TUMOR RADIOCHEMOTHERAPY--EFFECTS OF ULTRASOUND AND HEAT

Information

• Research Project
• 3165143

• ApplicationId

  3165143

• Core Project Number

  R01CA019386

• Full Project Number

  2R01CA019386-14

• Serial Number

  19386

• FOA Number

• Sub Project Id

• Project Start Date

  12/1/1976 - 47 years ago

• Project End Date

  2/28/1995 - 29 years ago

• Program Officer Name

• Budget Start Date

  4/1/1990 - 34 years ago

• Budget End Date

  2/28/1991 - 33 years ago

• Fiscal Year

  1990

• Support Year

  14

• Suffix

• Award Notice Date

  1/1/2999 - 975 years from now

Organizations

• Stanford University

The overall objective of this grant is to provide information and equipment that will facilitate the use of hyperthermia as a clinical tool. The specific aims for the 1985-1989 period are: 1. To determine the response of tumors to drug and heat as a function of pH. 2. To determine mechanisms for the increased interaction between many drugs and heat at low pH. 3. To determine the influence of thermotolerance on drug-heat interactions and to see if heat-drug cross resistance can be used as an assay for drug response. 4. To determine if ultrasound has effects on heat-drug interactions over and above those from heat alone. Drugs: Adriamycin, bleomycin, BCNU, cis-platinum Experimental techniques include: tissue culture, transplantable mouse tumors (RIF, EMT-6, B-16 melanoma), FACS, gel electrophoresis, fluorescent dyes, ultrasound and radiofrequency heating

IC Name

• Activity

  R01

• Administering IC

  CA

• Application Type

  2

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  395

• Ed Inst. Type

  SCHOOLS OF MEDICINE

• Funding ICs

• Funding Mechanism

• Study Section

  RAD

• Study Section Name

  Radiation Study Section

• Organization Name

  STANFORD UNIVERSITY

• Organization Department

• Organization DUNS

  800771545

• Organization City

  STANFORD

• Organization State

  CA

• Organization Country

  UNITED STATES

• Organization Zip Code

  943056203

• Organization District

  UNITED STATES