Claims
- 1. A transdermal patch prepared using a formulation comprising from about 66 to 99.8% acrylate adhesive, and the compound 3-�4-(butylthio)-1,2,5-thiadiazol-3-yl!-1-azabicyclo�2.2.2!octane in an amount so that the patch contains between about 1 to about 100 mg of the compound.
- 2. A transdermal patch prepared using a formulation comprising the compound 3-�4-(butylthio)-1,2,5-thiadiazol-3-yl!-1-azabicyclo�2.2.2!octane in an amount so that the patch contains between about 1 to about 100 mg of the compound distributed in a matrix comprising a pressure-sensitive adhesive.
- 3. A method for treating a condition associated with modulation of a muscarinic receptor comprising administering 3-�4-(butylthio)-1,2,5-thiadiazol-3-yl!-1-azabicyclo�2.2.2!octane using a transdermal patch.
- 4. A method for treating a condition associated with modulation of a muscarinic receptor comprising administering 3-�4-(butylthio)-1,2,5-thiadiazol-3-yl!-1-azabicyclo�2.2.2!octane transdermally using a patch formulation of claim 1.
- 5. A method of claim 4 wherein the condition is decreased cognition.
- 6. A method of claim 4 wherein the condition is Alzheimer's disease.
- 7. A method of claim 4 wherein an analgesic effect is desired for the treatment of a severely painful condition.
- 8. A method for treating a condition associated with modulation of a muscarinic receptor comprising administering 3-�4-(butylthio)-1,2,5-thiadiazol-3-yl!-1-azabicyclo�2.2.2!octane transdermally using a patch formulation of claim 2.
- 9. A transdermal patch of claim 2 wherein the pressure-sensitive adhesive is an acrylic adhesive.
- 10. A transdermal patch of claim 2 which contains a permeation enhancer.
- 11. A transdermal patch of claim 2 wherein the amount of compound is from 0.1 to 35% by weight of the matrix.
- 12. A transdermal patch of claim 1 wherein the formulation contains from about 80-98% acrylic adhesive.
- 13. A transdermal patch of claim 12 wherein the formulation provides about 1 to about 50 mg of compound per patch.
Parent Case Info
This application is a continuation of application Ser. No. 08/481,016, filed on Jun. 7, 1995, now abandoned which in turn is a continuation-in-part of application Ser. No. 08/390,445, filed on Feb. 17, 1995, now abandoned.
US Referenced Citations (4)
Foreign Referenced Citations (1)
Number |
Date |
Country |
95 05379 |
Feb 1995 |
WOX |
Continuations (1)
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Number |
Date |
Country |
Parent |
481016 |
Jun 1995 |
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Continuation in Parts (1)
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Number |
Date |
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Parent |
390445 |
Feb 1995 |
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