UHMWPE Composite Material for Joint Implants

Information

  • Research Project
  • 8834712
  • ApplicationId
    8834712
  • Core Project Number
    R44AR067628
  • Full Project Number
    2R44AR067628-02
  • Serial Number
    067628
  • FOA Number
    PA-14-071
  • Sub Project Id
  • Project Start Date
    3/6/2015 - 10 years ago
  • Project End Date
    2/28/2018 - 7 years ago
  • Program Officer Name
    WANG, XIBIN
  • Budget Start Date
    3/6/2015 - 10 years ago
  • Budget End Date
    2/29/2016 - 9 years ago
  • Fiscal Year
    2015
  • Support Year
    02
  • Suffix
  • Award Notice Date
    3/6/2015 - 10 years ago
Organizations

UHMWPE Composite Material for Joint Implants

DESCRIPTION (provided by applicant): In this SBIR Phase II project, the mechanical and fatigue-related properties of ultrahigh molecular weight polyethylene (UHMWPE) joint implant materials will be improved by creating a composite material with carbon reinforcements. UHMWPE has long been widely used as wear surfaces in joint implants, and further improvements to its wear resistance have been obtained by cross-linking the polyethylene chains. However, the cross-linking process also degrades some mechanical properties, including toughness, fatigue and yield strengths. Incorporating carbon reinforcements into UHMWPE through the manner described will improve the strength, crack propagation resistance and creep resistance of UHMWPE without compromising its low wear rate. The carbon reinforcements will impart unmatched dimensional stability and toughness to the UHMWPE matrix. Moreover, as the wear surface remains (primarily) UHMWPE, the outstanding wear resistance of UHMWPE will be maintained, if not improved through the mechanical enhancements. Several of these hypotheses were validated during Phase I by preparing composite materials under various formation conditions, and then assessing their mechanical and tribological properties. Should the new UHMWPE materials perform according as expected, the benefits would include longer-lasting implants that are less prone to mechanically-induced failure. The composite materials would therefore require fewer revision procedures and maintain functionality longer, a critical need as life expectancy increases are causing people to outlive their implants.

IC Name
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
  • Activity
    R44
  • Administering IC
    AR
  • Application Type
    2
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    408279
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    846
  • Ed Inst. Type
  • Funding ICs
    NIAMS:408279\
  • Funding Mechanism
    SBIR-STTR RPGs
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    TDA RESEARCH, INC.
  • Organization Department
  • Organization DUNS
    181947730
  • Organization City
    WHEAT RIDGE
  • Organization State
    CO
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    800331916
  • Organization District
    UNITED STATES