Claims
- 1. A vaccine against hepatitis B disease comprising an effective amount of a polypeptide and a physiologically acceptable diluent, wherein said polypeptide has the preS-1 domain lacking amino acids 2-15, the preS-2 domain and the S domain.
RELATED APPLICATION
This patent application is a continuation-in-part of our copending patent application, Ser. No. 824,405 filed Jan. 31, 1986 now U.S. Pat. No. 4,816,564.
US Referenced Citations (9)
Foreign Referenced Citations (1)
Number |
Date |
Country |
0198474 |
Oct 1986 |
EPX |
Non-Patent Literature Citations (4)
Entry |
Purcell et al., Hepabology 5(1) 1985, pp. 159-163. |
Milich et al., PNAS 82, 1985, pp. 8168-8172. |
Michel et al. PNAS, 1984, pp. 7708-7712. |
Wong et al., J. Virology 55(1) 1985, pp. 223-231. |
Continuations (1)
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Number |
Date |
Country |
Parent |
824405 |
Jan 1986 |
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