Claims
- 1. Method for treating glaucoma comprising topically administering to eyes of a patient with glaucoma an effective amount of D-carazolol or a pharmaceutically acceptable salt thereof, said D-carazolol substantially free of L-carazolol.
- 2. Method of claim 1, wherein said D-carazolol is administered in the form of eyedrops.
- 3. Method of claim 1, wherein said D-carazolol is administered in the form of a composition combined with a pharmaceutically acceptable carrier.
- 4. Method of claim 3, wherein said pharmaceutically acceptable carrier is an isotonic solution.
- 5. Method of claim 3, wherein said D-carazolol comprises 0.001 to 0.1% by weight of said composition.
- 6. Method of claim 1, wherein said pharmaceutically acceptable salt is a hydrochloric acid, hydrobromic acid, phosphoric acid, sulphuric acid, acetic acid, salicyclic acid, citric acid, benzoic acid, napthoic acid, 2-acetoxybenzoic acid, adipic acid, or maleic acid salt.
- 7. Method of claim 3, wherein said composition further comprises a preserving agent.
- 8. Method of claim 7, wherein said preserving agent is bensyl alcohol, bensalkonium chloride, phenol, or chlorohexidine acetate.
- 9. Method of claim 3, wherein said composition further comprises a solubilizing agent.
- 10. Method of claim 9, wherein said solubilizing agent is polyethylene glycol, polyvinylpyrolidone, or glycerol.
- 11. Method of claim 3, wherein said composition further comprises a buffer at pH 7.
- 12. Method of claim 11, wherein said buffer is acetic acid/sodium citrate, or sodium ethylenediaminetetraacetate.
- 13. Method for treating glaucoma comprising topically administering to eyes of a patient with glaucoma an effective amount of a composition containing from 0.005 to 0.03% by weight of D,L-carazolol or a pharmaceutically acceptable salt thereof.
Priority Claims (1)
Number |
Date |
Country |
Kind |
3300933 |
Jan 1983 |
DEX |
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Parent Case Info
This is a continuation of application Ser. No. 568,437, filed 1-5-84, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4503067 |
Wiedemann |
Mar 1985 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
1369580 |
Oct 1974 |
GBX |
Non-Patent Literature Citations (4)
Entry |
The Merck Index, 9th ed. (1976), No. 9170. |
The Merck Index, 10th ed., (1983), No. 1753. |
AMA Drug Evaluations, 5th ed., (4-1983), p. 457. |
Manalan et al., Circ. Res. 49: 326-336 (1981). |
Continuations (1)
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Number |
Date |
Country |
Parent |
568437 |
Jan 1984 |
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