Claims
- 1. L-carnitine, having a particle size such that it substantially passes through a 100 USBS mesh sieve.
- 2. The L-carnitine of claim 1, which is selected from the group consisting of L-carnitine, salts of L-carnitine, alkanoyl L-carnitines, and salts of alkanoyl L-carnitine .
- 3. The L-carnitine of claim 1, which is selected from the group consisting of L-carnitine chloride, L-carnitine bromide, L-carnitine orotate, L-carnitine acid aspartate, L-carnitine acid phosphate, L-carnitine fumarate, L-carnitine lactate, L-carnitine maleate, L-carnitine acid maleate, L-carnitine acid oxalate, L-carnitine acid sulfate, L-carnitine glucose phosphate, L-carnitine tartrate, L-carnitine acid tartrate, L-carnitine iodate, L-carnitine aspartate, L-carnitine citrate, L-carnitine acid citrate, L-carnitine acid fumarate, L-carnitine glycerophosphate, L-carnitine mucate, L-carnitine orotate, L-carnitine oxalate, L-carnitine sulfate, L-carnitine trichloroacetate, L-carnitine trifluoroacetate, L-carnitine methanesulfonate, L-carnitine pamoate, L-carnitine acid pamoate, C2-8 alkanoyl L-carnitines, C2-8 alkanoyl L-carnitine chloride, C2-8 alkanoyl L-carnitine bromide, C2-8 alkanoyl L-carnitine orotate, C2-8 alkanoyl L-carnitine acid aspartate, C2-8 alkanoyl L-carnitine acid phosphate, C2-8 alkanoyl L-carnitine fumarate, C2-8 alkanoyl L-carnitine lactate, C2-8 alkanoyl L-carnitine maleate, C2-8, alkanoyl L-carnitine acid maleate, C2-8 alkanoyl L-carnitine acid oxalate, C2-8 alkanoyl L-carnitine acid sulfate, C2-8 alkanoyl L-carnitine glucose phosphate, C2-8 alkanoyl L-carnitine tartrate, C2-8, alkanoyl L-carnitine acid tartrate, C2-8, alkanoyl L-carnitine iodate, C2-8 alkanoyl L-carnitine aspartate, C2-8 alkanoyl L-carnitine citrate, C2-8 alkanoyl L-carnitine acid citrate, C2-8 alkanoyl L-carnitine acid fimarate, C2-8 alkanoyl L-carnitine glycerophosphate, C2-8 alkanoyl L-carnitine mucate, C2-8 alkanoyl L-carnitine orotate, C2-8 alkanoyl L-carnitine oxalate, C2-8 alkanoyl L-carnitine sulfate, C2-8 alkanoyl L-carnitine trichloroacetate, C2-8 alkanoyl L-carnitine trifluoroacetate, C2-8 alkanoyl L-carnitine methanesulfonate, C2-8 alkanoyl L-carnitine pamoate, and C2-8 alkanoyl L-carnitine acid pamoate.
- 4. A method of preparing L-carnitine, having a particle size such that it substantially passes through a 100 USBS mesh sieve, comprising:
(1) subjecting L-carnitine having a particle size such that it does not pass through a 100 USBS mesh sieve to size reduction, to obtain size-reduced L-carnitine; and (2) subjecting said size-reduced L-carnitine to sieving through a 100 USBS mesh sieve and selecting that portion which passes through said 100 USBS mesh sieve.
- 5. The method of claim 4, wherein said L-carnitine is selected from the group consisting of L-carnitine, salts of L-carnitine, alkanoyl L-carnitines, and salts of alkanoyl L-carnitine.
- 6. The method of claim 4, wherein said L-carnitine is selected from the group consisting of L-carnitine chloride, L-carnitine bromide, L-carnitine orotate, L-carnitine acid aspartate, L-carnitine acid phosphate, L-carnitine fumarate, L-carnitine lactate, L-carnitine maleate, L-carnitine acid maleate, L-carnitine acid oxalate, L-carnitine acid sulfate, L-carnitine glucose phosphate, L-carnitine tartrate, L-carnitine acid tartrate, L-carnitine iodate, L-carnitine aspartate, L-carnitine citrate, L-carnitine acid citrate, L-carnitine acid fumarate, L-carnitine glycerophosphate, L-carnitine mucate, L-carnitine orotate, L-carnitine oxalate, L-carnitine sulfate, L-carnitine trichloroacetate, L-carnitine trifluoroacetate, L-carnitine methanesulfonate, L-carnitine pamoate, L-carnitine acid pamoate, C2-8 alkanoyl L-carnitines, C2-8 alkanoyl L-carnitine chloride, C2-8 alkanoyl L-carnitine bromide, C2-8 alkanoyl L-carnitine orotate, C2-8 alkanoyl L-carnitine acid aspartate, C2-8 alkanoyl L-carnitine acid phosphate, C2-8 alkanoyl L-carnitine fumarate, C2-8 alkanoyl L-carnitine lactate, C2-8 alkanoyl L-carnitine maleate, C2-8 alkanoyl L-carnitine acid maleate, C2-8 alkanoyl L-carnitine acid oxalate, C2-8 alkanoyl L-carnitine acid sulfate, C2-8, alkanoyl L-carnitine glucose phosphate, C2-8 alkanoyl L-carnitine tartrate, C2-8 alkanoyl L-carnitine acid tartrate, C2-8 alkanoyl L-carnitine iodate, C2-8 alkanoyl L-carnitine aspartate, C2-8 alkanoyl L-carnitine citrate, C2-8 alkanoyl L-carnitine acid citrate, C2-8 alkanoyl L-carnitine acid fumarate, C2-8 alkanoyl L-carnitine glycerophosphate, C2-8 alkanoyl L-carnitine mucate, C2-8 alkanoyl L-carnitine orotate, C2-8 alkanoyl L-carnitine oxalate, C2-8 alkanoyl L-carnitine sulfate, C2-8 alkanoyl L-carnitine trichloroacetate, C2-8 alkanoyl L-carnitine trifluoroacetate, C2-8 alkanoyl L-carnitine methanesulfonate, C2-8 alkanoyl L-carnitine pamoate, and C2-8 alkanoyl L-carnitine acid pamoate.
- 7. A composition, comprising:
(A) L-carnitine having a particle size such that it substantially passes through a 100 USBS mesh sieve; and (B) a pharmaceutically acceptable excipient or carrier.
- 8. The composition of claim 7, wherein said L-carnitine is selected from the group consisting of L-carnitine, salts of L-carnitine, alkanoyl L-carnitines, and salts of alkanoyl L-carnitine.
- 9. The composition of claim 7, wherein said L-carnitine is selected from the group consisting of L-carnitine chloride, L-carnitine bromide, L-carnitine orotate, L-carnitine acid aspartate, L-carnitine acid phosphate, L-carnitine fumarate, L-carnitine lactate, L-carnitine maleate, L-carnitine acid maleate, L-carnitine acid oxalate, L-carnitine acid sulfate, L-carnitine glucose phosphate, L-carnitine tartrate, L-carnitine acid tartrate, L-carnitine iodate, L-carnitine aspartate, L-carnitine citrate, L-carnitine acid citrate, L-carnitine acid fumarate, L-carnitine glycerophosphate, L-carnitine mucate, L-carnitine orotate, L-carnitine oxalate, L-carnitine sulfate, L-carnitine trichloroacetate, L-carnitine trifluoroacetate, L-carnitine methanesulfonate, L-carnitine pamoate, L-carnitine acid pamoate, C2-8 alkanoyl L-carnitines, C2-8 alkanoyl L-carnitine chloride, C2-8 alkanoyl L-carnitine bromide, C2-8 alkanoyl L-carnitine orotate, C2-8 alkanoyl L-carnitine acid aspartate, C2-8 alkanoyl L-carnitine acid phosphate, C2-8 alkanoyl L-carnitine fumarate, C2-8 alkanoyl L-carnitine lactate, C2-8 alkanoyl L-carnitine maleate, C2-8 alkanoyl L-carnitine acid maleate, C2-8 alkanoyl L-carnitine acid oxalate, C2-8 alkanoyl L-carnitine acid sulfate, C2-8 alkanoyl L-carnitine glucose phosphate, C2-8 alkanoyl L-carnitine tartrate, C2-8 alkanoyl L-carnitine acid tartrate, C2-8 alkanoyl L-carnitine iodate, C2-8 alkanoyl L-carnitine aspartate, C2-8 alkanoyl L-carnitine citrate, C2-8 alkanoyl L-carnitine acid citrate, C2-8 alkanoyl L-carnitine acid fumarate, C2-8 alkanoyl L-carnitine glycerophosphate, C2-8 alkanoyl L-carnitine mucate, C2-8 alkanoyl L-carnitine orotate, C2-8 alkanoyl L-carnitine oxalate, C2-8 alkanoyl L-carnitine sulfate, C2-8, alkanoyl L-carnitine trichloroacetate, C2-8 alkanoyl L-carnitine trifluoroacetate, C2-8 alkanoyl L-carnitine methanesulfonate, C2-8 alkanoyl L-carnitine pamoate, and C2-8 alkanoyl L-carnitine acid pamoate.
- 10. The composition of claim 7, which is suitable for oral ingestion.
- 11. The composition of claim 7, which further comprises hydroxycitric acid, Co-enzyme Q10, chromium picolinate, gamma linolenic acid, resveratrol, omega 3 acids, an antioxidant, or a vitamin.
- 12. In a method of treatment, therapy, or prevention, comprising orally administering an effective amount of L-carnitine to a subject in need thereof, the improvement being said L-carnitine has a particle size such that it substantially passes through a 100 USBS mesh sieve.
- 13. The method of claim 12, wherein said L-carnitine is selected from the group consisting of L-carnitine, salts of L-carnitine, alkanoyl L-carnitines, and salts of alkanoyl L-carnitine.
- 14. The method of claim 12, wherein said L-carnitine is selected from the group consisting of L-carnitine chloride, L-carnitine bromide, L-carnitine orotate, L-carnitine acid aspartate, L-carnitine acid phosphate, L-carnitine fumarate, L-carnitine lactate, L-carnitine maleate, L-carnitine acid maleate, L-carnitine acid oxalate, L-carnitine acid sulfate, L-carnitine glucose phosphate, L-carnitine tartrate, L-carnitine acid tartrate, L-carnitine iodate, L-carnitine aspartate, L-carnitine citrate, L-carnitine acid citrate, L-carnitine acid fumarate, L-carnitine glycerophosphate, L-carnitine mucate, L-carnitine orotate, L-carnitine oxalate, L-carnitine sulfate, L-carnitine trichloroacetate, L-carnitine trifluoroacetate, L-carnitine methanesulfonate, L-carnitine pamoate, L-carnitine acid pamoate, C2-8 alkanoyl L-carnitines, C2-8-alkanoyl L-carnitine chloride, C2-8 alkanoyl L-carnitine bromide, C2-8 alkanoyl L-carnitine orotate, C2-8 alkanoyl L-carnitine acid aspartate, C2-8 alkanoyl L-carnitine acid phosphate, C2-8 alkanoyl L-carnitine fumarate, C2-8 alkanoyl L-carnitine lactate, C2-8 alkanoyl L-carnitine maleate, C2-8 alkanoyl L-carnitine acid maleate, C2-8 alkanoyl L-carnitine acid oxalate, C2-8 alkanoyl L-carnitine acid sulfate, C2-8 alkanoyl L-carnitine glucose phosphate, C2-8 alkanoyl L-carnitine tartrate, C2-8 alkanoyl L-carnitine acid tartrate, C2-8 alkanoyl L-carnitine iodate, C2-8 alkanoyl L-carnitine aspartate, C2-8 alkanoyl L-carnitine citrate, C2-8, alkanoyl L-carnitine acid citrate, C2-8 alkanoyl L-carnitine acid fumarate, C2-8 alkanoyl L-carnitine glycerophosphate, C2-8 alkanoyl L-carnitine mucate, C2-8 alkanoyl L-carnitine orotate, C2-8 alkanoyl L-carnitine oxalate, C2-8 alkanoyl L-carnitine sulfate, C2-8 alkanoyl L-carnitine trichloroacetate, C2-8 alkanoyl L-carnitine trifluoroacetate, C2-8 alkanoyl L-carnitine methanesulfonate, C2-8 alkanoyl L-carnitine pamoate, and C2-8 alkanoyl L-carnitine acid pamoate.
Parent Case Info
[0001] This application claims priority to U.S. Provisional Application No. 60/152,240 filed on Sep. 3, 1999, and U.S. Provisional Application No. 60/158,245 filed on Oct. 8, 1999.
Provisional Applications (2)
|
Number |
Date |
Country |
|
60152240 |
Sep 1999 |
US |
|
60158245 |
Oct 1999 |
US |
Continuations (1)
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Number |
Date |
Country |
Parent |
09653861 |
Sep 2000 |
US |
Child |
10073978 |
Feb 2002 |
US |