Claims
- 1. A method of topical treatment of an inflammatory condition comprising applying to the affected area an anti-inflammatory agent selected from the group consisting of the N-acylaminophenols containing normal aliphatic side chains having from six to twelve carbon atoms in a pharmaceutically acceptable topical vehicle, in an amount sufficient to combat said inflammatory condition.
- 2. The method of claim 1 wherein said acylaminophenol is selected from the group consisting of 4-n-hexanoylaminophenol, 4-n-heptanoylaminophenol, 4-n-octanoylaminophenol, 4-n-nonanoylaminophenol, 4-n-decanoylaminophenol, 4-n-undecanoylaminophenol and 4-n-dodecanoylaminophenol.
- 3. The method of claim 2 wherein said topical vehicle comprises a mixture of propylene glycol and ethanol.
- 4. The method of claim 2 wherein said topical vehicle comprises a mixture of propylene glycol and dimethylsulfoxide.
- 5. The method of claim 3 wherein said acylaminophenol is present in said vehicle in an amount of from about 0.01% to about 10.0% by weight.
- 6. The method of claim 4 wherein said acylaminophenol is present in said vehicle in an amount of from about 0.01% to about 10.0% by weight.
- 7. A composition for the topical treatment of an inflammatory condition comprising a pharmaceutically acceptable topical vehicle selected from the group consisting of nose, ear and eyedrops, creams, lotions, gels, throat lozenges, paint sprays and pastilles containing an anti-inflammatory agent selected from the group consisting of the N-acylaminophenols containing normal aliphatic side chains having from six to twelve carbon atoms, in an amount sufficient to combat said inflammatory condition.
- 8. The composition of claim 7 wherein said acylaminophenol is selected from the group consisting of 4-n-hexanoylaminophenol, 4-n-heptanoylaminophenol, 4-n-octanoylaminophenol, 4-n-nonanoylaminophenol, 4-n-decanoylaminophenol, 4-n-undecanoylaminophenol and 4-n-dodecanoylaminophenol.
- 9. The composition of claim 7 wherein said acylaminophenol is present in said vehicle in an amount of from 0.01% to about 10.0% by weight.
- 10. The composition of claim 7 wherein said vehicle comprises propylene glycol.
- 11. The composition of claim 7 wherein said vehicle comprises propylene glycol and a member selected from the group consisting of ethanol and dimethylsulfoxide.
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a division of our copending application Ser. No. 92,296, filed Nov. 8, 1979, now abandoned.
US Referenced Citations (3)
Foreign Referenced Citations (1)
Number |
Date |
Country |
7.624M |
Jan 1970 |
FRX |
Non-Patent Literature Citations (2)
Entry |
Chem. Abst. 88-58567y, (1978). |
Merds Index-9th Ed., (1976), p. 433. |
Divisions (1)
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Number |
Date |
Country |
Parent |
92296 |
Nov 1979 |
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