BRIEF DESCRIPTION OF THE DRAWINGS
The invention will be described in further detail below with reference to the enclosed drawings, wherein
FIG. 1 is a side view of a preferred embodiment of the tube,
FIG. 2A is a side view of the cap of the present invention,
FIG. 2B is a perspective view from above of the cap of the present invention,
FIG. 3A is a side view of the tube with the cap,
FIG. 3B is a cross section of an embodiment of the tube
FIG. 4 shows the tube and the cap in different positions,
FIG. 5 shows the tube in one position in a compartment of the rack,
FIG. 6 shows the tube in another position in a compartment of the rack,
FIG. 7A shows the bottom of a rack with a tube accommodated in one position,
FIG. 7B shows the bottom of a rack with tubes accommodated in another position.
FIG. 8 shows a section of an embodiment of a rack of the present invention,
FIG. 9A is a perspective view from above of the lid and rack of the present invention,
FIG. 9B is a perspective view from above of the rack with the lid,
FIG. 10A is a side view of the lid and rack,
FIG. 10B is an end view of the lid and rack,
FIG. 11A-C illustrate stacking of lids, racks and a combination of the two,
FIG. 12 is a top view of the rack accommodating 9 tubes according to the present invention,
FIG. 13A illustrates a part of a tool for grabbing and moving a tube according to the present invention, and
FIGS. 13B and 13C schematically illustrate the principle of grabbing the tube with a tool while positioned in a rack.
FIG. 14A-D illustrate an embodiment of a tool for capping and de-capping a tube according to the invention.
DETAILED DESCRIPTION OF THE INVENTION
FIG. 1 shows a preferred embodiment of the tube of the present invention. The tube 1 has a closed bottom end 2 and an open top end 4. The outer surface of the closed bottom end 2 is colored in black to provide for the application of an identification code. The coloring is incorporated in the tube during the manufacturing process. A bead 6 is provided on a flexible part of the tube, i.e. above the solid closed bottom end 2. The bead cooperates with the sides of the rack compartments in a flexible manner to prevent the tubes from being unintentionally removed from the rack. An outer part 8 of the tube seen from a cross-sectional view in a plane perpendicular to the longitudinal extension of the tube is in this embodiment substantially shaped as a square. The part 8 prevents in cooperation with the compartments of the rack in at least one position of the tube in a compartment of the rack the tube from rotating. An edge 9 prevents the tube from dropping further in the rack when the part 8 is fitted in the compartment.
FIGS. 2A and 2B show a side view and a perspective view from above of an embodiment of the cap of the present invention. FIG. 2A shows the cap 10 with the head part 12 and the plug part 14. FIG. 2B is a top view of the cap and shows the head part 12 having a substantially squared depression 16 for interaction with a tool for capping or de-capping the tube. The depression may further be used for interaction with a tool for grabbing and moving the tube with the cap. The depression 16 has four holes 18, one in each side of the substantially square depression for removable interaction with a tool. The cap is provided with an annular recess 20 on the outer surface of the head part for engagement with a tool. Further, the cap 10 comprises a gasket 22 for sealing the tube. The embodiment of the cap shown in FIGS. 2A and 2B further comprises a threading 24 on the plug part 14 of the cap, the end of the plug part 26 being tapered for easy engagement of the cap with the tube. The head part of the cap further comprises a plurality of longitudinal recesses 28 on the outer surface to facilitate manual capping and de-capping.
FIG. 3A shows a side view of an embodiment of the tube with the cap. The tube according to the invention is especially intended for use in handling of samples with volume up to 1 ml, preferably 0.5 or 1 ml. During freezing, a test sample typically expands. To take into account this expansion and at the same time not take up more space than necessary the volume of the tube when the cap is put on is 5-20%, preferably 10% larger than the volume of the un-frozen sample. The preferred internal volume of the tube is thus 1.1 ml or 0.55 ml when the tube is capped.
FIG. 3B schematically shows a cross-section of an embodiment of the tube and cap. A part 29 may be colored to provide for application of an identification code. The part 29 may have an identification code and may be countersunk to prevent it from being scratched. The part 29 may be molded on the tube and then provided with an identification code, or an identification code may be applied to the part 29 prior to attachment of the part to the tube. The part 29 may also be an integrated part of the tube.
FIG. 4 shows an embodiment of the tube and the cap in different positions. The tube 1 has at the open top end an internal threading 30 to facilitate rotational attachment of the cap to the tube.
FIGS. 5 and 6 show an embodiment of the rack according to the invention accommodating a tube in two different positions. The rack 50 comprises a frame 52 with a plurality of compartments 54 for holding a plurality of tubes according to the present invention in one position in a compartment of the rack cf. FIG. 5 and in another position in a compartment of the rack cf. FIG. 6. In the position illustrated in FIG. 5, the tube can rotate substantially freely. The tube may be rotated into at least one position wherein the part 8 fits in the compartment, and gravitation or another force may cause the tube to enter into the position shown in FIG. 6. In the position shown in FIG. 6, the non-circular part 8 of the tube prevents, in cooperation with the compartment, the tube from rotating. The edge 9 on the tube rests on the open top 56 end of the compartment thereby preventing the tube from further insertion in the rack.
The open top end 56 of a compartment is adapted to facilitate insertion and capture of the tube 1 in the compartment. No force has to be applied in the beginning of insertion. At some point during insertion of the tube 1 in a compartment of the rack, the bead 6 has to be forced inside the compartment, whereby the tube 1 and/or the compartment sidewalls are slightly deformed creating a slight resistance against the insertion. When the bead 6 reach the open bottom end (58 on FIG. 7A) of the compartment, the tube with the bead and/or the compartment are allowed to return to its original shape so that the width of the tube at the bead becomes slightly larger than the corresponding width of the compartment so that removal of the tube cannot be performed without application of a force to deform the tube with bead and/or the compartment sufficiently to allow the bead to re-enter the compartment. Also, the protrusions prevent the tubes from falling out of the compartments if the rack is turned upside down. In both positions shown in FIG. 5 and FIG. 6, the bead is positioned below the open bottom end of the compartment, which means that movement of the tube between the two positions shown in FIGS. 5 and 6 is not influenced by the bead.
FIG. 7A shows the rack of FIG. 5 from another point of view. The rack has a plurality of compartments 54 having an open bottom end 58, the rack accommodating a tube according to the invention in the same position as in FIG. 5. The bead 6 has passed the sidewalls of the compartment and thereby prevents the tube from being unintentionally removed from the rack, e.g. falling out of the rack when rack is turned upside down.
Just above the bead 6, an outer circumference of a cross-section in the plane perpendicular to the longitudinal extension of the tube is substantially circular. Because of the circular circumference the tube can be inserted in a compartment of the rack without being rotationally fitted. Further, the tube may rotate substantially freely.
FIG. 7B shows a plurality of tubes accommodated in a rack seen from below. The position of each tube in the rack corresponds to the position of the tube in FIG. 6. When turning the rack upside down, gravity causes the tubes to move into the position which is shown for one tube in FIG. 7A. The bead 6 will prevent the tubes from falling out of the rack. The tubes are provided with an ID-code 59 at the bottom.
FIG. 8 illustrates from below a section of an embodiment of a rack of the present invention. In this embodiment the sidewalls 60 are at the open bottom end of the compartment provided with flexible lamellas 62 to interact in flexible cooperation with the tube. Alternatively only some of the four sidewalls of a compartment may be provided with lamellas. The lamellas may be divided into two or more parts.
FIGS. 9A and 9B schematically illustrates the employment of a lid with the rack of the present invention, FIG. 10A is a side view, and FIG. 10B is an end view of an embodiment of the lid and rack. The lid has a member 70 at each side to, in cooperation with a slot 72 at each side of the rack, prevent unintentional removal of the lid from the rack.
FIG. 11A illustrates the stacking of lids, FIG. 11B the stacking of racks, and FIG. 11C shows the stacking of racks with lids according to the invention.
FIG. 12 is a schematic top view of an embodiment of the rack accommodating 9 tubes with caps 90 according to the present invention. The interspaces 92 between the tubes may be used for a tool for moving the tube from or placing the tube in a compartment of the rack. The tool for moving the tube may in another embodiment engage with the depression 16 in the cap.
FIG. 13A illustrates a part 100 of an embodiment of a tool for grabbing and moving a tube according to the present invention. The tool comprises four arms 110, each arm having a protrusion 112 for engagement with a recess 20 on the head part of a cap. The end 114 of an arm 110 is tapered to facilitate insertion of the tool in the interspaces between the tubes with caps as illustrated in FIG. 13C. The length of the arm from the protrusion 112 to the end 114 of the arm is between 1-25 mm, preferably between 5-15 mm, to provide a firm grip on the tube.
FIGS. 13B and 13C schematically illustrate the principle of operation of an embodiment of the tool for grabbing and inserting or removing the tube with the cap 120. The FIGS. illustrate nine tubes with interspaces 92 positioned in a rack as shown in FIG. 12. In FIG. 13C the four arms 110 of the tool part 100 are positioned in the four interspaces 92 between the nine tubes, the protrusions 112 being on a level with the recess 20 on the head part of the cap. In FIG. 13B the tool has grabbed the tube with the cap by moving the arms 110 towards the center of the tube 120, whereby the protrusions 112 engage with the recess 20 in the head part of the cap. The tube with cap can now be moved from the rack with the tool while the rack is kept in a fixed position.
An embodiment of a tool 130 for capping and de-capping the tube is schematically illustrated in FIG. 14A-D. A longitudinal section is shown on FIGS. 14A and 14C, and a cross section of an embodiment of the tool for capping and de-capping is shown in FIGS. 14B and 14D. The tool employs a ball catch principle. The tool comprises a substantially squared male part 132 for insertion into the depression of the head part of the cap. Two small balls 134 are positioned in the male part separated by a flexible member 136. In an alternative embodiment a rotatable cylinder 138 having a flexible part 140 and a solid part 142 may be provided as illustrated in FIGS. 14B and 14D for keeping the two balls in a flexible (FIG. 14B) and a fixed (FIG. 14D) state. In this way the tool for capping and de-capping the tube may also, in the locked state shown in FIG. 14D, be used for grabbing and inserting or removing the tube with the cap.
Patent Application
20080035642
