Claims
- 1. A method for preventing tanning and for lightening human skin and hair which comprises applying to the hair and skin a mixture of at least two micronized organic UV filters.
- 2. A method according to claim 1, wherein the mixtures of organic UV filters are chosen from at least 2 classes of organic UV filters selected from the group consisting of: triazine or benzotriazole derivatives, amides containing a vinyl group, cinnamic acid derivatives, sulfonated benzimidazoles, Fischer base derivatives, diphenylmalonitriles, oxalylamides, camphor derivatives, diphenylacrylates, paraaminobenzoic acid (PABA) and derivatives thereof, salicylates and benzophenones.
- 3. A method according to claim 1, wherein the organic UV filters are chosen from triazine derivatives of the formula in whichR1, R2 and R3, independently of one another, are hydrogen; OH; C1-C10alkoxy; —NH2; —NH—R4; —N(R4)2; —OR4, R4 is C1-C5alkyl; phenyl; phenoxy; anilino; pyrrolo, wherein phenyl, phenoxy, anilino or pyrrolo may be unsubstituted or substituted by one, two or three OH groups, carboxyl, —CO—NH2, C1-C5alkyl or C1-C5alkoxy; a methylidenecamphor group; a group of the formula —(CH═CH)mC(═O)—OR4; a group of the formula or the corresponding alkali metal, ammonium, mono-, di- or tri-C1-C4alkylammonium, mono-, di- or tri-C2-C4alkanolammonium salts, or C1-C3alkyl esters thereof; or a radical of the formula (1a) R5 is hydrogen; unsubstituted C1-C5alkyl or C1-C5alkyl substituted by one or more OH groups; C1-C5alkoxy; amino; mono- or di-C1-C5alkylamino; M; a radical of the formula R′, R″ and R′″, independently of one another, are unsubstituted C1-C14alkyl or C1-C14alkyl substituted by one or more OH groups; R6 is hydrogen; M; C1-C5alkyl; or a radical of the formula —(CH2)m2—O—T1; M is a metal cation; T1 is hydrogen; or C1-C8alkyl; m is 0 or 1 m2 is 1 to 4; and m3 is 2to 14.
- 4. A method according to claim 1, wherein the organic UV filters are chosen from triazine derivatives of the formula in whichR7 and R8, independently of one another, are C1-C18alkyl; C2-C18alkenyl; a radical of the formula —CH2—CH(—OH)—CH2—O—T1; or R7 and R8 are a radical of the formula (2a) R9 is the direct bond; a straight-chain or branched C1-C4alkylene radical or a radical of the formula —Cm1H2m1—O—; R10, R11 and R12, independently of one another, are C1-C18alkyl; C1-C18alkoxy or a radical of the formula R13 is C1-C5alkyl; m1 is 1 to 4; p1 is 0 to 5; A1 is a radical of the formula or of the formula R14 is hydrogen; C1-C10alkyl, —(CH2CHR16—O)n1—R15; or a radical of the formula —CH2—CH(—OH)—CH2—O—T1; R15 is hydrogen; M; C1-C5alkyl; or a radical of the formula —(CH2)m2—O—(CH2)m3—T1; R16 is hydrogen; or methyl; T1 is hydrogen; or C1-C8alkyl; Q1 is C1-C18alkyl; M is a metal cation; m2 and m3, independently of one another, are 1 to 4; and n1 is 1 to 16.
- 5. A method according to claim 1, wherein the organic UV filters are chosen from triazine derivatives of the formula in whichR21 is C1-C30alkyl; C2-C3alkenyl; unsubstituted C5-C12cycloalkyl or C5-C12cycloalkyl mono- or polysubstituted by C1-C5alkyl; C1-C5alkoxy-C1-C12alkyl; amino-C1-C12alkyl; C1-C5monoalkylamino-C1-C12alkyl; C1-C5dialkylamino-C1-C12alkyl; a radical of the formula (34a) or (3b) in which R22, R23 and R24, independently of one another, are hydrogen, —OH; C1-C30alkyl, C2-C30alkenyl, R25 is hydrogen; or C1-C5alkyl; m1 is 0 or 1; and n1 is 1 to 5.
- 6. A method according to claim 1, wherein the organic UV filters are chosen from triazine derivatives of the formula r and s, independently of one another, are 0 to 20.
- 7. A method according to claim 1, wherein the organic UV filters are chosen from triazine derivatives of the formula
- 8. A method according to claim 1, wherein the organic UV filters are chosen from triazine derivatives of the formula
- 9. A method according to claim 1, wherein the organic UV filters are chosen from triazine derivatives of the formula
- 10. A method according to claim 1, wherein the organic UV filters are chosen from triazine derivatives of the formula R27, R28 and R29, independently of one another, are a radical of the formula R30 is hydrogen; alkali metal; an ammonium group —N(R33)4, R33 is hydrogen; C1-C5alkyl; or a polyoxyethylene radical which has 1 to 10 ethylene oxide units and the terminal OH group can be etherified with a C1-C5alcohol; R31 is hydrogen; —OH; or C1-C6alkoxy; R32 is hydrogen or —COOR30; and n is 0 or 1.
- 11. A method according to claim 1, wherein the organic UV filters are chosen from benzotriazole derivatives of the formula (26) in whichT1 is C1-C5alkyl or hydrogen; and T2 is C1-C5alkyl or phenyl-substituted C1-C5alkyl.
- 12. A method according to claim 1, wherein the organic UV filters are chosen from benzotriazole derivatives of the formula T2 is C1-C4alkyl, isooctyl or phenyl-substituted C1-C5alkyl.
- 13. A method according to claim 1, wherein the organic UV filters are chosen from Fischer base aldehydes of the formula R41 is hydrogen; C1-C5alkyl; C1-C18alkoxy; or halogen; R42 is C1-C8alkyl; C5-C7cycloalkyl; or C6-C10aryl; R43 is C1-C18alkyl or a radical of the formula (32a) R44 is hydrogen; or a radical of the formula R45 is C1-C18alkoxy; or a radical of the formula R46 and R47, independently of one another, are hydrogen; or C1-C5alkyl; R48 is hydrogen; C1-C5alkyl; C5-C7cycloalkyl; phenyl; phenyl-C1-C3alkyl; R49 is C1-C18alkyl; X is Hal; a radical of the formula (32c) or
- 14. A method according to claim 1, wherein the organic UV filters are chosen from compounds of the formula in whichR50, R51, R52, R53, R54, independently of one another, are hydrogen, C1-C8alkyl or C5-C10cycloalkyl; R55 is hydrogen; C1-C8alkyl; C5-C10cycloalkyl; hydroxyl; C1-C8alkoxy; COOR56; or CONR57R58; R56, R57 and R58, independently of one another, are hydrogen or C1-C6alkyl; X and Y, independently of one another, are hydrogen, —CN; CO2R59; CONR59R60; or COR59; where the radicals X and Y may additionally be a C1-C8alkyl radical, a C5-C10alkyl radical or a heteroaryl radical having 5 to 6 ring atoms, where, in addition, X and Y or R50 together with one of the radicals X and Y can represent the radical to complete a 5- to 7-membered ring which may contain up to 3 heteroatoms, where the ring atoms may be substituted by exocyclically double-bonded oxygen and/or C1-C8alkyl and/or C5-C10cycloalkyl radicals, and/or may contain C═C double bonds; Z is hydrogen; ammonium; alkali metal ion; or the cation of an organic nitrogen base used to neutralize the free acid group; R59 and R60, independently of one another, are hydrogen, C1-C8alkyl or C5-C10cycloalkyl; and n and m, independently of one another, are 0 or 1.
- 15. A process for the preparation of mixtures of organic UV filters according to claim 1, which comprises thoroughly mixing the UV filters present in micronized form together.
- 16. A process for the preparation of mixtures of organic UV filters according to claim 1, which comprises micronizing the organic UV filters as mixtures of at least two individual substances.
- 17. A process for the preparation of mixtures of organic UV filters according to claim 1, which comprises melting together at least two individual substances, cooling the melt, and then subjecting the resulting composite to a micronization process.
- 18. A composite obtained by melting together at least two organic UV filters according to claim 1.
- 19. A method according to claim 1, wherein an inorganic pigment is additionally mixed in.
- 20. A method according to claim 19, wherein the inorganic pigments are chosen from TiO2, ZnO, iron oxides, mica and Ti or zinc salts of organic acids.
- 21. A composite obtained by melting together at least two organic UV filters according to claim 1 and at least one inorganic pigment.
- 22. A method according to claim 1, wherein the mixture additionally comprises an antioxidant.
- 23. A method according to claim 22, wherein the antioxidant is selected from the group consisting of tocopherols, ellagic acid, propyl gallate, butylated hydroxytoluene, butylated hydroxyanisole, 2,4,6-tris(3,5-di-t-butyl-4-hydroxybenzyl)mesitylene, tetrakis[methylene-3-(3′,5′-di-t-butyl-4′-hydroxyphenyl)propionate]methane, the compound of the formula ferulic acid derivatives, rutic acid, rutic acid derivatives; urocanic acid, urocanic acid derivatives and propolis.
- 24. A composite obtained by melting together at least two organic UV filters according to claim 1 and at least one antioxidant, and, optionally, one or more inorganic pigments.
- 25. A method according to claim 1, wherein the mixture additionally comprises a cationic or anionic compound.
- 26. A method according to claim 25, wherein the cationic or anionic compound is chosen from camphorbenzalkonium methosulfates, fatty amines, betaines, quats, citric monoglyceride, sodium methylcocoyltaurate, phospholipids, ceramides and phytosterols.
- 27. A composite obtainable by melting together at least two organic UV filters according to claim 1 and at least one cationic or anionic compound.
- 28. A method according to claim 1, wherein the mixture additionally comprises a pharmaceutical or cosmetic active ingredient.
- 29. A cosmetic formulation comprising a mixture of organic UV filters according to claim 1, optionally one or more compounds selected from the group consisting of antioxidants, inorganic pigments and cationic or anionic compounds, and cosmetically compatible carriers or auxiliaries.
- 30. A cosmetic formulation according to claim 29, which additionally comprises an oil-soluble, nonmicronized UV filter.
- 31. A pharmaceutical formulation comprising a mixture of at least two organic UV filters according to claim 1, optionally one or more compounds selected from the group consisting of antioxidants, inorganic pigments and cationic or anionic compounds, and pharmaceutically compatible carriers or auxiliaries.
Priority Claims (1)
Number |
Date |
Country |
Kind |
1281/99 |
Jul 1999 |
CH |
|
Parent Case Info
This is a continuation of application Ser. No. 09/612,748, filed on Jul. 10, 2000.
US Referenced Citations (7)
Number |
Name |
Date |
Kind |
5869030 |
Dümler et al. |
Feb 1999 |
A |
5955060 |
Hüglin et al. |
Sep 1999 |
A |
5980872 |
Luther et al. |
Nov 1999 |
A |
6180090 |
Gers-Barlag et al. |
Jan 2001 |
B1 |
6217856 |
Ehlis et al. |
Apr 2001 |
B1 |
6221342 |
Hüglin et al. |
Apr 2001 |
B1 |
6235271 |
Luther et al. |
May 2001 |
B1 |
Foreign Referenced Citations (1)
Number |
Date |
Country |
2303549 |
Feb 1997 |
GB |
Continuations (1)
|
Number |
Date |
Country |
Parent |
09/612748 |
Jul 2000 |
US |
Child |
10/067027 |
|
US |