ULTRA-COMPACT N-13 AMMONIA GENERATOR FOR PET

Information

• Research Project
• 3502293

• ApplicationId

  3502293

• Core Project Number

  R43HL048969

• Full Project Number

  1R43HL048969-01

• Serial Number

  48969

• FOA Number

• Sub Project Id

• Project Start Date

  8/1/1992 - 32 years ago

• Project End Date

  1/31/1993 - 32 years ago

• Program Officer Name

• Budget Start Date

  8/1/1992 - 32 years ago

• Budget End Date

  1/31/1993 - 32 years ago

• Fiscal Year

  1992

• Support Year

  1

• Suffix

• Award Notice Date

  7/30/1992 - 32 years ago

Organizations

• SCIENCE RESEARCH LABORATORY, INC.

The objective of this program is to develop a dedicated, accelerator-based 13N-ammonia delivery system for positron emission tomography (PET). 13N- ammonia PET scans can accurately measure myocardial blood flow and have been shown to be valuable tools in diagnosing coronary artery disease. 13N-ammonia can also be utilized to measure blood flow in other parts of the body, including the liver, kidney, brain and malignant tumors. The proposed generator will utilize a very low energy Coaxial Cascade Accelerator (CCA) developed at SRL to produce 13N via the 12C(d,n)13N nuclear reaction. The fully shielded acceleratory and 13N-ammonia production system will be housed in a 1.8 m x 1 m x 1.2 m enclosure and will be fully automated with easily operated push-botton controls. The estimated cost of the 13N-ammonia delivery system is comparable to that of a one of a one year supply of 82 Rb, another commonly used blood flow agent.

IC Name

• Activity

  R43

• Administering IC

  HL

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  837

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  SSS

• Study Section Name

• Organization Name

  SCIENCE RESEARCH LABORATORY, INC.

• Organization Department

• Organization DUNS

• Organization City

  SOMERVILLE

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  02143

• Organization District

  UNITED STATES