Patent Application
20200110201
The present invention relates to an optical prism, and more particularly to a two-piece optical prism.
Surface plasmon resonance test is a highly sensitive test currently broadly used in a variety of fields, and has started to invest in biochemistry related tests in recent years, which include, but are not limited to, biomedical testing devices, immune response testing, and antibody-antigen binding dynamic detection. The testing principle is to obtain a surface refractive index change by changing an angle that light is incident in the surface of surface metal, where the surface refractive index change may represent surface molecular bonding, configuration changes, or other possible changes.
Surface plasmon resonance system may be divided into angle, intensity, wavelength and phase detection modality, where the incident light must be carried out with a several adjustments so as to achieve the best test sensitivity if the intensity and phase are used to design. Therefore, the test range and sensitivity will be much limited when the incident angle of the test system cannot be adjusted. In addition, although the wavelength test modality can be carried out at a fixed angle, the test sensitivity is worse than the intensity and phase modalities; the angle detection modality must be carried out with the adjustment of the incident angle.
In Taiwan Patent NO. I480535 issued to the inventor of the present invention, the prism reduces the system volume effectively, but there are still some parts needed to improve, for example, the design can still be further reduced in the combination of it and the detection chip in order to be used conveniently. In addition, the design of the above patent will limit the size and shape of the detection point, which might cause difficulty on a several test designs.
The main object of the present invention is to provide a two-piece optical prism, capable of being used in the surface plasmon resonance optical system for the angle, range adjustment and control of incident light (e.g. laser light), capable of constituting an optical wide-angle, multi-angle incident system to early out the wide-angle, multi-angle scanning detection of surface plasmon resonance, increasing the system dynamic detection range and sensitivity, and further reducing a detection chip.
To achieve the object mentioned above, the present invention is to provide a two-piece optical prism, including a prism having a groove and prism having arc faces, where the prism having a groove has at least one first arc face and groove having at least one second arc face, and the prism having arc faces is placed in the groove of the prism having a groove and has at least one third arc face.
Referring to
The above first arc face 11 is a paraboloid.
The above first arc face 11 is a one-dimensional paraboloid.
The above groove 12 is defined by the two second arc faces 13 and a plane face 14 adapted to connect the two second arc face 13 to each other after a semi-cylinder is cut with a plane surface.
The two sides of the bottom of the above prism 10 respectively have a triangular prism 15 adapted for light reflection.
A prism 20 having arc faces of the present invention, in a second preferred embodiment, is adapted to operate in coordination with the above prism 10 having a groove, the prism 20 has two third arc faces 21.
The above prism 20 is formed by cutting a plane surface on a semi-cylinder to have two third arc faces 21 and plane face 22 adapted to connect the two third arc faces 21 to each other. Referring to
A two-piece optical prism of the present invention, in a third preferred embodiment, includes: a prism 10 having a groove, having two first arc faces 11 and a groove 12 having two second arc faces 13; and a prism 20 having arc faces, placed in the groove 12 of the prism 10 and having two third arc faces 21.
The components and the combination thereof of the present invention has been described as above, and the use features and effects of the present invention will then be described as the following.
Referring to
Light emitted from a light source unit 40 is generated into the light of total internal reflection through the triangular prism 15 and first arc face 11 to the center position of the upper side of the prism 20 to generate surface plasmon resonance so as to detect the sample. Thereafter, the reflected light is generated into the light of total internal reflection through the first arc face 11 on the other side to the triangular prism 14 on the other side to generate the light of total internal reflection to a detection unit 50 for the data analysis of detection signals.
The present invention can be used in the surface plasmon resonance optical system for the angle, range adjustment and control of incident light (e.g. laser light), capable of constituting an optical wide-angle, multi-angle incident system to carry out the wide-angle, multi-angle scanning detection of surface plasmon resonance, increasing the system dynamic detection range and sensitivity, and further reducing a detection chip.
Conventional optical systems are mostly adopted with a mirror coating reflection way and structure to adjust and control an incident angle. But, the present invention uses the triangular prisms 15, the prism 10 having a groove and the prism 20 having arc faces to generate total internal reflection, capable of simplifying manufacture flow, reducing the production cost without needing extra coating process and equipment.
Referring to
