Claims
- 1. A method for treating Malaria comprising administering to a human in need of such treatment an effective amount of a compound selected from:
- 2. The method of claim 1 wherein the FPT inhibitor is:
- 3. A method for treating malaria comprising administering to a patient in need of such treatment an effective amount of a compound used in the method of claim 1, in combination with an effective amount of an additional antimalaria agent and/or an additional agent for reversing antimalarial resistance.
- 4. A method for treating malaria comprising administering to a patient in need of such treatment an effective amount of the compound used in the method of claim 2, in combination with an effective amount of an additional antimalaria agent and/or an additional agent for reversing antimalarial resistance.
- 5. The method of claim 3, wherein said compound is administered prior to, concurrent to or subsequent to the administration of said additional antimalaria agent and/or said agent for reversing antimalarial resistance.
- 6. The method of claim 3 wherein said additional antimalaria agent is selected from the group comprising:
a) quinolines, b) folic acid antagonists, c) sulfonamides, and d) antibiotics.
- 7. The method of claim 3 wherein said agent for reversing antimalarial resistance is an inhibitor of multidrug resistance.
- 8. The method of claim 4, wherein said compound is administered prior to, concurrent to or subsequent to the administration of said additional antimalaria agent and/or said agent for reversing antimalarial resistance.
- 9. The method of claim 4 wherein said additional antimalaria agent is selected from the group comprising:
a) quinolines, b) folic acid antagonists, c) sulfonamides, and d) antibiotics.
- 10. The method of claim 4 wherein said agent for reversing antimalarial resistance is an inhibitor of multidrug resistance.
- 11. A compound selected from:
- 12. A pharmaceutical composition comprising an effective amount of a compound used in the method of claim 1, and a pharmaceutically acceptable carrier.
- 13. A pharmaceutical composition comprising an effective amount of the compound used in the method of claim 2, and a pharmaceutical acceptable carrier.
- 14. A pharmaceutical composition comprising an effective amount of a compound of claim 7 and a pharmaceutically acceptable carrier.
- 15. A pharmaceutical composition comprising an effective amount of
(1) a compound used in the method of claim 1;(2) an additional antimalaria agent; and/or (3) an agent for reversing antimalarial resistance.
- 16. The composition of: claim 11 wherein said additional antimalaria agent is selected from the group comprising:
a) quinolines, b) folic acid antagonists, c) sulfoniamides, and d) antibiotics.
- 17. The composition of claim 11 wherein said agent for reversing antimalarial resistance is an inhibitor of multidrug resistance.
- 18. A pharmaceutical composition comprising an effective amount of
(1) the compound used in the method of claim 2;(2) an additional antimalaria agent; and/or (3) an agent for reversing antimalarial resistance.
- 19. The composition of claim 14 wherein said additional antimalaria agent is selected from the group comprising:
a) quinolines, b) folic acid antagonists, c) sulfonamides, and d) antibiotics.
- 20. The composition of claim 14 wherein said agent for reversing antimalarial resistance is an inhibitor of multidrug resistance.
REFERENCE TO RELATED APPLICATIONS
[0001] This application claims the benefit of U.S. Provisional Application Ser. No. 60/263,277 filed Jan. 22, 2001.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60263277 |
Jan 2001 |
US |