U.S.-France Cooperative Research: Role of Pregnancy on Maternal Immune Tolerance

Information

• NSF Award
• 9603410

Owner

• NATIONAL JEWISH HEALTH

• Award Id

  9603410

• Award Effective Date

  4/1/1997 - 27 years ago

• Award Expiration Date

  3/31/2000 - 24 years ago

• Award Amount

  $ 15,000.00

• Award Instrument

  Standard Grant

This three-year award for U.S.-France cooperative research in immunology involves David Nemazee of the National Jewish Center for Immunology and Respiratory Medicine and Colette Kanellopoulos-Langevin of the Institut Jacques Monod, Universite Paris 7, Paris, France. The objective of the research is to investigate the role of pregnancy on maternal immune tolerance. Understanding how the mother tolerates the fetus, which represents a natural graft bearing foreign paternal antigens, is a central goal. The project uses transgenic mice in studying this problem and takes advantage of the French investigator's expertise on mouse development. The research will advance fundamental understanding of how fetal-specific B-cells of the mother are regulated by fetal antigen and how facultative tolerance to non-self tissue can be generated during pregnancy.

• Program Officer

  Jennifer Slimowitz Pearl

• Min Amd Letter Date

  3/26/1997 - 27 years ago

• Max Amd Letter Date

  3/26/1997 - 27 years ago

• ARRA Amount

• Name

  National Jewish Health

• City

  Denver

• State

  CO

• Country

  United States

• Address

  1400 Jackson Street

• Postal Code

  802062761

• Phone Number

  3033981078

• First Name

  David

• Last Name

  Nemazee

• Email Address

  nemazeed@njc.org

• Start Date

  3/26/1997 12:00:00 AM