIKEN cDNA 4930513H15 gene
49
2.1
AK017117


D16Ertd472e
D16Ertd472e
DNA segment, Chr 16, ERATO Doi 472,
105
4.2
AV381575




expressed


D17H6S56E-5
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
381
5.9
NM_033075


D17H6S56E-5
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
195
9.2
NM_033075


D2Ertd750e
D2Ertd750e
DNA segment, Chr 2, ERATO Doi 750,
43
7.9
AU019491




expressed


—
D330027G24Rik

Mus musculus 13 days embryo heart
48
4.3
BB449568




cDNA, RIKEN full-length enriched library,




clone: D330027G24




product: unclassifiable, full insert




sequence


Mecp2
D630021H01Rik
methyl CpG binding protein 2
55
2.0
BB499491


D730019B10
D730019B10
hypothetical protein D730019B10
23
12.8
BB508669


Rpl30
D730044K07Rik
ribosomal protein L30
13
2.0
BB283415


D7Bwg0421e
D7Bwg0421e
DNA segment, Chr 7, Brigham &
31
8.1
BB667693




Women's Genetics 0421 expressed


D7Bwg0421e
D7Bwg0421e
DNA segment, Chr 7, Brigham &
59
8.4
AV370380




Women's Genetics 0421 expressed


Atp8a1
D830007B15Rik
ATPase, aminophospholipid transporter
124
2.7
BB303874




(APLT), class I, type 8A, member 1


Atp8a1
D830007B15Rik
ATPase, aminophospholipid transporter
164
4.3
BB303874




(APLT), class I, type 8A, member 1


Atp8a1
D830007B15Rik
ATPase, aminophospholipid transporter
184
5.6
AW610650




(APLT), class I, type 8A, member 1


Atp8a1
D830007B15Rik
ATPase, aminophospholipid transporter
150
2.9
BQ176779




(APLT), class I, type 8A, member 1


Atp8a1
D830007B15Rik
ATPase, aminophospholipid transporter
213
4.3
AW610650




(APLT), class I, type 8A, member 1


Dapp1
Dapp1
dual adaptor for phosphotyrosine and 3-
91
3.9
NM_011932




phosphoinositides 1


Dapp1
Dapp1
dual adaptor for phosphotyrosine and 3-
54
4.4
NM_011932




phosphoinositides 1


Dcamkl1
Dcamkl1
double cortin and calcium/calmodulin-
3
4.7
AW105916




dependent protein kinase-like 1


Dcamkl1
Dcamkl1
double cortin and calcium/calmodulin-
27
5.4
AW105916




dependent protein kinase-like 1


Dcamkl1
Dcamkl1
double cortin and calcium/calmodulin-
18
9.8
AW105916




dependent protein kinase-like 1


Dcamkl1
Dcamkl1
double cortin and calcium/calmodulin-
12
19.7
BB757120




dependent protein kinase-like 1


Dck
Dck
deoxycytidine kinase
54
5.3
BE630687


Dck
Dck
deoxycytidine kinase
103
12.6
BB030204


Dck
Dck
deoxycytidine kinase
105
5.1
NM_007832


Dcn
Dcn
decorin
2578
2.7
NM_007833


—
Ddef1

Mus musculus transcribed sequences
29
3.6
BG064109


Ddx21
Ddx21
DEAD (Asp-Glu-Ala-Asp) box polypeptide
293
2.1
BM246099




21


Ddx39
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide
940
2.6
BC020134




39


Ddx39
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide
1433
2.3
AV214253




39


6430573D20Rik
Ddx58
RIKEN cDNA 6430573D20 gene
505
3.9
BG063981


Def6
Def6
differentially expressed in FDCP 6
54
4.9
AK010356


5830484J08Rik
Depdc1a
RIKEN cDNA 5830484J08 gene
14
8.5
BC005799


—
Diap1

Mus musculus 7 days embryo whole
124
2.1
BB408240




body cDNA, RIKEN full-length enriched




library, clone: C430005H19




product: unknown EST, full insert




sequence


Dkk3
Dkk3
dickkopf homolog 3 (Xenopus laevis)
354
2.5
AK004853


Dkk3
Dkk3
dickkopf homolog 3 (Xenopus laevis)
293
2.3
AK004853


Hurp
Dlg7
hepatoma up-regulated protein
24
3.2
BB132734


Hurp
Dlg7
hepatoma up-regulated protein
34
4.5
BM250919


E130315B21Rik
Dna2l
RIKEN cDNA E130315B21 gene
363
2.0
BB546985


5330419I01Rik
Dnajc9
RIKEN cDNA 5330419I01 gene
626
2.1
BM942465


Dnase1l3
Dnase1l3
deoxyribonuclease 1-like 3
47
6.4
BC012671


Dnase1l3
Dnase1l3
deoxyribonuclease 1-like 3
12
8.8
BC012671


Npn1
Dnm3
neoplastic progression 1
86
2.5
BB542096


Dnmt1
Dnmt1
DNA methyltransferase (cytosine-5) 1
308
2.9
BB165431


—
Dock10

Mus musculus transcribed sequences
49
2.3
BB211894


Dock10
Dock10
dedicator of cytokinesis 10
17
3.0
BB763030


Dock10
Dock10
dedicator of cytokinesis 10
145
8.8
BF715043


—
Dock11

Mus musculus 11 days pregnant adult
106
11.1
AK017170




female ovary and uterus cDNA, RIKEN




full-length enriched library,




clone: 5033414A21 product: inferred:




human CLASP-4 {Homo sapiens}, full




insert sequence


Dok1
Dok1
downstream of tyrosine kinase 1
169
2.1
BC013066


Donson
Donson
downstream neighbor of SON
150
2.7
BQ174742


Dpt
Dpt
dermatopontin
246
2.4
NM_019759


Dpysl2
Dpysl2
dihydropyrimidinase-like 2
1968
2.0
BQ174209


—
Dpysl3

Mus musculus transcribed sequence with
78
3.7
AV161550




strong similarity to protein sp: Q14195




(H. sapiens) DPY3_HUMAN




Dihydropyrimidinase related protein-3




(DRP-3) (Unc-33-like phosphoprotein)




(ULIP protein) (Collapsin response




mediator protein 4) (CRMP-4)


Dsg2
Dsg2
desmoglein 2
693
2.1
BG092030


—
Dtx3l

Mus musculus transcribed sequence with
460
9.1
AV327407




weak similarity to protein




ref: NP_081764.1 (M. musculus) RIKEN




cDNA 5730493B19 [Mus musculus]


BC044798
Dtx4
cDNA sequence BC044798
589
2.5
AV017487


2610016C23Rik
Dufd1
RIKEN cDNA 2610016C23 gene
53
3.7
AK016786


Dusp10
Dusp10
dual specificity phosphatase 10
41
4.8
NM_022019


Dusp2
Dusp2
dual specificity phosphatase 2
54
5.0
L11330


Dutp
Dut
deoxyuridine triphosphatase
289
2.7
AF091101


—
E030018N11Rik

Mus musculus 0 day neonate lung cDNA,
314
3.4
BB794845




RIKEN full-length enriched library,




clone: E030018N11 product: hypothetical




protein, full insert sequence


E030024M05Rik
E030024M05Rik
RIKEN cDNA E030024M05 gene
259
2.1
BC025220


—
E130113K08Rik

Mus musculus transcribed sequences
31
4.5
BB491630


E130201N16Rik
E130201N16Rik
RIKEN cDNA E130201N16 gene
285
4.4
AJ132433


E2f1
E2f1
E2F transcription factor 1
80
2.3
AK017841


E2f2
E2f2
E2F transcription factor 2
22
4.3
BB543028


E2f7
E2f7
E2F transcription factor 7
33
3.5
BG069355


E330016A19Rik
E330016A19Rik
RIKEN cDNA E330016A19 gene
40
5.4
BB073366


E430004N04Rik
E430004N04Rik
RIKEN cDNA E430004N04 gene
65
7.1
BE628523


E430004N04Rik
E430004N04Rik
RIKEN cDNA E430004N04 gene
21
3.4
BB201286


E430019B13Rik
E430019B13Rik
RIKEN cDNA E430019B13 gene
51
2.2
BE630983


Ebi2
Ebi2
Epstein-Barr virus induced gene 2
51
4.5
BM242490


Ebi3
Ebi3
Epstein-Barr virus induced gene 3
70
2.9
NM_015766


Edg5
Edg5
endothelial differentiation, sphingolipid G-protein-
152
2.5
AK003144




coupled receptor, 5


Edg6
Edg6
endothelial differentiation, G-protein-
87
3.1
AV081616




coupled receptor 6


Ednra
Ednra
endothelin receptor type A
18
4.0
BC008277


D4Wsu27e
Efhd2
DNA segment, Chr 4, Wayne State
163
52.1
AA409309




University 27, expressed


Egr1
Egr1
early growth response 1
317
5.3
NM_007913


Egr2
Egr2
early growth response 2
3
19.6
X06746


Egr2
Egr2
early growth response 2
35
16.7
X06746


Egr3
Egr3
early growth response 3
27
10.5
AV346607


Eif1a
Eif1a
eukaryotic translation initiation factor 1A
923
2.3
BM200591


Eif1a
Eif1a
eukaryotic translation initiation factor 1A
1090
2.4
BM200591


1300018P11Rik
Eif4e3
RIKEN cDNA 1300018P11 gene
370
4.7
BC027014


1300018P11Rik
Eif4e3
RIKEN cDNA 1300018P11 gene
464
5.1
BC027014


Pctk2
Elk3
PCTAIRE-motif protein kinase 2
465
2.5
BM243464


Elk3
Elk3
ELK3, member of ETS oncogene family
425
2.0
BC005686


Elmo1
Elmo1
engulfment and cell motility 1, ced-12
36
3.4
NM_080288




homolog (C. elegans)


Elmo1
Elmo1
engulfment and cell motility 1, ced-12
79
3.7
BC024727




homolog (C. elegans)


Emb
Emb
embigin
402
2.3
BG064842


Emb
Emb
embigin
609
2.7
BG064842


Emilin1
Emilin1
elastin microfibril interface located protein 1
179
2.7
NM_133918


Emilin2
Emilin2
elastin microfibril interface located protein 2
92
3.8
BB811788


Emp1
Emp1
epithelial membrane protein 1
1072
2.0
U25633


Emp3
Emp3
epithelial membrane protein 3
299
5.4
BC001999


Emr1
Emr1
EGF-like module containing, mucin-like,
227
3.9
U66888




hormone receptor-like sequence 1


Emr4
Emr4
EGF-like module containing, mucin-like,
20
14.8
AF396935




hormone receptor-like sequence 4


Emr4
Emr4
EGF-like module containing, mucin-like,
27
10.3
AF396935




hormone receptor-like sequence 4


Enc1
Enc1
ectodermal-neural cortex 1
264
6.4
BM120053


Enc1
Enc1
ectodermal-neural cortex 1
175
4.0
BM120053


Enpp4
Enpp4
ectonucleotide
657
2.2
AV280361




pyrophosphatase/phosphodiesterase 4


Entpd1
Entpd1
ectonucleoside triphosphate
160
3.4
BI151440




diphosphohydrolase 1


Entpd1
Entpd1
ectonucleoside triphosphate
89
2.4
BI151440




diphosphohydrolase 1


Eomes
Eomes
eomesodermin homolog (Xenopus laevis)
69
2.1
BB128925


Epb4.1l2
Epb4.1l2
erythrocyte protein band 4.1-like 2
528
2.0
BE951907


Eppk1
Eppk1
epiplakin 1
74
2.1
BC026387


2310046K10Rik
Epsti1
RIKEN cDNA 2310046K10 gene
63
13.4
AK017174


2310046K10Rik
Epsti1
RIKEN cDNA 2310046K10 gene
106
14.2
BF020640


—
Espl1

Mus musculus 10 days neonate skin
91
2.7
BM200578




cDNA, RIKEN full-length enriched library,




clone: 4732457F20 product: unknown




EST, full insert sequence


Ets1
Ets1
E26 avian leukemia oncogene 1, 5′
82
2.6
BC010588




domain


Ets1
Ets1
E26 avian leukemia oncogene 1, 5′
564
3.2
BB151715




domain


Ets1
Ets1
E26 avian leukemia oncogene 1, 5′
556
5.1
BB151715




domain


Etv3
Etv3
ets variant gene 3
88
2.0
BM932547


—
Etv6

Mus musculus transcribed sequence with
73
2.4
BB735884




strong similarity to protein sp: P00722 (E. coli)




BGAL_ECOLI Beta-galactosidase




(Lactase)


Evi2a
Evi2a
ecotropic viral integration site 2a
54
7.7
BB236216


Evi2a
Evi2a
ecotropic viral integration site 2a
19
35.2
AI122415


Evl
Evl
Ena-vasodilator stimulated
96
2.5
AW546029




phosphoprotein


Evl
Evl
Ena-vasodilator stimulated
205
4.7
AW553781




phosphoprotein


Evl
Evl
Ena-vasodilator stimulated
159
3.7
NM_007965




phosphoprotein


Exo1
Exo1
exonuclease 1
65
2.4
BE986864


Exo1
Exo1
exonuclease 1
46
2.0
BE986864


2310032N20Rik
Exosc8
RIKEN cDNA 2310032N20 gene
433
3.7
AK009584


Ezh2
Ezh2
enhancer of zeste homolog 2
256
4.0
NM_007971




(Drosophila)


F10
F10
coagulation factor X
75
2.5
NM_007972


F13a
F13a1
coagulation factor XIII, alpha subunit
64
4.5
NM_028784


F2r
F2r
coagulation factor II (thrombin) receptor
1067
3.0
BQ173958


F2r
F2r
coagulation factor II (thrombin) receptor
2532
2.3
AV024285


F3
F3
coagulation factor III
542
2.8
BC024886


F730004D16Rik
F730004D16Rik
RIKEN cDNA F730004D16 gene
100
5.4
BM230330


—
F730047E07Rik

Mus musculus hypothetical LOC269515
37
4.7
BG071041




(LOC269515), mRNA


Fabp5
Fabp5
fatty acid binding protein 5, epidermal
504
3.0
BC002008


Fabp5
Fabp5
fatty acid binding protein 5, epidermal
150
3.5
BC002008


Fabp7
Fabp7
fatty acid binding protein 7, brain
795
5.2
NM_021272


Tnfrsf6
Fas
tumor necrosis factor receptor
120
6.0
NM_007987




superfamily, member 6


Fbn1
Fbn1
fibrillin 1
269
3.3
AF007248


Fbn1
Fbn1
fibrillin 1
494
3.0
NM_007993


Fbxo5
Fbxo5
F-box only protein 5
119
5.0
AK011820


Fbxo6b
Fbxo6b
F-box only protein 6b
455
3.0
NM_015797


1110064L07Rik
Fbxw17
RIKEN cDNA 1110064L07 gene
339
4.8
AV016303


Fcer1g
Fcer1g
Fc receptor, IgE, high affinity I, gamma
225
21.7
NM_010185




polypeptide


Fcgr1
Fcgr1
Fc receptor, IgG, high affinity I
123
4.8
BB075261


Fcgr1
Fcgr1
Fc receptor, IgG, high affinity I
74
21.0
AF143181


Fcgr2b
Fcgr3
Fc receptor, IgG, low affinity IIb
161
11.4
NM_010188


Fcrl3
Fcrl3
Fc receptor-like 3
114
20.5
BC027310


Fen1
Fen1
flap structure specific endonuclease 1
262
3.1
NM_007999


Fer1l3
Fer1l3
fer-1-like 3, myoferlin (C. elegans)
208
4.0
BI555209


Fes
Fes
feline sarcoma oncogene
105
3.0
BG867327


Fes
Fes
feline sarcoma oncogene
101
3.8
BG867327


Fga
Fga
fibrinogen, alpha polypeptide
605
6.1
BC005467


Fgd2
Fgd2
FYVE, RhoGEF and PH domain
109
2.2
NM_013710




containing 2


Fgd3
Fgd3
FYVE, RhoGEF and PH domain
66
2.7
AK018025




containing 3


1500031J01Rik
Fgfr1op2
RIKEN cDNA 1500031J01 gene
82
2.2
AB041650


Fgl2
Fgl2
fibrinogen-like protein 2
56
46.7
BF136544


Fgl2
Fgl2
fibrinogen-like protein 2
114
28.1
BF136544


Fgr
Fgr
Gardner-Rasheed feline sarcoma viral
120
5.4
NM_010208




(Fgr) oncogene homolog


Fgr
Fgr
Gardner-Rasheed feline sarcoma viral
105
4.3
BB165085




(Fgr) oncogene homolog


—
Fkbp10
—
84
2.3
AI325255


Fli1
Fli1
Friend leukemia integration 1
228
3.5
BB138212


Fli1
Fli1
Friend leukemia integration 1
75
5.1
NM_008026


1110008K06Rik
Fln29
RIKEN cDNA 1110008K06 gene
464
4.0
AK003586


5430425K04Rik
Fmnl2
RIKEN cDNA 5430425K04 gene
576
2.3
AK017338


Fnbp1
Fnbp1
formin binding protein 1
211
2.3
BM244005


Fos
Fos
FBJ osteosarcoma oncogene
119
9.1
AV026617


Fosl2
Fosl2
fos-like antigen 2
247
4.1
BM245170


Foxa1
Foxa1
forkhead box A1
46
2.3
NM_008259


Foxj1
Foxj1
forkhead box J1
53
2.1
L13204


Foxp1
Foxp1
forkhead box P1
120
2.2
BG962849


Fprl1
Fprl1
formyl peptide receptor-like 1
30
48.3
NM_008039


Frk
Frk
fyn-related kinase
193
2.2
BB787292


Fscn1
Fscn1
fascin homolog 1, actin bundling protein
820
3.1
NM_007984




(Strongylocentrotus) purpuratus)


Fshprh1
Fshprh1
FSH primary response 1
8
6.8
BB258991


Fstl1
Fstl1
follistatin-like 1
469
4.4
BI452727


Fstl1
Fstl1
follistatin-like 1
73
2.2
BB540658


Fstl1
Fstl1
follistatin-like 1
739
4.0
BI452727


Fthfsdc1
Fthfsdc1
formyltetrahydrofolate synthetase domain
145
3.2
AV095209




containing 1


Fus
Fus
fusion, derived from t(12; 16) malignant
1474
2.6
AF224264




liposarcoma (human)


Fut4
Fut4
fucosyltransferase 4
16
6.5
AV309809


Fxyd5
Fxyd5
FXYD domain-containing ion transport
491
7.4
NM_008761




regulator 5


Fyb
Fyb
FYN binding protein
73
3.8
BE853428


Fyb
Fyb
FYN binding protein
64
18.3
BM243379


Fyb
Fyb
FYN binding protein
70
19.2
BB157866


Fyn
Fyn
Fyn proto-oncogene
217
3.1
NM_008054


Fyn
Fyn
Fyn proto-oncogene
369
2.9
NM_008054


G430022H21Rik
G430022H21Rik
RIKEN cDNA G430022H21 gene
108
2.6
BM247306


G430041M01Rik
G430041M01Rik
RIKEN cDNA G430041M01 gene
602
2.1
BG069073


—
G430041M01Rik

Mus musculus adult male corpora
36
6.9
BM211445




quadrigemina cDNA, RIKEN full-length




enriched library, clone: B230214O09




product: unknown EST, full insert




sequence


Gab3
Gab3
growth factor receptor bound protein 2-
35
2.5
BB037935




associated protein 3


—
Gadd45b
—
152
2.5
AI323528


Galgt1
Galgt1
UDP-N-acetyl-alpha-D-galactosamine: (N-
99
8.2
U18975




acetylneuraminyl)-




galactosylglucosylceramide-beta-1, 4-N-




acetylgalactosaminyltransferase


Galnt12
Galnt12
UDP-N-acetyl-alpha-D-
92
2.6
AV376137




galactosamine: polypeptide N-




acetylgalactosaminyltransferase 12


Galnt6
Galnt6
UDP-N-acetyl-alpha-D-
7
11.2
AV231866




galactosamine: polypeptide N-




acetylgalactosaminyltransferase 6


—
Gas2l3

Mus musculus hypothetical LOC237436
59
3.3
BB770972




(LOC237436), mRNA


—
Gas2l3

Mus musculus hypothetical LOC237436
52
3.7
BB770972




(LOC237436), mRNA


Gas5
Gas5
growth arrest specific 5
2282
2.0
NM_013525


Gas5
Gas5
growth arrest specific 5
288
3.0
BI650268


Gas5
Gas5
growth arrest specific 5
121
5.2
AW547050


Gas5
Gas5
growth arrest specific 5
220
4.3
BC004622


Gbp1
Gbp1
guanylate nucleotide binding protein 1
9
54.5
NM_010259


Gbp2
Gbp2
guanylate nucleotide binding protein 2
272
53.4
BE197524


Gbp2
Gbp2
guanylate nucleotide binding protein 2
321
100.2
NM_010260


Gbp3
Gbp4
guanylate nucleotide binding protein 3
184
42.9
NM_018734


Gch
Gch1
GTP cyclohydrolase 1
54
3.3
NM_008102


Gcnt1
Gcnt1
glucosaminyl (N-acetyl) transferase 1,
26
6.9
AK017462




core 2


Gda
Gda
guanine deaminase
106
11.9
AW911807


Gda
Gda
guanine deaminase
33
5.4
NM_010266


Gda
Gda
guanine deaminase
81
12.1
AW911807


1110035O14Rik
Gdap10
RIKEN cDNA 1110035O14 gene
329
4.0
NM_010268


Gfpt1
Gfpt1
glutamine fructose-6-phosphate
74
2.7
AF334736




transaminase 1


Ggta1
Ggta1
glycoprotein galactosyltransferase alpha
42
3.2
M26925




1, 3


Ggta1
Ggta1
glycoprotein galactosyltransferase alpha
232
3.3
AF297615




1, 3


lan1
Gimap4
immune associated nucleotide 1
2439
3.0
BC005577


lan1
Gimap4
immune associated nucleotide 1
1384
2.4
BC005577


lan3
Gimap7
immune associated nucleotide 3
52
14.1
BC026200


lan3
Gimap7
immune associated nucleotide 3
9
7.7
BB223831


—
Gimap8

Mus musculus similar to hypothetical
716
3.2
BM243674




protein (LOC243374), mRNA


—
Gimap8
—
22
7.8
BB236014


Glipr1
Glipr1
GLI pathogenesis-related 1 (glioma)
144
14.8
BC025083


Glipr2
Glipr2
GLI pathogenesis-related 2
36
12.8
BM208214


Glipr2
Glipr2
GLI pathogenesis-related 2
49
8.2
BM208214


—
Gls

Mus musculus transcribed sequences
190
2.7
BM239869


Gmfg
Gmfg
glia maturation factor, gamma
310
5.7
NM_022024


Gmfg
Gmfg
glia maturation factor, gamma
76
5.9
NM_022024


—
Gna13

Mus musculus transcribed sequences
227
2.0
BI180797


Gna13
Gna13
guanine nucleotide binding protein, alpha
1712
2.7
BG073165




13


Gnb4
Gnb4
guanine nucleotide binding protein, beta 4
290
2.1
BI713933


Gnb4
Gnb4
guanine nucleotide binding protein, beta 4
204
3.4
BI713933


Gng10
Gng10
guanine nucleotide binding protein (G
619
2.4
NM_025277




protein), gamma 10


—
Gng2

Mus musculus 15 days embryo male
224
2.3
AV021455




testis cDNA, RIKEN full-length enriched




library, clone: 8030491K24




product: unknown EST, full insert




sequence


Gng2
Gng2
guanine nucleotide binding protein (G
91
7.8
BB522409




protein), gamma 2 subunit


—
Gng2

Mus musculus 15 days embryo male
111
2.6
AV021455




testis cDNA, RIKEN full-length enriched




library, clone: 8030491K24




product: unknown EST, full insert




sequence


Gp38
Gp38
glycoprotein 38
383
2.6
NM_010329


Gpm6b
Gpm6b
glycoprotein m6b
249
3.0
AF254879


Gpm6b
Gpm6b
glycoprotein m6b
232
4.4
AK016567


Gpr132
Gpr132
G protein-coupled receptor 132
47
3.8
BB208670


F730001G15Rik
Gpr171
RIKEN cDNA F730001G15 gene
17
17.5
BB229616


Gpr18
Gpr18
G protein-coupled receptor 18
100
9.9
BG145550


Gpr35
Gpr35
G protein-coupled receptor 35
15
14.0
NM_022320


Gpr43
Gpr43
G protein-coupled receptor 43
17
2.6
AV370830


Gpr64
Gpr64
G protein-coupled receptor 64
79
2.2
AV242919


Gpcr25
Gpr65
G-protein coupled receptor 25
50
13.6
NM_008152


Gpr68
Gpr68
G protein-coupled receptor 68
24
10.0
BB538372


Gpr84
Gpr84
G protein-coupled receptor 84
18
17.9
NM_030720


Gprk6
Gprk6
G protein-coupled receptor kinase 6
556
2.5
BB461269


Gprk6
Gprk6
G protein-coupled receptor kinase 6
299
2.1
AF040748


1810036L03Rik
Gsdmdc1
RIKEN cDNA 1810036L03 gene
133
6.5
AK007710


Gsg2
Gsg2
germ cell-specific gene 2
34
3.1
BE457839


Gzma
Gzma
granzyme A
68
14.1
NM_010370


Gzmk
Gzmk
granzyme K
24
14.1
AB032200


H28
H28
histocompatibility 28
343
8.9
NM_031367


H28
H28
histocompatibility 28
370
6.8
BC024930


H2-Aa
H2-Aa
histocompatibility 2, class II antigen A,
1265
12.3
AV018723




alpha


H2-Aa
H2-Aa
histocompatibility 2, class II antigen A,
3501
7.1
BE688749




alpha


—
H2-Aa
—
18
46.1
AV086906


H2-Aa
H2-Aa
histocompatibility 2, class II antigen A,
2137
10.8
AF119253




alpha


H2-Ab1
H2-Ab1
histocompatibility 2, class II antigen A,
421
19.9
M15848




beta 1


H2-Ab1
H2-Ab1
histocompatibility 2, class II antigen A,
950
13.2
NM_010379




beta 1


H2-Ab1
H2-Ab1
histocompatibility 2, class II antigen A,
659
18.5
M15848




beta 1


H2afx
H2afx
H2A histone family, member X
654
2.0
NM_010436


H2-D1
H2-D1
histocompatibility 2, D region locus 1
87
3.5
X00246


H2-D1
H2-D1
histocompatibility 2, D region locus 1
76
34.3
M34962


H2-D1
H2-D1
histocompatibility 2, D region locus 1
43
15.6
M33151


H2-D1
H2-D1
histocompatibility 2, D region locus 1
437
26.3
M86502


H2-D1
H2-D1
histocompatibility 2, D region locus 1
43
11.3
M83244


H2-D1
H2-D1
histocompatibility 2, D region locus 1
2224
6.2
NM_010380


H2-D1
H2-D1
histocompatibility 2, D region locus 1
228
52.6
L36068


H2-D1
H2-D1
histocompatibility 2, D region locus 1
152
50.7
M69068


—
H2-DMa
—
6
16.9
BB425495


H2-DMa
H2-DMa
histocompatibility 2, class II, locus DMa
261
20.9
NM_010386


H2-DMb1
H2-DMb1
histocompatibility 2, class II, locus Mb1
121
38.0
NM_010388


H2-DMb1
H2-DMb1
histocompatibility 2, class II, locus Mb1
159
45.2
BB734586


H2-DMb1
H2-DMb1
histocompatibility 2, class II, locus Mb1
347
16.8
NM_010388


H2-DMb1
H2-DMb1
histocompatibility 2, class II, locus Mb1
116
19.8
NM_010387


H2-DMb1
H2-DMb1
histocompatibility 2, class II, locus Mb1
87
53.8
BB734586


H2-Ea
H2-Ea
histocompatibility 2, class II antigen E
103
3.7
U13648




alpha


H2-Ea
H2-Ea
histocompatibility 2, class II antigen E
63
6.4
U13648




alpha


H2-Eb1
H2-Eb1
histocompatibility 2, class II antigen E
1760
8.6
NM_010382




beta


H2-K
H2-K
histocompatibility 2, K region
136
5.9
J00406


H2-K
H2-K1
histocompatibility 2, K region
626
22.5
L23495


—
H2-K1
MHC l = H-2Kd homolog {alternatively
435
45.5
S70184




spliced, deletion of exon 3} [mice, DBA/2,




L1210 lymphoma, mRNA Mutant, 855 nt]


H2-K
H2-K1
histocompatibility 2, K region
606
23.9
BC011306


H2-M3
H2-M3
histocompatibility 2, M region locus 3
261
4.8
NM_013819


H2-Oa
H2-Oa
histocompatibility 2, O region alpha locus
56
6.1
NM_008206


H2-Ob
H2-Ob
histocompatibility 2, O region beta locus
38
4.4
BG144448


H2-Q1
H2-Q1
histocompatibility 2, Q region locus 1
125
3.7
M58156


H2-Q1
H2-Q1
histocompatibility 2, Q region locus 1
35
22.6
BC010602


H2-K
H2-Q5
histocompatibility 2, K region
20
18.3
NM_010393


H2-Q7
H2-Q7
histocompatibility 2, Q region locus 7
20
14.9
AK013097


H2-Q7
H2-Q7
histocompatibility 2, Q region locus 7
37
78.5
M29881


H2-T10
H2-T10
histocompatibility 2, T region locus 10
2355
4.3
NM_010395


H2-T23
H2-T23
histocompatibility 2, T region locus 23
2198
8.0
NM_010398


—
H2-T23

Mus musculus 2 days neonate thymus
71
6.6
NM_010398




thymic cells cDNA, RIKEN full-length




enriched library, clone: C920026N01




product: weakly similar to H-2 CLASS I




HISTOCOMPATIBILITY ANTIGEN, D-37




ALPHA CHAIN PRECURSOR [Mus





musculus], full insert sequence


H2-T24
H2-T24
histocompatibility 2, T region locus 24
109
3.1
L22338


Has2
Has2
hyaluronan synthase 2
37
2.5
NM_008216


Havcr1
Havcr1
hepatitis A virus cellular receptor 1
700
7.0
NM_134248


Havcr1
Havcr1
hepatitis A virus cellular receptor 1
1015
7.8
BM211416


Havcr2
Havcr2
hepatitis A virus cellular receptor 2
39
4.7
AF450241


—
Hck

Mus musculus transcribed sequences
28
2.2
BM246401


Hck
Hck
hemopoietic cell kinase
117
17.9
NM_010407


Hcph
Hcph
hemopoietic cell phosphatase
617
4.1
NM_013545


Hells
Hells
helicase, lymphoid specific
65
10.4
NM_008234


4930568P13Rik
Hemp1
RIKEN cDNA 4930568P13 gene
36
25.3
BM238906


4930568P13Rik
Hemp1
RIKEN cDNA 4930568P13 gene
147
4.8
BM238906


2510038N07Rik
Herc5
RIKEN cDNA 2510038N07 gene
217
12.8
AI639807


2510038N07Rik
Herc5
RIKEN cDNA 2510038N07 gene
64
18.0
AK015214


2510038N07Rik
Herc5
RIKEN cDNA 2510038N07 gene
161
25.4
AW208668


2510038N07Rik
Herc5
RIKEN cDNA 2510038N07 gene
72
20.4
AI639807


Hesx1
Hesx1
homeo box gene expressed in ES cells
76
4.2
NM_010420


Hgf
Hgf
hepatocyte growth factor
74
2.7
D10212


Hgf
Hgf
hepatocyte growth factor
49
3.0
AF042856


Hgf
Hgf
hepatocyte growth factor
37
2.8
BB476818


—
Hif1a

Mus musculus transcribed sequences
10
3.9
BB409314


Hist1h2ae
Hist1h2ae
histone 1, H2ae
525
24.6
W91024


Hivep2
Hivep2
human immunodeficiency virus type I
138
2.0
AW321867




enhancer binding protein 2


Hk2
Hk2
hexokinase 2
79
7.1
NM_013820


Hk3
Hk3
hexokinase 3
106
6.7
BB334625


—
Hk3
—
97
14.9
BB324660


Hmgb2
Hmgb2
high mobility group box 2
544
7.3
X67668


Hmgb2
Hmgb2
high mobility group box 2
337
9.1
C85885


Hn1
Hn1
hematological and neurological
327
4.3
NM_008258




expressed sequence 1


Hn1
Hn1
hematological and neurological
236
5.6
NM_008258




expressed sequence 1


—
Hnrpa1

Mus musculus transcribed sequence with
705
3.1
BI663320




strong similarity to protein




ref: NP_002127.1 (H. sapiens)




heterogeneous nuclear ribonucleoprotein




A1, isoform a; nuclear ribonucleoprotein




particle A1 protein; helix-destabilizing




protein; single-strand DNA-binding




protein UP1; heterogeneous nuclear




ribonucleoprotein core protein A1;




heterogeneous nuclear ribonucleoprotein




A1B protein; heterogeneous nuclear




ribonucleoprotein B2 protein [Homo





sapiens]


Hnrpa1
Hnrpa1; Hdp;
heterogeneous nuclear ribonucleoprotein
1077
2.1
AK007802



hnrnp-A1;
A1



D15Ertd119e


2610510D13Rik
Hnrpa3
RIKEN cDNA 2610510D13 gene
2441
2.0
BC024454


Hnrpdl
Hnrpdl
heterogeneous nuclear ribonucleoprotein
787
2.3
NM_016690




D-like


Hp
Hp
haptoglobin
53
9.9
NM_017370


Hpse
Hpse
heparanase
32
22.8
BG094050


Hrasls3
Hrasls3
HRAS like suppressor 3
504
16.5
BC024581


Hrb
Hrb
HIV-1 Rev binding protein
4
2.5
BG068396


4930534K13Rik
Ibrdc3
RIKEN cDNA 4930534K13 gene
280
7.3
AK015966


4930534K13Rik
Ibrdc3
RIKEN cDNA 4930534K13 gene
430
6.2
BG064140


Icam1
Icam1
intercellular adhesion molecule
440
10.2
BC008626


Icos
Icos
inducible T-cell co-stimulator
68
9.8
AV313923


Icsbp1
Icsbp1
interferon consensus sequence binding
228
9.9
BG069095




protein 1


Icsbp1
Icsbp1
interferon consensus sequence binding
432
10.0
BG069095




protein 1


Ier5
Ier5
immediate early response 5
347
3.1
BF147705


Ifi1
Ifi1
interferon inducible protein 1
1151
15.4
NM_008326


Ifi202b
Ifi202b
interferon activated gene 202B
118
46.5
NM_011940


Ifi202b
Ifi202b
interferon activated gene 202B
93
42.5
AV229143


Ifi203
Ifi203
interferon activated gene 203
63
17.8
NM_008328


Ifi203
Ifi203
interferon activated gene 203
177
9.1
BC008167


Ifi16
Ifi204
interferon, gamma-inducible protein 16
22
24.8
NM_008329


Ifi205
Ifi205
interferon activated gene 205
12
140.4
M74124


Ifi205
Ifi205
interferon activated gene 205
30
151.7
M74124


Ifi205
Ifi205
interferon activated gene 205
38
79.7
AI481797


Ifi205
Ifi205
interferon activated gene 205
76
102.7
AI481797


2310061N23Rik
Ifi27
RIKEN cDNA 2310061N23 gene
219
8.2
AY090098


Ifi30
Ifi30
interferon gamma inducible protein 30
3381
2.4
NM_023065


2010008K16Rik
Ifi35
RIKEN cDNA 2010008K16 gene
1277
6.0
AW986054


2010008K16Rik
Ifi35
RIKEN cDNA 2010008K16 gene
377
4.5
BC008158


2010008K16Rik
Ifi35
RIKEN cDNA 2010008K16 gene
371
2.5
AW986054


A430056A10Rik
Ifi44
RIKEN cDNA A430056A10 gene
439
5.0
BB329808


9130009C22Rik
Ifih1
RIKEN cDNA 9130009C22 gene
506
5.4
AY075132


Ifit1
Ifit1
interferon-induced protein with
93
18.5
NM_008331




tetratricopeptide repeats 1


Ifit2
Ifit2
interferon-induced protein with
271
33.8
NM_008332




tetratricopeptide repeats 2


Ifit3
Ifit3
interferon-induced protein with
761
6.3
NM_010501




tetratricopeptide repeats 3


1110036C17Rik
Ifitm1
RIKEN cDNA 1110036C17 gene
622
4.0
BC027285


1110004C05Rik
Ifitm3
RIKEN cDNA 1110004C05 gene
3701
4.2
BC010291


A330075D07
Ifitm6
hypothetical protein A330075D07
34
10.6
BB193024


Ifnar2
Ifnar2
interferon (alpha and beta) receptor 2
107
3.0
Y09864


Ifnar2
Ifnar2
interferon (alpha and beta) receptor 2
155
2.7
BB522265


Ifnar2
Ifnar2
interferon (alpha and beta) receptor 2
977
2.4
AF013486


Ifng
Ifng
interferon gamma
32
30.3
K00083


Ifngr
Ifngr1
interferon gamma receptor
572
2.0
NM_010511


Ifrd1
Ifrd1
interferon-related developmental
463
3.0
NM_013562




regulator 1


Igf1
Igf1
insulin-like growth factor 1
606
2.0
BG075165


Igf1
Igf1
insulin-like growth factor 1
184
2.7
NM_010512


Igf1
Igf1
insulin-like growth factor 1
236
2.2
AF440694


Igf1
Igf1
insulin-like growth factor 1
398
3.1
BG092677


Igh-6
Igh-6
immunoglobulin heavy chain 6 (heavy
140
12.8
BB226392




chain of IgM)


Igh-6
Igh-6
immunoglobulin heavy chain 6 (heavy
269
6.0
AI326478




chain of IgM)


Igsf6
Igsf6
immunoglobulin superfamily, member 6
8
25.4
NM_030691


Igsf7
Igsf7
immunoglobulin superfamily, member 7
101
7.0
AF251705


—
Igtp

Mus musculus 13 days embryo lung
35
14.3
BB485297




cDNA, RIKEN full-length enriched library,




clone: D430030N05 product: unknown




EST, full insert sequence


Igtp
Igtp
interferon gamma induced GTPase
905
25.9
NM_018738


AI481100
Igtp
expressed sequence AI481100
365
30.9
NM_019440


Ii
Ii
Ia-associated invariant chain
3790
6.2
BC003476


AW111922
Iigp1
expressed sequence AW111922
885
36.6
BM239828


AW111922
Iigp1
expressed sequence AW111922
361
53.7
BM239828


Il11
Il11
interleukin 11
43
4.4
NM_008350


Il12b
Il12b
interleukin 12b
29
4.2
AF128214


Il12rb1
Il12rb1
interleukin 12 receptor, beta 1
35
5.5
NM_008353


Il18
Il18
interleukin 18
330
2.1
NM_008360


Il18bp
Il18bp
interleukin 18 binding protein
122
33.6
AF110803


Il18rap
Il18rap
interleukin 18 receptor accessory protein
12
8.4
NM_010553


Il1b
Il1b
interleukin 1 beta
118
4.7
BC011437


Il1rn
Il1rn
interleukin 1 receptor antagonist
40
14.3
M57525


Il1rn
Il1rn
interleukin 1 receptor antagonist
99
6.6
NM_031167


Tccr
Il27ra
T cell cytokine receptor
28
8.2
NM_016671


Il2rb
Il2rb
interleukin 2 receptor, beta chain
39
12.3
BE634648


Il4i1
Il4i1
interleukin 4 induced 1
46
3.9
NM_010215


Il4ra
Il4ra
interleukin 4 receptor, alpha
203
2.8
NM_010557


Il6
Il6
interleukin 6
15
20.8
NM_031168


Il7r
Il7r
interleukin 7 receptor
72
4.6
AI573431


Incenp
Incenp
inner centromere protein
80
4.4
BI410774


Incenp
Incenp
inner centromere protein
192
9.0
BB418702


Indo
Indo
indoleamine-pyrrole 2,3 dioxygenase
15
6.7
NM_008324


Inhbb
Inhbb
inhibin beta-B
98
4.2
BB253137


Inpp5d
Inpp5d
inositol polyphosphate-5-phosphatase D
170
4.7
U39203


Irak3
Irak3
interleukin-1 receptor-associated kinase 3
43
2.8
AV228493


Irak4
Irak4
interleukin-1 receptor-associated kinase 4
63
3.2
BM220651


B430217B02Rik
Irf1
RIKEN cDNA B430217B02 gene
665
15.7
NM_008390


—
Irf2
—
53
4.9
AI606908


Irf5
Irf5
interferon regulatory factor 5
205
2.7
NM_012057


Irf7
Irf7
interferon regulatory factor 7
198
9.8
NM_016850


Irg1
Irg1
immunoresponsive gene 1
9
80.3
L38281


Isg20
Isg20
interferon-stimulated protein
119
4.7
BC022751


Isgf3g
Isgf3g
interferon dependent positive acting
327
3.6
NM_008394




transcription factor 3 gamma


Itga4
Itga4
integrin alpha 4
45
4.4
BB284583


Itga4
Itga4
integrin alpha 4
19
8.5
NM_010576


—
Itga4

Mus musculus adult retina cDNA, RIKEN
138
7.9
BB205589




full-length enriched library,




clone: A930029I05 product: unknown EST,




full insert sequence


Itgal
Itgal
integrin alpha L
118
9.3
BI554446


Itgam
Itgam
integrin alpha M
16
12.4
NM_008401


Itgax
Itgax
integrin alpha X
80
11.9
NM_021334


Itgb2
Itgb2
integrin beta 2
178
28.7
NM_008404


Jak2
Jak2
Janus kinase 2
882
2.4
NM_008413


Jak2
Jak2
Janus kinase 2
353
3.1
NM_008413


Smcx
Jarid1c
selected mouse cDNA on the X
35
2.1
BB165753


Jun
Jun
Jun oncogene
559
2.7
NM_010591


Kcnab2
Kcnab2
potassium voltage-gated channel,
35
9.0
U31908




shaker-related subfamily, beta member 2


D7Ertd764e
Kcnk6
DNA segment, Chr 7, ERATO Doi 764,
139
3.5
BG069589




expressed


Kcnn4
Kcnn4
potassium intermediate/small
45
28.2
BG865910




conductance calcium-activated channel,




subfamily N, member 4


—
Kcnq5

Mus musculus transcribed sequences
17
2.9
BB162318


Khdrbs1
Khdrbs1
KH domain containing, RNA binding,
290
7.1
BB752997




signal transduction associated 1


Kif11
Kif11
kinesin family member 11
41
6.6
BB827235


—
Kif11

Mus musculus transcribed sequences
68
5.0
BM234447


Kif11
Kif11
kinesin family member 11
89
4.5
B8827235


Kif18a
Kif18a
kinesin family member 18A
63
2.8
BC016095


Kif20a
Kif20a
kinesin family member 20A
65
4.3
NM_009004


Kif21b
Kif21b
kinesin family member 21B
113
3.2
AV122249


Kif22
Kif22
kinesin family member 22
248
8.4
BB251322


Kif2c
Kif2c
kinesin family member 2C
43
8.7
BB104669


Kif2c
Kif2c
kinesin family member 2C
74
4.4
NM_134471


Kif4
Kif4
kinesin family member 4
71
3.2
NM_008446


Klf5
Klf5
Kruppel-like factor 5
164
2.4
BG069607


KLHL6
Klhl6
kelch-like 6
297
3.1
BM247104


Klra2
Klra2
killer cell lectin-like receptor, subfamily A,
30
14.3
NM_008462




member 2


Klra7
Klra7
killer cell lectin-like receptor, subfamily A,
7
7.9
U10095




member 7


Klra8
Klra8
killer cell lectin-like receptor, subfamily A,
17
5.5
U12889




member 8


Klra3
Klra9
killer cell lectin-like receptor, subfamily A,
68
6.5
U49865




member 3


Klrb1d
Klrb1d
killer cell lectin-like receptor subfamily B
11
4.2
AF342896




member 1D


Klrb1d
Klrb1d
killer cell lectin-like receptor subfamily B
25
4.6
AF342896




member 1D


Klrb1d
Klrb1d
killer cell lectin-like receptor subfamily B
20
9.8
NM_008526




member 1D


Klrb1d
Klrb1d
killer cell lectin-like receptor subfamily B
17
10.2
AV294178




member 1D


Klrc1
Klrc1
killer cell lectin-like receptor subfamily C,
6
19.3
AF106009




member 1


Klre1
Klre1
killer cell lectin-like receptor family E
33
3.2
BG230222




member 1


Klrk1
Klrk1
killer cell lectin-like receptor subfamily K,
66
21.5
AF039026




member 1


Kntc1
Kntc1
kinetochore associated 1
71
4.4
AW536884


Kpna2
Kpna2
karyopherin (importin) alpha 2
1340
2.6
NM_010655


Kpna3
Kpna3
karyopherin (importin) alpha 3
449
2.0
BM213828


Kpnb1
Kpnb1
karyopherin (importin) beta 1
1298
3.3
BC004096


9030623C06Rik
Krt20
RIKEN cDNA 9030623C06 gene
37
4.4
AF473907


Laf4
Laf4
lymphoid nuclear protein related to AF4
37
4.3
BQ177036


D7Bwg0421e
Lair1
DNA segment, Chr 7, Brigham &
64
11.9
AK017222




Women's Genetics 0421 expressed


Laptm5
Laptm5
lysosomal-associated protein
31
4.5
BB264849




transmembrane 5


Laptm5
Laptm5
lysosomal-associated protein
173
30.9
BB218107




transmembrane 5


—
Lass6

Mus musculus adult male small intestine
57
2.3
BG072448




cDNA, RIKEN full-length enriched library,




clone: 2010109K09




product: unclassifiable, full insert




sequence


Lbp
Lbp
lipopolysaccharide binding protein
175
3.3
NM_008489


Lck
Lck
lymphocyte protein tyrosine kinase
6
3.5
AA867167


Lck
Lck
lymphocyte protein tyrosine kinase
23
2.2
BB200032


Lck
Lck
lymphocyte protein tyrosine kinase
93
9.2
AA867167


Lck
Lck
lymphocyte protein tyrosine kinase
128
19.5
BC011474


Lcn2
Lcn2
lipocalin 2
176
29.2
X14607


Lcp1
Lcp1
lymphocyte cytosolic protein 1
231
20.8
NM_008879


Lcp1
Lcp1
lymphocyte cytosolic protein 1
515
15.0
NM_008879


Lcp2
Lcp2
lymphocyte cytosolic protein 2
48
31.8
BC006948


Lfng
Lfng
lunatic fringe gene homolog (Drosophila)
146
3.0
NM_008494


Lgals1
Lgals1
lectin, galactose binding, soluble 1
5227
2.9
AI642438


Lgals1
Lgals1
lectin, galactose binding, soluble 1
3962
2.8
NM_008495


—
Lgals3

Mus musculus transcribed sequences
44
2.8
AI426376


Lgals3
Lgals3
lectin, galactose binding, soluble 3
2066
3.2
X16834


Ppicap
Lgals3bp
peptidylprolyl isomerase C-associated
1079
4.7
NM_011150




protein


Lig1
Lig1
ligase I, DNA, ATP-dependent
193
3.6
NM_010715


Gp49b
Lilrb4
glycoprotein 49 B
133
22.1
U05264


Litaf
Litaf
LPS-induced TN factor
814
3.7
AV360881


Litaf
Litaf
LPS-induced TN factor
1740
4.3
AV360881


LOC207685
LOC207685
hypothetical protein LOC207685
66
5.0
AK008551


LOC207685
LOC207685
hypothetical protein LOC207685
109
2.7
AK008551


LOC209387
LOC209387
tripartite motif protein 30-like
81
9.7
BG068242


LOC209387
LOC209387
tripartite motif protein 30-like
15
20.2
BM241342


LOC223672
LOC223672
hypothetical protein LOC223672
18
25.0
BC020489


5830475I06Rik
Loh11cr2a
RIKEN cDNA 5830475I06 gene
588
4.9
BC004727


Lox
Lox
lysyl oxidase
87
7.5
M65143


Lox
Lox
lysyl oxidase
154
7.4
M65143


Loxl3
Loxl3
lysyl oxidase-like 3
121
3.5
NM_013586


4832412D13Rik
Lrch1
RIKEN cDNA 4832412D13 gene
241
2.2
BB755336


—
Lrch1

Mus musculus transcribed sequences
22
5.8
AW909485


1300008B03Rik
Lrg1
RIKEN cDNA 1300008B03 gene
81
3.7
NM_029796


Lrmp
Lrmp
lymphoid-restricted membrane protein
72
6.9
NM_008511


Lrp1
Lrp1
low density lipoprotein receptor-related
38
2.1
AV345706




protein 1


Lrrfip1
Lrrfip1
leucine rich repeat (in FLII) interacting
837
3.0
BG069059




protein 1


AW319595
Lrrk1
expressed sequence AW319595
233
2.3
BC027199


Lsm5
Lsm5
LSM5 homolog, U6 small nuclear RNA
457
2.3
NM_025520




associated (S. cerevisiae)


Lsp1
Lsp1
lymphocyte specific 1
199
8.8
NM_019391


Lst1
Lst1
leukocyte specific transcript 1
98
18.7
U72644


Lta
Lta
lymphotoxin A
7
5.8
NM_010735


Ltbp2
Ltbp2
latent transforming growth factor beta
35
14.9
NM_013589




binding protein 2


Ly6c
Ly6c
lymphocyte antigen 6 complex, locus C
3983
2.8
NM_010741


Ly6e
Ly6e
lymphocyte antigen 6 complex, locus E
1793
6.8
BM245572


Ly6f
Ly6f
lymphocyte antigen 6 complex, locus F
24
4.3
NM_008530


Ly6i
Ly6i
lymphocyte antigen 6 complex, locus I
189
15.4
AF232024


Ly78
Ly78
lymphocyte antigen 78
77
3.2
NM_008533


Ly86
Ly86
lymphocyte antigen 86
165
24.1
NM_010745


Lyn
Lyn
Yamaguchi sarcoma viral (v-yes-1)
275
3.6
M64608




oncogene homolog


Lyn
Lyn
Yamaguchi sarcoma viral (v-yes-1)
585
2.9
M57697




oncogene homolog


Lyst
Lyst
lysosomal trafficking regulator
347
2.0
BB463428


Lyzs
Lyzs
lysozyme
483
27.0
AW208566


Lyzs
Lyzs
lysozyme
327
56.6
AV058500


—
Lztfl1

Mus musculus transcribed sequence with
1043
2.1
BF320908




strong similarity to protein




ref: NP_002127.1 (H. sapiens)




heterogeneous nuclear ribonucleoprotein




A1, isoform a; nuclear ribonucleoprotein




particle A1 protein; helix-destabilizing




protein; single-strand DNA-binding




protein UP1; heterogeneous nuclear




ribonucleoprotein core protein A1;




heterogeneous nuclear ribonucleoprotein




A1B protein; heterogeneous nuclear




ribonucleoprotein B2 protein [Homo





sapiens]


Mad
Mad
Max dimerization protein
110
2.8
AV228517


Mad
Mad
Max dimerization protein
204
2.1
AV228517


Mad2l1
Mad2l1
MAD2 (mitotic arrest deficient, homolog)-
349
3.8
NM_019499




like 1 (yeast)


Mafb
Mafb
v-maf musculoaponeurotic fibrosarcoma
24
2.5
AW412521




oncogene family, protein B (avian)


Maff
Maff
v-maf musculoaponeurotic fibrosarcoma
91
2.7
BC022952




oncogene family, protein F (avian)


Map3k1
Map3k1
mitogen activated protein kinase kinase
319
2.4
L13103




kinase 1


Map4k1
Map4k1
mitogen activated protein kinase kinase
17
13.9
BB546619




kinase kinase 1


Marcks
Marcks
myristoylated alanine rich protein kinase
1601
2.1
AW546141




C substrate


Marcks
Marcks
myristoylated alanine rich protein kinase
847
2.4
AW546141




C substrate


Marcks
Marcks
myristoylated alanine rich protein kinase
1166
2.5
BB100920




C substrate


Mbc2
Mbc2
membrane bound C2 domain containing
279
4.2
BC011482




protein


—
Mbnl1

Mus musculus transcribed sequences
96
3.8
BM201095


—
Mbnl3

Mus musculus 0 day neonate lung cDNA,
104
4.0
AV306759




RIKEN full-length enriched library,




clone: E030002K20 product: similar to




MUSCLEBLIND-LIKE PROTEIN




FLJ11316/DKFZP434G2222/DJ842K24.1




[Homo sapiens], full insert sequence


Mbtps2
Mbtps2
RIKEmembrane-bound transcription
46
4.0
AV272026




factor protease, site 2


Mcl1
Mcl1
myeloid cell leukemia sequence 1
3111
2.4
BB374534


Mcl1
Mcl1
myeloid cell leukemia sequence 1
1844
2.4
BC003839


Mcm2
Mcm2
minichromosome maintenance deficient 2
257
3.3
NM_008564




mitotin (S. cerevisiae)


Mcm3
Mcm3
minichromosome maintenance deficient 3
115
5.2
C80350




(S. cerevisiae)


Mcm3
Mcm3
minichromosome maintenance deficient 3
23
15.8
BI658327




(S. cerevisiae)


Mcm3
Mcm3
minichromosome maintenance deficient 3
199
5.7
C80350




(S. cerevisiae)


Mcm3
Mcm3
minichromosome maintenance deficient 3
39
3.2
C80350




(S. cerevisiae)


Mcm3
Mcm3
minichromosome maintenance deficient 3
60
9.2
BI658327




(S. cerevisiae)


Mcm4
Mcm4
minichromosome maintenance deficient 4
211
4.5
BB447978




homolog (S. cerevisiae)


Mcm4
Mcm4
minichromosome maintenance deficient 4
356
4.1
BC013094




homolog (S. cerevisiae)


Mcm5
Mcm5
minichromosome maintenance deficient
260
9.4
AI324988




5, cell division cycle 46 (S. cerevisiae)


Mcm5
Mcm5
minichromosome maintenance deficient
160
6.2
NM_008566




5, cell division cycle 46 (S. cerevisiae)


Mcm6
Mcm6
minichromosome maintenance deficient 6
304
3.7
BB099487




(MIS5 homolog, S. pombe) (S. cerevisiae)


—
Mcm7

Mus musculus adult male thymus cDNA,
766
2.0
NM_008568




RIKEN full-length enriched library,




clone: 5830410A10 product: minichromosome




maintenance deficient 7 (S. cerevisiae),




full insert sequence


—
Mcm7

Mus musculus adult male thymus cDNA,
267
2.7
BB407228




RIKEN full-length enriched library,




clone: 5830410A10 product: minichromosome




maintenance deficient 7 (S. cerevisiae),




full insert sequence


—
Mcm7

Mus musculus adult male thymus cDNA,
1385
2.3
BB464359




RIKEN full-length enriched library,




clone: 5830410A10 product: minichromosome




maintenance deficient 7 (S. cerevisiae),




full insert sequence


Kdt1
Mdfid
kidney cell line derived transcript 1
889
2.2
U13371


Me2
Me2
malic enzyme 2, NAD(+)-dependent,
51
3.4
BM235734




mitochondrial


Me2
Me2
malic enzyme 2, NAD(+)-dependent,
129
4.1
BM235734




mitochondrial


Mefv
Mefv
Mediterranean fever
140
3.7
NM_019453


—
Metap2

Mus musculus transcribed sequences
44
2.1
BM730703


Mfap5
Mfap5
microfibrillar associated protein 5
43
3.7
NM_015776


Mfap5
Mfap5
microfibrillar associated protein 5
67
7.2
NM_015776


—
MGC58382

Mus musculus cDNA clone MGC: 58382
58
14.2
BG961961




IMAGE: 6774154, complete cds


1200016D23Rik
MGC65590
RIKEN cDNA 1200016D23 gene
5
2.8
BB093351


Mgl1
Mgl1
macrophage galactose N-acetyl-
35
4.5
NM_010796




galactosamine specific lectin 1


Mglap
Mglap
matrix gamma-carboxyglutamate (gla)
4867
2.3
NM_008597




protein


Mki67
Mki67
antigen identified by monoclonal antibody
129
11.7
X82786




Ki 67


—
Mllt3

Mus musculus transcribed sequences
24
3.0
AV381294


Mllt3
Mllt3
myeloid/lymphoid or mixed lineage-
114
2.2
AK019458




leukemia translocation to 3 homolog




(Drosophila)


Mlp
Mlp
MARCKS-like protein
92
2.2
BB491008


Mlp
Mlp
MARCKS-like protein
538
3.2
AV110584


Mmp14
Mmp14
matrix metalloproteinase 14 (membrane-
97
5.1
NM_008608




inserted)


Mmp14
Mmp14
matrix metalloproteinase 14 (membrane-
216
5.1
NM_008608




inserted)


Mmp19
Mmp19
matrix metalloproteinase 19
7
4.4
AF153199


Mmp7
Mmp7
matrix metalloproteinase 7
50
6.4
NM_010810


D930043C02Rik
Mnab
RIKEN cDNA D930043C02 gene
23
2.3
BM210927


D930043C02Rik
Mnab
RIKEN cDNA D930043C02 gene
28
2.3
AA709668


Mns1
Mns1
meiosis-specific nuclear structural protein 1
27
3.7
NM_008613


4022402H07Rik
Mobk1b
RIKEN cDNA 4022402H07 gene
1399
2.2
BC011285


—
Mpa2l

Mus musculus transcribed sequence with
191
118.4
BM241485




weak similarity to protein sp: P32456




(H. sapiens) GBP2_HUMAN Interferon-




induced guanylate-binding protein 2




(Guanine nucleotide-binding protein 2)


—
Mpa2l

Mus musculus transcribed sequences
339
72.1
BG092512


Mpeg1
Mpeg1
macrophage expressed gene 1
402
22.7
L20315


Mre11a
Mre11a
meiotic recombination 11 homolog A (S. cerevisiae)
190
2.3
NM_018736


Ms4a1
Ms4a1
membrane-spanning 4-domains,
28
4.0
BB236617




subfamily A, member 1


Ms4a1
Ms4a1
membrane-spanning 4-domains,
17
3.7
BB236617




subfamily A, member 1


Ms4a4b
Ms4a4b
membrane-spanning 4-domains,
88
56.0
BB199001




subfamily A, member 4B


Ms4a4d
Ms4a4d
membrane-spanning 4-domains,
96
12.6
NM_025658




subfamily A, member 4D


—
Ms4a6b

Mus musculus adult male aorta and vein
92
3.1
BB221406




cDNA, RIKEN full-length enriched library,




clone: A530066O14 product: unknown




EST, full insert sequence


—
Ms4a6b

Mus musculus adult male aorta and vein
37
4.2
BB218965




cDNA, RIKEN full-length enriched library,




clone: A530066O14 product: unknown




EST, full insert sequence


Ms4a6b
Ms4a6b
membrane-spanning 4-domains,
126
45.7
NM_027209




subfamily A, member 6B


Ms4a6c
Ms4a6c
membrane-spanning 4-domains,
132
14.8
AF237910




subfamily A, member 6C


Ms4a11
Ms4a6d
membrane-spanning 4-domains,
50
38.3
NM_026835




subfamily A, member 11


Ms4a11
Ms4a6d
membrane-spanning 4-domains,
57
39.2
NM_026835




subfamily A, member 11


A430103C15Rik
Ms4a7
RIKEN cDNA A430103C15 gene
105
5.4
BC024402


Msn
Msn
moesin
1945
2.3
NM_010833


Msn
Msn
moesin
4591
2.1
NM_010833


Msr1
Msr1
macrophage scavenger receptor 1
25
12.3
L04274


Msr1
Msr1
macrophage scavenger receptor 1
44
9.9
AA183642


Msr1
Msr1
macrophage scavenger receptor 1
58
9.8
BC003814


Mt2
Mt2
metallothionein 2
3122
2.9
AA796766


Mthfd2
Mthfd2
methylenetetrahydrofolate
134
3.6
BG076333




dehydrogenase (NAD+ dependent),




methenyltetrahydrofolate cyclohydrolase


Mthfd2
Mthfd2
methylenetetrahydrofolate
111
6.4
BG076333




dehydrogenase (NAD+ dependent),




methenyltetrahydrofolate cyclohydrolase


Mvp
Mvp
major vault protein
281
3.9
NM_080638


—
Mvp
—
396
4.1
BB139464


Mx1
Mx1
myxovirus (influenza virus) resistance 1
54
6.9
M21039


Myadm
Myadm
myeloid-associated differentiation marker
716
2.1
BI078799


Myb
Myb
myeloblastosis oncogene
10
26.7
NM_033597


Myb
Myb
myeloblastosis oncogene
29
7.7
NM_033597


Myb
Myb
myeloblastosis oncogene
5
7.0
BC011513


Myc
Myc
myelocytomatosis oncogene
198
3.5
BC006728


Myd88
Myd88
myeloid differentiation primary response
590
3.9
BC005591




gene 88


—
Myh9
—
211
2.5
C80049


Myo1f
Myo1f
myosin IF
57
10.4
AK021181


Myo1f
Myo1f
myosin IF
16
30.8
AK021181


Myo1g
Myo1g
myosin IG
76
15.2
BB235320


Myo9b
Myo9b
myosin IXb
239
2.5
NM_015742


Nasp
Nasp
nuclear autoantigenic sperm protein
470
2.3
BB493242




(histone-binding)


Ncf1
Ncf1
neutrophil cytosolic factor 1
155
8.1
AI844633


Ncf2
Ncf2
neutrophil cytosolic factor 2
121
5.7
NM_010877


Ncor1
Ncor1
nuclear receptor co-repressor 1
24
2.5
AI481996


—
Nefh

Mus musculus mRNA for mKIAA0845
18
10.0
M35131




protein


BC034753
Neil3
cDNA sequence BC034753
29
2.1
AV316939


Nek2
Nek2
NIMA (never in mitosis gene a)-related
112
4.2
C77054




expressed kinase 2


Nek6
Nek6
NIMA (never in mitosis gene a)-related
237
2.3
BC019524




expressed kinase 6


—
Net1

Mus musculus transcribed sequences
40
4.1
AV247312


Nfatc1
Nfatc1
nuclear factor of activated T-cells,
71
4.5
AF239169




cytoplasmic 1


Nfatc1
Nfatc1
nuclear factor of activated T-cells,
187
3.6
NM_016791




cytoplasmic 1


Nfatc1
Nfatc1
nuclear factor of activated T-cells,
204
2.6
BB356861




cytoplasmic 1


Nfatc2
Nfatc2
nuclear factor of activated T-cells,
112
3.7
BM122872




cytoplasmic 2


Nfkb1
Nfkb1
nuclear factor of kappa light chain gene
654
2.6
L28118




enhancer in B-cells 1, p105


Nfkb2
Nfkb2
nuclear factor of kappa light polypeptide
141
3.9
AF155372




gene enhancer in B-cells 2, p49/p100


Nfkbia
Nfkbia
nuclear factor of kappa light chain gene
4502
3.1
AI462015




enhancer in B-cells inhibitor, alpha


Nfkbia
Nfkbia
nuclear factor of kappa light chain gene
666
3.2
AI462015




enhancer in B-cells inhibitor, alpha


Nfkbie
Nfkbie
nuclear factor of kappa light polypeptide
122
4.5
AK011965




gene enhancer in B-cells inhibitor,




epsilon


—
Nfkbie
—
194
9.7
BB820441


AA408868
Nfkbiz
expreexpressed sequence AA408868
82
10.1
BM240058


AA408868
Nfkbiz
expreexpressed sequence AA408868
117
5.3
AB026551


AA408868
Nfkbiz
expreexpressed sequence AA408868
169
10.8
AB026551


Ngfr
Ngfr
nerve growth factor receptor (TNFR
32
8.3
BB151515




superfamily, member 16)


Niban
Niban
niban protein
87
3.4
NM_022018


Nical
Nical
NEDD9 interacting protein with calponin
22
6.0
BB209438




homology and LIM domains


Nin
Nin
ninein
190
2.3
AK014241


Nkg7
Nkg7
natural killer cell group 7 sequence
55
36.5
NM_024253


Nktr
Nktr
natural killer tumor recognition sequence
133
2.2
AW987751


Nmi
Nmi
N-myc (and STAT) interactor
687
6.7
BC002019


Nnmt
Nnmt
nicotinamide N-methyltransferase
53
6.6
AK006371


Nol5a
Nol5a
nucleolar protein 5A
326
2.4
BF660256


Nol5a
Nol5a
nucleolar protein 5A
436
2.2
BM249243


Npc2
Npc2
Niemann Pick type C2
100
3.9
BG071996


—
Nr4a3

Mus musculus transcribed sequences
20
7.2
BE692107


Nr6a1
Nr6a1
nuclear receptor subfamily 6, group A,
46
2.0
U09563




member 1


Nras
Nras; N-ras
neuroblastoma ras oncogene
462
2.4
AK010412


Nrf1
Nrf1
nuclear respiratory factor 1
97
2.1
BM221378


2310014H01Rik
Nrm
RIKEN cDNA 2310014H01 gene
58
3.1
NM_134122


Nrn1
Nrn1
neuritin 1
81
2.8
AK003046


—
Nrp1

Mus musculus transcribed sequences
193
2.0
AV291009


—
Nt5c2

Mus musculus transcribed sequences
41
2.8
AU017183


AW541137
Nup107
expressed sequence AW541137
242
2.1
BC004655


Nup153
Nup153
nucleoporin 153
150
2.3
C88147


Nup210
Nup210
nucleoporin 210
356
3.1
NM_018815


Nupr1
Nupr1
nuclear protein 1
743
2.1
NM_019738


Oact1
Oact1
O-acyltransferase (membrane bound)
84
3.8
AV366860




domain containing 1


Oas1g
Oas1a
2′-5′ oligoadenylate synthetase 1G
345
6.9
BC018470


Oasl1
Oasl1
2′-5′ oligoadenylate synthetase-like 1
174
4.0
AB067533


Oasl2
Oasl2
2′-5′ oligoadenylate synthetase-like 2
209
17.4
BQ033138


Olfr56
Olfr56
olfactory receptor 56
336
39.5
NM_008330


Olr1
Olr1
oxidized low density lipoprotein (lectin-
8
7.9
NM_138648




like) receptor 1


A130090K04Rik
Oprm1
RIKEN cDNA A130090K04 gene
347
3.1
BQ176089


Osmr
Osmr
oncostatin M receptor
96
5.0
AB015978


Osmr
Osmr
oncostatin M receptor
286
4.7
AB015978


—
P2rx7

Mus musculus transcribed sequences
46
2.7
AI552982


P2ry10
P2ry10
purinergic receptor P2Y, G-protein
19
18.0
AK020001




coupled 10


P2ry12
P2ry12
purinergic receptor P2Y, G-protein
32
3.2
AK013804




coupled 12


Gpr86
P2ry13
G protein-coupled receptor 86
68
4.5
AK008013


Gpr105
P2ry14
G protein-coupled receptor 105
220
2.2
AF177211


P2ry6
P2ry6
pyrimidinergic receptor P2Y, G-protein
110
5.1
BC027331




coupled, 6


—
Pabpc1

Mus musculus 0 day neonate thymus
63
2.0
AW552076




cDNA, RIKEN full-length enriched library,




clone: A430039M01 product: unknown




EST, full insert sequence


Padi2
Padi2
peptidyl arginine deiminase, type II
110
2.1
NM_008812


Panx1
Panx1
pannexin 1
88
3.2
NM_019482


5330431N24Rik
Parp11
RIKEN cDNA 5330431N24 gene
264
3.1
BB026163


BC021340
Parp14
cDNA sequence BC021340
256
16.1
BC021340


Adprtl3
Parp3
ADP-ribosyltransferase (NAD+; poly
527
2.1
AW990611




(ADP-ribose polymerase)-like 3


Adprtl3
Parp3
ADP-ribosyltransferase (NAD+; poly
1373
2.6
BC014870




(ADP-ribose polymerase)-like 3


—
Parp8

Mus musculus 13 days embryo forelimb
123
2.3
C85455




cDNA, RIKEN full-length enriched library,




clone: 5930433N17 product: unknown




EST, full insert sequence


BC003281
Parp9
cDNA sequence BC003281
460
12.0
NM_030253


1110035O14Rik
Pbef1
RIKEN cDNA 1110035O14 gene
2754
2.4
AW989410


D14Ertd732e
Pbk
DNA segment, Chr 14, ERATO Doi 732,
200
3.2
NM_023209




expressed


Pcna
Pcna
proliferating cell nuclear antigen
3700
2.3
BC010343


Arpc1b
Pdap1
actin related protein 2/3 complex, subunit
690
6.1
BE979985




1B


Pdcd1lg1
Pdcd1lg1
programmed cell death 1 ligand 1
73
45.1
NM_021893


Pdcd1lg2
Pdcd1lg2
programmed cell death 1 ligand 2
57
5.6
NM_021396


Pde4b
Pde4b
phosphodiesterase 4B, cAMP specific
76
2.9
BG793493


Pdk4
Pdk4
pyruvate dehydrogenase kinase,
283
3.1
NM_013743




isoenzyme 4


Pdlim1
Pdlim1
PDZ and LIM domain 1 (elfin)
272
2.6
NM_016861


Ril
Pdlim4
reversion induced LIM gene
63
3.6
NM_019417


Peli1
Peli1
pellino 1
476
2.8
BC016515


Per1
Per1
period homolog 1 (Drosophila)
62
3.9
AF022992


Pfc
Pfc
properdin factor, complement
24
16.5
BB800282


Pfkfb3
Pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-
164
3.4
NM_133232




biphosphatase 3


Pfkp
Pfkp
phosphofructokinase, platelet
1402
2.7
NM_019703


Phemx
Phemx
pan hematopoietic expression
41
3.8
AF175771


4933417L10Rik
Phf11
RIKEN cDNA 4933417L10 gene
301
4.8
AV280841


E130113K22Rik
Phf20l1
RIKEN cDNA E130113K22 gene
114
2.1
AV349060


B2m
Phf20l1
beta-2 microglobulin
13469
2.0
BF715219


4931428F02Rik
Phf6
RIKEN cDNA 4931428F02 gene
187
2.5
AA275278


4931428F02Rik
Phf6
RIKEN cDNA 4931428F02 gene
151
2.4
BG073473


Pigr
Pigr
polymeric immunoglobulin receptor
3030
4.4
AV027632


Pigr
Pigr
polymeric immunoglobulin receptor
2667
3.0
NM_011082


Pik3ap1
Pik3ap1
phosphoinositide-3-kinase adaptor
64
7.8
BI684288




protein 1


Pik3cd
Pik3cd
phosphatidylinositol 3-kinase catalytic
111
4.7
BB700084




delta polypeptide


Pik3cg
Pik3cg
phosphoinositide-3-kinase, catalytic,
146
2.6
BB205102




gamma polypeptide


Pik3r1
Pik3r1
phosphatidylinositol 3-kinase, regulatory
564
2.8
M60651




subunit, polypeptide 1 (p85 alpha)


—
Pik3r5

Mus musculus transcribed sequences
41
5.0
AV230647


Pilra
Pilra
paired immunoglobin-like type 2 receptor
108
4.3
BB775785




alpha


Pim1
Pim1
proviral integration site 1
546
4.2
BE631223


Pip5k2a
Pip5k2a
phosphatidylinositol-4-phosphate 5-
104
2.6
AK012196




kinase, type II, alpha


Pip5k2a
Pip5k2a
phosphatidylinositol-4-phosphate 5-
420
3.0
AK012196




kinase, type II, alpha


Pira10
Pira6
paired-Ig-like receptor A10
69
15.0
NM_011093


—
Pira6
—
10
15.5
NM_011087


Pirb
Pirb
paired-Ig-like receptor B
13
47.9
U96693


Pitpnm
Pitpnm1
phosphatidylinositol membrane-
461
2.1
BB206460




associated


Pkib
Pkib
protein kinase inhibitor beta, cAMP
44
3.8
AV047342




dependent, testis specific


Pla2g4a
Pla2g4a
phospholipase A2, group IVA (cytosolic,
270
4.4
NM_008869




calcium-dependent)


Pla2g7
Pla2g7
phospholipase A2, group VII (platelet-
338
5.8
AK005158




activating factor acetylhydrolase, plasma)


Plac8
Plac8
placenta-specific 8
756
14.2
AF263458


—
Plagl2

Mus musculus transcribed sequence with
33
2.6
BF584971




weak similarity to protein




ref: NP_081764.1 (M. musculus) RIKEN




cDNA 5730493B19 [Mus musculus]


Plagl2
Plagl2
pleiomorphic adenoma gene-like 2
49
3.4
NM_018807


Plcg2
Plcg2
phospholipase C, gamma 2
521
2.1
AW546508


Plcl2
Plcl2
phospholipase C-like 2
144
5.4
BM207017


Plekha2
Plekha2
pleckstrin homology domain-containing,
346
2.3
NM_031257




family A (phosphoinositide binding




specific) member 2


Plekha2
Plekha2
pleckstrin homology domain-containing,
139
2.0
BE852755




family A (phosphoinositide binding




specific) member 2


Plekha2
Plekha2
pleckstrin homology domain-containing,
611
3.1
NM_031257




family A (phosphoinositide binding




specific) member 2


2410005C22Rik
Plekha4
RIKEN cDNA 2410005C22 gene
46
3.2
BC024961


Cnk
Plk3
cytokine inducible kinase
117
2.2
BM947855


Stk18
Plk4
serine/threonine kinase 18
128
2.7
BB706079


Stk18
Plk4
serine/threonine kinase 18
116
4.9
AI385771


Plp2
Plp2
proteolipid protein 2
1503
2.0
AK012816


Plxnc1
Plxnc1
plexin C1
30
3.2
BB476707


Plxnc1
Plxnc1
plexin C1
126
2.9
BB476707


Plxnc1
Plxnc1
plexin C1
48
5.5
BB476707


Pnp
Pnp
purine-nucleoside phosphorylase
4116
2.2
AK008143


Pola1
Pola1
polymerase (DNA directed), alpha 1
155
2.6
NM_008892


Pold1
Pold1
polymerase (DNA directed), delta 1,
164
2.1
BC009128




catalytic subunit


Pold3
Pold3
polymerase (DNA-directed), delta 3,
223
1.9
AK010805




accessory subunit


Pole2
Pole2
polymerase (DNA directed), epsilon 2
181
3.2
AF036898




(p59 subunit)


Polh
Polh
polymerase (DNA directed), eta (RAD 30
150
3.5
BB066090




related)


Pou2af1
Pou2af1
POU domain, class 2, associating factor 1
15
9.4
NM_011136


Ppfia4
Ppfia4;
protein tyrosine phosphatase, receptor
24
4.5
AK003571



1110008G13Rik
type, f polypeptide (PTPRF), interacting




protein (liprin), alpha 4


2410005L11Rik
Ppil5
RIKEN cDNA 2410005L11 gene
9
3.0
BG067404


Ppp1r12a
Ppp1r12a
protein phosphatase 1, regulatory
1000
2.3
AV309184




(inhibitor) subunit 12A


—
Ppp1r12a

Mus musculus 7 days embryo whole
86
2.7
BB410003




body cDNA, RIKEN full-length enriched




library, clone: C430016H01




product: unknown EST, full insert




sequence


Ppp1r12a
Ppp1r12a
protein phosphatase 1, regulatory
550
2.0
BI653999




(inhibitor) subunit 12A


Ppp1r12a
Ppp1r12a
protein phosphatase 1, regulatory
641
2.2
AV309184




(inhibitor) subunit 12A


—
Ppt1

Mus musculus 12 days embryo spinal
60
3.0
BB461203




ganglion cDNA, RIKEN full-length




enriched library, clone: D130070K05




product: unknown EST, full insert




sequence


Prdm1
Prdm1
PR domain containing 1, with ZNF
157
2.1
NM_007548




domain


Prg
Prg1
proteoglycan, secretory granule
2020
4.9
NM_011157


Prim2
Prim2
DNA primase, p58 subunit
137
2.2
NM_008922


Prkcb
Prkcb1
protein kinase C, beta
27
5.8
BF660388


Prkch
Prkch
protein kinase C, eta
412
2.7
BM243756


Prkch
Prkch
protein kinase C, eta
259
3.4
NM_008856


Prkcq
Prkcq
protein kinase C, theta
159
3.0
AB062122


AI325941
Prkd2
expressed sequence AI325941
151
2.2
BB204677


AI325941
Prkd2
expressed sequence AI325941
103
2.7
AW557946


Prkr
Prkr
protein kinase, interferon-inducible
165
5.0
BE911144




double stranded RNA dependent


Procr
Procr
protein C receptor, endothelial
163
4.7
NM_011171


Pros1
Pros1
protein S (alpha)
445
2.0
Z25469


Prrx1
Prrx1
paired related homeobox 1
24
2.0
BB051738


Pscd4
Pscd4
pleckstrin homology, Sec7 and coiled/coil
22
18.8
AK010908




domains 4


Pscdbp
Pscdbp
pleckstrin homology, Sec7 and coiled-coil
682
3.6
BC007144




domains, binding protein


BC046518
Psd4
cDNA sequence BC046518
122
2.2
BM221809


Psma6
Psma6
proteasome (prosome, macropain)
12
2.8
AA189256




subunit, alpha type 6


Psmb10
Psmb10
proteasome (prosome, macropain)
525
14.7
NM_013640




subunit, beta type 10


—
Psmb2

Mus musculus 10 days neonate
38
2.4
BM201103




cerebellum cDNA, RIKEN full-length




enriched library, clone: B930059K21




product: unknown EST, full insert




sequence


Psmb8
Psmb8
proteosome (prosome, macropain)
461
27.5
NM_010724




subunit, beta type 8 (large multifunctional




protease 7)


Psmb8
Psmb8
proteosome (prosome, macropain)
17
24.0
AV068122




subunit, beta type 8 (large multifunctional




protease 7)


Tap1
Psmb9
transporter 1, ATP-binding cassette, sub-
127
29.5
AW048052




family B (MDR/TAP)


Psmb9
Psmb9
proteosome (prosome, macropain)
298
30.2
NM_013585




subunit, beta type 9 (large multifunctional




protease 2)


Psme1
Psme1
proteasome (prosome, macropain) 28
2901
3.1
NM_011189




subunit, alpha


Psme2
Psme2
proteasome (prosome, macropain) 28
1669
5.3
NM_011190




subunit, beta


Ptger2
Ptger2
prostaglandin E receptor 2 (subtype EP2)
19
13.1
BC005440


Ptger4
Ptger4
prostaglandin E receptor 4 (subtype EP4)
51
2.8
NM_008965


Ptger4
Ptger4
prostaglandin E receptor 4 (subtype EP4)
259
5.0
BC011193


Ptgs2
Ptgs2
prostaglandin-endoperoxide synthase 2
32
4.4
M94967


Ptgs2
Ptgs2
prostaglandin-endoperoxide synthase 2
31
9.3
M94967


Ptk9l
Ptk9l
protein tyrosine kinase 9-like (A6-related
125
3.4
AK002699




protein)


Ptk9l
Ptk9l
protein tyrosine kinase 9-like (A6-related
328
3.8
BB397672




protein)


Ptpn12
Ptpn12
protein tyrosine phosphatase, non-
1107
2.2
X63440




receptor type 12


Ptpn18
Ptpn18
protein tyrosine phosphatase, non-
338
2.9
NM_011206




receptor type 18


Ptprc
Ptprc
protein tyrosine phosphatase, receptor
516
18.2
NM_011210




type, C


—
Ptprc

Mus musculus 16 days neonate thymus
28
10.1
BM239436




cDNA, RIKEN full-length enriched library,




clone: A130082N01




product: unclassifiable, full insert




sequence


Ptprcap
Ptprcap
protein tyrosine phosphatase, receptor
140
7.5
NM_016933




type, C polypeptide-associated protein


Ptpre
Ptpre
protein tyrosine phosphatase, receptor
102
4.5
U35368




type, E


Ptpre
Ptpre
protein tyrosine phosphatase, receptor
73
3.6
U35368




type, E


Pttg1
Pttg1
pituitary tumor-transforming 1
408
2.3
AF069051


9130417A21Rik
Pycard
RIKEN cDNA 9130417A21 gene
396
6.5
BG084230


Pycs
Pycs
pyrroline-5-carboxylate synthetase
136
2.9
BF148128




(glutamate gamma-semialdehyde




synthetase)


Pycs
Pycs
pyrroline-5-carboxylate synthetase
99
6.6
BB251523




(glutamate gamma-semialdehyde




synthetase)


2010317E03Rik
Pyp
RIKEN cDNA 2010317E03 gene
1519
2.9
NM_026438


Qpct
Qpct
glutaminyl-peptide cyclotransferase
27
3.8
BB150720




(glutaminyl cyclase)


Rab19
Rab19
RAB19, member RAS oncogene family
108
2.8
BM241400


Rab32
Rab32
RAB32, member RAS oncogene family
564
2.6
NM_026405


Rab37
Rab37
RAB37, member of RAS oncogene family
43
2.1
BB433704


D330025I23Rik
Rab8b
RIKEN cDNA D330025I23 gene
840
4.1
BM214169


Rac2
Rac2
RAS-related C3 botulinum substrate 2
169
10.9
NM_009008


Rad18
Rad18
RAD18 homolog (S. cerevisiae)
73
2.3
BC011120


Rad18
Rad18
RAD18 homolog (S. cerevisiae)
18
4.2
BB530954


Rad23b
Rad23b
RAD23b homolog (S. cerevisiae)
21
2.4
BB482313


Rad54l
Rad54l
RAD54 like (S. cerevisiae)
17
8.1
AV310220


Ramp1
Ramp1
receptor (calcitonin) activity modifying
66
2.3
NM_016894




protein 1


Ranbp2
Ranbp2
RAN binding protein 2
61
2.6
BB208180


Rap2b
Rap2b
RAP2B, member of RAS oncogene
60
3.4
BB390705




family


Rap2b
Rap2b
RAP2B, member of RAS oncogene
196
2.7
BB645629




family


Rap2c
Rap2c
RAP2C, member of RAS oncogene
464
2.0
AK008416




family


Rap2c
Rap2c
RAP2C, member of RAS oncogene
415
2.2
AK008416




family


Rasa3
Rasa3
RAS p21 protein activator 3
142
4.6
NM_009025


Rasd1
Rasd1
RAS, dexamethasone-induced 1
136
4.7
BB217136


Rasgrp1
Rasgrp1
RAS guanyl releasing protein 1
181
3.2
BE691356


Rassf4
Rassf4
Ras association (RaIGDS/AF-6) domain
28
10.0
AV291679




family 4


Rbl1
Rbl1
retinoblastoma-like 1 (p107)
314
5.8
U27177


Rbl1
Rbl1
retinoblastoma-like 1 (p107)
59
3.2
U27178


Rbm3
Rbm3
RNA binding motif protein 3
193
2.5
AK011224


Rbmxrt
Rbmxrt
RNA binding motif protein, X
887
2.1
NM_009033




chromosome retrogene


Rcn
Rcn1
reticulocalbin
286
4.2
NM_009037


Refbp2
Refbp2
RNA and export factor binding protein 2
611
2.1
NM_019484


Rel
Rel
reticuloendotheliosis oncogene
24
3.8
NM_009044


Relb
Relb
avian reticuloendotheliosis viral (v-rel)
109
3.0
NM_009046




oncogene related B


Rfc3
Rfc3
replication factor C (activator 1) 3
132
2.3
BC026795


Rfc3
Rfc3
replication factor C (activator 1) 3
128
2.9
AK013095


Eif4a2
Rfc4
eukaryotic translation initiation factor 4A2
105
2.9
BB251459


Rfc4
Rfc4
replication factor C (activator 1) 4
188
3.0
BC003335


—
Rfwd2

Mus musculus 9.5 days embryo
40
2.0
BB294853




parthenogenote cDNA, RIKEN full-length




enriched library, clone: B130031H03




product: unclassifiable, full insert




sequence


Rgs19
Rgs19
regulator of G-protein signaling 19
73
6.2
BB233670


Rgs2
Rgs2
regulator of G-protein signaling 2
425
2.0
AF215668


Rgs2
Rgs2
regulator of G-protein signaling 2
303
2.6
BB034265


Rgs2
Rgs2
regulator of G-protein signaling 2
454
2.6
AF215668


Arhb
Rhob
ras homolog gene family, member B
2877
2.9
BC018275


Arhg
Rhog
ras homolog gene family, member G
467
2.0
NM_019566


Arhh
Rhoh
ras homolog gene family, member H
67
5.0
BM243660


—
Rims2

Mus musculus transcribed sequences
285
2.1
C79043


Ripk2
Ripk2
receptor (TNFRSF)-interacting serine-
225
2.0
NM_138952




threonine kinase 2


Ris2
Ris2
retroviral integration site 2
631
2.6
AF477481


Ris2
Ris2
retroviral integration site 2
228
2.0
AF477481


9530043P15Rik
Rnase6
RIKEN cDNA 9530043P15 gene
66
6.5
AW825994


Rnaset2
Rnaset2;
ribonuclease T2
154
2.2
AK015947



RNASE6PL;



0610007O07Rik;



4833423A10Rik;



4930532K22Rik


Trpc2
Rnf121
transient receptor potential cation
35
2.5
AW324327




channel, subfamily C, member 2


Rnpc2
Rnpc2
RNA-binding region (RNP1, RRM)
162
2.2
BB203348




containing 2


Rnpc2
Rnpc2
RNA-binding region (RNP1, RRM)
305
2.5
C79248




containing 2


Rnpc2
Rnpc2
RNA-binding region (RNP1, RRM)
233
2.3
C79248




containing 2


—
Rnu22

Mus musculus 9 days embryo whole
352
2.3
BQ177137




body cDNA, RIKEN full-length enriched




library, clone: D030060F23 product: Mus




musculus U22 snoRNA host gene (UHG)




gene, complete sequence, full insert




sequence


—
Rnu22

Mus musculus 9 days embryo whole
155
7.0
BB493265




body cDNA, RIKEN full-length enriched




library, clone: D030060F23 product: Mus




musculus U22 snoRNA host gene (UHG)




gene, complete sequence, full insert




sequence


Rp2h
Rp2h
retinitis pigmentosa 2 homolog (human)
185
2.3
BB431808


Rp2h
Rp2h
retinitis pigmentosa 2 homolog (human)
672
2.4
BB431808


Rpa2
Rpa2
replication protein A2
238
2.5
BC004578


Rpa2
Rpa2; Rf-A2
replication protein A2
208
2.2
AK011530


Rpgrip1
Rpgrip1
retinitis pigmentosa GTPase regulator
45
35.9
NM_023879




interacting protein 1


Rpl12
Rpl12
ribosomal protein L12
82
3.2
BG807990


Rps25
Rps25
ribosomal protein S25
250
2.1
BM729504


3010033P07Rik
Rps9
RIKEN cDNA 3010033P07 gene
188
16.9
AA762498


Rrad
Rrad
Ras-related associated with diabetes
33
6.6
NM_019662


Rrm1
Rrm1
ribonucleotide reductase M1
383
3.3
BB758819


Rrm1
Rrm1
ribonucleotide reductase M1
380
3.3
BB758819


2510004L01Rik
Rsad2
RIKEN cDNA 2510004L01 gene
1215
2.5
BB132493


—
Rtn4

Mus musculus 16 days embryo head
158
3.4
BB648600




cDNA, RIKEN full-length enriched library,




clone: C130026I10 product: unknown




EST, full insert sequence


—
Rtn4

Mus musculus 16 days embryo head
109
2.9
BG072267




cDNA, RIKEN full-length enriched library,




clone: C130026I10 product: unknown




EST, full insert sequence


Runx3
Runx3
runt related transcription factor 3
19
9.3
AV233043


S100a10
S100a10
S100 calcium binding protein A10
103
1.9
BB450829




(calpactin)


S100a4
S100a4
S100 calcium binding protein A4
120
13.7
D00208


S100a6
S100a6
S100 calcium binding protein A6
1217
2.8
NM_011313




(calcyclin)


S100a8
S100a8
S100 calcium binding protein A8
24
9.4
NM_013650




(calgranulin A)


S100a9
S100a9
S100 calcium binding protein A9
29
8.9
NM_009114




(calgranulin B)


Saa1
Saa1
serum amyloid A 1
18
20.0
NM_009117


Saa2
Saa2
serum amyloid A 2
33
3.0
NM_011314


Saa2
Saa2
serum amyloid A 2
62
7.0
NM_011314


Saa3
Saa3
serum amyloid A 3
110
8.6
NM_011315


Samhd1
Samhd1
SAM domain and HD domain, 1
418
11.3
NM_018851


Samhd1
Samhd1
SAM domain and HD domain, 1
185
11.4
BF148012


Samhd1
Samhd1
SAM domain and HD domain, 1
8
16.3
AV376100


Samsn1
Samsn1
SAM domain, SH3 domain and nuclear
49
9.1
NM_023380




localisation signals, 1


B130024B19Rik
Sart2
RIKEN cDNA B130024B19 gene
62
5.7
BM207218


Satb1
Satb1
special AT-rich sequence binding protein 1
52
5.0
AV172776


Satb1
Satb1
special AT-rich sequence binding protein 1
68
2.9
AV172776


Scarb2
Scarb2
scavenger receptor class B, member 2
783
2.0
NM_007644


Sdc1
Sdc1
syndecan 1
337
2.9
BB533095


Sdccag8
Sdccag8
serologically defined colon cancer
114
3.5
BG695418




antigen 8


—
Sec8l1

Mus musculus transcribed sequence with
59
2.3
BM941583




strong similarity to protein sp: P00722 (E. coli)




BGAL_ECOLI Beta-galactosidase




(Lactase)


Sectm1
Sectm1
secreted and transmembrane 1
516
2.9
AI481997


Sectm1
Sectm1
secreted and transmembrane 1
3261
3.0
AI481997


Sell
Sell
selectin, lymphocyte
69
14.0
M36005


Sell
Sell
selectin, lymphocyte
86
9.7
M36005


E330036L07Rik
Senp1
RIKEN cDNA E330036L07 gene
75
2.2
BC023129


Sepw1
Sepw1
selenoprotein W, muscle 1
1468
2.0
BB464434


Serpina10
Serpina10
serine (or cysteine) proteinase inhibitor,
211
44.0
BC018416




clade A (alpha-1 antiproteinase,




antitrypsin), member 10


Serpina1a
Serpina1a
serine (or cysteine) proteinase inhibitor,
156
6.4
NM_009243




clade A, member 1a


Serpina1b
Serpina1b
serine (or cysteine) proteinase inhibitor,
2182
2.0
NM_009244




clade A, member 1b


Serpina3g
Serpina3g
serine (or cysteine) proteinase inhibitor,
92
107.8
BC002065




clade A, member 3G


Serpina3n
Serpina3n
serine (or cysteine) proteinase inhibitor,
18
10.9
NM_009252




clade A, member 3N


Serpinb1a
Serpinb1a
serine (or cysteine) proteinase inhibitor,
78
2.7
AF426024




clade B, member 1a


Serpinb1a
Serpinb1a
serine (or cysteine) proteinase inhibitor,
256
3.2
AF426024




clade B, member 1a


Serpinb6a
Serpinb6a
serine (or cysteine) proteinase inhibitor,
679
2.3
NM_009254




clade B, member 6a


Serpinb6b
Serpinb6b
serine (or cysteine) proteinase inhibitor,
375
4.2
NM_011454




clade B, member 6b


Serpinb9
Serpinb9
serine (or cysteine) proteinase inhibitor,
972
6.3
NM_009256




clade B, member 9


Serpinb9
Serpinb9
serine (or cysteine) proteinase inhibitor,
323
5.3
BE686716




clade B, member 9


Serpine1
Serpine1
serine (or cysteine) proteinase inhibitor,
80
4.3
NM_008871




clade E, member 1


Serping1
Serping1
serine (or cysteine) proteinase inhibitor,
2372
5.4
NM_009776




clade G, member 1


—
Sertad4

Mus musculus 16 days embryo head
96
5.2
BQ174721




cDNA, RIKEN full-length enriched library,




clone: C130018M11




product: unclassifiable, full insert




sequence


Sfpi1
Sfpi1
SFFV proviral integration 1
116
5.5
NM_011355


Sfrs3
Sfrs3
splicing factor, arginine/serine-rich 3
1401
2.2
BB492363




(SRp20)


Sfrs7
Sfrs7
splicing factor, arginine/serine-rich 7
1701
2.1
BC027391


3300001M08Rik
Sgol1
RIKEN cDNA 3300001M08 gene
16
3.9
BB410537


Sh3bgrl
Sh3bgrl
SH3-binding domain glutamic acid-rich
1195
2.0
AK004519




protein like


Sh3bgr1
Sh3bgrl
SH3-binding domain glutamic acid-rich
14
4.7
BB548587




protein like


Sh3bgrl3
Sh3bgrl3
SH3 domain binding glutamic acid-rich
1255
4.7
NM_080559




protein-like 3


Sh3bp2
Sh3bp2
SH3-domain binding protein 2
296
2.3
BC010198


Sh3kbp1
Sh3kbp1
SH3-domain kinase binding protein 1
18
3.8
BB766215


Sh3kbp1
Sh3kbp1
SH3-domain kinase binding protein 1
161
6.3
BB326929


Shcbp1
Shcbp1
Shc SH2-domain binding protein 1
35
12.4
NM_011369


—
Siat4c
—
32
3.4
BE954474


Siat8d
Siat8d
sialyltransferase 8 (alpha-2, 8-
166
4.6
NM_009183




sialyltransferase) D


Sil
Sil
Tal1 interrupting locus
30
3.0
BC004585


Sit
Sit
SHP2 interacting transmembrane adaptor
57
2.2
NM_019436


Slamf1
Slamf1
signaling lymphocytic activation molecule
72
3.0
BB132695




family member 1


Slamf1
Slamf1
signaling lymphocytic activation molecule
12
7.9
BB132695




family member 1


Slamf7
Slamf7
SLAM family member 7
58
5.4
AK016183


Slamf8
Slamf8
SLAM family member 8
27
65.9
BC024587


Slamf9
Slamf9
SLAM family member 9
135
5.9
NM_029612


Slbp
Slbp
stem-loop binding protein
1160
2.3
NM_009193


Slc11a1
Slc11a1
solute carrier family 11 (proton-coupled
177
6.5
NM_013612




divalent metal ion transporters), member 1


Slc15a3
Slc15a3
solute carrier family 15, member 3
38
24.8
NM_023044


Slc20a1
Slc20a1
solute carrier family 20, member 1
890
2.6
NM_015747


2610016M12Rik
Slc25a24
RIKEN cDNA 2610016M12 gene
93
3.1
BF578055


2610016M12Rik
Slc25a24
RIKEN cDNA 2610016M12 gene
261
4.6
BM230959


Slc28a2
Slc28a2
solute carrier family 28 (sodium-coupled
9
21.0
NM_021520




nucleoside transporter), member 2


Slc2a3
Slc2a3
solute carrier family 2 (facilitated glucose
68
4.2
BB414515




transporter), member 3


Slc2a6
Slc2a6
solute carrier family 2 (facilitated glucose
14
15.4
BB196807




transporter), member 6


Slc31a2
Slc31a2
solute carrier family 31, member 2
350
2.5
NM_025286


Tramd1
Slc36a2
tramdorin 1 (transmembrane domain rich
26
3.3
AI596194




protein)


Slc38a1
Slc38a1
solute carrier family 38, member 1
193
2.4
NM_134086


Slc38a1
Slc38a1
solute carrier family 38, member 1
35
18.6
BF165681


F730005G13
Slc39a2
hypothetical protein F730005G13
23
5.0
BB049001


Slc39a6
Slc39a6
solute carrier family 39 (metal ion
375
2.4
BB825002




transporter), member 6


A230035L05Rik
Slc41a2
RIKEN cDNA A230035L05 gene
765
2.3
BC026874


Eeg1
Slc43a3
embryonic epithelial gene 1
452
2.2
NM_021398


Slc4a7
Slc4a7
solute carrier family 4, sodium
81
2.2
BB454531




bicarbonate cotransporter, member 7


—
Slc7a1

Mus musculus 7 days neonate
215
2.7
BB264620




cerebellum cDNA, RIKEN full-length




enriched library, clone: A730046J11




product: unclassifiable, full insert




sequence


—
Slc7a1

Mus musculus 7 days neonate
331
2.7
BB264620




cerebellum cDNA, RIKEN full-length




enriched library, clone: A730046J11




product: unclassifiable, full insert




sequence


Slfn2
Slfn2
schlafen 2
190
12.0
NM_011408


Slfn8
Slfn8
schlafen 8
72
8.6
BC024709


Smc2l1
Smc2l1
SMC2 structural maintenance of
16
2.1
BI684556




chromosomes 2-like 1 (yeast)


Smc2l1
Smc2l1
SMC2 structural maintenance of
25
3.4
BI684556




chromosomes 2-like 1 (yeast)


Smc2l1
Smc2l1
SMC2 structural maintenance of
243
5.2
NM_008017




chromosomes 2-like 1 (yeast)


Smc4l1
Smc4l1
SMC4 structural maintenance of
699
3.3
AV172948




chromosomes 4-like 1 (yeast)


—
Smc4l1

Mus musculus transcribed sequence with
56
6.7
BM244144




weak similarity to protein




ref: NP_081764.1 (M. musculus) RIKEN




cDNA 5730493B19 [Mus musculus]


Smc4l1
Smc4l1
SMC4 structural maintenance of
196
4.0
BI665568




chromosomes 4-like 1 (yeast)


Smc4l1
Smc4l1
SMC4 structural maintenance of
243
5.3
BI665568




chromosomes 4-like 1 (yeast)


1110054A24Rik
Smpdl3b
RIKEN cDNA 1110054A24 gene
108
10.0
NM_133888


Snrpa1
Snrpa1
small nuclear ribonucleoprotein
790
2.1
BC013777




polypeptide A′


Snrpb2
Snrpb2
U2 small nuclear ribonucleoprotein B
906
2.2
AW537796


Snrpb2
Snrpb2
U2 small nuclear ribonucleoprotein B
1003
2.4
AV066554


Snx10
Snx10
sorting nexin 10
203
20.8
AK010399


2410003C09Rik
Soat1
RIKEN cDNA 2410003C09 gene
197
3.1
BC025091


—
Socs2
—
75
3.3
BB022048


Socs2
Socs2
suppressor of cytokine signaling 2
478
5.8
NM_007706


Socs2
Socs2
suppressor of cytokine signaling 2
354
5.5
NM_007706


Socs3
Socs3
suppressor of cytokine signaling 3
60
17.5
NM_007707


Socs3
Socs3
suppressor of cytokine signaling 3
153
22.3
BB241535


Socs3
Socs3
suppressor of cytokine signaling 3
98
17.8
BB831725


Solt
Solt
SoxLZ/Sox6 leucine zipper binding
95
3.8
NM_021790




protein in testis


—
Spata5

Mus musculus transcribed sequences
30
2.9
BG069359


Spata5
Spata5
spermatogenesis associated 5
180
2.4
NM_021343


—
Spata5

Mus musculus transcribed sequences
74
2.0
BG074352


Spata5
Spata5
spermatogenesis associated 5
32
5.6
BB819052


Sphk1
Sphk1
sphingosine kinase 1
171
2.1
AF068749


Spib
Spib
Spi-B transcription factor (Spi-1/PU.1
78
2.4
BM244106




related)


Spn
Spn
sialophorin
130
2.3
NM_009259


Spop
Spop
speckle-type POZ protein
45
2.6
AA688828


Spred1
Spred1
sprouty protein with EVH-1 domain 1,
890
2.0
BQ044290




related sequence


Ssb
Ssb
Sjogren syndrome antigen B
427
2.0
BG796845


Ssbp2
Ssbp2
single-stranded DNA binding protein 2
19
1.9
AK005150


BC030940
Ssh2
cDNA sequence BC030940
373
2.1
BB038915


0610038P07Rik
Ssr3
RIKEN cDNA 0610038P07 gene
1890
2.7
AU022074


Stat1
Stat1
signal transducer and activator of
171
23.0
AW214029




transcription 1


—
Stat1

Mus musculus transcribed sequences
85
19.6
BB229853


Stat1
Stat1
signal transducer and activator of
915
14.1
AW214029




transcription 1


Stat1
Stat1
signal transducer and activator of
808
22.7
AW214029




transcription 1


Stat2
Stat2
signal transducer and activator of
145
3.2
AF088862




transcription 2


Stat2
Stat2
signal transducer and activator of
138
6.1
AF088862




transcription 2


Stat3
Stat3
signal transducer and activator of
746
3.3
AK004083




transcription 3


Steap
Steap
six transmembrane epithelial antigen of
391
2.8
AF297098




the prostate


Steap
Steap
six transmembrane epithelial antigen of
176
3.9
AF297098




the prostate


Stk17b
Stk17b
serine/threonine kinase 17b (apoptosis-
240
9.3
AV173139




inducing)


Stk17b
Stk17b
serine/threonine kinase 17b (apoplosis-
364
9.3
AV173139




inducing)


Stk17b
Stk17b
serine/threonine kinase 17b (apoplosis-
70
4.9
AI661948




inducing)


Epb7.2
Stom
erythrocyte protein band 7.2
83
2.4
AF093620


Strm
Strm
striamin
713
3.2
BE853286


Stx11
Stx11
syntaxin 11
59
10.1
AK017897


Sulf1
Sulf1
sulfalase 1
24
3.3
BB751459


Sulf1
Sulf1
sulfalase 1
42
5.3
BB065799


Suv39h1
Suv39h1
suppressor of variegation 3-9 homolog 1
184
3.3
AF193862




(Drosophila)


Suv39h2
Suv39h2
suppressor of variegation 3-9 homolog 2
29
3.1
NM_022724




(Drosophila)


Syk
Syk
spleen tyrosine kinase
39
2.7
U36776


Syk
Syk
spleen tyrosine kinase
98
3.4
AW907526


Syk
Syk
spleen tyrosine kinase
20
11.5
AW907526


Syncrip
Syncrip
synaptotagmin binding, cytoplasmic RNA
303
2.1
BG920261




interacting protein


Syt1
Syt1
synaptotagmin 1
64
2.1
BM118245


Syt13
Syt13
synaptotagmin 13
37
3.3
BB244585


T2bp
T2bp
Traf2 binding protein
317
3.7
BB277065


Tacc3
Tacc3
transforming, acidic coiled-coil containing
47
3.8
BB787809




protein 3


Tank
Tank
TRAF family member-associated Nf-
23
5.5
BB040938




kappa B activator


Tap2
Tap2
transporter 2, ATP-binding cassette, sub-
389
11.2
BE691515




family B (MDR/TAP)


Tapbp
Tapbp
TAP binding protein
917
4.6
AF043943


Tapbp
Tapbp
TAP binding protein
2304
5.5
AF043943


LOC213233
Tapbpl
similar to hypothetical protein FLJ10143
255
7.4
BC017613


LOC213233
Tapbpl
similar to hypothetical protein FLJ10143
36
5.3
BC017613


Tbc1d8
Tbc1d8
TBC1 domain family, member 8
135
2.2
BC005421


Tbk1
Tbk1
TANK-binding kinase 1
546
2.1
NM_019786


Tbx21
Tbx21
T-box 21
19
12.6
NM_019507


Tcerg1
Tcerg1
transcription elongation regulator 1
29
3.7
AW046403




(CA150)


Tcf7
Tcf7
transcription factor 7, T-cell specific
58
13.5
AI323642


—
TCR beta-chain

M. musculus mRNA for Tcell receptor, V-J
22
8.2
M87849




beta junctional region (clone T1CRP8)


—
Tcra

Mus musculus adult male thymus cDNA,
54
2.9
AV312643




RIKEN full-length enriched library,




clone: 5830404G23 product: T-cell




receptor alpha chain precursor V-J region




(TA72) (fragment) homolog [Mus





musculus], full insert sequence


—
Tcra

Mus musculus adult male thymus cDNA,
567
8.8
U95921




RIKEN full-length enriched library,




clone: 5830404G23 product: T-cell




receptor alpha chain precursor V-J region




(TA72) (fragment) homolog [Mus





musculus], full insert sequence


—
Tcra

Mus musculus adult male thymus cDNA,
697
7.7
U07662




RIKEN full-length enriched library,




clone: 5830404G23 product: T-cell




receptor alpha chain precursor V-J region




(TA72) (fragment) homolog [Mus





musculus], full insert sequence


—
Tcra

Mus musculus T cell receptor alpha chain
612
9.2
X01134




variable region (TCRAV3S9) mRNA,




partial cds


—
Tcra

Mus musculus adult male thymus cDNA,
27
7.5
BM243643




RIKEN full-length enriched library,




clone: 5830404G23 product: T-cell




receptor alpha chain precursor V-J region




(TA72) (fragment) homolog [Mus





musculus], full insert sequence


—
Tcrb-J;
—
31
3.1
AK018014



5830405F06Rik


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
21
4.0
U63547


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
68
55.0
U07661


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
22
7.0
AI021643


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
41
75.1
X67128


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
16
4.2
BF318536


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
28
7.5
M31648


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
217
28.7
U46841


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
12
6.8
U46841


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
17
24.4
X14388


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
65
55.9
M11456


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable 13
170
29.2
M16120


Tes
Tes
testis derived transcript
400
2.8
BC010465


Tfdp1
Tfdp1
transcription factor Dp 1
709
2.1
BG075396


Tgfb1i1
Tgfb1i1
transforming growth factor beta 1 induced
268
2.0
NM_009365




transcript 1


Tgfbi
Tgfbi
transforming growth factor, beta induced
294
24.1
NM_009369


—
Tgfbi
—
219
27.0
B8533460


Tgfbi
Tgfbi
transforming growth factor, beta induced
229
19.6
NM_009369


Tgfbi
Tgfbi
transforming growth factor, beta induced
556
6.1
BB532080


—
Tgfbr2

Mus musculus transcribed sequences
105
2.4
BB465968


5730599O09Rik
Tgif2
RIKEN cDNA 5730599O09 gene
93
2.4
AW556273


Tgm2
Tgm2
transglutaminase 2, C polypeptide
4344
2.1
B8550124


Tgm2
Tgm2
transglutaminase 2, C polypeptide
3210
2.7
BB041811


—
Tgn

Mus musculus transcribed sequences
16
5.8
A1451480


Tgtp
Tgtp
T-cell specific GTPase
1220
24.4
NM_011579


Thbs1
Thbs1
thrombospondin 1
337
2.8
AI385532


Thbs1
Thbs1
thrombospondin 1
727
2.7
AI385532


Thbs2
Thbs2
thrombospondin 2
74
2.2
NM_011581


—
Thrap2

Mus musculus transcribed sequences
18
4.5
C79489


Thy1
Thy1
thymus cell antigen 1, theta
53
28.3
AV028402


Timeless
Timeless
timeless homolog (Drosophila)
43
3.1
BM230269


Timeless
Timeless
timeless homolog (Drosophila)
117
3.4
BM230269


Timp1
Timp1
tissue inhibitor of metalloproteinase 1
69
61.5
BC008107


1110005A05Rik
Tipin
RIKEN cDNA 1110005A05 gene
507
2.3
AK011357


Tle4
Tle4
transducin-like enhancer of split 4, E(spl)
208
2.1
AU045006




homolog (Drosophila)


Tlr1
Tlr1
toll-like receptor 1
40
12.4
AF316985


Tlr2
Tlr2
toll-like receptor 2
145
11.9
NM_011905


Tlr3
Tlr3
toll-like receptor 3
252
2.3
NM_126166


Tlr3
Tlr3
toll-like receptor 3
129
3.9
NM_126166


Tlr4
Tlr4
toll-like receptor 4
19
3.1
BB148728


Tlr4
Tlr4
toll-like receptor 4
152
2.3
AF185285


Tlr4
Tlr4
toll-like receptor 4
91
2.2
AF185285


Tlr6
Tlr6
toll-like receptor 6
48
5.4
NM_011604


Tlr7
Tlr7
toll-like receptor 7
16
9.1
AY035889


Tm4sf7
Tm4sf7
transmembrane 4 superfamily member 7
1349
2.0
NM_053082


Tm6sf1
Tm6sf1
transmembrane 6 superfamily member 1
116
5.3
AV378394


Tm6sf1
Tm6sf1
transmembrane 6 superfamily member 1
280
2.8
AV378394


Mtf2
Tmed5
metal response element binding
283
2.0
BG066919




transcription factor 2


Tmod3
Tmod3
tropomodulin 3
447
2.1
BB224629


Tmod3
Tmod3
tropomodulin 3
452
2.1
AK017725


Tmpo
Tmpo
thymopoietin
1030
2.5
AA153892


Tmprss4
Tmprss4
transmembrane protease, serine 4
36
11.7
BC021368


—
Tmsb10

M. musculus mRNA for testis-specific
4515
5.7
AV148480




thymosin beta-10


Tmsb10
Tmsb10
thymosin, beta 10
941
10.4
NM_025284





M. musculus mRNA for testis-specific


—
Tmsb10
thymosin beta-10
1945
7.8
BB096368


Tmsb4x
Tmsb4x
thymosin, beta 4, X chromosome
9065
2.7
NM_021278


Tnfaip2
Tnfaip2
tumor necrosis factor, alpha-induced
749
1.9
NM_009396




protein 2


Tnfaip3
Tnfaip3
tumor necrosis factor, alpha-induced
77
4.8
NM_009397




protein 3


Tnfaip3
Tnfaip3
tumor necrosis factor, alpha-induced
236
4.3
BM241351




protein 3


Abcb1a
Tnfaip9
ATP-binding cassette, sub-family B
95
5.7
NM_054098




(MDR/TAP), member 1A


Tnfrsf11b
Tnfrsf11b
tumor necrosis factor receptor
3
4.0
AB013898




superfamily, member 11b




(osteoprotegerin)


Tnfrsf12a
Tnfrsf12a
tumor necrosis factor receptor
810
2.5
NM_013749




superfamily, member 12a


Tnfrsf12a
Tnfrsf12a
tumor necrosis factor receptor
693
3.0
NM_013749




superfamily, member 12a


Tnfrsf14
Tnfrsf14
tumor necrosis factor receptor
14
10.0
BC022125




superfamily, member 14 (herpesvirus




entry mediator)


Tnfrsf18
Tnfrsf18
tumor necrosis factor receptor
81
5.5
AF229434




superfamily, member 18


Tnfrsf1b
Tnfrsf1b
tumor necrosis factor receptor
182
3.2
M60469




superfamily, member 1b


Tnfrsf4
Tnfrsf4
tumor necrosis factor receptor
163
4.7
NM_011659




superfamily, member 4


Tnfrsf5
Tnfrsf5
tumor necrosis factor receptor
46
18.8
NM_011611




superfamily, member 5


Tnfrsf5
Tnfrsf5
tumor necrosis factor receptor
48
20.4
BB220422




superfamily, member 5


Tnfrsf5
Tnfrsf5
tumor necrosis factor receptor
95
15.7
AI385482




superfamily, member 5


Tnfrsf7
Tnfrsf7
tumor necrosis factor receptor
20
9.6
L24495




superfamily, member 7


Tnfsf10
Tnfsf10
tumor necrosis factor (ligand)
293
5.1
NM_009425




superfamily, member 10


Tnfsf13b
Tnfsf13b
tumor necrosis factor (ligand)
48
3.0
BB079466




superfamily, member 13b


Tnfsf13b
Tnfsf13b
tumor necrosis factor (ligand)
101
7.4
NM_033622




superfamily, member 13b


Tnfsf9
Tnfsf9
tumor necrosis factor (ligand)
29
5.3
NM_009404




superfamily, member 9


Tnip1
Tnip1
TNFAIP3 interacting protein 1
724
2.4
AJ242777


Top2a
Top2a
topoisomerase (DNA) II alpha
39
3.9
BB749838


Top2a
Top2a
topoisomerase (DNA) II alpha
142
14.7
BM211413


2810429C13Rik
Topbp1
RIKEN cDNA 2810429C13 gene
334
2.5
BC007170


Tor3a
Tor3a
torsin family 3, member A
226
2.4
NM_023141


Tor3a
Tor3a
torsin family 3, member A
180
4.1
AK009693


Tor3a
Tor3a
torsin family 3, member A
287
3.3
NM_023141


—
Tox

Mus musculus transcribed sequences
24
4.1
BM124834


Tox
Tox
thymocyte selection-associated HMG box
6
10.5
BB547854




gene


Tox
Tox
thymocyte selection-associated HMG box
89
4.7
BB547854




gene


5430425C04Rik
Tp53i5
RIKEN cDNA 5430425C04 gene
44
3.5
AK017334


Tpm2
Tpm2
tropomyosin 2, beta
307
2.5
BC024358


Tpm2
Tpm2
tropomyosin 2, beta
977
2.2
AK003186


—
Tpm4

Mus musculus 7 days embryo whole
1905
2.9
AV122663




body cDNA, RIKEN full-length enriched




library, clone: C430002D13




product: TROPOMYOSIN 4 homolog




[Homo sapiens], full insert sequence


Tpst1
Tpst1
protein-tyrosine sulfotransferase 1
130
4.8
NM_013837


Tpt1h
Tpt1h
tRNA splicing 2′ phosphotransferase 1
181
16.0
BB113173




homolog (S. cerevisiae)


2610005B21Rik
Tpx2
RIKEN cDNA 2610005B21 gene
132
3.4
AK011311


2610005B21Rik
Tpx2
RIKEN cDNA 2610005B21 gene
9
6.5
AK011311


Traf1
Traf1
Tnf receptor-associated factor 1
40
6.1
BB218245


Traf1
Traf1
Tnf receptor-associated factor 1
34
10.8
BG064103


Trem3
Trem3
triggering receptor expressed on myeloid
96
2.4
NM_021407




cells 3


5031403H21Rik
Treml4
RIKEN cDNA 5031403H21 gene
5
14.6
BB740529


—
Trex1

Mus musculus adult female vagina
26
6.3
AF140709




cDNA, RIKEN full-length enriched library,




clone: 9930022F21 product: similar to G




PROTEIN COUPLED RECEPTOR [Mus





musculus], full insert sequence


Ifld2
Trib3
induced in fatty liver dystrophy 2
34
6.6
BB508622


Trim12
Trim12
tripartite motif protein 12
13
8.3
BM244351


Trim21
Trim21
tripartite motif protein 21
341
2.3
BC010580


Trim21
Trim21
tripartite motif protein 21
325
3.9
BC010580


Trim27
Trim27
tripartite motif protein 27
783
2.2
BB290427


Trim30
Trim30
tripartite motif protein 30
215
7.9
AF220015


Trim30
Trim30
tripartite motif protein 30
252
9.4
BM240719


9230105E10Rik
Trim34
RIKEN cDNA 9230105E10 gene
427
4.5
BI653857


Trip13
Trip13
thyroid hormone receptor interactor 13
31
4.5
AK010336


Trip13
Trip13
thyroid hormone receptor interactor 13
56
9.0
AK010336


Tslpr
Tslpr
thymic stromal-derived lymphopoietin,
313
3.7
NM_016715




receptor


Ttk
Ttk
Ttk protein kinase
30
7.1
NM_009445


Tuba1
Tuba1
tubulin, alpha 1
1848
3.7
NM_011653


Tuba2
Tuba2
tubulin, alpha 2
9060
2.2
BC008117


Tuba8
Tuba8
tubulin, alpha 8
67
2.9
BB047533


Tubb2
Tubb2
tubulin, beta 2
969
2.9
BC003475


Tubb5
Tubb5
tubulin, beta 5
568
3.6
BG064086


Tubb5
Tubb5
tubulin, beta 5
2009
3.3
NM_011655


2310057H16Rik
Tubb6
RIKEN cDNA 2310057H16 gene
204
4.2
NM_026473


Tube1
Tube1
epsilon-tubulin 1
27
2.7
AK010005


Txk
Txk
TXK tyrosine kinase
31
4.2
U19607


Tyki
Tyki
thymidylate kinase family LPS-inducible
406
3.0
AK004595




member


Tyrobp
Tyrobp
TYRO protein tyrosine kinase binding
261
17.8
NM_011662




protein


C330001M22
Ubash3a
hypothetical protein C330001M22
89
3.1
BB397001


Ubd
Ubd
ubiquitin D
121
223.5
NM_023137


Ube2c
Ube2c
ubiquitin-conjugating enzyme E2C
133
10.5
AV162459


Ubce8
Ube2l6
ubiquitin-conjugating enzyme 8
85
8.7
BC008238


Ugcg
Ugcg
UDP-glucose ceramide
203
2.2
BF682223




glucosyltransferase


Ugcg
Ugcg
UDP-glucose ceramide
229
2.5
AA591863




glucosyltransferase


Np95
Uhrf1
nuclear protein 95
60
12.5
BB702754


Np95
Uhrf1
nuclear protein 95
43
6.5
BB702754


2510009H09Rik
Unc5cl
RIKEN cDNA 2510009H09 gene
71
2.5
AK010945


Unc93b
Unc93b1
unc-93 homolog B (C. elegans)
424
3.3
BC018388


Upp1
Upp1
uridine phosphorylase 1
391
8.2
NM_009477


Usp18
Usp18
ubiquitin specific protease 18
165
20.6
NM_011909


—
Usp32

Mus musculus transcribed sequence with
34
2.1
BB740339




weak similarity to protein




ref: NP_081764.1 (M. musculus) RIKEN




cDNA 5730493B19 [Mus musculus]


Vasp
Vasp
vasodilator-stimulated phosphoprotein
705
3.1
BC015289


—
Vcam1

Mus musculus transcribed sequences
49
20.6
AV280637


Vcam1
Vcam1
vascular cell adhesion molecule 1
152
25.4
L08431


1300011C24Rik
Vdp
RIKEN cDNA 1300011C24 gene
3412
2.0
AV139821


Vim
Vim
vimentin
1185
8.9
AV147875


Vim
Vim
vimentin
1376
8.7
M24849


Vim
Vim
vimentin
570
10.5
AV147875


Vps54
Vps54
vacuolar protein sorting 54 (yeast)
8
2.9
BB201271


Vrk1
Vrk1
vaccinia related kinase 1
243
2.0
BC016676


Vrk2
Vrk2
vaccinia related kinase 2
87
3.3
BC013520


Vrk2
Vrk2
vaccinia related kinase 2
154
3.0
AK012664


Wars
Wars
tryptophanyl-tRNA synthetase
387
2.4
BC003450


Wars
Wars
tryptophanyl-tRNA synthetase
791
2.7
BB785450


Wars
Wars
tryptophanyl-tRNA synthetase
193
4.6
AK004541


Wars
Wars
tryptophanyl-tRNA synthetase
768
2.9
AI528863


Was
Was
Wiskott-Aldrich syndrome homolog
25
17.0
NM_009515




(human)


Waspip
Waspip
Wiskott-Aldrich syndrome protein
249
4.9
C76969




interacting protein


Waspip
Waspip
Wiskott-Aldrich syndrome protein
195
4.6
C76969




interacting protein


Wbp5
Wbp5
WW domain binding protein 5
3473
2.1
BC007478


—
Wbscr1

Mus musculus transcribed sequences
43
2.5
BI499987


Wbscr5
Wbscr5
Williams-Beuren syndrome chromosome
67
5.7
AF257136




region 5 homolog (human)


D630024B06Rik
Wdhd1
RIKEN cDNA D630024B06 gene
71
5.0
C77437


Whsc1
Whsc1
Wolf-Hirschhorn syndrome candidate 1
104
2.8
AK017992




(human)


Wisp1
Wisp1
WNT1 inducible signaling pathway
145
2.4
NM_018865




protein 1


2700038M07Rik
Wsb1
RIKEN cDNA 2700038M07 gene
786
2.1
BC019601


Xcl1
Xcl1
chemokine (C motif) ligand 1
32
18.1
NM_008510


Xdh
Xdh
xanthine dehydrogenase
167
16.7
AV286265


Ywhah
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-
2590
2.2
NM_011738




monooxygenase activation protein, eta




polypeptide


Zap70
Zap70
zeta-chain (TCR) associated protein
45
6.2
BB204558




kinase


Zbp1
Zbp1
Z-DNA binding protein 1
49
78.0
AK008179


Zbp1
Zbp1
Z-DNA binding protein 1
14
118.4
NM_021394


Zc3hav1
Zc3hav1
zinc finger CCCH type, antiviral 1
174
2.0
AK004770


Zc3hav1
Zc3hav1
zinc finger CCCH type, antiviral 1
465
4.0
BB757349


Zc3hdc1
Zc3hdc1
zinc finger CCCH type domain containing 1
462
6.7
BM227980


A430104C18Rik
Zc3hdc7
RIKEN cDNA A430104C18 gene
193
2.4
AW556219


2410141K03Rik
Zcchc10
RIKEN cDNA 2410141K03 gene
159
2.1
BC025078


—
Zcchc6

Mus musculus transcribed sequences
113
2.1
BI695361


1110051N18Rik
Zcwcc3
RIKEN cDNA 1110051N18 gene
343
3.5
AI452146


1110051N18Rik
Zcwcc3
RIKEN cDNA 1110051N18 gene
224
3.2
BC026506


—
Zfhx1b

Mus musculus transcribed sequence with
65
2.3
BG061923




moderate similarity to protein sp: P00722




(E. coli) BGAL_ECOLI Beta-




galactosidase (Lactase)


—
Zfhx1b

Mus musculus Corpos mRNA, 3′
59
3.1
BM220939




untranslated region


—
Zfhx1b

Mus musculus transcribed sequences
65
2.3
BB488200


Zfhx1b
Zfhx1b
zinc finger homeobox 1b
226
2.4
NM_015753


Zfp118
Zfp118
Zinc finger protein 118
59
2.2
BB176857


Zfp313
Zfp313
zinc finger protein 313
1410
2.0
BB251247


3732412P20
Zfp455
hypothetical protein 3732412P20
37
3.6
AV172851


Zfp472
Zfp472
zinc finger protein 472
149
2.1
BC023090


Zfp52
Zfp52
zinc finger protein 52
68
2.7
BM225280


Zfp52
Zfp52
zinc finger protein 52
263
2.4
BM225280


Zfp118
Zfp53
Zinc finger protein 118
132
2.3
NM_013843


Znfn1a1
Zfpn1a1
zinc finger protein, subfamily 1A, 1
85
19.8
AV317621




(Ikaros)


—
Zfpn1a1

Mus musculus, clone IMAGE: 1263252,
40
2.6
BM237812




mRNA


Znfn1a3
Zfpn1a3
zinc finger protein, subfamily 1A, 3
42
4.4
BB202216




(Aiolos)


Znfn1a3
Zfpn1a3
zinc finger protein, subfamily 1A, 3
34
21.1
BB151746




(Aiolos)


Zfr
Zfr
zinc finger RNA binding protein
54
2.5
BB214490


Zfr
Zfr
zinc finger RNA binding protein
71
2.6
BM119505


Zipro1
Zipro1
zinc finger proliferation 1
185
3.0
AI326272


B830022L21Rik
Znrf1
RIKEN cDNA B830022L21 gene
190
2.4
BC006765


—
Zswim6

Mus musculus transcribed sequences
116
2.0
AI427602


D10Ertd749e
Zwint
DNA segment, Chr 10, ERATO Doi 749,
143
2.6
BC013559




expressed


Brd7

bromodomain containing 7
14
2.4
BB022341


—


Mus musculus transcribed sequence with
229
2.5
BG143461




strong similarity to protein sp: P00722 (E. coli)




BGAL_ECOLI Beta-galactosidase




(Lactase)


—


Mus musculus transcribed sequences
24
2.9
BB066105


Crsp9

cofactor required for Sp1 transcriptional
59
2.2
AK009549




activation, subunit 9, 33 kDa


—

—
104
2.6
BQ033755


—


Mus musculus transcribed sequences
8
3.1
BE686253


—


Mus musculus 0 day neonate eyeball
40
2.6
BB710625




cDNA, RIKEN full-length enriched library,




clone: E130307M10




product: unclassifiable, full insert




sequence


—


Mus musculus transcribed sequence with
223
3.8
AW556821




weak similarity to protein pir: I58401




(M. musculus) I58401 protein-tyrosine




kinase (EC 2.7.1.112) JAK3 - mouse


—

—
1919
3.2
AY052560


Srrm1

serine/arginine repetitive matrix 1
43
2.5
BB254130


—


Mus musculus adult male aorta and vein
54
2.3
BB224338




cDNA, RIKEN full-length enriched library,




clone: A530086D01 product: unknown




EST, full insert sequence


—

—
78
4.4
BB116018


—


Mus musculus transcribed sequences
37
2.5
BE691393


—


Mus musculus transcribed sequences
57
3.1
BE943672


—


Mus musculus transcribed sequences
12
5.8
BE447255


Loxl2

lysyl oxidase-like 2
231
2.2
AI415741


—


Mus musculus 16 days neonate heart
24
3.1
BB042982




cDNA, RIKEN full-length enriched library,




clone: D830032E20 product: similar to




ENVELOPE PROTEIN (FRAGMENT)




[Friend spleen focus-forming virus], full




insert sequence


Pfkp

phosphofructokinase, platelet
438
2.3
BB076574


Itgb4bp

integrin beta 4 binding protein
174
2.0
AK018313


—


Mus musculus 2 days neonate thymus
102
3.3
BI076809




thymic cells cDNA, RIKEN full-length




enriched library, clone: E430008K23




product: unknown EST, full insert




sequence


—


Mus musculus 12 days embryo
54
2.2
BM239026




embryonic body between diaphragm




region and neck cDNA, RIKEN full-length




enriched library, clone: 9430088I02




product: unknown EST, full insert




sequence


—


Mus musculus adult male thymus cDNA,
5
8.8
BB241847




RIKEN full-length enriched library,




clone: 5830404C02 product: unknown




EST, full insert sequence


—

—
12
2.2
BB800744


Cp

ceruloplasmin
232
2.0
BB332449


—


Mus musculus transcribed sequence with
55
3.5
BG075163




strong similarity to protein sp: Q9NZJ4




(H. sapiens) SACS_HUMAN Sacsin


Etv3

ets variant gene 3
284
2.5
BI456953


Strn3

striatin, calmodulin binding protein 3
114
2.0
BB228907


—


Mus musculus 2 days pregnant adult
61
5.5
BE989616




female ovary cDNA, RIKEN full-length




enriched library, clone: E330027C07




product: weakly similar to ZINC FINGER




PROTEIN 43 (HTF6) [Homo sapiens], full




insert sequence


—


Mus musculus 9 days embryo whole
69
4.3
BF163381




body cDNA, RIKEN full-length enriched




library, clone: D030060F23 product: Mus




musculus U22 snoRNA host gene (UHG)




gene, complete sequence, full insert




sequence


—


Mus musculus transcribed sequences
32
2.6
AV300631


—

—
104
2.7
AV084904


Zfp295

zinc finger protein 295
102
2.2
BB091040


—


Mus musculus transcribed sequences
62
2.3
BB230267


H2afz

H2A histone family, member Z
765
1.9
AV215230


—


Mus musculus similar to FLJ14075
80
2.1
BG071110




protein (LOC217431), mRNA


—


Mus musculus 0 day neonate skin cDNA,
47
2.3
AV233462




RIKEN full-length enriched library,




clone: 4632424N07 product: unknown




EST, full insert sequence


—


Mus musculus adult male thymus cDNA,
55
2.8
AV312603




RIKEN full-length enriched library,




clone: 5830404C02 product: unknown




EST, full insert sequence


—


Mus musculus transcribed sequences
134
2.8
BI466416


—


Mus musculus transcribed sequence with
20
2.8
AI452166




weak similarity to protein




ref: NP_061226.1 (M. musculus) 2-cell-




stage, variable group, member 1; variable




group of 2-cell-stage gene family [Mus





musculus]


1700029I01Rik

RIKEN cDNA 1700029I01 gene
81
3.5
AV047635


—


Mus musculus transcribed sequences
62
5.9
AV247387


—


Mus musculus cDNA clone MGC: 6071
130
3.3
BC022776




IMAGE: 3492410, complete cds


—

—
68
4.0
BB256262


Smc6l1

SMC6 structural maintenance of
43
3.0
BB056038




chromosomes 6-like 1 (yeast)


—


Mus musculus transcribed sequences
63
2.1
BB473548


—


Mus musculus transcribed sequences
36
2.7
AU040162


—


Mus musculus 0 day neonate eyeball
48
2.1
BB541236




cDNA, RIKEN full-length enriched library,




clone: E130112O04 product: unknown




EST, full insert sequence


—

—
6
9.3
BB030365


—


Mus musculus transcribed sequences
79
2.5
BG069527


—

—
8
3.4
AI661342


—


Mus musculus transcribed sequences
229
2.2
BM218086


2210023K21Rik

RIKEN cDNA 2210023K21 gene
125
4.7
BI106821


—

—
94
2.1
BG074662


Igsf6

immunoglobulin superfamily, member 6
23
2.8
AV078837


—


Mus musculus transcribed sequence with
29
2.4
BB449580




weak similarity to protein pir: S12207




(M. musculus) S12207 hypothetical




protein (B2 element) - mouse


Rp2h

retinitis pigmentosa 2 homolog (human)
209
2.2
BF168611


—


Mus musculus transcribed sequences
37
3.9
BE634580


Stk4

serine/threonine kinase 4
1036
2.0
BB141897


Ccr7

chemokine (C—C motif) receptor 7
4
9.9
BB204380


—


Mus musculus adult male thymus cDNA,
28
3.1
BB165850




RIKEN full-length enriched library,




clone: 5830443J22 product: unknown




EST, full insert sequence


—


Mus musculus 0 day neonate eyeball
67
2.1
BB538708




cDNA, RIKEN full-length enriched library,




clone: E130013E11 product: unknown




EST, full insert sequence


—


Mus musculus similar to Elongation factor
154
4.1
AV328340




1-alpha 1 (EF-1-alpha-1) (Elongation




factor 1 A-1) (eEF1A-1) (Elongation




factor Tu) (EF-Tu) (LOC381109), mRNA


2610018G03Rik

RIKEN cDNA 2610018G03 gene
123
2.0
AW556821


—


Mus musculus transcribed sequences
36
3.5
BB208080


—


Mus musculus transcribed sequences
21
3.0
BB271581


Atf4

activating transcription factor 4
398
2.4
AV314773


—


Mus musculus transcribed sequences
52
2.3
BB458874


2610039C10Rik

RIKEN cDNA 2610039C10 gene
113
3.5
AK012762


—


Mus musculus transcribed sequence with
42
2.1
AV372127




moderate similarity to protein




ref: NP_038602.1 (M. musculus) L1




repeat, Tf subfamily, member 18 [Mus





musculus]


—


Mus musculus transcribed sequences
224
3.0
AA266723


—

—
388
2.0
AV368189


E430036I04Rik

RIKEN cDNA E430036I04 gene
85
6.8
BB329408


—

—
98
2.4
BQ266693


Rp2h

retinitis pigmentosa 2 homolog (human)
188
2.2
BF168611


—


Mus musculus similar to DYSKERIN
190
4.4
BB779105




(LOC245474), mRNA


0610025L06Rik

RIKEN cDNA 0610025L06 gene
1362
6.2
AV010467


—


Mus musculus, clone IMAGE: 5066616,
72
3.7
BE373131




mRNA


—


Mus musculus transcribed sequences
21
2.4
BM196689


—

—
157
2.2
BG976607


—


Mus musculus transcribed sequences
9
5.0
BB534560


C330006D17Rik

RIKEN cDNA C330006D17 gene
191
2.4
BB397948


—

—
169
4.7
BG976607


—


Mus musculus transcribed sequence with
96
2.2
BB667685




weak similarity to protein pir: S12207




(M. musculus) S12207 hypothetical




protein (82 element) - mouse


—


Mus musculus transcribed sequences
53
12.1
BM246630


—


Mus musculus transcribed sequence with
29
3.8
AI451538




weak similarity to protein pir: S12207




(M. musculus) S12207 hypothetical




protein (B2 element) - mouse


—

—
299
2.3
BG976607


—


Mus musculus mRNA similar to
33
5.1
BC020118




interferon-inducible GTPase (cDNA clone




MGC: 49532 IMAGE: 3495064), complete




cds


Mll

myeloid/lymphoid or mixed-lineage
128
2.0
AK017541




leukemia


—


Mus musculus transcribed sequences
46
2.5
BG073023


Cp

ceruloplasmin
1596
3.9
BB332449


—


Mus musculus similar to 2-cell-stage,
96
2.1
BG070246




variable group, member 3; 2-cell-stage,




variable group, member 1 (LOC236374),




mRNA


—

—
28
5.3
BC003855


—


Mus musculus similar to Ig delta chain C
29
3.5
BE686052




region, membrane-bound form - mouse




(LOC382646), mRNA


3010033P07Rik

RIKEN cDNA 3010033P07 gene
114
2.5
AK013903


—


Mus musculus transcribed sequences
94
3.6
BB376947


—


Mus musculus transcribed sequences
182
2.8
BB829165


Pscdbp

pleckstrin homology, Sec7 and coiled-coil
1081
3.1
BB503614




domains, binding protein


—

—
1108
2.5
BB145101


Hmmr

hyaluronan mediated motility receptor
82
3.0
X64550




(RHAMM)


—


Mus musculus 0 day neonate thymus
25
3.8
AI840829




cDNA, RIKEN full-length enriched library,




clone: A430110E23 product: unknown




EST, full insert sequence


Nr4a2

nuclear receptor subfamily 4, group A,
23
2.8
BB703394




member 2


Rod1

ROD1 regulator of differentiation 1 (S. pombe)
130
3.4
BB519382


Eif4ebp1

eukaryotic translation initiation factor 4E
393
2.6
AV216412




binding protein 1


—


Mus musculus transcribed sequences
94
2.5
BE634878


—


Mus musculus adult male tongue cDNA,
19
3.3
BG061080




RIKEN full-length enriched library,




clone: 2310050P20 product: unknown




EST, full insert sequence


Col1a1

procollagen, type I, alpha 1
138
5.9
BI794771


—


Mus musculus 18 days pregnant adult
136
2.4
BI082172




female placenta and extra embryonic




tissue cDNA, RIKEN full-length enriched




library, clone: 3830421G02




product: unknown EST, full insert




sequence


—

—
512
2.9
BG976607


—

—
244
3.7
BM941868


—

—
1603
3.3
BF719154


Ncf1

neutrophil cytosolic factor 1
35
15.5
BE370703


—


Mus musculus diabetic nephropathy-
118
58.3
BM241271




related gene 1 mRNA, partial sequence


—


Mus musculus transcribed sequence with
148
6.7
BB160586




moderate similarity to protein pir: A39822




(H. sapiens) A39822 leukosialin precursor -




human


—


Mus musculus transcribed sequences
125
3.9
BB667149


Rrm2

ribonucleotide reductase M2
412
8.2
AV301324


—


Mus musculus transcribed sequences
96
2.4
BM243375


—

—
138
2.1
BI155210


Ddx39

DEAD (Asp-Glu-Ala-Asp) box polypeptide
1234
2.5
AV111502




39


—

—
17
4.6
AV340322


Cp

ceruloplasmin
915
4.3
BB332449


—


Mus musculus transcribed sequence with
91
3.0
BB281100




moderate similarity to protein sp: P00722




(E. coli) BGAL_ECOLI Beta-




galactosidase (Lactase)


—

—
230
5.3
U29539


Gna13

guanine nucleotide binding protein, alpha
1362
2.3
BI662324




13


—


Mus musculus transcribed sequences
66
2.5
AA267568


—


Mus musculus 16 days neonate heart
19
4.3
BB518323




cDNA, RIKEN full-length enriched library,




clone: D830028N22




product: unclassifiable, full insert




sequence


Rp2h

retinitis pigmentosa 2 homolog (human)
202
2.2
BF168611


—


Mus musculus adult male cecum cDNA,
28
4.8
AI506672




RIKEN full-length enriched library,




clone: 9130208D14 product: unknown




EST, full insert sequence


—


Mus musculus transcribed sequences
96
3.3
BB767243


9930027N05Rik

RIKEN cDNA 9930027N05 gene
41
39.3
AI662854


—


Mus musculus transcribed sequence with
35
9.3
BB740904




weak similarity to protein




ref: NP_081764.1 (M. musculus) RIKEN




cDNA 5730493B19 [Mus musculus]


—


Mus musculus transcribed sequences
35
2.6
BM239760


—


Mus musculus transcribed sequence with
68
2.9
BF714880




moderate similarity to protein




ref: NP_081764.1 (M. musculus) RIKEN




cDNA 5730493B19 [Mus musculus]


—


Mus musculus transcribed sequences
110
3.5
BM222853


Cp

ceruloplasmin
838
4.2
BB332449


Ncf1

neutrophil cytosolic factor 1
60
7.0
BE370703


—

—
59
37.3
BE688410


Hn1

hematological and neurological
194
7.9
AV067695




expressed sequence 1


—

—
986
20.1
AV066625


Myadm

myeloid-associated differentiation marker
1120
2.1
BB500055


Vcam1

vascular cell adhesion molecule 1
296
19.2
BB250384


Cugbp2

CUG triplet repeat, RNA binding protein 2
148
6.0
BB667096


—


Mus musculus 3 days neonate thymus
41
40.5
BB207611




cDNA, RIKEN full-length enriched library,




clone: A630020E03 product: unknown




EST, full insert sequence


—


Mus musculus transcribed sequence with
510
2.3
AV216768




strong similarity to protein sp: Q61753




(M. musculus) SERA_MOUSE D-3-




phosphoglycerate dehydrogenase (3-




PGDH) (A10)


Cxcl9

chemokine (C—X—C motif) ligand 9
33
69.4
BI104444


Rod1

ROD1 regulator of differentiation 1 (S. pombe)
138
4.6
BB519382


—

—
19
17.8
BC003855


—


Mus musculus transcribed sequence with
536
3.9
C76675




strong similarity to protein sp: P10660




(H. sapiens) RS6_HUMAN 40S ribosomal




protein S6 (Phosphoprotein NP33)


—


Mus musculus transcribed sequences
28
33.7
BB224524


—


Mus musculus adult male aorta and vein
18
23.4
BE692425




cDNA, RIKEN full-length enriched library,




clone: A530049N04 product: unknown




EST, full insert sequence


—


Mus musculus similar to toll-like receptor
32
15.8
BI655907




(LOC279572), mRNA


—


Mus musculus transcribed sequences
196
3.2
AW543723


—

—
31
17.1
BG072508


Etv3

ets variant gene 3
198
2.1
BI456953


—


Mus musculus transcribed sequences
12
2.3
BF321297


—

—
19
67.1
NM_022429


—


Mus musculus similar to AIM2 protein
15
4.0
BE685969




(LOC383619), mRNA


Cnp1

cyclic nucleotide phosphodiesterase 1
354
6.3
BB251922


—

—
286
2.9
BC004065


Tpm3

tropomyosin 3, gamma
621
3.8
AV311925


2210023K21Rik

RIKEN cDNA 2210023K21 gene
381
5.8
BI106821


—


Mus musculus transcribed sequences
115
61.7
AW111920


—

—
172
12.6
BB668084


—

—
24
7.8
AV247013


—

—
38
29.1
BE688410


—


Mus musculus transcribed sequence with
21
6.6
BB535821




weak similarity to protein




ref: NP_081764.1 (M. musculus) RIKEN




cDNA 5730493B19 [Mus musculus]


Rps3

ribosomal protein S3
138
2.0
BG069767


—


Mus musculus adult male aorta and vein
6
5.5
BB214834




cDNA, RIKEN full-length enriched library,




clone: A530023D22




product: unclassifiable, full insert




sequence


—

—
55
6.8
BB135602


—


Mus musculus, clone IMAGE: 1348774,
11
28.8
AA666504




mRNA


Cnn3

calponin 3, acidic
943
4.2
BB490338


Hrasls3

HRAS like suppressor 3
372
21.7
BB404920


—


Mus musculus similar to surface protein
17
7.5
BE629676




MCA-32 (LOC380732), mRNA


—

Mouse non-productive mRNA for T-cell
6
23.2
NM_011558




receptor gamma V5-J1-C1


G1p2

interferon, alpha-inducible protein
112
16.7
AK019325


Pim1

proviral integration site 1
261
4.9
AI323550


Vcam1

vascular cell adhesion molecule 1
268
39.1
BB250384


1200008O12Rik

RIKEN cDNA 1200008O12 gene
7
6.5
AV126179


—


Mus musculus adult male cortex cDNA,
336
10.9
BB645745




RIKEN full-length enriched library,




clone: B530033B21 product: unknown




EST, full insert sequence


—


Mus musculus transcribed sequences
12
7.8
BB552085


G1p2

interferon, alpha-inducible protein
17
10.3
AK019325


Nfkbia

nuclear factor of kappa light chain gene
1311
4.1
BB096843




enhancer in B-cells inhibitor, alpha
















TABLE 3







Transcripts decreased in GKO D5















WT D5
GKO



Gene Symbol


vs
D5 vs


Affymetrix
Common
Gene Title Affymetrix
NCBA
NCBA
Genbank















BC027231
0610037H22Rik
cDNA sequence BC027231
1.0
0.4
AU051504


0610037M15Rik
0610037M15Rik
RIKEN cDNA 0610037M15
15.6
3.2
BG916808




gene


1110007F12Rik
1110007F12Rik
RIKEN cDNA 1110007F12
3.0
0.6
BC020080




gene


1110013L07Rik
1110013L07Rik
RIKEN cDNA 1110013L07
3.0
1.5
BB765852




gene


1110032F04Rik
1110032F04Rik
RIKEN cDNA 1110032F04
1.3
0.4
BE985708




gene


1200015F23Rik
1200015F23Rik
RIKEN cDNA 1200015F23
1.1
0.5
AK004786




gene


1200015F23Rik
1200015F23Rik
RIKEN cDNA 1200015F23
1.8
0.6
AK004786




gene


1500004A08Rik
1500004A08Rik
RIKEN cDNA 1500004A08
2.3
1.1
BB030508




gene


1700008D07Rik
1700008D07Rik
RIKEN cDNA 1700008D07
0.9
0.4
AK005758




gene


1700012B18Rik
1700012B18Rik
RIKEN cDNA 1700012B18
0.7
0.4
BC022135




gene


—
1700091G21Rik

Mus musculus 16 days
4.3
2.1
BG075562




neonate thymus cDNA,




RIKEN full-length enriched




library, clone: A130042K22




product: unknown EST, full




insert sequence


1810054D07Rik
1810054D07Rik
RIKEN cDNA 1810054D07
5.4
1.9
BB397062




gene


1810054D07Rik
1810054D07Rik
RIKEN cDNA 1810054D07
4.5
2.1
BB259628




gene


1810054D07Rik
1810054D07Rik
RIKEN cDNA 1810054D07
5.0
2.2
AK007856




gene


1810062O14Rik
1810062O14Rik
RIKEN cDNA 1810062O14
7.4
3.5
AV060417




gene


—
2010001M06Rik

Mus musculus adult male
0.9
0.3
BE200030




small intestine cDNA, RIKEN




full-length enriched library,




clone: 2010001M06




product: unknown EST, full




insert sequence


2210019E14Rik
2210019E14Rik
RIKEN cDNA 2210019E14
1.5
0.8
BB771921




gene


2210421G13Rik
2210421G13Rik
RIKEN cDNA 2210421G13
9.3
0.8
AV081797




gene


Elk4
2310011G17Rik
ELK4, member of ETS
0.4
0.2
AW046689




oncogene family


2310047C04Rik
2310047C04Rik
RIKEN cDNA 2310047C04
1.2
0.3
BM231657




gene


2600014C01Rik
2600014C01Rik
RIKEN cDNA 2600014C01
0.6
0.2
BC027339




gene


2610042L04Rik
2610042L04Rik
RIKEN cDNA 2610042L04
5.0
0.9
BM195235




gene


2610042L04Rik
2610042L04Rik
RIKEN cDNA 2610042L04
4.9
0.9
BM195235




gene


2610305D13Rik
2610305D13Rik
RIKEN cDNA 2610305D13
0.7
0.1
AK011986




gene


2610528J11Rik
2610528J11Rik
RIKEN cDNA 2610528J11
0.3
0.1
AK012175




gene


2700007P21Rik
2700007P21Rik
RIKEN cDNA 2700007P21
1.1
0.4
BB552785




gene


LOC217820
2700069A02Rik
hypothetical protein
0.8
0.4
BM198642




LOC217820


2810022L02Rik
2810022L02Rik
RIKEN cDNA 2810022L02
0.9
0.3
BC014764




gene


2810429K17Rik
2810429K17Rik
RIKEN cDNA 2810429K17
0.7
0.2
AK013194




gene


2900024C23Rik
2900024C23Rik
RIKEN cDNA 2900024C23
1.3
0.5
AK013580




gene


4631426E05Rik
4631426E05Rik
RIKEN cDNA 4631426E05
0.2
0.1
BB739558




gene


—
4921504P05Rik
—
0.8
0.4
AK014814


4930402H24Rik
4930402H24Rik
RIKEN cDNA 4930402H24
1.1
0.4
AK015050




gene


4930413O22Rik
4930413O22Rik
RIKEN cDNA 4930413O22
1.1
0.5
NM_026493




gene


—
4930420O11Rik

Mus musculus 4 days
1.8
0.7
BB328498




neonate male adipose cDNA,




RIKEN full-length enriched




library, clone: B430318O09




product: CDNA FLJ33039 FIS,




CLONE THYMU2000369,




MODERATELY SIMILAR TO





MUS MUSCULUS





SYNTROPHIN-ASSOCIATED




SERINE-THREONINE




PROTEIN KINASE MRNA




homolog [. . .


4930422I07Rik
4930422I07Rik
RIKEN cDNA 4930422I07
0.9
0.3
BG068263




gene


—
4930488P18Rik
—
1.4
0.2
AV057155


4930562F07Rik
4930523C07Rik
RIKEN cDNA 4930562F07
1.3
0.6
AV032877




gene


4930550C14Rik
4930550C14Rik
RIKEN cDNA 4930550C14
1.9
0.6
AK016083




gene


—
4930556N09Rik

Mus musculus adult male
1.3
0.5
AK016152




testis cDNA, RIKEN full-




length enriched library,




clone: 4930556N09




product: unclassifiable, full




insert sequence


1810010E01Rik
4930579G22Rik
RIKEN cDNA 1810010E01
1.0
0.4
BI202437




gene


4933409L06Rik
4933409L06Rik
RIKEN cDNA 4933409L06
1.3
0.6
BB645791




gene


—
4933412E12Rik

Mus musculus 13 days
2.2
0.5
AK016788




embryo heart cDNA, RIKEN




full-length enriched library,




clone: D330011B05




product: unknown EST, full




insert sequence


—
4933412E12Rik
—
1.5
0.4
BB265147


4933415L06Rik
4933415L06Rik
RIKEN cDNA 4933415L06
1.0
0.4
AW554226




gene


—
4933417N07Rik

Mus musculus adult male
1.1
0.6
AK016849




testis cDNA, RIKEN full-




length enriched library,




clone: 4933417N07




product: unknown EST, full




insert sequence


—
4933422E07Rik

Mus musculus adult male
1.2
0.6
BE630630




bone cDNA, RIKEN full-length




enriched library,




clone: 9830114D01




product: hypothetical protein,




full insert sequence


5133401N09Rik
5133401N09Rik
RIKEN cDNA 5133401N09
1.9
0.7
BC026742




gene


5830405N20Rik
5830405N20Rik
RIKEN cDNA 5830405N20
2.5
0.8
BB202848




gene


9630005B12Rik
5830411O09Rik
RIKEN cDNA 9630005B12
2.4
0.8
BB431654




gene


AI595338
5830443L24Rik
expressed sequence
75.0
0.4
NM_029509




AI595338


5830458K16Rik
5830458K16Rik
RIKEN cDNA 5830458K16
9.1
1.6
BC024872




gene


5830484A20Rik
5830484A20Rik
RIKEN cDNA 5830484A20
1.2
0.5
BG072319




gene


5830484A20Rik
5830484A20Rik
RIKEN cDNA 5830484A20
4.8
2.0
AW909306




gene


9130002C22Rik
9130002C22Rik
RIKEN cDNA 9130002C22
24.4
6.4
BM243571




gene


9130019I15Rik
9130019I15Rik
RIKEN cDNA 9130019I15
46.3
13.7
AK018636




gene


9130022K13Rik
9130022K13Rik
RIKEN cDNA 9130022K13
5.6
1.3
AK018646




gene


—
9130430L19Rik

Mus musculus adult male
1.5
0.7
AK020296




cecum cDNA, RIKEN full-




length enriched library,




clone: 9130430L19




product: unknown EST, full




insert sequence


9230105E10Rik
9230105E10Rik
RIKEN cDNA 9230105E10
3.6
0.6
BB433710




gene


9330177P20Rik
9330177P20Rik
RIKEN cDNA 9330177P20
1.3
0.6
BB375580




gene


—
9530028C05

Mus musculus adult male
3.9
1.7
BQ175154




testis cDNA, RIKEN full-




length enriched library,




clone: 4921508F21




product: similar to




HISTOCOMPATIBILITY 2,




CLASS II ANTIGEN E BETA




[Mus musculus], full insert




sequence


—
9530028C05

Mus musculus adult male
4.6
2.0
BQ175154




testis cDNA, RIKEN full-




length enriched library,




clone: 4921508F21




product: similar to




HISTOCOMPATIBILITY 2,




CLASS II ANTIGEN E BETA




[Mus musculus], full insert




sequence


A030012M09Rik
A030012M09Rik
RIKEN cDNA A030012M09
0.9
0.4
BB549335




gene


A130015N09Rik
A130015N09Rik
RIKEN cDNA A130015N09
0.5
0.2
AI647939




gene


—
A330042I21Rik

Mus musculus adult male
3.6
0.4
BB187486




spinal cord cDNA, RIKEN full-




length enriched library,




clone: A330042I21




product: unknown EST, full




insert sequence


—
A330042I21Rik

Mus musculus adult male
3.6
0.4
AI645293




spinal cord cDNA, RIKEN full-




length enriched library,




clone: A330042I21




product: unknown EST, full




insert sequence


A530088I07Rik
A530088I07Rik
RIKEN cDNA A530088I07
1.8
0.3
BB637972




gene


A630024B12Rik
A630024B12Rik
RIKEN cDNA A630024B12
1.2
0.3
BB240995




gene


A630077B13Rik
A630077B13Rik
RIKEN cDNA A630077B13
183.1
1.5
BB239429




gene


AA960558
AA960558
expressed sequence
1.4
0.7
BB277078




AA960558


Abca13
Abca13
ATP-binding cassette, sub-
0.9
0.2
BB503961




family A (ABC1), member 13


Abcc2
Abcc2
ATP-binding cassette, sub-
0.4
0.1
NM_013806




family C (CFTR/MRP),




member 2


Acas2
Acas2
acetyl-Coenzyme A
0.3
0.1
NM_019811




synthetase 2 (ADP forming)


Adamts15
Adamts15
a disintegrin-like and
0.3
0.1
AV228731




metalloprotease (reprolysin




type) with thrombospondin




type 1 motif, 15


Agtrap
Agtrap
angiotensin II, type I receptor-
0.8
0.2
NM_009642




associated protein


AI447904
AI447904
expressed sequence
70.3
9.7
BM241008




AI447904


AI447904
AI447904
expressed sequence
26.2
7.6
BM241008




AI447904


—
AI451557

Mus musculus transcribed
24.1
3.1
AV277444




sequences


LOC226691
AI607873
interferon-activatable protein
28.9
9.7
AI607873


AI649392
AI649392
expressed sequence
0.9
0.4
BB496366




AI649392


AI788959
AI788959
expressed sequence
0.7
0.1
BC028826




AI788959


AI848100
AI848100
expressed sequence
0.9
0.4
BB148987




AI848100


Aif1
Aif1
allograft inflammatory factor 1
36.5
9.1
NM_019467


4930502N02Rik
Ak7
RIKEN cDNA 4930502N02
2.5
0.4
AV256298




gene


Akr1c20
Akr1c20
aldo-keto reductase family 1,
8.0
2.0
BC021607




member C20


Akr1c21
Akr1c21
aldo-keto reductase family 1,
0.5
0.1
AW146041




member C21


Aldh1a1
Aldh1a1
aldehyde dehydrogenase
0.5
0.1
NM_013467




family 1, subfamily A1


Aldh1b1
Aldh1b1
aldehyde dehydrogenase 1
2.7
1.2
BC020001




family, member B1


Aldh8a1
Aldh8a1
aldehyde dehydrogenase 8
0.3
0.1
BC013511




family, member A1


2810455B10Rik
Als2cr19
RIKEN cDNA 2810455B10
1.0
0.4
AK008055




gene


Amacr
Amacr
alpha-methylacyl-CoA
0.2
0.0
NM_008537




racemase


—
Ankib1

Mus musculus 16 days
0.9
0.3
BB373816




embryo head cDNA, RIKEN




full-length enriched library,




clone: C130072C03




product: hypothetical protein,




full insert sequence


Apg12l
Apg12l
autophagy 12-like (S. cerevisiae)
0.9
0.4
AK016474


App
App
amyloid beta (A4) precursor
2.3
0.7
AV348729




protein


Arhgap15
Arhgap15
Rho GTPase activating
1.9
0.8
AK018058




protein 15


Arhgap18
Arhgap18
Rho GTPase activating
0.4
0.2
BE307291




protein 18


Arl2bp
Arl2bp
ADP-ribosylation factor-like 2
0.9
0.4
NM_024191




binding protein


1200015K23Rik
Armc8
RIKEN cDNA 1200015K23
1.2
0.5
BE995635




gene


Arts1
Arts1
type 1 tumor necrosis factor
4.8
1.9
NM_030711




receptor shedding




aminopeptidase regulator


Arts1
Arts1
type 1 tumor necrosis factor
4.1
1.2
AV287655




receptor shedding




aminopeptidase regulator


Asb13
Asb13
ankyrin repeat and SOCS
0.8
0.4
AF403041




box-containing protein 13


Asb13
Asb13
ankyrin repeat and SOCS
0.9
0.4
AF403041




box-containing protein 13


A330005H02Rik
Atp11c
RIKEN cDNA A330005H02
0.7
0.2
BB184010




gene


Atp1a3
Atp1a3
ATPase, Na+/K+ transporting,
1.2
0.5
BC020177




alpha 3 polypeptide


Atp6v1e1
Atp6v1e1
ATPase, H+ transporting, V1
0.7
0.4
C85064




subunit E isoform 1


—
AW112010

Mus musculus transcribed
32.5
4.1
BE688358




sequences


B230106I24Rik
B230106I24Rik
RIKEN cDNA B230106I24
0.8
0.3
AV369935




gene


B230106I24Rik
B230106I24Rik
RIKEN cDNA B230106I24
1.0
0.5
AV369935




gene


B2m
B2m
beta-2 microglobulin
11.6
2.0
AA170322


B3galt5
B3galt5
UDP-Gal: betaGlcNAc beta
0.4
0.2
NM_033149




1,3-galactosyltransferase,




polypeptide 5


Bak1
Bak1
BCL2-antagonist/killer 1
2.1
0.5
AF402617


BC005471
BC005471
cDNA sequence BC005471
1.5
0.7
BC005471


BC010462
BC010462
cDNA sequence BC010462
3.5
0.3
BC010462


BC013712
BC013712
cDNA sequence BC013712
12.3
4.1
BB262491


BC014805
BC014805
cDNA sequence BC014805
0.7
0.2
AJ132857


BC022687
BC022687
cDNA sequence BC022687
0.3
0.2
BC022687


BC023105
BC023105
cDNA sequence BC023105
70.3
0.7
BC023105


BC026585
BC026585
cDNA sequence BC026585
0.2
0.1
BC026585


L259
BC028528
L259
4.1
1.8
BC028528


2310015I10Rik
Brd4
RIKEN cDNA 2310015I10
13.8
2.8
BC008532




gene


C1r
C1r
complement component 1, r
9.4
3.8
NM_023143




subcomponent


C1s
C1s
complement component 1, s
12.7
2.8
BC022123




subcomponent


C2
C2
complement component 2
3.5
0.9
NM_013484




(within H-2S)


—
C2
—
4.6
0.9
AV290571


—
C2
—
4.4
1.1
AV227574


C230080I20Rik
C230080I20Rik
RIKEN cDNA C230080I20
0.6
0.2
BB795533




gene


C2ta
C2ta
class II transactivator
13.2
1.6
AF042158


C2ta
C2ta
class II transactivator
10.8
1.5
AF042158


C330005L02Rik
C330005L02Rik
RIKEN cDNA C330005L02
0.9
0.4
BE134115




gene


C6.1A
C6.1A
c6.1a protein
0.9
0.5
AI462244


—
C730040L01Rik

Mus musculus 10 days
1.3
0.2
BB391874




neonate cortex cDNA, RIKEN




full-length enriched library,




clone: A830089I03




product: hypothetical KRAB




box containing protein, full




insert sequence


Car5b
Car5b
carbonic anhydrase 5b,
1.1
0.4
NM_019513




mitochondrial


Card11
Card11
caspase recruitment domain
4.6
2.0
AV095659




family, member 11


Casp1
Casp1
caspase 1
9.4
2.2
BC008152


Casp12
Casp12
caspase 12
3.6
1.7
NM_009808


Casp4
Casp4
caspase 4, apoptosis-related
13.6
6.8
NM_007609




cysteine protease


Cbs
Cbs
cystathionine beta-synthase
0.6
0.1
BC026595


Cbx5
Cbx5
chromobox homolog 5
0.9
0.4
NM_007626




(Drosophila HP1a)


Ccl19
Ccl19
chemokine (C—C motif) ligand
1.8
0.1
NM_011888




19


Ccl21a
Ccl21a
chemokine (C—C motif) ligand
0.9
0.1
NM_011335




21a (serine)


—
Ccl27
—
0.7
0.1
BQ174669


Ccl27
Ccl27
chemokine (C—C motif) ligand
0.6
0.2
NM_011336




27


Ccl28
Ccl28
chemokine (C—C motif) ligand
0.9
0.0
BG867337




28


Ccl28
Ccl28
chemokine (C—C motif) ligand
1.1
0.3
BE196980




28


Ccl28
Ccl28
chemokine (C—C motif) ligand
0.9
0.1
BG867337




28


Ccl5
Ccl5
chemokine (C—C motif) ligand 5
140.5
9.6
NM_013653


Ccl8
Ccl8
chemokine (C—C motif) ligand 8
16.0
6.2
NM_021443


Ccr9
Ccr9
chemokine (C—C motif)
2.1
0.6
NM_009913




receptor 9


Mox2
Cd200
antigen identified by
2.2
1.0
AF004023




monoclonal antibody MRC




OX-2


Cd86
Cd86
CD86 antigen
10.4
4.5
NM_019388


—
Cdca3
—
1.7
0.7
AV352659


Cds1
Cds1
CDP-diacylglycerol synthase 1
2.0
0.9
BI152841


4932437H03
Cenpj
hypothetical protein
1.2
0.6
BG068259




4932437H03


Chpt1
Chpt1
choline phosphotransferase 1
0.5
0.2
BC016251


Clrf
Clec2h; Clrf
C-type lectin related f
0.1
0.0
AK017207


Clic5
Clic5
chloride intracellular channel 5
0.7
0.1
BB610000


Clic5
Clic5
chloride intracellular channel 5
0.8
0.2
AA210377


Clic5
Clic5
chloride intracellular channel 5
1.1
0.2
BB028501


Clrf
Clrf
C-type lectin related f
0.2
0.0
AF350410


Cml5
Cml5
camello-like 5
0.6
0.2
BC024605


Arvcf
Comt
armadillo repeat gene deleted
0.8
0.2
NM_007744




in velo-cardio-facial syndrome


Cpeb4
Cpeb4
cytoplasmic polyadenylation
0.9
0.4
NM_026252




element binding protein 4


—
Cpt2
—
1.1
0.5
AV236319


Csprs
Csprs
component of Sp100-rs
1.4
0.1
NM_033616


Csprs
Csprs
component of Sp100-rs
1.8
0.1
BB148221


2210401K11Rik
Ctbs
RIKEN cDNA 2210401K11
0.6
0.3
BC022594




gene


2210401K11Rik
Ctbs
RIKEN cDNA 2210401K11
0.8
0.4
BC022594




gene


Cxcl10
Cxcl10
chemokine (C—X—C motif)
81.6
3.1
NM_021274




ligand 10


Cxcl11
Cxcl11
chemokine (C—X—C motif)
99.2
3.6
NM_019494




ligand 11


Cxcl9
Cxcl9
chemokine (C—X—C motif)
176.4
0.2
NM_008599




ligand 9


Cxcr3
Cxcr3
chemokine (C—X—C motif)
10.2
2.6
NM_009910




receptor 3


Cybb
Cybb
cytochrome b-245, beta
14.2
5.9
NM_007807




polypeptide


Cyp4v3
Cyp4v3
cytochrome P450, family 4,
3.9
1.8
NM_133969




subfamily v, polypeptide 3


—
D030011O10Rik

Mus musculus transcribed
0.6
0.3
BE994639




sequence with weak




similarity to protein pir: T17242




(H. sapiens) T17242




hypothetical protein




DKFZp586B1417.1 - human




(fragment)


D11Ertd759e
D11Ertd759e
DNA segment, Chr 11,
4.9
1.8
AW556558




ERATO Doi 759, expressed


D11Lgp2e
D11Lgp2e
DNA segment, Chr 11, Lothar
6.1
0.6
NM_030150




Hennighausen 2, expressed


D11Lgp2e
D11Lgp2e
DNA segment, Chr 11 Lothar
10.0
2.3
AF316999




Hennighausen 2, expressed


—
D12Ertd551e

Mus musculus adult male
5.5
2.3
BQ175646




tongue cDNA, RIKEN full-




length enriched library,




clone: 2310058N22




product: unknown EST, full




insert sequence


D12Ertd647e
D12Ertd647e
DNA segment, Chr 12,
5.8
1.8
AW554405




ERATO Doi 647, expressed


D12Ertd647e
D12Ertd647e
DNA segment, Chr 12,
4.1
1.4
BI655075




ERATO Doi 647, expressed


—
D12Ertd771e

Mus musculus 13 days
1.3
0.6
BB392503




embryo male testis cDNA,




RIKEN full-length enriched




library, clone: 6030490B17




product: unknown EST, full




insert sequence


D5Ertd135e
D5Ertd135e
DNA segment, Chr 5, ERATO
0.5
0.3
BB401993




Doi 135, expressed


D7Bwg0421e
D7Bwg0421e
DNA segment, Chr 7,
8.1
2.7
BB667693




Brigham & Women's Genetics




0421 expressed


2210404A22Rik
D8Ertd594e
RIKEN cDNA 2210404A22
0.9
0.3
AK008821




gene


Ddx47
Ddx47
DEAD (Asp-Glu-Ala-Asp) box
0.4
0.1
BB305306




polypeptide 47


Defcr9
Defcr9
defensin related cryptdin 9
1.4
0.5
U03065


Dnase1l3
Dnase1l3
deoxyribonuclease 1-like 3
6.4
0.4
BC012671


Dnase1l3
Dnase1l3
deoxyribonuclease 1-like 3
8.8
0.9
BC012671


D14Wsu89e
Dock9
DNA segment, Chr 14,
0.6
0.2
BB795072




Wayne State University 89,




expressed


Dsg2
Dsg2
desmoglein 2
1.9
0.9
C79957


Dsg2
Dsg2
desmoglein 2
1.3
0.6
AB072269


—
Dtx3l

Mus musculus transcribed
9.1
2.1
AV327407




sequence with weak




similarity to protein




ref: NP_081764.1




(M. musculus) RIKEN cDNA




5730493B19 [Mus musculus]


E130309F12Rik
E130309F12Rik
RIKEN cDNA E130309F12
0.7
0.0
BB523550




gene


E430019B13Rik
E430019B13Rik
RIKEN cDNA E430019B13
2.2
0.9
BE630983




gene


1300018P11Rik
Eif4e3
RIKEN cDNA 1300018P11
5.1
2.4
BC027014




gene


2810013J18Rik
Eme2
RIKEN cDNA 2810013J18
1.0
0.4
AK012738




gene


Entpd5
Entpd5
ectonucleoside triphosphate
0.4
0.2
NM_007647




diphosphohydrolase 5


Entpd5
Entpd5
ectonucleoside triphosphate
0.4
0.2
NM_007647




diphosphohydrolase 5


Entpd5
Entpd5
ectonucleoside triphosphate
0.4
0.2
AF136571




diphosphohydrolase 5


Entpd5
Entpd5
ectonucleoside triphosphate
0.5
0.2
NM_007647




diphosphohydrolase 5


2310046K10Rik
Epsti1
RIKEN cDNA 2310046K10
13.4
3.8
AK017174




gene


Etv1
Etv1
ets variant gene 1
0.4
0.1
NM_007960


2610104C07Rik
Exosc1
RIKEN cDNA 2610104C07
1.2
0.6
BC024423




gene


Fabp7
Fabp7
fatty acid binding protein 7,
5.2
0.3
NM_021272




brain


1110064L07Rik
Fbxw17
RIKEN cDNA 1110064L07
4.8
2.3
AV016303




gene


Fcrl3
Fcrl3
Fc receptor-like 3
20.5
5.4
BC027310


Fgl2
Fgl2
fibrinogen-like protein 2
28.1
3.9
BF136544


Fgl2
Fgl2
fibrinogen-like protein 2
46.7
5.6
BF136544


1110008K06Rik
Fln29
RIKEN cDNA 1110008K06
4.0
1.6
AK003586




gene


Fmo4
Fmo4
flavin containing
0.4
0.0
AF461145




monooxygenase 4


Fmo5
Fmo5
flavin containing
0.3
0.1
NM_010232




monooxygenase 5


Fmr1
Fmr1
fragile X mental retardation
1.2
0.6
AF461114




syndrome 1 homolog


6030440G05Rik
Frmd4b
RIKEN cDNA 6030440G05
0.7
0.3
BM119551




gene


—
Gabra2

Mus musculus transcribed
0.9
0.4
BB433285




sequences


A530057M15Rik
Galm
RIKEN cDNA A530057M15
0.6
0.3
AV307219




gene


Gbp2
Gbp2
guanylate nucleotide binding
53.4
2.3
BE197524




protein 2


Gbp2
Gbp2
guanylate nucleotide binding
100.2
2.9
NM_010260




protein 2


Gbp3
Gbp4
guanylate nucleotide binding
42.9
7.5
NM_018734




protein 3


Gca
Gca
grancalcin
1.2
0.5
BC021450


Gca
Gca
grancalcin
1.5
0.4
BC021450


Ghr
Ghr
growth hormone receptor
0.5
0.2
M33324


Ian1
Gimap4
immune associated
3.0
1.1
BC005577




nucleotide 1


Ian1
Gimap4
immune associated
2.4
0.9
BC005577




nucleotide 1


Ian3
Gimap7
immune associated
14.1
5.4
BC026200




nucleotide 3


Glipr1
Glipr1
GLI pathogenesis-related 1
14.8
7.4
BC025083




(glioma)


Gnb4
Gnb4
guanine nucleotide binding
2.1
1.0
BI713933




protein, beta 4


Gpr1
Gpr1
G protein-coupled receptor 1
1.2
0.5
AW541072


Gpr18
Gpr18
G protein-coupled receptor 18
9.9
3.4
BG145550


1810036L03Rik
Gsdmdc1
RIKEN cDNA 1810036L03
6.5
2.5
AK007710




gene


Gstt2
Gstt2
glutathione S-transferase,
0.7
0.3
BC012707




theta 2


Gzmk
Gzmk
granzyme K
14.1
3.9
AB032200


H28
H28
histocompatibility 28
1.6
0.5
NM_031367


H28
H28
histocompatibility 28
6.8
1.1
BC024930


H28
H28
histocompatibility 28
8.9
1.1
NM_031367


—
H2-Aa
—
46.1
10.5
AV086906


H2-Ab1
H2-Ab1
histocompatibility 2, class II
13.2
4.0
NM_010379




antigen A, beta 1


H2-BI
H2-BI
histocompatibility 2,
1.6
0.5
NM_008199




blastocyst


H2-D1
H2-D1
histocompatibility 2, D region
6.2
0.0
NM_010380




locus 1


H2-DMb1
H2-DMb1
histocompatibility 2, class II,
19.8
3.8
NM_010387




locus Mb1


H2-DMb1
H2-DMb1
histocompatibility 2, class II,
38.0
4.3
NM_010388




locus Mb1


H2-DMb1
H2-DMb1
histocompatibility 2, class II,
45.2
4.8
BB734586




locus Mb1


H2-K
H2-K1
histocompatibility 2, K region
22.5
7.1
L23495


—
H2-K1
MHC I = H-2Kd homolog
45.5
10.8
S70184




{alternatively spliced, deletion




of exon 3} [mice, DBA/2,




L1210 lymphoma, mRNA




Mutant, 855 nt]


H2-M3
H2-M3
histocompatibility 2, M region
4.8
2.0
NM_013819




locus 3


H2-Oa
H2-Oa
histocompatibility 2, O region
6.1
1.4
NM_008206




alpha locus


H2-Ob
H2-Ob
histocompatibility 2, O region
4.4
1.1
BG144448




beta locus


H2-Q1
H2-Q1
histocompatibility 2, Q region
22.6
3.1
BC010602




locus 1


H2-Q7
H2-Q7
histocompatibility 2, Q region
78.5
24.8
M29881




locus 7


H2-T10
H2-T10
histocompatibility 2, T region
4.3
0.7
NM_010395




locus 10


H2-T23
H2-T23
histocompatibility 2, T region
8.0
0.9
NM_010398




locus 23


—
H2-T23

Mus musculus 2 days
6.6
1.3
NM_010398




neonate thymus thymic cells




cDNA, RIKEN full-length




enriched library,




clone: C920026N01




product: weakly similar to H-2




CLASS I




HISTOCOMPATIBILITY




ANTIGEN, D-37 ALPHA




CHAIN PRECURSOR [Mus





musculus], full insert




sequence


H2-T24
H2-T24
histocompatibility 2, T region
3.1
0.6
L22338




locus 24


Hadhsc
Hadhsc
L-3-hydroxyacyl-Coenzyme A
0.4
0.1
BB114220




dehydrogenase, short chain


Hdc
Hdc
histidine decarboxylase
0.9
0.1
BG072171


Hdc
Hdc
histidine decarboxylase
0.9
0.1
AF109137


Helic1
Helic1
helicase, ATP binding 1
1.4
0.6
BB501662


2510038N07Rik
Herc5
RIKEN cDNA 2510038N07
20.4
1.2
AI639807




gene


2510038N07Rik
Herc5
RIKEN cDNA 2510038N07
18.0
2.0
AK015214




gene


2510038N07Rik
Herc5
RIKEN cDNA 2510038N07
12.8
1.0
AI639807




gene


2510038N07Rik
Herc5
RIKEN cDNA 2510038N07
25.4
1.9
AW208668




gene


—
Hk3
—
14.9
4.0
BB324660


—
Hnrpm

Mus musculus transcribed
0.9
0.4
AW493461




sequences


Hpse
Hpse
heparanase
22.8
11.4
BG094050


Hrasls3
Hrasls3
HRAS like suppressor 3
16.5
0.8
BC024581


Hsd11b1
Hsd11b1
hydroxysteroid 11-beta
0.3
0.2
NM_008288




dehydrogenase 1


Hsf2bp
Hsf2bp
heat shock transcription factor
0.6
0.2
AK016553




2 binding protein


Icsbp1
Icsbp1
interferon consensus
9.9
2.8
BG069095




sequence binding protein 1


Icsbp1
Icsbp1
interferon consensus
10.0
3.7
BG069095




sequence binding protein 1


Idh1
Idh1
isocitrate dehydrogenase 1
0.8
0.3
AI788952




(NADP+), soluble


Ifi1
Ifi1
interferon inducible protein 1
15.4
1.1
NM_008326


Ifi202b
Ifi202b
interferon activated gene
42.5
5.8
AV229143




202B


Ifi202b
Ifi202b
interferon activated gene
46.5
3.2
NM_011940




202B


Ifi203
Ifi203
interferon activated gene 203
17.8
8.8
NM_008328


Ifi203
Ifi203
interferon activated gene 203
9.1
2.7
BC008167


Ifi16
Ifi204
interferon, gamma-inducible
24.8
5.5
NM_008329




protein 16


Ifi205
Ifi205
interferon activated gene 205
151.7
40.3
M74124


Ifi205
Ifi205
interferon activated gene 205
102.7
10.1
AI481797


Ifi205
Ifi205
interferon activated gene 205
79.7
13.6
AI481797


2010008K16Rik
Ifi35
RIKEN cDNA 2010008K16
4.5
1.7
BC008158




gene


2010008K16Rik
Ifi35
RIKEN cDNA 2010008K16
6.0
2.3
AW986054




gene


A430056A10Rik
Ifi44
RIKEN cDNA A430056A10
5.0
0.7
BB329808




gene


9130009C22Rik
Ifih1
RIKEN cDNA 9130009C22
5.4
1.7
AY075132




gene


Ifit1
Ifit1
interferon-induced protein
18.5
3.5
NM_008331




with tetratricopeptide repeats 1


Ifit2
Ifit2
interferon-induced protein
33.8
2.0
NM_008332




with tetratricopeptide repeats 2


Ifit3
Ifit3
interferon-induced protein
6.3
0.6
NM_010501




with tetratricopeptide repeats 3


Ifng
Ifng
interferon gamma
30.3
2.5
K00083


Igf1
Igf1
insulin-like growth factor 1
2.7
1.1
NM_010512


Igf1
Igf1
insulin-like growth factor 1
2.0
0.9
BG075165


Igh-6
Igh-6
immunoglobulin heavy chain
6.0
1.9
AI326478




6 (heavy chain of IgM)


Igk-V1
Igk-V1
immunoglobulin kappa chain
1.4
0.2
U29768




variable 1 (V1)


Igk-V8
Igk-V8
immunoglobulin kappa chain
1.5
0.2
BI107286




variable 8 (V8)


Igsf7
Igsf7
immunoglobulin superfamily,
7.0
3.4
AF251705




member 7


Igtp
Igtp
interferon gamma induced
25.9
0.8
NM_018738




GTPase


—
Igtp

Mus musculus 13 days
14.3
1.0
BB485297




embryo lung cDNA, RIKEN




full-length enriched library,




clone: D430030N05




product: unknown EST, full




insert sequence


AI481100
Igtp
expressed sequence
30.9
1.2
NM_019440




AI481100


AW111922
Iigp1
expressed sequence
36.6
0.6
BM239828




AW111922


AW111922
Iigp1
expressed sequence
53.7
0.7
BM239828




AW111922


Il12b
Il12b
interleukin 12b
1.7
0.3
AF128214


Il12rb1
Il12rb1
interleukin 12 receptor, beta 1
5.5
2.6
NM_008353


Il15
Il15
interleukin 15
1.0
0.2
NM_008357


Il18
Il18
interleukin 18
2.1
0.9
NM_008360


Il18bp
Il18bp
interleukin 18 binding protein
33.6
1.5
AF110803


Temt
Inmt
thioether S-methyltransferase
0.2
0.0
NM_009349


B430217B02Rik
Irf1
RIKEN cDNA B430217B02
15.7
2.2
NM_008390




gene


Irf7
Irf7
interferon regulatory factor 7
9.8
2.9
NM_016850


Irg1
Irg1
immunoresponsive gene 1
80.3
31.1
L38281


Itga4
Itga4
integrin alpha 4
8.5
3.3
NM_010576


Itm2a
Itm2a
integral membrane protein 2A
1.1
0.5
BI966443


Itm2a
Itm2a
integral membrane protein 2A
1.0
0.4
BI966443


Itpka
Itpka
inositol 1,4,5-trisphosphate 3-
1.7
0.9
BC027291




kinase A


Klra2
Klra2
killer cell lectin-like receptor,
14.3
2.5
NM_008462




subfamily A, member 2


Klra7
Klra7
killer cell lectin-like receptor,
7.9
1.8
U10095




subfamily A, member 7


Klra8
Klra8
killer cell lectin-like receptor,
5.5
0.9
U12889




subfamily A, member 8


Klra3
Klra9
killer cell lectin-like receptor,
6.5
1.9
U49865




subfamily A, member 3


Klrb1d
Klrb1d
killer cell lectin-like receptor
4.6
1.3
AF342896




subfamily B member 1D


Klrb1d
Klrb1d
killer cell lectin-like receptor
9.8
3.3
NM_008526




subfamily B member 1D


Klrc1
Klrc1
killer cell lectin-like receptor
19.3
7.6
AF106009




subfamily C, member 1


Klrk1
Klrk1
killer cell lectin-like receptor
21.5
3.5
AF039026




subfamily K, member 1


D7Bwg0421e
Lair1
DNA segment, Chr 7,
11.9
4.0
AK017222




Brigham & Women's Genetics




0421 expressed


—
Leprel1

Mus musculus 12 days
0.9
0.4
BB105009




embryo embryonic body




between diaphragm region




and neck cDNA, RIKEN full-




length enriched library,




clone: 9430093N11




product: unknown EST, full




insert sequence


Letm1
Letm1
leucine zipper-EF-hand
0.6
0.3
BG060855




containing transmembrane




protein 1


Lgals8
Lgals8
lectin, galactose binding,
1.1
0.5
AI987967




soluble 8


—
Lmtk2

Mus musculus transcribed
1.2
0.3
BB449235




sequence with strong




similarity to protein sp: P00722




(E. coli) BGAL_ECOLI Beta-




galactosidase (Lactase)


LOC207685
LOC207685
hypothetical protein
2.7
0.5
AK008551




LOC207685


LOC209387
LOC209387
tripartite motif protein 30-like
20.2
7.5
BM241342


LOC223672
LOC223672
hypothetical protein
25.0
0.7
BC020489




LOC223672


Ly6c
Ly6c
lymphocyte antigen 6
2.8
1.0
NM_010741




complex, locus C


Ly6i
Ly6i
lymphocyte antigen 6
15.4
0.4
AF232024




complex, locus I


Ly86
Ly86
lymphocyte antigen 86
24.1
11.6
NM_010745


2410018D16Rik
Mat2b
RIKEN cDNA 2410018D16
1.0
0.5
NM_134017




gene


—
MDABG2-4

Mus musculus nucleosome-
2.0
0.6
AB007986




reactive monoclonal antibody




PR1-3, Ig light chain variable




region mRNA, partial cds.


Mgat3
Mgat3
mannoside
0.2
0.1
NM_010795




acetylglucosaminyltransferase 3


MGC25972
MGC25972
similar to cytochrome P450,
0.4
0.1
BC025936




4a10


Mia2
Mia2
melanoma inhibitory activity 2
0.9
0.3
AF390177


—
Mpa2l

Mus musculus transcribed
72.1
1.7
BG092512




sequences


—
Mpa2l

Mus musculus transcribed
118.4
1.5
BM241485




sequence with weak




similarity to protein sp: P32456




(H. sapiens) GBP2_HUMAN




Interferon-induced guanylate-




binding protein 2 (Guanine




nucleotide-binding protein 2)


Mpeg1
Mpeg1
macrophage expressed gene 1
22.7
6.9
L20315


Ms4a1
Ms4a1
membrane-spanning 4-
4.0
2.0
BB236617




domains, subfamily A,




member 1


Ms4a4b
Ms4a4b
membrane-spanning 4-
56.0
11.5
BB199001




domains, subfamily A,




member 4B


Ms4a4d
Ms4a4d
membrane-spanning 4-
12.6
0.7
NM_025658




domains, subfamily A,




member 4D


Ms4a6b
Ms4a6b
membrane-spanning 4-
45.7
15.7
NM_027209




domains, subfamily A,




member 6B


Ms4a6c
Ms4a6c
membrane-spanning 4-
14.8
5.8
AF237910




domains, subfamily A,




member 6C


Mtac2d1
Mtac2d1
membrane targeting (tandem)
0.4
0.1
BB548141




C2 domain containing 1


Mtap7
Mtap7
microtubule-associated
1.2
0.6
AK006385




protein 7


Mx1
Mx1
myxovirus (influenza virus)
6.9
1.8
M21039




resistance 1


—
Net1

Mus musculus transcribed
4.1
1.2
AV247312




sequences


Ngfr
Ngfr
nerve growth factor receptor
8.3
3.1
BB151515




(TNFR superfamily, member




16)


Nmi
Nmi
N-myc (and STAT) interactor
6.7
1.4
BC002019


Nt5c2
Nt5c2
5′-nucleotidase, cytosolic II
1.1
0.4
BI202534


Nt5c2
Nt5c2; GMP;
5′-nucleotidase, cytosolic II
1.6
0.7
BC006028



NT5B; PNT5;



cN-II;



2010002I23Rik


Oas1g
Oas1a
2′-5′ oligoadenylate
6.9
2.4
BC018470




synthetase 1G


Oasl2
Oasl2
2′-5′ oligoadenylate
17.4
1.9
BQ033138




synthetase-like 2


Og9x
Og9x
OG9 homeobox gene
0.7
0.4
BB705267


BC047207
Olfml1
cDNA sequence BC047207
0.7
0.3
BB055163


Olfr56
Olfr56
olfactory receptor 56
39.5
2.3
NM_008330


A130090K04Rik
Oprm1
RIKEN cDNA A130090K04
1.3
0.4
BB703415




gene


A130090K04Rik
Oprm1
RIKEN cDNA A130090K04
3.1
1.1
BQ176089




gene


Osbpl6
Osbpl6
oxysterol binding protein-like 6
0.5
0.2
BG070848


Paip1
Paip1
polyadenylate binding protein-
0.8
0.1
BB381990




interacting protein 1


Paip1
Paip1
polyadenylate binding protein-
0.9
0.0
BC019726




interacting protein 1


5330431N24Rik
Parp11
RIKEN cDNA 5330431N24
3.1
1.3
BB026163




gene


BC021340
Parp14
cDNA sequence BC021340
16.1
3.0
BC021340


Adprtl3
Parp3
ADP-ribosyltransferase
2.6
0.8
BC014870




(NAD+; poly (ADP-ribose




polymerase)-like 3


Adprtl3
Parp3
ADP-ribosyltransferase
2.1
1.0
AW990611




(NAD+; poly (ADP-ribose




polymerase)-like 3


BC003281
Parp9
cDNA sequence BC003281
12.0
2.9
NM_030253


1110035O14Rik
Pbef1
RIKEN cDNA 1110035O14
2.4
1.0
AW989410




gene


Pclo
Pclo
piccolo (presynaptic
0.6
0.1
AW493746




cytomatrix protein)


Pdcd1lg1
Pdcd1lg1
programmed cell death 1
45.1
4.7
NM_021893




ligand 1


Pde9a
Pde9a
phosphodiesterase 9A
0.6
0.3
NM_008804


Pdzk1
Pdzk1; Pdzd1;
PDZ domain containing 1
0.4
0.2
AK006269



mPDZK1;



D3Ertd537e;



1700023D20Rik;



2610507N21Rik;



4921513F16Rik


Peli1
Peli1
pellino 1
2.1
1.0
BC016515


4933417L10Rik
Phf11
RIKEN cDNA 4933417L10
4.8
1.1
AV280841




gene


Phip
Phip
pleckstrin homology domain
1.3
0.5
BI737352




interacting protein


Pigr
Pigr
polymeric immunoglobulin
4.4
1.7
AV027632




receptor


Pigr
Pigr
polymeric immunoglobulin
3.0
1.2
NM_011082




receptor


—
Pink1
—
0.4
0.2
AV371921


—
Plec1

Mus musculus similar to
1.4
0.5
BI525140




Plec1 protein (LOC381010),




mRNA


Pnp
Pnp
purine-nucleoside
2.2
0.8
AK008143




phosphorylase


Mt1a
Polr2k
metallothionein-I activator
0 9
0.4
AA175187


Ppargc1
Ppargc1a
peroxisome proliferative
0.5
0.2
BB745167




activated receptor, gamma,




coactivator 1


—
Ppt1

Mus musculus 12 days
3.0
0.6
BB461203




embryo spinal ganglion




cDNA, RIKEN full-length




enriched library,




clone: D130070K05




product: unknown EST, full




insert sequence


Ppt1
Ppt1
palmitoyl-protein thioesterase 1
1.0
0.5
AF326558


Prkr
Prkr
protein kinase, interferon-
5.0
2.0
BE911144




inducible double stranded




RNA dependent


—
Prok1

Mus musculus 3 days
0.6
0.3
BE651535




neonate thymus cDNA,




RIKEN full-length enriched




library, clone: A630076J17




product: unclassifiable, full




insert sequence


Psmb10
Psmb10
proteasome (prosome,
14.7
3.6
NM_013640




macropain) subunit, beta type




10


Psmb8
Psmb8
proteosome (prosome,
27.5
4.1
NM_010724




macropain) subunit, beta type




8 (large multifunctional




protease 7)


Psmb8
Psmb8
proteosome (prosome,
24.0
3.4
AV068122




macropain) subunit, beta type




8 (large multifunctional




protease 7)


Psmb9
Psmb9
proteosome (prosome,
30.2
2.1
NM_013585




macropain) subunit, beta type




9 (large multifunctional




protease 2)


Tap1
Psmb9
transporter 1, ATP-binding
29.5
3.9
AW048052




cassette, sub-family B




(MDR/TAP)


Psme1
Psme1
proteasome (prosome,
3.1
1.5
NM_011189




macropain) 28 subunit, alpha


Psme2
Psme2
proteasome (prosome,
5.3
1.9
NM_011190




macropain) 28 subunit, beta


Psme4
Psme4
proteasome (prosome,
0.8
0.3
BG075584




macropain) activator subunit 4


—
Ptbp2

Mus musculus 16 days
1.3
0.6
BB155176




neonate thymus cDNA,




RIKEN full-length enriched




library, clone: A130023P20




product: unclassifiable, full




insert sequence


Ptprcap
Ptprcap
protein tyrosine phosphatase,
7.5
3.5
NM_016933




receptor type, C polypeptide-




associated protein


—
Ptprk

Mus musculus transcribed
1.0
0.4
BG802688




sequences


2410027J01Rik
Qprt
RIKEN cDNA 2410027J01
0.6
0.1
AI195046




gene


—
Rab11fip3

Mus musculus 0 day neonate
0.4
0.2
BQ266518




kidney cDNA, RIKEN full-




length enriched library,




clone: D630036H09




product: similar to EFERIN




[Homo sapiens], full insert




sequence


Rab17
Rab17
RAB17, member RAS
0.6
0.3
NM_008998




oncogene family


Rab19
Rab19
RAB19, member RAS
2.8
0.9
BM241400




oncogene family


Rbl1
Rbl1
retinoblastoma-like 1 (p107)
5.8
2.2
U27177


—
Rkhd2

Mus musculus 16 days
0.8
0.2
BB369687




embryo head cDNA, RIKEN




full-length enriched library,




clone: C130049H14




product: unknown EST, full




insert sequence


4930474F22Rik
Rnase10
RIKEN cDNA 4930474F22
1.2
0.3
AK015573




gene


Rnaset2
Rnaset2;
ribonuclease T2
2.2
0.6
AK015947



RNASE6PL;



0610007O07Rik;



4833423A10Rik;



4930532K22Rik


Samhd1
Samhd1
SAM domain and HD domain, 1
16.3
5.3
AV376100


Samhd1
Samhd1
SAM domain and HD domain, 1
11.4
4.1
BF148012


Samhd1
Samhd1
SAM domain and HD domain, 1
11.3
2.7
NM_018851


D11Moh48
Scrn2
DNA segment, Chr 11, KL
0.3
0.1
BC021346




Mohlke 48


D11Moh48
Scrn2
DNA segment, Chr 11, KL
0.3
0.1
BB735480




Mohlke 48


Sec8
Sec8l1
SEC8 (S. cerevisiae)
0.9
0.4
AK010695


Sectm1
Sectm1
secreted and transmembrane 1
3.0
0.0
AI481997


Sell
Sell
selectin, lymphocyte
14.0
6.5
M36005


Sell
Sell
selectin, lymphocyte
9.7
4.7
M36005


Serpina10
Serpina10
serine (or cysteine)
44.0
17.5
BC018416




proteinase inhibitor, clade A




(alpha-1 antiproteinase,




antitrypsin), member 10


Sfrp1
Sfrp1
secreted frizzled-related
0.5
0.2
BI658627




sequence protein 1


Sfrp1
Sfrp1
secreted frizzled-related
0.5
0.2
BI658627




sequence protein 1


Sgcb
Sgcb
sarcoglycan, beta (dystrophin-
0.9
0.3
AK014381




associated glycoprotein)


Slamf7
Slamf7
SLAM family member 7
5.4
1.1
AK016183


Slamf8
Slamf8
SLAM family member 8
65.9
9.5
BC024587


1200003C15Rik
Slc16a9
RIKEN cDNA 1200003C15
0.3
0.1
AK004684




gene


1200003C15Rik
Slc16a9
RIKEN cDNA 1200003C15
0.4
0.1
AK004684




gene


Slc18a1
Slc18a1
solute carrier family 18
0.3
0.1
BB011871




(vesicular monoamine),




member 1


Slc1a1
Slc1a1
solute carrier family 1,
0.5
0.2
AF087578




member 1


Slc1a4
Slc1a4
solute carrier family 1
1.8
0.6
BB277461




(glutamate/neutral amino acid




transporter), member 4


Slc1a4
Slc1a4
solute carrier family 1
1.5
0.6
BB277461




(glutamate/neutral amino acid




transporter), member 4


Slc22a5
Slc22a5
solute carrier family 22
0.4
0.2
NM_011396




(organic cation transporter),




member 5


Slc26a7
Slc26a7
solute carrier family 26,
0.5
0.2
AV292356




member 7


Slc2a5
Slc2a5
solute carrier family 2
0.2
0.0
NM_019741




(facilitated glucose




transporter), member 5


A230035L05Rik
Slc41a2
RIKEN cDNA A230035L05
2.3
1.0
BC026874




gene


AI315119
Slc5a12
expressed sequence
0.3
0.1
BB503566




AI315119


Xtrp2
Slc6a18
X transporter protein 2
0.7
0.3
AF075266


4632401C08Rik
Slc6a19
RIKEN cDNA 4632401C08
0.4
0.1
AK014544




gene


4632401C08Rik
Slc6a19
RIKEN cDNA 4632401C08
0.4
0.1
BM119683




gene


Slco1a1
Slco1a1
solute carrier organic anion
0.2
0.0
AB031813




transporter family, member




1a1


Slfn8
Slfn8
schlafen 8
8.6
2.7
BC024709


Smpdl3a
Smpdl3a
sphingomyelin
0.6
0.2
NM_020561




phosphodiesterase, acid-like




3A


Snx10
Snx10
sorting nexin 10
20.8
8.4
AK010399


Sod3
Sod3
superoxide dismutase 3,
0.3
0.1
NM_011435




extracellular


Sostdc1
Sostdc1
sclerostin domain containing 1
0.4
0.2
BC021458


Srd5a2l
Srd5a2l
steroid 5 alpha-reductase 2-
1.1
0.4
BB825787




like


—
Ss18

Mus musculus transcribed
1.1
0.5
BB199855




sequences


—
Stat1

Mus musculus transcribed
19.6
1.4
BB229853




sequences


Stat1
Stat1
signal transducer and
22.7
1.1
AW214029




activator of transcription 1


Stat1
Stat1
signal transducer and
14.1
1.1
AW214029




activator of transcription 1


Stat1
Stat1
signal transducer and
23.0
2.0
AW214029




activator of transcription 1


Stat2
Stat2
signal transducer and
6.1
1.7
AF088862




activator of transcription 2


Stat2
Stat2
signal transducer and
3.2
1.3
AF088862




activator of transcription 2


4921538B17Rik
Steap2
RIKEN cDNA 4921538B17
1.2
0.5
BB529332




gene


Mrpl16
Stx3
mitochondrial ribosomal
0.6
0.1
D29800




protein L16


Sult1c1
Sult1c2
sulfotransferase family,
0.5
0.2
NM_026935




cytosolic, 1C, member 1


Syn2
Syn2
synapsin II
0.3
0.1
NM_013681


Syt1
Syt1
synaptotagmin 1
2.1
0.9
BM118245


Tap2
Tap2
transporter 2, ATP-binding
11.2
2.5
BE691515




cassette, sub-family B




(MDR/TAP)


Tapbp
Tapbp
TAP binding protein
4.6
1.0
AF043943


Tapbp
Tapbp
TAP binding protein
5.5
2.1
AF043943


LOC213233
Tapbpl
similar to hypothetical protein
5.3
1.5
BC017613




FLJ10143


4432405K22Rik
Tbc1d15
RIKEN cDNA 4432405K22
1.2
0.6
BF577643




gene


Tcf7
Tcf7
transcription factor 7, T-cell
13.5
4.5
AI323642




specific


—
TCR beta-chain

M. musculus mRNA for Tcell
8.2
2.4
M87849




receptor, V-J beta junctional




region (clone T1CRP8)


—
Tcra

Mus musculus T cell receptor
9.2
3.9
X01134




alpha chain variable region




(TCRAV3S9) mRNA, partial




cds


—
Tcra

Mus musculus adult male
7.7
3.0
U07662




thymus cDNA, RIKEN full-




length enriched library,




clone: 5830404G23 product: T-




cell receptor alpha chain




precursor V-J region (TA72)




(fragment) homolog [Mus





musculus], full insert




sequence


—
Tcra

Mus musculus adult male
1.7
0.7
BB032962




thymus cDNA, RIKEN full-




length enriched library,




clone: 5830474E17 product: T-




cell receptor alpha chain




precursor V-J region (TA72)




(fragment) homolog [Mus





musculus], full insert




sequence


—
Tcrb-J;
—
3.1
0.5
AK018014



5830405F06Rik


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable
55.0
25.2
U07661




13


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable
55.9
21.5
M11456




13


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable
6.8
1.0
U46841




13


Tcrb-V13
Tcrb-V13
T-cell receptor beta, variable
75.1
29.5
X67128




13


Tex9
Tex9
testis expressed gene 9
1.3
0.4
AK008505


—
Tgfbr2

Mus musculus transcribed
2.4
0.6
BB465968




sequences


Tgtp
Tgtp
T-cell specific GTPase
24.4
1.7
NM_011579


Timp3
Timp3
tissue inhibitor of
0.5
0.2
BI111620




metalloproteinase 3


Syn2
Timp4
synapsin II
0.5
0.2
AK013810


Tlr3
Tlr3
toll-like receptor 3
3.9
1.2
NM_126166


1810015P03Rik
Tmed6
RIKEN cDNA 1810015P03
0.5
0.2
NM_025458




gene


2810428F02Rik
Tmem19
RIKEN cDNA 2810428F02
0.8
0.4
AK018383




gene


Tmprss4
Tmprss4
transmembrane protease,
11.7
2.0
BC021368




serine 4


Tnfrsf14
Tnfrsf14
tumor necrosis factor receptor
10.0
0.9
BC022125




superfamily, member 14




(herpesvirus entry mediator)


Tnfrsf5
Tnfrsf5
tumor necrosis factor receptor
15.7
4.4
AI385482




superfamily, member 5


Tnfrsf5
Tnfrsf5
tumor necrosis factor receptor
18.8
7.6
NM_011611




superfamily, member 5


Tnfrsf5
Tnfrsf5
tumor necrosis factor receptor
20.4
6.6
BB220422




superfamily, member 5


Tnfsf10
Tnfsf10
tumor necrosis factor (ligand)
5.1
0.4
NM_009425




superfamily, member 10


Top2b
Top2b
topoisomerase (DNA) II beta
1.8
0.6
BB166592


5430425C04Rik
Tp53i5
RIKEN cDNA 5430425C04
3.5
1.2
AK017334




gene


—
Trex1

Mus musculus adult female
6.3
2.9
AF140709




vagina cDNA, RIKEN full-




length enriched library,




clone: 9930022F21




product: similar to G PROTEIN




COUPLED RECEPTOR [Mus





musculus], full insert




sequence


Trim12
Trim12
tripartite motif protein 12
8.3
2.5
BM244351


Trim21
Trim21
tripartite motif protein 21
2.3
1.0
BC010580


Trim21
Trim21
tripartite motif protein 21
3.9
1.1
BC010580


Trim25
Trim25
tripartite motif protein 25
1.2
0.5
AI746456


Trim30
Trim30
tripartite motif protein 30
7.9
2.8
AF220015


9230105E10Rik
Trim34
RIKEN cDNA 9230105E10
4.5
1.7
BI653857




gene


Gtl6
Trip12
gene trap locus 6
0.9
0.4
BG923744


E130308C19Rik
Tspyl5
RIKEN cDNA E130308C19
1.6
0.4
AV332105




gene


Tuba8
Tuba8
tubulin, alpha 8
2.9
1.0
BB047533


Tyki
Tyki
thymidylate kinase family
1.9
0.5
AK004595




LPS-inducible member


C330001M22
Ubash3a
hypothetical protein
3.1
1.3
BB397001




C330001M22


Ubd
Ubd
ubiquitin D
223.5
3.3
NM_023137


Ubce8
Ube2l6
ubiquitin-conjugating enzyme 8
8.7
1.2
BC008238


—
Ubr1

Mus musculus transcribed
0.9
0.4
AV299235




sequence with weak




similarity to protein




pir: RGECDW (E. coli)




RGECDW transcription




activator of D-serine




dehydratase —Escherichia coli


Ugt8
Ugt8
UDP-glucuronosyltransferase 8
0.5
0.2
NM_011674


Upb1
Upb1
ureidopropionase, beta
0.4
0.1
NM_133995


Upp1
Upp1
uridine phosphorylase 1
8.2
2.1
NM_009477


Usp18
Usp18
ubiquitin specific protease 18
20.6
1.6
NM_011909


Wars
Wars
tryptophanyl-tRNA synthetase
2.4
0.9
BC003450


Wars
Wars
tryptophanyl-tRNA synthetase
2.7
0.8
BB785450


—
Wld
—
0.8
0.3
AF260924


Wrn
Wrn
Werner syndrome homolog
1.6
0.5
D86527




(human)


Xdh
Xdh
xanthine dehydrogenase
16.7
6.1
AV286265


—
Ywhaq

Mus musculus 16 days
1.3
0.5
AV024540




neonate thymus cDNA,




RIKEN full-length enriched




library, clone: A130046D12




product: 14-3-3 PROTEIN




TAU (14-3-3 PROTEIN




THETA), full insert sequence


Zbp1
Zbp1
Z-DNA binding protein 1
78.0
3.9
AK008179


Zbp1
Zbp1
Z-DNA binding protein 1
118.4
3.0
NM_021394


9430083K24Rik
Zbtb5
RIKEN cDNA 9430083K24
1.3
0.6
AI267092




gene


Zc3hdc1
Zc3hdc1
zinc finger CCCH type
6.7
2.2
BM227980




domain containing 1


Zfp287
Zfp287
zinc finger protein 287
1.4
0.6
BI714160


AI839779
Zfp365
expressed sequence
0.5
0.2
AV327248




AI839779


Zfp386
Zfp386
zinc finger protein 386
1.8
0.8
NM_019565




(Kruppel-like)


4633401C23Rik
Zfp84
RIKEN cDNA 4633401C23
1.3
0.6
AI465811




gene


Znfn1a3
Zfpn1a3
zinc finger protein, subfamily
4.4
1.9
BB202216




1A, 3 (Aiolos)


Zfr
Zfr
zinc finger RNA binding
2.6
1.0
BM119505




protein


—


Mus musculus similar to 2-
2.1
0.9
BG070246




cell-stage, variable group,




member 3; 2-cell-stage,




variable group, member 1




(LOC236374), mRNA


—

—
0.4
0.2
AK016021


—

—
9.3
3.4
BB030365


—

—
6.8
0.6
BB135602


—


Mus musculus transcribed
0.7
0.2
BG071026




sequences


2210023K21Rik

RIKEN cDNA 2210023K21
4.7
2.3
BI106821




gene


—

—
3.6
1.5
AV340322


—


Mus musculus transcribed
1.3
0.2
BB738659




sequences


—


Mus musculus transcribed
0.3
0.1
BM054266




sequence with moderate




similarity to protein




ref: NP_114409.1 (H. sapiens)




hypothetical protein




MGC1314 similar to




fucosidase, alpha-L-1, tissue




[Homo sapiens]


Vcam1

vascular cell adhesion
19.2
8.8
BB250384




molecule 1


—


Mus musculus anti-MUC1
1.5
0.5
AY058911




antibody SM3 Ig heavy chain




variable region mRNA, partial




cds


—


Mus musculus LOC380741
1.6
0.5
BB323723




(LOC380741), mRNA


—


Mus musculus cDNA clone
0.8
0.2
BB553937




IMAGE: 5151706, partial cds


—


Mus musculus transcribed
1.5
0.1
BG862223




sequence with moderate




similarity to protein




pir: A47643 (M. musculus)




A47643 hypothetical protein -




mouse (fragment)


—


Mus musculus adult male
1.6
0.7
BB022773




pituitary gland cDNA, RIKEN




full-length enriched library,




clone: 5330412J20




product: unknown EST, full




insert sequence


—

—
1.4
0.3
BG065699


—


Mus musculus 0 day neonate
1.5
0.7
AV251099




head cDNA, RIKEN full-length




enriched library,




clone: 4833429G05




product: unknown EST, full




insert sequence


—


Mus musculus transcribed
1.1
0.5
BB378649




sequences


—


Mus musculus similar to
1.9
0.7
AW123234




transmembrane protein




SHREW1 (LOC230959),




mRNA


—


Mus musculus transcribed
0.8
0.3
AV370837




sequence with strong




similarity to protein sp: P00722




(E. coli) BGAL_ECOLI Beta-




galactosidase (Lactase)


—

—
0.6
0.2
AW319988


—


Mus musculus 0 day neonate
0.5
0.2
BB750877




kidney cDNA, RIKEN full-




length enriched library,




clone: D630022F07




product: hypothetical protein,




full insert sequence


—


Mus musculus cDNA clone
3.3
0.8
BC022776




MGC: 6071 IMAGE: 3492410,




complete cds


—

Mouse non-productive mRNA
2.1
0.6
NM_011558




for T-cell receptor gamma V5-




J1-C1


—

—
67.1
8.6
NM_022429


—


Mus musculus transcribed
0.7
0.3
AW124641




sequence with strong




similarity to protein sp: P00722




(E. coli) BGAL_ECOLI Beta-




galactosidase (Lactase)


—


Mus musculus transcribed
1.5
0.3
BB436326




sequence with moderate




similarity to protein




ref: NP_079184.1 (H. sapiens)




hypothetical protein FLJ12973




[Homo sapiens]


—


Mus musculus transcribed
1.1
0.1
C77501




sequence with weak




similarity to protein




ref: NP_443092.1 (H. sapiens)




kruppel-like zinc finger protein




[Homo sapiens]


—


Mus musculus transcribed
1.2
0.4
BB201888




sequence with moderate




similarity to protein




pir: R5HU35 (H. sapiens)




R5HU35 ribosomal protein




L35a —human


—


Mus musculus transcribed
1.4
0.6
BB343967




sequences


Rnaset2

ribonuclease T2
1.7
0.8
AV101824


—


Mus musculus diabetic
58.3
13.4
BM241271




nephropathy-related gene 1




mRNA, partial sequence


—


Mus musculus transcribed
0.7
0.3
BE979870




sequences


—


Mus musculus transcribed
5.0
1.2
BB534560




sequences


—


Mus musculus transcribed
1.1
0.4
AV230978




sequences


Cxcl9

chemokine (C—X—C motif)
69.4
0.7
BI104444




ligand 9


—


Mus musculus adult male
5.5
2.6
BB214834




aorta and vein cDNA, RIKEN




full-length enriched library,




clone: A530023D22




product: unclassifiable, full




insert sequence


Nalp6

NACHT, leucine rich repeat
0.6
0.2
BB071996




and PYD containing 6


—


Mus musculus 9 days embryo
1.1
0.5
BB442202




whole body cDNA, RIKEN




full-length enriched library,




clone: D030030M01




product: unknown EST, full




insert sequence


—


Mus musculus transcribed
61.7
0.4
AW111920




sequences


Clic5

chloride intracellular channel 5
0.9
0.2
BB236747


—


Mus musculus adult male
10.9
1.4
BB645745




cortex cDNA, RIKEN full-




length enriched library,




clone: B530033B21




product: unknown EST, full




insert sequence


—

—
1.5
0.1
BG297038


G1p2

interferon, alpha-inducible
16.7
3.0
AK019325




protein


—


Mus musculus adult male
1.4
0.5
AV254764




testis cDNA, RIKEN full-




length enriched library,




clone: 4921513I01




product: unknown EST, full




insert sequence


—

—
12.6
1.0
BB668084


—

—
17.1
0.5
BG072508


—


Mus musculus mRNA similar
5.1
0.7
BC020118




to interferon-inducible




GTPase (cDNA clone




MGC: 49532




IMAGE: 3495064), complete




cds


—


Mus musculus adult male
0.9
0.1
BB428710




hippocampus cDNA, RIKEN




full-length enriched library,




clone: C630020O05




product: unknown EST, full




insert sequence


—


Mus musculus 0 day neonate
1.5
0.7
BB313276




eyeball cDNA, RIKEN full-




length enriched library,




clone: E130009O20




product: unknown EST, full




insert sequence


—


Mus musculus adult male
2.3
0.3
BB224338




aorta and vein cDNA, RIKEN




full-length enriched library,




clone: A530086D01




product: unknown EST, full




insert sequence


Hrasls3

HRAS like suppressor 3
21.7
1.0
BB404920


—

—
4.6
0.8
AV340322
















TABLE 4







GRIT expression in WT and GKO grafts













ISO D5
ISO D5 vs
WT D5


Gene Symbol
Gene Title Affymetrix
vs NCBA
ISO.GKO D5
vs NCBA














Iigp1
interferon inducible GTPase 1
27.5
8.1
45.7


Tgtp
T-cell specific GTPase
16.6
8.1
28.4


Mpa2l
macrophage activation 2 like
14.9
12.5
92.9


Gbp2
guanylate nucleotide binding protein 2
12.8
33.2
47.7


Gbp2
guanylate nucleotide binding protein 2
11.5
8.6
76.1


Iigp1
interferon inducible GTPase 1
11.2
7.4
20.4


Igtp
interferon gamma induced GTPase
9.3
4.8
17.8


Cxcl10
chemokine (C—X—C motif) ligand 10
7.0

100.9


H2-DMb1
histocompatibility 2, class II, locus
6.5
2.6
11.3



Mb1


Gtpi-pending
interferon-g induced GTPase
5.8
5.0
24.7


Ubd
ubiquitin D
5.3
4.5
91.8


Psmb8
proteosome (prosome, macropain)
4.8
2.0
25.5



subunit, beta type 8 (large



multifunctional protease 7)


Stat1
signal transducer and activator of
3.9
3.3
11.7



transcription 1


Cxcl9
chemokine (C—X—C motif) ligand 9
3.7
14.7
99.8


Mpeg1
macrophage expressed gene 1
3.6

16.4


Psmb9
proteosome (prosome, macropain)
3.6
3.9
19.1



subunit, beta type 9 (large



multifunctional protease 2)


H2-DMb2
histocompatibility 2, class II, locus
3.4
6.3
13.3



Mb2


Psmb10
proteasome (prosome, macropain)
3.4
3.0
14.5



subunit, beta type 10


Ifi1
interferon inducible protein 1
3.1
3.9
8.2


Ifi47
interferon gamma inducible protein
3.1
3.7
21.4


Brd4
bromodomain containing 4
3.0

9.4


Ifit2
interferon-induced protein with
2.8
2.1
25.1



tetratricopeptide repeats 2


Pdcd1lg1
programmed cell death 1 ligand 1
2.7
4.5
29.6


Fgl2
fibrinogen-like protein 2
2.7

14.4


5033415K03Rik
RIKEN cDNA 5033415K03 gene
2.7

17.5


Il18bp
interleukin 18 binding protein
2.6
6.6
17.3


Stat1
signal transducer and activator of
2.6
7.1
7.7



transcription 1


H2-K
histocompatibility 2, K region
2.6
4.7
9.0


Xdh
xanthine dehydrogenase
2.6

11.7


Pigr
polymeric immunoglobulin receptor
2.4

6.5


Parp14
poly (ADP-ribose) polymerase family,
2.4
2.7
11.4



member 14


Ccl5
chemokine (C—C motif) ligand 5
2.4
62.5
34.8


BE688358NCBI
ESTs
2.2
3.5
16.0


5830458K16Rik
RIKEN cDNA 5830458K16 gene
2.2
2.1
9.2


H2-T23
histocompatibility 2, T region locus 23
2.2
2.7
7.3


Arts1-pending
type 1 tumor necrosis factor receptor
2.1

2.8



shedding aminopeptidase regulator


C2ta
class II transactivator
2.1
3.8
7.7


Fabp7
fatty acid binding protein 7, brain
2.1

2.8


G1p2
interferon, alpha-inducible protein
2.1

8.0


Oasl2
2′-5′ oligoadenylate synthetase-like 2
1.9

14.7


Ms4a6b
membrane-spanning 4-domains,
1.9

14.1



subfamily A, member 6B


Tapbp
TAP binding protein
1.9
2.4
4.6


H2-Ab1
histocompatibility 2, class II antigen
1.9
5.0
5.9



A, beta 1


Ms4a4d
membrane-spanning 4-domains,
1.8

3.8



subfamily A, member 4D


Zbp1
Z-DNA binding protein 1
1.8
2.9
12.2


C1s
complement component 1, s
1.7

12.7



subcomponent


Lair1
leukocyte-associated Ig-like receptor 1
1.7

3.3


Ccl8
chemokine (C—C motif) ligand 8
1.6
3.1
3.1


Slamf8
Slamf8
1.6
3.4
15.4


H2-T10
histocompatibility 2, T region locus 10
1.6

3.5


Serpina10
hypothetical protein MGC25863
1.5

8.8


H2-K
histocompatibility 2, K region
1.5
2.1
14.5


Irf7
interferon regulatory factor 7
1.4

6.4


C1r
complement component 1, r
1.3

7.4



subcomponent


Ifit1
interferon-induced protein with
1.3
4.2
5.9



tetratricopeptide repeats 1


Ube1l
Ube1l
1.2

4.2


Hrasls3
HRAS like suppressor 3
1.0

7.2


C2
complement component 2 (within
0.8

3.1



H-2S)


B2m
Beta-2 microglobulin
0.8

5.5
















TABLE 5







GRIT-like transcript expression in WT and GKO grafts













ISO D5

WT D5




vs
ISO D5 vs
vs


Gene Symbol
Gene Title Affymetrix
NCBA
ISO.GKO
NCBA














H2-Aa
histocompatibility 2, class II antigen A,
5.1
3.8
10.8



alpha


Ms4a6d
membrane-spanning 4-domains,
4.0

21.2



subfamily A, member 6D


Hist1h2ad
histone 1, H2ad
3.4

32.4


H2-DMa
histocompatibility 2, class II, locus DMa
3.4
3.6
11.3


Top2a
topoisomerase (DNA) II alpha
3.4

8.5


H2-Aa
histocompatibility 2, class II antigen A,
3.3
3.0
6.8



alpha


Ii
Ia-associated invariant chain
3.1
3.5
5.5


Ctss
cathepsin S
2.9

8.9


Tgfbi
transforming growth factor, beta
2.9

17.3



induced, 68 kDa


Ccr5
chemokine (C—C motif) receptor 5
2.5

12.1


H2-Eb1
histocompatibility 2, class II antigen E
2.5
3.5
6.8



beta


C1qb
complement component 1, q
2.3

8.7



subcomponent, beta polypeptide


Ifi27
interferon, alpha-inducible protein 27
2.2

3.2


Tgfbi
transforming growth factor, beta
2.2

17.2



induced, 68 kDa


Coro1a
coronin, actin binding protein 1A
2.1

35.2


C1qg
complement component 1, q
2.1

8.8



subcomponent, gamma polypeptide


Coro1a
coronin, actin binding protein 1A
2.0

55.3


Gzma
granzyme A
1.9
2.7
4.6


Hck
hemopoietic cell kinase
1.8

7.0


Ppicap
peptidylprolyl isomerase C-associated
1.7

4.8



protein


Serping1
serine (or cysteine) proteinase inhibitor,
1.7

4.3



clade G, member 1


Itgax
integrin alpha X
1.5
2.0
5.9


Was
Wiskott-Aldrich syndrome homolog
1.4

5.9



(human)


Tmsb10
thymosin, beta 10
1.4

6.3


Tgfbi
transforming growth factor, beta
1.4

14.0



induced, 68 kDa


Tmsb10
thymosin, beta 10
1.4

4.1


Epsti1
epithelial stromal interaction 1 (breast)
1.4

7.6


Ly6f
lymphocyte antigen 6 complex, locus F
1.3

2.6


Ifitm3
interferon induced transmembrane
1.3

2.4



protein 3


Ifitm6
interferon induced transmembrane
1.3

2.6



protein 6


AW413625
expressed sequence AW413625
1.2
2.3
3.7


Tnfsf13b
tumor necrosis factor (ligand)
1.2

2.8



superfamily, member 13b


AU020206

Mus musculus 3 days neonate thymus
1.2

5.1



cDNA, RIKEN full-length enriched



library, clone: A630040D01


Ifitm1
interferon induced transmembrane
1.2
2.4
2.5



protein 1


AI132321

Mus musculus 0 day neonate thymus
1.1
2.3
5.1



cDNA, RIKEN full-length enriched



library, clone: A430098J23


Gpm6b
glycoprotein m6b
1.1

2.3


Cugbp2
CUG triplet repeat, RNA binding protein 2
0.9

3.5


Emr4
EGF-like module containing, mucin-like,
0.9

3.0



hormone receptor-like sequence 4


Cxcl14
chemokine (C—X—C motif) ligand 14
0.8

3.0


Socs2
suppressor of cytokine signaling 2
0.8

2.2


9230117N10Rik
RIKEN cDNA 9230117N10 gene
0.7

3.8


Cxcl14
chemokine (C—X—C motif) ligand 14
0.4

7.6
















TABLE 6







Transcripts decreased in GKO D5 but not induced by rIFNγ













ISO D5

WT D5




vs
ISO D5 vs
vs


Gene Symbol
Title_Affy
NCBA
ISO.GKO
NCBA














5830443L24Rik
RIKEN cDNA 5830443L24 gene
8.1
6.8
74.8


BC023105
cDNA sequence BC023105
7.5
20.0
10.9


Cxcl11
chemokine (C—X—C motif) ligand 11
5.8
2.5
70.4


Ifi202b
interferon activated gene 202B
4.9

33.1


Ly86
lymphocyte antigen 86
3.4

12.9


Dnr12
Diabetic nephropathy-like protein (Dnr12)
3.1
3.2
20.4



mRNA, partial sequence


Ubce8
ubiquitin-conjugating enzyme 8
3.0

5.7


H2-D1
histocompatibility 2, D region locus 1
3.0
5.1
7.7


Trim34
tripartite motif protein 34
3.0

9.9


Aif1
allograft inflammatory factor 1
2.8

16.5


Klra2
killer cell lectin-like receptor, subfamily A,
2.7

7.3



member 2


Ptprcap
protein tyrosine phosphatase, receptor
2.4

15.9



type, C polypeptide-associated protein


Ms4a4c
membrane-spanning 4-domains,
2.4
3.2
14.0



subfamily A, member 4C


H28
histocompatibility 28
2.3

6.5


BC013712
cDNA sequence BC013712
2.2
2.4
7.1


Ms4a6c
membrane-spanning 4-domains,
2.2

7.3



subfamily A, member 6C


H28
Histocompatibility 28
2.2

4.4


H2-Q1
histocompatibility 2, Q region locus 1
2.1
5.8
10.9


Tnfrsf5
tumor necrosis factor receptor
2.1
2.6
6.7



superfamily, member 5


Ifi205
interferon activated gene 205
2.1
3.6
25.4


Vcam1
vascular cell adhesion molecule 1
2.1
2.4
12.5


Sell
selectin, lymphocyte
2.0

7.8


Tap2
transporter 2, ATP-binding cassette, sub-
1.9
2.9
7.4



family B (MDR/TAP)


Icsbp
interferon concensus sequence binding
1.9

8.4



protein


Nmi
N-myc (and STAT) interactor
1.9

5.4


Tnfsf10
tumor necrosis factor (ligand)
1.8

6.7



superfamily, member 10


Gbp4
guanylate nucleotide binding protein 4
1.8

12.6


Parp9
poly (ADP-ribose) polymerase family,
1.7
2.3
8.7



member 9


Ifi205
interferon activated gene 205
1.7
3.3
15.9


Casp1
caspase 1
1.7

6.6


Irf1
interferon regulatory factor 1
1.7
2.5
8.7


Igh-6
immunoglobulin heavy chain 6 (heavy
1.7
2.2
4.2



chain of IgM)


Ifit3
interferon-induced protein with
1.7

5.4



tetratricopeptide repeats 3


Casp11
caspase 11, apoptosis-related cysteine
1.7

8.4



protease (caspase 4 precursor)


Usp18
ubiquitin specific protease 18
1.7

8.5


Zc3hdc1
hypothetical protein 9930021O16
1.7

5.2


Samhd1
SAM domain and HD domain, 1
1.7

8.5


Fcrl3
Fc receptor-like 3
1.7

6.6


Oas1g
2′-5′ oligoadenylate synthetase 1G
1.6

3.3


Snx10
sorting nexin 10
1.6

14.0


0610037M15Rik
RIKEN cDNA 0610037M15 gene
1.6

6.4


Ifi203
interferon activated gene 203
1.6

5.7


Stat2
signal transducer and activator of
1.6

4.4



transcription 2


Gzmk
granzyme K
1.6

2.5


Ifi44
interferon-induced protein 44
1.5

4.2


IFNg
interferon gamma
1.5

8.2


Slamf6
SLAM family member 6
1.5

2.2


H2-Q7
histocompatibility 2, Q region locus 7
1.5
3.3
11.2


Il12rb1
interleukin 12 receptor, beta 1
1.5

4.6


Ifi35
interferon-induced protein 35
1.5

4.2


Trim30
tripartite motif protein 30
1.5

4.4


Cybb
cytochrome b-245, beta polypeptide
1.5

5.1


H2-M3
histocompatibility 2, M region locus 3
1.5

4.4


Glipr1
GLI pathogenesis-related 1 (glioma)
1.4

5.6


Slfn8
schlafen 8
1.4

3.0


Ifih1
interferon induced with helicase C
1.4

3.5



domain 1


Trim21
tripartite motif protein 21
1.4

3.0


Trim21
tripartite motif protein 21
1.4

2.3


Stat2
signal transducer and activator of
1.4

8.5



transcription 2


Parp3
poly (ADP-ribose) polymerase family,
1.3

4.4



member 3


2610042L04Rik
RIKEN cDNA 2610042L04 gene
1.3

4.7


H2-T24
histocompatibility 2, T region locus 24
1.3

2.5


Slc41a2
solute carrier family 41, member 2
1.3

3.2


Sectm1
secreted and transmembrane 1
1.3

3.2


Gimap7
GTPase, IMAP family member 7
1.3
2.7
6.0


Cyp4v3
cytochrome P450, family 4, subfamily v,
1.3

2.0



polypeptide 3


Psme2
proteasome (prosome, macropain) 28
1.3

4.2



subunit, beta


Mx1
myxovirus (influenza virus) resistance 1
1.3

4.5


Dnase1l3
deoxyribonuclease 1-like 3
1.3

23.9


Ifi204
interferon activated gene 204
1.2
2.9
9.0


Tnfrsf5
tumor necrosis factor receptor
1.2
2.8
3.9



superfamily, member 5


Wars
tryptophanyl-tRNA synthetase
1.2

3.5


Ly6c
lymphocyte antigen 6 complex, locus C
1.2

2.2


Psme1
proteasome (prosome, macropain) 28
1.2

2.8



subunit, alpha


4930422C14
hypothetical protein 4930422C14
1.2

8.2


D11Lgp2e
DNA segment, Chr 11, Lothar
1.2

16.8



Hennighausen 2, expressed


Samhd1
SAM domain and HD domain, 1
1.1

6.9


Dnase1l3
deoxyribonuclease 1-like 3
1.1

2.4


Gimap4
GTPase, IMAP family member 4
1.1

2.4


1110007F12Rik
RIKEN cDNA 1110007F12 gene
1.1

3.9


H2-Oa
histocompatibility 2, O region alpha locus
1.1

2.7


Pnp
purine-nucleoside phosphorylase
1.1

2.4


Rbl1
retinoblastoma-like 1 (p107)
1.1

4.1


C920025E04Rik
RIKEN cDNA C920025E04 gene
1.1

3.0


Cxcr3
chemokine (C—X—C motif) receptor 3
1.1

4.1


Klrk1
killer cell lectin-like receptor subfamily K,
1.1

3.9



member 1


Icsbp
interferon concensus sequence binding
1.0
2.0
8.1



protein


Klra7
killer cell lectin-like receptor, subfamily A,
1.0

2.7



member 7


BC010462
cDNA sequence BC010462
1.0

2.9


Pbef-pending
pre-B-cell colony-enhancing factor
1.0

2.1


Prkr
protein kinase, interferon-inducible
1.0

3.0



double stranded RNA dependent


Wars
tryptophanyl-tRNA synthetase
1.0

4.0


Asahl
N-acylsphingosine amidohydrolase (acid
1.0

2.5



ceramidase)-like


Tlr3
toll-like receptor 3
1.0

2.4


1810054D07Rik
RIKEN cDNA 1810054D07 gene
1.0

4.6


9530028C05
product: similar to
0.9

2.9



HISTOCOMPATIBILITY 2, CLASS II



ANTIGEN E BETA [Mus musculus], full



insert sequence.


Sell
selectin, lymphocyte
0.9

3.7


Eif4e3
eukaryotic translation initiation factor 4E
0.9

3.1



member 3


2310016F22Rik
RIKEN cDNA 2310016F22 gene
0.9

17.4


Irg1
immunoresponsive gene 1
0.9

34.6


Klrb1b
killer cell lectin-like receptor subfamily B
0.9

2.7



member 1B


Tcf7
transcription factor 7, T-cell specific
0.9

10.1


Slamf7
SLAM family member 7
0.8

4.2


Ifi203
interferon activated gene 203
0.8

4.4


Cd3z
CD3 antigen, zeta polypeptide
0.8

6.9


MGI: 1923551
FLN29 gene product
0.7

3.0


Trim34
tripartite motif protein 34
0.7

2.2


Upp
uridine phosphorylase
0.6

6.5


Ngfr
nerve growth factor receptor
0.5
9.9
2.3


Ifi203
interferon activated gene 203
0.3

23.6
















TABLE 7







Injury-induced RITs in rejection



















ISO

ISO
WT
WT
WT
WT
WT



Gene Symbol
Gene Title
D21
ISO D7
D5
D5
D7
D14
D21
D42
Genbank




















1110028E10Rik
RIKEN cDNA 1110028E10 gene
1.5
2.1
0.9
2.4
2.2
2.7
2.7
3.1
BB478892


1200016E24Rik
RIKEN cDNA 1200016E24 gene
0.9
2.6
0.9
2.8
1.9
2.0
2.8
2.5
BF719154


1200016E24Rik
RIKEN cDNA 1200016E24 gene
1.1
2.4
1.0
2.6
2.4
1.5
3.2
1.6
AU018141


2610042L04Rik
RIKEN cDNA 2610042L04 gene
1.2
1.5
2.2
4.9
3.0
6.7
3.8
4.2
BM195235


9030408N13Rik
RIKEN cDNA 9030408N13 gene
1.1
2.5
1.6
6.2
9.2
11.9
11.9
11.1
NM_025779


Abp1
amiloride binding protein 1 (amine oxidase,
0.8
3.1
0.9
4.0
2.6
10.0
8.0
5.0
BC021880



copper-containing)


Adamts1
a disintegrin-like and metalloprotease (reprolysin
1.1
2.9
1.5
4.2
2.2
5.4
4.0
4.7
D67076



type) with thrombospondin type 1 motif, 1


Adamts4
a disintegrin-like and metalloprotease (reprolysin
1.1
3.3
1.1
3.2
2.7
4.4
4.1
5.6
BB443585



type) with thrombospondin type 1 motif, 4


Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
0.5
4.0
1.3
4.1
2.7
2.6
3.7
4.5
NM_009022


Anln
anillin, actin binding protein (scraps homolog,
1.3
2.3
1.9
2.3
3.3
4.0
3.3
3.6
BI690018




Drosophila)


Arrb2
similar to Beta-arrestin 2 (Arrestin, beta 2)
0.9
2.1
1.0
5.2
8.6
11.4
10.8
9.8
BC016642


Asns
asparagine synthetase
0.6
2.2
1.1
3.0
1.5
3.6
3.2
5.0
AV212753


Basp1
brain abundant, membrane attached signal
1.0
2.2
1.4
4.9
6.0
14.2
13.6
18.3
AK011545



protein 1


Bcl3
B-cell leukemia/lymphoma 3
1.7
3.6
1.8
7.2
8.0
4.8
7.0
4.7
NM_033601


Bcl6
B-cell leukemia/lymphoma 6
3.9
2.3
2.3
2.1
2.5
2.3
2.4
2.1
BB183854


Birc1b
baculoviral IAP repeat-containing 1b
0.9
1.5
2.1
2.5
2.8
6.2
4.0
5.9
NM_010872


Bsf3-pending
B-cell stimulating factor 3
0.6
2.0
2.1
2.1
2.2
3.5
5.0
3.3
BB825816


C1qa
complement component 1, q subcomponent,
1.4
3.9
2.8
10.3
15.7
29.2
24.1
28.8
NM_007572



alpha polypeptide


C1qb
complement component 1, q subcomponent,
2.3
2.2
2.0
3.4
5.0
10.2
6.6
7.7
AW227993



beta polypeptide


C79673
expressed sequence C79673
1.4
2.7
1.4
19.9
24.5
41.2
33.5
38.1
BG066664


Car13
carbonic anhydrase 13
0.6
2.1
1.5
4.2
2.2
4.5
3.7
3.3
NM_024495


Casp12
caspase 12
1.1
1.5
2.3
3.0
2.5
9.1
6.6
7.0
NM_009808


Ccl2
chemokine (C—C motif) ligand 2
1.1
2.9
1.2
7.4
7.5
10.7
9.3
10.5
AF065933


Ccl9
chemokine (C—C motif) ligand 9
0.7
2.4
1.2
3.1
5.0
6.4
11.4
12.1
NM_011338


Ccl9
chemokine (C—C motif) ligand 9
1.0
5.8
1.1
8.6
12.1
18.2
23.3
33.2
AF128196


Ccnb1
cyclin B1
1.0
2.7
2.4
9.9
6.7
8.6
5.6
5.5
X58708


Ccr2
chemokine (C—C) receptor 2
1.0
6.9
3.9
23.1
30.9
39.4
22.4
9.4
U47035


Ccr2
chemokine (C—C) receptor 2
1.9
3.2
3.6
13.4
17.7
17.5
14.1
7.8
NM_009915


Cd14
CD14 antigen
0.9
3.6
1.3
7.3
2.8
5.4
4.2
4.6
NM_009841


Cd44
CD44 antigen
1.1
3.7
2.1
9.8
14.3
29.6
28.9
25.0
BC005676


Cdc2a
cell division cycle 2 homolog A (S. pombe)
0.3
3.4
1.3
5.1
5.0
5.3
3.6
3.7
NM_007659


Ch25h
cholesterol 25-hydroxylase
1.0
2.1
1.4
6.7
8.0
12.3
6.7
12.7
NM_009890


Clca2
chloride channel calcium activated 2
0.7
2.2
2.2
2.2
1.4
3.7
2.1
5.3
AF108501


Clca2
chloride channel calcium activated 2
1.1
2.8
2.6
2.1
1.3
1.1
1.8
2.0
AF108501


Clecsf10
C-type (calcium dependent, carbohydrate
1.0
3.6
1.5
4.8
7.0
8.1
8.8
13.4
NM_020001



recognition domain) lectin, superfamily member



10


Clecsf10
C-type (calcium dependent, carbohydrate
1.0
4.0
1.3
5.0
6.8
16.5
10.4
19.5
AF240358



recognition domain) lectin, superfamily member



10


Clecsf6
C-type (calcium dependent, carbohydrate
1.1
4.3
3.8
4.7
7.0
12.8
14.3
14.4
NM_011999



recognition domain) lectin, superfamily member 6


Clecsf6
C-type (calcium dependent, carbohydrate
1.4
3.4
1.8
3.5
6.0
16.3
14.1
13.4
BC006623



recognition domain) lectin, superfamily member 6


Clecsf8
C-type (calcium dependent, carbohydrate
1.1
2.4
1.6
2.1
2.9
2.9
3.1
7.4
NM_010819



recognition domain) lectin, superfamily member 8


Clecsf9
C-type (calcium dependent, carbohydrate
1.0
4.3
2.8
16.2
18.5
12.2
7.5
11.6
BC003218



recognition domain) lectin, superfamily member 9


Col1a1
procollagen, type I, alpha 1
0.4
2.0
1.3
5.0
8.4
4.8
9.1
3.4
BI794771


Col1a1
procollagen, type I, alpha 1
2.0
6.8
1.9
11.3
26.7
18.9
31.4
17.8
U08020


Col1a2
procollagen, type I, alpha 2
1.0
2.4
1.5
4.3
6.3
8.9
7.0
7.6
BF227507


Col1a2
procollagen, type I, alpha 2
1.1
3.7
2.6
6.3
9.4
14.7
12.0
8.9
AW545978


Col3a1
procollagen, type III, alpha 1
1.1
4.8
2.6
5.4
6.8
15.5
8.9
11.0
BG968894


Col3a1
procollagen, type III, alpha 1
1.2
3.8
2.4
4.8
6.7
16.3
9.3
9.6
AW550625


Cp
ceruloplasmin
0.5
2.6
1.6
2.8
1.2
2.9
2.6
1.6
BB531328


Cp
ceruloplasmin
0.7
2.8
1.2
4.0
1.7
3.0
3.8
2.4
BB009037


Cp
ceruloplasmin
0.9
3.1
1.5
3.5
2.9
3.5
5.2
2.2
NM_007752


Cp
ceruloplasmin
0.9
3.1
1.7
4.4
1.8
3.0
4.1
2.3
NM_007752


Cp
ceruloplasmin
1.0
2.9
1.7
3.8
1.6
3.1
3.6
2.1
NM_007752


Cpe
carboxypeptidase E
1.3
2.5
2.5
2.2
1.3
1.3
1.6
0.9
BC010197


Crap
cardiac responsive adriamycin protein
0.6
2.2
1.2
2.1
1.3
4.0
4.0
4.1
AK009959


Crap
cardiac responsive adriamycin protein
0.7
3.5
1.8
3.3
1.6
7.4
6.3
9.3
NM_013468


Crlf1
cytokine receptor-like factor 1
1.9
5.2
1.2
10.6
12.2
11.5
13.4
18.1
NM_018827


Cspg2
chondroitin sulfate proteoglycan 2
0.7
2.2
1.3
4.0
3.7
11.3
5.2
11.1
BI692925


Cx3cr1
chemokine (C—X3—C) receptor 1
1.3
2.0
1.8
2.5
3.0
4.7
7.2
4.1
BC012653


Cxcl13
chemokine (C—X—C motif) ligand 13
1.2
2.9
1.3
3.6
2.3
1.3
2.0
1.8
NM_018866


Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-
3.0
2.5
3.2
2.1
2.5
3.0
3.0
2.9
BB667072



linked


Ddx3y
DEAD (aspartate-glutamate-alanine-aspartate)
2.5
2.9
3.2
2.4
2.2
2.1
2.3
2.9
AJ007376



box polypeptide, Y chromosome


Ddx3y
DEAD (aspartate-glutamate-alanine-aspartate)
3.1
3.5
3.3
3.1
3.1
4.1
3.2
3.8
AA210261



box polypeptide, Y chromosome


Dpysl3
dihydropyrimidinase-like 3
1.5
2.2
2.0
3.6
1.9
4.7
4.1
3.0
AV161550


Egr2
early growth response 2
0.6
2.0
1.3
3.7
4.6
6.2
7.7
6.6
X06746


Eif2s3y
eukaryotic translation initiation factor 2, subunit
2.4
2.8
2.4
2.9
2.4
3.6
2.9
3.0
NM_012011



3, structural gene Y-linked


Emr1
EGF-like module containing, mucin-like, hormone
1.2
2.4
1.8
2.9
5.0
10.0
10.4
11.3
U66888



receptor-like sequence 1


Evi2
ecotropic viral integration site 2
1.1
2.2
2.3
5.8
7.7
12.8
9.4
8.9
NM_010161


F13a
coagulation factor XIII, alpha subunit
1.2
2.5
1.7
2.8
2.9
3.7
3.2
9.3
NM_028784


Fbn1
fibrillin 1
1.1
2.3
2.0
2.5
2.8
5.6
4.1
5.4
NM_007993


Fcgr1
Fc receptor, IgG, high affinity I
1.2
2.2
2.0
7.0
9.7
23.7
11.0
21.4
AF143181


Fcgr3
Fc receptor, IgG, low affinity III
1.2
3.0
2.1
5.2
8.3
25.9
17.6
30.6
NM_010188


Fga
fibrinogen, alpha polypeptide
1.0
3.9
0.8
7.3
2.7
1.1
0.6
0.7
BC005467


Fn1
fibronectin 1
1.1
2.3
1.6
2.1
3.1
7.6
7.6
7.8
BC004724


Fos
FBJ osteosarcoma oncogene
0.9
2.1
1.2
5.3
5.6
9.6
5.7
7.6
AV026617


G7e-pending
G7e protein
1.0
2.3
1.3
4.6
3.7
6.0
5.2
4.5
NM_033075


G7e-pending
G7e protein
1.1
2.5
1.4
4.9
3.8
6.2
6.3
3.8
BC027314


Gm1549
gene model 1549, (NCBI)
1.1
1.2
2.2
2.6
2.2
2.7
1.1
2.6
AJ319753


Gp49b
glycoprotein 49 B
1.4
5.2
2.6
10.1
13.9
28.0
17.8
32.0
U05264


Havcr1
hepatitis A virus cellular receptor 1
0.5
4.2
1.4
3.1
1.0
3.1
0.7
1.3
NM_134248


Hmmr
hyaluronan mediated motility receptor (RHAMM)
0.6
2.2
1.4
2.8
2.9
2.0
1.9
1.8
NM_013552


Igl-V1
immunoglobulin lambda chain, variable 1
3.7
4.6
2.1
3.3
3.3
36.1
40.9
32.9
AK008145


Igsf6
immunoglobulin superfamily, member 6
1.0
2.6
0.9
13.7
18.5
30.5
22.4
25.3
NM_030691


Il1b
interleukin 1 beta
1.2
3.7
1.1
2.1
2.2
5.1
3.5
5.2
BC011437


Il1rn
interleukin 1 receptor antagonist
0.9
3.1
1.7
4.7
3.9
11.8
5.5
12.5
M57525


Itgam
integrin alpha M (CD11b)
1.2
3.8
2.1
5.5
7.9
11.0
8.8
10.8
NM_008401


Kif20a
kinesin family member 20A
1.3
2.2
2.6
3.4
3.9
4.2
2.9
3.4
NM_009004


Kif22-ps
kinesin family member 22, pseudogene
0.9
2.8
2.2
5.8
5.3
5.7
3.8
4.0
BB251322


Krt20
keratin 20
1.1
2.4
1.5
2.9
1.5
8.7
7.8
11.8
AF473907


Lcn2
lipocalin 2
1.0
15.4
2.2
27.6
11.8
40.9
35.8
53.0
X14607


Lcp1
lymphocyte cytosolic protein 1
0.9
2.3
1.5
14.1
15.8
20.0
15.2
18.3
BC022943


Lgals1
lectin, galactose binding, soluble 1
0.7
2.0
1.3
2.6
2.5
4.1
2.8
4.1
AI642438


Lgals1
lectin, galactose binding, soluble 1
0.9
2.0
1.1
3.0
2.8
3.6
3.1
3.1
NM_008495


Lif
leukemia inhibitory factor
1.8
3.3
1.4
4.5
3.8
3.8
3.7
4.7
BB235045


Lox
lysyl oxidase
0.6
5.8
2.3
8.0
6.3
22.5
12.5
31.2
M65143


Lox
lysyl oxidase
0.8
2.5
1.3
4.1
3.1
9.8
6.8
12.9
NM_010728


Lrg1
leucine-rich alpha-2-glycoprotein
1.3
6.3
0.5
8.3
2.5
5.3
5.2
4.2
NM_029796


Lyzs
lysozyme
1.4
7.7
2.7
22.8
26.8
39.5
43.7
22.1
AV058500


Lyzs
lysozyme
1.5
4.9
1.8
13.6
19.0
25.2
21.3
25.9
AW208566


Lyzs
lysozyme
1.6
7.9
2.7
19.0
20.9
38.2
19.1
32.7
AV066625


Mad2l1
MAD2 (mitotic arrest deficient, homolog)-like 1
0.9
2.2
1.6
4.6
3.8
4.5
2.8
2.8
NM_019499



(yeast)


Mcmd
mini chromosome maintenance deficient (S. cerevisiae)
1.3
1.8
2.2
6.1
5.7
5.1
5.0
3.6
C80350


Mcmd6
mini chromosome maintenance deficient 6 (S. cerevisiae)
1.0
2.0
1.8
4.5
5.2
4.4
3.7
3.0
BB099487


Mki67
antigen identified by monoclonal antibody Ki 67
0.8
2.6
2.2
9.8
11.3
7.8
8.8
3.7
X82786


Ms4a6d
membrane-spanning 4-domains, subfamily A,
0.9
5.6
3.3
19.7
33.6
53.6
29.3
39.4
NM_026835



member 6D


Ms4a7
membrane-spanning 4-domains, subfamily A,
1.3
2.5
2.1
2.9
5.5
13.9
15.4
15.4
BC024402



member 7


Msn
moesin
1.2
2.0
1.3
2.9
2.6
3.4
2.4
2.9
NM_010833


Ncf2
neutrophil cytosolic factor 2
1.3
2.1
2.0
4.6
5.7
13.6
9.3
11.5
NM_010877


Osmr
oncostatin receptor
1.0
2.4
1.8
3.5
2.7
4.3
5.5
4.7
NM_011019


Pira6
paired-Ig-like receptor A6
1.2
2.4
2.2
6.9
9.6
16.9
9.2
8.4
NM_011093


Plac8
placenta-specific 8
0.8
2.0
1.3
7.5
7.1
6.5
5.9
5.0
AF263458


Plek
pleckstrin
0.9
2.6
2.3
8.3
11.9
18.2
12.5
15.4
AF181829


Postn
periostin, osteoblast specific factor
1.0
2.8
2.5
2.7
2.9
8.0
7.2
14.4
BI110565


Prc1
protein regulator of cytokinesis 1
0.7
2.4
3.1
5.4
4.3
6.0
3.7
3.6
BC005475


Ptgs2
prostaglandin-endoperoxide synthase 2
0.8
4.8
2.0
4.1
6.9
13.4
5.6
9.3
M88242


Rad51ap1
RAD51 associated protein 1
0.7
2.1
0.6
4.7
3.4
2.2
2.6
2.5
BC003738


Rarres2
retinoic acid receptor responder (tazarotene
2.2
2.4
1.3
3.6
2.7
7.4
5.9
6.5
AV012073



induced) 2


Rrm2
ribonucleotide reductase M2
0.9
2.3
1.4
5.1
3.4
3.9
2.4
3.2
NM_009104


Rrm2
ribonucleotide reductase M2
1.0
2.2
1.5
4.8
3.9
4.8
3.1
2.5
AV301324


Runx1
runt related transcription factor 1
0.9
2.3
1.3
3.8
3.2
7.5
7.8
8.8
BI696226


S100a8
S100 calcium binding protein A8 (calgranulin A)
0.5
8.6
0.6
4.8
2.4
2.5
3.6
3.6
NM_013650


Saa1
serum amyloid A 1
1.0
5.8
1.7
27.3
3.7
6.3
3.2
1.3
NM_009117


Saa2
serum amyloid A 2
0.8
3.6
1.0
8.9
1.6
3.9
1.6
1.3
NM_011314


Saa3
serum amyloid A 3
0.8
2.4
0.9
5.5
4.2
3.6
2.1
4.7
NM_011315


Serpine1
serine (or cysteine) proteinase inhibitor, clade E,
1.1
5.6
0.9
6.5
10.0
23.4
11.0
32.2
NM_008871



member 1


Slc25a24
solute carrier family 25 (mitochondrial carrier,
0.8
2.0
1.5
2.3
2.2
5.4
3.5
4.1
BF578055



phosphate carrier), member 24


Smcy
selected mouse cDNA on the Y
2.2
2.5
2.4
2.3
2.8
2.3
2.7
2.1
AF127244


Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
1.0
2.5
1.6
4.9
3.4
8.8
5.5
5.7
NM_133888


Socs3
suppressor of cytokine signaling 3
0.7
6.8
2.5
16.9
12.9
19.2
13.5
18.9
BB241535


Socs3
suppressor of cytokine signaling 3
1.4
6.2
1.2
12.4
11.4
9.4
11.6
12.9
BB831725


Sprr2f
small proline-rich protein 2F
0.8
5.8
1.4
2.4
1.1
46.4
26.1
22.6
NM_011472


Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
1.4
2.0
1.5
5.7
7.7
11.4
7.7
7.1
BG064688


Syncrip
synaptotagmin binding, cytoplasmic RNA
3.1
3.6
2.7
4.0
3.4
4.7
3.2
4.0
BG920261



interacting protein


Tapbpl
TAP binding protein-like
0.8
1.2
2.3
8.7
7.4
7.4
6.9
5.1
BC017613


Tgfbi
transforming growth factor, beta induced, 68 kDa
1.0
2.5
2.1
4.6
4.6
8.0
6.0
5.3
BB532080


Tiarp-pending
Tnfa-induced adipose-related protein
1.0
3.4
1.4
4.1
1.4
1.3
2.4
2.1
NM_054098


Timd2
T-cell immunoglobulin and mucin domain
1.8
2.7
2.4
2.5
1.6
1.6
0.5
1.0
BC025096



containing 2


Timd2
T-cell immunoglobulin and mucin domain
2.8
4.1
3.5
5.2
3.3
3.3
1.7
2.4
BC028829



containing 2


Timp1
tissue inhibitor of metalloproteinase 1
1.3
8.3
1.9
15.5
15.3
29.1
16.6
26.4
BC008107


Tnc
tenascin C
0.3
3.3
1.4
2.4
3.3
4.4
5.5
10.4
NM_011607


Tnfrsf12a
tumor necrosis factor receptor superfamily,
1.2
3.1
1.2
5.6
3.1
5.6
4.4
4.1
NM_013749



member 12a


Tnfrsf12a
tumor necrosis factor receptor superfamily,
1.2
2.3
1.2
4.9
2.7
4.8
4.3
2.9
NM_013749



member 12a


Tpte
transmembrane phosphatase with tensin
2.5
3.0
3.2
2.6
1.1
2.1
2.8
1.4
AJ311312



homology


Tubb6
tubulin, beta 6
0.8
5.8
1.0
13.5
12.0
13.0
11.2
21.8
NM_026473


Ugcg
UDP-glucose ceramide glucosyltransferase
2.1
2.0
1.3
2.4
3.0
6.0
3.9
4.5
NM_011673


Uty
ubiquitously transcribed tetratricopeptide repeat
2.2
2.7
2.5
2.2
1.5
1.6
1.2
1.7
NM_009484



gene, Y chromosome


Vcam1
vascular cell adhesion molecule 1
0.9
4.3
1.4
11.3
3.6
29.8
8.3
8.2
L08431


Vim
vimentin
0.9
2.0
1.5
5.6
8.1
12.5
7.2
9.5
AV147875


Ywhag
3-monooxgenase/tryptophan 5-monooxgenase
2.4
2.1
0.3
2.0
2.2
2.7
1.9
2.2
NM_018871



activation protein, gamma polypeptide
















TABLE 8







Functional annotation of injury-induced RIT













Gene

ISO D7 vs
ISO D5 vs
WT D5 vs
IFN-γ
Tgf-β1


Symbol
Gene Title Affymetrix
NCBA
NCBA
NCBA
regulated
regulated
















Timp1
tissue inhibitor of metalloproteinase 1
8.3
1.9
15.5
yes
yes


Socs3
suppressor of cytokine signaling 3
6.8
2.5
16.9

yes


yes



Col3a1
procollagen, type III, alpha 1
4.8
2.6
5.4

yes


yes



Il1b
interleukin 1 beta
3.7
1.1
2.1
yes


Cd14
CD14 antigen
3.6
1.3
7.3

yes


yes



Adamts4
a disintegrin-like and metalloprotease
3.3
1.1
3.2

yes



motif, 4


Fcgr3
Fc receptor, IgG, low affinity III
3.0
2.1
5.2
yes


Ccl2
chemokine (C—C motif) ligand 2
2.9
1.2
7.4
yes


Plek
pleckstrin
2.6
2.3
8.3
yes


Cp
ceruloplasmin
2.6
1.6
2.8
yes


Smpdl3b
sphingomyelin phosphodiesterase, acid-
2.5
1.6
4.9
yes



like 3B


Lox
lysyl oxidase
2.5
1.3
4.1

yes


yes



Tgfbi
transforming growth factor, beta induced,
2.5
2.1
4.6

yes


yes




68 kDa


Col1a2
procollagen, type I, alpha 2
2.4
1.5
4.3

yes


yes



Fbn1
fibrillin 1
2.3
2.0
2.5

yes


Fn1
fibronectin 1
2.3
1.6
2.1

yes


yes



Fcgr1
Fc receptor, IgG, high affinity I
2.2
2.0
7.0
yes


Cspg2
chondroitin sulfate proteoglycan 2
2.2
1.3
4.0

yes


yes




(Versican)


Arrb2
similar to Beta-arrestin 2 (Arrestin, beta 2)
2.1
1.0
5.2
yes


Fos
FBJ osteosarcoma oncogene
2.1
1.2
5.3
yes


Ncf2
neutrophil cytosolic factor 2
2.1
2.0
4.6
yes


Col1a1
procollagen, type I, alpha 1
2.0
1.3
5.0

yes


yes



Vim
vimentin
2.0
1.5
5.6

yes


yes



Casp12
caspase 12
1.5
2.3
3.0
yes


Postn
periostin, osteoblast specific factor
2.8
2.5
2.7

yes





Bold letters indicate similar effects of cytokines, whereas italics indicate opposite effects.






Example 2
RITs and GRITs Identified Using a Second Algorithm

A second, more refined algorithm was used to identify RITs and GRITs. This method involved RMA (robust multichip analysis).


Revised GRITs Algorithm


Statistical analysis: Raw microarray data was pre-processed using an RMA method (Bioconductor 1.7; R version 2.2). Microarrays for control and treatment groups were preprocessed separately for each mouse strain combination. After preprocessing, data sets were subjected to variance-based filtering, i.e., all probe sets that had an inter-quartile range of less than 0.5 (log2 units), across all chips, were removed. Filtered data were then used for transcript selection. To be selected, a transcript was required to have a corrected p-value of 0.01 or lower, and had to be increased at least two-fold vs. appropriate controls. Corrected p-values (q-values) were calculated using the “limma” package (fdr adjustment method), which was uses an empirical Bayes method for assigning significance. The mean normalized value for replicate samples was used for further analysis. Finally, the data were imported into the GeneSpring™ 7.2 (Agilent, Palo Alto, Calif.) for further analyses and creation of transcript lists.


Selection and removal of transcripts associated with cytotoxic T cells: The previously defined CTL associated transcripts (CAT) selection was refined, using the transcriptome of CD8+ cells isolated from allo.CBA D5 into B6 allografts, and the CTL cell line transcriptome. Microarray data were normalized (GCOS/GeneSpring) to normal B6 kidneys. Transcripts expressed in the CTL line and in CD8 cells isolated from day 5 allografts (P flags in both samples) were selected based on their ≧5-fold expression vs. normal NCBA kidney. This selection yielded 1849 probe sets. These CTL and CD8-associated transcripts (expanded CATs) were removed from all transcript lists prior to any analysis. An exception was made for Psmb8, Psmb9 and Cc15 transcripts. Although prominently expressed in CTL, they also were expressed in rIFNg treated kidneys and/or a macrophage cell line.


Selection and removal of transcripts related to strain differences, somatically rearranged genes, and NK receptors: All probe sets showing differences in the basal signal (either 5-fold increased or decreased) between normal CBA, B6 and BALB/c kidneys were selected by the RMA-based method. These probe sets then were removed from the final transcript lists to reduce the influence of strain differences. Transcripts expressed by somatically rearranged genes, i.e., immunoglobulin genes, also were removed. In addition, transcripts for NK receptors of the Klr family were removed.


Development of the unique transcript lists: The term “transcript” refers to an mRNA identified by one or more numbered Affymetrix probe sets, while a “unique transcript” refers to an mRNA identified by only one probe set; these show the highest fold change of expression in the allografts at day 5 post-transplant. Certain probe sets representing the same transcript could appear in more than one list. These were arbitrarily kept only in the first list in which they appeared (e.g., tGRITs), and were eliminated from other lists (e.g., oGRITs, see below). All transcript name abbreviations use Entrez Gene nomenclature, which is available on the World Wide Web at ncbi.nlm.nih.gov/entrez).


IFN-γ-Dependent Rejection Induced Transcripts (GRITs)


The algorithms for transcript selection (applied after removing CATs and strain-differing transcripts) are shown in FIGS. 8A, 8B, and 8C. Fifty-eight transcripts were identified that were rIFN-γ-dependent in normal kidneys of CBA, B6 and BALB/c mice.


Transcripts increased at least 2-fold in day 5 allografts were termed “rejection-induced.” The inflammatory changes at day 5 did not fulfill the histologic criteria for rejection (tubulitis), but the patterns established at day 5 were highly conserved as rejection lesions evolved. 1319 unique rejection-induced transcripts were identified in D5 kidney allografts of B6, CBA, and BALB/c strains (FIG. 8B).


Rejection-induced transcripts that were IFN-γ-dependent in rejection were identified by studying allografts in IFN-γ-deficient (GKO) hosts. Kidney allografts from wild-type BALB/c into B6 (allo.BALB/c) were compared to BALB/c.GKO donors (H-2d) transplanted into B6.GKO (H-2b) recipients (allo.GKO D5). 443 rejection-induced transcripts were identified that were at least 2-fold (signal ratio) greater when IFN-γ was present than when it was absent. Of these, 55 transcripts (47 of which were unique transcripts) also were increased by rIFN-γ (FIG. 8C, Table 9), and thus were labeled true interferon gamma dependent rejection-induced transcripts (tGRITs). The remaining transcripts, 270 of which were unique transcripts, were not 2-fold induced by rIFN-γ in normal kidneys, but nevertheless were IFN-γ dependent in rejecting kidneys (FIG. 8C). To reflect their lower inducibility by rIFN-7, these transcripts were termed “occult” GRITs (oGRITs; Table 10).


The “tGRIT” and “oGRIT” terms used in this example are equivalent to the “GRIT” term used in Example 1, i.e., the GRIT category includes tGRITs and oGRITs. On average, there was 70% overlap between the GRITs identified by the RMA method with the (GCOS/GeneSpring) method described in Example 1.


Injury and Repair Induced Transcripts (IRITs) Algorithm


Transcript selection: Samples preprocessing, normalization and data filtering was done using the RMA-based method. Data also were corrected for the tGRITs, oGRITs and new CTL associated transcripts before transcript selection. The following algorithm was used (FIG. 9): transcripts were required to be increased in at least one of the isografts day 1-day 21 (≧2-fold, p(fdr)=0.01, where “fdr” is the false discovery rate), and also in allo.CBA D5 (≧2-fold, p(fdr)=0.01). Transcripts satisfying these criteria were selected, and the overlapping 372 transcripts were termed injury and repair-induced transcripts (IRITs). The final list, corrected for polymorphisms, contained 303 unique (highest expression in allo.CBA D5 vs NCBA) IRITs (Table 11).


The IRITs listed in Table 11 show a substantial overlap with the RITs, the injury-induced RITs and the GRIT-like lists of transcripts established as described in Example 1. In addition, the IRITs recapitulate the Tgfb1 effect on the transcriptome of rejecting mouse kidneys, similarly to GRIT-like and injury-induced RITs.









TABLE 9







Refined true gamma interferon-dependent rejection-induced transcripts (tGRIT)














allo.CBA





NCBA
D5 vs


Gene symbol
Gene title
raw
NCBA
GenBank














—
—
144
25.0
BB734586


AI451557
expressed sequence AI451557
23
35.1
AV277444


AW112010
expressed sequence AW112010
144
46.8
BE688358


B2m
beta-2 microglobulin
3304
4.8
AI099111


Bst2
bone marrow stromal cell antigen 2
134
12.9
BC008532


C1r
complement component 1, r
86
13.3
NM_023143



subcomponent


C2
Complement component 2 (within H-2S),
315
4.4
AV227574



mRNA (cDNA clone MGC: 18582



IMAGE: 3992881)


Cxcl9
chemokine (C—X—C motif) ligand 9
81
129.5
NM_008599


D12Ertd647e
DNA segment, Chr 12, ERATO Doi 647,
652
4.8
AW554405



expressed


Gbp2
guanylate nucleotide binding protein 2
95
133.2
NM_010260


Gbp4
guanylate nucleotide binding protein 4
68
54.4
NM_018734


H2-Aa /// H2-
histocompatibility 2, class II antigen A,
926
10.2
AF119253


Ea
alpha /// histocompatibility 2, class II



antigen E alpha


H2-Ab1
histocompatibility 2, class II antigen A,
351
18.8
M15848



beta 1


H2-D1 /// H2-
histocompatibility 2, D region locus 1 ///
230
17.2
L23495


K1 /// H2-L ///
histocompatibility 2, K1, K region ///


LOC56628
histocompatibility 2, D region /// MHC



(A.CA/J(H-2K-f) class I antigen


H2-DMa
histocompatibility 2, class II, locus DMa
100
21.2
NM_010386


H2-DMb1
histocompatibility 2, class II, locus Mb1
58
19.2
NM_010387


H2-DMb1 ///
histocompatibility 2, class II, locus Mb1 ///
179
17.7
NM_010388


H2-DMb2
histocompatibility 2, class II, locus Mb2


H2-DMb2
histocompatibility 2, class II, locus Mb2
81
25.3
NM_010388


H2-Eb1
histocompatibility 2, class II antigen E beta
679
9.7
NM_010382


H2-K1
histocompatibility 2, K1, K region
373
15.8
S70184


H2-T10 /// H2-
histocompatibility 2, T region locus 10 ///
784
5.4
NM_010395


T22 /// H2-T9
histocompatibility 2, T region locus 22 ///



histocompatibility 2, T region locus 9


H2-T23
histocompatibility 2, T region locus 23
862
9.5
NM_010398


Herc5
hect domain and RLD 5
55
32.3
AW208668


Igtp
interferon gamma induced GTPase
342
34.4
NM_018738


Ii
Ia-associated invariant chain
1240
8.8
BC003476


Iigp1
interferon inducible GTPase 1
99
69.1
BM239828


Iigp2
interferon inducible GTPase 2
127
34.1
NM_019440


Il18bp
interleukin 18 binding protein
116
19.6
AF110803


Irgm
immunity-related GTPase family, M
485
14.5
NM_008326


Lgals3bp
lectin, galactoside-binding, soluble, 3
360
5.3
NM_011150



binding protein


LOC56628
MHC (A.CA/J(H-2K-f) class I antigen
63
3.8
M58156


Mpa2l
macrophage activation 2 like
50
174.1
BM241485


Mpeg1
macrophage expressed gene 1
217
18.8
L20315


Oasl2
2′-5′ oligoadenylate synthetase-like 2
56
22.8
BQ033138


Parp14
poly (ADP-ribose) polymerase family,
95
19.1
BC021340



member 14


Psmb10
proteasome (prosome, macropain)
251
16.2
NM_013640



subunit, beta type 10


Psmb8
proteosome (prosome, macropain)
205
29.6
NM_010724



subunit, beta type 8 (large multifunctional



peptidase 7)


Psmb9
proteosome (prosome, macropain)
142
25.3
NM_013585



subunit, beta type 9 (large multifunctional



peptidase 2)


Psme1
proteasome (prosome, macropain) 28
1008
4.5
NM_011189



subunit, alpha


Serpina10
serine (or cysteine) peptidase inhibitor,
95
44.9
BC018416



clade A (alpha-1 antiproteinase,



antitrypsin), member 10


Serping1
serine (or cysteine) peptidase inhibitor,
721
7.0
NM_009776



clade G, member 1


Stat1
signal transducer and activator of
350
23.9
AW214029



transcription 1


Tap1
transporter 1, ATP-binding cassette, sub-
60
24.0
AW048052



family B (MDR/TAP)


Tapbp
TAP binding protein
962
6.1
AF043943


Tgtp
T-cell specific GTPase
481
32.6
NM_011579


Ubd
ubiquitin D
47
255.8
NM_023137


Xdh
xanthine dehydrogenase
53
16.7
AV286265
















TABLE 10







Refined occult gamma interferon-dependent rejection-induced transcripts (oGRIT)













NCBA
allo.CBA D5



Gene Symbol
Gene Title
Raw
vs NCBA
Gen Bank














1-Mar
membrane-associated ring finger
21
7.4
BB134696



(C3HC4) 1


6-Sep
septin 6
81
4.0
BC010489


—
—
307
2.7
AV340322


—
—
261
3.4
AV340322


—
—
50
2.9
BG695418


—
—
51
15.6
BB668084


—
Transcribed locus
28
3.2
BB376947


—
Transcribed locus
52
60.2
AW111920


—
Transcribed locus
12
3.1
BG144448


—
—
15
2.9
BQ266693


—
Transcribed locus, weakly similar to
17
5.4
BB740904


—
NP_795929.1 hypothetical protein


—
LOC319587 [Mus musculus]


—
16 days neonate thymus cDNA, RIKEN
113
5.8
BI653857



full-length enriched library,



clone: A130050C20



product: hypothetical Butyrophylin-



like/SPla/RYanodine receptor



SPRY/B302, (SPRY)-like containing



protein, full insert sequence


—
—
15
4.9
BG072508


—
—
32
11.8
BB558917


0610025L06Rik
RIKEN cDNA 0610025L06 gene
183
3.9
AK012581


0610033I05Rik
RIKEN cDNA 0610033I05 gene
137
3.5
BC003333


1110007F12Rik
RIKEN cDNA 1110007F12 gene
422
3.7
BC020080


1110038F14Rik
RIKEN cDNA 1110038F14 gene
187
2.0
NM_054099


1500004A08Rik
RIKEN cDNA 1500004A08 gene
109
2.5
BB030508


1810009K13Rik
RIKEN cDNA 1810009K13 gene
136
2.1
AK007407


1810054D07Rik
RIKEN cDNA 1810054D07 gene
15
4.1
BB397062


2310016F22Rik ///
RIKEN cDNA 2310016F22 gene ///
39
11.0
BC020489


LOC223672
hypothetical protein LOC223672


2700019D07Rik
RIKEN cDNA 2700019D07 gene
160
2.7
BM937429


2810417H13Rik
RIKEN cDNA 2810417H13 gene
14
16.9
AK017673


4933430F08Rik
RIKEN cDNA 4933430F08 gene
128
6.4
AK016990


5133401N09Rik
RIKEN cDNA 5133401N09 gene
464
2.5
BC026742


5830443L24Rik
RIKEN cDNA 5830443L24 gene
49
115.5
NM_029509


5830458K16Rik
RIKEN cDNA 5830458K16 gene
149
13.3
BC024872


9130017N09Rik
RIKEN cDNA 9130017N09 gene
163
2.6
BQ030875


9330175E14Rik
RIKEN cDNA 9330175E14 gene
27
2.7
BB082472


9530028C05
hypothetical protein 9530028C05
80
5.0
BQ175154


9830147J24Rik
RIKEN cDNA 9830147J24 gene
46
56.7
BM241271


A430107D22Rik
RIKEN cDNA A430107D22 gene
60
3.4
AV312663


A630077B13Rik
RIKEN cDNA A630077B13 gene
17
92.0
BB239429


AB124611
cDNA sequence AB124611
33
10.5
BM246462


Adar
RNA adenosine deaminase 1 (Adar)
30
3.3
BB308291



mRNA, complete cds, alternatively



spliced


AI447904
expressed sequence AI447904
12
44.0
BM241008


AI447904 ///
expressed sequence AI447904 ///
32
29.7
BM241008


BC094916
cDNA sequence BC094916


AI451617
expressed sequence AI451617
19
11.2
BM241342


AI480535
expressed sequence AI480535
517
2.5
BQ176847


AI607873
expressed sequence AI607873
10
11.6
AI607873


AI661384
expressed sequence AI661384
11
5.3
BB034038


Aif1
allograft inflammatory factor 1
47
23.0
NM_019467


Ak7
adenylate kinase 7
231
3.0
AV256298


Akt3
thymoma viral proto-oncogene 3
74
3.5
BB521695


Arid5a
AT rich interactive domain 5A (Mrf1
74
3.0
BC027152



like)


Asahl
N-acylsphingosine amidohydrolase
140
6.8
BI106821



(acid ceramidase)-like


Atp8a1
ATPase, aminophospholipid transporter
67
6.0
AW610650



(APLT), class I, type 8A, member 1


AU020206
expressed sequence AU020206
69
12.1
BI151331


B230217C12Rik
RIKEN cDNA B230217C12 gene
30
3.3
BB376573


BC006779
cDNA sequence BC006779
95
4.9
BE853170


BC010462
cDNA sequence BC010462
84
4.1
BC010462


BC013672
cDNA sequence BC013672
12
3.8
BC013672


BC013712
cDNA sequence BC013712
97
9.6
BB262491


BC023105
cDNA sequence BC023105
20
42.8
BC023105


BC027057
cDNA sequence BC027057
24
3.9
BB040051


Btla
B and T lymphocyte associated
29
8.8
BM240873


C1s
complement component 1, s
156
13.0
BC022123



subcomponent


C2ta
class II transactivator
29
9.5
AF042158


C2ta
class II transactivator
40
6.7
AF042158


C4
complement component 4 (within H-2S)
367
6.9
NM_009780


Card4
caspase recruitment domain 4
132
3.0
BB138330


Casp1
caspase 1
44
9.6
BC008152


Casp11
caspase 11, apoptosis-related cysteine
39
13.6
NM_007609



peptidase


Casp12
caspase 12
33
9.5
NM_009808


Casp7
caspase 7
140
4.0
NM_007611


Ccl19
chemokine (C—C motif) ligand 19
305
2.1
NM_011888


Ccl5
chemokine (C—C motif) ligand 5
75
36.7
NM_013653


Ccl8
chemokine (C—C motif) ligand 8
36
22.0
NM_021443


Ccr5
chemokine (C—C motif) receptor 5
24
11.5
X94151


Ccr9
chemokine (C—C motif) receptor 9
16
2.4
AJ131357


Ccrl2
chemokine (C—C motif) receptor-like 2
73
2.7
AJ318863


Cd2
CD2 antigen
26
8.4
NM_013486


Cd274
CD274 antigen
50
27.3
NM_021893


Cd28
CD28 antigen
13
21.6
NM_007642


Cd40
CD40 antigen
70
7.1
BB220422


Cd48
CD48 antigen
29
25.5
BE634960


Cd5
CD5 antigen
21
10.0
NM_007650


Cd6
CD6 antigen
57
3.0
U12434


Cd69
CD69 antigen
12
6.4
AK017979


Cd72
CD72 antigen
40
5.7
BC003824


Cd86
CD86 antigen
27
8.8
NM_019388


Cerkl
ceramide kinase-like
34
13.8
BB205589


Clec2d
C-type lectin domain family 2, member d
211
3.1
NM_053109


Csprs
component of Sp100-rs
84
2.8
BB148221


Ctsc
cathepsin C
13
9.7
BM237633


Ctsw
cathepsin W
49
11.9
NM_009985


Cxcl10
chemokine (C—X—C motif) ligand 10
69
95.2
NM_021274


Cxcl11
chemokine (C—X—C motif) ligand 11
37
169.3
NM_019494


Cxcl16
chemokine (C—X—C motif) ligand 16
652
3.3
BC019961


Cxcl16 ///
chemokine (C—X—C motif) ligand 16 ///
99
2.9
AI662455


LOC574428
zinc finger, MYND domain containing



15


Cxcr3
chemokine (C—X—C motif) receptor 3
60
8.2
NM_009910


Cxcr6
chemokine (C—X—C motif) receptor 6
28
15.4
AF301018


Cybb
cytochrome b-245, beta polypeptide
52
21.8
NM_007807


Cyp4v3
cytochrome P450, family 4, subfamily
49
3.5
NM_133969



v, polypeptide 3


D11Ertd759e
DNA segment, Chr 11, ERATO Doi
363
5.0
AW556558



759, expressed


D11Lgp2e
DNA segment, Chr 11, Lothar
42
6.8
AF316999



Hennighausen 2, expressed


D14Ertd668e
DNA segment, Chr 14, ERATO Doi
115
6.5
AV280841



668, expressed


Dck
deoxycytidine kinase
13
7.8
NM_007832


Dnase1l3
deoxyribonuclease 1-like 3
28
6.3
BC012671


Dtx3l
deltex 3-like (Drosophila)
136
12.0
AV327407


Eif2ak2
eukaryotic translation initiation factor 2-
81
3.2
BE911144



alpha kinase 2


Eif4e3
eukaryotic translation initiation factor
162
5.2
BC027014



4E member 3


Enc1
ectodermal-neural cortex 1
77
4.4
BM120053


Epsti1
epithelial stromal interaction 1 (breast)
37
20.0
BF020640


Evl
Ena-vasodilator stimulated
45
8.3
AW553781



phosphoprotein


Fabp7
fatty acid binding protein 7, brain
259
6.6
NM_021272


Fas
Fas (TNF receptor superfamily
85
3.2
NM_007987



member)


Fbxo39
F-box protein 39
168
11.3
BB645745


Fbxo6b
F-box only protein 6b
301
2.8
NM_015797


Fbxw17
F-box and WD-40 domain protein 17
181
3.3
AV016303


Fcgr1
Fc receptor, IgG, high affinity I
35
20.5
AF143181


Fcgr1
Fc receptor, IgG, high affinity I
80
2.6
BB075261


Fcgr3a
Fc fragment of IgG, low affinity IIIa,
47
22.5
BC027310



receptor


Fgd2
FYVE, RhoGEF and PH domain
66
2.2
NM_013710



containing 2


Fgf13
fibroblast growth factor 13
18
2.0
AF020737


Fgl2
fibrinogen-like protein 2
31
45.9
BF136544


Fyb
FYN binding protein (Fyb), mRNA
31
4.2
BE853428


G1p2
interferon, alpha-inducible protein
40
17.2
AK019325


Gbp1
guanylate nucleotide binding protein 1
22
23.9
NM_010259


Gdap10
ganglioside-induced differentiation-
99
4.8
NM_010268



associated-protein 10


Gimap3
GTPase, IMAP family member 3
91
6.2
NM_031247


Gimap4
GTPase, IMAP family member 4
677
3.6
BC005577


Gimap7
GTPase, IMAP family member 7
28
12.3
BC026200


Gja4
gap junction membrane channel protein
86
2.0
AF216832



alpha 4


Gm376
PREDICTED: similar to putative
9
3.7
BB241847



purinergic receptor FKSG79 [Mus




musculus], mRNA sequence


Gpr18
G protein-coupled receptor 18
32
10.8
BG145550


Gsdmdc1
gasdermin domain containing 1
119
4.1
AK007710


Gvin1
GTPase, very large interferon inducible 1
98
43.2
BM243571


Gzmk
granzyme K
23
6.2
AB032200


H28
histocompatibility 28
106
10.0
BC024930


H2-D1
histocompatibility 2, D region locus 1
43
10.0
M33151


H2-M3
histocompatibility 2, M region locus 3
106
6.5
NM_013819


H2-Oa
histocompatibility 2, O region alpha
43
4.6
NM_008206



locus


H2-Q5
histocompatibility 2, Q region locus 5
40
5.5
NM_010393


H2-Q8
histocompatibility 2, Q region locus 8
23
2.2
AK013097


H2-T24
histocompatibility 2, T region locus 24
46
3.6
L22338


Hck
hemopoietic cell kinase
41
18.7
NM_010407


Hk3
hexokinase 3
84
2.9
BB324660


Hpse
Heparanase (Hpse), mRNA
42
5.6
BG094050


Hrasls3
HRAS like suppressor 3
166
20.1
BB404920


Ibrdc3
IBR domain containing 3
133
8.4
AK015966


Icos
inducible T-cell co-stimulator
21
5.4
AB023132


Ifi202b
interferon activated gene 202B
27
64.8
AV229143


Ifi203 /// Ifi204 ///
interferon activated gene 203 ///
11
82.9
AI481797


Ifi205 /// Mnda ///
interferon activated gene 204 ///


LOC545386
interferon activated gene 205 ///



myeloid cell nuclear differentiation



antigen /// similar to Interferon-



activatable protein 205 (IFI-205) (D3



protein)


Ifi203 ///
interferon activated gene 203 /// similar
64
10.1
BC008167


LOC547362
to interferon-inducible protein 203


Ifi204 /// Mnda
interferon activated gene 204 ///
13
13.7
NM_008329



myeloid cell nuclear differentiation



antigen


Ifi205 /// Mnda
interferon activated gene 205 ///
29
92.9
AI481797



myeloid cell nuclear differentiation



antigen


Ifi27
interferon, alpha-inducible protein 27
119
7.4
AY090098


Ifi35
interferon-induced protein 35
406
6.6
AW986054


Ifi44
interferon-induced protein 44
121
8.0
BB329808


Ifi47
interferon gamma inducible protein 47
196
40.5
NM_008330


Ifih1
interferon induced with helicase C
181
5.5
AY075132



domain 1


Ifit1
interferon-induced protein with
29
23.3
NM_008331



tetratricopeptide repeats 1


Ifit2
interferon-induced protein with
125
32.5
NM_008332



tetratricopeptide repeats 2


Ifit3
interferon-induced protein with
317
6.6
NM_010501



tetratricopeptide repeats 3


IFNg
interferon gamma
25
22.9
K00083


Il10ra
interleukin 10 receptor, alpha
29
4.8
NM_008348


Il12rb1
interleukin 12 receptor, beta 1
32
2.4
NM_008353


Il16
interleukin 16
88
2.6
BC026894


Il18
interleukin 18
141
2.6
NM_008360


Il2rb
interleukin 2 receptor, beta chain
55
4.7
M28052


Il2rb
interleukin 2 receptor, beta chain
27
8.6
M28052


Il2rg
interleukin 2 receptor, gamma chain
121
18.6
L20048


Indo
indoleamine-pyrrole 2,3 dioxygenase
21
2.6
NM_008324


Inpp1
inositol polyphosphate-1-phosphatase
63
3.0
NM_008384


Irf1
interferon regulatory factor 1
312
14.9
NM_008390


Irf7
interferon regulatory factor 7
118
6.4
NM_016850


Irf8
interferon regulatory factor 8
157
12.0
BG069095


Irg1
immunoresponsive gene 1
31
17.9
L38281


Isg20
interferon-stimulated protein
51
5.4
BC022751


Itgal
integrin alpha L
41
2.9
AF065902


Itgal
integrin alpha L
41
20.3
BI554446


Lair1
leukocyte-associated Ig-like receptor 1
29
7.8
AK017222


Lck
lymphocyte protein tyrosine kinase
40
25.5
BC011474


LOC432460
similar to RIKEN cDNA 6330442E10
23
2.7
BB302103



gene


LOC544986 ///
similar to hypothetical protein
47
7.3
BM195235


LOC544991 ///
LOC67055 /// similar to hypothetical


LOC544997 ///
protein LOC67055 /// similar to


B930046C15Rik
hypothetical protein LOC67055 ///


/// LOC545001 ///
RIKEN cDNA B930046C15 gene ///


LOC545005 ///
hypothetical protein LOC545001 ///


LOC545007 ///
hypothetical protein LOC545005 ///


LOC545008 ///
hypothetical protein LOC545007 ///


2610042L04Rik ///
similar to hypothetical protein


LOC545017
LOC67055 /// RIKEN cDNA



2610042L04 gene /// similar to



hypothetical protein LOC67055


LOC547214
similar to G protein coupled receptor
14
3.8
AF140709


Lst1
leukocyte specific transcript 1
125
8.9
U72644


Ly6c
lymphocyte antigen 6 complex, locus C
1041
3.9
NM_010741


Ly6i
lymphocyte antigen 6 complex, locus I
125
11.2
AF232024


Ly75
lymphocyte antigen 75
12
3.7
NM_013825


MGI: 1933403
type 1 tumor necrosis factor receptor
154
4.7
NM_030711



shedding aminopeptidase regulator


Mlkl
mixed lineage kinase domain-like
37
14.3
AK018636


Ms4a4b
membrane-spanning 4-domains,
18
92.0
BB199001



subfamily A, member 4B


Ms4a4c
membrane-spanning 4-domains,
11
48.3
NM_022429



subfamily A, member 4C


Ms4a4d
membrane-spanning 4-domains,
31
15.2
NM_025658



subfamily A, member 4D


Ms4a6b
membrane-spanning 4-domains,
30
70.6
NM_027209



subfamily A, member 6B


Ms4a6c
membrane-spanning 4-domains,
106
14.0
AF237910



subfamily A, member 6C


Mx1
myxovirus (influenza virus) resistance 1
22
3.8
M21039


Myb
myeloblastosis oncogene
10
2.9
BC011513


Nkg7
natural killer cell group 7 sequence
57
23.5
NM_024253


Nmi
N-myc (and STAT) interactor
267
7.2
BC002019


Oas1a
2′-5′ oligoadenylate synthetase 1A
119
8.7
BC018470


Oasl1
2′-5′ oligoadenylate synthetase-like 1
48
8.4
AB067533


P2ry13
purinergic receptor P2Y, G-protein
35
3.4
AK008013



coupled 13


P2ry14
purinergic receptor P2Y, G-protein
57
3.1
AF177211



coupled, 14


Parp11
poly (ADP-ribose) polymerase family,
155
2.7
BB026163



member 11


Parp12
poly (ADP-ribose) polymerase family,
161
8.6
BM227980



member 12


Parp3
poly (ADP-ribose) polymerase family,
141
4.4
BC014870



member 3


Parp9
poly (ADP-ribose) polymerase family,
179
12.0
NM_030253



member 9


Parvg
parvin, gamma
41
2.5
NM_022321


Pbef1
pre-B-cell colony-enhancing factor 1
823
3.1
AW989410


Pigr
polymeric immunoglobulin receptor
857
3.7
NM_011082


Plac8
placenta-specific 8
208
21.7
AF263458


Pml
promyelocytic leukemia
58
2.7
BB667149


Pnp
purine-nucleoside phosphorylase
2805
2.1
BC003788


Pnp ///
purine-nucleoside phosphorylase ///
1262
2.7
AK008143


LOC545044
similar to purine-nucleoside



phosphorylase


Ppa1
pyrophosphatase (inorganic) 1
609
3.6
NM_026438


Ppfia4
protein tyrosine phosphatase, receptor
35
2.8
AK003571



type, f polypeptide (PTPRF), interacting



protein (liprin), alpha 4


Prkcq
protein kinase C, theta
118
3.0
AB062122


Procr
protein C receptor, endothelial
101
4.5
NM_011171


Psme2
proteasome (prosome, macropain) 28
709
6.2
NM_011190



subunit, beta


Ptprcap
protein tyrosine phosphatase, receptor
141
3.7
NM_016933



type, C polypeptide-associated protein


Rasa4
RAS p21 protein activator 4
32
2.3
NM_133914


Rbl1
retinoblastoma-like 1 (p107)
82
8.2
U27177


Rgs1
regulator of G-protein signaling 1
45
8.0
NM_015811


Rnase6
ribonuclease, RNase A family, 6
31
4.8
AW825994


Rsad2
radical S-adenosyl methionine domain
433
3.0
BB132493



containing 2


Samhd1
SAM domain and HD domain, 1
119
18.7
NM_018851


Scap1
src family associated phosphoprotein 1
39
2.9
BG075562


Sectm1
secreted and transmembrane 1
1125
4.0
AI481997


Serpina3g
serine (or cysteine) peptidase inhibitor,
44
98.9
BC002065



clade A, member 3G


Serpinb9
serine (or cysteine) peptidase inhibitor,
390
6.5
NM_009256



clade B, member 9


Sh2d1a
SH2 domain protein 1A
12
3.5
NM_011364


Slamf6
SLAM family member 6
19
12.8
AF248636


Slamf7
SLAM family member 7
23
4.2
AK016183


Slamf8
SLAM family member 8
18
45.2
BC024587


Slc28a2 ///
solute carrier family 28 (sodium-
14
8.5
NM_021520


LOC381417
coupled nucleoside transporter),



member 2 /// similar to solute carrier



family 28 (sodium-coupled nucleoside



transporter), member 2


Slc2a6
solute carrier family 2 (facilitated
33
3.0
BB196807



glucose transporter), member 6


Slfn1
schlafen 1
24
17.5
NM_011407


Slfn8
schlafen 8
55
4.3
BC024709


Snx10
sorting nexin 10
103
17.3
AK010399


Socs1
suppressor of cytokine signaling 1
45
5.3
AB000710


Sp100
nuclear antigen Sp100
81
2.7
U83636


Stat2
signal transducer and activator of
50
5.0
AF088862



transcription 2


Tap2
transporter 2, ATP-binding cassette,
171
11.3
BE691515



sub-family B (MDR/TAP)


Tapbpl
TAP binding protein-like
21
3.6
BC017613


Tapbpl
TAP binding protein-like
131
5.7
BC017613


Tbc1d10c
TBC1 domain family, member 10c
58
6.8
AV060417


Tbx21
T-box 21
18
5.5
NM_019507


Tcf7
transcription factor 7, T-cell specific
32
9.3
AI323642


Tinagl
tubulointerstitial nephritis antigen-like
500
2.4
BC005738


Tlr3
toll-like receptor 3
43
2.6
NM_126166


Tmprss4
transmembrane protease, serine 4
65
3.2
BC021368


Tnfrsf14
tumor necrosis factor receptor
43
3.2
BC022125



superfamily, member 14 (herpesvirus



entry mediator)


Tnfrsf7
tumor necrosis factor receptor
23
5.5
L24495



superfamily, member 7


Tnfsf10
tumor necrosis factor (ligand)
118
5.9
NM_009425



superfamily, member 10


Tor3a
torsin family 3, member A
63
4.8
AK009693


Tox
thymocyte selection-associated HMG
22
5.3
BB547854



box gene


Tpst1
protein-tyrosine sulfotransferase 1
132
2.9
NM_013837


Trafd1
TRAF type zinc finger domain
237
4.3
AK003586



containing 1


Treml4
triggering receptor expressed on
13
6.2
BB740529



myeloid cells-like 4


Trex1
three prime repair exonuclease 1
157
3.8
NM_011637


Trim21
tripartite motif protein 21
125
5.1
BC010580


Trim30
tripartite motif protein 30
48
11.5
AF220015


Trim34 ///
tripartite motif protein 34 /// similar to
29
9.7
AF220142


LOC434218
tripartite motif protein TRIM34 alpha


Tuba8
tubulin, alpha 8
37
3.0
NM_017379


Tyki
thymidylate kinase family LPS-inducible
131
3.1
AK004595



member


Ube1l
ubiquitin-activating enzyme E1-like
61
6.2
AK004894


Ube2l6
ubiquitin-conjugating enzyme E2L 6
50
7.8
BC008238


Unc93b1
unc-93 homolog B1 (C. elegans)
368
1.9
BC018388


Upp1
uridine phosphorylase 1
135
10.3
NM_009477


Usp18
ubiquitin specific peptidase 18
50
29.5
NM_011909


Vcam1
vascular cell adhesion molecule 1
112
45.1
BB250384


Wars
tryptophanyl-tRNA synthetase
322
3.3
AI528863


Zap70
zeta-chain (TCR) associated protein
43
6.4
NM_009539



kinase


Zbp1
Z-DNA binding protein 1
75
23.3
AK008179


Zc3h12d
zinc finger CCCH-type containing 12D
19
6.7
BB508669


Zfpn1a3
zinc finger protein, subfamily 1A, 3
16
14.6
BB151746



(Aiolos)
















TABLE 11







Refined injury and repair-induced transcripts (IRIT)












allo.CBA D5



Gene Symbol
Gene Title
vs NCBA
Genbank













—
Transcribed locus
2.8
AA266723


1110006O17Rik
RIKEN cDNA 1110006O17 gene
4.6
BB736636


1200008O12Rik
RIKEN cDNA 1200008O12 gene
12.5
AK004655


1200016E24Rik
RIKEN cDNA 1200016E24 gene
4.5
BF719154


1300002K09Rik
RIKEN cDNA 1300002K09 gene
4.7
AV222559


2200002D01Rik
RIKEN cDNA 2200002D01 gene
2.2
AK008617


2310014H01Rik
RIKEN cDNA 2310014H01 gene
5.2
AK009340


2410006H16Rik
RIKEN cDNA 2410006H16 gene
2.3
AA939619


2410129E14Rik
RIKEN cDNA 2410129E14 gene
3.9
AA986082


2610510J17Rik
RIKEN cDNA 2610510J17 gene
2.3
BM230253


2810052M02Rik
RIKEN cDNA 2810052M02 gene
3.8
NM_023320


2810406C15Rik
RIKEN cDNA 2810406C15 gene
4.8
BC025460


4833427B12Rik
RIKEN cDNA 4833427B12 gene
3.1
AW488914


4930579G24Rik
RIKEN cDNA 4930579G24 gene
2.8
BB821996


9030408N13Rik
RIKEN cDNA 9030408N13 gene
10.9
NM_025779


9030623C06Rik
RIKEN cDNA 9030623C06 gene
3.6
AF473907


9230117N10Rik
RIKEN cDNA 9230117N10 gene
13.0
NM_133775


Abca1
ATP-binding cassette, sub-family A (ABC1),
2.3
BB144704



member 1


Abp1
amiloride binding protein 1 (amine oxidase,
6.3
BC021880



copper-containing)


Acta2
actin, alpha 2, smooth muscle, aorta
2.0
NM_007392


Actn1
actinin, alpha 1
3.9
BE853286


Adam12
a disintegrin and metallopeptidase domain
2.0
NM_007400



12 (meltrin alpha)


Adam8
a disintegrin and metallopeptidase domain 8
4.2
NM_007403


Adamts1
a disintegrin-like and metallopeptidse
6.0
D67076



(reprolysin type) with thrombospondin type



1 motif, 1


Adamts4
a disintegrin-like and metallopeptidase
2.2
BB443585



(reprolysin type) with thrombospondin type



1 motif, 4


Adfp
adipose differentiation related protein
3.6
NM_007408


Adn
adipsin
3.5
NM_013459


Aldh1a2
aldehyde dehydrogenase family 1,
11.2
NM_009022



subfamily A2


Alox5ap
arachidonate 5-lipoxygenase activating
16.8
BC026209



protein


Anln
anillin, actin binding protein (scraps
4.6
BI690018



homolog, Drosophila)


Anxa1
annexin A1
3.2
NM_010730


Anxa2
annexin A2
3.4
NM_007585


Anxa3
annexin A3
4.0
AW702161


Apobec1
apolipoprotein B editing complex 1
3.5
BC003792


Arg2
arginase type II
7.9
NM_009705


Arhgap11a
Rho GTPase activating protein 11A
3.1
AV349116


Arpc1b
actin related protein 2/3 complex, subunit
7.8
BE979985



1B


Asf1b
ASF1 anti-silencing function 1 homolog B
4.4
BC003428



(S. cerevisiae)


Asns
asparagine synthetase
6.1
AV212753


Atad2
ATPase family, AAA domain containing 2
6.0
BM206009


Aurka
aurora kinase A
4.5
U80932


Aurkb
aurora kinase B
4.6
BC003261


AW492955
expressed sequence AW492955
3.3
AW492955


Bak1
BCL2-antagonist/killer 1
3.4
NM_007523


Basp1
brain abundant, membrane attached signal
8.6
AK011545



protein 1


Bcl3
B-cell leukemia/lymphoma 3
3.8
NM_033601


Bgn
biglycan
2.6
BC019502


Birc3
baculoviral IAP repeat-containing 3
6.6
NM_007464


Brrn1
barren homolog (Drosophila)
4.4
BB725358


Bub1
budding uninhibited by benzimidazoles 1
7.4
AF002823



homolog (S. cerevisiae)


C1qa
complement component 1, q
12.6
NM_007572



subcomponent, alpha polypeptide


C1qb
complement component 1, q
40.7
BB111335



subcomponent, beta polypeptide


C1qg
complement component 1, q
15.2
NM_007574



subcomponent, gamma polypeptide


C3
complement component 3
40.6
K02782


C330027C09Rik
RIKEN cDNA C330027C09 gene
4.3
AU018569


C3ar1
complement component 3a receptor 1
5.9
NM_009779


C79407
expressed sequence C79407
3.5
BE951628


Capg
capping protein (actin filament), gelsolin-like
7.4
NM_007599


Ccl12
chemokine (C—C motif) ligand 12
14.5
U50712


Ccl2
chemokine (C—C motif) ligand 2
11.0
AF065933


Ccl6
chemokine (C—C motif) ligand 6
10.6
BC002073


Ccl9
chemokine (C—C motif) ligand 9
9.3
AF128196


Ccna2
cyclin A2
7.3
X75483


Ccnb1
cyclin B1
6.4
AU015121


Ccnb1-rs1 ///
cyclin B1, related sequence 1 /// cyclin B1
5.3
NM_007629


Ccnb1


Ccnb2
cyclin B2
7.8
AK013312


Ccnf
cyclin F
2.4
NM_007634


Ccr1
chemokine (C—C motif) receptor 1
9.8
AV231648


Ccr2
chemokine (C—C motif) receptor 2
21.3
BB148128


Ccr2
chemokine (C—C motif) receptor 2
18.1
BB148128


Cd14
CD14 antigen
20.8
NM_009841


Cd52
CD52 antigen
31.9
NM_013706


Cd68
CD68 antigen
11.9
BC021637


Cdc20
cell division cycle 20 homolog (S. cerevisiae)
5.8
BB041150


Cdca1
cell division cycle associated 1
5.7
AK010351


Cdca3
cell division cycle associated 3
3.7
BI081061


Cdca5
cell division cycle associated 5
3.2
NM_026410


Cdca8
cell division cycle associated 8
3.7
AV307110


Cdh11
cadherin 11
3.8
NM_009866


Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
3.9
AK007630


Cebpb
CCAAT/enhancer binding protein (C/EBP),
3.8
NM_009883



beta


Cebpd
CCAAT/enhancer binding protein (C/EBP),
8.0
BB831146



delta


Cenpf
centromere autoantigen F
3.3
BE848253


Cfh
complement component factor h
2.3
AI987976


Cfi
complement component factor i
3.0
NM_007686


Chrnb1
cholinergic receptor, nicotinic, beta
2.3
M14537



polypeptide 1 (muscle)


Ckap2
cytoskeleton associated protein 2
2.9
BM208103


Ckap4
cytoskeleton-associated protein 4
2.1
BB818012


Cklfsf3
chemokine-like factor super family 3
3.4
NM_024217


Clca1 /// Clca2
chloride channel calcium activated 1 ///
3.7
AF108501



chloride channel calcium activated 2


Clec4a2
C-type lectin domain family 4, member a2
3.0
NM_011999


Clec4a2 ///
C-type lectin domain family 4, member a2 ///
2.7
BC006623


Clec4b
C-type lectin domain family 4, member b


Clec4a3
C-type lectin domain family 4, member a3
23.8
AK014135


Clec4n
C-type lectin domain family 4, member n
6.6
NM_020001


Clec7a
C-type lectin domain family 7, member a
13.0
NM_020008


Clu
clusterin
3.6
AV152288


Cnn2
calponin 2
3.9
BI663014


Col15a1
procollagen, type XV
2.1
AF011450


Col1a1
procollagen, type I, alpha 1
8.5
BI794771


Col1a2
procollagen, type I, alpha 2
9.6
BF227507


Col1a2
procollagen, type I, alpha 2
5.4
BF227507


Col3a1
procollagen, type III, alpha 1
13.4
AW550625


Col5a1
procollagen, type V, alpha 1
3.6
AW744319


Col5a2
procollagen, type V, alpha 2
7.2
AV229424


Col6a1
procollagen, type VI, alpha 1
2.1
NM_009933


Col6a2
procollagen, type VI, alpha 2
2.4
BI455189


Col6a3
procollagen, type VI, alpha 3
2.7
AF064749


Col8a1
procollagen, type VIII, alpha 1
3.1
AV292255


Colec12
collectin sub-family member 12
2.4
NM_130449


Cp
ceruloplasmin
6.8
BB332449


Cp
ceruloplasmin
6.0
BB009037


Crlf1
cytokine receptor-like factor 1
3.9
NM_018827


Cry1
cryptochrome 1 (photolyase-like)
2.3
BG069864


Csrp1
cysteine and glycine-rich protein 1
2.4
BF124540


Cstb
cystatin B
3.8
NM_007793


Ctsc
cathepsin C
10.5
NM_009982


Ctss
cathepsin S
19.4
NM_021281


Cx3cl1
chemokine (C—X3—C motif) ligand 1
2.3
AF010586


Cxcl1
chemokine (C—X—C motif) ligand 1
10.9
NM_008176


Cxcl14
chemokine (C—X—C motif) ligand 14
10.6
AF252873


Cybb
cytochrome b-245, beta polypeptide
21.0
AV373944


D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
9.6
NM_033075


Dcamkl1
Double cortin and calcium/calmodulin-
9.2
BB757120



dependent protein kinase-like 1, mRNA



(cDNA clone IMAGE: 5006471)


Dck
deoxycytidine kinase
11.8
BB030204


Dpt
dermatopontin
3.2
NM_019759


Dpysl3
dihydropyrimidinase-like 3
2.5
AV162270


Ect2
ect2 oncogene
3.3
NM_007900


Efemp2
epidermal growth factor-containing fibulin-
2.0
NM_021474



like extracellular matrix protein 2


Efhd2
EF hand domain containing 2
5.6
AK007560


Emilin1
elastin microfibril interfacer 1
2.1
NM_133918


Emr1
EGE-like module containing, mucin-like,
4.9
U66888



hormone receptor-like sequence 1


Entpd1
ectonucleoside triphosphate
4.0
BI151440



diphosphohydrolase 1


Ercc6l
excision repair cross-complementing rodent
2.9
BC004701



repair deficiency complementation group 6 -



like


Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
3.7
AK010391


F13a1
coagulation factor XIII, A1 subunit
6.2
NM_028784


F2r
coagulation factor II (thrombin) receptor
3.3
AV024285


Fbn1
fibrillin 1
4.0
NM_007993


Fcer1g
Fc receptor, IgE, high affinity I, gamma
16.5
NM_010185



polypeptide


Fcgr3
Fc receptor, IgG, low affinity III
14.4
NM_010188


Fga
fibrinogen, alpha polypeptide
8.6
BC005467


Fgg
fibrinogen, gamma polypeptide
3.1
NM_133862


Fignl1
fidgetin-like 1
6.4
NM_021891


Flna
filamin, alpha
2.9
BM233746


Fn1
fibronectin 1
2.8
BC004724


Fshprh1
FSH primary response 1
2.1
BB258991


Fstl1
follistatin-like 1
4.5
BI452727


Fxyd5
FXYD domain-containing ion transport
8.7
NM_008761



regulator 5


Gch1
GTP cyclohydrolase 1
2.4
NM_008102


Gda
guanine deaminase
16.3
AW911807


Golph2
golgi phosphoprotein 2
2.4
BC011152


H2afx
H2A histone family, member X
2.0
NM_010436


Havcr1
hepatitis A virus cellular receptor 1
7.8
NM_134248


Hells
helicase, lymphoid specific
10.2
NM_008234


Hesx1
homeo box gene expressed in ES cells
2.7
NM_010420


Hmga1
high mobility group AT-hook 1
2.8
NM_016660


Hmmr
hyaluronan mediated motility receptor
3.3
X64550



(RHAMM)


Hp
haptoglobin
5.9
NM_017370


Icam1
intercellular adhesion molecule
10.5
BC008626


Ifitm1
interferon induced transmembrane protein 1
5.2
BC027285


Ifitm3
interferon induced transmembrane protein 3
5.0
BC010291


Il1b
interleukin 1 beta
3.3
BC011437


Il6
interleukin 6
10.3
NM_031168


Inhbb
inhibin beta-B
4.7
BB253137


Isgf3g
interferon dependent positive acting
3.6
NM_008394



transcription factor 3 gamma


Itgam
integrin alpha M
6.5
NM_008401


Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic
2.4
NM_134090



reticulum protein retention receptor 3


Kif11
kinesin family member 11
4.7
BM234447


Kif20a
kinesin family member 20A
2.4
NM_009004


Kif22
kinesin family member 22
8.2
BB251322


Kif2c
kinesin family member 2C
4.0
BB104669


Klf4
Kruppel-like factor 4 (gut)
2.7
BG069413


Lbp
lipopolysaccharide binding protein
4.6
NM_008489


Lcn2
lipocalin 2
57.7
X14607


Lcp1
lymphocyte cytosolic protein 1
16.8
NM_008879


Lepr
leptin receptor
2.4
BM124366


Lgals1
lectin, galactose binding, soluble 1
3.5
AI642438


Lgals3
lectin, galactose binding, soluble 3
3.9
X16834


Lhfp
lipoma HMGIC fusion partner
2.0
AV149705


Lig1
ligase I, DNA, ATP-dependent
3.4
NM_010715


Lilrb3
leukocyte immunoglobulin-like receptor,
7.3
U96693



subfamily B (with TM and ITIM domains),



member 3


Litaf
LPS-induced TN factor
4.5
AV360881


Lmna
lamin A
2.4
AV238225


Lox
lysyl oxidase
7.5
M65143


Lrg1
leucine-rich alpha-2-glycoprotein 1
4.5
NM_029796


Lum
lumican
2.8
AK014312


Ly86
lymphocyte antigen 86
21.0
NM_010745


Lyzs
lysozyme
26.8
AW208566


Lzp-s
P lysozyme structural
22.0
AV066625


Mad2l1
MAD2 (mitotic arrest deficient, homolog)-
3.6
NM_019499



like 1 (yeast)


Marcks
myristoylated alanine rich protein kinase C
2.8
AW546141



substrate


Marcksl1
MARCKS-like 1
4.7
AV110584


Mcm2
minichromosome maintenance deficient 2
3.5
NM_008564



mitotin (S. cerevisiae)


Mcm3
minichromosome maintenance deficient 3
4.9
C80350



(S. cerevisiae)


Mcm4
minichromosome maintenance deficient 4
5.1
BC013094



homolog (S. cerevisiae)


Mcm7
minichromosome maintenance deficient 7
2.7
BB464359



(S. cerevisiae)


Melk
maternal embryonic leucine zipper kinase
4.4
NM_010790


Mfap5
microfibrillar associated protein 5
8.0
NM_015776


Mgp
matrix Gla protein
3.0
NM_008597


Mgst1
microsomal glutathione S-transferase 1
2.1
BI150149


Mmd
monocyte to macrophage differentiation-
2.0
BC021914



associated


Mmp14
matrix metallopeptidase 14 (membrane-
4.5
NM_008608



inserted)


Mmp7
matrix metallopeptidase 7
4.1
NM_010810


Ms4a7
membrane-spanning 4-domains, subfamily
5.5
BC024402



A, member 7


Mt2
metallothionein 2
5.3
AA796766


Mvp
major vault protein
3.5
NM_080638


Myadm
myeloid-associated differentiation marker
2.5
BB500055


Myc
myelocytomatosis oncogene
3.5
BC006728


Myh9
myosin, heavy polypeptide 9, non-muscle
2.4
C80049


Ncf1
neutrophil cytosolic factor 1
6.8
BE370703


Nek2
NIMA (never in mitosis gene a)-related
2.2
C77054



expressed kinase 2


Nek6
NIMA (never in mitosis gene a)-related
2.6
BB528391



expressed kinase 6


Nfkbia
nuclear factor of kappa light chain gene
4.8
AI462015



enhancer in B-cells inhibitor, alpha


Nfkbiz
nuclear factor of kappa light polypeptide
18.1
AB026551



gene enhancer in B-cells inhibitor, zeta


Nrm
nurim (nuclear envelope membrane protein)
2.0
NM_134122


Nuak2
NUAK family, SNF1-like kinase, 2
2.1
AK004737


Nusap1
nucleolar and spindle associated protein 1
7.4
BC009096


Olfml3
olfactomedin-like 3
2.0
NM_133859


Osmr
oncostatin M receptor
7.9
AB015978


P2ry6
pyrimidinergic receptor P2Y, G-protein
5.9
BC027331



coupled, 6


Pbk
PDZ binding kinase
3.5
NM_023209


Pdgfrb
platelet derived growth factor receptor, beta
2.0
AA499047



polypeptide


Pdlim7
PDZ and LIM domain 7
2.8
AK010339


Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
2.0
BG063905


Pea15
phosphoprotein enriched in astrocytes 15
2.3
AI323543


Pfc
properdin factor, complement
5.0
BB800282


Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
5.3
BI684288


Pld4
phospholipase D family, member 4
13.0
BB210623


Plk4
polo-like kinase 4 (Drosophila)
6.0
AI385771


Plp2
proteolipid protein 2
2.5
AK012816


Pltp
phospholipid transfer protein
2.7
NM_011125


Pola1
polymerase (DNA directed), alpha 1
2.9
NM_008892


Pole
polymerase (DNA directed), epsilon
3.3
NM_011132


Prc1
protein regulator of cytokinesis 1
2.6
BC005475


Ptger4
prostaglandin E receptor 4 (subtype EP4)
6.3
BC011193


Ptgfrn
prostaglandin F2 receptor negative
2.2
AV253087



regulator


Ptgs2
prostaglandin-endoperoxide synthase 2
5.3
M94967


Ptprc
protein tyrosine phosphatase, receptor type, C
27.0
NM_011210


Pycard
PYD and CARD domain containing
7.6
BG084230


Racgap1
Rac GTPase-activating protein 1
4.7
NM_012025


Rad51
RAD51 homolog (S. cerevisiae)
8.4
NM_011234


Rcn1
reticulocalbin 1
5.4
NM_009037


Relb
avian reticuloendotheliosis viral (v-rel)
3.7
NM_009046



oncogene related B


Rhob
ras homolog gene family, member B
3.8
BC018275


Ris2
retroviral integration site 2
2.4
AF477481


Rprc1
arginine/proline rich coiled-coil 1
2.2
BC019977


Rras
Harvey rat sarcoma oncogene, subgroup R
2.6
NM_009101


Rrm2
ribonucleotide reductase M2
9.1
NM_009104


S100a10
S100 calcium binding protein A10
2.4
AV295650



(calpactin)


S100a11
S100 calcium binding protein A11
2.6
BC021916



(calizzarin)


S100a6
S100 calcium binding protein A6 (calcyclin)
4.6
NM_011313


S100a8
S100 calcium binding protein A8
7.6
NM_013650



(calgranulin A)


S100a9
S100 calcium binding protein A9
7.1
NM_009114



(calgranulin B)


Saa1
serum amyloid A 1
9.6
NM_009117


Sart2
squamous cell carcinoma antigen
6.8
BM207218



recognized by T cells 2


Scarb2
scavenger receptor class B, member 2
2.2
NM_007644


Sdc1
syndecan 1
3.3
BB533095


Serpina3n
serine (or cysteine) peptidase inhibitor,
5.6
NM_009252



clade A, member 3N


Serpinb6b
serine (or cysteine) peptidase inhibitor,
5.6
NM_011454



clade B, member 6b


Serpine1
serine (or cysteine) peptidase inhibitor,
5.4
NM_008871



clade E, member 1


Sertad4
SERTA domain containing 4
7.2
BQ174721


Sh3bgrl3
SH3 domain binding glutamic acid-rich
5.8
NM_080559



protein-like 3


Shcbp1
Shc SH2-domain binding protein 1
5.4
NM_011369


Sirpb1
signal-regulatory protein beta 1
26.9
AI662854


Slamf9
SLAM family member 9
4.0
NM_029612


Slc15a3
solute carrier family 15, member 3
13.3
NM_023044


Slc25a24
solute carrier family 25 (mitochondrial
5.9
BM230959



carrier, phosphate carrier), member 24


Slc34a2
solute carrier family 34 (sodium phosphate),
6.7
NM_011402



member 2


Slc7a12
solute carrier family 7 (cationic amino acid
3.6
NM_080852



transporter, y+ system), member 12


Smc2l1
SMC2 structural maintenance of
6.1
NM_008017



chromosomes 2-like 1 (yeast)


Smpdl3b
sphingomyelin phosphodiesterase, acid-like
7.6
NM_133888



3B


Socs3
suppressor of cytokine signaling 3
29.6
BB831725


Sp100
nuclear antigen Sp100
2.6
AV284523


Sparc
secreted acidic cysteine rich glycoprotein
2.1
NM_009242


Spbc24
spindle pole body component 24 homolog
2.3
BF577722



(S. cerevisiae)


Stat3
signal transducer and activator of
3.1
AK004083



transcription 3


Tacc3
transforming, acidic coiled-coil containing
4.0
NM_011524



protein 3


Tagln2
transgelin 2
2.2
C76322


Tcf19
transcription factor 19
2.5
BC004617


Tgfb1
transforming growth factor, beta 1
3.2
NM_011577


Tgfbi
transforming growth factor, beta induced
31.0
BB533460


Tgm2
transglutaminase 2, C polypeptide
2.2
BC016492


Timp1
tissue inhibitor of metalloproteinase 1
40.8
BC008107


Tlr2
toll-like receptor 2
9.8
NM_011905


Tmcc2
transmembrane and coiled-coil domains 2
2.1
AK004359


Tmepai
transmembrane, prostate androgen induced
2.4
AV370981



RNA


Tmsb10
thymosin, beta 10
12.3
NM_025284


Tnfrsf12a
tumor necrosis factor receptor superfamily,
2.7
NM_013749



member 12a


Tpm2
tropomyosin 2, beta
2.3
BC024358


Tpm4
tropomyosin 4
3.5
AV122663


Tpx2
TPX2, microtubule-associated protein
3.9
AK011311



homolog (Xenopus laevis)


Tpx2
TPX2, microtubule-associated protein
2.0
AK011311



homolog (Xenopus laevis)


Trip13
thyroid hormone receptor interactor 13
8.2
AK010336


Tuba1
tubulin, alpha 1
3.8
NM_011653


Tubb2 ///
tubulin, beta 2 /// RIKEN cDNA 2410129E14
3.9
BC003475


2410129E14Rik
gene /// similar to TUBULIN BETA CHAIN


/// LOC544939
(T BETA-15)


Tubb5
tubulin, beta 5
3.7
NM_011655


Tubb6
tubulin, beta 6
4.0
NM_026473


Tyrobp
TYRO protein tyrosine kinase binding
17.4
NM_011662



protein


Uhrf1
ubiquitin-like, containing PHD and RING
9.5
BB702754



finger domains, 1


Vasp
vasodilator-stimulated phosphoprotein
3.1
BC015289


Vim
vimentin
17.3
AV147875


Wisp1
WNT1 inducible signaling pathway protein 1
2.9
NM_018865


Zwilch
Zwilch, kinetochore associated, homolog
3.2
BC027435



(Drosophila)


Zyx
zyxin
2.2
NM_011777









OTHER EMBODIMENTS

It is to be understood that while the invention has been described in conjunction with the detailed description thereof, the foregoing description is intended to illustrate and not limit the scope of the invention, which is defined by the scope of the appended claims. Other aspects, advantages, and modifications are within the scope of the following claims.

Claims
  • 1. A method for assessing transplanted tissue for an increased or decreased likelihood of rejection, wherein said method comprises: detecting, from human kidney tissue transplanted into a human, the presence or absence of cells that express guanylate nucleotide binding protein 1 (Gbp1) mRNA or tryptophanyl-tRNA synthetase (Wars) mRNA at an elevated level, wherein said elevated level is at least two times greater than the average level of mRNA expressed in cells from control kidney tissue from a population of humans not rejecting transplanted human kidney tissue,wherein the presence of said cells that express Gbp1 mRNA or Wars mRNA at said elevated level indicates that said human kidney tissue transplanted into a human has an increased likelihood of rejection, andwherein the absence of cells that express Gbp 1 mRNA or Wars mRNA at said elevated level indicates that said human kidney tissue transplanted into a human has a decreased likelihood of rejection.
  • 2. The method of claim 1, wherein said human kidney tissue transplanted into a human is a kidney.
  • 3. The method of claim 1, wherein the presence of said cells that express Gbp 1 mRNA or Wars mRNA at said elevated level is detected, and wherein said method comprises classifying said human kidney tissue transplanted into a human as having an increased likelihood of rejection.
  • 4. A method for assessing transplanted tissue for an increased or decreased likelihood of rejection, wherein said method comprises: detecting, from a sample of human kidney tissue transplanted into a human, the presence or absence of cells that express guanylate nucleotide binding protein 1 (Gbp1) mRNA or tryptophanyl-tRNA synthetase (Wars) mRNA at an elevated level, wherein said elevated level is at least two times greater than the average level of mRNA expressed in cells from control kidney tissue from a population of humans not rejecting transplanted human kidney tissue, wherein said sample of human kidney tissue transplanted into a human was obtained within fifteen days of being transplantedwherein the presence of said cells that express Gbp1 mRNA or Wars mRNA at said elevated level indicates that said human kidney tissue transplanted into a human has an increased likelihood of rejection, andwherein the absence of cells that express Gbp1 mRNA or Wars mRNA at said elevated level indicates that said human kidney tissue transplanted into a human has a decreased likelihood of rejection.
  • 5. The method of claim 4, wherein said human kidney tissue transplanted into a human is a kidney.
  • 6. The method of claim 4, wherein said sample was obtained within ten days of being transplanted.
  • 7. The method of claim 4, wherein said sample was obtained within five days of being transplanted.
  • 8. The method of claim 4, wherein the presence of said cells that express Gbp 1 mRNA or Wars mRNA at said elevated level is detected, and wherein said method comprises classifying said human kidney tissue transplanted into a human as having an increased likelihood of rejection.
  • 9. The method of claim 1, wherein the absence of said cells that express Gbp 1 mRNA or Wars mRNA at said elevated level is detected, and wherein said method comprises classifying said human kidney tissue transplanted into a human as having a decreased likelihood of rejection.
  • 10. The method of claim 4, wherein the absence of said cells that express Gbp 1 mRNA or Wars mRNA at said elevated level is detected, and wherein said method comprises classifying said human kidney tissue transplanted into a human as having a decreased likelihood of rejection.
CROSS-REFERENCE TO RELATED APPLICATIONS

This application claims priority from U.S. Provisional Application Ser. No. 60/683,737, filed May 23, 2005.

US Referenced Citations (3)
Number Name Date Kind
5143854 Pirrung et al. Sep 1992 A
5744305 Fodor et al. Apr 1998 A
20010051344 Shalon et al. Dec 2001 A1
Related Publications (1)
Number Date Country
20060269949 A1 Nov 2006 US
Provisional Applications (1)
Number Date Country
60683737 May 2005 US