Claims
- 1. A compound represented by the formula (VII'): ##STR23## where at least one of R.sub.2, R.sub.3 and R.sub.9 represent a group represented by the formula: --A--OR.sub.4 where R.sub.4 represents a hydrogen or a lower alkyl group; and A represents a straight or branched alkylene group having 1 to 6 carbon atoms; and a remaining group or groups are each independently a hydrogen atom; a cyano group; a lower alkyl group which may be substituted by a halogen atom; a carbamoyl group which may be substituted by a lower alkyl group; a cycloalkyl group; or a carboxyl group which may be substituted by a protective group or an eliminatable group which is easily hydrolyzable in a human body, and also when R.sub.9 is --A--OR.sub.4, R.sub.2 and R.sub.3 may be combined with each other to form an alkylene group having 3 to 4 carbon atoms; Z represents a nitrogen atom or a group represented by the formula: C--R.sub.10 where R.sub.10 represents a hydrogen atom, a carboxyl group or a lower alkyl group which may be substituted by a hydroxy group or a lower alkoxy group; and X represents a hydrogen atom, a lower alkyl group, a lower alkoxy group or a halogen atom.
- 2. A compound according to claim 1, wherein the protective group is selected from the group consisting of a diphenylmethyl group, a t-butyl group, a p-nitrobenzyl group and a trimethylsilyl group and the eliminatable group which is easily hydrolyzable in a human body is selected from the group consisting of an acetoxymethyl group, an .alpha.-acetoxyethyl group, a pivaroyloxymethyl group, an ethoxycarbonyloxymethyl group, an .alpha.-methoxycarbonyloxymethyl group, an .alpha.-methoxycarbonyloxyethyl group, an .alpha.- ethoxycarbonyloxyethyl group, a 1-indanyl, a phthalidyl group, and a 5-methyl-2-oxo-1,3-dioxol-4-yl-methyl group.
- 3. A compound according to claim 2, wherein the cycloalkyl group is selected from the group consisting of a cyclopropyl group, a cyclobutyl group, a cyclopentyl group and a cyclohexyl group.
Priority Claims (1)
Number |
Date |
Country |
Kind |
62-196178 |
Aug 1987 |
JPX |
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Parent Case Info
This is a division of application Ser. No. 222,404, filed July 21, 1988.
US Referenced Citations (3)
Foreign Referenced Citations (1)
Number |
Date |
Country |
0150507 |
Aug 1985 |
EPX |
Divisions (1)
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Number |
Date |
Country |
Parent |
222404 |
Jul 1988 |
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