Claims
- 1. A method of treating a neurodegencrative or cardiovascular disorder, comprising administering to the subject in need thereof an effective amount of a compound of the following formula:
- 2. The method of claim 1, wherein each of X and Y, independently, is O.
- 3. The method of claim 2, wherein R1 is a C2-8 alkenylene and R2 is a C1-8 alkylene.
- 4. The method of claim 3, wherein R1 is a C2-3 alkenylene and R2 is a C1-3 alkylene.
- 5. The method of claim 4, wherein each of A1 and A2, independently, is aryl, optionally substituted with halogen, —CN, —OH, —SH, —OR3, —SR3, —R3, —R3—OR4, or —NR4R5.
- 6. The method of claim 4, wherein R1 is —CH═CH— and R2 is —CH2—CH2—.
- 7. The method of claim 6, wherein each of A1 and A2, independently, is aryl, optionally substituted with halogen, —CN, —OH, —SH, —OR3, —SR3, —R3, —R3—R4, or —NR4R5.
- 8. The method of claim 7, wherein each of each of A1 and A2, independently, is phenyl optionally substituted with —OH or —SH.
- 9. The method of claim 2, wherein each of A1 and A2, independently, is aryl, optionally substituted with halogen, —CN, —OH, —SH, —OR3, —SR3, —R3, —R3—OR4, or —NR4R5.
- 10. The method of claim 9, wherein each of A1 and A2, independently, is phenyl, optionally substituted with —OH or —SH.
- 11. The method of claim 1, wherein R1 is a C2-8 alkenylene, and R2 is a C1-8 alkylene.
- 12. The method of claim 11, wherein R1 is a C2-3 alkenylene, and R2 is a C1-3 alkylene
- 13. The method of claim 12, wherein R1 is —CH═CH—, and R2 is —CH2—CH2—.
- 14. The method of claim 12, wherein each of A1 and A2, independently, is aryl, optionally substituted with halogen, —CN, —OH, —SH, —OR3, —SR3, —R3, —R3—OR4, or —NR4R5.
- 15. The method of claim 14, wherein A1 is 3,4-dihyoxyphenyl and A2 is phenyl.
- 16. The method of claim 15, wherein R1 is —CH═CH—; R2 is —CH2—CH2—; and each of X and Y, independently, is O.
- 17. The method of claim 1, wherein each of A1 and A2, independently, is aryl, optionally substituted with halogen, —CN, —OH, —SH, —OR3, —SR3, —R3, —R3—OR4, or —NR4R5.
- 18. The method of claim 17, wherein each of A1 and A2, independently, is phenyl, optionally substituted with —OH or —SH.
- 19. A particle of manufacture comprising:
i) a container; ii) an effective amount of a compound, disposed in the container, and having the following formula: 6in which each of R1 and R2, independently, is C1-8 alkylene, C2-8 alkenylene, or deleted; each of A1 and A2, independently, is aryl or heteroaryl, optionally substituted with halogen, —CN, —NO2, —OH, —SH, —OR3, —SR3, —R3, —R3—OR4, —C(O)R3, —S(O)R3, —S(O)2R3, —NR4R5, —C(O)OR3, —C(O)NR4R5, —O(O)CR4, or —NR4(O)CR5; and each of X and Y, independently, is O, S, or NR6, wherein each R3 is C-4 alkyl, and each of R4, R5, and R6, independently, is H or C1-4 alkyl; and iii) a label, disposed on the container and having instructions for treating a neurodegenerative or cardiovascular disorder.
- 20. The particle of manufacture of claim 19, wherein each of X and Y, independently, is O; R1 is a C2-3 alkenylene; R2 is a C1-3 alkylene; and each of A1 and A2, independently, is aryl, optionally substituted with halogen, —CN, —OH, —SH, —OR3, —SR3, —R3, —R3—OR4, or —NR4R5.
- 21. The particle of manufacture of claim 20, wherein R1 is —CH═CH—; R2 is —CH2—CH2—; A1 is 3,4-dihydroxy phenyl; and A2 is phenyl.
CROSS REFERENCE TO RELATED APPLICATION
[0001] Pursuant to 35 USC §119(e)(1), this application claims the benefit of prior U.S. provisional application No. 60/339,215, filed Dec. 10, 2001.
Provisional Applications (1)
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Number |
Date |
Country |
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60339215 |
Dec 2001 |
US |