Claims
- 1. A compound having the formula: ##STR5## wherein: X is --CH.sub.2 -- or --CH.dbd.CH--;
- R is ##STR6## or a non-toxic pharmaceutically acceptable salt thereof.
- 2. The compound of claim 1 selected from
- N-(2-Thiazolyl)-anti-tricyclo[3.2.2.0.sup.2,4 ]non-8-ene-endo-6,endo-7-dicarboximide; and
- N-(5-Indolinyl-2-one)-anti-tricyclo[4.2.2.0.sup.2,5 ]dec-3,9-diene-endo-7,endo-8-dicarboximide.
- 3. A pharmaceutical composition comprising a therapeutically effective amount in unitary dosage form of a compound having the formula: ##STR7## wherein: X is --CH.sub.2 -- or --CH.dbd.CH--;
- R is ##STR8## or a non-toxic pharmaceutically acceptable salt thereof and a pharmaceutical carrier therefor.
- 4. A method of producing a tranquilizing effect which comprises the administration to a patient in need of such treatment of a therapeutically effective amount of a compound of formula: ##STR9## wherein: X is --CH.sub.2 -- or --CH.dbd.CH--;
- R is ##STR10## or a non-toxic pharmaceutically acceptable salt thereof.
- 5. A method of producing an anticonvulsant effect which comprises the administration to a patient in need of such treatment of a therapeutically effective amount of a compound of formula: ##STR11## wherein: X is --CH.sub.2 -- or --CH.dbd.CH--;
- R is ##STR12## or a non-toxic pharmaceutically acceptable salt thereof.
Parent Case Info
This is a division of application Ser. No. 831,463, filed Sept. 8, 1977, now U.S. Pat. No. 4,132,799, which is a division of application Ser. No. 713,765 filed Aug. 12, 1976, now U.S. Pat. No. 4,061,763, which is a division of application Ser. No. 575,918 filed May 9, 1975, now U.S. Pat. No. 4,006,233, which in turn is a continuation-in-part of application Ser. No. 511,961 filed Oct. 4, 1974, now abandoned.
US Referenced Citations (4)
Number |
Name |
Date |
Kind |
3126395 |
Kitahonoki et al. |
Mar 1964 |
|
3476546 |
Roberts et al. |
Nov 1969 |
|
3903109 |
Dotson, Jr. et al. |
Sep 1975 |
|
3936449 |
Matuo et al. |
Feb 1976 |
|
Foreign Referenced Citations (2)
Number |
Date |
Country |
1111635 |
Jul 1961 |
DEX |
2226397 |
Nov 1974 |
FRX |
Divisions (3)
|
Number |
Date |
Country |
Parent |
831463 |
Sep 1977 |
|
Parent |
713765 |
Aug 1976 |
|
Parent |
575918 |
May 1975 |
|
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
511961 |
Oct 1974 |
|