U.S.-Argentina Cooperative Research: Localized Stimulation of Compartmentalized cAMP Response

Information

  • NSF Award
  • 9116011
Owner
  • Award Id
    9116011
  • Award Effective Date
    4/15/1992 - 32 years ago
  • Award Expiration Date
    12/31/1995 - 28 years ago
  • Award Amount
    $ 20,000.00
  • Award Instrument
    Standard Grant

U.S.-Argentina Cooperative Research: Localized Stimulation of Compartmentalized cAMP Response

This award from the U.S.-Argentina Cooperative Science Program supports research in biology to be conducted by Dr. Jose R. Lemos of the Worcester Foundation for Experimental Biology, Dr. Roger Y. Tsien of the University of California, San Diego and Dr. Ernesto J. Podesta of the University of Buenos Aires, Argentina. The project focuses on the fact that the interaction of a peptide with the appropriate receptors on a cell surface, and the subsequent signal transduction are some of the most important steps in the mechanism of peptide hormone action. The approach will allow study of the mechanism of peptide hormone stimulation of steroid secretion. The aim of the project is to understand stimulus- secretion coupling. Using state-of-the-art techniques, the investigators will examine the compartmentalization of the cAMP-mediated response of individual Leydig cells to hormonal stimulation. The award will allow continuation of a productive U.S.-Argentina collaboration.

  • Program Officer
    Frank D. Anger
  • Min Amd Letter Date
    4/8/1992 - 32 years ago
  • Max Amd Letter Date
    8/30/1995 - 29 years ago
  • ARRA Amount

Institutions

  • Name
    Worcester Foundation for Biomedical Research, Inc.
  • City
    Shrewsbury
  • State
    MA
  • Country
    United States
  • Address
    222 Maple Avenue
  • Postal Code
    015452732
  • Phone Number
    5088428921

Investigators

  • First Name
    Jose
  • Last Name
    Lemos
  • Start Date
    4/15/1992 12:00:00 AM

FOA Information

  • Name
    Other Applications NEC
  • Code
    99