The present invention is generally related to medical treatments, and more particularly to interstitial Brachytherapy. Malignant tumors are often treated by surgical resection to remove as much of the tumor as possible. Radiation therapy can then be used to target the residual tumor margin. The radiation therapy can be administered through various methods including external-beam radiation, stereotactic radiosurgery, and permanent or temporary brachytherapy.
Brachytherapy is a radiation therapy in which a source of therapeutic rays is inserted into the body at or near a tumor or other proliferative tissue disease site. At least one breast brachytherapy radiation treatment begins with insertion of a cavity evaluation device into the resected cavity during the lumpectomy procedure. If it is later determined that the patient is to be given brachytherapy treatment then the cavity evaluation device is removed during an office visit and a brachytherapy catheter is inserted into the path through the tissue previously occupied by the cavity evaluation device. More particularly, the catheter shaft is inserted into the tissue so that a balloon disposed at the distal end of the shaft is positioned within the resected cavity. The balloon is then inflated and radioactive material is loaded into one or more lumens for delivery via the brachytherapy catheter. The brachytherapy catheter is removed upon completion of the treatment.
The present invention is predicated in-part on recognition that introducing a device such as a brachytherapy catheter into a path previously occupied by a device such as a cavity evaluation device can be difficult to perform as an out-patient procedure. Because the path is through soft tissue it can close rapidly and does not always accurately guide the brachytherapy catheter to the resected cavity.
In accordance with an aspect of the invention, a method for facilitating brachytherapy treatment comprises the steps of: positioning a first device such that a distal end of the first device is disposed in a resected cavity of the patient, the first device including a shaft in which is disposed an elongated guide member; removing the first device from the resected cavity without removing the elongated guide member such that position of a portion of the elongated guide member in the resected cavity is maintained relative to the resected cavity; and introducing a brachytherapy catheter by introducing the elongated guide member into an opening of the brachytherapy catheter and using the elongated guide member to guide the brachytherapy catheter to the resected cavity.
In accordance with another aspect of the invention, apparatus for facilitating brachytherapy treatment comprises: a shaft; a tip disposed at a first end of the shaft; an inflatable member disposed around the shaft; an inflation lumen which transfers fluid into and out of the inflatable member; and an opening in the tip which receives a separate elongated guide member, and via which the guide member can be introduced to soft tissue.
In accordance with another aspect of the invention, apparatus for facilitating brachytherapy treatment comprises: a shaft; a tip disposed at a first end of the shaft; an inflatable member disposed around the shaft; an inflation lumen which transfers fluid into and out of the inflatable member; at least one dosing lumen; and an opening in the tip which receives a separate elongated guide member, and through which the guide member slidably moves in order to guide the apparatus through soft tissue.
One advantage of the guide member is that it helps to guide the brachytherapy catheter to the resected cavity. Furthermore, the guide member helps to accurately position the brachytherapy catheter and associated dosing lumens within the resected cavity.
Referring to
Referring now to
If it is later determined that the patient is to be given brachytherapy treatment then the device 100 is removed during an office visit and a brachytherapy catheter 600 with an inflatable member 602, such as a balloon, mounted on its distal end is inserted into the track through the tissue previously occupied by the cavity evaluation device 100. More particularly, the inflatable member 106 is deflated and the cavity evaluation device 100 is removed while the position of the guide member 102 relative to the resected cavity is maintained. Deployment of the guide member by creating separation between the anchor member 202 and the tip 110 (see
Referring now to
With the guide member 102 deployed (i.e. separated from the cavity evaluation device 100) and the device 100 removed from the patient, the guide wire 200 is used to facilitate introduction of the brachytherapy catheter device 600 by guiding the catheter through the existing opening in the soft tissue. As indicated above, the catheter shaft 601 includes a tip 608 with at least one opening 606 sized to receive the guide wire. Once inserted into the opening in the tip, the guide wire 200 is received by the associated lumen or tubular opening 606 as the brachytherapy catheter 600 is inserted into the soft tissue. Those skilled in the art will recognize that the flexibility of the guide wire 200 and resistance presented by the anchor member 202 in the soft tissue may be adjusted to achieve a desired result for a particular type of soft tissue, e.g., to present suitable resistance against movement. For example, the anchor member could be inflatable. The brachytherapy catheter 600 is eventually moved slidably along the guide wire to the extent that the tip 608 of the brachytherapy catheter contacts the anchor member 202, thereby indicating completion of that part of the procedure and helping to assure proper positioning of the brachytherapy catheter and associated dosing lumens with respect to the resected cavity 610. The inflatable member 602 is inflated after the tip of the catheter contacts the anchor member. The dosing lumens 604 are then used to deliver radiation therapy as already known in the art. The guide member 102 may be removed along with the brachytherapy catheter 600 once the treatment is completed. Alternatively, the guide member may be left in place if desired.
While the invention is described through the above exemplary embodiments, it will be understood by those of ordinary skill in the art that modification to and variation of the illustrated embodiments may be made without departing from the inventive concepts herein disclosed. Moreover, while the preferred embodiments are described in connection with various illustrative structures, one skilled in the art will recognize that the system may be embodied using a variety of specific structures. Accordingly, the invention should not be viewed as limited except by the scope and spirit of the appended claims.
This application is a continuation of and claims the benefit of priority of U.S. application Ser. No. 12/894,888, filed Sep. 30, 2010, now U.S. Pat. No. 9,352,172, entitled “Using a Guide Member to Facilitate Brachytherapy Device Swap”, the disclosure of which is hereby incorporated by reference herein.
Number | Name | Date | Kind |
---|---|---|---|
3324847 | Zoumboulis | Jun 1967 | A |
3502878 | Stewart | Mar 1970 | A |
3863073 | Wagner | Jan 1975 | A |
3872856 | Clayton | Mar 1975 | A |
3971950 | Evans et al. | Jul 1976 | A |
3975350 | Hudgin et al. | Aug 1976 | A |
4119094 | Micklus et al. | Oct 1978 | A |
4160906 | Daniels et al. | Jul 1979 | A |
4310766 | Finkenzeller et al. | Jan 1982 | A |
4350169 | Dutcher et al. | Sep 1982 | A |
4417576 | Baran | Nov 1983 | A |
4454106 | Gansow et al. | Jun 1984 | A |
4496557 | Malen et al. | Jan 1985 | A |
4559641 | Caugant et al. | Dec 1985 | A |
4571241 | Christopher | Feb 1986 | A |
4690677 | Erb | Sep 1987 | A |
4706269 | Reina et al. | Nov 1987 | A |
4706652 | Horowitz | Nov 1987 | A |
4744099 | Huettenrauch et al. | May 1988 | A |
4754745 | Horowitz | Jul 1988 | A |
4763642 | Horowitz | Aug 1988 | A |
4773086 | Fujita et al. | Sep 1988 | A |
4773087 | Plewes | Sep 1988 | A |
4819258 | Kleinman et al. | Apr 1989 | A |
4821725 | Azam et al. | Apr 1989 | A |
4821727 | Levene et al. | Apr 1989 | A |
4867741 | Portnoy | Sep 1989 | A |
4929470 | Rittenhouse et al. | May 1990 | A |
4969174 | Scheid et al. | Nov 1990 | A |
4989227 | Tirelli et al. | Jan 1991 | A |
4998917 | Geiser et al. | Mar 1991 | A |
4998930 | Lundahl | Mar 1991 | A |
5015247 | Michaelson | May 1991 | A |
5018176 | Romeas et al. | May 1991 | A |
RE33634 | Yanaki | Jul 1991 | E |
5029193 | Saffer | Jul 1991 | A |
5051904 | Griffith | Sep 1991 | A |
5059166 | Fischell et al. | Oct 1991 | A |
5078142 | Siczek et al. | Jan 1992 | A |
5084001 | Vant Hooft et al. | Jan 1992 | A |
5084015 | Moriuchi | Jan 1992 | A |
5084022 | Claude | Jan 1992 | A |
5106360 | Ishiwara et al. | Apr 1992 | A |
5112303 | Pudenz et al. | May 1992 | A |
5152747 | Olivier | Oct 1992 | A |
5163075 | Lubinsky et al. | Nov 1992 | A |
5164976 | Scheid et al. | Nov 1992 | A |
5167622 | Muto | Dec 1992 | A |
5199056 | Darrah | Mar 1993 | A |
5199939 | Dake et al. | Apr 1993 | A |
5227969 | Waggener et al. | Jul 1993 | A |
5236410 | Granov et al. | Aug 1993 | A |
5240011 | Assa | Aug 1993 | A |
5259847 | Trambert | Nov 1993 | A |
5289520 | Pellegrino et al. | Feb 1994 | A |
5302168 | Hess | Apr 1994 | A |
5312356 | Engelson et al. | May 1994 | A |
5314518 | Ito et al. | May 1994 | A |
5336178 | Kaplan et al. | Aug 1994 | A |
5342305 | Shonk | Aug 1994 | A |
5359637 | Webber | Oct 1994 | A |
5365562 | Toker | Nov 1994 | A |
5381504 | Novack et al. | Jan 1995 | A |
5411466 | Hess | May 1995 | A |
5415169 | Siczek et al. | May 1995 | A |
5417687 | Nardella et al. | May 1995 | A |
5422926 | Smith et al. | Jun 1995 | A |
5426685 | Pellegrino et al. | Jun 1995 | A |
5428658 | Oettingger et al. | Jun 1995 | A |
5429582 | Williams | Jul 1995 | A |
5452367 | Bick et al. | Sep 1995 | A |
5465733 | Hinohara | Nov 1995 | A |
5484384 | Fearnot | Jan 1996 | A |
5503613 | Weinberger | Apr 1996 | A |
5506877 | Niklason et al. | Apr 1996 | A |
5520646 | D'Andrea | May 1996 | A |
5526394 | Siczek et al. | Jun 1996 | A |
5535817 | Dunne | Jul 1996 | A |
5539797 | Heidsieck et al. | Jul 1996 | A |
5553111 | Moore et al. | Sep 1996 | A |
5562594 | Weeks | Oct 1996 | A |
5566221 | Smith et al. | Oct 1996 | A |
5592562 | Rooks | Jan 1997 | A |
5594769 | Pellegrino et al. | Jan 1997 | A |
5596200 | Sharma et al. | Jan 1997 | A |
5598454 | Franetzki et al. | Jan 1997 | A |
5603991 | Kupiecki et al. | Feb 1997 | A |
5609152 | Pellegrino et al. | Mar 1997 | A |
5611767 | Williams | Mar 1997 | A |
5616114 | Thornton et al. | Apr 1997 | A |
5621780 | Smith et al. | Apr 1997 | A |
5624395 | Mikhail et al. | Apr 1997 | A |
5627869 | Andrew et al. | May 1997 | A |
5653683 | D'Andrea | Aug 1997 | A |
5657362 | Giger et al. | Aug 1997 | A |
5662580 | Bradshaw et al. | Sep 1997 | A |
5668889 | Hara | Sep 1997 | A |
5704926 | Sutton | Jan 1998 | A |
5706327 | Adamkowski et al. | Jan 1998 | A |
5719952 | Rooks | Feb 1998 | A |
5720717 | D'Andrea | Feb 1998 | A |
5724400 | Swerdloff et al. | Mar 1998 | A |
5735264 | Siczek et al. | Apr 1998 | A |
5741253 | Michaelson | Apr 1998 | A |
5759173 | Preissman et al. | Jun 1998 | A |
5769086 | Ritchart et al. | Jun 1998 | A |
5782742 | Crocker et al. | Jul 1998 | A |
5800333 | Liprie | Sep 1998 | A |
5803895 | Kronholz et al. | Sep 1998 | A |
5803912 | Siczek et al. | Sep 1998 | A |
5818898 | Tsukamoto et al. | Oct 1998 | A |
5820594 | Fontirroche et al. | Oct 1998 | A |
5820717 | Siegenthaler | Oct 1998 | A |
5828722 | Ploetz et al. | Oct 1998 | A |
5851182 | Sahadevan | Dec 1998 | A |
5863284 | Klein | Jan 1999 | A |
5863285 | Coletti | Jan 1999 | A |
5872828 | Niklason et al. | Feb 1999 | A |
5878104 | Ploetz | Mar 1999 | A |
5896437 | Ploetz | Apr 1999 | A |
5899882 | Waksman et al. | May 1999 | A |
5908406 | Ostapchenko et al. | Jun 1999 | A |
5913813 | Williams et al. | Jun 1999 | A |
5916143 | Apple et al. | Jun 1999 | A |
5919473 | Elkhoury | Jul 1999 | A |
5924973 | Weinberger | Jul 1999 | A |
5931774 | Willaims et al. | Aug 1999 | A |
5935098 | Blaisdell et al. | Aug 1999 | A |
5986662 | Argiro et al. | Nov 1999 | A |
5993972 | Reich et al. | Nov 1999 | A |
6005907 | Ploetz | Dec 1999 | A |
6013038 | Pflueger | Jan 2000 | A |
6022308 | Williams | Feb 2000 | A |
6022325 | Siczek et al. | Feb 2000 | A |
6033357 | Ciezki et al. | Mar 2000 | A |
6036631 | McGrath et al. | Mar 2000 | A |
6050930 | Teirstein | Apr 2000 | A |
6056702 | Lorenzo | May 2000 | A |
6075879 | Roehrig et al. | Jun 2000 | A |
6083148 | Williams | Jul 2000 | A |
6086970 | Ren | Jul 2000 | A |
6091841 | Rogers et al. | Jul 2000 | A |
6093142 | Ciamacco, Jr. | Jul 2000 | A |
6095966 | Chomenky et al. | Aug 2000 | A |
6137527 | Abdel-Malek et al. | Oct 2000 | A |
6141398 | He et al. | Oct 2000 | A |
6143013 | Samson et al. | Nov 2000 | A |
6149301 | Kautzer et al. | Nov 2000 | A |
6175117 | Komardin et al. | Jan 2001 | B1 |
6196715 | Nambu et al. | Mar 2001 | B1 |
6200257 | Winkler | Mar 2001 | B1 |
6216540 | Nelson et al. | Apr 2001 | B1 |
6217565 | Cohen | Apr 2001 | B1 |
6219059 | Argiro | Apr 2001 | B1 |
6233473 | Shepherd et al. | May 2001 | B1 |
6234952 | Liprie | May 2001 | B1 |
6243441 | Zur | Jun 2001 | B1 |
6248122 | Klumb et al. | Jun 2001 | B1 |
6251059 | Apple et al. | Jun 2001 | B1 |
6256370 | Yavuz | Jul 2001 | B1 |
6256529 | Holupka et al. | Jul 2001 | B1 |
6267775 | Clerc et al. | Jul 2001 | B1 |
6272207 | Tang | Aug 2001 | B1 |
6282142 | Miyawaki | Aug 2001 | B1 |
6289235 | Webber et al. | Sep 2001 | B1 |
6292530 | Yavus et al. | Sep 2001 | B1 |
6306074 | Waksman et al. | Oct 2001 | B1 |
6319188 | Lovoi | Nov 2001 | B1 |
6327336 | Gingold et al. | Dec 2001 | B1 |
6341156 | Baetz et al. | Jan 2002 | B1 |
6375352 | Hewes et al. | Apr 2002 | B1 |
6378137 | Hassan et al. | Apr 2002 | B1 |
6390967 | Forman et al. | May 2002 | B1 |
6390968 | Harmon | May 2002 | B1 |
6390992 | Morris et al. | May 2002 | B1 |
6398708 | Hastings et al. | Jun 2002 | B1 |
6411836 | Patel et al. | Jun 2002 | B1 |
6413203 | Sahatjian | Jul 2002 | B1 |
6413204 | Winkler et al. | Jul 2002 | B1 |
6415015 | Nicolas et al. | Jul 2002 | B2 |
6416457 | Urick et al. | Jul 2002 | B1 |
6416492 | Nielson | Jul 2002 | B1 |
6442288 | Haerer et al. | Aug 2002 | B1 |
6443912 | Mazzola et al. | Sep 2002 | B1 |
6458069 | Tam et al. | Oct 2002 | B1 |
6458070 | Waksman et al. | Oct 2002 | B1 |
6459925 | Nields et al. | Oct 2002 | B1 |
6482124 | Winkler et al. | Nov 2002 | B2 |
6482142 | Winkler et al. | Nov 2002 | B1 |
6501819 | Unger et al. | Dec 2002 | B2 |
6512942 | Burdette et al. | Jan 2003 | B1 |
6527693 | Munro, III et al. | Mar 2003 | B2 |
6540655 | Chin et al. | Apr 2003 | B1 |
6556655 | Chichereau et al. | Apr 2003 | B1 |
6558390 | Cragg | May 2003 | B2 |
6579221 | Peterson | Jun 2003 | B1 |
6597762 | Ferrant et al. | Jul 2003 | B1 |
6605030 | Weinberger | Aug 2003 | B2 |
6607477 | Longton et al. | Aug 2003 | B1 |
6610013 | Fenster et al. | Aug 2003 | B1 |
6611575 | Alyassin et al. | Aug 2003 | B1 |
6615070 | Lee | Sep 2003 | B2 |
6616629 | Verin et al. | Sep 2003 | B1 |
6620111 | Stephens et al. | Sep 2003 | B2 |
6626849 | Huitema et al. | Sep 2003 | B2 |
6633674 | Gemperline et al. | Oct 2003 | B1 |
6638235 | Miller et al. | Oct 2003 | B2 |
6647092 | Eberhard et al. | Nov 2003 | B2 |
6652441 | Weinberger et al. | Nov 2003 | B2 |
6673006 | Winkler | Jan 2004 | B2 |
6685618 | Tam et al. | Feb 2004 | B2 |
6706014 | Banik et al. | Mar 2004 | B2 |
6723052 | Mills | Apr 2004 | B2 |
6744848 | Stanton et al. | Jun 2004 | B2 |
6746392 | Stiger et al. | Jun 2004 | B2 |
6748044 | Sabol et al. | Jun 2004 | B2 |
6749555 | Winkler et al. | Jun 2004 | B1 |
6749595 | Murphy | Jun 2004 | B1 |
6751285 | Eberhard et al. | Jun 2004 | B2 |
6752752 | Geitz | Jun 2004 | B2 |
6758824 | Miller et al. | Jul 2004 | B1 |
6770058 | Liprie | Aug 2004 | B1 |
6813334 | Koppe et al. | Nov 2004 | B2 |
6882700 | Wang et al. | Apr 2005 | B2 |
6885724 | Li et al. | Apr 2005 | B2 |
6912319 | Barnes et al. | Jun 2005 | B1 |
6913600 | Valley et al. | Jul 2005 | B2 |
6923754 | Lubock | Aug 2005 | B2 |
6940943 | Claus et al. | Sep 2005 | B2 |
6955641 | Lubock | Oct 2005 | B2 |
6970531 | Eberhard et al. | Nov 2005 | B2 |
6978040 | Berestov | Dec 2005 | B2 |
6983754 | Anderson et al. | Jan 2006 | B1 |
6987831 | Ning | Jan 2006 | B2 |
6999554 | Mertelmeier | Feb 2006 | B2 |
7098463 | Adamovics | Aug 2006 | B2 |
7107089 | Lee | Sep 2006 | B2 |
7110490 | Eberhard et al. | Sep 2006 | B2 |
7110502 | Tsuji | Sep 2006 | B2 |
7123684 | Jing et al. | Oct 2006 | B2 |
7127091 | Op De Beek et al. | Oct 2006 | B2 |
7142633 | Eberhard et al. | Nov 2006 | B2 |
7171255 | Holupka et al. | Jan 2007 | B2 |
7201715 | Burdette et al. | Apr 2007 | B2 |
7214178 | Lubock | May 2007 | B2 |
7245694 | Jing et al. | Jul 2007 | B2 |
7315607 | Ramsauer | Jan 2008 | B2 |
7319735 | Defreitas | Jan 2008 | B2 |
7322929 | Lovoi | Jan 2008 | B2 |
7323692 | Rowlands et al. | Jan 2008 | B2 |
7404791 | Linares et al. | Jul 2008 | B2 |
7407476 | Lubock et al. | Aug 2008 | B2 |
7413539 | Lubock et al. | Aug 2008 | B2 |
7430272 | Jing et al. | Sep 2008 | B2 |
7443949 | Defreitas et al. | Oct 2008 | B2 |
7465268 | Lubock et al. | Dec 2008 | B2 |
7476235 | Diederich et al. | Jan 2009 | B2 |
7497819 | White et al. | Mar 2009 | B2 |
7497820 | White et al. | Mar 2009 | B2 |
7513861 | Klein et al. | Apr 2009 | B2 |
7517310 | Lubock et al. | Apr 2009 | B2 |
7609806 | Defreitas et al. | Oct 2009 | B2 |
7630533 | Ruth et al. | Dec 2009 | B2 |
7662082 | White et al. | Feb 2010 | B2 |
7697660 | Ning | Apr 2010 | B2 |
7783006 | Stewart et al. | Aug 2010 | B2 |
7792245 | Hitzke et al. | Sep 2010 | B2 |
7869563 | Defreitas et al. | Jan 2011 | B2 |
7885382 | Stewart et al. | Feb 2011 | B2 |
7887476 | Hermann et al. | Feb 2011 | B2 |
7955246 | Lubock et al. | Jun 2011 | B2 |
8075469 | Lubock et al. | Dec 2011 | B2 |
8079946 | Lubock et al. | Dec 2011 | B2 |
8123722 | Chang et al. | Feb 2012 | B2 |
8137256 | Cutrer et al. | Mar 2012 | B2 |
8192344 | Lubock et al. | Jun 2012 | B2 |
8277370 | Quick | Oct 2012 | B2 |
8287442 | Quick | Oct 2012 | B2 |
8565374 | Defreitas et al. | Oct 2013 | B2 |
9180312 | Lubock et al. | Nov 2015 | B2 |
9248311 | Damarati | Feb 2016 | B2 |
9352172 | Benson | May 2016 | B2 |
9415239 | Lubock | Aug 2016 | B2 |
9579524 | Damarati | Feb 2017 | B2 |
20010016725 | Valley et al. | Aug 2001 | A1 |
20010038681 | Stanton et al. | Nov 2001 | A1 |
20010038861 | Hsu et al. | Nov 2001 | A1 |
20010049464 | Ganz | Dec 2001 | A1 |
20010051669 | McGhee | Dec 2001 | A1 |
20020012450 | Tsujii | Jan 2002 | A1 |
20020026090 | Kaplan et al. | Feb 2002 | A1 |
20020045893 | Lane et al. | Apr 2002 | A1 |
20020050986 | Inoue et al. | May 2002 | A1 |
20020055666 | Hunter et al. | May 2002 | A1 |
20020075997 | Unger et al. | Jun 2002 | A1 |
20020095114 | Palasis | Jul 2002 | A1 |
20020156342 | Burton et al. | Oct 2002 | A1 |
20020177804 | Saab | Nov 2002 | A1 |
20020177870 | Sepetka | Nov 2002 | A1 |
20030018272 | Treado et al. | Jan 2003 | A1 |
20030073895 | Nields et al. | Apr 2003 | A1 |
20030095624 | Eberhard | May 2003 | A1 |
20030144570 | Hunter et al. | Jul 2003 | A1 |
20030153803 | Harmon | Aug 2003 | A1 |
20030191491 | Duane et al. | Oct 2003 | A1 |
20030194050 | Eberhard | Oct 2003 | A1 |
20030194051 | Wang et al. | Oct 2003 | A1 |
20030194121 | Eberhard et al. | Oct 2003 | A1 |
20030210254 | Doan et al. | Nov 2003 | A1 |
20030215120 | Uppaluri et al. | Nov 2003 | A1 |
20040015193 | Lamson | Jan 2004 | A1 |
20040039437 | Sparer et al. | Feb 2004 | A1 |
20040054366 | Davison et al. | Mar 2004 | A1 |
20040066884 | Hermann Claus et al. | Apr 2004 | A1 |
20040066904 | Eberhard et al. | Apr 2004 | A1 |
20040087827 | Lubock | May 2004 | A1 |
20040094167 | Brady et al. | May 2004 | A1 |
20040101095 | Jing et al. | May 2004 | A1 |
20040109529 | Eberhard et al. | Jun 2004 | A1 |
20040116767 | Lebovic et al. | Jun 2004 | A1 |
20040147800 | Barber et al. | Jul 2004 | A1 |
20040171986 | Tremaglio, Jr. et al. | Sep 2004 | A1 |
20040215048 | Lubock | Oct 2004 | A1 |
20040260142 | Lovoi | Dec 2004 | A1 |
20040267157 | Miller et al. | Dec 2004 | A1 |
20050016771 | Mayes et al. | Jan 2005 | A1 |
20050049521 | Miller et al. | Mar 2005 | A1 |
20050059990 | Ayala et al. | Mar 2005 | A1 |
20050061771 | Murphy | Mar 2005 | A1 |
20050063509 | DeFreitas et al. | Mar 2005 | A1 |
20050078797 | Danielsson et al. | Apr 2005 | A1 |
20050080313 | Stewart et al. | Apr 2005 | A1 |
20050101823 | Linares et al. | May 2005 | A1 |
20050105679 | Wu et al. | May 2005 | A1 |
20050113681 | DeFreitas | May 2005 | A1 |
20050113715 | Schwindt et al. | May 2005 | A1 |
20050124843 | Singh | Jun 2005 | A1 |
20050129172 | Mertelmeier | Jun 2005 | A1 |
20050135555 | Claus et al. | Jun 2005 | A1 |
20050135664 | Kaufhold et al. | Jun 2005 | A1 |
20050182286 | Lubock | Aug 2005 | A1 |
20050226375 | Eberhard et al. | Oct 2005 | A1 |
20050240073 | Apffelstaedt et al. | Oct 2005 | A1 |
20050240074 | Lubock | Oct 2005 | A1 |
20050267320 | Barber et al. | Dec 2005 | A1 |
20050277577 | Hunter et al. | Dec 2005 | A1 |
20060014997 | Kindlein et al. | Jan 2006 | A1 |
20060020156 | Shukla | Jan 2006 | A1 |
20060020256 | Bell et al. | Jan 2006 | A1 |
20060030784 | Miller et al. | Feb 2006 | A1 |
20060074288 | Kelly | Apr 2006 | A1 |
20060098855 | Gkanatsios | May 2006 | A1 |
20060100475 | White et al. | May 2006 | A1 |
20060116546 | Eng | Jun 2006 | A1 |
20060129062 | Nicoson et al. | Jun 2006 | A1 |
20060136051 | Furst et al. | Jun 2006 | A1 |
20060149186 | Wantink | Jul 2006 | A1 |
20060155209 | Miller et al. | Jul 2006 | A1 |
20060167416 | Mathis et al. | Jul 2006 | A1 |
20060173233 | Lovoi | Aug 2006 | A1 |
20060173235 | Lim et al. | Aug 2006 | A1 |
20060205992 | Lubock et al. | Sep 2006 | A1 |
20060291618 | Eberhard et al. | Dec 2006 | A1 |
20070005003 | Patterson et al. | Jan 2007 | A1 |
20070030949 | Jing et al. | Feb 2007 | A1 |
20070036265 | Jing et al. | Feb 2007 | A1 |
20070055144 | Neustadter et al. | Mar 2007 | A1 |
20070076844 | Defreitas et al. | Apr 2007 | A1 |
20070106108 | Hermann et al. | May 2007 | A1 |
20070142694 | Cutrer et al. | Jun 2007 | A1 |
20070142779 | Duane | Jun 2007 | A1 |
20070167665 | Hermann et al. | Jul 2007 | A1 |
20070167666 | Lubock et al. | Jul 2007 | A1 |
20070191667 | Lubock et al. | Aug 2007 | A1 |
20070223651 | Wagenaar et al. | Sep 2007 | A1 |
20070225600 | Weibrecht | Sep 2007 | A1 |
20070242800 | Jing | Oct 2007 | A1 |
20070270627 | Cutrer et al. | Nov 2007 | A1 |
20080009659 | Smith et al. | Jan 2008 | A1 |
20080019581 | Gkanatsios | Jan 2008 | A1 |
20080045833 | Defreitas | Feb 2008 | A1 |
20080057298 | Finley | Mar 2008 | A1 |
20080064915 | Lubock | Mar 2008 | A1 |
20080071212 | Lubock et al. | Mar 2008 | A1 |
20080086083 | Towler | Apr 2008 | A1 |
20080091055 | Nguyen et al. | Apr 2008 | A1 |
20080101537 | Sendai | May 2008 | A1 |
20080112534 | DeFreitas et al. | May 2008 | A1 |
20080130979 | Ren | Jun 2008 | A1 |
20080177127 | Allan et al. | Jul 2008 | A1 |
20080188705 | Lubock et al. | Aug 2008 | A1 |
20080221384 | Chi Sing et al. | Sep 2008 | A1 |
20080221444 | Ritchie et al. | Sep 2008 | A1 |
20080228023 | Jones et al. | Sep 2008 | A1 |
20080228024 | Jones et al. | Sep 2008 | A1 |
20080228025 | Quick | Sep 2008 | A1 |
20080228150 | Jones et al. | Sep 2008 | A1 |
20080281142 | Lubock et al. | Nov 2008 | A1 |
20080281143 | Lubock et al. | Nov 2008 | A1 |
20080287801 | Magnin et al. | Nov 2008 | A1 |
20090003519 | Defreitas | Jan 2009 | A1 |
20090010384 | Jing | Jan 2009 | A1 |
20090030259 | Quick | Jan 2009 | A1 |
20090080594 | Brooks | Mar 2009 | A1 |
20090080602 | Brooks | Mar 2009 | A1 |
20090093821 | Edmundson | Apr 2009 | A1 |
20090124845 | Lubock et al. | May 2009 | A1 |
20090135997 | Defreitas | May 2009 | A1 |
20090156880 | Allan et al. | Jun 2009 | A1 |
20090156882 | Chi Sing et al. | Jun 2009 | A1 |
20090171157 | Diedrich et al. | Jul 2009 | A1 |
20090188098 | Acosta et al. | Jul 2009 | A1 |
20090198095 | Acosta et al. | Aug 2009 | A1 |
20090213987 | Stein et al. | Aug 2009 | A1 |
20090268865 | Ren | Oct 2009 | A1 |
20090296882 | Gkanatsios | Dec 2009 | A1 |
20090304147 | Jing et al. | Dec 2009 | A1 |
20100048977 | Sing et al. | Feb 2010 | A1 |
20100054400 | Ren | Mar 2010 | A1 |
20100069878 | Parsai et al. | Mar 2010 | A1 |
20100086188 | Ruth | Apr 2010 | A1 |
20100150306 | Defreitas et al. | Jun 2010 | A1 |
20100195882 | Ren | Aug 2010 | A1 |
20100204534 | Damarati | Aug 2010 | A1 |
20100204535 | Damarati | Aug 2010 | A1 |
20100226475 | Smith | Sep 2010 | A1 |
20100268029 | Phan | Oct 2010 | A1 |
20100286465 | Benson | Nov 2010 | A1 |
20100290585 | Eliasson | Nov 2010 | A1 |
20110069809 | Defreitas et al. | Mar 2011 | A1 |
20120046647 | Matsukuma et al. | Feb 2012 | A1 |
20120071705 | Lubock et al. | Mar 2012 | A1 |
20120088952 | Lubock et al. | Apr 2012 | A1 |
20120178983 | Benson | Jul 2012 | A1 |
20130225902 | White | Aug 2013 | A1 |
20170080252 | Lubock et al. | Mar 2017 | A1 |
Number | Date | Country |
---|---|---|
2539553 | Mar 1977 | DE |
0340881 | Oct 1992 | EP |
0536440 | Apr 1993 | EP |
0642766 | Mar 1995 | EP |
0693293 | Jan 1996 | EP |
0719571 | Jul 1996 | EP |
775467 | May 1997 | EP |
0853957 | Jul 1998 | EP |
0867200 | Sep 1998 | EP |
0982001 | Mar 2000 | EP |
1051990 | Nov 2000 | EP |
1070514 | Jan 2001 | EP |
1402922 | Mar 2004 | EP |
1428473 | Jun 2004 | EP |
1541188 | Jun 2005 | EP |
1618924 | Jan 2006 | EP |
1759637 | Mar 2007 | EP |
10137250 | May 1998 | JP |
2001120561 | May 2001 | JP |
2177350 | Dec 2001 | RU |
WO 9005485 | May 1990 | WO |
WO 9210932 | Jul 1992 | WO |
WO 9309724 | May 1993 | WO |
WO 9520241 | Jul 1995 | WO |
WO 9712540 | Apr 1997 | WO |
WO 9719723 | Jun 1997 | WO |
WO 9745053 | Dec 1997 | WO |
WO 9816903 | Apr 1998 | WO |
WO 9815315 | Apr 1998 | WO |
WO 9911325 | Mar 1999 | WO |
WO 9933515 | Jul 1999 | WO |
WO 9934869 | Jul 1999 | WO |
WO 9942163 | Aug 1999 | WO |
WO 0051484 | Sep 2000 | WO |
WO 0114011 | Mar 2001 | WO |
WO 0143826 | Jun 2001 | WO |
WO 0158346 | Aug 2001 | WO |
WO 0209599 | Feb 2002 | WO |
WO 02069862 | Sep 2002 | WO |
WO 03020114 | Mar 2003 | WO |
WO 2004043531 | May 2004 | WO |
WO 2004043535 | May 2004 | WO |
WO 2005037363 | Apr 2005 | WO |
WO 2005039655 | May 2005 | WO |
WO 2005039665 | May 2005 | WO |
WO 2005051197 | Jun 2005 | WO |
WO 2005067442 | Jul 2005 | WO |
WO 2005110230 | Nov 2005 | WO |
WO 2005112767 | Dec 2005 | WO |
WO 2006055830 | May 2006 | WO |
WO 2006058160 | Jun 2006 | WO |
WO 2007027831 | Mar 2007 | WO |
WO 2007143560 | Dec 2007 | WO |
WO 2008067557 | Jun 2008 | WO |
WO 09079170 | Jun 2009 | WO |
Entry |
---|
“DuPont Teflon PFA HP Plus”, XP007904995:retrieved from the internet: URL: http://www2.dupont.com/Teflon_Industrial/en_US/assets/downloads/ h88800.pdf; retrieved on Jun. 19, 2008, by Authorized Officer in International Application PCT/US2008/003364, 4 pgs. |
“Essentials for life: Senographe Essential Full-Field Digital Mammography system”, GE Health-care Brochure, MM-0132-05.06-EN-US, 2006, 12 pgs. |
“Filtered Back Projection,” (NYGREN) published May 8, 2007; URL:http://web.archive.org/web/19991010131715/http://www.owlnet.rice.edu/-.about.e1ec539/Projects97/cult/node2.html, 2 pgs. |
“Lorad Selenia” Document B-BI-SEO US/Intl (May 2006), copyright Hologic 2006, 12 pgs. |
“Variable shield for radiation-therapy sourcewire and centering catheter”, Research disclosure, Mason Publications, Hampshire, GB, vol. 438, No. 48, Oct. 2000, XP007126916, 1 page. |
Abstracts of the 11th International Conference on Brain tumor Research and Therapy Oct. 31-Nov. 3, 1995, Silverado Country Club and Resort, Napa, California, Journal of Neuro-Oncology 28, p. 72, 1996, 2 pages all together. |
Akagi, Y, et al.,“Optimum Fractionation for High-Dose-Rate Endoesophageal Brachytherapy Following External Irradiation of Early State Esophageal Cancer”, Int. J. Radiation Oncology Biol. Phys., vol. 43, 1999, pp. 525-530, Elsevier Science, Inc. |
Ashpole et al., “A New Technique of Brachytherapy for Malignant Gliomas with Caesium-137: A New Method Utilizing a Remote Afterloading System,” Clinical Oncology, 1990, vol. 2, pp. 333-337. |
Astrahan, Melvin A., PhD et al., “Optimization of Mammosite therapy”, Int. J. Radiation Oncology Biol. Phys, vol. 58, No. 1, pp. 220-232, 2004. |
Bowsher. W. G., et al., “Update on Urology-Prostate Cancer. 4-Treatment of Local Disease”. European Journal of Surgical Oncology. 1995 pp. 679-682. vol. 21. No. 6. |
Chan, Heang-Ping et al., “ROC study of the effect of stereoscopic imaging on assessment of breast lesions”, Medica Physics, vol. 32, No. 4, Apr. 2005, 7 pgs. |
Cole, Elodia, et al., “The Effects of Gray Scale Image Processing on Digital Mammography Interpretation Performance”, Academic Radiology, vol. 12, No. 5, pp. 585-595, May 2005. |
Cuttino, L. W., et al.,“CT-Guided Multi-Catheter Insertion Technique for Partial Breast Brachytherapy: Reliable Target Coverage and Dose Homogeneity”, Brachy1herapy 4, 2005, pp. 10-17, Elsevier. |
Das, R. K., et al., “3D-CT-Based High-Dose-Rate Breast Brachytherapy Implants: Treatment Planning and Quality Assurance”, Int. J. Radiation Oncology Biol. Phys. 2004, pp. 1224-1228, vol. 59, No. 4, Elsevier Inc. |
Debicki, M. P., et al., “Localized Current Field Hyperthermia in Carcinoma of the Cervix: 3-D Computer Simulation of SAR Distribution”. International Journal of Hyperthermia. 1999. pp. 427-440. vol. 15. No. 5. |
Demanes, D. J . et al., “The Use and Advantages of a Multichannel Vaginal Cylinder in High-Dose-Rate Brachytherapy”. Int. J. Radiation Oncology Biol. Phys. (1999). pp. 211-219. vol. 44. No. 1. Elsevier Science Inc. |
Dempsey, J. F. et al., “Dosimetric Properties of a Novel Brachytherapy Balloon Applicator for the Treatment of Malignant Brain-Tumor Resection-Cavity Margins”, Int. J. Radiation Oncology Biol. Phys., May 1998, pp. 421-429, vol. 42. No. 2. Elsevier. |
Devic et al., “Advantages of Inflatable Multichannel Endorectal Applicator in the Neo-Adjuvant Treatment of Patients With Locally Advanced Rectal Cancer With HOR Brachytherapy”, Journal of Applied Clinical Medical Physics, Spring 2005, pp. 44-49, vol. 6, No. 2. |
Digital Clinical Reports, Tomosynthesis, GE Brochure 98/5493, Nov. 1998, 8 pgs. |
Edmundson,Gregory K. et al., “Dosimetric Characteristics of the Mammosite RTS, a New Breast Brachytherapy Applicator”, Int. J. Radiation Oncology Biol. Phys., vol. 52, No. 4, pp. 1132-1139, 2002. |
Federica Pediconi et al., “Color-coded automated signal intensity-curve for detection and characterization of breast lesions: Preliminary evaluation of a new software for MR-based breast imaging”, International Congress Series 1281 (2005) 1081-1086. |
Fowler, J. E., “Brief Summary of Radiobiological Principles in Fractionated Radiotherapy”, Seminars in Radiation Oncology, Jan. 1992, pp. 16-21, vol. 2, No. 1, W. B. Saunders Company. |
Friedman, M, et al., “A New Technic for the Radium Treatment of Carcinoma of the Bladder”, Presented at the Thirty-fourth Annual Meeting of the Radiological Society of North America, Dec. 5-10, 1948, pp. 342-362. |
Friedman, M, et al., “Irradiation of Carcinoma of the Bladder by a Central Intracavitary Radium or Cobalt 60 Source (The Walter Reed Technique)”, Presented at the Annual Meeting of the American Radium Society, 1955, pp. 6-31. |
Garipagaoglu, M. et al., “Geometric and Dosimetric Variations of ICRU Bladder and Rectum Reference Points in Vaginal Cuff Brachytherapy Using Ovoids”, Int. J. Radiation Oncology Biol. Phys. 2004, pp. 1607-1615. Elsevier Inc. |
Gaspar, L. E., et al., “Esophageal Brachytherapy”, Principles and Practice of Brachytherapy, 1997, pp. 305-321, Futrua Publishing Company, Inc., Armouk, New York. |
Glasgow, G. P., et al. “Remote Afterloading Technology”, AAPM Report No. 41, 1993, pp. i-vi and 1-107, American Institute of Physics, Inc., 116 pgs. |
Gutin, P.H. et al., “A coaxial catheter system for afterloading radioactive sources for the interstitial irradiation of brain tumors”, J. Neurosur, vol. 56, pp. 734-735, 1982. |
Hall, J. W., et al., “Histologic Changes in Squamous-Cell Carcinoma of the Mouth and Oropharynx Produced by Fractionated External Roentgen Irradiation”, Radiological Society of North America, 1948, pp. 318-350, Mar. 3, 1950. |
Harada, T, et al.,“Transcystoscopic Intracavitary irradiation for Carcinoma of the Bladder: Technique and Preliminary Clinical Results”, The Journal of Urology, Oct. 1987, pp. 771-774, vol. 138, No. 4, The Williams & Wilkins Co. |
Harper, Paul V., “Some Therapeutic Applications of Radioisotopes”, Journal of the Mississippi State Medical Association, Oct. 1966, vol. VII, pp. 526-533. |
Hewitt, C. B., et al., “Intracavitary Radiation in the Treatment of Bladder Tumors”, The Journal of Urology, vol. 107, Apr. 1972, pp. 603-606, The Williams & Wilkins Co. |
Hewitt, C. B., et al., “Update on Intracavitary Radiation in the Treatment of Bladder Tumors”, The Journal of Urology; Official Journal of the American Urological Association, Inc., 1981, pp. 323-325, vol. 126 September, The Williams & Wilkins Co. |
Hieshima,G. B., et al. “A Detachable Balloon for Therapeutic Transcatheter Occlusions 1”, Technical Notes, Jan. 1981, pp. 227-228, vol. 138. |
Hine, G. J., et al., “Isodose Measurements of Linear Radium Sources in Air and Water by Means of an Automatic Isodose Recorder”, The American Journal of Roentgenology and Radium Therapy, 1950, pp. 989-998, vol. 64, No. 6, The Societies. |
Hoshino, T., “Brain Tumor Research Center”, Abstracts of the 11th Conference on Brain Tumor Research and Therapy, Journal of Neuro-Oncology 28, 1996, pp. 31-113. |
Johannesen, T.B. et al, “Intracavity Fractioned Balloon Brachytherapy in Glioblastoma”, Acta Neurochir (Wien) (1999) 141: 127-133. |
Kaufman, N., “Remote Afterloading Intraluminal Brachytherapy in the Treatment of Rectal, Rectosigmoid, and Anal Cancer: A Feasibility Study”, International Journal of Radiation Oncology, Biology, Physics, Sep. 1989, pp. 663-668, vol. 17, Issue 3, Pergamon Press pic. |
Kita et al., “Correspondence between different view breast X-rays using simulation of breast deformation”, Proceedings 1998 IEE Computer Society Conference on Computer Vision and Pattern Recognition, Santa Barbara, CA, Jun. 23-25, 1998, pp. 700-707. |
Kolotas., C. et al., “CT Guided Interstitial High Dose Rate Brachytherapy for Recurrent Malignant Gliomas”. The British Journal of Radiology. 72. (1999), pp. 805-808. |
Kuettel, M. R. et al.. “Treatment of Female Urethral Carcinoma in Medically Inoperable Patients Using External Beam Irradiation and High Dose Rate Intracavitary Brachytherapy”, The Journal of Urology. May 1997, pp. 1669-1671, vol. 157, The American Urological Association, Inc. |
Lewis, J, et al., “Intracranial Brachytherapy Using a High Dose Rate Microselectron”, Northern Centre for Cancer Treatment, Dept. of Neurosciences, Regional Medical Physics Department, Newcastle General Hospital, Newcastle Upon Tyne, UK, Radiation and Oncology, vol. 39, Supplement 1, May 1996, pp. 45-45, 1 page, p. 179. |
Low-Beer, B. V. A., “Radioisotope Therapy”, “The Clinical Use of Radioactive Isotopes”, 1950, pp. 284-349, Charles C. Thomas, Publisher, Springfield, Illinois, U.S.A., See pp. 343-349. |
Low-Beer, B. V. A., “The Therapeutic Use of Radioactive Isotopes”, “Practical Therapeutics”, Dec. 1954, pp. 69-87, vol. X, No. 6. |
Mammographic Accreditation Phantom, http://www.cirsinc.com/pdfs/015cp.pdf, (2006), 2 pgs. |
Marshall V. F., et al., “Current Clinical Problems Regarding Bladder Tumors”, Symposium on Bladder Tumors, 1956, pp. 543-550, 9/3/May-Jun, J.B. Lippincott Co, Etc. |
Micheletti, E., et al., “High-Dose-Rate Brachytherapy for Poor-Prognosis, High-Grade Glioma: (Phase II) Preliminary Results”, Tumori, 1996, pp. 339-344. |
Muller, J. H., “Radiotherapy of Bladder Cancer by Means of Rubber Balloons Filled In Situ With solutions of a Radioactive Isotope (Co60)”, Cancer, A Journal of the American Cancer Society, Jul.-Aug. 1955, pp. 1035-1043, vol. 8, No. 4, J.B. Lippincott Company, Philadelphia. |
Nag, S, “Modern Techniques of Radiation Therapy for Endometrial Cancer”, Clinical Obstetrics and Gynecology, Sep. 1996, pp. 728-744, vol. 39, No. 3, Lippincott-Raven Publishers. |
Nag, S., et al., “Perineal Template Interstitial Barchytherapy Salvage for Recurrent Endometrial Adenocarcinoma Metastatic to the Vagina”, Necologic Oncology 66, 1997, pp. 16-19, Article No. G0974722, Academic Press. |
Nag, S., et al., “Remote Controlled High Dose Rate Brachytherapy”, Critical Reviews in Oncology/Hematology 22, 1996, pp. 127-150, Elsevier Science Ireland Ltd. |
Nag, S., et al., “The Future of High Dose Rate Brachytherapy”, High Dose Rate Brachytherapy: A Textbook, 1994, pp. 447-453, Futura Publishing Company, Inc. , Armonk, New York 10504. |
Nath, Ph.D. et al., “Development of an 241 Am Applicator for Intracavitary Irradiation of Gynecologic Cancers”, I.J. Radiation Oncology Biol. Phys., May 1988, vol. 14, p. 969-978. |
Pernot, M., “Combined Surgery and Brachytherapy in the Treatment of Some Cancers of the Bladder (Partial Cystectomy and Interstitial Iridium—192)”, Radiotherapy & Oncology, 1996, pp. 115-120, Elsevier Science Ireland Ltd. |
Rotman, M., et al., “The Intracavitary Applicator in Relation to Complications of Pelvic Radiation—The Ernst System”, Int. J. Radiation Oncology Biol. Phys., 1978, pp. 951-956, vol. 4, Pergamon Press Inc. |
Russel, A.H., et al, “Intracavitary Irradiation for Carcinoma of the Urinary Bladder: Rationale, Technique, and Preliminary Results”, Int. J. Radiation Oncology. Phys., 1984, pp. 215-219, vol. 10, Pergamon Press Ltd. |
Senographe 700 & 800T (GE); 2-page download on Jun. 22, 2006 from www.gehealthcare.com/inen/rad/whe/products/mswh800t.html.; Figures 1-7 on 4 sheets re lateral shift compression paddle, 2 pgs. |
Slevin. N. J. et al., “Intracavitary Radiotherapy Boosting for Nasopharynx Cancer”, The British Journal of Radiology, 70, Apr. 1997, pp. 412-414. |
Smith, A., “Fundamentals of Breast Tomosynthesis”, White Paper, Hologic Inc., WP-00007, Jun. 2008, 8 pgs. |
Sneed. P. K. et al., “Interstitial Brachytherapy Procedures for Brain Tumors”, Seminars in Surgical Oncology 1997; 13: 157-166. Wiley-Liss. Inc. |
Stubbs, J.B., et al.,“Preclinical Evaluation of a Novel Device for Delivering Brachytherapy to the Margins of Resected Brain Tumor Cavities”, J. Neurosurg 96, Feb. 2002, pp. 335-343, vol. 96. |
Sylvester, J., et al., “Interstitial Implantation Techniques in Prostate Cancer”, Journal of Surgical Oncology 1997; 66: 65-75. Wiley-Liss. Inc. |
Symon et al., “Individual Fraction Optimization vs. First Fraction Optimization for Multichannel Applicator Vaginal Cuff High-Dose-Rate Brachytherapy”, pp. 211-215, Brachytherapy 5 (2006), Elsevier. |
Tan, L. T. et al., “Radical Radiotherapy for Carcinoma of the Uterine Cervix Using External Beam Radiotherapy and a Single Line Source Brachytherapy Technique: The Clatterbridge Technique”, The British Journal of Radiology, 70, Dec. 1997, pp. 1252-1258. |
Tanderup et al. “Multi-Channel Intracavitary Vaginal Brachytherapy Using Three-Dimensional Optimization of Source Geometry”, Radiation & Oncology Journal of the European Society for Therapeutic Radiology and Oncology, 2004, pp. 81-85, Radiotherapy and Oncology 70 (2004), Elsevier Ireland Ltd. |
Vicini, F. A., et al, “Dose-Volume Analysis for Quality Assurance of Interstitial Brachytherapy for Breast Cancer”, Int. J. Radiation Oncology Biol. Phys., vol. 45, 1999, pp. 803-810, Elsevier Science Inc. |
Voung, T, et al., “High-Dose-Rate Endorectal Brachytherapy in the Treatment of Loacally Advanced Rectal Carcinoma: Technical Aspects”, Brachytherapy 4, 2005, pp. 230-235, Elsevier. |
Walton, R. J., “Therapeutic Uses of Radioactive Isotopes in the Royal Cancer Hospital”, The British Journal of Radiology, 1950, pp. 559-599, William Heinemann, Publisher. |
Walton, R. J., et al., Radioactive Solution (24Na and 82 Br) in the Treatment of Carcinoma of the Bladder:, British Medical Bulletin, 1952, pp. 158-165, Medical Dept., The British Council. |
Wang, C. C., “Carcinoma of the Nasopharynx”, Radiation Therapy of Head and Neck Neoplasms, 1997, pp. 257-280, Chapter 10, Wiley-Liss, Inc. |
Wheeler, F.W. et al. (2006), “Micro-Calcification Detection in Digital Tomosynthesis Mammography”, Proceedings of SPIE, Conf-Physics of Semiconductor Devices, Dec. 11, 2001 to Dec. 15, 2001, Delhi, SPIE, US, vol. 6144, Feb. 13, 2006, 12 pgs. |
Wolf, C. D., et al., “A Unique Nasopharynx Brachytherapy Technique”, Official Journal of the American Association of Medical Dosimetrists, 1990, pp. 133-136, vol. 15, Issue No. 3., Pergamon Press. |
Wu, Tao et al., “Tomographic mammography using a limited number of low-dose cone-beam images”, Medical Physics, AIP, Melville, NY, vol. 30, No. 3, Mar. 1, 2003, pp. 365-380. |
Xu, Z., et al., “Calculation of Dose Distribution Near an Innovative Concentric Balloon Catheter for Endovascular Brachytherapy”, Cardiovascular Radiation Medicine 2, 2000, pp. 26-31, Elsevier Science Inc. |
Yin, W., “Brachytherapy of Carcinoma of the Esophagus in China, 1970-1974 and 1982-1984”, Brachytherapy HOR and LOR, May 4-6, 1989, pp. 52-56. |
Number | Date | Country | |
---|---|---|---|
20160287902 A1 | Oct 2016 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 12894888 | Sep 2010 | US |
Child | 15167589 | US |