Claims
- 1. A compound of the formula: ##STR23## R.sub.1, and R.sub.2 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 alkyl, halogen, hydroxy, amino, cyano, nitro, trifluoromethyl, trifluoromethoxy, C.sub.1 -C.sub.6 alkoxy, --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1 or 2; or
- R.sub.1 and R.sub.2 independently represent --CONR'R", or --NR'R" where R' and R" independently represent hydrogen or C.sub.1 -C.sub.6 alkyl;
- R.sub.3 is hydrogen or lower alkyl;
- A represents an alkylene group of 2 to 6 carbon atoms optionally substituted with one or more alkyl groups having from 1 to 4 carbon atoms;
- Y represents methylene, oxygen, sulfur, or NH;
- R.sub.4 is biphenyl, naphthyl, 1 or 2 anthracenyl, 1 or 2 biphenylenyl, dibenzofuranyl, dibenzothiophenenyl, fluorenyl, fluorenonyl, anthroquinonyl, 2-quinoxalinyl or azabiphenyl, each of which is optionally substituted independently by up to three groups selected from halogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.4 alkoxy, alkylthio, hydroxy, amino, monoalkylamino, dialkylamino, cyano, nitro, trifluoromethyl or trifluoromethoxy.
- 2. A compound according to claim 1, which is N-{4-(1,2,3,4,4a,5-hexahydropyrazino�2,1-c!�1,4!benzoxazin-2-yl)butyl}-fluorene-2-carboxamide hydrochloride.
- 3. A compound according to claim 1, which is N-{4-(2,3,4,4a,5,6-hexahydro-1H-pyrazino�1,2-a!quinolin-2-yl)butyl}-fluorene-2-carboxamide hydrochloride.
Parent Case Info
This is a continuation of application Ser. No. 08/636,662 filed Apr. 23, 1996, now U.S. Pat. No. 5,688,950.
US Referenced Citations (4)
Non-Patent Literature Citations (1)
Entry |
Boyfield et al., Chem. Abstract 125:104240, 1996. |
Continuations (1)
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Number |
Date |
Country |
Parent |
636662 |
Apr 1996 |
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