Patent Application
20250009405
The present invention relates to the technical field of cryoablation, and in particular to a cryoablation needle with an adjustable vacuum wall position.
Cryoablation is a treatment approach that uses low temperature to destroy diseased tissues, which is considered to be an efficient and minimally invasive method to treat malignant tumors. The cryoablation is easy to operate, has few complications, and can effectively relieve pain. At the same time, ice balls formed by ablation have clear boundaries and are easy to observe, and lesions near large blood vessels or important organs can be safely ablated. The cryoablation may also adopt a multi-needle freezing manner, so that a wider ablation range is achieved, which is suitable for large lesions and irregular lesions.
In the process of cell freezing, ice crystals are firstly formed outside cells, which causes the concentration of extracellular solute to increase, resulting in a hypertonic environment, and water in the cells enters the outside of the cells, resulting in intracellular dehydration. The cells that lose water become shrunk and cell membranes are deformed, resulting in a “solution damage” in a high-concentration toxic environment. At the same time, ice crystals formed in the cells directly damage organelles and the cell membranes, causing further necrosis, commonly known as an “intracellular ice damage”. The intracellular ice damage directly damages cell structures, and therefore is more destructive to the cells. Generally, the lower a cooling rate of the cells, the greater the probability of the “solution damage”, and the higher the cooling rate, the easier it is to induce the “intracellular ice damage”. Therefore, the higher cooling rate is generally pursued in the process of tumor cryoablation, which can kill tumors more thoroughly and greatly save surgery time.
The development of the cryoablation has undergone three stages. The first stage is a liquid nitrogen conveying and refrigeration technology, which conveys liquid nitrogen at −196° C. to a needle tip of a cryoablation needle by a low driving pressure to achieve the purpose of cryoablation. Because a cold source of this technology completely relies on the liquid nitrogen, which is located in a main machine or liquid nitrogen barrel and has a long conveying distance from the needle tip, during the liquid nitrogen conveying process, only when a whole conveying pipeline reaches −196° C., temperature of the needle tip can reach −196° C. Therefore, the cooling rate of liquid nitrogen refrigeration is the lowest in the prior art. The second stage is a direct throttling refrigeration technology, which uses the principle of “Joule Thompson Effect” (J-T for short), and conveys ultra-high pressure gas at room temperature to the J-T slot (a capillary tube that produces the J-T effect) inside the cryoablation needle to directly throttle to produce low temperature. The cooling rate of this technology is relatively the highest in the prior art. However, structures such as the J-T slot and a finned tube inside the needle tip may consume a part of cold, thus prolonging cooling time. In addition, the ultra-high pressure gas used is not highly popularized and is expensive, resulting in difficulty in the promotion of this technology. The third stage is a pre-cooled throttling refrigeration technology, the principle of which is to pre-cool normal industrial gas that is at room temperature by a supporting main machine, and then convey pre-cooled normal industrial gas to the J-T slot inside the cryoablation needle to produce ablation temperature that is lower than preset temperature by throttling. This technology solves the problem that gas sources are expensive and scarce. Furthermore, this technology combines a throttling refrigeration technology, and thus the cooling rate thereof is obviously higher than that of the liquid nitrogen refrigeration technology, but is still lower than that of the direct throttling refrigeration technology.
For problems existing in the prior art, the present invention provides a cryoablation needle with an adjustable vacuum wall position, to resolve the problem of low cooling rate in the prior art.
In order to resolve the above technical problem, the present invention is implemented through the following technical solutions:
The present invention provides a cryoablation needle with an adjustable vacuum wall position, including a vacuum wall, a J-T slot and a vacuum wall adjusting apparatus, where
Preferably, the vacuum wall adjusting apparatus includes: a first sliding block and a first sliding block guiding portion;
Preferably, the cryoablation needle with the adjustable vacuum wall position further includes: a first sealing assembly, where the first sealing assembly is hermetically connected to a proximal end of the inner tube, the proximal end of the inner tube being an end of the inner tube far away from the needle tip; and
Preferably, the first sealing assembly includes: a sealing ring, a sealing slot and a sealing press piece, where
Preferably, the cryoablation needle with the adjustable vacuum wall position further includes: a spring and a clamping piece, where
Preferably, the cryoablation needle with the adjustable vacuum wall position further includes: a first handle, wherein the first handle includes: a front handle section and a rear handle section;
Preferably, the clamping piece includes: a hand-held portion and a C-shaped ring, where
Preferably, the vacuum wall includes: a front vacuum wall section and a rear vacuum wall section, from a distal end to a proximal end of the vacuum wall, the front vacuum wall section and the rear vacuum wall section are sequentially distributed, and the front vacuum wall section and the rear vacuum wall section are capable of moving relatively; the needle tip is located at the front vacuum wall section;
Preferably, the vacuum wall adjusting apparatus includes: a second sliding block and a second sliding block guiding portion;
Preferably, the cryoablation needle with the adjustable vacuum wall position further includes: a second sealing assembly, where the second sealing assembly is arranged between the front vacuum wall section and the rear vacuum wall section, and is configured to form a dynamic seal between the front vacuum wall section and the rear vacuum wall section.
Preferably, the cryoablation needle with the adjustable vacuum wall position further includes: a shifting block and a second handle, where the second handle includes: a handle adjusting slot;
Preferably, the vacuum wall further includes: an outer tube and a gasket, where
Preferably, an outer diameter of the outer tube is greater than an outer diameter of the needle rod, and an inner diameter of the outer tube is greater than an inner diameter of the needle rod; and
Preferably, the cryoablation needle with the adjustable vacuum wall position further includes: a temperature measuring wire, where
Compared with the prior art, the present invention has the following advantages:
(1) According to the cryoablation needle with the adjustable vacuum wall position provided in the present invention, the vacuum wall is adjustable in position, and at least includes the two adjusting positions, and freezing is started after the J-T slot is returned to the inside of the vacuum insulation area, so that all conveying pipelines at a main machine side and a cryoablation needle side can be pre-purged (cooled), and no cold is consumed at the target area during a pre-purging process. Therefore, all cold is used for cooling the conveying pipelines, and thus the rate of this conveying pipeline cooling process is the highest. Furthermore, no cold is released at the target area during the pre-purging process, so that there are no frosting and freezing phenomena in the target area, and then formal surgery can be performed directly.
(2) According to the cryoablation needle with the adjustable vacuum wall position provided in the present invention, the distal end of the vacuum wall is adjustable in position, and at least includes the two adjusting positions, only the target area of the vacuum wall of the pre-purged cryoablation needle is not cooled, and after the J-T slot is returned to the inside of the target area, all heat loads only come from the target area and tumor tissues outside the target area. Therefore, the cooling rate of this freezing process can be greatly increased.
(3) According to the cryoablation needle with the adjustable vacuum wall position provided in the present invention, after a needling test procedure ends, a pre-purging mode can be kept enabled, the inside (the distal end of the J-T slot) of the vacuum insulation area is kept at the lowest temperature. Since the target area does not release any cold, operations such as puncturing, scanning and positioning can be performed, and then the cryoablation needle is adjusted to a freezing mode after the puncturing is in place. In this case, the inside of the target area is directly reduced from the room temperature to the lowest temperature instantly. Therefore, ultimate rapid cooling of the formal surgery can be achieved.
(4) The cryoablation needle with the adjustable vacuum wall position provided in the present invention is wide in application range, and can be applied to all existing cryoablation technologies: liquid nitrogen conveying and refrigeration technology, direct throttling refrigeration technology and pre-cooled throttling refrigeration technology. The cryoablation needle with the adjustable vacuum wall position is not only applicable to percutaneous puncture cryoablation instruments, but also applicable to cryoablation instruments of natural orifice transluminal surgery.
Certainly, implementing any product of the present invention does not necessarily need to simultaneously achieve all the advantages described above.
In order to explain the technical solutions in the embodiments of the present invention or in the prior art more clearly, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings in the following description are merely some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.
The technical solutions in embodiments of the present invention will be clearly and fully described in combination with the drawings of the embodiments of the present invention; it is obvious that the described embodiments are only a part of, and not all embodiments of, present invention. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts should fall within the protection scope of the present invention.
In the description of the specification of the present invention, it should be understood that the term “upper portion”, “lower portion”, “upper end”, “lower end”, “upper surface”, “lower surface” or the like indicates an orientation or positional relationship based on that shown in the drawings, which is merely for ease of description and simplicity of description, and is not intended to indicate or imply that the apparatus or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and therefore cannot be construed as a limitation on the present invention.
In the description of the specification of the present invention, the terms “first” and “second” are used for descriptive purposes only, and cannot be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined with “first” and “second” may explicitly or implicitly include one or more of the features.
In the description of the present invention, “a plurality of” means multiple, such as two, three, four or the like, unless specifically defined otherwise.
The technical solutions of the present invention will be described in detail below by specific embodiments. The following several specific embodiments may be mutually combined, and same or similar concepts or processes may not be repeatedly described in some embodiments.
As shown in
Referring to
A first preset distance (the first preset distance can be understood as a spacing distance in an axis direction of the vacuum wall) exists between a distal end of the inner tube 22 and the distal end of the needle rod. The distal end of the inner tube 22 is an end of inner tube 22 close to the needle tip 211. The J-T slot 1 penetrates through the inner tube 22.
In areas in which the vacuum wall is distributed in the axis direction of the vacuum wall, since the vacuum cavity plays a role in heat insulation, an area in which the cavity is located is a vacuum insulation area 26, and an area in which the first preset distance exists is a target area 25.
The distal end of the vacuum wall has at least two adjusting positions: a first adjusting position and a second adjusting position, so that the distal end of the vacuum wall can be switched between the at least two adjusting positions relative to the J-T slot (for example, switching can be realized by moving in the axis direction of the vacuum wall), the at least two adjusting positions including: a first adjusting position and a second adjusting position. When the distal end of the vacuum wall is located at the first adjusting position, the distal end of the J-T slot 1 is located in the target area 25, and it can be understood as being in a freezing mode, as shown by dashed lines in
The vacuum wall adjusting apparatus is configured to enable the distal end of the vacuum wall to be switched between the at least two adjusting positions. Specifically, the distal end of the vacuum wall can be adjusted in response to external manipulation, to be switched between the at least two adjusting positions. Furthermore, any apparatus that can realize this switching adjustment function does not depart from the description of this solution.
When the distal end of the vacuum wall is located at the first adjusting position, a second preset distance exists between the distal end of the J-T slot 1 and the needle tip 211, and the second preset distance at least ensures that an ice ball formed by freezing is wrapped around the needle tip. That is, a refrigerant fluid returns from the inside of the target area 25 and the inside of the vacuum insulation area 26 after being sprayed from the J-T slot 1, where the refrigerant fluid exchanges heat with substances outside the whole target area during the process of returning from the inside of the target area 25.
When the distal end of the vacuum wall is located at the second adjusting position, a third preset distance exists between the distal end of the J-T slot 1 and a distal end of the vacuum insulation area, and the third preset distance at least ensures that the refrigerant fluid directly returns from the inside of the vacuum insulation area after being sprayed from the J-T slot 1. Only a relatively static refrigerant exists in the target area, which will not exchange heat with the substances outside the target area. That is, the refrigerant does not release any cold in the target area during a freezing process. The distal end of the vacuum insulation area 26 is an end of the vacuum insulation area close to the needle tip 211.
When the distal end of the vacuum wall is located at the second adjusting position, the refrigerant fluid may have a certain spraying distance when being sprayed from the J-T slot 1. In order to ensure that the refrigerant fluid will not be sprayed to the target area after being sprayed from the J-T slot, a distance between the distal end of the J-T slot and the distal end of the vacuum insulation area is the third preset distance, the third preset distance being greater than or equal to the spraying distance of the refrigerant fluid. In this way, it can be ensured that the refrigerant fluid will not be sprayed to the target area after being sprayed from the J-T slot 1, and can directly return from the inside of the vacuum insulation area, thus ensuring that only the relatively static refrigerant exists in the target area.
The first preset distance, the second preset distance and the third preset distance may be understood as spacing distances in the axis direction of the vacuum wall. In addition, an axial direction mentioned later can be understood as the axis direction of the vacuum wall.
In an embodiment, the vacuum wall is a hard-material vacuum wall, which can be applied to percutaneous cryoablation instruments. As shown in
In an embodiment, the vacuum wall is a flexible-material vacuum wall, which can be applied to natural orifice transluminal ablation instruments. As shown in
In an embodiment, a use process of the cryoablation needle with the adjustable vacuum wall position is as follows: Before surgery, the cryoablation needle in the pre-purging mode is taken out to be mutually connected to a main machine. The needle rod 21 (at least the target area 25) of the cryoablation needle is inserted into physiological saline. A needling test function is enabled. A rewarming operation is firstly performed during needling test. When the temperature of the needle tip rises to a certain temperature value within a certain time, it proves that a rewarming function is normal. Then, a program automatically performs a freezing operation. When the temperature of the needle tip is reduced to a certain temperature value within a certain time, it proves that a freezing function is normal. In this case, the time the needle tip is kept at the lowest temperature can be properly prolonged for sufficient pre-purging, and then the needling test is automatically stopped. During the freezing operation, whether there is a frosting phenomenon in the vacuum insulation area 26 is observed. If there is no frosting phenomenon, it proves that a heat insulation function is normal. Whether there is air leakage in the needle tip immersed in the physiological saline is observed during the whole process. If there is not air leakage, it proves that gas tightness is normal. After the needling test, conveying pipelines of both the main machine and the cryoablation needle have been pre-purged (cooled). Then, the freezing function can be enabled (or a separately configured pre-purging function can be enabled) at first, and freezing at this stage can be carried out at a lower working pressure, or gas can be intermittently introduced, so that the temperature at the distal end of the J-T slot can be kept at the lowest temperature while gas consumption can be reduced. Next, under the condition of keeping the freezing function enabled, percutaneous puncturing can be performed under the guidance of imaging, so that the needle tip can reach an expected tumor position. In this case, the distal end of the vacuum wall can be adjusted to move toward a proximal end, and stop at the first adjusting position, to switch to the freezing mode. Since the whole conveying pipeline is already in a low temperature state, a cooling heat load of the cryoablation needle only exists in the target area 25 and tumor tissues outside the target area. Therefore, after switching to the freezing mode, the distal end of the J-T slot can still be kept at the lowest temperature, and an outer wall of the target area 25 will be reduced from room temperature to below −100° C. instantly. In this way, surgical time for ablating a tumor with the same size is shortened, or a larger ablation range (ice ball) is produced within the same time. In addition, due to more rapid cooling of the tumor tissues, the probability of intracellular ice damage of tumor cells is greatly increased, and then freezing damage of the tumor cells is more thorough and the ablation effect is better.
In a preferred embodiment, the position adjustment of the distal end of the vacuum wall adopts a vacuum wall overall adjusting (with the J-T slot 1 fixed) mode. Refer to
In an embodiment, the vacuum wall adjusting apparatus may include: a mandrel 3 and a sliding block 8. The mandrel 3 is located in an axial direction of the vacuum wall. The sliding block 8 is connected to the vacuum wall. The sliding block is located at a proximal end of the inner tube. The sliding block 8 is configured to drive the mandrel 3 to move in the axial direction, to drive the vacuum wall to move in the axial direction, so that the distal end of the vacuum wall is switched between the at least two adjusting positions. It can be seen that the sliding block 8 and the vacuum wall can be controlled to synchronously move in the axis direction.
As shown in
In the foregoing embodiment, the mandrel 3 is a first sliding block guiding portion. The sliding block 8 is arranged on an outer wall of the mandrel 3. The mandrel 3 guides the sliding block 8 to move in the axis direction. In a different embodiment, the vacuum wall may be arranged on the outer wall of the mandrel 3. The sliding block 8 may be arranged on the outer wall of the vacuum wall. The sliding block 8 moves, and then drives the vacuum wall to move along the mandrel 3. In a different embodiment, a guiding tube arranged in the axis direction of the vacuum wall can also be used for guiding. The guiding tube is arranged in the axis direction. The sliding block 8 is arranged on an inner wall of the guiding tube, slides along the guiding tube, and can also be guided to slide in the axis direction. In a different embodiment, the first sliding block guiding portion may be connected to a component to be adjusted (the vacuum wall). The sliding block is connected to the first sliding block guiding portion. The first sliding block guiding portion is arranged in the axis direction, and can move in the axis direction. The sliding block 8 drives the first sliding block guiding portion to move in the axis direction, and then drives the vacuum wall to move in the axis direction.
In an embodiment, the sliding block 8 includes: a middle fixing hole 83 and two gas intake/return tube fixing holes 85. Refer to
In an embodiment, on the basis of the foregoing embodiment of adjusting the vacuum wall integrally, in order to prevent gas in the vacuum wall from leaking during the process of adjusting a position of the distal end of the vacuum wall, the cryoablation needle with the adjustable vacuum wall position further includes a sealing assembly. Refer to
Furthermore, the sealing assembly includes: a sealing ring 51, a sealing slot 52 and a sealing press piece 53. A distal end of the sealing slot 52 is fixed to and sealed with the proximal end of the inner tube 22. The distal end of the sealing slot 52 is an end of the sealing slot close to the needle tip 211. The sealing ring 51 is placed in the sealing slot 52. The sealing press piece 53 is screwed into the sealing slot 52 in the axial direction, to fix the sealing ring 51 between the sealing slot 52 and the sealing press piece 53. The mandrel 3 is inserted into the sealing ring 51 and the sealing press piece 53, so that the sealing ring 51 is radially extruded and deformed between the mandrel 3 and the sealing slot 52 to form a dynamic seal. Optionally, the sealing ring 51 may be a rubber sealing ring, such as a Buna-N rubber O-shaped ring, or may be a low-temperature-resistant Variseal sealing ring including fluoropolymer and a metal spring.
In a preferred embodiment, the vacuum wall of the flexible cryoablation needle may further include: a vacuum tee 28, a vacuum connecting tube 291, a vacuum hose 292 and a return gas connecting tube 293. Refer to
In an embodiment, the cryoablation needle with the adjustable vacuum wall position further includes: a shunt 294, configured to seal gaps between the gas intake tube 6, the gas return tube 7 and the mandrel 3. The gas intake tube 6, the gas return tube 7 and the mandrel 3 are inserted into a proximal end of the shunt 294 for sealing. Refer to
In an embodiment, on the basis of the foregoing embodiment of adjusting the vacuum wall integrally, the position adjustment of the distal end of the vacuum wall may be achieved by manual forward and backward adjustment, or may be achieved by a prefabricated spring 120, as shown in
In a different embodiment, when the distal end of the vacuum wall is located at the second adjusting position, the spring can also be in the compression state. When the distal end of the vacuum wall is located at the first adjusting position, the spring is in the natural state.
In an embodiment, in order to facilitate grasping and adjustment, the cryoablation needle with the adjustable vacuum wall position further includes: a handle 9. The handle includes: a front handle section 92 and a rear handle section 93. Refer to
In a different embodiment, the front handle section 92 and the rear handle section 93 may not include the front limiting ring 922 and the rear limiting ring 932. Refer to
In a preferred embodiment, referring to
In an embodiment, when the cryoablation tube is flexible and includes the shunt 294, the rear adjusting section 931 of the handle is further provided with a shunt fixing hole 934 for the shunt 294 to pass through, by which the shunt is radially limited. Refer to
In an embodiment, when the cryoablation tube is flexible and includes the vacuum hose 292, the rear adjusting section 931 of the handle is further provided with a hose guiding tube 935 for the vacuum hose 292 to pass through, by which the direction of the vacuum hose is guided. Refer to
In a preferred embodiment, in order to facilitate the fixing of the clamping piece and the insertion and removal adjustment of the clamping piece, the clamping piece 10 includes: a hand-held portion 101 and a C-shaped ring 103. Refer to
In a preferred embodiment, in order to improve a heat dissipation function, the cryoablation needle with the adjustable vacuum wall position further includes: a finned tube 4. The finned tube 4 is arranged on an outer wall of the mandrel 3. Refer to
In a preferred embodiment, on the basis of the foregoing embodiment of adjusting the vacuum wall integrally, in order to increase the internal volume of the proximal end of the inner tube, for example, the finned tube 4 may be inserted into the proximal end of the inner tube, or more other components can be accommodated. Since the internal volume of the proximal end of the inner tube needs to be increased, the internal volume of the proximal end of the vacuum wall also needs to be increased. The vacuum wall further includes: an outer tube 23 and a gasket 24. Refer to
In a preferred embodiment, the position adjustment of the distal end of the vacuum wall can be achieved by adopting the mode of dividing the vacuum wall into two sections: a front vacuum wall section and a rear vacuum wall section, only adjusting the front vacuum wall section, and fixing the rear vacuum wall section. Refer to
In an embodiment, the mandrel 3 may be used as a second sliding block guiding portion. The vacuum wall is arranged on the outer wall of the mandrel 3. The sliding block 8 is arranged on the outer wall of the vacuum wall. The sliding block 8 moves, and then drives the vacuum wall to move along the mandrel 3. In a different embodiment, the sliding block 8 can also be arranged on the outer wall of the mandrel 3. The sliding block 8 is guided by the mandrel 3 to move in the axis direction. In a different embodiment, a guiding tube arranged in the axis direction of the vacuum wall can also be used for guiding. The guiding tube is arranged in the axis direction. The sliding block 8 is arranged on an inner wall of the guiding tube, slides along the guiding tube, and can also be guided to slide in the axis direction. In a different embodiment, the second sliding block guiding portion may be connected to a component to be adjusted (front vacuum wall section). The sliding block is connected to the first sliding block guiding portion. The first sliding block guiding portion is arranged in the axis direction, and can move in the axis direction. The sliding block 8 drives the first sliding block guiding portion in the axis direction, and then drives the front vacuum wall section to move in the axis direction.
In a preferred embodiment, on the basis of the foregoing embodiment of dividing the vacuum wall into two sections, an outer tube 23 is arranged at the proximal end of the needle rod 21. An outer diameter of the outer tube 23 is greater than an outer diameter of the needle rod 21, and an inner diameter of the outer tube 23 is greater than an inner diameter of the needle rod 21. Front the distal end to the proximal end of the inner tube 22, the inner tube 22 sequentially includes: an inner tube front section 221 and an inner tube rear section 222. An outer diameter of the inner tube rear section 222 is greater than an outer diameter of the inner tube front section 221. An inner diameter of the inner tube rear section 222 is greater than an inner diameter of the inner tube front section 221. The inner tube front section 221 is located inside the needle rod 21. The inner tube rear section 222 is located inside the outer tube 23. In this case, the division mode of the front vacuum wall section and the rear vacuum wall section is as follows: the front vacuum wall section includes: the needle rod 21 and the inner tube front section 221, and the rear vacuum wall section includes: the outer tube 23 and the inner tube rear section 222. In order to improve a sealing effect, the front vacuum wall section further includes: gaskets 24. The gaskets 24 are arranged between an outer wall of a distal end of the inner tube front section 221 and the needle rod 21, and between an outer wall of a proximal end of the inner tube front section 221 and the needle rod 21.
In a preferred embodiment, on the basis of the foregoing embodiment of dividing the vacuum wall into two sections, a dynamic seal is realized between the front vacuum wall section and the rear vacuum wall section through a sealing assembly, to prevent air leakage therebetween. Refer to
In a preferred embodiment, on the basis of the foregoing embodiment of dividing the vacuum wall into two sections, in order to facilitate the adjustment of the sliding block 8, the cryoablation tube with the adjustable vacuum wall position is further provided with a shifting block 86 and a handle 9. The handle 9 is provided with a handle adjusting slot 94 therein. Refer to
In a preferred embodiment, in order to better detect the freezing effect of the cryoablation needle, the cryoablation needle with the adjustable vacuum wall position further includes: a temperature measuring wire 14. A distal end of the temperature measuring wire 14 is a temperature measuring point 141, and the distal end of the temperature measuring wire 14 is an end of the temperature measuring wire 14 close to the needle tip 211. Refer to
In an embodiment, in order to wrap around components such as the gas intake tube and the gas return tube, and make the cryoablation needle cleaner in appearance and more convenient in operation, an outer sleeve 13 is further arranged on an outer wall of the handle 9. Refer to
In a preferred embodiment, the pre-purging mode, that is, a state that the distal end of the J-T slot 1 is located in the vacuum insulation area 26, can be set to a factory delivery state of the product, and an operator can directly complete the pre-purging of the product through a needling test procedure. After needling test/pre-purging is completed, the product is further adjusted to the freezing mode, that is, the distal end of the J-T slot 1 being located inside the target area 25. After the freezing mode is enabled, since the cryoablation needle is pre-purged, the target area 25 will rapidly cool down to the lowest temperature.
In the description of this specification, description of reference terms such as “an implementation”, “an embodiment”, “a specific implementation process” or “an example” means including specific features, structures, materials, or characteristics described in the embodiment or example in at least one embodiment or example of the present invention. In this specification, exemplary descriptions of the foregoing terms do not necessarily refer to the same embodiment or example. Furthermore, specific features, structures, materials or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
Finally, it should be noted that the foregoing embodiments are merely intended for describing the technical solutions of the present invention, but not for limiting the present invention. Although the present invention is described in detail with reference to the foregoing embodiments, persons of ordinary skill in the art should understand that they may still make modifications to the technical solutions described in the foregoing embodiments or make equivalent replacements to some or all technical features thereof, without making the essence of the corresponding technical solutions departing from the scope of the technical solutions of the embodiments of the present invention.
| Number | Date | Country | Kind |
|---|---|---|---|
| 202111329707.3 | Nov 2021 | CN | national |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/CN2022/128871 | 11/1/2022 | WO |
