Claims
- 1. A pharmaceutical composition for treating inflammatory pain or migraine, comprising an effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient,
- 2. A phamarceutical according to claim 1, wherein in formula I
R1 represents methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, n-hexyl, n-octyl, 1,1,3,3-tetramethylbutyl; CH2-aryl, which is unsubstituted or mono- or poly-substituted; CH2CO2—C1-6-alkyl, wherein the alkyl is straight-chained or branched; CH2PO(O—C1-6-alkyl)2, wherein the alkyl is straight-chained or branched; CH2SiR2R13R14, CH2CH2-morpholin-4-yl; (CH2)n—NC, wherein n=2, 3, 4, 5 or 6; C3-8-cycloalkyl, wherein the cycloalkyl is unsubstituted or mono- or poly-substituted; or phenyl, wherein the phenyl is unsubstituted or mono- or poly-substituted, R2 represents H or C(═O)—C1-4-alkyl, R3 represents methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, cyclopropyl, cyclopentyl or cyclohexyl, which are unsubstituted or mono- or poly-substituted; phenyl, which is unsubstituted or mono- or poly-substituted; 1-naphthyl or 2-naphthyl, wherein the naphthyl is unsubstituted or mono- or poly-substituted; 9-phenanthrenyl, pyrrol-2-yl, pyrrol-3-yl, pyridin-2-yl, pyridin-3-yl or pyridin-4-yl, wherein the pyrrolyl or pyridinyl are unsubstituted or mono- or poly-substituted; furan-2-yl or furan-3-yl, wherein the furanyl is unsubstituted or mono- or poly-substituted; thien-2-yl or thien-3-yl, wherein the thienyl is unsubstituted or mono- or poly-substituted; imidazol-2-yl, imidazol-4-yl, imidazol-5-yl, wherein the imidazolyl is unsubstituted or mono- or poly-substituted; thiazol-2-yl, thiazol-4-yl, thiazol-5-yl, wherein the thiazolyl is unsubstituted or mono- or poly-substituted; oxazol-2-yl, oxazol-4-yl, oxazol-5-yl, wherein the oxazolyl is unsubstituted or mono- or poly-substituted; isooxazol-3-yl, isooxazol-4-yl, isooxazol-5-yl, wherein the isooxazolyl is unsubstituted or mono- or poly-substituted; indol-2-yl, benzofuran-2-yl or benzofuran-3-yl, R4, R5, R6 and R7 each independently of the others represents H, methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, CF3, F, Cl, Br, I, CO2H, CO2-methyl, CO2-ethyl, C(═O)CH3 or NO2, or R6 and R7 form the hydrocarbon bridge —CH═CH—CH═CH—, R8 represents C(═O)CH3 and R12, R13 and R14 each independently of the others represents C1-6-alkyl, which is straight-chained or branched and is unsubstituted or mono- or poly-substituted; C3-8-cycloalkyl or CH2—C3-8-cycloalkyl, wherein cycloalkyl is unsubstituted or mono- or poly-substituted; or phenyl, wherein phenyl is unsubstituted or mono- or poly-substituted.
- 3. A pharmaceutical composition according to claim 2, wherein in formula I
R1 represents methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, n-hexyl, n-octyl, 1,1,3,3-tetramethylbutyl; CH2-aryl, wherein the aryl is unsubstituted or mono- or poly-substituted; CH2CO2—C1-6-alkyl, wherein the alkyl is straight-chained or branched; CH2PO(O—C1-6-alkyl)2, wherein the alkyl is straight-chained or branched, CH2SiR2R13R4, CH2CH2-morpholin-4-yl; (CH2)n—NC, wherein n=2, 3, 4, 5 or 6; C3-8-cycloalkyl, wherein the cycloalkyl is unsubstituted or mono- or poly-substituted; or phenyl, which is unsubstituted or mono- or poly-substituted, R2 represents H or C(═O)—C1-4-alkyl, R3 represents methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, cyclopropyl, cyclopentyl or cyclohexyl, which, independently of one another, are unsubstituted or mono- or poly-substituted; phenyl, which is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy and dimethylamino; 1-naphthyl or 2-naphthyl, wherein the naphthyl is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy and dimethylamino; 9-phenanthrenyl, pyrrol-2-yl; pyridin-2-yl, pyridin-3-yl or pyridin-4-yl, wherein the pyridinyl is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy, dimethylamino, carboxy, carboxymethyl, carboxyethyl, hydroxymethyl, chlorophenyl, nitrophenyl, [1,3]-dioxolan and methylsulfanyl; furan-2-yl or furan-3-yl, wherein the furanyl is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy, dimethylamino, carboxy, carboxymethyl, carboxyethyl, hydroxymethyl, chlorophenyl, nitrophenyl, [1,3]-dioxolan and methylsulfanyl; thien-2-yl or thien-3-yl, wherein the thienyl is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy, dimethylamino, carboxy, carboxymethyl, carboxyethyl, hydroxymethyl, chlorophenyl, nitrophenyl, [1,3]-dioxolan and methylsulfanyl; indol-2-yl, benzofuran-2-yl or benzofuran-3-yl, R4, R5, R6 and R7 each independently of the others represents H, methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, CF3, F, Cl, Br, I, CO2H, CO2-methyl, CO2-ethyl, C(═O)CH3 or NO2, or R6 and R7 form the hydrocarbon bridge —CH═CH—CH═CH—, R8 represents C(═O)CH3 and R12, R13 and R14 each independently of the others represents C1-6-alkyl, which is straight-chained or branched, and unsubstituted or mono- or poly-substituted; C3-8-cycloalkyl or CH2—C3-8-cycloalkyl, wherein the cycloalkyl is unsubstituted or mono- or poly-substituted; or phenyl, wherein the phenyl is unsubstituted or mono- or poly-substituted.
- 4. A pharmaceutical composition according to claim 3, wherein in formula I
R1 represents methyl, n-butyl, 1,1,3,3-tetramethylbutyl, benzyl, 2-chlorobenzyl, 2-methoxybenzyl, CH2CO2CH3, (CH2)6—NC, cyclopentyl, cyclohexyl, phenyl, 2,6-dimethylphenyl, 3-chlorophenyl or 3-chloro-4-fluorophenyl, R2 represents H or C(═O)CH3, R3 represents methyl, tert-butyl, cyclohexyl, phenyl, 2-methylphenyl, 3-methylphenyl, 4-methylphenyl, 2-trifluoromethylphenyl, 3-trifluoromethylphenyl, 4-trifluoromethylphenyl, 2-hydroxyphenyl, 2-methoxyphenyl, 3-hydroxyphenyl, 3-methoxyphenyl, 2-fluorophenyl, 3-fluorophenyl, 4-fluorophenyl, 2-chlorophenyl, 3-chlorophenyl, 4-chlorophenyl, 2-bromophenyl, 3-bromophenyl, 4-bromophenyl, 2-nitrophenyl, 3-nitrophenyl, 4-nitrophenyl, 3-(4-chlorophenoxy)-phenyl, 2,4-dimethylphenyl, 2,3-dimethoxyphenyl, 3,4-dimethoxyphenyl, 3-methoxy-4-acetoxyphenyl, 2,3-dichlorophenyl, 2,4-dichlorophenyl, 2-chloro-4-fluorophenyl, 2-chloro-6-fluorophenyl, 4-bromo-2-fluorophenyl, 3,4,5-trimethoxyphenyl, 1-naphthyl, 2-ethoxy-naphth-1-yl, 4-dimethylamino-napth-1-yl, 9-phenanthrenyl, pyrrol-2-yl, N-methylpyrrol-2-yl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, furan-2-yl, furan-3-yl, 5-methyl-furan-2-yl, 4,5-dimethyl-furan-2-yl, 5-hydroxymethyl-furan-2-yl, 5-acetoxymethyl-furan-2-yl, 5-carboxy-furan-2-yl, 5-[1,3]-dioxolan-furan-2-yl, 3-bromo-furan-2-yl, 5-bromo-furan-2-yl, 5-nitro-furan-2-yl, 5-(2-nitrophenyl)-furan-2-yl, 5-(2-chlorophenyl)-furan-2-yl, 5-(3-chlorophenyl)-furan-2-yl, 5-(3-chlorophenyl)-furan-3-yl, 5-(4-chlorophenyl)-furan-2-yl, benzo[b]furan-2-yl, thien-2-yl, thien-3-yl, 5-methyl-thien-2-yl, 5-carboxy-thien-2-yl, 3-bromo-thien-2-yl, 5-chloro-thien-2-yl or 5-methylsulfanyl-thien-2-yl, R4 represents H, CH3, Cl, Br or CO2H, R5 represents H, CH3, C2H5 or Cl, R6 represents H, CH3, Cl, Br or NO2, R7 represents H, CH3 or n-C3H7 and R8 represents C(═O)CH3.
- 5. A pharmaceutical composition according to claim 4, wherein in formula I R4 and R6 represent H, R5 represents H, CH3 or C2H5 and R7 represents H or CH3.
- 6. A pharmaceutical composition according to claim 5, wherein the compound is selected from the group consisting of:
tert-butyl-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(5,7-dimethyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (5,7-dimethyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, {6-[5,7-dimethyl-2-(1H-pyrrol-2-yl)-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, tert-butyl-[2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-amine, [2-(3,4-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1, 1,3,3-tetramethyl-butyl)-amine, cyclohexyl-(7-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, (1,1,3,3-tetramethyl-butyl)-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(7-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(7-methyl-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, cyclohexyl-[7-methyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-amine, tert-butyl-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, (7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, cyclohexyl-(7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-yl)-amine, [2-(2-fluoro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, (2,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino)-acetic acid methyl ester, methylidyne-[6-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, 3-(3-tert-butylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-phenol, cyclohexyl-[2-(2-fluoro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, tert-butyl-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine, 3-(3-tert-butylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenol, tert-butyl-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, (7-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, butyl-(2-cyclohexyl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, 3-[5,7-dimethyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-phenol, (2,6-dimethyl-phenyl)-(5,7-dimethyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-amine, tert-butyl-(7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (2,6-dimethyl-phenyl)-[2-(2-fluoro-phenyl)-5,7-dimethyl-imidazo[1,2-a]-pyridin-3-yl]-amine, cyclohexyl-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, [5,7-dimethyl-2-(1H-pyrrol-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, butyl-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, (5,7-dimethyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, [2-(2,3-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, (2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, [2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, [2-(3-bromo-thiophen-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, (2,6-dimethyl-phenyl)-[2-(2-fluoro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, (2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, [6-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, (7-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, [2-(2,3-dichloro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethylphenyl)-amine, [2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, butyl-[2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-amine, methylidyne-[6-(7-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, tert-butyl-[5,7-dimethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-amine, acetic acid 5-(3-cyclohexylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-yl methyl ester, [2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, [2-(3,4-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, 3-(3-butylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenol, (2-benzofuran-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, (2-benzofuran-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(2,6-dimethylphenyl)-amine, acetic acid 5-(3-cyclohexylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-yl methyl ester, [6-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, butyl-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, {6-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, {5-[5,7-dimethyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-furan-2-yl}-methanol, (7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, [5-(3-tert-butylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-yl]-methanol, tert-butyl-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-amine, (2-benzofuran-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, 5-(3-tert-butylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-carboxylic acid, tert-butyl-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, [2-(2,3-dichlorophenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, (7-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, (2,6-dimethyl-phenyl)-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-amine, 3-(3-butylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-phenol, butyl-[2-(2,3-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, {6-[5,7-dimethyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, tert-butyl-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, [2-(2,3-dichlorophenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, (2,6-dimethyl-phenyl)-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]-pyridin-3-yl]-amine, {2-[5-(2-chlorophenyl)-furan-2-yl]-7-methyl-imidazo[1,2-a]pyridin-3-yl}-(1,1,3,3-tetramethyl-butyl)-amine, 5-[7-methyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-furan-2-carboxylic acid, cyclohexyl-[2-(2-methoxy-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, 3-[7-methyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-phenol, [2-(2,3-dichlorophenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, [2-(2,4-dichlorophenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, [2-(5-bromofuran-2-yl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, 5-(3-cyclohexylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-carboxylic acid, [6-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, [2-(2,4-dichlorophenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, (2-benzofuran-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-(2,6-dimethylphenyl)-amine, 5-(3-cyclohexylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-carboxylic acid, {6-[2-(2-bromophenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, tert-butyl-(2-cyclohexyl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, tert-butyl-(2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, (5,7-dimethyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, [2-(2,3-dichlorophenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethylphenyl)-amine, methylidyne-[6-(7-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, {2-[5-(3-chlorophenyl)-furan-2-yl]-7-methyl-imidazo[1,2-a]pyridin-3-yl}-(1,1,3,3-tetramethyl-butyl)-amine, cyclohexyl-[7-methyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-amine, [2-(2-bromophenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-cyclohexyl-amine, [2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, {5-[7-methyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-furan-2-yl}-methanol, (6-{2-[5-(2-chlorophenyl)-furan-2-yl]-5-methyl-imidazo[1,2-a]pyridin-3-ylamino}-hexyl)-methylidyne-ammonium, cyclohexyl-[5,7-dimethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-amine, cyclohexyl-[2-(4,5-dimethyl-furan-2-yl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, [6-(5,7-dimethyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, methylidyne-[6-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, [2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, {6-[2-(3,4-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, 5-(3-tert-butylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-thiophene-2-carboxylic acid, cyclohexyl-(8-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-amine, [2-(2,3-dichloro-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, 5-(3-butylamino-imidazo[1,2-a]pyrazin-2-yl)-thiophene-2-carboxylic acid, cyclohexyl-(5,7-dimethyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (2-benzofuran-2-yl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, {6-[2-(2-fluoro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, [2-(2,3-dimethoxy-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, methylidyne-[6-(7-methyl-2-phenanthren-9-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, 5-(3-tert-butylamino-imidazo[1,2-a]pyrazin-2-yl)-thiophene-2-carboxylic acid, tert-butyl-(8-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2-furan-2-yl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, methylidyne-[6-(7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, tert-butyl-(2-cyclohexyl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, (6-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, tert-butyl-(6-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyrimidin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, 5-(3-tert-butylamino-6-methyl-imidazo[1,2-a]pyridin-2-yl)-thiophene-2-carboxylic acid, [6-(5,7-dimethyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, 3-[3-(2,6-dimethyl-phenylamino)-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl]-phenol, (2,6-dimethyl-phenyl)-(8-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-amine, {6-[2-(3-hydroxy-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, {5-[3-(2,6-dimethyl-phenylamino)-7-methyl-imidazo[1,2-a]pyrimidin-2-yl]-furan-2-yl}-methanol, (8-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, [2-(2,4-dichlorophenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethylphenyl)-amine, butyl-[2-(2,4-dichloro-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, butyl-[2-(4-dimethylamino-naphthalen-1-yl)-imidazo[1,2-a]pyrazin-3-yl]-amine, {6-[2-(2-bromo-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, butyl-[2-(2-methoxy-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, (2-cyclohexyl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, cyclohexyl-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, (2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino)-acetic acid methyl ester, N-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-tert-butyl-N-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-(5,7-dimethyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-(5,7-dimethyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethylbutyl)-acetamide, N-(1,1,3,3-tetramethyl-butyl)-N-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-(7-methyl-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, 5-[3-(acetyl-tert-butyl-amino)-imidazo[1,2-a]pyrazin-2-yl]-thiophene-2-carboxylic acid, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-5,7-dimethyl-imidazo[1,2-a]-pyridin-2-yl}-furan-2-carboxylic acid, N-[2-(5-hydroxymethyl-furan-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(3-bromo-thiophen-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-tert-butyl-N-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, acetic acid 5-[3-(acetyl-cyclohexyl-amino)-5,7-dimethyl-imidazo[1,2-a]-pyridin-2-yl]-furan-2-yl methyl ester, {6-[acetyl-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-[2-(2,3-dichloro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-[2-(3-bromo-thiophen-2-yl)-imidazo[1,2-a]pyridin-3-yl]-N-cyclohexyl-acetamide, N-(5,7-dimethyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-cyclohexyl-N-(7-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-[7-methyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-(6,8-dibromo-2-furan-2-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(7-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl).—N-(1,1,3,3-tetramethyl-butyl)-acetamide, acetic acid 5-[3-(acetyl-cyclohexyl-amino)-7-methyl-imidazo[1,2-a]pyridin-2-yl]-furan-2-yl methyl ester, N-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(2,3-dichloro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-cyclohexyl-N-[5,7-dimethyl-2-(5-methyl-furan-2-yl)-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-butyl-N-[2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-cyclohexyl-N-[5,7-dimethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, [acetyl-(2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amino]-acetic acid methyl ester, N-cyclohexyl-N-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-imidazo[1,2-a]pyridin-2-yl}-thiophene-2-carboxylic acid, N-[2-(2,4-dichloro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-cyclohexyl-N-[7-methyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-(2-tert-butyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(2,6-dimethylphenyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-[2-(3-hydroxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(2-fluoro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, 5-[3-(acetyl-tert-butyl-amino)-5-methyl-imidazo[1,2-a]pyridin-2-yl]-thiophene-2-carboxylic acid, N-(2,6-dimethyl-phenyl)-N-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-(7-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethylbutyl)-acetamide, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-7-methyl-imidazo[1,2-a]-pyridin-2-yl}-furan-2-carboxylic acid, N-cyclohexyl-N-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2-benzofuran-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(2,6-dimethyl-phenyl)-acetamide, N-tert-butyl-N-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-[2-(2,3-dichloro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-{2-[3-(4-chloro-phenoxy)-phenyl]-imidazo[1,2-a]pyridin-3-yl}-N-(2,6-dimethyl-phenyl)-acetamide, N-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, 5-[3-(acetyl-cyclohexyl-amino)-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl]-furan-2-carboxylic acid, N-tert-butyl-N-[7-methyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(5-methyl-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, 5-[3-(acetyl-tert-butyl-amino)-7-methyl-imidazo[1,2-a]pyridin-2-yl]-furan-2-carboxylic acid, N-[2-(4,5-dimethyl-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-cyclohexyl-N-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-imidazo[1,2-a]pyrazin-2-yl}-thiophene-2-carboxylic acid, N-butyl-N-(2-o-tolyl-imidazo[1,2-a]pyrimidin-3-yl)acetamide, N-[2-(3,4-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-tert-butyl-N-(7-methyl-2-phenanthren-9-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(2-fluoro-phenyl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-[2-(2-methoxy-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(3-hydroxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-(2-tert-butyl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(2,6-dimethylphenyl)-acetamide, acetic acid 4-{3-[acetyl-(2,6-dimethyl-phenyl)-amino]-6-bromo-8-methyl-imidazo[1,2-a]pyridin-2-yl}-2-methoxy-phenyl ester, N-tert-butyl-N-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, [6-(acetyl-{7-methyl-2-[5-(2-nitro-phenyl)-furan-2-yl]-imidazo[1,2-a]pyridin-3-yl}-amino)-hexyl]-methylidyne-ammonium, N-(2-benzofuran-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2-benzofuran-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, 5-[3-(acetyl-tert-butyl-amino)-imidazo[1,2-a]pyridin-2-yl]-thiophene-2-carboxylic acid, N-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-tert-butyl-N-[2-(5-methyl-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-tert-butyl-N-[2-(5-methylsulfanyl-thiophen-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, N-[2-(4,5-dimethyl-furan-2-yl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-butyl-N-[2-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, N-[2-(3-bromo-thiophen-2-yl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-N-cyclohexyl-acetamide, 5-{3-[acetyl-(2,6-dimethyl-phenyl)-amino]-6-methyl-imidazo[1,2-a]pyridin-2-yl}-thiophene-2-carboxylic acid, N-butyl-N-[2-(2,3-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-tert-butyl-N-[2-(2,3-dichloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-(2-furan-2-yl-5-propyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethylbutyl)-acetamide, 5-[3-(acetyl-cyclohexyl-amino)-imidazo[1,2-a]pyridin-2-yl]-thiophene-2-carboxylic acid, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-8-methyl-imidazo[1,2-a]-pyridin-2-yl}-furan-2-carboxylic acid, 3-(acetyl-butyl-amino)-2-pyridin-2-yl-imidazo[1,2-a]pyridine-8-carboxylic acid, {6-[acetyl-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-tert-butyl-N-[2-(5-methylsulfanyl-thiophen-2-yl)-imidazo[1,2-a]pyrazin-3-yl]-acetamide, 5-[3-(acetyl-cyclohexyl-amino)-5-methyl-imidazo[1,2-a]pyridin-2-yl]-thiophene-2-carboxylic acid, N-[2-(5-methylsulfanyl-thiophen-2-yl)-imidazo[1,2-a]pyrazin-3-y]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(2,3-dichloro-phenyl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-butyl-N-[2-(2-methoxy-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, (6-{acetyl-[2-(2-methoxy-phenyl)-6-nitro-imidazo[1,2-a]pyridin-3-yl]-amino}-hexyl)-methylidyne-ammonium, N-(2-benzofuran-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(2,6-dimethylphenyl)-acetamide, (6-{acetyl-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-amino}-hexyl)-methylidyne-ammonium, {6-[acetyl-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethylbutyl)-acetamide, acetic acid 5-{3-[acetyl-(2,6-dimethyl-phenyl)-amino]-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl}-furan-2-yl methyl ester, {acetyl-[2-(3-hydroxy-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-amino}-acetic acid methyl ester, N-tert-butyl-N-[2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-butyl-N-[2-(2-chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-[2-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethylphenyl)-acetamide, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-7-methyl-imidazo[1,2-a]-pyrimidin-2-yl}-furan-2-carboxylic acid, acetic acid 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-imidazo[1,2-a]-pyrimidin-2-yl}-furan-2-yl methyl ester, N-(2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, acetic acid 4-[3-(acetyl-cyclohexyl-amino)-5-amino-7-chloro-imidazo[1,2-a]-pyrimidin-2-yl]-2-methoxy-phenyl ester, acetic acid 4-[3-(acetyl-cyclohexyl-amino)-5,7-dimethyl-imidazo[1,2-a]-pyrimidin-2-yl]-2-methoxy-phenyl ester, N-[6-bromo-2-(2-chloro-6-fluoro-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-N-cyclohexyl-acetamide, N-[2-(2-chloro-6-fluoro-phenyl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-N-cyclohexyl-acetamide, N-butyl-N-[2-(2,3-dichloro-phenyl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, N-[2-(5-chloro-thiophen-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, [acetyl-(2-cyclohexyl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amino]-acetic acid methyl ester, N-tert-butyl-N-[2-(2-chloro-6-fluoro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-cyclohexyl-N-(5,7-dimethyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, acetic acid 5-[3-(acetyl-cyclohexyl-amino)-5-methyl-imidazo[1,2-a]pyridin-2-yl]-furan-2-yl methyl ester, N-(2,6-dimethyl-phenyl)-N-[6-methyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-cyclohexyl-N-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-tert-butyl-N-(5-propyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-[2-(5-methyl-thiophen-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, 3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-2-furan-2-yl-imidazo[1,2-a]-pyridine-8-carboxylic acid, N-tert-butyl-N-[2-(4,5-dimethyl-furan-2-yl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-{2-[3-(4-chloro-phenoxy)-phenyl]-imidazo[1,2-a]pyridin-3-yl}-N-cyclohexyl-acetamide, acetic acid 4-[3-(acetyl-cyclohexyl-amino)-imidazo[1,2-a]pyrimidin-2-yl]-2-methoxy-phenyl ester, N-[2-(5-bromo-furan-2-yl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(3-hydroxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, N-cyclohexyl-N-[2-(2,3-dichloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-cyclohexyl-N-[2-(2,4-dichloro-phenyl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-cyclohexyl-N-[2-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, [acetyl-(2-o-tolyl-imidazo[1,2-a]pyrazin-3-yl)-amino]-acetic acid methyl ester, N-tert-butyl-N-(6,8-dichloro-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(5-propyl-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, {6-[acetyl-(7-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-butyl-N-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, (6-{acetyl-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amino}-hexyl)-methylidyne-ammonium, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-6-methyl-imidazo[1,2-a]pyridin-2-yl}-furan-2-carboxylic acid, N-butyl-N-[2-(3,4,5-trimethoxy-phenyl)-imidazo[1,2-a]pyrazin-3-yl]acetamide, N-butyl-N-[2-(3-hydroxy-phenyl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, [acetyl-(2-o-tolyl-imidazo[1,2-a]pyrimidin-3-yl)-amino]-acetic acid methyl ester, N-(2-benzofuran-2-yl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-butyl-N-(7-methyl-2-p-tolyl-imidazo[1,2-a]pyrimidin-3-yl)-acetamide, N-tert-butyl-N-(6,8-dibromo-2-methyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, {6-[acetyl-(5,7-dimethyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-tert-butyl-N-[2-(2-ethoxy-naphthalen-1-yl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-tert-butyl-N-[2-(2-chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, cyclohexyl-[7-methyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-amine hydrochloride, tert-butyl-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, tert-butyl-(7-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, cyclohexyl-(5,7-dimethyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, (2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine hydrochloride, tert-butyl-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, [2-(2-fluorophenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine hydrochloride, cyclohexyl-(7-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, (2-furan-2-yl-7-methyl-imidazo[1,2-a]pyrimidin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine hydrochloride, tert-butyl-[2-(4-nitro-phenyl)-imidazo[1,2-a]pyrazin-3-yl]-amine hydrochloride, N-{2-[3-(4-chlorophenoxy)-phenyl]-imidazo[1,2-a]pyridin-3-yl}-N-cyclohexyl-acetamide hydrochloride, N-cyclohexyl-N-(7-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetamide hydrochloride, N-(2,6-dimethyl-phenyl)-N-[2-(2,4-dimethyl-phenyl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide hydrochloride, 1-acetyl-3-(acetyl-cyclohexyl-amino)-7-methyl-2-o-tolyl-imidazo[1,2-a]-pyridin-1-ium) chloride hydrochloride, cyclohexyl-(2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, cyclopentyl-(2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, [2-(4-bromo-2-fluoro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]cyclopentyl-amine hydrochloride, cyclopentyl-{5,7-dimethyl-2-[5-(2-nitro-phenyl)-furan-2-yl]-imidazo[1,2-a]-pyridin-3-yl}-amine hydrochloride, {2-[5-(4-chlorophenyl)-furan-2-yl]-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl}-cyclopentyl-amine hydrochloride, cyclopentyl-(2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, (2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine hydrochloride, benzyl-(7-methyl-2-thiophen-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, cyclohexyl-(2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, (2-furan-3-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine hydrochloride, (5,7-dimethyl-2-thiophen-3-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine hydrochloride, [7-ethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(2-methoxybenzyl)-amine, (2-chlorobenzyl)-[7-ethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-amine, [7-ethyl-2-(5-methyl-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(2-methoxybenzyl)-amine, (2-chlorobenzyl)-(7-ethyl-2-furan-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (3-chloro-4-fluorophenyl)-[7-ethyl-2-(5-methyl-furan-2-yl)-imidazo[1,2-a]-pyridin-3-yl]-amine, (2-benzofuran-2-yl-7-ethyl-imidazo[1,2-a]pyridin-3-yl)-(3-chloro-4-fluorophenyl)-amine, (2-benzofuran-2-yl-7-ethyl-imidazo[1,2-a]pyridin-3-yl)-(3-chlorophenyl)-amine, (3-chloro-4-fluorophenyl)-{2-[5-(3-chloro-phenyl)-furan-2-yl]-7-ethyl-imidazo[1,2-a]pyridin-3-yl}-amine, (3-chloro-4-fluorophenyl)-{2-[5-(2-chlorophenyl)-furan-2-yl]-7-ethyl-imidazo[1,2-a]pyridin-3-yl}-amine, (3-chloro-4-fluorophenyl)-[2-(4,5-dimethyl-furan-2-yl)-7-ethyl-imidazo[1,2-a]pyridin-3-yl]-amine.
- 7. A pharmaceutical composition for treating one or more diseases selected from the group consisting of multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, cerebral ischaemia, diabetes, meningitis, and arteriosclerosis, or for healing wounds, the pharmaceutical composition comprising an effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient,
- 8. A phamarceutical according to claim 7, wherein in formula I
R1 represents methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, n-hexyl, n-octyl, 1, 1,3,3-tetramethylbutyl; CH2-aryl, which is unsubstituted or mono- or poly-substituted; CH2CO2—C1-6-alkyl, wherein the alkyl is straight-chained or branched; CH2PO(O—C1-6-alkyl)2, wherein the alkyl is straight-chained or branched; CH2SiR2R13R14, CH2CH2-morpholin-4-yl; (CH2)n—NC, wherein n=2, 3, 4, 5 or 6; C3-8-cycloalkyl, wherein the cycloalkyl is unsubstituted or mono- or poly-substituted; or phenyl, wherein the phenyl is unsubstituted or mono- or poly-substituted, R2 represents H or C(═O)—C1-4-alkyl, R3 represents methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, cyclopropyl, cyclopentyl or cyclohexyl, which are unsubstituted or mono- or poly-substituted; phenyl, which is unsubstituted or mono- or poly-substituted; 1-naphthyl or 2-naphthyl, wherein the naphthyl is unsubstituted or mono- or poly-substituted; 9-phenanthrenyl, pyrrol-2-yl, pyrrol-3-yl, pyridin-2-yl, pyridin-3-yl or pyridin-4-yl, wherein the pyrrolyl or pyridinyl are unsubstituted or mono- or poly-substituted; furan-2-yl or furan-3-yl, wherein the furanyl is unsubstituted or mono- or poly-substituted; thien-2-yl or thien-3-yl, wherein the thienyl is unsubstituted or mono- or poly-substituted; imidazol-2-yl, imidazol-4-yl, imidazol-5-yl, wherein the imidazolyl is unsubstituted or mono- or poly-substituted; thiazol-2-yl, thiazol-4-yl, thiazol-5-yl, wherein the thiazolyl is unsubstituted or mono- or poly-substituted; oxazol-2-yl, oxazol-4-yl, oxazol-5-yl, wherein the oxazolyl is unsubstituted or mono- or poly-substituted; isooxazol-3-yl, isooxazol-4-yl, isooxazol-5-yl, wherein the isooxazolyl is unsubstituted or mono- or poly-substituted; indol-2-yl, benzofuran-2-yl or benzofuran-3-yl, R4, R5, R6 and R7 each independently of the others represents H, methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, CF3, F, Cl, Br, I, CO2H, CO2-methyl, CO2-ethyl, C(═O)CH3 or NO2, or R6 and R7 form the hydrocarbon bridge —CH═CH—CH═CH—, R8 represents C(═O)CH3 and R12, R13 and R14 each independently of the others represents C1-6-alkyl, which is straight-chained or branched and is unsubstituted or mono- or poly-substituted; C3-8-cycloalkyl or CH2—C3-8-cycloalkyl, wherein cycloalkyl is unsubstituted or mono- or poly-substituted; or phenyl, wherein phenyl is unsubstituted or mono- or poly-substituted.
- 9. A pharmaceutical composition according to claim 8, wherein in formula I
R1 represents methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, n-hexyl, n-octyl, 1,1,3,3-tetramethylbutyl; CH2-aryl, wherein the aryl is unsubstituted or mono- or poly-substituted; CH2CO2—C1-6-alkyl, wherein the alkyl is straight-chained or branched; CH2PO(O—C1-6-alkyl)2, wherein the alkyl is straight-chained or branched, CH2SiR12R3R14, CH2CH2-morpholin-4-yl; (CH2)n—NC, wherein n=2, 3, 4, 5 or 6; C3-8-cycloalkyl, wherein the cycloalkyl is unsubstituted or mono- or poly-substituted; or phenyl, which is unsubstituted or mono- or poly-substituted, R2 represents H or C(═O)—C1-4-alkyl, R3 represents methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, cyclopropyl, cyclopentyl or cyclohexyl, which, independently of one another, are unsubstituted or mono- or poly-substituted; phenyl, which is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy and dimethylamino; 1-naphthyl or 2-naphthyl, wherein the naphthyl is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy and dimethylamino; 9-phenanthrenyl, pyrrol-2-yl; pyridin-2-yl, pyridin-3-yl or pyridin-4-yl, wherein the pyridinyl is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy, dimethylamino, carboxy, carboxymethyl, carboxyethyl, hydroxymethyl, chlorophenyl, nitrophenyl, [1,3]-dioxolan and methylsulfanyl; furan-2-yl or furan-3-yl, wherein the furanyl is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy, dimethylamino, carboxy, carboxymethyl, carboxyethyl, hydroxymethyl, chlorophenyl, nitrophenyl, [1,3]-dioxolan and methylsulfanyl; thien-2-yl or thien-3-yl, wherein the thienyl is unsubstituted or monosubstituted or poly-substituted by identical or different substituents selected from the group consisting of methyl, ethyl, n-propyl, prop-2-yl, n-butyl, sec-butyl, tert-butyl, isobutyl, CF3, OH, O-methyl, O-ethyl, F, Cl, Br, I, CN, NO2, 4-chlorophenoxy, acetoxy, dimethylamino, carboxy, carboxymethyl, carboxyethyl, hydroxymethyl, chlorophenyl, nitrophenyl, [1,3]-dioxolan and methylsulfanyl; indol-2-yl, benzofuran-2-yl or benzofuran-3-yl, R4, R5, R6 and R7 each independently of the others represents H, methyl, ethyl, n-propyl, 2-propyl, n-butyl, tert-butyl, CF3, F, Cl, Br, I, CO2H, CO2-methyl, CO2-ethyl, C(═O)CH3 or NO2, or R6 and R7 form the hydrocarbon bridge —CH═CH—CH═CH—, R8 represents C(═O)CH3 and R12, R13 and R14 each independently of the others represents C1-6-alkyl, which is straight-chained or branched, and unsubstituted or mono- or poly-substituted; C3-8-cycloalkyl or CH2—C3-8-cycloalkyl, wherein the cycloalkyl is unsubstituted or mono- or poly-substituted; or phenyl, wherein the phenyl is unsubstituted or mono- or poly-substituted.
- 10. A pharmaceutical composition according to claim 9, wherein in formula I
R1 represents methyl, n-butyl, 1,1,3,3-tetramethylbutyl, benzyl, 2-chlorobenzyl, 2-methoxybenzyl, CH2CO2CH3, (CH2)6—NC, cyclopentyl, cyclohexyl, phenyl, 2,6-dimethylphenyl, 3-chlorophenyl or 3-chloro-4-fluorophenyl, R2 represents H or C(═O)CH3, R3 represents methyl, tert-butyl, cyclohexyl, phenyl, 2-methylphenyl, 3-methylphenyl, 4-methylphenyl, 2-trifluoromethylphenyl, 3-trifluoromethylphenyl, 4-trifluoromethylphenyl, 2-hydroxyphenyl, 2-methoxyphenyl, 3-hydroxyphenyl, 3-methoxyphenyl, 2-fluorophenyl, 3-fluorophenyl, 4-fluorophenyl, 2-chlorophenyl, 3-chlorophenyl, 4-chlorophenyl, 2-bromophenyl, 3-bromophenyl, 4-bromophenyl, 2-nitrophenyl, 3-nitrophenyl, 4-nitrophenyl, 3-(4-chlorophenoxy)-phenyl, 2,4-dimethylphenyl, 2,3-dimethoxyphenyl, 3,4-dimethoxyphenyl, 3-methoxy-4-acetoxyphenyl, 2,3-dichlorophenyl, 2,4-dichlorophenyl, 2-chloro-4-fluorophenyl, 2-chloro-6-fluorophenyl, 4-bromo-2-fluorophenyl, 3,4,5-trimethoxyphenyl, 1-naphthyl, 2-ethoxy-naphth-1-yl, 4-dimethylamino-napth-1-yl, 9-phenanthrenyl, pyrrol-2-yl, N-methylpyrrol-2-yl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, furan-2-yl, furan-3-yl, 5-methyl-furan-2-yl, 4,5-dimethyl-furan-2-yl, 5-hydroxymethyl-furan-2-yl, 5-acetoxymethyl-furan-2-yl, 5-carboxy-furan-2-yl, 5-[1,3]-dioxolan-furan-2-yl, 3-bromo-furan-2-yl, 5-bromo-furan-2-yl, 5-nitro-furan-2-yl, 5-(2-nitrophenyl)-furan-2-yl, 5-(2-chlorophenyl)-furan-2-yl, 5-(3-chlorophenyl)-furan-2-yl, 5-(3-chlorophenyl)-furan-3-yl, 5-(4-chlorophenyl)-furan-2-yl, benzo[b]furan-2-yl, thien-2-yl, thien-3-yl, 5-methyl-thien-2-yl, 5-carboxy-thien-2-yl, 3-bromo-thien-2-yl, 5-chloro-thien-2-yl or 5-methylsulfanyl-thien-2-yl, R4 represents H, CH3, Cl, Br or CO2H, R5 represents H, CH3, C2H5 or Cl, R6 represents H, CH3, Cl, Br or NO2, R7 represents H, CH3 or n-C3H7 and R8 represents C(═O)CH3.
- 11. A pharmaceutical composition according to claim 10, wherein in formula I R4 and R6 represent H, R5 represents H, CH3 or C2H5 and R7 represents H or CH3.
- 12. A pharmaceutical composition according to claim 11, wherein the compound is selected from the group consisting of:
tert-butyl-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(5,7-dimethyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (5,7-dimethyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, {6-[5,7-dimethyl-2-(1H-pyrrol-2-yl)-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, tert-butyl-[2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-amine, [2-(3,4-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, cyclohexyl-(7-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, (1,1,3,3-tetramethyl-butyl)-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(7-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(7-methyl-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, cyclohexyl-[7-methyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-amine, tert-butyl-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, (7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, cyclohexyl-(7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-yl)-amine, [2-(2-fluoro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, (2,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino)-acetic acid methyl ester, methylidyne-[6-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, 3-(3-tert-butylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-phenol, cyclohexyl-[2-(2-fluoro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, tert-butyl-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine, 3-(3-tert-butylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenol, tert-butyl-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, (7-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, butyl-(2-cyclohexyl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, 3-[5,7-dimethyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-phenol, (2,6-dimethyl-phenyl)-(5,7-dimethyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-amine, tert-butyl-(7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (2,6-dimethyl-phenyl)-[2-(2-fluoro-phenyl)-5,7-dimethyl-imidazo[1,2-a]-pyridin-3-yl]-amine, cyclohexyl-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, [5,7-dimethyl-2-(1H-pyrrol-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, butyl-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, (5,7-dimethyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, [2-(2,3-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, (2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, [2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, [2-(3-bromo-thiophen-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, (2,6-dimethyl-phenyl)-[2-(2-fluoro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, (2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, [6-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, (7-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, [2-(2,3-dichloro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethylphenyl)-amine, [2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, butyl-[2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-amine, methylidyne-[6-(7-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, tert-butyl-[5,7-dimethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-amine, acetic acid 5-(3-cyclohexylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-yl methyl ester, [2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, [2-(3,4-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, 3-(3-butylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenol, (2-benzofuran-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, (2-benzofuran-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(2,6-dimethylphenyl)-amine, acetic acid 5-(3-cyclohexylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-yl methyl ester, [6-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, butyl-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, {6-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, {5-[5,7-dimethyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-furan-2-yl}-methanol, (7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, [5-(3-tert-butylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-yl]-methanol, tert-butyl-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-amine, (2-benzofuran-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, 5-(3-tert-butylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-carboxylic acid, tert-butyl-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, [2-(2,3-dichlorophenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, (7-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, (2,6-dimethyl-phenyl)-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-amine, 3-(3-butylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-phenol, butyl-[2-(2,3-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, {6-[5,7-dimethyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, tert-butyl-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, [2-(2,3-dichlorophenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethyl-phenyl)-amine, (2,6-dimethyl-phenyl)-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]-pyridin-3-yl]-amine, {2-[5-(2-chlorophenyl)-furan-2-yl]-7-methyl-imidazo[1,2-a]pyridin-3-yl}-(1,1,3,3-tetramethyl-butyl)-amine, 5-[7-methyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-furan-2-carboxylic acid, cyclohexyl-[2-(2-methoxy-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, 3-[7-methyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-phenol, [2-(2,3-dichlorophenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, [2-(2,4-dichlorophenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, [2-(5-bromofuran-2-yl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, 5-(3-cyclohexylamino-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-carboxylic acid, [6-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, [2-(2,4-dichlorophenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, (2-benzofuran-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-(2,6-dimethylphenyl)-amine, 5-(3-cyclohexylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-furan-2-carboxylic acid, {6-[2-(2-bromophenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, tert-butyl-(2-cyclohexyl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, tert-butyl-(2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine, (5,7-dimethyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, [2-(2,3-dichlorophenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethylphenyl)-amine, methylidyne-[6-(7-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, {2-[5-(3-chlorophenyl)-furan-2-yl]-7-methyl-imidazo[1,2-a]pyridin-3-yl}-(1,1,3,3-tetramethyl-butyl)-amine, cyclohexyl-[7-methyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-amine, [2-(2-bromophenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-cyclohexyl-amine, [2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, {5-[7-methyl-3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-furan-2-yl}-methanol, (6-{2-[5-(2-chlorophenyl)-furan-2-yl]-5-methyl-imidazo[1,2-a]pyridin-3-ylamino}-hexyl)-methylidyne-ammonium, cyclohexyl-[5,7-dimethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-amine, cyclohexyl-[2-(4,5-dimethyl-furan-2-yl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, [6-(5,7-dimethyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, methylidyne-[6-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, [2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, {6-[2-(3,4-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, 5-(3-tert-butylamino-7-methyl-imidazo[1,2-a]pyridin-2-yl)-thiophene-2-carboxylic acid, cyclohexyl-(8-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-amine, [2-(2,3-dichloro-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, 5-(3-butylamino-imidazo[1,2-a]pyrazin-2-yl)-thiophene-2-carboxylic acid, cyclohexyl-(5,7-dimethyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (2-benzofuran-2-yl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, {6-[2-(2-fluoro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, [2-(2,3-dimethoxy-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine, methylidyne-[6-(7-methyl-2-phenanthren-9-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, 5-(3-tert-butylamino-imidazo[1,2-a]pyrazin-2-yl)-thiophene-2-carboxylic acid, tert-butyl-(8-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2-furan-2-yl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, methylidyne-[6-(7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-ammonium, tert-butyl-(2-cyclohexyl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, (6-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, tert-butyl-(6-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyrimidin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, 5-(3-tert-butylamino-6-methyl-imidazo[1,2-a]pyridin-2-yl)-thiophene-2-carboxylic acid, [6-(5,7-dimethyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-ylamino)-hexyl]-methylidyne-ammonium, 3-[3-(2,6-dimethyl-phenylamino)-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl]-phenol, (2,6-dimethyl-phenyl)-(8-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-amine, {6-[2-(3-hydroxy-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, {5-[3-(2,6-dimethyl-phenylamino)-7-methyl-imidazo[1,2-a]pyrimidin-2-yl]-furan-2-yl}-methanol, (8-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine, [2-(2,4-dichlorophenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-(2,6-dimethylphenyl)-amine, butyl-[2-(2,4-dichloro-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, butyl-[2-(4-dimethylamino-naphthalen-1-yl)-imidazo[1,2-a]pyrazin-3-yl]-amine, {6-[2-(2-bromo-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-ylamino]-hexyl}-methylidyne-ammonium, butyl-[2-(2-methoxy-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-amine, (2-cyclohexyl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine, cyclohexyl-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, cyclohexyl-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine, (2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-ylamino)-acetic acid methyl ester, N-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-tert-butyl-N-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-(5,7-dimethyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-(5,7-dimethyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethylbutyl)-acetamide, N-(1,1,3,3-tetramethyl-butyl)-N-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-(7-methyl-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, 5-[3-(acetyl-tert-butyl-amino)-imidazo[1,2-a]pyrazin-2-yl]-thiophene-2-carboxylic acid, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-5,7-dimethyl-imidazo[1,2-a]-pyridin-2-yl}-furan-2-carboxylic acid, N-[2-(5-hydroxymethyl-furan-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(3-bromo-thiophen-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-tert-butyl-N-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, acetic acid 5-[3-(acetyl-cyclohexyl-amino)-5,7-dimethyl-imidazo[1,2-a]-pyridin-2-yl]-furan-2-yl methyl ester, {6-[acetyl-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-[2-(2,3-dichloro-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-[2-(3-bromo-thiophen-2-yl)-imidazo[1,2-a]pyridin-3-yl]-N-cyclohexyl-acetamide, N-(5,7-dimethyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-cyclohexyl-N-(7-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)acetamide, N-cyclohexyl-N-[7-methyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-(6,8-dibromo-2-furan-2-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(7-methyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, acetic acid 5-[3-(acetyl-cyclohexyl-amino)-7-methyl-imidazo[1,2-a]pyridin-2-yl]-furan-2-yl methyl ester, N-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(2,3-dichloro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-cyclohexyl-N-[5,7-dimethyl-2-(5-methyl-furan-2-yl)-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-butyl-N-[2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-cyclohexyl-N-[5,7-dimethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, [acetyl-(2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amino]-acetic acid methyl ester, N-cyclohexyl-N-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-imidazo[1,2-a]pyridin-2-yl}-thiophene-2-carboxylic acid, N-[2-(2,4-dichloro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-cyclohexyl-N-[7-methyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-(2-tert-butyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(2,6-dimethylphenyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-[2-(3-hydroxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(2-fluoro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, 5-[3-(acetyl-tert-butyl-amino)-5-methyl-imidazo[1,2-a]pyridin-2-yl]-thiophene-2-carboxylic acid, N-(2,6-dimethyl-phenyl)-N-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-(7-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethylbutyl)-acetamide, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-7-methyl-imidazo[1,2-a]-pyridin-2-yl}-furan-2-carboxylic acid, N-cyclohexyl-N-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2-benzofuran-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(2,6-dimethyl-phenyl)-acetamide, N-tert-butyl-N-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-[2-(2,3-dichloro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(2,3-dimethoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-{2-[3-(4-chloro-phenoxy)-phenyl]-imidazo[1,2-a]pyridin-3-yl}-N-(2,6-dimethyl-phenyl)-acetamide, N-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, 5-[3-(acetyl-cyclohexyl-amino)-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl]-furan-2-carboxylic acid, N-tert-butyl-N-[7-methyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(5-methyl-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, 5-[3-(acetyl-tert-butyl-amino)-7-methyl-imidazo[1,2-a]pyridin-2-yl]-furan-2-carboxylic acid, N-[2-(4,5-dimethyl-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-cyclohexyl-N-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(7-methyl-2-naphthalen-1-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-imidazo[1,2-a]pyrazin-2-yl}-thiophene-2-carboxylic acid, N-butyl-N-(2-o-tolyl-imidazo[1,2-a]pyrimidin-3-yl)acetamide, N-[2-(3,4-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-tert-butyl-N-(7-methyl-2-phenanthren-9-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(2-fluoro-phenyl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-[2-(2-methoxy-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(3-hydroxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-(2-tert-butyl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(2,6-dimethylphenyl)-acetamide, acetic acid 4-{3-[acetyl-(2,6-dimethyl-phenyl)-amino]-6-bromo-8-methyl-imidazo[1,2-a]pyridin-2-yl}-2-methoxy-phenyl ester, N-tert-butyl-N-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, [6-(acetyl-{7-methyl-2-[5-(2-nitro-phenyl)-furan-2-yl]-imidazo[1,2-a]pyridin-3-yl }-amino)-hexyl]-methylidyne-ammonium, N-(2-benzofuran-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2-benzofuran-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, 5-[3-(acetyl-tert-butyl-amino)-imidazo[1,2-a]pyridin-2-yl]-thiophene-2-carboxylic acid, N-(2-cyclohexyl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-tert-butyl-N-[2-(5-methyl-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-tert-butyl-N-[2-(5-methylsulfanyl-thiophen-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, N-[2-(4,5-dimethyl-furan-2-yl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-butyl-N-[2-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, N-[2-(3-bromo-thiophen-2-yl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-N-cyclohexyl-acetamide, 5-{3-[acetyl-(2,6-dimethyl-phenyl)-amino]-6-methyl-imidazo[1,2-a]pyridin-2-yl}-thiophene-2-carboxylic acid, N-butyl-N-[2-(2,3-dimethoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-tert-butyl-N-[2-(2,3-dichloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-(2-furan-2-yl-5-propyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethylbutyl)-acetamide, 5-[3-(acetyl-cyclohexyl-amino)-imidazo[1,2-a]pyridin-2-yl]-thiophene-2-carboxylic acid, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-8-methyl-imidazo[1,2-a]-pyridin-2-yl}-furan-2-carboxylic acid, 3-(acetyl-butyl-amino)-2-pyridin-2-yl-imidazo[1,2-a]pyridine-8-carboxylic acid, {6-[acetyl-(5,7-dimethyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-tert-butyl-N-[2-(5-methylsulfanyl-thiophen-2-yl)-imidazo[1,2-a]pyrazin-3-yl]-acetamide, 5-[3-(acetyl-cyclohexyl-amino)-5-methyl-imidazo[1,2-a]pyridin-2-yl]-thiophene-2-carboxylic acid, N-[2-(5-methylsulfanyl-thiophen-2-yl)-imidazo[1,2-a]pyrazin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-[2-(2,3-dichloro-phenyl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethyl-phenyl)-acetamide, N-butyl-N-[2-(2-methoxy-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, (6-{acetyl-[2-(2-methoxy-phenyl)-6-nitro-imidazo[1,2-a]pyridin-3-yl]-amino}-hexyl)-methylidyne-ammonium, N-(2-benzofuran-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(2,6-dimethylphenyl)-acetamide, (6-{acetyl-[2-(2-methoxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-amino}-hexyl)-methylidyne-ammonium, {6-[acetyl-(7-methyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethylbutyl)-acetamide, acetic acid 5-{3-[acetyl-(2,6-dimethyl-phenyl)-amino]-5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl}-furan-2-yl methyl ester, {acetyl-[2-(3-hydroxy-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-amino}-acetic acid methyl ester, N-tert-butyl-N-[2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-butyl-N-[2-(2-chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-[2-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-N-(2,6-dimethylphenyl)-acetamide, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-7-methyl-imidazo[1,2-a]-pyrimidin-2-yl}-furan-2-carboxylic acid, acetic acid 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-imidazo[1,2-a]-pyrimidin-2-yl}-furan-2-yl methyl ester, N-(2,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, acetic acid 4-[3-(acetyl-cyclohexyl-amino)-5-amino-7-chloro-imidazo[1,2-a]-pyrimidin-2-yl]-2-methoxy-phenyl ester, acetic acid 4-[3-(acetyl-cyclohexyl-amino)-5,7-dimethyl-imidazo[1,2-a]-pyrimidin-2-yl]-2-methoxy-phenyl ester, N-[6-bromo-2-(2-chloro-6-fluoro-phenyl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-N-cyclohexyl-acetamide, N-[2-(2-chloro-6-fluoro-phenyl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-N-cyclohexyl-acetamide, N-butyl-N-[2-(2,3-dichloro-phenyl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, N-[2-(5-chloro-thiophen-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, [acetyl-(2-cyclohexyl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-amino]-acetic acid methyl ester, N-tert-butyl-N-[2-(2-chloro-6-fluoro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-cyclohexyl-N-(5,7-dimethyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, acetic acid 5-[3-(acetyl-cyclohexyl-amino)-5-methyl-imidazo[1,2-a]pyridin-2-yl]-furan-2-yl methyl ester, N-(2,6-dimethyl-phenyl)-N-[6-methyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-cyclohexyl-N-(2-furan-2-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-(7-methyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-cyclohexyl-N-[2-(5-[1,3]dioxolan-2-yl-furan-2-yl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-tert-butyl-N-(5-propyl-2-pyridin-3-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-[2-(5-methyl-thiophen-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, 3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-2-furan-2-yl-imidazo[1,2-a]-pyridine-8-carboxylic acid, N-tert-butyl-N-[2-(4,5-dimethyl-furan-2-yl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-{2-[3-(4-chloro-phenoxy)-phenyl]-imidazo[1,2-a]pyridin-3-yl}-N-cyclohexyl-acetamide, acetic acid 4-[3-(acetyl-cyclohexyl-amino)-imidazo[1,2-a]pyrimidin-2-yl]-2-methoxy-phenyl ester, N-[2-(5-bromo-furan-2-yl)-8-methyl-imidazo[1,2-a]pyridin-3-yl]-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-(2,6-dimethyl-phenyl)-N-[2-(3-hydroxy-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, N-cyclohexyl-N-[2-(2,3-dichloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-cyclohexyl-N-[2-(2,4-dichloro-phenyl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide, N-cyclohexyl-N-[2-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, [acetyl-(2-o-tolyl-imidazo[1,2-a]pyrazin-3-yl)-amino]-acetic acid methyl ester, N-tert-butyl-N-(6,8-dichloro-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, N-tert-butyl-N-(5-propyl-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide, {6-[acetyl-(7-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-butyl-N-(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, (6-{acetyl-[2-(2-methoxy-phenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-amino}-hexyl)-methylidyne-ammonium, 5-{3-[acetyl-(1,1,3,3-tetramethyl-butyl)-amino]-6-methyl-imidazo[1,2-a]-pyridin-2-yl}-furan-2-carboxylic acid, N-butyl-N-[2-(3,4,5-trimethoxy-phenyl)-imidazo[1,2-a]pyrazin-3-yl]-acetamide, N-butyl-N-[2-(3-hydroxy-phenyl)-imidazo[1,2-a]pyrimidin-3-yl]-acetamide, [acetyl-(2-o-tolyl-imidazo[1,2-a]pyrimidin-3-yl)-amino]-acetic acid methyl ester, N-(2-benzofuran-2-yl-8-methyl-imidazo[1,2-a]pyridin-3-yl)-N-(1,1,3,3-tetramethyl-butyl)-acetamide, N-butyl-N-(7-methyl-2-p-tolyl-imidazo[1,2-a]pyrimidin-3-yl)-acetamide, N-tert-butyl-N-(6,8-dibromo-2-methyl-imidazo[1,2-a]pyridin-3-yl)-acetamide, {6-[acetyl-(5,7-dimethyl-2-pyridin-2-yl-imidazo[1,2-a]pyridin-3-yl)-amino]-hexyl}-methylidyne-ammonium, N-tert-butyl-N-[2-(2-ethoxy-naphthalen-1-yl)-7-methyl-imidazo[1,2-a]-pyridin-3-yl]-acetamide, N-tert-butyl-N-[2-(2-chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide, cyclohexyl-[7-methyl-2-(2-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-amine hydrochloride, tert-butyl-(2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, tert-butyl-(7-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, cyclohexyl-(5,7-dimethyl-2-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, (2-furan-2-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine hydrochloride, tert-butyl-(2,5,7-trimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, [2-(2-fluorophenyl)-7-methyl-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine hydrochloride, cyclohexyl-(7-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, (2-furan-2-yl-7-methyl-imidazo[1,2-a]pyrimidin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine hydrochloride, tert-butyl-[2-(4-nitro-phenyl)-imidazo[1,2-a]pyrazin-3-yl]-amine hydrochloride, N-{2-[3-(4-chlorophenoxy)-phenyl]-imidazo[1,2-a]pyridin-3-yl}-N-cyclohexyl-acetamide hydrochloride, N-cyclohexyl-N-(7-methyl-2-o-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetamide hydrochloride, N-(2,6-dimethyl-phenyl)-N-[2-(2,4-dimethyl-phenyl)-5-methyl-imidazo[1,2-a]pyridin-3-yl]-acetamide hydrochloride, 1-acetyl-3-(acetyl-cyclohexyl-amino)-7-methyl-2-o-tolyl-imidazo[1,2-a]-pyridin-1-ium) chloride hydrochloride, cyclohexyl-(2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, cyclopentyl-(2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, [2-(4-bromo-2-fluoro-phenyl)-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl]-cyclopentyl-amine hydrochloride, cyclopentyl-{5,7-dimethyl-2-[5-(2-nitro-phenyl)-furan-2-yl]-imidazo[1,2-a]-pyridin-3-yl}-amine hydrochloride, {2-[5-(4-chlorophenyl)-furan-2-yl]-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl}-cyclopentyl-amine hydrochloride, cyclopentyl-(2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, (2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-(11,1,3,3-tetramethylbutyl)-amine hydrochloride, benzyl-(7-methyl-2-thiophen-3-yl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, cyclohexyl-(2-furan-3-yl-5,7-dimethyl-imidazo[1,2-a]pyridin-3-yl)-amine hydrochloride, (2-furan-3-yl-7-methyl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine hydrochloride, (5,7-dimethyl-2-thiophen-3-yl-imidazo[1,2-a]pyridin-3-yl)-(1,1,3,3-tetramethyl-butyl)-amine hydrochloride, [7-ethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(2-methoxybenzyl)-amine, (2-chlorobenzyl)-[7-ethyl-2-(5-nitro-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-amine, [7-ethyl-2-(5-methyl-furan-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(2-methoxybenzyl)-amine, (2-chlorobenzyl)-(7-ethyl-2-furan-2-yl-imidazo[1,2-a]pyridin-3-yl)-amine, (3-chloro-4-fluorophenyl)-[7-ethyl-2-(5-methyl-furan-2-yl)-imidazo[1,2-a]-pyridin-3-yl]-amine, (2-benzofuran-2-yl-7-ethyl-imidazo[1,2-a]pyridin-3-yl)-(3-chloro-4-fluorophenyl)-amine, (2-benzofuran-2-yl-7-ethyl-imidazo[1,2-a]pyridin-3-yl)-(3-chlorophenyl)-amine, (3-chloro-4-fluorophenyl)-{2-[5-(3-chloro-phenyl)-furan-2-yl]-7-ethyl-imidazo[1,2-a]pyridin-3-yl}-amine, (3-chloro-4-fluorophenyl)-{2-[5-(2-chlorophenyl)-furan-2-yl]-7-ethyl-imidazo[1,2-a]pyridin-3-yl}-amine, (3-chloro-4-fluorophenyl)-[2-(4,5-dimethyl-furan-2-yl)-7-ethyl-imidazo[1,2-a]pyridin-3-yl]-amine.
- 13. A method for treating inflammatory pain, or migraine, or both, comprising administering an effective amount of a pharmaceutical composition according to claim 1 to a patient in need thereof.
- 14. A method according to claim 13, wherein the patient is human.
- 15. A method for treating inflammatory pain, or migraine, or both, comprising administering an effective amount of a pharmaceutical composition according to claim 6 to a patient in need thereof.
- 16. A method for treating one or more diseases selected from the group consisting of multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, cerebral ischaemia, diabetes, meningitis, and arteriosclerosis, or a method for healing wounds comprising administering an effective amount of a pharmaceutical composition according to claim 7 to a patient in need thereof.
- 17. A method according to claim 15, wherein the patient is human.
- 18. A method for treating one or more diseases selected from the group consisting of multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, cerebral ischaemia, diabetes, meningitis, and arteriosclerosis, or a method for healing wounds, comprising administering an effective amount of a pharmaceutical composition according to claim 12 to a patient in need thereof.
Priority Claims (1)
Number |
Date |
Country |
Kind |
100 50 663.1 |
Oct 2000 |
DE |
|
CROSS REFERENCE TO RELATED APPLICATIONS
[0001] The present application is a continuation of International Patent Application No. PCT/EP01/11701, filed Oct. 10, 2001, designating the United States of America and published in German as WO 02/30428 A1, the entire disclosure of which is incorporated herein by reference. Priority is claimed based on Federal Republic of Germany Patent Application No. 100 50 663.1, filed Oct. 13, 2000.
Continuations (1)
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Number |
Date |
Country |
Parent |
PCT/EP01/11701 |
Oct 2001 |
US |
Child |
10411402 |
Apr 2003 |
US |