Claims
- 1. A method of treating a patient suffering from diabetic and/or dysmetabolic nephropathy comprising administering to the patient L-carnitine or its alkanoyl derivative, in which the alkanoyl is a straight or branched aliphatic residue with from 2 to 8 carbon atoms, or in the form of a pharmaceutically acceptable salt.
- 2. The method according to claim 1, in which the alkanoyl L-carnitine is propionyl L-carnitine.
- 3. The method according to claim 1, in which deterioration of kidney function is impeded or retarded.
- 4. The method according to claim 3, in which the need for dialytic replacement treatment or for an organ transplant is delayed.
- 5. The method according to claim 4, in which organ damage induced by the dysmetabolic disease is reduced at the renal glomerule level.
Priority Claims (1)
Number |
Date |
Country |
Kind |
RM99A0480 |
Jul 1999 |
IT |
|
Parent Case Info
This application is the US national phase of international application PCT/ITT00/00288 filed Jul. 12, 2000, which designated the US.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
PCT/IT00/00288 |
|
WO |
00 |
Publishing Document |
Publishing Date |
Country |
Kind |
WO01/07038 |
2/1/2001 |
WO |
A |
US Referenced Citations (7)
Foreign Referenced Citations (3)
Number |
Date |
Country |
98 01128 |
Jan 1998 |
WO |
98 33494 |
Aug 1998 |
WO |
99 06039 |
Feb 1999 |
WO |
Non-Patent Literature Citations (1)
Entry |
Boehles H et al; “The Influence of L Carnitine Supplementation on Lipid Metabolism in Rrenal Insufficient Children on Hemodialysis”; Infusionstherapie; vol. 18, No. 5; 1991; pp. 224-226; XP001011523. |