U.S.-Mexico Cooperative Research: Effects of Prostaglandin B1 Oligomers on Membrane Ca 2+-ATPase

Information

• NSF Award
• 8803662

Owner

• MCP Hahnemann University

• Award Id

  8803662

• Award Effective Date

  8/15/1988 - 35 years ago

• Award Expiration Date

  1/31/1992 - 32 years ago

• Award Amount

  $ 9,072.00

• Award Instrument

  Standard Grant

This award will suport cooperative research between Prof. Thomas Devlin of Hahnemann University School of Medicine and Prof. Salvador Uribe of the National Autonomous University of Mexico (UNAM) in Mexico City. The investigators intend to study the effect of prostaglandin polymers on calcium ATPase in 2 systems: the human red blood cell plasma membrane and the sarcolemma of the rabbit heart. They will also study the effect of PG polymers on the metabolism of rat hepatocytes. The work on enzymes from human erithrocytes is to be performed at Hahnemann University while the work on rabbit heart sarcolemma and muscle sarcoplasmic reticulum will be carried out at UNAM. The investigators are capable and the collaboration continues an ongoing effort. These studies should add to our understanding of the mechanisms of action of the PGB oligomers and calcium ATPase and their role in maintaining intracellular calcium levels.

• Program Officer

  Harold Stolberg

• Min Amd Letter Date

  8/9/1988 - 35 years ago

• Max Amd Letter Date

  8/9/1988 - 35 years ago

• ARRA Amount

• Name

  MCP Hahnemann University

• City

  Philadelphia

• State

  PA

• Country

  United States

• Address

  3201 Arch Street, Suite 100

• Postal Code

  191042760

• Phone Number

  2158955849

• First Name

  Thomas

• Last Name

  Devlin

• Start Date

  8/15/1988 12:00:00 AM

• Name

  Health

• Code

  203000