Claims
- 1. A method of immunosuppressive treatment, particularly for treatment of allograft rejection in mammals, which comprises administering to a mammal in need thereof 0.4 to 30 mg/kg per day of a compound represented by the formula: ##STR8## wherein: Y is hydrogen and
- Z is hydrogen or --C(O)R,
- where R is lower alkyl or aryl; or a pharmaceutically acceptable salt thereof.
- 2. The method of claim 1 comprising a method of treating cardiac allograft rejection, pancreatic allograft rejection or renal allograft rejection.
- 3. The method of claim 2 wherein Z is hydrogen.
- 4. The method of claim 1 wherein Z is hydrogen.
Parent Case Info
This is a division of pending application Ser. No. 146,883, filed Jan. 22, 1988, now U.S. Pat. No. 4,786,637, which is a continuation-in-part of Ser. No. 008,717, filed Jan. 30, 1987, both incorporated herein by reference.
US Referenced Citations (7)
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Entry |
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Divisions (1)
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Number |
Date |
Country |
Parent |
146883 |
Jan 1988 |
|
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
8717 |
Jan 1987 |
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