Hopwood, et al. “Genetic Manipulations of Streptomyces: A Laboratory Manual”, The John Innes Foundation, Norwich, England p. 18, p. 21-22, 1985.* |
L.R. Zeph, M.A. Onaga and G. Stotzky, Transduction of Escherichia coli by Bacteriophage P1 in soil., Applied and Environmental Microbiology 54(7) 1731-37, Jun. 1988.* |
Franziska Suss and Siegfried Klaus, Transduction in Streptomyces hygroscopicus mediated by the temperate bacteriophage SH10, Mol. Gen. Genet. 181:552-555, Jan. 1981.* |
Nat L. Sternberg and Russel Maurer, Bacteriophage-mediated generalized transduction in Escherichia coli and Salmonella typhimurium, Methods in Enzymology 204, 18-42, Dec. 1991.* |
Richard B. Goldberg, Robert Bender and Stanley L. Streicher, Direct Selection for P1-sensitive Mutants of Eneteric Bacteria, 118(3):810-14, Jun. 1974.* |
Bedford et al., “A functional chimeric modular polyketide synthase generated via domain replacement,” Chem. Biol., 3:827-831 (1996). |
Borman, “Combinatorial Chemistry,” C&EN, 47-67 (Apr. 6, 1998). |
Brawner et al., “Characterization of Streptomyces promoter sequences using the Escherichia coli galactokinase gene,” Gene, 40:191-201 (1985). |
Cane et al., “Harnessing the Biosynthetic Code: Combinations, Permutations, and Mutations,” Science, 282:63-68 (1998). |
Donadio et al., “An erythromycin analog produced by reprogramming of polyketide synthesis,” Proc. Natl. Acad. Sci. USA, 90:7119-7123 (1993). |
Hopwood et al., Genetic Manipulation of Streptomyces- A Laboratory Manual, The John Innes Foundation, Norwich, UK, pp. 8-9, 72-74, 99-102, 223, 235 (1985). |
Oliynyk et al., “A hybrid modular polyketide synthase obtained by domain swapping,” Chem. Biol., 3:833-839 (1996). |
McDaniel et al., “Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel “unnatural” natural products,” Proc. Natl. Acad. Sci. USA, 96:1846-1851 (1999). |
Ruan et al., “Acyltransferase Domain Substitutions in Erythromycin Polyketide Synthase Yield Novel Erythromycin Derivatives,” J. Bact., 179:6416-6425 (1997). |
Sambrook, Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory Press, p. 9.31-9.55, 2.65 (1989). |
Stuttard, “Generalized Transduction in Streptomyces Species,” Genetics and Molecular Biology of Industrial Microorganisms, Hershberger et al., (eds.), ASM, Washington, D.C. 157-162 (1989). |
Vats et al., “Transductional Analysis of Chloramphenicol Biosynthesis Genes in Streptomyces venezuelae,” J. Bacteriol., 169:3809-3813 (1987). |
McHenney et al., “Gene transfer and transposition mutagenesis in Streptomyces roseosporus: mapping of insertions that influence daptomycin or pigment production”, Microbiology, 142:2363-2373 (1996). |
Ripp et al., “Transduction of freshwater microbial community by a new Pseudomonas aeruginosa generalized transducing phage, UT1”, Molecular Ecology, 3:121-126 (1994). |
Stuttard, “Localized Hydroxylamine Mutagenesis, and Cotransduction of Threonine and Lysine Genes, in Streptomyces venezuelae”, J. Bacteriol, 155(3):1219-1223 (1983). |