Claims
- 1. A light application unit for a photodynamic diagnosis and for a photodynamic therapy of non-malignant diseases of a parodontium and of a tooth of a living being, optionally a pharmaceutical preparation allowing said photodynamic diagnosis and said photodynamic therapy was previously applied to said living being, comprising
a light source for generating a light with a wavelength spectrum lying at least in a visible region, a focusing unit for focusing said light, at least one element arrangeable in a light beam path of said light generated by said light source, said at least one element altering a spectral property of said light, and at least one wave guide for transmitting said light emitted from said light source to a distal emitting end of said at least one wave guide, said at least one wave guide is configured rigidly in at least a distal region for handling, and said at least one wave guide being curved in a distal end section thereof.
- 2. The light application unit of claim 1, wherein two wave guides are provided.
- 3. The light application unit of claim 2, wherein said two wave guides run adjacent to another, and wherein an emitting end face of one of said two wave guides projects in a distal direction beyond an emitting end face of the other of said two wave guides.
- 4. The light application unit of claim 3, wherein one of said two wave guides is arranged to be axially shiftable relative to the other wave guide.
- 5. The light application unit of claim 4, wherein said shiftable wave guide is disposed within a tubular channel.
- 6. The light application unit of claim 5, wherein said tubular channel is configured for additionally supplying media.
- 7. The light application unit of claim 1, wherein said at least one element arrangeable in said light beam path is configured as a filter.
- 8. The light application unit of claim 7, wherein different filters are arranged to be brought into or out of said light beam path.
- 9. The light application unit of claim 1, wherein a filter is provided which can be disposed in a view direction of an operator handling said light application unit and a treatment area of said parodontium, wherein said filter blocks a fluorescence excitation light emitted by said light source, however transmits fluorescence emission light, emitted from said parodontium and said tooth of said living being illuminated by said light application unit.
- 10. The light application unit of claim 1, wherein said at least one wave guide is composed of a plurality of light transmitting individual fibers.
- 11. The light application unit of claim 1, wherein said at least one wave guide is formed of a single light transmitting fiber.
- 12. The light application unit of claim 1, wherein a further wave guide is provided, which transmits light in a proximal direction from a region irradiated by said light application unit.
- 13. The light application unit of claim 12, wherein said further wave guide is a part of a multi-fiber wave guide transmitting light to a distal direction.
- 14. The light application unit of claim 13, wherein said light transmitted proximally by said further wave guide is supplied to an evaluation unit.
- 15. The light application unit of claim 14, wherein said evaluation unit comprises at least one of a spectral analysis unit, a camera, a spectrally selective sensitive photo element.
- 16. The light application unit of claim 1, wherein said at least one wave guide is provided with a spacer at a distal end thereof.
- 17. The light application unit of claim 1, wherein said at least one wave guide is provided with a diffuser at a distal end thereof.
- 18. The light application unit of claim 17, wherein said diffuser is configured as a spherical convex expansion of said distal end of said wave guide.
- 19. The light application unit of claim 18, wherein said diffuser is configured of a light-permeable material with optically controllable properties.
- 20. The light application unit of claim 19, wherein said diffuser is formed as an inflatable balloon arranged at said distal end of said wave guide, which balloon is inflatable via a channel.
- 21. The light application unit of claim 1, wherein an ultrasound transmission element is provided, through which ultrasound can be transmitted to said distal end of said wave guide.
- 22. The light application unit of claim 21, wherein an ultrasound excitation unit is provided to be coupled with said ultrasound transmission element.
- 23. The light application unit of claim 22, wherein said wave guide is configured as an element for transmitting said ultrasound.
- 24. The light application unit of claim 1, wherein said light source has a large blue component in the region of 400 nm.
- 25. The light application unit of claim 24, wherein said light source comprises a xenon discharge lamp.
- 26. The light application unit of claim 1, wherein a housing is provided having a pistol-like handle, and a tube section extending from said housing, said at least one wave guide being disposed within said tube section.
- 27. The light application unit of claim 26, wherein said tube section is configured to be coupled to said housing and can be removed from said housing.
- 28. The light application unit of claim 27, wherein said tube section is formed to taper conically over at least one portion of its length towards said distal end of said wave guide.
- 29. The light application unit of claim 28, wherein a further filter is provided which can be disposed in a view direction of an operator handling said light application unit to a treatment area of said parodontium, said further filter is mounted to said tube section.
- 30. The light application unit of claim 29, wherein said further filter mounted to said tube section is mounted to be shiftable and pivotal.
- 31. The light application unit of claim 1, wherein a canula is provided, through which canula said pharmaceutical preparation can be applied to said living being.
- 32. The light application unit of claim 1, further comprising an apparatus for applying said pharmaceutical preparation to said living being for performing a photodynamic diagnosis and a photodynamic therapy, said apparatus comprising, at least two chambers, 5-amino levulinic acid or a derivative thereof is received in a first chamber, and a carrier substance for said compounds in said first chamber is present in a second chamber, a mechanism for connecting said two chambers and mixing the components contained within said two chambers shortly before applying said pharmaceutical preparation to said living being, and a canula for passing said pharmaceutical preparation to a tissue area of a parodontium or a tooth of said living being.
- 33. A pharmaceutical preparation comprising a compound selected from the group consisting of 5-amino levulinic acid and derivatives thereof for use in a photodynamic diagnosis and in a photodynamic therapy of non-malignant diseases of a parodontium and a tooth of a living being having applied said pharmaceutical preparation.
- 34. The pharmaceutical preparation of claim 33, used for performing photodynamic diagnosis and photodynamic therapy of non-malignant diseases selected from the group consisting of parodontitis, parodontopathies, caries, bacteria located on a surface tissue of the parodontium and bacteria within a tissue of the parodontium.
- 35. The pharmaceutical preparation of claim 33, wherein said 5-amino levulinic acid or said derivative thereof is used in a carrier substance selected from the group consisting of hydrogels, in particular an alginate gel, an oil-in-water emulsion, and a buffer solution having pH of 5 to 6.
- 36. The pharmaceutical preparation of claim 33, wherein said derivate of said 5-amino levulinic acid is an ester of 5-amino levulinic acid.
- 37. The pharmaceutical preparation of claim 36, wherein said ester of said 5-amino levulinic acid is selected from the group of methyl ester, ethyl ester and hexyl ester.
- 38. The pharmaceutical preparation of claim 33, wherein said 5-amino levulinic acids or its derivative is used in a carrier substance, said carrier substance and said 5-amino levulinic acid or its derivate are mixed shortly before applying said pharmaceutical preparation to said living being.
- 39. An apparatus for applying a pharmaceutical preparation to a living being for performing a photodynamic diagnosis and a photodynamic therapy of non-malignant diseases of a parodontium and of a tooth, said apparatus comprising, at least two chambers, 5-amino levulinic acid or a derivative thereof is received in a first chamber, and a carrier substance for said compounds in said first chamber is present in a second chamber, a mechanism for connecting said two chambers and mixing the components contained within said two chambers shortly before applying said pharmaceutical preparation to said living being, and a canula for passing said pharmaceutical preparation to a tissue area of a parodontium or a tooth of said living being.
Priority Claims (1)
Number |
Date |
Country |
Kind |
198 27 417.3 |
Jun 1998 |
DE |
|
Parent Case Info
[0001] This is a continuation of pending International Application PCT/EP99/04242 filed on Jun. 18, 1999 which designates the U.S.
Continuations (1)
|
Number |
Date |
Country |
Parent |
PCT/EP99/04242 |
Jun 1999 |
US |
Child |
09741204 |
Dec 2000 |
US |