Claims
- 1. A toothpaste, which comprises at least about 4% by weight, based on the total weight of the toothpaste, of a water-soluble alkali metal tripolyphosphate, a phosphatase enzyme inhibitor consisting of a fluoride ion source in an amount sufficient to supply from about 25 ppm to about 3500 ppm of fluoride ion, a silica or plastics dental abrasive and an orally acceptable vehicle, the toothpaste having a pH of from about 8 to about 10.
- 2. The toothpaste according to claim 1, wherein said water-soluble alkali metal tripolyphosphate is sodium tripolyphosphate.
- 3. The toothpaste according to claim 1, wherein said water-soluble alkali metal tripolyphosphate is present in an amount of from about 4 to 6%, by weight, based on the total weight of the toothpaste.
- 4. The toothpaste according to claim 1, wherein said pH is from about 8 to about 9.
- 5. The toothpaste according to claim 1, wherein said fluoride ion source is an alkali metal fluoride.
- 6. The toothpaste according to claim 5, wherein said alkali metal fluoride is sodium fluoride.
- 7. The toothpaste according to claim 1, wherein said orally acceptable vehicle is an aqueous orally acceptable vehicle.
- 8. The toothpaste according to claim 7, wherein said aqueous orally acceptable vehicle comprises a humectant.
- 9. A toothpaste, which comprises at least about 4%, by weight, based on the total weight of the toothpaste, of a water-soluble alkali metal tripolyphosphate, a phosphatase enzyme inhibitor consisting of a fluoride ion source in an amount sufficient to supply from about 25 ppm to about 3500 ppm of fluoride ion, from about 5 to about 30% by weight, based on the total weight of the toothpaste, of a silica dental abrasive and an orally acceptable vehicle comprising a binder or thickener, the toothpaste having a pH of from about 8 to about 10.
- 10. The toothpaste according to claim 9, wherein said water-soluble alkali metal tripolyphosphate is sodium tripolyphosphate.
- 11. The toothpaste according to claim 9, wherein said water-soluble alkali metal tripolyphosphate is present in an amount of from about 4 to about 6%, by weight, based on the total weight of the toothpaste.
- 12. The toothpaste according to claim 9, wherein said pH is from about 8 to about 9.
- 13. The toothpaste according to claim 9, wherein said fluoride ion source is an alkali metal fluoride.
- 14. The toothpaste according to claim 13, wherein said alkali metal fluoride is sodium fluoride.
- 15. The toothpaste according to claim 9, wherein said orally acceptable vehicle is an aqueous orally acceptable vehicle.
- 16. The toothpaste according to claim 15, wherein said aqueous orally acceptable vehicle comprises a humectant.
- 17. A method of treating humans who are susceptible to the formation of dental calculus, which comprises applying to the teeth of such calculus formers a toothpaste according to claim 1, thereby to inhibit formation of dental calculus.
- 18. A method of treating humans who are susceptible to the formation of dental calculus, which comprises applying to the teeth of such calculus formers a toothpaste according to claim 9, thereby to inhibit formation of dental calculus.
- 19. A method of preparing the toothpaste according to claim 1, which comprises admixing said water-soluble tripolyphosphate in the form of a powder with said phosphatase inhibitor, said dental abrasive and said orally acceptable vehicle, and adding an amount of a base suitable for use in the oral cavity to provide a pH of from about 8 to about 10.
- 20. A method of preparing the toothpaste according to claim 9, which comprises admixing said water-soluble tripolyphosphate in the form of a powder with said phosphatase inhibitor, said silica dental abrasive and said orally acceptable vehicle, and adding an amount of a base suitable for use in the oral cavity to provide a pH of from about 8 to about 10.
Parent Case Info
The present application is a continuation-in-part of our copending application Ser. No. 348,805, filed May 8, 1989 now U.S. Pat. No. 4,923,684, which is incorporated herein by reference thereto.
US Referenced Citations (22)
Foreign Referenced Citations (6)
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Date |
Country |
236290 |
Sep 1987 |
EPX |
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Jan 1988 |
EPX |
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EPX |
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Entry |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
348805 |
May 1989 |
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